CN104435814A - Traditional Chinese medicine composition containing cyclocarya paliurus and having function of reducing blood pressure - Google Patents
Traditional Chinese medicine composition containing cyclocarya paliurus and having function of reducing blood pressure Download PDFInfo
- Publication number
- CN104435814A CN104435814A CN201410631835.7A CN201410631835A CN104435814A CN 104435814 A CN104435814 A CN 104435814A CN 201410631835 A CN201410631835 A CN 201410631835A CN 104435814 A CN104435814 A CN 104435814A
- Authority
- CN
- China
- Prior art keywords
- blood pressure
- chinese medicine
- parts
- medicine composition
- cyclocarya paliurus
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/482—Cassia, e.g. golden shower tree
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/52—Juglandaceae (Walnut family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
- A61K36/725—Ziziphus, e.g. jujube
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Alternative & Traditional Medicine (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a traditional Chinese medicine composition containing cyclocarya paliurus and having a function of reducing blood pressure, belonging to the technical field of medicines. The traditional Chinese medicine composition containing cyclocarya paliurus and having a function of reducing blood pressure is prepared from the following raw medicinal materials in parts by weight: 5-20 parts of tartary buckwheat, 5-12 parts of sea-buckthorn, 3-10 parts of cyclocarya paliurus, 3-10 parts of spina date seeds, 1-5 parts of corn stigma and 1-5 parts of semen cassia. According to the traditional Chinese medicine composition containing cyclocarya paliurus and having a function of reducing blood pressure disclosed by the invention, six medicinal raw materials are combined in proportion to take a synergic function and therefore the traditional Chinese medicine composition has a remarkable curative effect on hypertension and is free of obvious side effects and adverse reactions.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, be specifically related to a kind of blood pressure lowering Chinese medicine composition containing Cyclocarya paliurus Iljinskaja, belong to medical art.
Background technology
Hypertension increases clinical syndrome for main manifestations with systemic arterial pressure, is modal cardiovascular disease.Hypertension can be divided into constitutional and the large class of Secondary cases two.In most patient, hypertensive etiology unknown, is referred to as essential hypertension, accounts for total hyperpietic's more than 95%; Less than in 5% patient, it is a kind of clinical manifestation of some disease that blood pressure raises, and itself has clearly and the independently cause of disease, is called secondary hypertension.Essential hypertension, also known as hypertension, usual onset is slow, often asymptomatic in early days, for many years conscious well even discovery blood pressure rising when physical examination, and small number of patients then just can be found after the complication such as the generation heart, brain, kidney.
Hypertension incidence is high, can bring out the generation of the disease such as coronary heart disease, cerebral hemorrhage, and great majority cause a series of damage of the vitals such as the heart, brain, kidney and serious pathological changes, or even nonfunction, and sugared, eagle matter metabolism disorder, very large threat is caused to the healthy of people.According to statistics, whole world Prevalence of Hypertension, up to 10%-20%, is suffered from hypertensive number and is reached 1,000,000,000, dies from per year over l200 ten thousand people the various diseases that hypertension causes.Population of China Prevalence of Hypertension is in rising trend, three national hypertension investigation displays.The sickness rate of l959 is 5.11%.L979-1980 annual morbidity is 7.73%, l990-1991 annual morbidity is 11.26%, and the existing hyperpietic of China has exceeded l.2 hundred million people, and annual still with the speed increase of more than 600 ten thousand people.According to World Health Organization's prediction, to the year two thousand twenty, noninfectious will account for 79% of China's cause of death.Wherein the cardiovascular disease such as hypertension will account for first place.Therefore, prevention and therapy hypertension has become the focus of society research; It is one of significant problem urgently to be resolved hurrily at present.
Hypertension is a kind of chronic disease needing long-term monitoring and treatment, needs to take medicine throughout one's life.Existing Altace Ramipril is generally Western medicine, and Long-term taking medicine can have larger side effect to the liver of human body, kidney etc., and easily causes the uncomfortable reaction such as cough, edema, dizziness.Therefore, be necessary to find a kind of little to health side effect, low-cost effective hypotensor.
Summary of the invention
To the object of the invention is to overcome in prior art existing above-mentioned deficiency, a kind of blood pressure lowering Chinese medicine composition is provided, this Chinese medicine composition low price, little to patient body side effect for blood pressure lowering good effect.
In order to realize foregoing invention object, the invention provides following technical scheme:
Containing a blood pressure lowering Chinese medicine composition for Cyclocarya paliurus Iljinskaja, it is prepared from by the medicinal raw material of following weight proportion: Radix Et Rhizoma Fagopyri Tatarici 5 ~ 20 parts, Fructus Hippophae 5 ~ 12 parts, Cyclocarya paliurus Iljinskaja 3 ~ 10 parts, Semen Ziziphi Spinosae 3 ~ 10 parts, Stigma Maydis 1 ~ 5 part, Semen Cassiae 1 ~ 5 part.Described various medicinal raw material is the Chinese crude drug meeting country or provincial standard and specify.
Preferably, in above-mentioned medicinal raw material proportioning, part by weight shared by Radix Et Rhizoma Fagopyri Tatarici is 9 ~ 15 parts.Preferred, part by weight shared by Radix Et Rhizoma Fagopyri Tatarici is 12 parts.
Preferably, in above-mentioned medicinal raw material proportioning, part by weight shared by Fructus Hippophae is 7 ~ 10 parts.Preferred, part by weight shared by Fructus Hippophae is 8 parts.
Preferably, in above-mentioned medicinal raw material proportioning, part by weight shared by Cyclocarya paliurus Iljinskaja is 5 ~ 8 parts.Preferred, part by weight shared by Cyclocarya paliurus Iljinskaja is 6 parts.
Preferably, in above-mentioned medicinal raw material proportioning, part by weight shared by Semen Ziziphi Spinosae is 5 ~ 8 parts.Preferred, part by weight shared by Semen Ziziphi Spinosae is 6 parts.
Preferably, in above-mentioned medicinal raw material proportioning, part by weight shared by Stigma Maydis is 2 ~ 4 parts.Preferred, part by weight shared by Stigma Maydis is 3 parts.
Preferably, in above-mentioned medicinal raw material proportioning, part by weight shared by Semen Cassiae is 2 ~ 4 parts.Preferred, part by weight shared by Semen Cassiae is 3 parts.
The present invention is used for the Chinese medicine composition of blood pressure lowering, the active component of medicinal raw material can be extracted according to extracting method conventional on Chinese materia medica, add pharmaceutically acceptable carrier or/and adjuvant, as starch, dextrin, microcrystalline cellulose, amylum pregelatinisatum, magnesium stearate, micropowder silica gel, sucrose, carboxymethyl starch sodium, hydroxypropyl emthylcellulose, vegetable oil, lecithin, Polyethylene Glycol, propylene glycol, ethyl hydroxybenzoate etc., make dosage form suitable on pharmaceutics, as granule, tablet, hard capsule, oral liquid, soft capsule, drop pill, water pill etc.
The extracting method of Chinese medicine composition of the present invention can adopt but be not limited to following methods:
(1) get each medicinal raw material by formula proportion, in medicinal raw material, add 60 ~ 80% ethanol or the water of medicinal raw material volume 8 ~ 10 times; Reflux, extract, 2 ~ 3 times; Extraction time is respectively 1 ~ 2h; Collect merge extractive liquid, and extracting solution is condensed into extractum, dry, obtain the extract of medicinal raw material of the present invention.
(2) in above-mentioned extract, add pharmaceutic adjuvant and be mixed and made into acceptable various pharmaceutical dosage form on pharmaceutics.
According to the needs of the various drug form of preparation, medicine of the present invention also can add suitable pharmaceutic adjuvant as filler, disintegrating agent, binding agent, lubricant, antiseptic etc. in preparation process.
Compared with prior art, beneficial effect of the present invention:
The present invention be used for blood pressure lowering Chinese medicine composition, be inventor based on motherland's medical science to hypertensive pathogenetic understanding, according to oneself clinical experience for many years, first determine a series of to the effective Chinese medicine of blood pressure lowering from numerous Chinese medicine, repeatedly verify through clinical again, screen.Wherein, Radix Et Rhizoma Fagopyri Tatarici, bitter in the mouth, property is flat, cold; The real the intestines and stomach of energy, physical strength profiting, continuous spirit, sharp knowledge, refining the five internal organs slag is dirty; Also have calm the nerves, wind pain is swollen in the wide intestinal of lively atmosphere blood, sending down the abnormal ascending QI, heat clearing away, long-pendingization of dispelling is stagnant, bowel relieving, intestine moistening, relieving constipation, cough-relieving, the effect such as to relieving asthma.Fructus Hippophae, another name fructus hippophae, vinegar thorn willow, acid thorn, black thorn, vinegar willow; For the dry mature fruit of Elaeangnaceae hippophae plant Fructus Hippophae; Sour, puckery, temperature; There is eliminating phlegm and stopping cough, relieving dyspepsia, effect of promoting blood circulation to remove blood stasis; For cough with copious phlegm, dyspepsia, abdominal pain due to retention of food, blood stasis amenorrhea, falls diseases such as flutterring congestive edema.Cyclocarya paliurus Iljinskaja; Call blue or green money Lee, Folium hydrangeae strigosae tree; Juglandaceae Cyclocarya paliurus Iljinskaja., be used as medicine with leaf; Be mainly used in controlling tinea.Semen Ziziphi Spinosae, another name Fructus Choerospondiatis core, mountain Ziziphi Spinosae; For the dry mature seed of Rhamnaceae plant Ziziphi Spinosae; Sweet in the mouth, acid, property is put down; Return liver, gallbladder, heart channel; There is tonifying liver, mind calming, arresting sweating, the effect of promoting the production of body fluid; For restlessness of asrhenia type and insomnia, palpitation with fear dreaminess, the empty hyperhidrosis of body, Tianjin wound waits disease yearningly.Stigma Maydis, Stigma Maydis, another name Semen Maydis palpus, chinese sorghum palpus, Semen Maydis must; For style and the fresh idea of grass family Zea plant Zea mays; Sweet in the mouth, light, property is put down; Return bladder, liver, gallbladder meridian; There is inducing diuresis to remove edema, effect of suppressing the hyperactive liver function of gallbladder promoting; For acute and chronic nephritis, edema, acute hepatitis, chronic hepatitis, hypertension, diabetes, chronic sinusitis, lithangiuria, Biliary Calculi, the disease such as dysuria, damp and hot jaundice; And can habitual abortion be prevented.Semen Cassiae, another name Horse hoof Semen Cassiae, blunt leaf Semen Cassiae, false Semen phaseoli radiati, Semen Cassiae; For the dry mature seed of leguminous plant Semen Cassiae or little Semen Cassiae; Sweet, bitter, salty, be slightly cold; Return liver, large intestine channel; There is clearing away heat to improve acuity of vision, effect of loosening bowel to relieve constipation; For the puckery pain of conjunctival congestion, the many tear of photophobia, the diseases such as dizzy, poor vision, constipation of having a headache.Above-mentioned 6 taste Chinese herbal medicine, flavour of a drug are few but function is complete, 6 taste medicinal raw materials are by after described proportioning combination, for blood pressure lowering, there is Synergistic function, experimental study shows, Chinese medicine composition of the present invention is used for blood pressure lowering instant effect, good effect, and administration is after one week, can to take effect and evident in efficacy, and not occur obvious adverse reaction during patient consumes.
Detailed description of the invention
Below in conjunction with test example and detailed description of the invention, the present invention is described in further detail.But this should be interpreted as that the scope of the above-mentioned theme of the present invention is only limitted to following embodiment, all technology realized based on content of the present invention all belong to scope of the present invention.
In embodiments of the invention and comparative example, ethanol used is the aqueous solution of ethanol, and the percentage composition of ethanol, if no special instructions, is volumn concentration.
Embodiment 1
The present embodiment is used for the Chinese medicine composition of blood pressure lowering, is be prepared from by the medicinal raw material of following weight proportion: Radix Et Rhizoma Fagopyri Tatarici 12g, Fructus Hippophae 8g, Cyclocarya paliurus Iljinskaja 6g, Semen Ziziphi Spinosae 6g, Stigma Maydis 3g, Semen Cassiae 3g.
The extracting method of above-mentioned medicinal raw material:
(1) get each medicinal raw material by formula proportion, in medicinal raw material, add 60 ~ 80% ethanol or the water of medicinal raw material volume 8 ~ 10 times; Reflux, extract, 2 ~ 3 times; Extraction time is respectively 1 ~ 2h; Collect merge extractive liquid, and extracting solution is condensed into extractum, dry, obtain the extract of the medicinal raw material of embodiment 1.
(2) in above-mentioned extract, add the soluble starch of extract weight 2 times of weight, granulate, dry, be distributed into bag, obtain granule.
Embodiment 2
The present embodiment is used for the Chinese medicine composition of blood pressure lowering, is be prepared from by the medicinal raw material of following weight proportion: Radix Et Rhizoma Fagopyri Tatarici 20g, Fructus Hippophae 5g, Cyclocarya paliurus Iljinskaja 10g, Semen Ziziphi Spinosae 3g, Stigma Maydis 5g, Semen Cassiae 1g.
The above-mentioned medicinal raw material of the present embodiment for the preparation of the method for the Chinese medicine composition of blood pressure lowering with embodiment 1.
Embodiment 3
The present embodiment is used for the Chinese medicine composition of blood pressure lowering, is be prepared from by the medicinal raw material of following weight proportion: Radix Et Rhizoma Fagopyri Tatarici 14g, Fructus Hippophae 11g, Cyclocarya paliurus Iljinskaja 4g, Semen Ziziphi Spinosae 8g, Stigma Maydis 2g, Semen Cassiae 4g.
The above-mentioned medicinal raw material of the present embodiment for the preparation of the method for the Chinese medicine composition of blood pressure lowering with embodiment 1.
Comparative example
This comparative example is used for the Chinese medicine composition of blood pressure lowering, is be prepared from by the medicinal raw material of following weight proportion: Radix Et Rhizoma Fagopyri Tatarici 12g, Fructus Hippophae 8g, Semen Ziziphi Spinosae 6g, Stigma Maydis 3g, Semen Cassiae 3g.
The above-mentioned medicinal raw material of this comparative example for the preparation of the method for the Chinese medicine composition of blood pressure lowering with embodiment 1.
Pharmacodynamics and toxicity test:
In order to the efficacy and saferry of proved invention medicine, inventors performed pharmacodynamics and toxicity test investigation.The research method adopted and result of the test as follows:
1, test objective: the present invention is used for the Chinese medicine composition of blood pressure lowering to the hypotensive activity of original hypertensive rat.
2, test material
(1) medicine and reagent:
According to the Chinese medicine composition (making oral liquid) of embodiment 1 prepared by embodiment 1;
According to the Chinese medicine composition of comparative example prepared by comparative example, (making oral liquid);
Nifedipine Tablets: HARBIN PHARMACEUTICAL GROUP CO., LTD. General Pharm. Factory, (making oral liquid).
(2) animal: choose the original hypertensive rat 40 purchased from the laboratory animal department of the Chinese Academy of Sciences of Huaxi Medical Univ, body weight is 200 ~ 250g; Raise in positive pressure purification ventilation Animal House, room temperature 25 ± 2 DEG C, ad lib and drinking-water.
3, test method and result
Pretreatment before test: tested rat is put into measuring cell and carries out training 2 weeks, and blood pressure is measured second week rises the next day.The electrocaloric effect that before pressure measurement, animal puts into 37 ± 1 DEG C is heated, and measures rat systolic pressure after 15 minutes with RBP-1 type rat blood pressure instrument (Institute of Basic Medical Sciences of China-Japan Friendship Hospital, Beijing).
Process of the test: original hypertensive rat is divided into 4 groups at random, drug study group of the present invention, matched group 1, positive controls and model control group, often organize 10.The Chinese medicine composition oral liquid (7g raw medicinal herbs/kg, 1.5mL/50g) that the oral embodiment of the present invention of drug study group of the present invention 1 is obtained; The Chinese medicine composition oral liquid (7g raw medicinal herbs/kg, 1.5mL/50g) that the oral comparative example of the present invention of matched group 1 is obtained; Positive controls oral nifedipine sheet oral liquid (10mg/kg); The oral same volume distilled water of model control group, once a day, continuous 5 weeks.During administration and the ingesting of the mice respectively organized of fore-and-aft observing, movable and excretion situation situation all without exception occur.After administration the 1st, 2,3,4,5 weekends, measure the systolic pressure of rat, to measure 3 times at every turn, average.The blood pressure determination time after administration carries out after 2 hours in administration, and has measured in 4 hours upon administration.
Result of the test:
Adopt SPSS software to carry out statistical analysis, result of the test all represents with x ± s, and many group means compare employing ANOVA variance analysis, compare and check with q between group; There is significant P≤0.05 for difference.Result of the test is as shown in table 1, and table 1 was depicted as administration after 1 week, continuous 5 measurement statistical results to original hypertensive rat systolic pressure (unit: mmHg).
Table 1
Note: compare with model group:
*p<0.05; Compare with matched group 1:
▲ ▲p<0.05.
Experimental data in table 1 shows: the original hypertensive rat taking Chinese medicine composition oral liquid prepared by the embodiment of the present invention 1, administration is after 1 week, blood pressure starts to decline, continuously to the 4th weekend only, blood pressure is down to and is similar to normal value and substantially equal with the pressure value of positive controls; About 45mmHg is reduced relative to the rat blood pressure shrinkage value of model control group, and the Exemplary statistical data relative model matched group P<0.05 of medicine group of the present invention, there is significant difference.The present invention is used for the Chinese medicine composition of blood pressure lowering, for blood pressure lowering instant effect, good effect.
And matched group 1 shown in table 1 records rat blood pressure shrinkage value, after administration, blood pressure drops speed is slower.And administration is after 3 weeks, rat blood pressure shrinkage value still at about 120mmHg, and has no further decline.Chinese medicine composition for blood pressure lowering prepared by comparative example of the present invention, blood pressure lowering effect is poor; And the rat blood pressure shrinkage value statistical data of drug study group of the present invention is relative to the rat blood pressure shrinkage value statistical data P < 0.05 of matched group 1, has significant difference.Learn thus, the present invention is used for 6 kinds of medicinal raw materials of blood pressure lowering by after described weight proportion combination, and have Synergistic function, can significantly improve the curative effect of Chinese medicine composition, lack any component, the curative effect of Chinese medicine composition all significantly declines.
In sum, the present invention is containing the Chinese medicine composition for blood pressure lowering of Cyclocarya paliurus Iljinskaja, and for hyperpietic's blood pressure lowering short treating period, instant effect, administration can take effect and evident in efficacy for 1 week.6 kinds of medicinal raw materials, by after described weight proportion combination, have Synergistic function, can significantly improve the hypertensive curative effect of traditional Chinese medicine composition for treating; Lack any component, its curative effect all significantly declines, therapeutic effect as matched group 1 significantly reduces relative to the therapeutic effect of drug study group of the present invention, and blood pressure lowering traditional Chinese medicine composition for treating hypertension of the present invention is little to patient body side effect, is applicable to hyperpietic's long-term taking.
Claims (10)
1., containing a blood pressure lowering Chinese medicine composition for Cyclocarya paliurus Iljinskaja, it is characterized in that: it is prepared from by the medicinal raw material of following weight proportion: Radix Et Rhizoma Fagopyri Tatarici 5 ~ 20 parts, Fructus Hippophae 5 ~ 12 parts, Cyclocarya paliurus Iljinskaja 3 ~ 10 parts, Semen Ziziphi Spinosae 3 ~ 10 parts, Stigma Maydis 1 ~ 5 part, Semen Cassiae 1 ~ 5 part.
2. blood pressure lowering Chinese medicine composition according to claim 1, is characterized in that: part by weight shared by Radix Et Rhizoma Fagopyri Tatarici is 9 ~ 15 parts.
3. blood pressure lowering Chinese medicine composition according to claim 2, is characterized in that: part by weight shared by Radix Et Rhizoma Fagopyri Tatarici is 12 parts.
4. blood pressure lowering Chinese medicine composition according to claim 1, is characterized in that: part by weight shared by Fructus Hippophae is 7 ~ 10 parts.
5. blood pressure lowering Chinese medicine composition according to claim 4, is characterized in that: part by weight shared by Fructus Hippophae is 8 parts.
6. blood pressure lowering Chinese medicine composition according to claim 1, is characterized in that: part by weight shared by Cyclocarya paliurus Iljinskaja is 5 ~ 8 parts.
7. blood pressure lowering Chinese medicine composition according to claim 6, is characterized in that: part by weight shared by Cyclocarya paliurus Iljinskaja is 6 parts.
8. blood pressure lowering Chinese medicine composition according to claim 1, is characterized in that: part by weight shared by Semen Ziziphi Spinosae is 5 ~ 8 parts.
9. blood pressure lowering Chinese medicine composition according to claim 1, is characterized in that: part by weight shared by Stigma Maydis is 2 ~ 4 parts.
10. blood pressure lowering Chinese medicine composition according to claim 1, is characterized in that: part by weight shared by Semen Cassiae is 2 ~ 4 parts.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410631835.7A CN104435814A (en) | 2014-11-11 | 2014-11-11 | Traditional Chinese medicine composition containing cyclocarya paliurus and having function of reducing blood pressure |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410631835.7A CN104435814A (en) | 2014-11-11 | 2014-11-11 | Traditional Chinese medicine composition containing cyclocarya paliurus and having function of reducing blood pressure |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN104435814A true CN104435814A (en) | 2015-03-25 |
Family
ID=52883075
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410631835.7A Pending CN104435814A (en) | 2014-11-11 | 2014-11-11 | Traditional Chinese medicine composition containing cyclocarya paliurus and having function of reducing blood pressure |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104435814A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111346127A (en) * | 2020-04-20 | 2020-06-30 | 浙江众博堂生物科技有限公司 | Cyclocarya paliurus traditional Chinese medicine composition and application thereof |
-
2014
- 2014-11-11 CN CN201410631835.7A patent/CN104435814A/en active Pending
Non-Patent Citations (2)
| Title |
|---|
| 柴瑞震: "《常见病对症食疗速查手册》", 31 August 2013, 黑龙江科学技术出版社 * |
| 高纪武等: "《高纪武医案》", 30 September 2012, 第四军医大学出版社 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111346127A (en) * | 2020-04-20 | 2020-06-30 | 浙江众博堂生物科技有限公司 | Cyclocarya paliurus traditional Chinese medicine composition and application thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101011561B (en) | Modern traditional Chinese medicine oral preparation huanglianwendan decoction and production method thereof | |
| CN100366280C (en) | Medicinal composition for treating hypertension, its preparation method and use | |
| CN1840166A (en) | Modern Chinese medicinal oral liquid of 'Wen Dan Tang' and preparation method thereof | |
| CN104904964A (en) | Folium apocyni veneti health tea capable of decreasing sugar and lipid and preparation method thereof | |
| CN106177053A (en) | A kind of Hyperglycemic health care compositions comprising leaf of Cyclocarya paliurus Iljinskaja and Pericarpium Citri Reticulatae | |
| CN102688307B (en) | Traditional Chinese medicine composition Xueshan Weibao chewable tablet and preparation method thereof | |
| CN104435814A (en) | Traditional Chinese medicine composition containing cyclocarya paliurus and having function of reducing blood pressure | |
| CN1943755B (en) | A Chinese traditional medicinal composition for treatment of hypertension and its preparation method | |
| CN104324134B (en) | One kind improves microcirculatory Chinese medicine composition and preparation method thereof | |
| CN104352561A (en) | Radix achyranthis bidentatae-containing traditional Chinese medicine composition for lowering blood pressure | |
| CN105194355A (en) | Traditional Chinese medicine preparation for treating primary hypertension | |
| CN101991722B (en) | Shiqi exogenous disease-treating traditional Chinese medicinal capsules | |
| CN100484536C (en) | Capsule for treating enteritis and dysentery and its preparing process | |
| CN104784530B (en) | A kind of Chinese medical extract of blood pressure lowering and preparation method thereof | |
| CN104000907A (en) | Traditional Chinese medicine for treating chronic urticaria and preparation method thereof | |
| CN104223062B (en) | Root bark of Chinese wolf-berry health care oral liquid of a kind of reducing pressure and sugar and preparation method thereof | |
| CN103768129A (en) | Drug composition for preventing or treating hypertension | |
| CN104352860A (en) | Oenothera biennis-containing traditional Chinese medicine composition for lowering blood pressure | |
| CN106728828A (en) | A kind of Chinese medicine preparation and its preparation technology for treating coronary heart disease | |
| CN104352816A (en) | Developed pear leaf-containing traditional Chinese medicine composition for lowering blood pressure | |
| CN104435166A (en) | Traditional Chinese medicine composition containing panax japonicus for reducing blood pressure | |
| CN104352570A (en) | Incarvillea mairei-containing traditional Chinese medicine composition for lowering blood pressure | |
| CN104352815A (en) | Lysimachia fortunei-containing traditional Chinese medicine composition for lowering blood pressure | |
| CN104383012A (en) | Traditional Chinese medicine composition containing phoenix tree leaf for reducing blood pressure | |
| CN105943860A (en) | Medicine preparation for treating diabetes mellitus and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20150325 |