CN104365589A - Pesticide suspension agent containing methanesulfonylzole - Google Patents
Pesticide suspension agent containing methanesulfonylzole Download PDFInfo
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- CN104365589A CN104365589A CN201410556656.1A CN201410556656A CN104365589A CN 104365589 A CN104365589 A CN 104365589A CN 201410556656 A CN201410556656 A CN 201410556656A CN 104365589 A CN104365589 A CN 104365589A
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Abstract
The invention provides a pesticide suspension agent containing methanesulfonylzole. The pesticide suspension agent comprises the active component methanesulfonylzole with the effective amount, a wetting agent, a dispersant, a de-foaming agent, a thickening agent, a preservative, water and an anti-freezing agent. According to the pesticide suspension agent provided by the invention, the suitable wetting agent is selected and is matched with other auxiliary agents to prepare the suspension agent containing the methanesulfonylzole; and the suspension agent has high suspension rate, good stability and good prevention and treatment effects.
Description
Technical field
The invention belongs to technical field of pesticide, particularly relate to a kind of agricultural chemicals suspension agent.
Background technology
For the great disease problem of agricultural, carry out the guide structure optimizing research of disease regulation and control, find safety scientific and efficiently and have green candidate's agricultural chemicals of potential market vitality to be the vital task faced in China's New pesticides discovery basic research.Guide finds it is the key realizing innovation green chemical pesticide, and design optimization synthesizes some class agricultural chemicals guide structures, the green chemical pesticide of development of new low toxicity, low-residual, safety, seems very urgent and important.2007, Guizhou University's fine chemistry industry center with the lead compound gallic acid filtered out in natural products for initiation material, design and synthesis a series of newly containing 1,3,4-thiophene (Evil) di azoly sulfone (sulfoxide) derivative, adopt growth rate method, with fusarium graminearum (
gibberella zeae), botrytis cinerea pers (
botrytis cinerea), Sclerotinia sclerotiorum (
sclerotinia sclerotiorum) etc. disease be tested object, bacteriostatic activity research has been carried out to partial target compound.Result shows, its EC of partial target compound
50value between 2.9-23.3mg/mL, have well suppress disease activity [
bioorg. Med. Chem. 2007,
15, 3981;
bioorg. & Med. Chem.
2008, 16,3632.].
On this basis, carry out more deep study on the synthesis, find methylsulfonyl bacterium azoles (Universal Chinese character name, the Secretariat of national pesticide standard technical committee names), molecular formula: C
9h
7fN
2o
3s.
Under 75-150 gram/ha of consumption, methylsulfonyl bacterium azoles has excellent preventive effect (test approval number: SY 201303170, SY 201400217) to bacteriosises such as bacterial blight of rice, bacterial leaf streak of rice, bacterial wilt of tomato and fruit tree cankers.
Methylsulfonyl bacterium azoles physicochemical property: molecular weight 242.02.Former medicine is acicular crystal, fusing point 102-104 DEG C.Water insoluble, be soluble in conventional organic solvent.Former medicine, to light, thermally-stabilised, easily decomposes under alkali condition (pH10).
Methylsulfonyl bacterium azoles mammalian toxicity: rat acute per os LD
50>383mg/kg.Rat acute is through skin and suck LD
50>2000mg/kg.To the medium stimulation of Rabbits with Acute skin, to the weak sensitization of guinea pig skin.
Methylsulfonyl bacterium azoles eco-toxicity: to Japanese quail acute oral LD
50>2000mg/kg.bw, to newbora baky earthworm honeybee Acute exposure LC
50(14 d) is 138 mg a.i./kg
dry ground,to goat's horn crescent moon algae acute toxicity EC
50(72 h) is 2.54 mg a.i./L, to the half-inhibition concentration EC of Daphnia magna
50(48 h) is 2.31 mg a.i./L.
The present invention is the suspending agent of open methylsulfonyl bacterium azoles.
Summary of the invention
A kind of agricultural chemicals suspension agent, includes the active component methylsulfonyl bacterium azoles of effective amount, and wetting agent, dispersant, defoamer, thickener, antifreeze, preservative and water, and wherein this is as follows for each component and weight percent thereof:
Methylsulfonyl bacterium azoles 5-60%
Wetting agent 1-5%
Dispersant 2-8%
Antifreeze 0.1-10%
Defoamer 0.1-2%%
Thickener 0.1-3%
Preservative 0.1-3%
Water supplies 100%.
Described wetting agent is alkyl phenol formaldehyde resin polyoxyethylene ether, the one in lauryl sodium sulfate, neopelex, polyether-modified polysiloxane, Nekal BX or 2-3 kind;
Described dispersant is that poly-naphthalene formaldehyde sulfonate salt, lignosulfonates, naphthalene sulfonic acid-formaldehyde condensation product sodium salt, alkylphenol-polyethenoxy are phonetic, one in sodium methylene bis-naphthalene sulfonate or 2-3 kind;
Described defoamer is the one in dimethyl silicone polymer, silicone oil, isooctanol, n-octyl alcohol;
Described thickener is one in xanthans, gum Arabic, sodium alginate, aluminium-magnesium silicate or 2 kinds;
Described antifreeze is one in ethylene glycol, propane diols, glycerine, urea or 2 kinds;
Described preservative is one in Sodium Benzoate, Kathon CG, lactic acid or 2 kinds;
Described suspending agent, for preventing and treating the purposes of crop pest, is characterized in that, the material of attacking by suspending agent process disease or the disease of effective dose, plant, region, soil, seed or space.
Embodiment
Embodiment 1 20% methylsulfonyl bacterium azole suspending agent
Weigh methylsulfonyl bacterium azoles (content 93%) 21.8g, alkyl phenol formaldehyde resin polyoxyethylene ether 2g, lignosulfonates 5g, propane diols 4g, dimethyl silicone polymer 0.8g, gum Arabic 0.2g, Kathon CG 0.2g, water 66g fully mixes, disperses, and enters sand mill sand milling after being uniformly dispersed, and sand milling to particle diameter 90% is less than 5 microns and namely obtains 20% methylsulfonyl bacterium azole suspending agent.
Embodiment 2 20% methylsulfonyl bacterium azole suspending agent
Weigh methylsulfonyl bacterium azoles (content 93%) 21.8g, neopelex 1.5 g, alkylphenol polyoxyethylene 4g, dimethyl silicone polymer 1g, xanthans 1g, ethylene glycol 3g, Sodium Benzoate 0.5g, water 67.2g fully mixes, disperses, and enters sand mill sand milling after being uniformly dispersed, and sand milling to particle diameter 90% is less than 5 microns and namely obtains 20% methylsulfonyl bacterium azole suspending agent.
Embodiment 3 20% methylsulfonyl bacterium azole suspending agent
Weigh methylsulfonyl bacterium azoles (content 93%) 21.8g, polyether-modified polysiloxane 1g, sodium methylene bis-naphthalene sulfonate 4g, silicone oil 1g, sodium alginate 1.2g, urea 4g, benzene Kathon CG 0.4g, water 66.6g fully mixes, disperses, and enters sand mill sand milling after being uniformly dispersed, and sand milling to particle diameter 90% is less than 5 microns and namely obtains 20% methylsulfonyl bacterium azole suspending agent.
Embodiment 4 20% methylsulfonyl bacterium azole suspending agent
Weigh methylsulfonyl bacterium azoles (content 93%) 21.8g, alkyl phenol formaldehyde resin polyoxyethylene ether 0.5g, Nekal BX 0.5g, sodium methylene bis-naphthalene sulfonate 4g, dimethyl silicone polymer 1.2g, sodium alginate 1.2g, urea 5g, benzene Kathon CG 0.5g, water 65.3g fully mixes, disperses, enter sand mill sand milling after being uniformly dispersed, sand milling to particle diameter 90% is less than 5 microns and namely obtains 20% methylsulfonyl bacterium azole suspending agent.
Embodiment 5 30% methylsulfonyl bacterium azole suspending agent
Weigh methylsulfonyl bacterium azoles (content 93%) 31.8g, polyether-modified polysiloxane 0.5g, alkyl phenol formaldehyde resin polyoxyethylene ether 0.5g, naphthalene sulfonic acid-formaldehyde condensation product sodium salt 4g, isooctanol 1.2g, aluminium-magnesium silicate 1g, xanthans 0.5g, urea 2g,, Kathon CG 0.5g, water 57.5g fully mixes, disperses, enter sand mill sand milling after being uniformly dispersed, sand milling to particle diameter 90% is less than 5 microns and namely obtains 30% methylsulfonyl bacterium azole suspending agent.
Embodiment 6 40% methylsulfonyl bacterium azole suspending agent
Weigh methylsulfonyl bacterium azoles (content 93%) 41.8g, lauryl sodium sulfate 2g, polyether-modified polysiloxane 0.5g, poly-naphthalene formaldehyde sulfonate salt 4g, sodium methylene bis-naphthalene sulfonate 1.2g, silicone oil 1.2g, aluminium-magnesium silicate 2g, xanthans 0.8g, ethylene glycol 2g, Kathon CG 0.5g, water 44g, enter sand mill sand milling after being uniformly dispersed, sand milling to particle diameter 90% is less than 5 microns and namely obtains 40% methylsulfonyl bacterium azole suspending agent.
The performance of embodiment 7 methylsulfonyl bacterium azole suspending agent
To be correlated with agricultural chemicals national standard or professional standard (GB/T14825-2006 agricultural-chemical suspension rate assay method according to China, GB/T19136-2003 agricultural chemicals heat storage stability assay method, GB/T19137-2003 agricultural chemicals low-temperature stability assay method, HG/T2467.5-2003 agricultural chemicals suspension agent product standard writes specification) regulation, measure methylsulfonyl bacterium azole suspending agent the key technical indexes of the present invention, it is as shown in the table for result:
| Numbering | Effective content (%) | Outward appearance/stickiness | Suspensibility (%) | Low-temperature stability | Heat storage stability |
| Embodiment 1 | 20.1 | The good white suspension of mobility | 89.9 | Qualified | Qualified |
| Embodiment 2 | 19.9 | The good white suspension of mobility | 92.2 | Qualified | Qualified |
| Embodiment 3 | 20.2 | The good white suspension of mobility | 91.3 | Qualified | Qualified |
| Embodiment 4 | 20.1 | The good white suspension of mobility | 90.8 | Qualified | Qualified |
| Embodiment 5 | 30.2 | The good white suspension of mobility | 91.3 | Qualified | Qualified |
| Embodiment 6 | 40.3 | The good white suspension of mobility | 92 | Qualified | Qualified |
Conclusion
The present invention is a kind of agricultural chemicals suspension agent, and 20% methylsulfonyl bacterium azole suspending agent better performances, suspensibility is high.
Claims (8)
1. an agricultural chemicals suspension agent, includes the active component methylsulfonyl bacterium azoles of effective amount, and wetting agent, dispersant, defoamer, thickener, antifreeze, preservative and water, wherein each component and percentage by weight as follows:
Methylsulfonyl bacterium azoles 5-60%
Wetting agent 1-5%
Dispersant 2-8%
Antifreeze 0.1-10%
Defoamer 0.1-2%%
Thickener 0.1-3%
Preservative 0.1-3%
Water supplies 100%.
2. described a kind of agricultural chemicals suspension agent according to claim 1, it is characterized in that described wetting agent is alkyl phenol formaldehyde resin polyoxyethylene ether, the one in lauryl sodium sulfate, neopelex, polyether-modified polysiloxane, Nekal BX or 2-3 kind.
3. described a kind of agricultural chemicals suspension agent according to claim 1, is characterized in that described dispersant is one in poly-naphthalene formaldehyde sulfonate salt, lignosulfonates, naphthalene sulfonic acid-formaldehyde condensation product sodium salt, alkylphenol polyoxyethylene, sodium methylene bis-naphthalene sulfonate or 2-3 kind.
4. described a kind of agricultural chemicals suspension agent according to claim 1, is characterized in that described defoamer is the one in dimethyl silicone polymer, silicone oil, isooctanol, n-octyl alcohol.
5. described a kind of agricultural chemicals suspension agent according to claim 1, is characterized in that described thickener is one or both in xanthans, gum Arabic, sodium alginate, aluminium-magnesium silicate.
6. described a kind of agricultural chemicals suspension agent according to claim 1, is characterized in that described antifreeze is one or both in ethylene glycol, propane diols, glycerine, urea.
7. described a kind of agricultural chemicals suspension agent according to claim 1, is characterized in that described preservative is one or both in Sodium Benzoate, Kathon CG, lactic acid.
8. described a kind of agricultural chemicals suspension agent as claimed in claim 1, for preventing and treating the purposes of crop pest, is characterized in that, the material of attacking by suspending agent process disease or the disease of effective dose, plant, region, soil, seed or space.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410556656.1A CN104365589A (en) | 2014-10-20 | 2014-10-20 | Pesticide suspension agent containing methanesulfonylzole |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410556656.1A CN104365589A (en) | 2014-10-20 | 2014-10-20 | Pesticide suspension agent containing methanesulfonylzole |
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|---|---|
| CN104365589A true CN104365589A (en) | 2015-02-25 |
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| CN201410556656.1A Pending CN104365589A (en) | 2014-10-20 | 2014-10-20 | Pesticide suspension agent containing methanesulfonylzole |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112673870A (en) * | 2020-12-07 | 2021-04-20 | 嘉应学院 | Method for interplanting honeysuckle and polygonum multiflorum in hillside orchard |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0486798A1 (en) * | 1990-10-20 | 1992-05-27 | Bayer Ag | Fungicidal agents based on heterocyclic substituted sulphones |
| CN101812034A (en) * | 2010-05-11 | 2010-08-25 | 贵州大学 | 2-substituent-5-(2,4-dichlorophenyl)-1,3,4-oxadiazole derivative, synthetic method and application thereof |
| CN102499247A (en) * | 2011-10-17 | 2012-06-20 | 贵州大学 | Oxadiazole sulfone compound for controlling bacterial crop diseases |
-
2014
- 2014-10-20 CN CN201410556656.1A patent/CN104365589A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0486798A1 (en) * | 1990-10-20 | 1992-05-27 | Bayer Ag | Fungicidal agents based on heterocyclic substituted sulphones |
| CN101812034A (en) * | 2010-05-11 | 2010-08-25 | 贵州大学 | 2-substituent-5-(2,4-dichlorophenyl)-1,3,4-oxadiazole derivative, synthetic method and application thereof |
| CN102499247A (en) * | 2011-10-17 | 2012-06-20 | 贵州大学 | Oxadiazole sulfone compound for controlling bacterial crop diseases |
Non-Patent Citations (1)
| Title |
|---|
| 郭武棣等: "《农药剂型加工丛书 第三版 液体制剂》", 31 January 2004 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112673870A (en) * | 2020-12-07 | 2021-04-20 | 嘉应学院 | Method for interplanting honeysuckle and polygonum multiflorum in hillside orchard |
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Application publication date: 20150225 |