CN104352728A - Traditional Chinese medicine preparation for treating fibroadenoma of mammary glands - Google Patents
Traditional Chinese medicine preparation for treating fibroadenoma of mammary glands Download PDFInfo
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- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/88—Liliopsida (monocotyledons)
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- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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Abstract
The invention discloses a traditional Chinese medicine preparation for treating fibroadenoma of mammary glands. The traditional Chinese medicine preparation is characterized by comprising the following raw herbal materials in parts by weight: 15 parts of codonopsis pilosula, 10 parts of rhizoma cyperi, 25 parts of fresh water kelp, 12 parts of pericarpium citri reticulatae viride, 12 parts of dried tangerine peel, 20 parts of complete trichosanthes kirilowii, 8 parts of radix bupleuri, 15 parts of prunella vulgaris, 15 parts of rohdea japonica and 8 parts of fingered citron. The medicines can be prepared into any ordinary oral preparations by using ordinary traditional Chinese medicine preparation methods, for example, the raw herbal materials can be grinded into powder and uniformly mixed to be prepared into powder which is taken with water and can be boiled with water and concentrated into decoction, or the concentrated decoction is concentrated into ointment and processed into pellets.
Description
Technical field
The present invention relates to field of traditional Chinese, be specifically related to a kind of Chinese medicine preparation being used for the treatment of mammary gland fibroma.There is effect of blood circulation promoting and blood stasis dispelling, hard masses softening and resolving, heat-clearing and toxic substances removing, treatment mammary gland fibroma determined curative effect.
Background technology
Mammary gland fibroadenoma betides fibrous tissue and epithelioglandular Combination tumor in lobules of mammary gland, is modal one in excision of benign breast.Mammary gland fibroadenoma can betide the women at postpubertal any age, and the generation of primary disease is lacked of proper care relevant with endocrine hormone, as estrogen relatively or definitely raises and can cause primary disease.Producing reason is that in lobule, fibrocyte increases estrogenic sensitivity is abnormal, may be relevant with the exception of the amount of estrogen receptor contained by fibrocyte or matter.Estrogen is this pathogenetic stimulating factor, so fibroadenoma betides the ovarian function phase.Can be divided into three types clinically: 1. plain edition fibroadenoma: this kind of is the most common, tumor body is little, poor growth, generally below 3 centimetres.2. hebephrenictype fibroadenoma: mostly occur in the menarche phase, clinical more rare, feature is very fast for growing, and tumor body is comparatively large, and the course of disease can take full milk room at about 1 year, lump maximum diameter is 1 ~ 13 centimetre.3. Giant fibroadenomas: middle-aged women is common, is found in women before and after gestation, suckling, amenorrhea, and feature grows comparatively greatly, can reach more than 10 centimetres or larger, occasionally can have sarcomatous change.
Summary of the invention
The Chinese medicine preparation for the treatment of mammary gland fibroma of the present invention, has effect of nourshing blood and promoting blood circulation, nourishing the liver and kidney, treatment mammary gland fibroma determined curative effect.
The raw medicinal material selected and components by weight percent be respectively: Radix Codonopsis 15 parts, Rhizoma Cyperi 10 parts, light Thallus Laminariae (Thallus Eckloniae) 25 parts, 12 parts, Pericarpium Citri Reticulatae Viride, Pericarpium Citri Reticulatae 12 parts, Fructus Trichosanthis 20 parts, Radix Bupleuri 8 parts, Spica Prunellae 15 parts, Rohdea japonica Roth 15 parts, Fructus Citri Sarcodactylis 8 parts.
In the raw materials of traditional Chinese medicinal materials that the present invention chooses, its effect and pharmacological action respectively: Radix Codonopsis: there is invigorating the spleen and replenishing QI, effect of spleen invigorating lung benefiting.For deficiency of the spleen and lung, cardiopalmus of breathing hard, anorexia and loose stool, dyspnea due to deficiency is coughed, and interior-heat is quenched one's thirst.Meridian distribution of property and flavor: property is put down, sweet in the mouth, micro-acid.Return spleen, lung meridian.Chemical composition: Radix Codonopsis is containing triterpenoid compound freidelin (friedelin), alnulin acetas, bessisterol and glycoside thereof, Δ 7-stigmastenol and glycoside, spinach sterone (spinesterone).Another containing atractylenoide Ⅲ (atractylenolide III), atractyloide II (atractylenolide II), syringic aldehyde (syringaldehyde), Syringin (syringin), vanillic acid (vanillic acid), 5-hydroxyl-2-piconol (5-hydroxy-2-pyridinemethanol), α-furyl carboxylic acid (α-furancarboxylic acid), n-hexyl-glycoside (n-hexyl-β-D-glucopyranoside), ethyl-α-D-fructofuranoside (ethyl-α-D-fructofuranoside), and nicotinic acid, 4 kinds of heteropolysaccharide and monosaccharide etc.Still containing tangshenoside I, codonolactone and codopiloic acid.Modern study, Radix Codonopsis, containing various saccharides, phenols, sterol, volatile oil, scutellarein glucosid, Saponin and Alkaloid, has enhancing immunity, blood vessel dilating, blood pressure lowering, improves microcirculation, strengthens the effects such as hemopoietic function.In addition castering action is had to the leukopenia that chemotherapy radiotherapy causes.
Rhizoma Cyperi: the dry rhizome of sedge dried tuber.To regulate the flow of vital energy resolving depression; Menstruction regulating and pain relieving; Antiabortive.Main distending pain over the hypochondrium; Mammary swelling is educated; Hernia pain; Menoxenia; Gastral cavity abdomen feeling of fullness pain; Belch acid regurgitation, vomiting and nausea; Abdominal pain during menstruation; Bleeding not during menses; Frequent fetal movement.For stagnation of QI due to depression of the liver, breast, the side of body, abdominal distention, dyspepsia, breast gastral cavity painful abdominal mass is vexed, and colic of cold type is suffered from abdominal pain, distending pain of the breast, menoxenia, amenorrhea dysmenorrhea.
Light Thallus Laminariae (Thallus Eckloniae): [nature and flavor, return through] are salty-cold, enter liver, stomach, kidney channel.[function] eliminating phlegm and softening indurated mass, inducing diuresis to remove edema.For goiter scrofula, the diseases such as edema.
Pericarpium Citri Reticulatae Viride: the distending pain over the hypochondrium of main stagnation of QI due to depression of the liver; Distending pain of the breast; Nodule in the breast; Acute mastitis; Hernia pain; The epigastric distending pain of stagnation of QI due to dyspepsia; And qi depression to blood stasis lump in the abdomen extremely; Chronic malaria addiction block.[nature and flavor, return through] toil, temperature.Enter liver, gallbladder, stomach warp.[function] is soothing the liver dispelling the stagnated QI, removing food stagnancyization are stagnant.
Pericarpium Citri Reticulatae: Pericarpium Citri Reticulatae contains hesperidin about 8.4%, Nobiletin (nobiletin) about 0.15%. separately containing Neosynephrine (oxedrine) 0.28%-2.54％。[nature and flavor] are bitter, pungent, temperature.[return through] returns lung, spleen channel.[attending effectiveness]: regulating qi-flowing for strengthening spleen, in tune, dampness, reduces phlegm.Cure mainly distension and fullness in the abdomen or pain, the dyspepsia of stagnation of QI in spleen and stomach.Abdominal distention uncomfortable in chest in turbid damp resistance, indigestion and loss of appetite loose stool.Phlegm-damp stops up the cough and asthma of lung.For fullness in the epigastrium and chest, lack of appetite and vomiting, cough with copious phlegm.
Fructus Trichosanthis: chemical composition: containing triterpenoid saponin, organic acid and its esters, resin, saccharide, arginine, lysine, alanine, valine, isoleucine, leucine, glycine and Alkaloid material, pigment etc.; Function cures mainly: clearing away heat and eliminating phlegm, and relieving stuffiness of the chest by dispersing aggregation of pathogens moisturizes laxation.For cough due to lung-heat, the turbid Huang of expectorant is thick, obstruction of qi in the chest and cardialgia, blocked-up chest feeling of fullness, acute mastitis, lung abscess, and acute appendicitis swells and ache, constipation.
Radix Bupleuri: clearind deficient heat Chinese medicine, comes off for cold, fever, alternate attack of chill and fever, malaria, stagnation of QI due to depression of the liver, sternal rib pain, proctoptosis, uterus, menoxenia.Meridian distribution of property and flavor: cold nature, bitter in the mouth, pungent, return Liver Channel, lung meridian, spleen channel.Function: expelling pathogenic factors from the exterior expels the heat-evil, dispersing the stagnated live-QI to relieve the stagnation of QI, elevate a turnable ladder yang-energy.Cure mainly: cold, fever, alternate attack of chill and fever, malaria, stagnation of QI due to depression of the liver, sternal rib pain, proctoptosis, uterus comes off, menoxenia.
Spica Prunellae: [meridian distribution of property and flavor]: cold; Bitter, pungent; Return liver, gallbladder meridian.[function cures mainly]: relieve inflammation or internal heat, improving eyesight, eliminating stagnation, detumescence.For conjunctival congestion and swelling pain, order pearl nyctalgia, has a headache dizzy, scrofula, and goiter, swells and ache; Thyromegaly, tuberculous lymphadenitis, cyclomastopathy, hypertension, hyperglycemia, hyperlipidemia and high blood viscosity.
Rohdea japonica Roth: Gui Jing: bitter, micro-sweet, cold.Slightly poisonous.Effect: heat-clearing and toxic substances removing, heart tonifying diuresis.Cure mainly: for preventing and treating diphtheria, the myocarditis that diphtheria causes, laryngopharynx swelling and pain, bacillary dysentery, Cardiac Failure From Rheumatic Heart Disease; Traumatic injury is controlled in external, venom, burn and scald, mastitis, carbuncle furuncle and phyma poison.
Fructus Citri Sarcodactylis: meridian distribution of property and flavor: pungent, bitter, sour, temperature.Return liver, spleen, stomach, lung meridian.Function cures mainly: liver-smoothing, qi-regulating, and stomach and alleviating pain, drying dampness to eliminate phlegm.For stagnation of liver-QI and stomach-QI, distending pain in the chest and hypochondrium, gastral cavilty feeling of fullness, lack of appetite is vomitted, cough with copious phlegm.
Complementary with the raw medicinal material property of medicine effect selected by top, evade the choosing of the mutual inhibition of compatibility between medicine, mutual restraint between two drugs, the mutual-detoxication, making medicine mutual reinforcement between, mutual-assistance effect significantly, have the effect of blood circulation promoting and blood stasis dispelling, hard masses softening and resolving, heat-clearing and toxic substances removing, is for oral administration pure Chinese herbal medicine composition preparation for the treatment of mammary gland fibroma.
Medicine of the present invention can adopt the conventional method of Chinese medicine preparation to be prepared into any conventional oral preparations.Such as these crude drug pulverize mix homogeneously powder can be taken after mixing it with water; Can by these crude drug together decocting, then concentrated decocting liquid is taken, or concentrated decocting liquid is condensed into cream is processed into pill and takes; In order to make each raw material of this medicine play drug effect better, carry out special extraction for certain crude drug, as ethanol extraction, these can not be used for limiting the scope of the invention.Active component of the present invention can add various customary adjuvant required when preparing different dosage form, peroral dosage form is commonly used, as pill, powder, tablet, capsule, oral liquid etc. as disintegrating agent, lubricant, binding agent etc. are prepared into any one with the method for Chinese medicinal of routine.
Medicine of the present invention has effect of blood circulation promoting and blood stasis dispelling, hard masses softening and resolving, heat-clearing and toxic substances removing, is used for the treatment of mammary gland fibroma.The present inventor through repeatedly studying, and passes through the checking repeatedly of clinical trial, finally have found the endo-medicine of better curative effect, thus completes the present invention.Clinical practice has good precise effects:
The basic document of clinical practice and model case:
Embodiment 1. Lee XX, female, 42 years old.First visit on July 10 in 2009.
Patient before 1 year the left breast of self-induction swell, dull pain is uncomfortable, but does not mind.In in July, 2009 exacerbation of symptoms, go to a doctor at certain hospital surgery, be diagnosed as left adenofibroma of breast, suggestion surgical resection therapy.I does not agree to operation, and the department of Chinese medicine of coming is gone to a doctor.Defecation is logical adjusts, and body of the tongue is normal, stringy pulse.This belongs to liver energy depression and phlegm stagnation and becomes nodules of the breast.Should depressed liver-energy dispersing and QI regulating dissipating phlegm and resolving masses.After clothes we 30 doses, transference cure, recovers.
Method and effective dose: Radix Codonopsis 15 parts, Rhizoma Cyperi 10 parts, light Thallus Laminariae (Thallus Eckloniae) 25 parts, 12 parts, Pericarpium Citri Reticulatae Viride, Pericarpium Citri Reticulatae 12 parts, Fructus Trichosanthis 20 parts, Radix Bupleuri 8 parts, Spica Prunellae 15 parts, Rohdea japonica Roth 15 parts, Fructus Citri Sarcodactylis 8 parts; Get prescription ormal weight tcm and herbal slice, put in suitable decocting device, add clear water appropriate, soak suitable time, be heated to boil, keep slight boiling condition certain hour (about 25 ~ 30 minutes), be separated fried liquid, medicinal residues add water and decoct in right amount, after regulation decoction 2 ~ 3 times, merge fried liquid, filter or settlement separate fried liquid for.
Decoction oral is main, and every day takes orally for 2 times sooner or later, each 150ml decoction being taken warmly.Decoction then acts on fast and power is high, is adapted to the more anxious severe one of the state of an illness.As lighter in the state of an illness or slow person, is preferably that pill is for oral administration asks its merit
Detailed description of the invention
Treatment mammary gland fibroma Chinese medicine preparation, the raw medicinal material selected and components by weight percent respectively: Radix Codonopsis 15 parts, Rhizoma Cyperi 10 parts, light Thallus Laminariae (Thallus Eckloniae) 25 parts, 12 parts, Pericarpium Citri Reticulatae Viride, Pericarpium Citri Reticulatae 12 parts, Fructus Trichosanthis 20 parts, Radix Bupleuri 8 parts, Spica Prunellae 15 parts, Rohdea japonica Roth 15 parts, Fructus Citri Sarcodactylis 8 parts.
Medicine of the present invention can adopt the conventional method of Chinese medicine preparation to be prepared into any conventional oral preparations.Such as these crude drug pulverize mix homogeneously powder can be taken after mixing it with water; Can by these crude drug together decocting, then concentrated decocting liquid is taken, or concentrated decocting liquid is condensed into cream is processed into pill and takes.
Claims (1)
1. treat the Chinese medicine preparation of mammary gland fibroma for one kind, it is characterized in that, the raw medicinal material selected and components by weight percent respectively: Radix Codonopsis 15 parts, Rhizoma Cyperi 10 parts, light Thallus Laminariae (Thallus Eckloniae) 25 parts, 12 parts, Pericarpium Citri Reticulatae Viride, Pericarpium Citri Reticulatae 12 parts, Fructus Trichosanthis 20 parts, Radix Bupleuri 8 parts, Spica Prunellae 15 parts, Rohdea japonica Roth 15 parts, Fructus Citri Sarcodactylis 8 parts;
Preparation method: get Radix Codonopsis 15 parts, Rhizoma Cyperi 10 parts, light Thallus Laminariae (Thallus Eckloniae) 25 parts, 12 parts, Pericarpium Citri Reticulatae Viride, Pericarpium Citri Reticulatae 12 parts, Fructus Trichosanthis 20 parts, Radix Bupleuri 8 parts, Spica Prunellae 15 parts, Rohdea japonica Roth 15 parts, Fructus Citri Sarcodactylis 8 parts; Ormal weight tcm and herbal slice, put in suitable decocting device, add clear water appropriate, soak suitable time, be heated to boil, keep slight boiling condition certain hour (about 25 ~ 30 minutes), be separated fried liquid, medicinal residues add water and decoct in right amount, after regulation decoction 2 ~ 3 times, merge fried liquid, filter or settlement separate fried liquid for.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104887896A (en) * | 2015-06-19 | 2015-09-09 | 圣原健康产业有限公司 | Massage cream and traditional Chinese medicine composition for cyclomastopathy treatment and preparation method of massage cream and traditional Chinese medicine composition for cyclomastopathy treatment |
| CN105687593A (en) * | 2016-03-18 | 2016-06-22 | 刘健楠 | Traditional Chinese medicine composition for treating mammary gland fibroma |
| CN109985224A (en) * | 2019-04-25 | 2019-07-09 | 刘玥 | A kind of formula for mammary gland patient symptom |
-
2014
- 2014-10-27 CN CN201410608854.8A patent/CN104352728A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104887896A (en) * | 2015-06-19 | 2015-09-09 | 圣原健康产业有限公司 | Massage cream and traditional Chinese medicine composition for cyclomastopathy treatment and preparation method of massage cream and traditional Chinese medicine composition for cyclomastopathy treatment |
| CN104887896B (en) * | 2015-06-19 | 2018-11-30 | 圣原健康产业有限公司 | Chinese medicine composition and the massage cream and preparation method thereof for treating cyclomastopathy |
| CN105687593A (en) * | 2016-03-18 | 2016-06-22 | 刘健楠 | Traditional Chinese medicine composition for treating mammary gland fibroma |
| CN109985224A (en) * | 2019-04-25 | 2019-07-09 | 刘玥 | A kind of formula for mammary gland patient symptom |
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