CN104352561A - Radix achyranthis bidentatae-containing traditional Chinese medicine composition for lowering blood pressure - Google Patents
Radix achyranthis bidentatae-containing traditional Chinese medicine composition for lowering blood pressure Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/618—Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/21—Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/482—Cassia, e.g. golden shower tree
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/536—Prunella or Brunella (selfheal)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/537—Salvia (sage)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
Abstract
The invention discloses a radix achyranthis bidentatae-containing traditional Chinese medicine composition for lowering blood pressure and belongs to the technical field of medicines. The radix achyranthis bidentatae-containing traditional Chinese medicine composition for lowering blood pressure, disclosed by the invention, is prepared from the following medicinal raw materials in parts by weight: 5-20 parts of oenothera biennis, 3-10 parts of cassia seed, 3-10 parts of nacre, 3-10 parts of radix achyranthis bidentatae, 5-15 parts of azalea sprout, 3-10 parts of salvia miltiorrhiza, 1-5 parts of selfheal spike and 1-5 parts of beartiful sweetgum fruit. According to the traditional Chinese medicine composition for lowering blood pressure, disclosed by the invention, after the 8 kinds of medicinal raw materials are combined according to a proportioning ratio, the traditional Chinese medicine composition has a synergistic function and is remarkable in treatment effect when the traditional Chinese medicine composition is used for treating hypertension, and obvious side effects and adverse reactions are not discovered.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, be specifically related to a kind of blood pressure lowering Chinese medicine composition containing Radix Achyranthis Bidentatae, belong to medical art.
Background technology
Hypertension increases clinical syndrome for main manifestations with systemic arterial pressure, is modal cardiovascular disease.Hypertension can be divided into constitutional and the large class of Secondary cases two.In most patient, hypertensive etiology unknown, is referred to as essential hypertension, accounts for total hyperpietic's more than 95%; Less than in 5% patient, it is a kind of clinical manifestation of some disease that blood pressure raises, and itself has clearly and the independently cause of disease, is called secondary hypertension.Essential hypertension, also known as hypertension, usual onset is slow, often asymptomatic in early days, for many years conscious well even discovery blood pressure rising when physical examination, and small number of patients then just can be found after the complication such as the generation heart, brain, kidney.
Hypertension incidence is high, can bring out the generation of the disease such as coronary heart disease, cerebral hemorrhage, and great majority cause a series of damage of the vitals such as the heart, brain, kidney and serious pathological changes, or even nonfunction, and sugared, eagle matter metabolism disorder, very large threat is caused to the healthy of people.According to statistics, whole world Prevalence of Hypertension, up to 10%-20%, is suffered from hypertensive number and is reached 1,000,000,000, dies from per year over l200 ten thousand people the various diseases that hypertension causes.Population of China Prevalence of Hypertension is in rising trend, three national hypertension investigation displays.The sickness rate of l959 is 5.11%.L979-1980 annual morbidity is 7.73%, l990-1991 annual morbidity is 11.26%, and the existing hyperpietic of China has exceeded l.2 hundred million people, and annual still with the speed increase of more than 600 ten thousand people.According to World Health Organization's prediction, to the year two thousand twenty, noninfectious will account for 79% of China's cause of death.Wherein the cardiovascular disease such as hypertension will account for first place.Therefore, prevention and therapy hypertension has become the focus of society research; It is one of significant problem urgently to be resolved hurrily at present.
Hypertension is a kind of chronic disease needing long-term monitoring and treatment, needs to take medicine throughout one's life.Existing Altace Ramipril is generally Western medicine, and Long-term taking medicine can have larger side effect to the liver of human body, kidney etc., and easily causes the uncomfortable reaction such as cough, edema, dizziness.Therefore, be necessary to find a kind of little to health side effect, low-cost effective hypotensor.
Summary of the invention
To the object of the invention is to overcome in prior art existing above-mentioned deficiency, a kind of blood pressure lowering Chinese medicine composition is provided, this Chinese medicine composition low price, little to patient body side effect for blood pressure lowering good effect.
In order to realize foregoing invention object, the invention provides following technical scheme:
Containing a blood pressure lowering Chinese medicine composition for Radix Achyranthis Bidentatae, it is prepared from by the medicinal raw material of following weight proportion: Radix Oenotherae erythrosepalae 5 ~ 20 parts, Semen Cassiae 3 ~ 10 parts, Concha Margaritifera 3 ~ 10 parts, Radix Achyranthis Bidentatae 3 ~ 10 parts, DUMENGYA 5 ~ 15 parts, Radix Salviae Miltiorrhizae 3 ~ 10 parts, Spica Prunellae 1 ~ 5 part, Fructus Liquidambaris 1 ~ 5 part.Described various medicinal raw material is the Chinese crude drug meeting country or provincial standard and specify.
Preferably, in above-mentioned medicinal raw material proportioning, part by weight shared by Radix Oenotherae erythrosepalae is 9 ~ 15 parts.Preferred, part by weight shared by Radix Oenotherae erythrosepalae is 12 parts.
Preferably, in above-mentioned medicinal raw material proportioning, part by weight shared by Semen Cassiae is 5 ~ 8 parts.Preferred, part by weight shared by Semen Cassiae is 6 parts.
Preferably, in above-mentioned medicinal raw material proportioning, part by weight shared by Concha Margaritifera is 5 ~ 8 parts.Preferred, part by weight shared by Concha Margaritifera is 6 parts.
Preferably, in above-mentioned medicinal raw material proportioning, part by weight shared by Radix Achyranthis Bidentatae is 5 ~ 8 parts.Preferred, part by weight shared by Radix Achyranthis Bidentatae is 6 parts.
Preferably, in above-mentioned medicinal raw material proportioning, part by weight shared by DUMENGYA is 7 ~ 12 parts.Preferred, part by weight shared by DUMENGYA is 9 parts.
Preferably, in above-mentioned medicinal raw material proportioning, part by weight shared by Radix Salviae Miltiorrhizae is 5 ~ 8 parts.Preferred, part by weight shared by Radix Salviae Miltiorrhizae is 6 parts.
Preferably, in above-mentioned medicinal raw material proportioning, part by weight shared by Spica Prunellae is 2 ~ 4 parts.Preferred, part by weight shared by Spica Prunellae is 3 parts.
Preferably, in above-mentioned medicinal raw material proportioning, part by weight shared by Fructus Liquidambaris is 2 ~ 4 parts.Preferred, part by weight shared by Fructus Liquidambaris is 3 parts.
The present invention is used for the Chinese medicine composition of blood pressure lowering, the active component of medicinal raw material can be extracted according to extracting method conventional on Chinese materia medica, add pharmaceutically acceptable carrier or/and adjuvant, as starch, dextrin, microcrystalline cellulose, amylum pregelatinisatum, magnesium stearate, micropowder silica gel, sucrose, carboxymethyl starch sodium, hydroxypropyl emthylcellulose, vegetable oil, lecithin, Polyethylene Glycol, propylene glycol, ethyl hydroxybenzoate etc., make dosage form suitable on pharmaceutics, as granule, tablet, hard capsule, oral liquid, soft capsule, drop pill, water pill etc.
The extracting method of Chinese medicine composition of the present invention can adopt but be not limited to following methods:
(1) get each medicinal raw material by formula proportion, in medicinal raw material, add 60 ~ 80% ethanol or the water of medicinal raw material volume 8 ~ 10 times; Reflux, extract, 2 ~ 3 times; Extraction time is respectively 1 ~ 2h; Collect merge extractive liquid, and extracting solution is condensed into extractum, dry, obtain the extract of medicinal raw material of the present invention.
(2) in above-mentioned extract, add pharmaceutic adjuvant and be mixed and made into acceptable various pharmaceutical dosage form on pharmaceutics.
According to the needs of the various drug form of preparation, medicine of the present invention also can add suitable pharmaceutic adjuvant as filler, disintegrating agent, binding agent, lubricant, antiseptic etc. in preparation process.
Compared with prior art, beneficial effect of the present invention:
The present invention be used for blood pressure lowering Chinese medicine composition, be inventor based on motherland's medical science to hypertensive pathogenetic understanding, according to oneself clinical experience for many years, first determine a series of to the effective Chinese medicine of blood pressure lowering from numerous Chinese medicine, repeatedly verify through clinical again, screen.Wherein, Radix Oenotherae erythrosepalae, another name Radix Oenotherae erythrosepalae; Oenotheraceae Radix Oenotherae erythrosepalae, is used as medicine with root; Sweet, temperature; There is bone and muscle strengthening, effect of expelling wind and removing dampness; Mainly curing rheumatism, the diseases such as bones and muscles pain.Semen Cassiae, another name Horse hoof Semen Cassiae, blunt leaf Semen Cassiae, false Semen phaseoli radiati, Semen Cassiae; For the dry mature seed of leguminous plant Semen Cassiae or little Semen Cassiae; Sweet, bitter, salty, be slightly cold; Return liver, large intestine channel; There is clearing away heat to improve acuity of vision, effect of loosening bowel to relieve constipation; For the puckery pain of conjunctival congestion, the many tear of photophobia, the diseases such as dizzy, poor vision, constipation of having a headache.Concha Margaritifera, another name natural pearls are female, jewel is female; For the shell of Unionidae animal hydriopsis cumingii, cristaria plicata or Pteriidae animal Pteria martensii Dunker; Salty in the mouth, cold in nature; Return liver, heart channel; There is suppressing the hyperactive liver and subsiding YANG, effect of arresting convulsion improving eyesight; Dizzy for having a headache, irritated insomnia, liver-heat conjunctival congestion, the diseases such as deficiency of the liver blurred vision.Radix Achyranthis Bidentatae, another name Radix Achyranthis Bidentatae, cattle condyle knee joint, Herba Ophiorrhizae pumilae, Twotooth Achyranthes Root, Red Radix Achyranthis Bidentatae, Du's Radix Achyranthis Bidentatae; For the dry root of amaranthaceous plant Radix Achyranthis Bidentatae; Bitter in the mouth, acid, property is put down; Return liver, kidney channel; There is invigorating the liver and kidney, bone and muscle strengthening, eliminating blood stasis and inducing menstruation, effect of conducting blood to flow downwards; For soreness of waist and knee joint, muscles and bones is unable, amenorrhea lump in the abdomen, the diseases such as dizziness due to hyperactivity of liver-YANG.Radix Salviae Miltiorrhizae, another name Arisaema balansae Engl., Radix Campylotropis Hirtella (Herba Myrsines Africanae), Herba Wedeliae Wallichii root, blood mountain root, RADIX SALVIAE MILTIORRHIZAE, Radix Salviae Miltiorrhizae; For the dry root and rhizome of labiate Radix Salviae Miltiorrhizae; Hardship, is slightly cold; GUIXIN, Liver Channel; There is effect of stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, the relieving restlessness that clears away heart-fire; Swell and ache for menoxenia, amenorrhea dysmenorrhea, lump in the abdomen, breast ventral spine pain, pyretic arthralgia pain, skin infection, dysphoria and insomnia, hepatosplenomegaly, the disease such as angina pectoris.Spica Prunellae, another name wooden club grass, ferrum color grass, large headdress flower, summer withered head; For the dry fruit ear of labiate Spica Prunellae; Pungent, bitter, cold; Return liver, gallbladder meridian; Have and relieve inflammation or internal heat, improving eyesight, eliminating stagnation, effect of detumescence; For conjunctival congestion and swelling pain, order pearl nyctalgia, has a headache dizzy, scrofula, goiter, and acute mastitis swells and ache; Thyromegaly, tuberculous lymphadenitis, cyclomastopathy, the diseases such as hypertension.Fructus Liquidambaris, another name Fructus Liquidambaris; For the drying and ripening infructescence of Hamamelidaceae Plants Chinese sweet gum; Hardship, flat; Return liver, kidney channel; There is dispelling, collateral-activating, effect that diuretic stimulates the menstrual flow; For arthralgia, numbness contracture, edema distension, the diseases such as the few amenorrhea of breast.Above-mentioned 8 taste Chinese herbal medicine, flavour of a drug are few but function is complete, 8 taste medicinal raw materials are by after described proportioning combination, for blood pressure lowering, there is Synergistic function, experimental study shows, Chinese medicine composition of the present invention is used for blood pressure lowering instant effect, good effect, and administration is after one week, can to take effect and evident in efficacy, and not occur obvious adverse reaction during patient consumes.
Detailed description of the invention
Below in conjunction with test example and detailed description of the invention, the present invention is described in further detail.But this should be interpreted as that the scope of the above-mentioned theme of the present invention is only limitted to following embodiment, all technology realized based on content of the present invention all belong to scope of the present invention.
In embodiments of the invention and comparative example, ethanol used is the aqueous solution of ethanol, and the percentage composition of ethanol, if no special instructions, is volumn concentration.
Embodiment 1
The present embodiment is used for the Chinese medicine composition of blood pressure lowering, is be prepared from by the medicinal raw material of following weight proportion: Radix Oenotherae erythrosepalae 12g, Semen Cassiae 6g, Concha Margaritifera 6g, Radix Achyranthis Bidentatae 6g, DUMENGYA 9g, Radix Salviae Miltiorrhizae 6g, Spica Prunellae 3g, Fructus Liquidambaris 3g.
The extracting method of above-mentioned medicinal raw material:
(1) get each medicinal raw material by formula proportion, in medicinal raw material, add 60 ~ 80% ethanol or the water of medicinal raw material volume 8 ~ 10 times; Reflux, extract, 2 ~ 3 times; Extraction time is respectively 1 ~ 2h; Collect merge extractive liquid, and extracting solution is condensed into extractum, dry, obtain the extract of the medicinal raw material of embodiment 1.
(2) in above-mentioned extract, add the soluble starch of extract weight 2 times of weight, granulate, dry, be distributed into bag, obtain granule.
Embodiment 2
The present embodiment is used for the Chinese medicine composition of blood pressure lowering, is be prepared from by the medicinal raw material of following weight proportion: Radix Oenotherae erythrosepalae 20g, Semen Cassiae 10g, Concha Margaritifera 3g, Radix Achyranthis Bidentatae 3g, DUMENGYA 5g, Radix Salviae Miltiorrhizae 10g, Spica Prunellae 1g, Fructus Liquidambaris 5g.
The above-mentioned medicinal raw material of the present embodiment for the preparation of the method for the Chinese medicine composition of blood pressure lowering with embodiment 1.
Embodiment 3
The present embodiment is used for the Chinese medicine composition of blood pressure lowering, is be prepared from by the medicinal raw material of following weight proportion: Radix Oenotherae erythrosepalae 13g, Semen Cassiae 8g, Concha Margaritifera 7g, Radix Achyranthis Bidentatae 5g, DUMENGYA 12g, Radix Salviae Miltiorrhizae 8g, Spica Prunellae 2g, Fructus Liquidambaris 4g.
The above-mentioned medicinal raw material of the present embodiment for the preparation of the method for the Chinese medicine composition of blood pressure lowering with embodiment 1.
Comparative example
This comparative example is used for the Chinese medicine composition of blood pressure lowering, is be prepared from by the medicinal raw material of following weight proportion: Radix Oenotherae erythrosepalae 12g, Semen Cassiae 6g, Concha Margaritifera 6g, DUMENGYA 9g, Radix Salviae Miltiorrhizae 6g, Spica Prunellae 3g, Fructus Liquidambaris 3g.
The above-mentioned medicinal raw material of this comparative example for the preparation of the method for the Chinese medicine composition of blood pressure lowering with embodiment 1.
Pharmacodynamics and toxicity test:
In order to the efficacy and saferry of proved invention medicine, inventors performed pharmacodynamics and toxicity test investigation.The research method adopted and result of the test as follows:
1, test objective: the present invention is used for the Chinese medicine composition of blood pressure lowering to the hypotensive activity of original hypertensive rat.
2, test material
(1) medicine and reagent:
According to the Chinese medicine composition (making oral liquid) of embodiment 1 prepared by embodiment 1;
According to the Chinese medicine composition of comparative example prepared by comparative example, (making oral liquid);
Nifedipine Tablets: HARBIN PHARMACEUTICAL GROUP CO., LTD. General Pharm. Factory, (making oral liquid).
(2) animal: choose the original hypertensive rat 40 purchased from the laboratory animal department of the Chinese Academy of Sciences of Huaxi Medical Univ, body weight is 200 ~ 250g; Raise in positive pressure purification ventilation Animal House, room temperature 25 ± 2 DEG C, ad lib and drinking-water.
3, test method and result
Pretreatment before test: tested rat is put into measuring cell and carries out training 2 weeks, and blood pressure is measured second week rises the next day.The electrocaloric effect that before pressure measurement, animal puts into 37 ± 1 DEG C is heated, and measures rat systolic pressure after 15 minutes with RBP-1 type rat blood pressure instrument (Institute of Basic Medical Sciences of China-Japan Friendship Hospital, Beijing).
Process of the test: original hypertensive rat is divided into 4 groups at random, drug study group of the present invention, matched group 1, positive controls and model control group, often organize 10.The Chinese medicine composition oral liquid (7g raw medicinal herbs/kg, 1.5mL/50g) that the oral embodiment of the present invention of drug study group of the present invention 1 is obtained; The Chinese medicine composition oral liquid (7g raw medicinal herbs/kg, 1.5mL/50g) that the oral comparative example of the present invention of matched group 1 is obtained; Positive controls oral nifedipine sheet oral liquid (10mg/kg); The oral same volume distilled water of model control group, once a day, continuous 5 weeks.During administration and the ingesting of the mice respectively organized of fore-and-aft observing, movable and excretion situation situation all without exception occur.After administration the 1st, 2,3,4,5 weekends, measure the systolic pressure of rat, to measure 3 times at every turn, average.The blood pressure determination time after administration carries out after 2 hours in administration, and has measured in 4 hours upon administration.
Result of the test:
Adopt SPSS software to carry out statistical analysis, result of the test all represents with x ± s, and many group means compare employing ANOVA variance analysis, compare and check with q between group; There is significant P≤0.05 for difference.Result of the test is as shown in table 1, and table 1 was depicted as administration after 1 week, continuous 5 measurement statistical results to original hypertensive rat systolic pressure (unit: mmHg).
Table 1
Note: compare with model group:
*p<0.05; Compare with matched group 1:
▲ ▲p<0.05.
Experimental data in table 1 shows: the original hypertensive rat taking Chinese medicine composition oral liquid prepared by the embodiment of the present invention 1, administration is after 1 week, blood pressure starts to decline, continuously to the 4th weekend only, blood pressure is down to and is similar to normal value and substantially equal with the pressure value of positive controls; About 46mmHg is reduced relative to the rat blood pressure shrinkage value of model control group, and the Exemplary statistical data relative model matched group P<0.05 of medicine group of the present invention, there is significant difference.The present invention is used for the Chinese medicine composition of blood pressure lowering, for blood pressure lowering instant effect, good effect.
And matched group 1 shown in table 1 records rat blood pressure shrinkage value, after administration, blood pressure drops speed is slower.And administration is after 3 weeks, rat blood pressure shrinkage value still at about 120mmHg, and has no further decline.Chinese medicine composition for blood pressure lowering prepared by comparative example of the present invention, blood pressure lowering effect is poor; And the rat blood pressure shrinkage value statistical data of drug study group of the present invention is relative to the rat blood pressure shrinkage value statistical data P < 0.05 of matched group 1, has significant difference.Learn thus, the present invention is used for 8 kinds of medicinal raw materials of blood pressure lowering by after described weight proportion combination, and have Synergistic function, can significantly improve the curative effect of Chinese medicine composition, lack any component, the curative effect of Chinese medicine composition all significantly declines.
In sum, the present invention is containing the Chinese medicine composition for blood pressure lowering of Radix Achyranthis Bidentatae, and for hyperpietic's blood pressure lowering short treating period, instant effect, administration can take effect and evident in efficacy for 1 week.8 kinds of medicinal raw materials, by after described weight proportion combination, have Synergistic function, can significantly improve the hypertensive curative effect of traditional Chinese medicine composition for treating; Lack any component, its curative effect all significantly declines, therapeutic effect as matched group 1 significantly reduces relative to the therapeutic effect of drug study group of the present invention, and blood pressure lowering traditional Chinese medicine composition for treating hypertension of the present invention is little to patient body side effect, is applicable to hyperpietic's long-term taking.
Claims (10)
1., containing a blood pressure lowering Chinese medicine composition for Radix Achyranthis Bidentatae, it is characterized in that: it is prepared from by the medicinal raw material of following weight proportion: Radix Oenotherae erythrosepalae 5 ~ 20 parts, Semen Cassiae 3 ~ 10 parts, Concha Margaritifera 3 ~ 10 parts, Radix Achyranthis Bidentatae 3 ~ 10 parts, DUMENGYA 5 ~ 15 parts, Radix Salviae Miltiorrhizae 3 ~ 10 parts, Spica Prunellae 1 ~ 5 part, Fructus Liquidambaris 1 ~ 5 part.
2. blood pressure lowering Chinese medicine composition according to claim 1, is characterized in that: part by weight shared by Radix Oenotherae erythrosepalae is 9 ~ 15 parts.
3. blood pressure lowering Chinese medicine composition according to claim 2, is characterized in that: part by weight shared by Radix Oenotherae erythrosepalae is 12 parts.
4. blood pressure lowering Chinese medicine composition according to claim 1, is characterized in that: part by weight shared by Semen Cassiae is 5 ~ 8 parts.
5. blood pressure lowering Chinese medicine composition according to claim 1, is characterized in that: part by weight shared by Concha Margaritifera is 5 ~ 8 parts.
6. blood pressure lowering Chinese medicine composition according to claim 1, is characterized in that: part by weight shared by Radix Achyranthis Bidentatae is 5 ~ 8 parts.
7. blood pressure lowering Chinese medicine composition according to claim 1, is characterized in that: part by weight shared by DUMENGYA is 7 ~ 12 parts.
8. blood pressure lowering Chinese medicine composition according to claim 1, is characterized in that: part by weight shared by Radix Salviae Miltiorrhizae is 5 ~ 8 parts.
9. blood pressure lowering Chinese medicine composition according to claim 1, is characterized in that: part by weight shared by Spica Prunellae is 2 ~ 4 parts.
10. blood pressure lowering Chinese medicine composition according to claim 1, is characterized in that: part by weight shared by Fructus Liquidambaris is 2 ~ 4 parts.
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| CN106265908A (en) * | 2016-08-31 | 2017-01-04 | 榆林市普惠酒业集团有限公司 | A kind of blood pressure reducing medicated wine and production method thereof |
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| 中国社区医师编辑部: "柴浩然治疗高血压经验", 《中国社区医师》 * |
| 何群: "《不要乱吃药》", 31 January 1997 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106265908A (en) * | 2016-08-31 | 2017-01-04 | 榆林市普惠酒业集团有限公司 | A kind of blood pressure reducing medicated wine and production method thereof |
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