CN104367344A - Method and device for detecting instant heart rate of fetus on basis of Shanon envelope - Google Patents

Method and device for detecting instant heart rate of fetus on basis of Shanon envelope Download PDF

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CN104367344A
CN104367344A CN201410530501.0A CN201410530501A CN104367344A CN 104367344 A CN104367344 A CN 104367344A CN 201410530501 A CN201410530501 A CN 201410530501A CN 104367344 A CN104367344 A CN 104367344A
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shannon
heart rate
signal
envelope
curve
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谢胜利
于宣福
蔡坤
冯爱
王赛红
尧永贤
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Guangdong University of Technology
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/02Measuring pulse or heart rate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/48Diagnostic techniques
    • A61B8/488Diagnostic techniques involving Doppler signals

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Abstract

The invention discloses a method and device for detecting the instant heart rate of a fetus on the basis of a Shanon envelope. The method comprises the steps of collecting the heart sound signals of the fetus; carrying out smoothing and normalization on the collected signals so as to obtain pre-processed signals; calculating the Shanon envelope according to the pre-processed signals, and drawing a Shanon envelope curve; calculating the instant heart rate of the fetus according to the Shanon envelope curve. The method is simple, the result is accurate, and the method can better serve clinic fetal monitoring. The device comprises a data collection unit, a pre-processing unit, a Shanon envelope drawing unit, an instant heart rate calculating unit, a display unit and a printing unit. The device is simple in structure, reliable in performance and convenient to use, and results are displayed directly.

Description

A kind of Fetal Instantaneous Heart Rate detection method based on Shannon envelope and device
Technical field
The present invention relates to fetal heart monitoring field, more specifically, relate to a kind of Fetal Instantaneous Heart Rate detection method based on Shannon envelope and device.
Background technology
Fetal heart monitoring a kind ofly predicts the fetus fetus monitoring method that health status is the most general in uterus.Obstetrist is just had to estimate fetal in utero situation by intermittent auscultation as far back as 19 beginnings of the century, along with the development of ultrasonic Doppler technique, the electronic fatal monitoring (electronic fetal monitoring, EFM) produced has become fetus monitoring method the most frequently used at present.Delicate change is there is not in the same time in healthy fetus with intrauterine environment, and the change of fetal heart frequency is the performance that blood circulation and central nervous system's function regulate, therefore in perinatal stage, Fetal Heart Rate detection is carried out to fetus and can understand fetus reserve capabillity in uterus, and the tolerance of weary oxygen, can reduce widely because of anoxia, ischemia and occur poverty-stricken, the Fetal Birth Defect caused, the even situation of foetal death, Timeliness coverage, timely treatment, reduce the natality of Congenital malformation fetus to greatest extent, thus improve the quality of the people of China.Therefore, Fetal Heart Rate detects has and important meaning the prenatal and postnatal care that China advocates energetically.
But, have amplitude large because the fetal heart sound gathered mostly mixes, widespread noise jamming, and the strong and weak amplitude of variation of acoustical signal when fetal body moves in mother's body is larger.In time domain and frequency domain, these interfering signals are aliasing in calculate the instantaneous heart rate of fetal heart sound signal together and cause very large impact.Therefore, it is how accurate, convenient to study, and the instantaneous heart rate effectively measuring perinatal stage fetal heart sound has and important practical value and clinical meaning.
Just someone begins one's study fetal heart monitoring a long time ago, and one of main index of fetal heart monitoring is exactly the instantaneous heart rate of fetus, and the research method of Fetal Instantaneous Heart Rate has a variety of, is broadly divided into several as follows:
(1) matching matrix based on electrocardio pattern calculates fetal heart frequency.Basic thought: first separated by Fetal ECG, secondly Fetal ECG signal R ripple location, finally asks the instantaneous heart rate of fetus.Because the requirement of matched filtering to masterplate before R ripple location is higher, mixed signal and masterplate subtract each other and require higher precision, therefore take many kinds of measures to ensure the accuracy of separation signal, more complicated choosing on masterplate, threshold value, phase place, amplitude correction, algorithm is also very lengthy and jumbled.
(2) the autocorrelative method based on hear sounds pattern calculates fetal heart frequency.As everyone knows, correlation technique extracts known waveform from additive noise, is particularly a kind of good method for deterministic periodic signal.Fetal heart rate signal is extracted with autocorrelation method, effect is good not, mainly because fetal heart sound signal has periodically, but is not deterministic periodic signal, and fetal heart sound signal waveform is also the impact being subject to fetus itself and its surrounding, the cycle is not changeless.Cycle and waveform all change with randomness and cause auto-correlation function waveform to be difficult to detect.
Summary of the invention
In order to overcome the deficiencies in the prior art, the present invention proposes a kind of Fetal Instantaneous Heart Rate detection method based on Shannon envelope, the instantaneous heart rate detecting fetus that can be fast and convenient, better serves clinical fetal monitoring.
The present invention also proposes a kind of Fetal Instantaneous Heart Rate checkout gear based on Shannon envelope, and structure is simple, dependable performance, directly shows result, easy to use.
To achieve these goals, technical scheme of the present invention is:
Based on a Fetal Instantaneous Heart Rate detection method for Shannon envelope, comprise the following steps:
S1. fetal heart sound signal is gathered;
S2. filtering, normalized are carried out to the signal gathered, obtain preprocessed signal;
S3. calculate Shannon envelope according to preprocessed signal, draw Shannon envelope curve, concrete steps are:
S31. window function is utilized to intercept preprocessed signal;
S32. based on the sampling number intercepted, the average shannon energy of signal calculated;
S33. utilize the average shannon energy obtained, the Shannon envelope of signal calculated, draw Shannon envelope curve;
S4. calculate Fetal Instantaneous Heart Rate according to Shannon envelope curve, concrete steps are:
S41. maximum detection is carried out to Shannon envelope curve;
S42. dual threshold detection is carried out to the maximum of trying to achieve, obtain the peak point of curve;
S43. based on the peak point of curve, utilize calculus of finite differences, calculate Fetal Instantaneous Heart Rate.
The Fetal Instantaneous Heart Rate detection method based on Shannon envelope that the present invention proposes, calculate simple, result accuracy rate is high, is convenient to application.
In described S2, filtering, normalized are carried out to the signal gathered, obtains preprocessed signal, specifically: by Butterworth LPF, filtering is carried out to the signal gathered, then obtain the maximum of signal absolute value, all signals divided by this maximum, obtain preprocessed signal successively.
In described S31, window function is utilized to intercept preprocessed signal, specifically: the length of window arranging window function is L second, and the overlap length of window is d second, intercepts preprocessed signal according to set window function.
In described S32, based on the sampling number intercepted, the average shannon energy of signal calculated, specifically: define according to average shannon energy, and the average shannon energy of signal calculated, average shannon energy is defined as follows:
, wherein, for preprocessed signal, N is the sampling number that window function intercepts preprocessed signal, it is the average shannon energy of t segment signal.
In described S33, utilize the average shannon energy obtained, the Shannon envelope of signal calculated, draw Shannon envelope curve, specifically: defined by Shannon envelope, the Shannon envelope of signal calculated, draw Shannon envelope curve, Shannon envelope is defined as follows:
, wherein, be the average shannon energy of t segment signal, for meansigma methods, for standard deviation, be the Shannon envelope of t segment signal.
In described S42, dual threshold detection is carried out to the maximum of trying to achieve, obtain the peak point of curve, specifically: utilize first threshold to detect the signal maximum of trying to achieve, try to achieve the peak point of curve, then carry out difference to the peak of curve point coordinates of trying to achieve, difference value and empirical value compare, the peak point utilizing Second Threshold large to difference value carries out secondary peaking, obtains all peak points of curve;
First threshold is defined as follows:
, wherein, for the value of first threshold, be 0.1, for the meansigma methods of the amplitude of all extreme points of Shannon envelope curve;
Second Threshold is defined as follows:
, wherein, for the value of Second Threshold, be 0.001, for the meansigma methods of the amplitude of all extreme points of secondary peaking part.
In described S43, based on the peak point of curve, utilize calculus of finite differences, calculate Fetal Instantaneous Heart Rate, specifically: converted by all peak point coordinates of tried to achieve curve, then carry out forward difference successively, again according to instantaneous heart rate formula, calculate Fetal Instantaneous Heart Rate, instantaneous heart rate formula is as follows:
, wherein, for the interval between every two adjacent Shannon envelopes, for instantaneous heart rate.
In described S2, the cut-off frequency fc=882Hz of Butterworth LPF.
The present invention also proposes a kind of Fetal Instantaneous Heart Rate checkout gear based on Shannon envelope, and structure is simple, easy to operate.
Specific implementation is: a kind of Fetal Instantaneous Heart Rate checkout gear based on Shannon envelope, comprising:
Data acquisition unit, for gathering fetal heart sound signal;
Pretreatment unit, for carrying out filtering, normalized to the signal gathered, obtains preprocessed signal;
Shannon envelope drawing unit, for calculating Shannon envelope according to preprocessed signal, draw Shannon envelope curve, Shannon envelope drawing unit comprises:
Signal intercepts subelement, utilizes window function to intercept preprocessed signal;
Average shannon energy computation subunit, based on the sampling number intercepted, the average shannon energy of signal calculated;
Draw subelement, utilize the average shannon energy obtained, the Shannon envelope of signal calculated, draw Shannon envelope curve;
Instantaneous heart rate calculates unit, and for calculating Fetal Instantaneous Heart Rate according to Shannon envelope curve, instantaneous heart rate calculates unit and comprises:
Maximum detection sub-unit, carries out maximum detection to Shannon envelope curve;
Dual threshold detection sub-unit, carries out dual threshold detection to the maximum of trying to achieve, and obtains the peak point of curve;
Computation subunit, based on the peak point of curve, utilizes calculus of finite differences, calculates Fetal Instantaneous Heart Rate;
Display unit, for showing the Fetal Instantaneous Heart Rate that instantaneous heart rate calculating unit obtains;
Print unit, for printing the Fetal Instantaneous Heart Rate of display unit display.
Compared with prior art, beneficial effect of the present invention is:
1) a kind of Fetal Instantaneous Heart Rate detection method based on Shannon envelope of the present invention's proposition, the instantaneous heart rate calculating fetus that can be fast and convenient, better serves clinical fetal monitoring.
2) a kind of Fetal Instantaneous Heart Rate detection method based on Shannon envelope of the present invention's proposition, result accuracy rate is high, is convenient to actual use.
3) a kind of Fetal Instantaneous Heart Rate checkout gear based on Shannon envelope of the present invention's proposition, structure is simple, dependable performance, directly shows result, easy to use.
Detailed description of the invention
Below in conjunction with accompanying drawing, the present invention will be further described, but embodiments of the present invention are not limited to this.
As shown in Figure 1, a kind of Fetal Instantaneous Heart Rate detection method based on Shannon envelope, comprises the steps:
S1. gather fetal heart sound signal, Fig. 2 is the fetal heart sound signal that ultrasound Doppler fetal heart rate detector gathers, wherein sample frequency f s=2205Hz;
S2. pretreatment, by the fetal heart sound signal that collects by Butterworth LPF filtering, the cut-off frequency f of wave filter c=882Hz, then signal amplitude is normalized, obtain the maximum of signal absolute value, by all signals successively divided by this maximum, obtain preprocessed signal, as shown in Figure 3;
S3. calculate Shannon envelope according to the preprocessed signal obtained, draw Shannon envelope curve, concrete steps are:
S31. signal intercepts, and the window function of signalization process, comprises the overlap length between length and window arranging window, intercept according to set window function to signal;
S32. average shannon energy is utilized to define, the average shannon energy of signal calculated;
S33. utilize Shannon envelope to define, the Shannon envelope of signal calculated, draw Shannon envelope curve;
Obtaining window function parameter in S31 by many experiments is: the length of window L=0.12*f of signal processing ssecond, the overlap length d=0.06*f of window ssecond; Now the value of L, d can ensure that s1 section in fetal heart rate signal and s2 section unite two into one the large envelope of formation one just, and the interval of adjacent envelope is also more clear, and according to different data, L, d also can suitably be adjusted to corresponding optimum;
In S32, average shannon energy is defined as follows:
, wherein, for preprocessed signal, N is the sampling number of window function to the intercepting of preprocessed signal, it is the average shannon energy of t segment signal; T moves along with windowsill time shaft and changes, and can obtain average shannon energy curve;
In S33, Shannon envelope is defined as follows:
, wherein, be the average shannon energy of t segment signal, for meansigma methods, for standard deviation, be the Shannon envelope of t segment signal, be also called the average aromatic energy of normalization; T moves along with windowsill time shaft and changes, and can obtain Shannon envelope curve, as shown in Figure 4;
S4. calculate Fetal Instantaneous Heart Rate according to Shannon envelope curve, concrete steps are:
S41. maximum detection is carried out to the Shannon envelope curve of trying to achieve, obtain the maximum of signal;
S42. threshold value 1 is utilized to detect trying to achieve signal maximum, try to achieve the peak point of curve, then carry out difference to the peak point coordinate of trying to achieve curve, difference value and empirical value compare, utilize the larger peak point of threshold value 2 pairs of difference values to carry out secondary peaking, obtain all peak points of curve;
Threshold value 1 is defined as follows:
, wherein, for the value of threshold value 1, the desirable arbitrary value being less than 0.1, here get 0.01, for the meansigma methods of the amplitude of all extreme points of Shannon envelope curve;
Threshold value 2 is defined as follows:
, wherein, for the value of threshold value 2, the desirable arbitrary value being less than 0.01, here get 0.001, for the meansigma methods of the amplitude of all extreme points of secondary peaking part.
S43. based on the peak point of curve, utilize calculus of finite differences, calculate Fetal Instantaneous Heart Rate; All peak point coordinates of tried to achieve curve are carried out relevant conversion, then carry out forward difference successively, then try to achieve the instantaneous heart rate of fetus according to instantaneous heart rate formula, wherein instantaneous heart rate formula is as follows:
, wherein for the interval between every two adjacent Shannon envelopes, for instantaneous heart rate, the Fetal Instantaneous Heart Rate calculated as shown in Figure 5.
The present invention also proposes a kind of Fetal Instantaneous Heart Rate checkout gear based on Shannon envelope, calculates Fetal Instantaneous Heart Rate quickly and easily, is convenient to application.
As shown in Figure 6, a kind of Fetal Instantaneous Heart Rate blood processor based on Shannon envelope, comprising specific implementation:
Data acquisition unit, for gathering fetal heart sound signal;
Pretreatment unit, for carrying out filtering, normalized to the signal gathered, obtains preprocessed signal;
Shannon envelope drawing unit, for calculating Shannon envelope according to preprocessed signal, drawing Shannon envelope curve, specifically comprising as shown in Figure 7:
Signal intercepts subelement, utilizes window function to intercept preprocessed signal;
Average shannon energy computation subunit, based on the sampling number intercepted, the average shannon energy of signal calculated;
Draw subelement, utilize the average shannon energy obtained, the Shannon envelope of signal calculated, draw Shannon envelope curve;
Instantaneous heart rate calculates unit, for calculating Fetal Instantaneous Heart Rate according to Shannon envelope curve, specifically comprises as shown in Figure 8:
Maximum detection sub-unit, carries out maximum detection to Shannon envelope curve;
Dual threshold detection sub-unit, carries out dual threshold detection to the maximum of trying to achieve, and obtains the peak point of curve;
Computation subunit, based on the peak point of curve, utilizes calculus of finite differences, calculates Fetal Instantaneous Heart Rate;
Display unit, for showing the Fetal Instantaneous Heart Rate that instantaneous heart rate calculating unit obtains;
Print unit, for printing the Fetal Instantaneous Heart Rate of display unit display.
A kind of Fetal Instantaneous Heart Rate detection method based on Shannon envelope that the present invention proposes, the instantaneous heart rate calculating fetus that can be fast and convenient, better serves clinical fetal monitoring.
A kind of Fetal Instantaneous Heart Rate detection method based on Shannon envelope that the present invention proposes, result accuracy rate is high, is convenient to actual use.
A kind of Fetal Instantaneous Heart Rate checkout gear based on Shannon envelope that the present invention proposes, structure is simple, dependable performance, directly shows result, easy to operate.
Above-described embodiments of the present invention, do not form limiting the scope of the present invention.Any amendment done within spiritual principles of the present invention, equivalent replacement and improvement etc., all should be included within claims of the present invention.
Accompanying drawing explanation
Fig. 1 is the flow chart of the Fetal Instantaneous Heart Rate detection method based on Shannon envelope of the present invention.
Fig. 2 is the fetal heart sound signal figure that ultrasound Doppler fetal heart rate detector gathers.
Fig. 3 is the fetal heart sound preprocessed signal figure that the present invention obtains.
Fig. 4 is the Shannon envelope curve figure that the present invention obtains.
Fig. 5 is the Fetal Instantaneous Heart Rate figure that the present invention calculates.
Fig. 6 is the structural representation of the Fetal Instantaneous Heart Rate checkout gear based on Shannon envelope of the present invention.
Fig. 7 is the structural representation of Shannon envelope drawing unit in Fig. 6.
Fig. 8 is the structural representation that in Fig. 6, instantaneous heart rate calculates unit.

Claims (9)

1., based on a Fetal Instantaneous Heart Rate detection method for Shannon envelope, it is characterized in that, comprising:
S1. fetal heart sound signal is gathered;
S2. filtering, normalized are carried out to the signal gathered, obtain preprocessed signal;
S3. calculate Shannon envelope according to preprocessed signal, draw Shannon envelope curve, concrete steps are:
S31. window function is utilized to intercept preprocessed signal;
S32. based on the sampling number intercepted, the average shannon energy of signal calculated;
S33. utilize the average shannon energy obtained, the Shannon envelope of signal calculated, draw Shannon envelope curve;
S4. calculate Fetal Instantaneous Heart Rate according to Shannon envelope curve, concrete steps are:
S41. maximum detection is carried out to Shannon envelope curve;
S42. dual threshold detection is carried out to the maximum of trying to achieve, obtain the peak point of curve;
S43. based on the peak point of curve, utilize calculus of finite differences, calculate Fetal Instantaneous Heart Rate.
2. the Fetal Instantaneous Heart Rate detection method based on Shannon envelope according to claim 1, it is characterized in that, in described S2, filtering, normalized are carried out to the signal gathered, obtain preprocessed signal, specifically: by Butterworth LPF, filtering is carried out to the signal gathered, then obtain the maximum of signal absolute value, all signals divided by this maximum, obtain preprocessed signal successively.
3. the Fetal Instantaneous Heart Rate detection method based on Shannon envelope according to claim 2, it is characterized in that, in described S31, window function is utilized to intercept preprocessed signal, specifically: the length of window arranging window function is L second, the overlap length of window is d second, intercepts preprocessed signal according to set window function.
4. the Fetal Instantaneous Heart Rate detection method based on Shannon envelope according to claim 3, it is characterized in that, in described S32, based on the sampling number intercepted, the average shannon energy of signal calculated, specifically: define according to average shannon energy, the average shannon energy of signal calculated, average shannon energy is defined as follows:
, wherein, for preprocessed signal, N is the sampling number that window function intercepts preprocessed signal, it is the average shannon energy of t segment signal.
5. the Fetal Instantaneous Heart Rate detection method based on Shannon envelope according to claim 4, it is characterized in that, in described S33, utilize the average shannon energy obtained, the Shannon envelope of signal calculated, draw Shannon envelope curve, specifically: defined by Shannon envelope, the Shannon envelope of signal calculated, draw Shannon envelope curve, Shannon envelope is defined as follows:
, wherein, be the average shannon energy of t segment signal, for meansigma methods, for standard deviation, it is the Shannon envelope of t segment signal.
6. the Fetal Instantaneous Heart Rate detection method based on Shannon envelope according to claim 5, it is characterized in that, in described S42, dual threshold detection is carried out to the maximum of trying to achieve, obtain the peak point of curve, specifically: utilize first threshold to detect the signal maximum of trying to achieve, try to achieve the peak point of curve, again difference is carried out to the peak of curve point coordinates of trying to achieve, difference value and empirical value compare, the peak point utilizing Second Threshold large to difference value carries out secondary peaking, obtains all peak points of curve;
First threshold is defined as follows:
, wherein, for the value of first threshold, be 0.1, for the meansigma methods of the amplitude of all extreme points of Shannon envelope curve;
Second Threshold is defined as follows:
, wherein, for the value of Second Threshold, be 0.001, for the meansigma methods of the amplitude of all extreme points of secondary peaking part.
7. the Fetal Instantaneous Heart Rate detection method based on Shannon envelope according to claim 6, it is characterized in that, in described S43, based on the peak point of curve, utilize calculus of finite differences, calculate Fetal Instantaneous Heart Rate, specifically: all peak point coordinates of tried to achieve curve are converted, then carries out forward difference successively, then according to instantaneous heart rate formula, calculate Fetal Instantaneous Heart Rate, instantaneous heart rate formula is as follows:
, wherein, for the interval between every two adjacent Shannon envelopes, for instantaneous heart rate.
8. the Fetal Instantaneous Heart Rate detection method based on Shannon envelope according to claim 7, is characterized in that, in described S2, and the cut-off frequency fc=882Hz of Butterworth LPF.
9., based on a Fetal Instantaneous Heart Rate checkout gear for Shannon envelope, it is characterized in that, comprising:
Data acquisition unit, for gathering fetal heart sound signal;
Pretreatment unit, for carrying out filtering, normalized to the signal gathered, obtains preprocessed signal;
Shannon envelope drawing unit, for calculating Shannon envelope according to preprocessed signal, draw Shannon envelope curve, Shannon envelope drawing unit comprises:
Signal intercepts subelement, utilizes window function to intercept preprocessed signal;
Average shannon energy computation subunit, based on the sampling number intercepted, the average shannon energy of signal calculated;
Draw subelement, utilize the average shannon energy obtained, the Shannon envelope of signal calculated, draw Shannon envelope curve;
Instantaneous heart rate calculates unit, and for calculating Fetal Instantaneous Heart Rate according to Shannon envelope curve, instantaneous heart rate calculates unit and comprises:
Maximum detection sub-unit, carries out maximum detection to Shannon envelope curve;
Dual threshold detection sub-unit, carries out dual threshold detection to the maximum of trying to achieve, and obtains the peak point of curve;
Computation subunit, based on the peak point of curve, utilizes calculus of finite differences, calculates Fetal Instantaneous Heart Rate;
Display unit, for showing the Fetal Instantaneous Heart Rate that instantaneous heart rate calculating unit obtains;
Print unit, for printing the Fetal Instantaneous Heart Rate of display unit display.
CN201410530501.0A 2014-10-10 2014-10-10 Method and device for detecting instant heart rate of fetus on basis of Shanon envelope Pending CN104367344A (en)

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