CN104353024A - Analgesic bone ointment paste and preparation method thereof - Google Patents

Analgesic bone ointment paste and preparation method thereof Download PDF

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CN104353024A
CN104353024A CN201410560434.7A CN201410560434A CN104353024A CN 104353024 A CN104353024 A CN 104353024A CN 201410560434 A CN201410560434 A CN 201410560434A CN 104353024 A CN104353024 A CN 104353024A
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parts
radix
ointment
wine
knit
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罗先军
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SUZHOU RENJIERUI AUTOMATION TECHNOLOGY Co Ltd
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SUZHOU RENJIERUI AUTOMATION TECHNOLOGY Co Ltd
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
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    • A61K36/46Eucommiaceae (Eucommia family), e.g. hardy rubber tree
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms

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Abstract

The invention discloses an analgesic bone ointment paste and a preparation method thereof. The analgesic bone ointment paste comprises an adhesive patch and ointment coated on the adhesive patch, wherein the ointment is mainly made of the following raw materials in part by weight: 20-40 parts of radix onosmatis, 30-60 parts of angelica sinensis, 10-20 parts of ginger, 12-30 parts of arivela viscosa, 9-16 parts of elderberry, 5-10 parts of twig and leaf of common tupidanthus, 8-20 parts of turmeric, 30-50 parts of eucommia ulmoides, 10-16 parts of lycopodium clavatum, 9-25 parts of notoginseng, 12-24 parts of radix dipsaci, 15-25 parts of catecholamine, 180-260 parts of oil, 180-260 parts of Vaseline and 220-350 parts of wine. Compared with the prior art, the analgesic bone ointment paste has the benefits that the formula is scientific, the compatibility is rational, and no toxic or side effect and no bad reaction exist; any artificial fixing ways of fixing a clamping plate, being in a plaster cast, binding and the like are not needed, so that the patient's pain is relieved, and meanwhile, the patient's economic burden is also reduced; the healing period is short, and the paste takes effect quickly.

Description

A kind of alleviate pain and knit the fractured bone medical ointment plaster and preparation method thereof
Technical field
The invention belongs to important technology field, relate to a kind of pharmaceutical composition for the treatment of traumatic injury, fracture tendon breaking, particularly relate to a kind of alleviate pain and knit the fractured bone medical ointment plaster and preparation method thereof.
Background technology
Fracture mainly refers to that the seriality of the bone structure caused by wound is by a kind of disease partially or completely ruptured, and is common surgical disease.Be more common in child and old people, young people also happens occasionally.Patient Chang Weiyi position fracture, minority is multiple fracture.It brings great pain to wounded body, gently then several months, can not recover even more for a long time more than heavy then year.
Delayed union of fracture or for a long time disunion happen occasionally the life and work capacity that have a strong impact on patient.The healing of fracture refers to the tissue repair reaction between fracture site.Newborn process of repairing is completed jointly by intermembranous ossification and endochondral ossification.The process of union of fracture is also be transitioned into permanent firm connection procedure by temporary urgent connection, is a continuously process.
At present, doctor trained in Western medicine many employings operative treatment, is all generally adopt first to be fixed after fracture site righting fracture site with the utensil such as steel wire, clamping plate again, then fixes with Gypsum Fibrosum, binder.This method mainly relies on patient's autosynthesis ability that fracture site is engaged naturally, or some blood circulation promoting and blood stasis dispelling, anti-inflammatory analgetic class medicine are taken in cooperation.The shortcoming of this Therapeutic Method is that its treatment cycle is long, and costly, bone tissue growth is slow, treatment cycle is long, and overlap displacement in various degree easily appears in fracture site simultaneously, and cause swelling pain to aggravate, cause and stretch miopragia in the wrong or forfeiture, patient is very painful.
Through appropriate process in time, as reset, fixing, functional exercise, most patient can recover original function, and a few patients can leave over sequela in various degree.But the medicine of existing treatment fracture, there is the shortcomings such as alleviating pain and detumescence is slow, the course for the treatment of is long, and effect is undesirable, needs of patients stands long pain, needs to improve.
Application number be 201310100992.0 Chinese patent disclose the patent of invention that a kind of denomination of invention is " bone-set plaster and preparation method thereof ", this bone-set plaster respectively forms primarily of following raw materials according system, is weight portion: Radix Angelicae Sinensis 50-120 part, Myrrha 30-60 parts, Semen Strychni 10-15 part, Pyritum 15-25 parts, Sanguis Draxonis 15-25 part, Rhizoma Zingiberis Recens 15-20 part, Herba Spilanthis callimorphae 20-35 part, Fructus Aurantii 20-40 part, Radix Glycyrrhizae 8-15 part.This patent of invention also discloses the preparation method of bone-set plaster simultaneously, comprise the following steps as follows: be crushed into powder after each raw material is dried, mix homogeneously, then mixes furnishing paste with micro-cool vegetable oil after heating and vaseline by the weight ratio of 1:2 mono-3:1 1 by above-mentioned mixed-powder.
The Chinese patent of application number 201310550873.5 discloses the patent of invention that a kind of denomination of invention is " bone-knitting Chinese medicament and preparation method thereof ", this bone-knitting Chinese medicament is made primarily of the crude drug of following parts by weight: Herba Taraxaci 10-15 part, Herba Schizonepetae 4.5-9 part, Herba Ephedrae 2-9 part, Radix Salviae Miltiorrhizae 5-15 part, Ramulus et Folium Tupidanthi celyptrati 9-15 part, schefflera arboricola 6-18 part, Rhizoma seu Herba Elatostematis stewardii 9-15 part, Myrrha 10-20 part, Olibanum 5-15 part, Semen Persicae 4.5-9 part, Flos Carthami 3-10 part, Rhizoma Curcumae Longae 3-10 part, Semen Vaccariae 5-10 part, Flos Campsis 5-10 part, Resina Liquidambaris 3-6 part, Folium et Ramulus Clerodendri Trichotomi 10-20 part, Herba Aristolochiae Mollissimae 10-20 part, Ramulus Sambuci Williamsii 10-20 part.This patent of invention also discloses the preparation method of bone-knitting Chinese medicament, comprises the following steps: be crushed into powder by above-mentioned raw materials medicine, mix homogeneously, then powder and Oleum Brassicae campestris, vaseline is mixed and made into paste.Claim that therapeutic effect is good.
Summary of the invention
The present invention needs the problems referred to above solved to be for above-mentioned the deficiencies in the prior art, and provides a kind of alleviate pain and knit the fractured bone medical ointment plaster and preparation method thereof.
For solving the problems of the technologies described above, the technical solution used in the present invention is:
A kind of alleviate pain and knit the fractured bone medical ointment plaster, comprise sticker sheet and be coated in the ointment on sticker sheet, described ointment is made primarily of the raw material of following parts by weight: Radix onosmatis 20-40 part, Radix Angelicae Sinensis 30-60 part, Rhizoma Zingiberis Recens 10-20 part, Herba Spilanthis callimorphae 12-30 part, Ramulus Sambuci Williamsii 9-16 part, Ramulus et Folium Tupidanthi celyptrati 5-10 part, Rhizoma Curcumae Longae 8-20 part, Cortex Eucommiae 30-50 part, Herba Lycopodii 10-16 part, Radix Notoginseng 9-25 part, Radix Dipsaci 12-24 part, catechu 15-25 part, oily 180-260 part, vaseline 180-260 part, wine 220-350 part.
As preferably, described ointment is made primarily of the raw material of following parts by weight:
Radix onosmatis 20 parts, Radix Angelicae Sinensis 30 parts, 10 parts, Rhizoma Zingiberis Recens, Herba Spilanthis callimorphae 12 parts, Ramulus Sambuci Williamsii 9 parts, Ramulus et Folium Tupidanthi celyptrati 5 parts, 8 parts, Rhizoma Curcumae Longae, the Cortex Eucommiae 30 parts, Herba Lycopodii 10 parts, Radix Notoginseng 9 parts, Radix Dipsaci 12 parts, 15 parts, catechu, oil 180 parts, 180 parts, vaseline, wine 220 parts.
As preferably, described ointment is made primarily of the raw material of following parts by weight:
Radix onosmatis 40 parts, Radix Angelicae Sinensis 60 parts, 20 parts, Rhizoma Zingiberis Recens, Herba Spilanthis callimorphae 30 parts, Ramulus Sambuci Williamsii 16 parts, Ramulus et Folium Tupidanthi celyptrati 10 parts, 20 parts, Rhizoma Curcumae Longae, the Cortex Eucommiae 50 parts, Herba Lycopodii 16 parts, Radix Notoginseng 25 parts, Radix Dipsaci 24 parts, 25 parts, catechu, oil 260 parts, 260 parts, vaseline, wine 350 parts.
As preferably, described ointment is made primarily of the raw material of following parts by weight:
Radix onosmatis 30 parts, Radix Angelicae Sinensis 50 parts, 15 parts, Rhizoma Zingiberis Recens, Herba Spilanthis callimorphae 20 parts, Ramulus Sambuci Williamsii 12 parts, Ramulus et Folium Tupidanthi celyptrati 8 parts, 15 parts, Rhizoma Curcumae Longae, the Cortex Eucommiae 40 parts, Herba Lycopodii 15 parts, Radix Notoginseng 18 parts, Radix Dipsaci 20 parts, 20 parts, catechu, oil 200 parts, 130 parts, vaseline, wine 300 parts.
Described oil is vegetable oil.
Described wine is rice wine.
The preparation method of above-mentioned alleviate pain and knit the fractured bone medical ointment plaster, is crushed into powder after being dried by above-mentioned each raw material, and mix homogeneously, then by furnishing paste in rear to above-mentioned mixed-powder and heating micro-cool oil, wine and vaseline, and then paste is coated on sticker sheet.
Each raw material effect of JIEGU GAO plaster of the present invention is as follows:
Radix onosmatis, nature and flavor: sweet are cool.Function with cure mainly: clearing away heat and cooling blood, support lung, for pneumonia, tuberculous cavity, high mountain plethora.
Radix Angelicae Sinensis, the dry root of umbelliferae angelica.Warm in nature, sweet in the mouth, has and enriches blood and invigorate blood circulation, expelling wind and cold, and evacuation of pus is pain.
Rhizoma Zingiberis Recens, the fresh rhizome of zingiber.Acrid in the mouth, warm in nature, temperature is logical invigorates blood circulation.
Herba Spilanthis callimorphae, has another name called little anaesthetic, and be the herb of feverfew bristle fruit vetch, property is put down, acrid in the mouth, can promoting blood circulation and hemostasis.
Ramulus Sambuci Williamsii, have anti-inflammation, heat-clearing and toxic substances removing, expelling wind and removing dampness, promoting blood circulation and stopping pain, effects such as synthetism of stimulating the menstrual flow, be used for the treatment of various diseases associated with inflammation, rheumatic arthritis, lumbago and skelalgia, sore swollen toxin pneumonia, appendicitis, acute cellulitis, tumor, traumatic injury, fracture etc.
Ramulus et Folium Tupidanthi celyptrati, meridian distribution of property and flavor: bitter, temperature.Enter lung, kidney,liver,spleen four warp.Effect: relaxing muscles and tendons and activating QI and blood in the collateral, circulation of qi promoting damp eliminating, cold expelling dispels the wind, eliminating dampness to stop diarrhea.Cure mainly: for traumatic injury, fracture pain person, the arthralgia aggravated by cold of cold and damp stagnation, affection of exogenous wind-cold, heating fear of cold, head-body-pain.For abdominal part distension, malaise, anorexia, poor appetite, dysentery person.
Rhizoma Curcumae Longae, nature and flavor: bitter in the mouth; Pungent; Warm in nature.Gui Jing: spleen channel; Liver Channel.Effect: removing blood stasis circulation of qi promoting; Inducing menstruation to relieve menalgia.Cure mainly: all cards of stagnation of QI and blood; Born of the same parents' abdomen hypochondriac pain; Dysmenorrhes; Amenorrhea; The stagnant stomachache of the stasis of blood in puerperal; Rheumatic arthralgia; Traumatic injury; Carbuncle.
The Cortex Eucommiae, the dry bark of the Eucommiaceae plant Cortex Eucommiae is Chinese famous and precious tonic herb.Sweet in the mouth, warm in nature.Return liver, kidney, stomach warp.Effect liver and kidney tonifying, bone and muscle strengthening, Chong and Ren Meridians regulating, solid through antiabortive.The lumbago and skelalgia or aching and limp unable that treatment insufficiency of kidney-YANG causes.Born of the same parents' tire that deficiency of liver-QI causes is not solid, the diseases such as scrotum pruritus due to damp pathogen.Shennong's Herbal is classified as top grade.
Herba Lycopodii, dehumidifying detumescence, relaxing muscles and tendons and activating QI and blood in the collateral.For anemofrigid-damp arthralgia, muscle arteries and veins contracture pain.External is controlled osteopatia sprain and is swollen and ache.
Radix Notoginseng, warm in nature, acrid in the mouth, has scattered silt hemostasis, effect of subduing swelling and relieving pain.
Radix Dipsaci, invigorating the liver and kidney, bone and muscle strengthening, continuous injured, only metrorrhagia.For: soreness of the waist and knees, rheumatic arthralgia, metrorrhagia, vaginal bleeding during pregnancy, injury from falling down.
Catechu, bitter, puckery, be slightly cold.Return lung meridian, have the drug effect of removing dampness promoting tissue regeneration and ulcer healing.For ulcer being unable to heal, eczema, aphtha, falls and flutters the pain of injury, traumatic hemorrhage.
Theory of Chinese medical science is thought: trauma fracture must cause meridians in body, vim and vigour and function disorderly, cause vim and vigour all to hinder, battalion defends internal organs discord, and meridians check, bone marrow, periosteum and surrounding tissue and blood fortune are destroyed, therefore, treatment should follow QI and blood regulating meridians, reducing swelling and alleviating pain, blood circulation promoting and blood stasis dispelling, dual-purpose tonifying QI to promote blood circulation, passage, nourishing blood simultaneously, thus reach blood circulation promoting and blood stasis dispelling, the object of quick reunion of fractured tendons and bones.
Compared with prior art, the invention has the beneficial effects as follows:
1, the present invention is natural plant, mineral drug, animal drugs combine, and its scientific formula, compatibility are reasonable, have no side effect and untoward reaction.
2, any artificial fixed form that do not need train wheel bridge, planter cast, burden to tie up etc., alleviates the misery of patient, also mitigates the financial burden of patient simultaneously.
3, short, the instant effect of healing stage of the present invention.Soon get final product obvious pain relieving after using this medicine, clinical practice proof can Shorten the Treatment Process compared with traditional therapy.
4, the present invention is on the basis of local method secret recipe, and improve through clinical practice again, cure rate is high.
Detailed description of the invention
The present invention is further detailed explanation now.
embodiment 1
A kind of alleviate pain and knit the fractured bone medical ointment plaster, comprise sticker sheet and be coated in the ointment on sticker sheet, described ointment is made primarily of the raw material of following parts by weight: Radix onosmatis 20 parts, Radix Angelicae Sinensis 30 parts, 10 parts, Rhizoma Zingiberis Recens, Herba Spilanthis callimorphae 12 parts, Ramulus Sambuci Williamsii 9 parts, Ramulus et Folium Tupidanthi celyptrati 5 parts, 8 parts, Rhizoma Curcumae Longae, the Cortex Eucommiae 30 parts, Herba Lycopodii 10 parts, Radix Notoginseng 9 parts, Radix Dipsaci 12 parts, 15 parts, catechu, vegetable oil 180 parts, 180 parts, vaseline, 220 parts, rice wine.
The preparation method of above-mentioned alleviate pain and knit the fractured bone medical ointment plaster, be crushed into powder after above-mentioned each raw material is dried, and mix homogeneously, then by furnishing paste in rear to above-mentioned mixed-powder and heating micro-cool vegetable oil, rice wine and vaseline, and then paste is coated on sticker sheet.
embodiment 2
A kind of alleviate pain and knit the fractured bone medical ointment plaster, comprise sticker sheet and be coated in the ointment on sticker sheet, described ointment is made primarily of the raw material of following parts by weight: Radix onosmatis 40 parts, Radix Angelicae Sinensis 60 parts, 20 parts, Rhizoma Zingiberis Recens, Herba Spilanthis callimorphae 30 parts, Ramulus Sambuci Williamsii 16 parts, Ramulus et Folium Tupidanthi celyptrati 10 parts, 20 parts, Rhizoma Curcumae Longae, the Cortex Eucommiae 50 parts, Herba Lycopodii 16 parts, Radix Notoginseng 25 parts, Radix Dipsaci 24 parts, 25 parts, catechu, vegetable oil 260 parts, 260 parts, vaseline, 350 parts, rice wine.
The preparation method of above-mentioned alleviate pain and knit the fractured bone medical ointment plaster, be crushed into powder after above-mentioned each raw material is dried, and mix homogeneously, then by furnishing paste in rear to above-mentioned mixed-powder and heating micro-cool vegetable oil, rice wine and vaseline, and then paste is coated on sticker sheet.
embodiment 3
A kind of alleviate pain and knit the fractured bone medical ointment plaster, comprise sticker sheet and be coated in the ointment on sticker sheet, described ointment is made primarily of the raw material of following parts by weight: Radix onosmatis 30 parts, Radix Angelicae Sinensis 50 parts, 15 parts, Rhizoma Zingiberis Recens, Herba Spilanthis callimorphae 20 parts, Ramulus Sambuci Williamsii 12 parts, Ramulus et Folium Tupidanthi celyptrati 8 parts, 15 parts, Rhizoma Curcumae Longae, the Cortex Eucommiae 40 parts, Herba Lycopodii 15 parts, Radix Notoginseng 18 parts, Radix Dipsaci 20 parts, 20 parts, catechu, vegetable oil 200 parts, 130 parts, vaseline, 300 parts, rice wine.
The preparation method of above-mentioned alleviate pain and knit the fractured bone medical ointment plaster, be crushed into powder after above-mentioned each raw material is dried, and mix homogeneously, then by furnishing paste in rear to above-mentioned mixed-powder and heating micro-cool vegetable oil, rice wine and vaseline, and then paste is coated on sticker sheet.
therapeutic outcome:
The present inventor and carry out clinical observation treatment to 697 routine out-patients so far in 2005, the age, from 3 years old to 90 years old etc. men and women's quantity was substantially inequal.
Therapeutic Method is: above-mentioned plaster is affixed on affected part, and a course for the treatment of is 2-3 days.
Efficacy assessment standard:
Cure: symptom and sign disappears completely;
Effective: symptom and sign comparatively before alleviates;
Invalid: symptom and sign is front without improving with treatment.
Therapeutic effect:
Case load 697
Cure number 689
Significant figure 8
Invalid number 0
Cure rate 98.8%
Total effective rate 100%
With above-mentioned according to desirable embodiment of the present invention for enlightenment, by above-mentioned description, relevant staff in the scope not departing from this invention technological thought, can carry out various change and amendment completely.The technical scope of this invention is not limited to the content in description, must determine its technical scope according to right.

Claims (7)

1. an alleviate pain and knit the fractured bone medical ointment plaster, comprises sticker sheet and is coated in the ointment on sticker sheet, it is characterized in that: described ointment is made primarily of the raw material of following parts by weight: Radix onosmatis 20-40 part, Radix Angelicae Sinensis 30-60 part, Rhizoma Zingiberis Recens 10-20 part, Herba Spilanthis callimorphae 12-30 part, Ramulus Sambuci Williamsii 9-16 part, Ramulus et Folium Tupidanthi celyptrati 5-10 part, Rhizoma Curcumae Longae 8-20 part, Cortex Eucommiae 30-50 part, Herba Lycopodii 10-16 part, Radix Notoginseng 9-25 part, Radix Dipsaci 12-24 part, catechu 15-25 part, oily 180-260 part, vaseline 180-260 part, wine 220-350 part.
2. alleviate pain and knit the fractured bone medical ointment plaster according to claim 1, is characterized in that: described ointment is made primarily of the raw material of following parts by weight: Radix onosmatis 20 parts, Radix Angelicae Sinensis 30 parts, 10 parts, Rhizoma Zingiberis Recens, Herba Spilanthis callimorphae 12 parts, Ramulus Sambuci Williamsii 9 parts, Ramulus et Folium Tupidanthi celyptrati 5 parts, 8 parts, Rhizoma Curcumae Longae, the Cortex Eucommiae 30 parts, Herba Lycopodii 10 parts, Radix Notoginseng 9 parts, Radix Dipsaci 12 parts, 15 parts, catechu, oil 180 parts, 180 parts, vaseline, wine 220 parts.
3. alleviate pain and knit the fractured bone medical ointment plaster according to claim 1, is characterized in that: described ointment is made primarily of the raw material of following parts by weight: Radix onosmatis 40 parts, Radix Angelicae Sinensis 60 parts, 20 parts, Rhizoma Zingiberis Recens, Herba Spilanthis callimorphae 30 parts, Ramulus Sambuci Williamsii 16 parts, Ramulus et Folium Tupidanthi celyptrati 10 parts, 20 parts, Rhizoma Curcumae Longae, the Cortex Eucommiae 50 parts, Herba Lycopodii 16 parts, Radix Notoginseng 25 parts, Radix Dipsaci 24 parts, 25 parts, catechu, oil 260 parts, 260 parts, vaseline, wine 350 parts.
4. alleviate pain and knit the fractured bone medical ointment plaster according to claim 1, is characterized in that: described ointment is made primarily of the raw material of following parts by weight: Radix onosmatis 30 parts, Radix Angelicae Sinensis 50 parts, 15 parts, Rhizoma Zingiberis Recens, Herba Spilanthis callimorphae 20 parts, Ramulus Sambuci Williamsii 12 parts, Ramulus et Folium Tupidanthi celyptrati 8 parts, 15 parts, Rhizoma Curcumae Longae, the Cortex Eucommiae 40 parts, Herba Lycopodii 15 parts, Radix Notoginseng 18 parts, Radix Dipsaci 20 parts, 20 parts, catechu, oil 200 parts, 130 parts, vaseline, wine 300 parts.
5. alleviate pain and knit the fractured bone medical ointment plaster according to claim 1, is characterized in that: described oil is vegetable oil.
6. alleviate pain and knit the fractured bone medical ointment plaster according to claim 1, is characterized in that: described wine is rice wine.
7. the preparation method of alleviate pain and knit the fractured bone medical ointment plaster according to claim 1, it is characterized in that: be crushed into powder after above-mentioned each raw material is dried, and mix homogeneously, then by furnishing paste in rear to above-mentioned mixed-powder and heating micro-cool oil, wine and vaseline, and then paste is coated on sticker sheet.
CN201410560434.7A 2014-10-21 2014-10-21 Analgesic bone ointment paste and preparation method thereof Pending CN104353024A (en)

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