CN104352589A - 一种以人参为主要原料的中药戒烟液及其制备方法 - Google Patents
一种以人参为主要原料的中药戒烟液及其制备方法 Download PDFInfo
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- CN104352589A CN104352589A CN201410524434.1A CN201410524434A CN104352589A CN 104352589 A CN104352589 A CN 104352589A CN 201410524434 A CN201410524434 A CN 201410524434A CN 104352589 A CN104352589 A CN 104352589A
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Abstract
本发明公开了一种以人参为主要原料的中药戒烟液,主要由以下重量份的原料制成:人参14~26份、甘草8~15份、酸枣仁5~9份、肉豆蔻4~8份、茯苓2~4份。本发明还公开了该中药戒烟液的制备方法。本发明戒烟液具有戒烟效果好、安全无毒、携带和使用方便等优点。
Description
技术领域
本发明涉及一种戒烟液,尤其涉及一种以人参为主要原料的中药戒烟液。本发明还涉及该中药戒烟液的制备方法。
背景技术
科学研究证实,香烟燃烧时,会释放3800多种有毒有害物质,包括焦油、尼古丁、一氧化碳、氰化物、邻甲酚和苯酚等。焦油及烟雾通过口腔后,使唾液腺发炎,味蕾受损,容易引发口腔癌。当烟雾通过喉部,使咽喉的温度上升到 42℃,粘膜烧伤,喉咙发痒,易引发喉癌。烟雾进入肺部后,破坏气道绒毛,粘液分泌增加,使肺部发生病变,人就经常咳嗽,胸闷气短。同时,烟草中的多种放射线同位素会留存在肺、肾、胰、性腺等器官和骨髓中,使正常细胞转化成癌细胞,造成多个器官癌变。包括口腔癌、食道癌、喉癌、肺癌、胆囊癌等等。
吸烟有害健康是尽人皆知的道理,我国的烟民总和将近3.5亿。《AC尼尔森烟草市场调查报告》统计得出:有一半以上的吸烟者心存戒烟的想法,17%的烟民迫切希望戒烟。按照这种算法,中国大概有6000万人迫切需要解除对香烟的依赖,而2.5亿人对戒烟存在需求。吸烟容易戒烟难。当烟民戒烟时,体内尼古丁浓度降低,人会产生焦虑不安、烦躁、压抑、注意力不集中等戒烟综合症状,从而使戒烟难度加大。
目前市场上的戒烟产品较多,包括电子烟、戒烟贴、戒烟牙膏、戒烟药以及一些中草药或植物提取的戒烟液。但是这些产品目前仍然未能达到理想的戒烟效果,有些甚至起不到戒烟作用。
发明内容
本发明的第一个目的在于提供一种戒烟效果好、安全无毒、携带和使用方便、不易复吸的以人参为主要原料的中药戒烟液。
本发明的第二个目的在于提供上述戒烟液的制备方法。
本发明的第一个目的是通过以下技术方案来实现的:一种以人参为主要原料的中药戒烟液,其主要由以下重量份的原料制成:人参14~26份、甘草8~15份、酸枣仁5~9份、肉豆蔻4~8份、茯苓2~4份。
本发明选用人参、甘草、酸枣仁、肉豆蔻、和茯苓为主方制成戒烟液进行人体戒烟试验,并筛选出有效的配比。其中,人参归脾、肺经、心经,具有大补元气、复脉固脱、补脾益肺、生津止渴、安神益智的综合功效,有利于平衡戒烟者的戒烟综合症,舒缓不吸烟时的焦虑情绪,并能调整因吸烟引起的血压上升,使人恢复心肺功能;另外,人参有祛痰功效,能够减缓吸烟者的痰多症状,恢复肺部功能。甘草和中缓急,能调和诸药,具有养血安神,清热除烦之功,可使阴血得补、心神得养、虚热得清,虚烦不眠、心悸等症可除,有效缓解吸烟者戒烟时的心理焦燥情绪,并缓解吸烟者的咽喉肿痛、气喘咳嗽等症状。肉豆蔻归脾、胃、大肠经,具有行气消食的功效,肉豆蔻挥发油中所含的甲基异丁香酚有抑制中枢神经作用,能有效减缓不吸烟时的兴奋传导,使人降低吸烟欲望。酸枣仁归心、肝经,具有养肝血,宁心安神的功效,可减少戒烟时的心神不宁、躁动不安现象,有效缓解戒断综合症。茯苓味甘、淡、性平,归心、脾、肾经,入药具有利水渗湿、益脾和胃、宁心安神之功用。可以减少戒烟时的心神不宁、躁动不安现象,有效缓解戒断综合症。综合使用上述药物,使得各药物功效产生协同作用,从而使吸烟者安定精神、舒缓神经紧张、缓和失眠症,使吸烟者在刚戒烟时能度过焦躁不安的过渡期。
进一步地,上述原料的配比优选为:人参18~24份、甘草9~12份、酸枣仁6~8份、肉豆蔻6~8份、茯苓3~4份。
本发明可做以下改进,在所述主方中增加以下重量份的原料:佛手2~5份、知母2~4份、鱼腥草2~4份、干姜2~4.5份、桔梗2~4.5份。
佛手无毒,味辛、苦、甘;性温;入肝、脾、胃三经,有理气化痰、止呕消胀、舒肝健脾、和胃更多种药用功能。对因吸烟而引起的气管炎、哮喘病有明显的缓解作用;同时对戒烟后容易产生的消化不良、胸腹胀闷,有更为显著的疗效。鱼腥草味辛,性寒凉,归肺经。能清热解毒、消肿疗疮、利尿除湿、清热止痢、健胃消食,现代药理实验表明,鱼腥草的有效成分癸酰乙醛有抑菌作用,鱼腥草的挥发油中含抗菌成分鱼腥草素,具有抗菌、抗病毒作用。配合甘草,能够对吸烟者的呼吸道感染有治疗作用。干姜味辛,性热。归脾、胃、心、肺经,具有温中散寒,回阳通脉,燥湿消痰,温肺化饮等功效,可以帮助吸烟者解决多年吸烟后形成的咳嗽痰多、胸闷不畅、咽痛、音哑等症状。知母性苦寒质润,滋阴清热,用于肺热咳嗽或阴虚燥咳、痰稠等证。桔梗具有宣肺,利咽,祛痰,排脓的功能。用于治疗咳嗽痰多,胸闷不畅,咽痛,音哑,肺痈吐脓,疮疡脓成不溃。在所述主方中增加上述药物,有助于改善吸烟者出现的鼻咽喉等病变。
进一步地,上述原料的配比优选为:佛手3~4份、知母2~3份、鱼腥草2~3份、干姜3~4份、桔梗2.5~4份。
本发明还可做以下改进,在所述主方或者上述改进方中分别增加以下重量份的原料:砂仁3~7份,优选为4~6份。
砂仁性温,味辛,主要作用于人体的胃、肾和脾,能够行气调味、和胃醒脾、下气止痛、宽胸膈、疏气滞、除呕逆、增食欲、止冷泻、开胃、化滞、消食的功效,可有效解决吸烟者戒烟后的食欲不振。
本发明还可做进一步改进,在所述主方或者上述改进方中分别增加以下重量份的原料:薄荷2~5份、冰片2~4份。
薄荷,疏风散寒、辟秽、解毒。冰片气清香,味辛、凉,带挥发性,易升华,能使药液快速被人体吸入。
上述诸药成分的协同作用,在嗅入过程中,使人产生一种愉悦、放松感,并缓解吸烟者戒烟时的焦虚、心神不安、注意力不集中、精神紧张等戒断综合症状,减轻吸烟者对香烟的渴望,可使吸烟者平和度过戒烟期,同时可有效改善吸烟者的咽喉肿痛、咽干、口苦痰多、气喘咳嗽等问题,有利于恢复吸烟者因吸烟而受损的心肺功能。另外,由于嗅入本复方药液,当吸烟者再次吸烟时,可使人产生对烟草气味的厌恶感,从而对吸烟失去兴趣,并开始逐步减少香烟的吸入量,吸烟者体内尼古丁浓度自然地逐步下降,机体开始适应,尼古丁依赖感减少,心理和生理逐渐摆脱对香烟的依赖,直至最终成功戒烟。
本发明的第二个目的是通过以下技术方案来实现的:上述戒烟液的制备方法,其包括以下步骤:
1)按重量配比称取前述的戒烟液原料,粉碎,过筛;
2)粉碎后的原料加8~15倍水煎煮提取两次,每次提取2~5h,合并两次提取液,过滤、浓缩得浓缩液,第一次煎煮时同时回收原料的挥发成分;
3)将步骤2)所得浓缩液在90℃~100℃温度下浓缩成密度为1.15-1.20克/毫升的浸膏;
4)浸膏中加入乙醇进行醇沉,边加边搅拌,静置,取上清液,回收乙醇,所得溶液与步骤1)中回收的挥发成分混合均匀,即可作为戒烟液。
以下是本发明推荐的实施方式:
所述步骤1)中原料粉碎成20~60目的颗粒。
所述步骤2)中粉碎后的原料加水煎煮提取时,第一次加水8~12倍量;第二次加水8~10倍量。
所述步骤4)中所采用的乙醇为90%~95%的乙醇;乙醇的使用量为:添加至滤液中乙醇浓度为75%~80%。
当本发明还包括佛手、知母、鱼腥草、干姜和桔梗时,步骤1)为:按重量配比称取人参、甘草、酸枣仁、肉豆蔻、茯苓、佛手、知母、鱼腥草、干姜和桔梗,粉碎,过筛。
当本发明还包括砂仁时,步骤1)为:按重量配比称取人参、甘草、酸枣仁、肉豆蔻、茯苓、佛手、知母、鱼腥草、干姜、桔梗和砂仁,粉碎,过筛。
当本发明还包括薄荷和冰皮时,步骤1)为:按重量配比称取人参、甘草、酸枣仁、肉豆蔻、茯苓、佛手、知母、鱼腥草、干姜、桔梗、砂仁和薄荷,粉碎,过筛;还包括步骤5):冰片溶于乙醇,加入与步骤1)中回收的挥发成分混合均匀,然后与所述步骤4)的上清液充分混合,静置2h,滤过,得澄清溶液,分装。
所述步骤5)中,冰片溶于四倍量的75%乙醇中。
本发明的使用方法:想吸烟时打开戒烟液的瓶盖,将瓶口距鼻部约1cm处,用深呼吸的方法进行吸闻,鼻吸口呼,每次闻3~5分钟,也可闻5~10分钟,一天一次或多次,连续使用三天;对于烟瘾大、烟龄长的人,可使用一周或更长的时间。
本发明具有下述优点:
(1) 戒烟方法简单,戒烟效果好
依本发明制备的戒烟液,如实施例1,经对109人的有效征集试验证实,连续使用15天的戒烟总有效率达到95.41%,戒烟成功6个月后的复吸率仅为11.54%。
说明:下表的戒烟状况指使用本发明药液15天后的戒烟状况;复吸情况指成功戒烟6个月后的复吸情况。
以下举例来说明本发明的功效:
(2) 安全无毒副作用
本发明所选取的原料组份均为选自于国家卫生部的《药食同源原料目录》或保健食品原料,产品无毒副作用,安全可靠。同时由于采用吸闻方式,不会产生成瘾性。
(3) 携带和使用方便:
本发明戒烟液可装在3~5ml的瓶子里,携带方便,想吸烟时,打开瓶盖,通过鼻吸口呼,一天一次或几次,一般使用3天即可有效控制烟瘾,轻微烟瘾的烟民可以很快戒烟,严重者则需要使用更长一点的时间戒除烟瘾。一般情况下,使用本戒烟药液,多数烟民可在10-15天内达到戒烟的效果。
(4) 本发明含有多种清热解毒的药物,对鼻炎的治疗也有一定的效果。
具体实施方式
以下结合实施例对本发明进行阐述,然而本发明的保护范围并非仅仅局限于以下实施例。所属技术领域的普通技术人员依据本发明公开的内容,均可实现本发明的目的。
实施例一:
原料:人参140份、甘草80份、酸枣仁50份、肉豆蔻40份、佛手20份、知母20份、茯苓20份、薄荷20份、鱼腥草20份、砂仁30份、桔梗20份、干姜20份、冰片20份。
制备方法:
1) 按重量配比称取人参、甘草、酸枣仁、肉豆蔻、佛手、知母、茯苓、薄荷、鱼腥草、砂仁、桔梗和干姜,粉碎成20目的颗粒,过筛。
2) 粉碎后的原料加10倍水煎煮提取两次,每次提取4h,合并两次提取液,过滤、浓缩得浓缩液;第一次煎煮时同时回收挥发成分。
3) 将步骤2)所得浓缩液在95℃温度下浓缩成密度为1.15克/毫升的浸膏。
4) 浸膏中加入93%乙醇,使含醇达到75%进行醇沉,边加边搅拌,然后冷却静置48小时,取上清液,回收乙醇。对回收液重复醇沉2次,合并上清液。
5) 用四倍量75%乙醇与冰片混合,令冰片完全溶解在乙醇中,加入步骤1)中回收的挥发成分,混合,将所得液体与第4)步所得上清液充分混合,静置2h,滤过,得澄清溶液,分装。
为使本发明药液适合于多种吸烟者嗅闻,可按1﹕100的比例加入不同香味的食用香精,从而形成多种气味的戒烟液体。
实施例二:
原料:人参220份、甘草100份、酸枣仁70份、肉豆蔻50份、佛手30份、知母30份、茯苓30份、薄荷30份、鱼腥草30份、砂仁60份、桔梗30份、干姜30份、冰片20份。
制备方法:
1) 按重量配比称取人参、甘草、酸枣仁、肉豆蔻、佛手、知母、茯苓、薄荷、鱼腥草、砂仁、桔梗和干姜,粉碎成60目的颗粒,过筛。
2) 粉碎后的原料加10倍水煎煮提取两次,每次提取4h,合并两次提取液,过滤、浓缩得浓缩液;第一次煎煮时同时回收挥发成分。
3) 将步骤2)所得浓缩液在100℃温度下浓缩成密度为1.20克/毫升的浸膏。
4) 浸膏中加入95%乙醇,使含醇达到80%进行醇沉,边加边搅拌,然后冷却静置48小时,取上清液,回收乙醇。对回收液重复醇沉2次,合并上清液。
5) 用四倍量75%乙醇与冰片混合,令冰片完全溶解在乙醇中,加入步骤1)中回收的挥发成分,混合,将所得液体与第4)步所得上清液充分混合,静置2h,滤过,得澄清溶液,分装。
为使本发明药液适合于多种吸烟者嗅闻,可按1﹕100的比例加入不同香味的食用香精,从而形成多种气味的戒烟液体。
实施例三:
人参260份、甘草150份、酸枣仁90份、肉豆蔻80份、佛手50份、知母40份、茯苓40份、薄荷50份、鱼腥草40份、砂仁70份、桔梗45份、干姜45份、冰片40份。
制备方法:
1) 按重量配比称取人参、甘草、酸枣仁、肉豆蔻、佛手、知母、茯苓、薄荷、鱼腥草、砂仁、桔梗和干姜,粉碎成40目的颗粒,过筛。
2) 粉碎后的原料加10倍水煎煮提取两次,每次提取4h,合并两次提取液,过滤、浓缩得浓缩液;第一次煎煮时同时回收挥发成分。
3) 将步骤2)所得浓缩液在90℃℃温度下浓缩成密度为1.18克/毫升的浸膏。
4) 浸膏中加入95%乙醇,使含醇达到75%进行醇沉,边加边搅拌,然后冷却静置48小时,取上清液,回收乙醇,剩余溶液重复醇沉2次,合并上清液。
5) 用四倍量75%乙醇与冰片混合,令冰片完全溶解在乙醇中,加入步骤1)中回收的挥发成分,混合,将所得液体与第4)步所得上清液充分混合,静置2h,滤过,得澄清溶液,分装。
为使本发明药液适合于多种吸烟者嗅闻,可按1﹕100的比例加入不同香味的食用香精,从而形成多种气味的戒烟液体。
实施例四:
人参240份、甘草90份、酸枣仁80份、肉豆蔻80份、佛手30份、知母25份、茯苓30份、薄荷40份、鱼腥草25份、桔梗30份、干姜30份、冰片40份。
制备方法:
1) 按重量配比称取人参、甘草、酸枣仁、肉豆蔻、佛手、知母、茯苓、薄荷、鱼腥草、桔梗和干姜,粉碎成40目的颗粒,过筛。
2) 粉碎后的原料加10倍水煎煮提取两次,每次提取4h,合并两次提取液,过滤、浓缩得浓缩液;第一次煎煮时同时回收挥发成分。
3) 将步骤2)所得浓缩液在95℃温度下浓缩成密度为1.17克/毫升的浸膏。
4) 浸膏中加入93%乙醇,使含醇达到75%进行醇沉,边加边搅拌,然后冷却静置48小时,取上清液,回收乙醇,剩余溶液重复醇沉2次,合并上清液。
5) 用四倍量75%乙醇与冰片混合,令冰片完全溶解在乙醇中,加入步骤1)中回收的挥发成分,混合,将所得液体与第4)步所得上清液充分混合,静置2h,滤过,得澄清溶液,分装。
为使本发明药液适合于多种吸烟者嗅闻,可按1﹕100的比例加入不同香味的食用香精,从而形成多种气味的戒烟液体。
实施例五:
人参180份、甘草90份、酸枣仁60份、肉豆蔻70份、佛手30份、知母20份、茯苓30份、薄荷50份、鱼腥草20份、砂仁50份、桔梗30份、干姜30份、冰片40份。
制备方法:
1) 按重量配比称取人参、甘草、酸枣仁、肉豆蔻、佛手、知母、茯苓、薄荷、鱼腥草、桔梗、和干姜,粉碎成30目的颗粒,过筛。
2) 粉碎后的原料加10倍水煎煮提取两次,每次提取4h,合并两次提取液,过滤、浓缩得浓缩液;第一次煎煮时同时回收挥发成分。
3) 将步骤2)所得浓缩液在95℃温度下浓缩成密度为1.20克/毫升的浸膏。
4) 浸膏中加入90%乙醇,使含醇达到75%进行醇沉,边加边搅拌,然后冷却静置48小时,取上清液,回收乙醇,剩余溶液重复醇沉2次,合并上清液。
5) 用四倍量75%乙醇与冰片混合,令冰片完全溶解在乙醇中,加入步骤1)中回收的挥发成分,混合,将所得液体与第4)步所得上清液充分混合,静置2h,滤过,得澄清溶液,分装。
为使本发明药液适合于多种吸烟者嗅闻,可按1﹕100的比例加入不同香味的食用香精,从而形成多种气味的戒烟液体。
实施例六:
人参180g、甘草80g、酸枣仁50g、茯苓40g、肉豆蔻70g、佛手30g、知母20g、鱼腥草30g、干姜30份、桔梗30g、薄荷50份、砂仁50g、冰片40g。
制备方法:
1) 按重量配比称取人参、甘草、酸枣仁、肉豆蔻、佛手、知母、茯苓、鱼腥草、桔梗、干姜、砂仁和薄荷,粉碎成50目的颗粒,过筛。
2) 粉碎后的原料加10倍水煎煮提取两次,每次提取4h,合并两次提取液,过滤、浓缩得浓缩液;第一次煎煮时同时回收挥发成分。
3) 将步骤2)所得浓缩液在100℃温度下浓缩成密度为1.19克/毫升的浸膏。
4) 浸膏中加入93%乙醇,使含醇达到78%进行醇沉,边加边搅拌,然后冷却静置48小时,取上清液,回收乙醇,剩余溶液重复醇沉2次,合并上清液。
5) 用四倍量75%乙醇与冰片混合,令冰片完全溶解在乙醇中,加入步骤1)中回收的挥发成分,混合,将所得液体与第4)步所得上清液充分混合,静置2h,滤过,得澄清溶液,分装。
为使本发明药液适合于多种吸烟者嗅闻,可按1﹕100的比例加入不同香味的食用香精,从而形成多种气味的戒烟液体。
实施例七:
人参230g、甘草120g、酸枣仁80g、茯苓35g、肉豆蔻60g、佛手35g、知母25g、鱼腥草25g、干姜35份、桔梗35g、砂仁40g。
制备方法:
1) 按重量配比称取人参、甘草、酸枣仁、肉豆蔻、佛手、知母、茯苓、鱼腥草、桔梗、干姜和砂仁,粉碎成50目的颗粒,过筛。
2) 粉碎后的原料加10倍水煎煮提取两次,每次提取4h,合并两次提取液,过滤、浓缩得浓缩液;第一次煎煮时同时回收挥发成分。
3) 将步骤2)所得浓缩液在100℃温度下浓缩成密度为1.15克/毫升的浸膏。
4) 浸膏中加入93%乙醇,使含醇达到75%进行醇沉,边加边搅拌,然后冷却静置48小时,取上清液,回收乙醇,剩余溶液重复醇沉2次,合并上清液。
5) 步骤1)中回收的挥发成分与第4)步所得上清液充分混合,静置2h,滤过,得澄清溶液,分装。
为使本发明药液适合于多种吸烟者嗅闻,可按1﹕100的比例加入不同香味的食用香精,从而形成多种气味的戒烟液体。
实施例八:
人参150g、甘草90g、酸枣仁65g、茯苓40g、肉豆蔻75g、佛手30g、知母25g、鱼腥草30g、干姜30份、桔梗30g。
制备方法:
1) 按重量配比称取人参、甘草、酸枣仁、肉豆蔻、佛手、知母、茯苓、鱼腥草、桔梗和干姜,粉碎成50目的颗粒,过筛。
2) 粉碎后的原料加10倍水煎煮提取两次,每次提取4h,合并两次提取液,过滤、浓缩得浓缩液;第一次煎煮时同时回收挥发成分。
3) 将步骤2)所得浓缩液在100℃温度下浓缩成密度为1.16克/毫升的浸膏。
4) 浸膏中加入95%乙醇,使含醇达到75%进行醇沉,边加边搅拌,然后冷却静置48小时,取上清液,回收乙醇,剩余溶液重复醇沉2次,合并上清液。
5) 步骤1)中回收的挥发成分与第4)步所得上清液充分混合,静置2h,滤过,得澄清溶液,分装。
为使本发明药液适合于多种吸烟者嗅闻,可按1﹕100的比例加入不同香味的食用香精,从而形成多种气味的戒烟液体。
Claims (10)
1.一种以人参为主要原料的中药戒烟液,其特征在于,主要由以下重量份的原料制成:人参14~26份、甘草8~15份、酸枣仁5~9份、肉豆蔻4~8份、茯苓2~4份。
2.根据权利要求1所述的以人参为主要原料的中药戒烟液,其特征在于,人参18~24份、甘草9~12份、酸枣仁6~8份、肉豆蔻6~8份、茯苓3~4份。
3.根据权利要求1或2所述的以人参为主要原料的中药戒烟液,其特征在于,还包括以下重量份的原料:佛手2~5份、知母2~4份、鱼腥草2~4份、干姜2~4.5份、桔梗2~4.5份。
4.根据权利要求3所述的以人参为主要原料的中药戒烟液,其特征在于,佛手3~4份、知母2~3份、鱼腥草2~3份、干姜3~4份、桔梗2.5~4份。
5.根据权利要求1或2或3或4所述的以人参为主要原料的中药戒烟液,其特征在于,还包括以下重量份的原料:砂仁3~7份。
6.根据权利要求5所述的以人参为主要原料的中药戒烟液,其特征在于,还包括以下重量份的原料:薄荷2~5份、冰片2~4份。
7.根据权利要求1或2或3或4所述的以人参为主要原料的中药戒烟液,其特征在于,还包括以下重量份的原料:薄荷2~5份、冰片2~4份。
8.权利要求1~7任一项所述的以人参为主要原料的中药戒烟液的制备方法,其特征在于,其包括以下步骤:
1)按重量配比称取前述的戒烟液原料,粉碎,过筛;
2)粉碎后的原料加8~15倍水煎煮提取两次,每次提取2~5h,合并两次提取液,过滤、浓缩得浓缩液,第一次煎煮时同时回收原料的挥发成分;
3)将步骤2)所得浓缩液在90℃~100℃温度下浓缩成密度为1.15-1.20克/毫升的浸膏;
4)浸膏中加入乙醇进行醇沉,边加边搅拌,静置,取上清液,回收乙醇,所得溶液与步骤1)中回收的挥发成分混合均匀,即可作为戒烟液。
9.权利要求8所述的以人参为主要原料的中药戒烟液的制备方法,其特征在于,所述步骤2)中粉碎后的原料加水煎煮提取时,第一次加水8~12倍量;第二次加水8~10倍量;所述步骤4)中所采用的乙醇为90%~95%的乙醇;乙醇的使用量为:添加至滤液中乙醇浓度为75%~80%。
10.权利要求8或9所述的以人参为主要原料的中药戒烟液的制备方法,其特征在于,还包括步骤5):冰片溶于乙醇,加入与步骤1)中回收的挥发成分混合均匀,然后与所述步骤4)的上清液充分混合,静置2h,滤过,得澄清溶液,分装;所述步骤5)中,冰片溶于四倍量的75%乙醇中。
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