CN104352988A - 一种治疗经前期紧张综合征的中药 - Google Patents

一种治疗经前期紧张综合征的中药 Download PDF

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CN104352988A
CN104352988A CN201410671775.1A CN201410671775A CN104352988A CN 104352988 A CN104352988 A CN 104352988A CN 201410671775 A CN201410671775 A CN 201410671775A CN 104352988 A CN104352988 A CN 104352988A
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premenstrual tension
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郑亚萍
刘春杰
董立珉
王兴红
蔡智慧
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Luohe Medical College
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Abstract

本发明属于中药技术领域，涉及一种治疗经前期紧张综合征的中药,它是由黄芪30-40份、党参30-40份、郁金15-20份、元胡10-15份、乌药10-15份、香附子13-17份、红花10-15份、鸡内金10-15份、生地15-20份、琥珀5-13份、龙骨8-13份、黄连15-20份、瓜蒌20-25份、川芎13-17份、赤芍14-12份、远志12-15份、女贞子17-25份、甘草10-15份。本发明是发明人在祖传秘方的基础上，结合自己多年临床经验的总结，经过反复实验而得，它采用多种中草药联合作用，综合施治，使药物的有效成份迅速渗透病灶，改善病变部，能快速治愈各种原因引起的经前期紧张综合征，而且见效快、疗程短、治愈率高、费用小。

Description

一种治疗经前期紧张综合征的中药
技术领域                                    
   本发明涉及一种中药，具体的说涉及一种治疗经前期紧张综合征的中药。
背景技术
经前期综合征是指妇女在月经周期的后期(黄体期D14-D28)表现出的一系列生理和情感方面的不适症状，主要表现有烦躁易怒、失眠、紧张、压抑以及头痛、乳房胀痛、颜面浮肿等一系列的症状，严重者可影响妇女的正常生活。经前期综合征与内分泌、代谢、经期心理等因素有关，肝气郁结是导致此病的重要因素。目前对该病临床多采用抗焦虑药、非选择性5-羟色胺重吸收抑制剂、激素、心理及手术治疗，但均存在效果不理想，副作用大、易复发的问题，而一些治疗本病的中草药，也起不到治疗效果。 
发明内容
本发明的目的是克服现有技术不足，而提供一种疗效快、费用低、无毒副作用、能快速治疗经前期紧张综合征的中药。 
为实现本发明的目的，现依据了如下的技术方案。该药是由以下重量份配比的原料制成： 
黄芪30-40份、党参30-40份、郁金15-20份、元胡10-15份、乌药10-15份、香附子13-17份、红花10-15份、鸡内金10-15份、生地15-20份、琥珀5-13份、龙骨8-13份、黄连15-20份、瓜蒌20-25份、川芎13-17份、赤芍14-12份、远志12-15份、女贞子17-25份、甘草10-15份。
本发明制备方法为：按组方称取上述各药，然后用粉碎机粉碎过120目筛，混合均匀，然后泛水为丸，即得本发明药物。 
本发明人认为：经前期综合征是是是育龄妇女发病率较高的疾病之一，其发病机制的研究开展不多，目前多认为可能由激素和其它如神经内分泌因素促发或对孕激素的高敏感性，也可能由5-羟色胺分泌不足造成。此外，社会心理因素对经前期综合征发生有一定的影响。临床采用的非选择性5-羟色胺重吸收抑制剂或雌激素等虽有一定的治疗作用，但是具有明显副作用，不宜长期服用，因而能够长期服用、副作用小、疗效佳的治疗方法成为当前的研究热点。 
研究调查也证实患者因压力大出现抑郁、焦虑、烦躁情绪，导致肝郁失疏、气血失和、冲任失调、肝郁化火，是出现此病诸多症状的重要原因。正如《丹溪心法》所云：“气血冲和，万病不生，一有拂郁，诸病生焉。”治宜疏肝理气，温阳利水，养阴平肝，养心健脾。 
具体实施方式
按下列比例称取原料： 
黄芪30-40份、党参30-40份、郁金15-20份、元胡10-15份、乌药10-15份、香附子13-17份、红花10-15份、鸡内金10-15份、生地15-20份、琥珀5-13份、龙骨8-13份、黄连15-20份、瓜蒌20-25份、川芎13-17份、赤芍14-12份、远志12-15份、女贞子17-25份、甘草10-15份。
本发明制备方法为：按组方称取上述各药，然后用粉碎机粉碎过120目筛，混合均匀，然后泛水为丸，即得本发明药物。 
服用方法: 服用方法:每日三次，饭后服用，每次6g，温开水送服，一般7天一个疗程，服药1-5疗程。 
本发明是发明人在祖传秘方的基础上，结合自己多年临床经验的总结，经过反复实验而得，它采用多种中草药联合作用，综合施治，使药物的有效成份迅速渗透病灶，改善病变部，能快速治愈各种原因引起的经前期紧张综合征，而且见效快、疗程短、治愈率高、费用小。 
为表明本发明的中药对经前期综合征的治疗效果，本发明人对240例病例进行临床观察。 
1.资料和方法 
1.1患者西医 PMS 诊断标准参照美国妇产科学会（ACOG）推荐的 PMS 国际诊断标准制定，中医肝气逆证诊断参考标准参照“中华人民共和国中医行业标准《中医病证诊断疗效标准》”和《中药新药治疗经前期紧张综合征的临床研究指导原则》制定。
自2012年1月—2014年1月期间选择来门诊就诊且符合符合西医 PMS 诊断标准及符合中医肝气逆证诊断参考标准的患者180例，年龄19-42岁，平均年龄32岁，病程1-7 年。排除患有乳腺增生与痛经为主症者；或妊娠或哺乳期妇女；或服用避孕药、激素类、维生素类及其它治疗经前期综合征药物者；或合并有心血管、肾脏和造血系统等严重原发性疾病,或精神疾病患者；或过敏体质者。采用随机的研究方法，根据就诊的先后顺序随机随机分为2组，治疗组100例；对照组80例。两组比较经统计学处理无显著性差异(P>0.05)，具有可比性。 
治疗前后均观察：①“经前期综合征中医症状评分表”各症状、体征及总分分值的变化；②治疗前后血清E2、P、PRL 及NE、5-HT 水平的变化。“症状变化打分表”各条目及总分及治疗前中后的比较。 
2.治疗方法 
治疗组：口服本发明中药，每日三次，饭后服用，每次6g，温开水送服。
对照组：口服杞菊地黄丸，一日两次，一次一丸。 
以上两组均以7天一个疗程，服药1-5疗程。 
2..结果 
疗效判定标准：临床疗效判定标准根据中华人民和国中医行业标准《中医病证诊断疗效标准制定》拟定：疗效指数：（N）= [（治疗前积分—治疗后积分）∕治疗前积分]*100％；痊愈：主要症状消失，次要症状大部分消失或明显减轻，N≥90％,停药3月经周期后随访无复发。显效：主要症状明显好转，次要症状部分消失或明显减轻，90％＞N≥66.67％，治疗结束后观察3个月症状未见加重。有效：主要症状得到控制，次要症状存在，66.67％＞N≥33.3％，治疗结束后部症状虽有反复，但较治疗前有所减轻。无效：中医证候无明显改善，N ﹤33.3％。
治疗组总有效率为96.0%，对照组为71.5%，经X2 检验，P<0.01，说明两组病例的中医证候总疗效比较有显著性差异，发明中药治疗经前期综合征的总疗效优于杞菊地黄丸。该发明具有创新先进、方法简易、实用性强、安全可靠等特点，因此具有较高的临床推广应用价值，具有良好的社会效益和经济效益。两组患者治疗前后疗效比较（表1） 
表2.1 两组患者疗效比较
组别 例数 痊愈 显效 有效 无效 总有效率（%）
治疗组 100 70 17 9 4 96.0
对照组 80 35 12 10 23 71.5
3.与国内外同类技术比较
本发明与国内外同类技术比较有如下特点：
1.客观性：本发明课题采用严格的实验设计要求，观察指标除选取“经前期综合征中医症状评分表”各症状、体征及总分分值外，还选取了治疗前后血清E2、P、PRL 及NE、5-HT 等客观指标，此点对研究结果的可靠及稳定性得以保障。
2.实用性：本课题以临床常见的经前期综合征为研究内容，研究结果显示本发明对其有明显治疗效果，今后经前期综合征治疗提供了有力支撑。 
3.先进、创新性：从肝气逆证入手研究经前期综合征，在病例选择及治疗指标的设定方面严格遵守科学准则，在研究本中药治疗经前期综合征效果同时还研究此药作用的可能机制，为中药开发及科学研究标准的制定有积极意义。 
4.系统性：课题从临床症状、发病机制及本发明的作用机制进行探讨，研究系统性强，目前国内外相关报道较少。 
基于以上几方面说明本发明处于国内同类研究的先进水平。 

Claims (2)

1.一种治疗经前期紧张综合征的中药,其特征在于它是由以下重量份配的原料制成：黄芪30-40份、党参30-40份、郁金15-20份、元胡10-15份、乌药10-15份、香附子13-17份、红花10-15份、鸡内金10-15份、生地15-20份、琥珀5-13份、龙骨8-13份、黄连15-20份、瓜蒌20-25份、川芎13-17份、赤芍14-12份、远志12-15份、女贞子17-25份、甘草10-15份。
2.根据权利要求1所述的一种治疗经前期紧张综合征的中药的制取方法，其特征在于：
按组方称取上述各药，然后用粉碎机粉碎过120目筛，混合均匀，然后泛水为丸，即得本发明药物。
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106890085A (zh) * 2017-01-23 2017-06-27 安徽绿莹彩龙艾绒制药有限公司 一种灸疗更年期综合症的药艾灸

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101361949A (zh) * 2008-09-18 2009-02-11 李爱英 一种治疗妇科月经病的中药
CN101391008A (zh) * 2008-10-15 2009-03-25 赵国华 一种治疗月经失调的中药丸剂
CN101837112A (zh) * 2010-06-30 2010-09-22 泰一和浦（北京）中医药研究院有限公司 一种治疗月经先后无定期的中药组合物及其制备方法
CN101966318A (zh) * 2010-07-12 2011-02-09 泰一和浦（北京）中医药研究院有限公司 一种治疗经行乳房胀痛的中药组合物及其制备方法
CN101966319A (zh) * 2010-07-12 2011-02-09 泰一和浦（北京）中医药研究院有限公司 一种治疗经行眩晕的中药组合物及其制备方法
CN102526635A (zh) * 2012-03-06 2012-07-04 钟美琴 一种治疗经前期紧张综合症的药物及其制备方法
CN104027745A (zh) * 2014-01-26 2014-09-10 赵永珍 一种用于治疗经前期紧张综合征的中药

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101361949A (zh) * 2008-09-18 2009-02-11 李爱英 一种治疗妇科月经病的中药
CN101391008A (zh) * 2008-10-15 2009-03-25 赵国华 一种治疗月经失调的中药丸剂
CN101837112A (zh) * 2010-06-30 2010-09-22 泰一和浦（北京）中医药研究院有限公司 一种治疗月经先后无定期的中药组合物及其制备方法
CN101966318A (zh) * 2010-07-12 2011-02-09 泰一和浦（北京）中医药研究院有限公司 一种治疗经行乳房胀痛的中药组合物及其制备方法
CN101966319A (zh) * 2010-07-12 2011-02-09 泰一和浦（北京）中医药研究院有限公司 一种治疗经行眩晕的中药组合物及其制备方法
CN102526635A (zh) * 2012-03-06 2012-07-04 钟美琴 一种治疗经前期紧张综合症的药物及其制备方法
CN104027745A (zh) * 2014-01-26 2014-09-10 赵永珍 一种用于治疗经前期紧张综合征的中药

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
叶艺玲: "女性经前期紧张综合征的辨证治疗", 《中国实用乡村医生杂志》 *
杨建武: "逍遥散在内科妇科的应用进展", 《云南中医学院学报》 *
梁香云: "中医治疗经前期紧张综合征60例临床疗效观察", 《云南中医中药杂志》 *
王菊素等: "田淑霄老师以脾论治月经病经验（二）", 《河北中医》 *
肖国士等: "《中医秘方全书（珍藏本）超值版》", 30 April 2012, 湖南科学技术出版社 *
霍清平: "调肝法在经前期紧张综合征中的应用", 《河南中医药学刊》 *
黎济民: "芪附四君汤治疗经前期紧张综合征50例", 《湖北中医杂志》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106890085A (zh) * 2017-01-23 2017-06-27 安徽绿莹彩龙艾绒制药有限公司 一种灸疗更年期综合症的药艾灸

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