CN104322552B - A kind of weeding pharmaceutical composition and its preparation - Google Patents
A kind of weeding pharmaceutical composition and its preparation Download PDFInfo
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- CN104322552B CN104322552B CN201410556822.8A CN201410556822A CN104322552B CN 104322552 B CN104322552 B CN 104322552B CN 201410556822 A CN201410556822 A CN 201410556822A CN 104322552 B CN104322552 B CN 104322552B
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- weeding
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- picloram
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Abstract
The invention discloses a kind of weeding pharmaceutical composition and its preparation, the component of described pesticide active ingredient and its weight portion are 10 150 parts of picloram, 300 700 parts of glyphosate, 1 100 parts of azoles humulone.Dosage form is wettable powder, soluble powder, soluble granula, water dispersible granules and microemulsion.The advantage of said composition has obvious potentiation after being to compound, and improves weeding speed, expands weed control spectrum, significantly reduces usage amount and the access times of herbicide.It is applied to annual grassy weeds and the perennial weeds such as preventing and treating Herba Imperatae, Bermuda grass, Herba Digitariae, ferrum awn winnow basket, bidens pilosa.
Description
Technical field
The present invention relates to agriculture chemical field is and in particular to a kind of weeding pharmaceutical composition and its preparation.
Background technology
Picloram also known as picloram, English common name picloram, chemical name is：4- amino -3,5,6- trichlorines
Picolinic acid, its CA registration number：1918-02-1, molecular formula C6H3Cl3N2O2, molecular weight 291.2, is a kind of pyridines herbicide,
Nucleic acid metabolism can be mainly acted on readily through leaf and root absorption and conduction, and make chloroplast structure and other organelles
Developmental disorder, interferencing protein synthesizes, and acts on separate living tissue activity etc., finally results in Plant death.Except crop in cruciferae
Outer most of broad leaf crop is all sensitive to this product.
Glyphosate reaches also known as agriculture, glyphosate, english common name glyphosate, CA registration number：1071-83-6, chemistry
Title N- (phosphoric acid methyl) glycine.Molecular formula C3H8NO5P, molecular weight 169.09.It is a kind of organic phosphates herbicide, be also stem
The inner-adsorption conduction-type herbicide that leaf absorbs, enolpyruvyl shikimene phosphate synthase in major inhibitor body, thus suppress big
Grass element, to the conversion of Phenylalanine, cruel propylhomoserin and tryptophan, makes the synthesis of protein be interfered and leads to Plant death, can be used for
Prevent and kill off monocotyledon weed and part broad leaved weed.
Azoles humulone is also known as spirit of going out soon, triazolone grass ester, carfentrazone, English common name carfentrazone-ethyl, chemistry
Entitled：Ethyl -2- chloro- 3- the chloro- 5- of 2- [4- (difluoromethyl) -4,5- dihydro -3- methyl -5- oxygen -1H-1,2,4- triazole -
1- yl] -4- fluorophenyl } ethyl propionate, its CA registration number：128639-02-1, molecular formula C15H14Cl2F3N3O3, molecular weight
412.2, it is a kind of triazolineone herbicide, it has good low temperature resistant and resistance of rainwater washing against effect, can suppress former porphin
The former oxidase of quinoline leads to the accumulation of poisonous intermedium, makes blade withered, dead rapidly, can be used for preventing and kill off broad leaved weed and dried tuber.
Chinese patent disclose some piclorams, glyphosate and azoles humulone and with other compound groups synthesis remove
Careless agent, for example：200910210982.6, picloram electrostatic spray oil agent and preparation method thereof；201210223900.3, contain
There are compound pesticide composition, preparation and the application of picloram or its salt；201310267260.0, containing glufosinate-ammonium and azoles grass
The Herbicidal combinations of ketone；201110153285.9, the Herbicidal combinations of a kind of grass containing azole ketones and pyraflufen-ethyl；
201110187160.8,200910034319.5, azoles humulone cyhalofop-butyl dichloro quinolinic acid complex weedicide；
201110157619.X, the Herbicidal combinations of a kind of grass containing azole ketones and Brominal；201110349306.4, one kind contains ethoxysulfuron
Herbicidal combinations with azoles humulone；201310266760.2, a kind of mixture preparation of glyphosate-Mediben and preparation method thereof；
201310013797.4, a kind of herbicide expanding glyphosate weed control spectrum；201310491482.0, containing glyphosate, 2 first 4 chlorine and
The herbicidal composition of azoles humulone；201210574042.7, the weeding containing glyphosate, the different monooctyl ester of fluroxypyr and azoles humulone
Agent compositionss etc..Show picloram, glyphosate and azoles humulone and their herbicides with other compound group synthesis
There is preferable herbicide effect and be applied to agriculturally.
Use the research of picloram, glyphosate and this 3 kinds of mixture of herbicides of azoles humulone at present and apply not disclosed literary composition
Offer report.
Herba Imperatae, Bermuda grass, Herba Digitariae, ferrum awn winnow basket, bidens pilosa etc. are common miscellaneous in various crop field and bare place
Grass, is used alone picloram, glyphosate and azoles humulone can not prevent and kill off these weeds simultaneously, and, single in actual applications
Not only speed is slow for only weeding using picloram and glyphosate, and is easily affected by bad climates such as low temperature, rainfalls, limits
The performance of drug effect.
Different herbicides carry out compounding can expand weed control spectrum, and adopt the different mixture of herbicides of model of action and show
Potentiation is shown, that is, mixture is higher than the desired value of each component independent role in mixture to the inhibitory action of weed growth, makes
Weeds are difficult to eliminate the impact to its metabolic pathway for the different herbicides, and then delay the generation of Weed Resistance, are exploitation herbicides
The target of complex preparation, is also to mitigate environmental pollution, reduces the effective means of herbicide residue.Through screening, by picloram,
Glyphosate, azoles humulone compound and enable above-mentioned advantage, and the compositionss containing mentioned component also have the fireballing feature of herbicide, are suitable for
Application under low temperature, rainfall gap condition, is that the weeds such as Herba Imperatae, Bermuda grass, Herba Digitariae, ferrum awn winnow basket, bidens pilosa chemistry is anti-
The fine herbicide removing.
Content of the invention
The present invention provides the compounding weeding pharmaceutical composition of a kind of picloram, glyphosate and azoles humulone and its preparation,
There is between this herbicide effective ingredient synergistic function, improve herbicide speed, weed control spectrum can also be widened, formation one is high
Effect, wide spectrum, the herbicide kind of low cost, this herbicide can be wettable powder, soluble powder, soluble granula, water
Dispersible granule and microemulsion.
Weeding pharmaceutical composition of the present invention, is prepared from by the raw material including following weight portion：Picloram
10-150 part, glyphosate 300-700 part, azoles humulone 1-100 part.
Preferably：Picloram 50-100 part, glyphosate 300-500 part, azoles humulone 1-50 part.
Weeding pharmaceutical composition of the present invention, is prepared from by the raw material including following weight portion：Picloram
10-150 part, glyphosate 300-700 part, azoles humulone 1-100 part, auxiliary agent 50-689 part.
Described auxiliary agent includes the filler of 10-500 weight portion.
Described auxiliary agent also includes the adhesive of 10-200 weight portion.
Described filler is kieselguhr, bentonite, Kaolin, attapulgite, clay, white carbon, precipitated calcium carbonate and cunning
One of stone powder or more than one combination.
Described adhesive is cellulose and its modifier, starch and its modifier, animal glue, polyvinyl acetate and
One of sodium silicate or more than one combination.
Described goes back the solvent that auxiliary agent includes 100-400 weight portion.
Described auxiliary agent also includes 10-50 weight portion cosolvent, the surfactant of 10-200 weight portion, 10-50 weight
One of the defoamer of part, 10-100 weight portion antifreezing agent or more than one combination.
Described solvent is N, N- dimethyl pyrrolidone, ethanol, cyclohexanone, isopropanol, dichloromethane, hexamethylene, chlorine
One of imitative and purified water or more than one combination；Described cosolvent is Oleic acid glyceryl ester, acetamide, glycerol, poly- second
One of glycol, propylene glycol and glycerol or more than one combination.
Described surfactant is stearic acid, sodium laureth sulfate, dodecylbenzene sodium sulfonate, detergent alkylate sulfur
Sour sodium, sodium butylnaphthalenesulfonate, sodium lignin sulfonate, sodium methylene bis-naphthalene sulfonate, calcium lignosulfonate, polyethers ichthyodin, fat
Polyoxyethylenated alcohol sodium sulfonate, alkanolamide sodium sulfonate of ethoxylated, calcium dodecyl benzene sulfonate, alkyl poly glucoside, alkyl
Aryl polyoxyethylene polyoxypropylene ether, phenethyl phenol polyethenoxy ether, alkylphenol polyoxyethylene, fatty glyceride and poly- mountain
One of pear ester or more than one combination.
Described defoamer is one of isooctanol, organosiloxane, emulsified silicone oil and polypropylene glycerol aether or one
Plant above combination.
Described antifreezing agent is one of ethylene glycol, propylene glycol, butyl glycol ether and carbamide or more than one combination.
Herbicidal composition provided by the present invention can apply to prevent and treat Herba Imperatae, Bermuda grass, Herba Digitariae, ferrum awn winnow basket, SANYE
The arable lands such as Herba Bidentis Bipinnatae and bare place weeds.
The present invention has following remarkable result：
(1) each effective ingredient of the present invention increased the activity of intermixture after compounding, and potentiation substantially, significantly reduces and removes
The usage amount of careless agent and access times, have saved cost.
(2) each effective ingredient of the present invention expands weed control spectrum after compounding, and can prevent and treat multiple weeds simultaneously, decrease labor
Power.
(3) each effective ingredient of the present invention makes weeds be difficult to eliminate the different herbicide of mechanism of action to its metabolism way after compounding
The impact in footpath, delays the individual generation of Drug resistance in weeds.
(4) herbicidal composition provided by the present invention improves weeding speed, reduces the bad climates such as low temperature, rainfall
Impact to drug effect.
Specific embodiment
Further illustrate the present invention below by embodiment.It should be understood that embodiments of the invention are for illustrating
The present invention rather than limitation of the present invention.Broadly fall into the present invention according to the simple modifications that the essence of the present invention is carried out to the present invention
Claimed scope.In following examples, percentage ratio is all weight percentage.
Embodiment 1
Picloram 15kg, sodium glyphosate are with glyphosate amount of calculation as 30kg, azoles humulone 10kg, lauryl sulphate acid
Sodium 12kg, sodium lignin sulfonate 8kg, sodium methylene bis-naphthalene sulfonate 8kg, white carbon 18kg.First white carbon and azoles humulone are added
Mix homogeneously in batch mixer, then by picloram, sodium glyphosate, sodium lauryl sulphate, sodium lignin sulfonate and methylene
The double sodium naphthalene sulfonate of base sequentially adds in batch mixer and is sufficiently mixed, and is crushed to thin in the material addition jet mill after mix homogeneously
Degree reaches 325 mesh, obtains the composite wettable powder that active constituent content is 55%.
Embodiment 2
Picloram 2.5kg, sodium glyphosate are with glyphosate amount of calculation as 60kg, azoles humulone 0.5kg, lauryl alcohol sulfur
Sour sodium 2kg, lauryl sulphate acid calcium 2kg, dodecylbenzene sodium sulfonate 4kg, precipitated calcium carbonate 29kg.First by precipitated calcium carbonate and
Azoles humulone adds mix homogeneously in batch mixer, then by picloram, sodium glyphosate, sodium laureth sulfate, dodecyl
Calcium sulfate and dodecylbenzene sodium sulfonate sequentially add in batch mixer and are sufficiently mixed, and the material after mix homogeneously adds comminution by gas stream
It is crushed to fineness in machine and reaches 325 mesh, obtain the composite wettable powder that active constituent content is 63%.
Embodiment 3
Picloram 10kg, glyphosate potassium are with glyphosate amount of calculation as 70kg, azoles humulone 7kg, alkanolamide polyoxy
Vinyl Ether sodium sulfonate 2kg, polyoxyethylene fatty alkyl ether sulfonate 2kg, dodecylbenzene sodium sulfonate 1kg, attapulgite 8kg.First
Attapulgite and azoles humulone are added mix homogeneously in batch mixer, then by picloram, glyphosate potassium, alkanolamide polyoxy
Vinyl Ether sodium sulfonate, polyoxyethylene fatty alkyl ether sulfonate, dodecylbenzene sodium sulfonate sequentially add in batch mixer and are sufficiently mixed,
It is crushed to fineness in material addition jet mill after mix homogeneously and reaches 325 mesh, obtaining active constituent content is 87%
Composite wettable powder.
Embodiment 4
Picloram 2kg, glyphosate potassium are with glyphosate amount of calculation as 45kg, azoles humulone 1kg, aliphatic alcohol polyethenoxy
Ether sulfonic acid sodium 2kg, calcium lignosulfonate 2kg, dodecylbenzene sodium sulfonate 4kg, kieselguhr 44kg.First by kieselguhr and azoles humulone
Add mix homogeneously in batch mixer, then by picloram, glyphosate potassium, polyoxyethylene fatty alkyl ether sulfonate, lignin
Sulfoacid calcium and dodecyl phenenyl sulfate sequentially add in batch mixer and are sufficiently mixed, and the material after mix homogeneously adds comminution by gas stream
It is crushed to fineness in machine and reaches 325 mesh, obtain the composite wettable powder that active constituent content is 48%.
Embodiment 5
Picloram 2.5kg, glyphosate 30kg, azoles humulone 0.5kg, sodium laureth sulfate 2kg, calcium lignosulfonate
2kg, dodecylbenzene sodium sulfonate 4kg, methanol 5kg, ammonium sulfate 54kg.By azoles humulone, methanol, calcium dodecyl benzene sulfonate, the moon
Laureth sulfate is sufficiently stirred for dissolving in container, is configured to homogeneous liquid phase.By picloram, glyphosate, sulfomethylated lignin
Sour calcium and ammonium sulfate sequentially add in batch mixer and are sufficiently mixed, and are crushed to thin in the material addition jet mill after mix homogeneously
Degree reaches 325 mesh, is configured to homogeneous solid phase.Afterwards liquid phase is slowly added in the solid phase of formula ratio, mix and blend 1 hour, obtains
The compositionss soluble powder being 33% to active constituent content.
Embodiment 6
Picloram 10.8kg, sodium glyphosate press glyphosate amount of calculation be 60kg, azoles humulone 0.2kg, ethanol 4kg,
Calcium dodecyl benzene sulfonate 0.4kg, alkylphenol polyoxyethylene 0.5kg, sodium lignin sulfonate 4kg, alkanolamide polyoxyethylene
Ether sulfonic acid sodium 2kg, starch sulfate 10kg, sodium sulfate 8.1kg.
Azoles humulone, ethanol, calcium dodecyl benzene sulfonate, alkylphenol polyoxyethylene are sufficiently stirred for dissolving in container,
It is configured to homogeneous liquid phase.By picloram, glyphosate, sodium lignin sulfonate, alkanolamide sodium sulfonate of ethoxylated, sulphuric acid
Sodium sequentially adds in batch mixer and is sufficiently mixed, and is crushed to fineness and reaches 325 in the material addition jet mill after mix homogeneously
Mesh.Afterwards liquid phase is slowly added in the solid phase of formula ratio and mixes 1 hour, form certain density premix material.Starch sulfate
With water by weight 1：2 mix homogeneously, abundant gelatinizing at 80 DEG C.Premix material is added together with the starch sulfate after gelatinizing
Make soluble granula in Squeezinggranulator, drying, cooling, screening, after inspection, carry out finished product packing.
Embodiment 7
Picloram 1kg, glyphosate 35kg, azoles humulone 4kg, sodium lignin sulfonate 4kg, alkanolamide polyoxyethylene ether
Sodium sulfonate 2kg, polyoxyethylene fatty alkyl ether sulfonate 2kg, starch sulfate 10kg, bentonite 42kg.First by bentonite and azoles
Oxadiazon adds mix homogeneously in batch mixer, then by picloram, glyphosate, sodium lignin sulfonate, alkanolamide polyoxyethylene
Ether sulfonic acid sodium, polyoxyethylene fatty alkyl ether sulfonate sequentially add in batch mixer and are sufficiently mixed, and the material after mix homogeneously adds
It is crushed to fineness in jet mill and reaches 325 mesh, then the material after pulverizing is added mixing 1 hour in batch mixer, form one
Determine the premix material of concentration.Starch sulfate and water by weight 1：2 mix homogeneously, abundant gelatinizing at 80 DEG C.By premix material
Add together with the starch sulfate after gelatinizing in Squeezinggranulator and make water dispersible granules, drying, cooling, screening, inspection
Afterwards, carry out finished product packing.
Embodiment 8
It is 45kg, azoles humulone 8kg, alkanolamide polyoxy that picloram 12kg, sodium glyphosate press glyphosate amount of calculation
Vinyl Ether sodium sulfonate 10kg, Radix Acaciae senegalis 9kg, clay 8kg, Pulvis Talci 8kg.First clay and azoles humulone are added in batch mixer
Mix homogeneously, then Pulvis Talci, picloram, glyphosate, alkanolamide sodium sulfonate of ethoxylated are sequentially added batch mixer
In be sufficiently mixed, material after mix homogeneously adds and is crushed to fineness in jet mill and reaches 325 mesh, is formed certain density
Premix material.Radix Acaciae senegalis and appropriate water dissolution, premix material is added extruding to make together with the Radix Acaciae senegalis after dissolving
Make water dispersible granules in grain machine, drying, cooling, screening, check after, carry out finished product packing.
Embodiment 9
It is 70kg, azoles humulone 1kg, calcium lignosulfonate that picloram 2kg, glyphosate potassium press glyphosate amount of calculation
4kg, polyethers ichthyodin 4kg, carboxymethyl cellulose 8kg, kieselguhr 11kg.First kieselguhr and azoles humulone are added mixed in batch mixer
Close uniformly, then picloram, glyphosate, calcium lignosulfonate, polyethers ichthyodin sequentially added in batch mixer and be sufficiently mixed,
Material after mix homogeneously adds and is crushed to fineness in jet mill and reaches 325 mesh, then the material after pulverizing adds batch mixing
Mix 1 hour in machine, form certain density premix material.Carboxymethyl cellulose with appropriate water dissolution, by premix material with molten
Carboxymethyl cellulose after solution adds in Squeezinggranulator together makes water dispersible granules, drying, cooling, screening, inspection after,
Carry out finished product packing.
Embodiment 10
It is 30kg, azoles humulone 0.5kg, detergent alkylate that picloram 1.5kg, sodium glyphosate press glyphosate amount of calculation
Sulfoacid calcium 3kg, alkylphenol polyoxyethylene 7kg, sodium silicate 9kg, Kaolin 49kg.First Kaolin and azoles humulone are added batch mixing
Mix homogeneously in machine, then picloram, glyphosate, calcium dodecyl benzene sulfonate, alkylphenol polyoxyethylene are sequentially added
It is sufficiently mixed in batch mixer, be crushed to fineness in the material addition jet mill after mix homogeneously and reach 325 mesh, then will pulverize
Material afterwards adds in batch mixer and mixes 1 hour, forms certain density premix material.Sodium silicate with appropriate water dissolution, incite somebody to action
Premix material adds and makes water dispersible granules in Squeezinggranulator together with after the sodium silicate after dissolving, drying, cooling, screening,
After inspection, carry out finished product packing.
Embodiment 11
Picloram 2kg, glyphosate 30kg, azoles humulone 2kg, N, N- dimethyl pyrrolidone 10kg, detergent alkylate
Sulfoacid calcium 3kg, alkyl poly glucoside 3kg, alkylaryl polyoxyethylene polyoxypropylene ether again 1kg, propylene glycol 5kg, remaining purified water 36kg.
By picloram, azoles humulone, dichloromethane, calcium dodecyl benzene sulfonate, alkyl poly glucoside, alkylaryl polyoxypropylene polyoxy
Vinyl Ether, propylene glycol are sufficiently stirred for dissolving in container, are configured to homogeneous oil phase.Will be mixed in container stirring to glyphosate and water
Close, be configured to homogeneous aqueous phase.Afterwards oil phase is slowly added in the aqueous phase of formula ratio, mix and blend 1 hour, obtains effective ingredient
Content is 42% composite microemulsion.
Embodiment 12
Picloram 13.5kg, glyphosate 32kg, azoles humulone 0.5kg, ethanol 14kg, calcium dodecyl benzene sulfonate 4kg,
Phenethyl phenol polyethenoxy ether 2kg, fatty glyceride 2kg, ethylene glycol 1kg, propylene glycol 1kg, purified water 30kg.By ammonia chlorine pyrrole
Pyridine acid, azoles humulone, chloroform, calcium dodecyl benzene sulfonate, phenethyl phenol polyethenoxy ether, fatty glyceride, ethylene glycol, the third two
Alcohol is sufficiently stirred for dissolving in container, is configured to homogeneous oil phase.Glyphosate and water are stirred mixing in container, is configured to homogeneous
Aqueous phase.Afterwards oil phase is slowly added in the aqueous phase of formula ratio, mix and blend 1.5 hours, obtaining active constituent content is 46%
Composite microemulsion.
Embodiment 13
Picloram 8kg, glyphosate 50kg, azoles humulone 5kg, dichloromethane 12kg, calcium dodecyl benzene sulfonate 3kg,
Alkylaryl polyoxyethylene polyoxypropylene ether again 2kg, Polysorbate 3kg, glycerol 3kg, purified water 14kg.By picloram,
Azoles humulone, dichloromethane, calcium dodecyl benzene sulfonate, alkylaryl polyoxyethylene polyoxypropylene ether again, Polysorbate, glycerol in
It is sufficiently stirred in container dissolving, be configured to homogeneous oil phase.Glyphosate and water are stirred mixing in container, is configured to homogeneous water
Phase.Afterwards oil phase is slowly added in the aqueous phase of formula ratio, mix and blend 2 hours, obtains the combination that active constituent content is 63%
Thing microemulsion.
Embodiment 14
By indoor biometricses, specify the potentiation situation after glyphosate, azoles humulone and pyridines mixture of herbicides, wherein pyridine
The species of class herbicide has 1. picloram (picloram)；2. chlorine Fampridine acid (aminopyralid)；3. Triclopyr
(triclopyr)；4. clopyralid (clopyralid).Object is surveyed as raw using Herba Imperatae, native from not applying herbicide
Earth, pH6.8, soil is air-dried after sieving, load diameter 32cm, in the plastic flowerpot (having pallet) of deep 20cm, every basin plantation 15
The healthy and strong 2 consistent leaf phase seedling of strain are for test.Using stem and leaf nebulization, with reference to NY/T1155.4-2006 pesticide indoor biological
Determination test criterion herbicide the 4th part：Active determination test stem and leaf nebulization is tested, and often processes 4 repetitions, often repeats
15 plants of plants, if be blank without chemicals treatment.Data statistical analysis method is with reference to NY/T 1155.7-2006 pesticide room
Interior bioassay test criterion herbicide the 7th part：Colby method in the synergy mensure of mixture, calculates each mixture group
Rationally discuss survival rate E0Difference (the E of value, actual survival rate E value and theoretical value and actual value0-E).E0-E>10% makees for potentiation
With；E0-E<- 10% is antagonism；E0- E value is addition between ± 10%.
The results are shown in Table 1.
Table 1 glyphosate, the azoles humulone and pyridines mixture of herbicides Toxicity Determination to Herba Imperatae
Glyphosate, azoles humulone and pyridines mixture of herbicides as seen from the table, the co-toxicity coefficient to Herba Imperatae for each proportioning of mixture
All>- 10%, antagonism does not occur, illustrate that glyphosate, azoles humulone and pyridines mixture of herbicides are feasible.Identical
Under dosage and ratio, when glyphosate, azoles humulone and picloram compound, each proportioning of mixture is to Herba Imperatae survival rate difference (E0-E)
Higher than other combinations, illustrate glyphosate, azoles humulone and picloram potentiation apparently higher than other combinations.
Embodiment 15 (picloram, the glyphosate and triazolineone mixture of herbicides Toxicity Determination to weeds)
On the basis of embodiment 14, by indoor biometricses, specify picloram, glyphosate and triazolineone weeding
Potentiation situation after agent is compounding, the species of wherein triazolineone herbicide has 1. azoles humulone；2. amicarbazone
(amicarbazone)；3. procarbazone (propoxycarbazone)；4. sulfentrazone (sulfentrazone)；5. azoles pyridine
Oxadiazon (azafenidin).Equally object is surveyed as raw using Herba Imperatae, test method and synegism evaluation, with embodiment 11, are tied
Fruit is shown in Table 2.
Table 2 picloram, the glyphosate and triazolineone mixture of herbicides Toxicity Determination to Herba Imperatae
Picloram, glyphosate and triazolineone mixture of herbicides as seen from the table, each proportioning of mixture is to Herba Imperatae
Co-toxicity coefficient is equal>- 10%, antagonism does not occur, illustrate that picloram, glyphosate and triazolineone herbicide are multiple
It is feasible for joining.Compared with other combinations, when picloram, glyphosate and azoles humulone compound, each proportioning of mixture is deposited to Herba Imperatae
Motility rate difference (E0- E) process higher than other, illustrate that the potentiation that picloram, glyphosate and azoles humulone compound is substantially high
In other combinations.
(picloram, azoles humulone and glyphosate and other broad spectrum weeding agent compound the room to Herba Imperatae to embodiment 16
Interior toxicity test)
Potentiation situation after picloram, azoles humulone and broad spectrum weeding agent are compounding, the species of broad spectrum weeding agent has
1. glyphosate；2. glufosinate-ammonium (glufosinate-ammonium)；3. N,N'-dimethyl-.gamma..gamma.'-dipyridylium (paraquat)；4. hexazinone
(hexazinone)；5. diuron (diuron)；6. Brominal (bromoxynil)；7. 2 first 4 chlorine sodium (MCPA-Na)；8. green bristlegrass is gone out
Only (ametryn).Equally object is surveyed as raw using Herba Imperatae, with embodiment 14, result is shown in for test method and synegism evaluation
Table 3.
Table 3 picloram, azoles humulone and broad spectrum weeding agent compound the Toxicity Determination to Herba Imperatae
When picloram, azoles humulone and glyphosate compound as seen from the table, each proportioning of mixture is to Herba Imperatae survival rate difference
(E0- E) combining higher than picloram and azoles humulone and other broad spectrum weeding agent, illustrate picloram, azoles humulone and
Glyphosate potentiation is the most obvious.
Embodiment 17 (containing picloram, the glyphosate and azoles humulone herbicidal composition Toxicity Determination to weeds)
By indoor biometricses, specify the potentiation situation after picloram, glyphosate and azoles humulone compound.According to ammonia chlorine pyrrole
The effective object and product of pyridine acid, glyphosate and azoles humulone purposes from now on is right as raw survey using Herba Imperatae, Bermuda grass, ferrum awn winnow basket
As, test method and synegism evaluation are with embodiment 14, the results are shown in Table 4.
Table 4 contains picloram, the glyphosate and azoles humulone herbicidal composition Toxicity Determination to weeds
Picloram, glyphosate and azoles humulone compound each test proportioning to Herba Imperatae, Bermuda grass, ferrum awn winnow basket as seen from the table
All performance notable synergistic effects, i.e. theoretical survival rate E0Value is all higher than 10% with the difference of actual survival rate E value.Therefore ammonia chloropyridine
It is feasible that acid, glyphosate and azoles humulone compound.
Embodiment 18 (containing picloram, the glyphosate and azoles humulone herbicidal composition field medicine effect test to weeds)
On Guangxi Dongxing City flame farm, field medicine effect test is carried out to obtained product in June, 2012, field is excellent
Gesture weeds are Herba Imperatae, Bermuda grass, Herba Digitariae, ferrum awn winnow basket, bidens pilosa.Test medicine is the product obtained by embodiment 1～13,
Comparison medicament is 22% picloram water preparation, 30% gyphosate solution, 40% azoles humulone water dispersible granules.Test medicine and
The concentration of 30% gyphosate solution is 1680g a.i./hm2, the concentration of 22% picloram water preparation is 180g
a.i./hm2(by Products Show dosage), the concentration of 40% azoles humulone water dispersible granules is 36g a.i./hm2(push away by product
Recommend dosage).Test and statistical method, with reference to GB-T17980.51-2000, routine observation record, are adjusted using absolute-value scheme
Look into, with the fresh weight preventive effect of investigation in the 42nd day as final result.Result of the test shows, the product obtained by embodiment 1～13 and
40% azoles humulone water dispersible granules are applied latter 24 hours, and part weeds occur as soon as poisoning symptom, just have within the 4th day weeds dead.And
22% picloram water preparation and 30% gyphosate solution after application after 72 hours part weeds just start that poisoning symptom occurs,
7th day weeds occur dead, in quick-acting, the product obtained by embodiment 1～13 be better than 22% picloram water preparation and
30% gyphosate solution, and 40% azoles humulone water-dispersible grain is suitable.Fresh weight preventive effect was investigated in 42nd day, result such as table 5.
Field efficacy (fresh weight preventive effect) the Guangxi Dongxing in 2012 to weeds for table 5 test medicine
Field medicine effect test result shows, each process containing picloram, glyphosate and azoles humulone herbicidal composition is right
All more than 80%, under same concentrations, embodiment 1～13 is each to be processed drug effect and kills the control in field effect (fresh weight preventive effect) of weeds
Grass spectrum is superior to comparison medicament 30% gyphosate solution, is also better than 22% picloram water preparation under recommended dose and 40% azoles
Oxadiazon water dispersible granules.
Claims (13)
1. a kind of weeding pharmaceutical composition is it is characterised in that be prepared from by the raw material including following weight portion：Picloram
4-60 part, glyphosate 120-280 part, azoles humulone 0.4-40 part.
2. a kind of weeding drug combination preparation is it is characterised in that be prepared from by the raw material including following weight portion：Ammonia chlorine pyrrole
Pyridine acid 4-60 part, glyphosate 120-280 part, azoles humulone 0.4-40 part, auxiliary agent 50-689 part.
3. weeding drug combination preparation as claimed in claim 2 it is characterised in that：Described auxiliary agent includes 10-500 weight
The filler of part.
4. weeding drug combination preparation as claimed in claim 3 it is characterised in that：Described auxiliary agent also includes 10-200 weight
The adhesive of amount part.
5. the weeding drug combination preparation as described in claim 3 or 4 it is characterised in that：Described filler is kieselguhr, swollen
One of profit soil, Kaolin, attapulgite, clay, white carbon, precipitated calcium carbonate and Pulvis Talci or more than one combination.
6. weeding drug combination preparation as claimed in claim 4 it is characterised in that：Described adhesive be cellulose and its
One of modifier, starch and its modifier, animal glue, polyvinyl acetate and sodium silicate or more than one combination.
7. weeding drug combination preparation as claimed in claim 2 it is characterised in that：Described auxiliary agent also includes 100-400
The solvent of weight portion.
8. weeding drug combination preparation as claimed in claim 7 it is characterised in that：Described auxiliary agent also includes 10-50 weight
In amount part cosolvent, the surfactant of 10-200 weight portion, the defoamer of 10-50 weight portion, 10-100 weight portion antifreezing agent
One or more combination.
9. weeding drug combination preparation as claimed in claim 8 it is characterised in that：Described solvent is N, N- dimethyl pyrazole
One of pyrrolidone, ethanol, cyclohexanone, isopropanol, dichloromethane, hexamethylene, chloroform and purified water or more than one group
Close；Described cosolvent is one of Oleic acid glyceryl ester, acetamide, glycerol, Polyethylene Glycol, propylene glycol and glycerol or a kind of
Above combination.
10. weeding drug combination preparation as claimed in claim 8 it is characterised in that：Described surfactant is Hard Fat
Acid, sodium laureth sulfate, dodecylbenzene sodium sulfonate, dodecyl phenenyl sulfate, sodium butylnaphthalenesulfonate, lignin sulfonic acid
Sodium, sodium methylene bis-naphthalene sulfonate, calcium lignosulfonate, polyethers ichthyodin, polyoxyethylene fatty alkyl ether sulfonate, alkanolamide gather
Oxygen vinyl Ether sodium sulfonate, calcium dodecyl benzene sulfonate, alkyl poly glucoside, alkylaryl polyoxyethylene polyoxypropylene ether again, phenethyl
One of phenol polyethenoxy ether, alkylphenol polyoxyethylene, fatty glyceride and Polysorbate or more than one combination.
11. weeding drug combination preparations as claimed in claim 8 it is characterised in that：Described defoamer is isooctanol, has
One of organic siloxane, emulsified silicone oil and polypropylene glycerol aether or more than one combination.
12. weeding drug combination preparations as claimed in claim 8 it is characterised in that：Described antifreezing agent be ethylene glycol, third
One of glycol, butyl glycol ether and carbamide or more than one combination.
13. weeding pharmaceutical compositions as claimed in claim 1 are in preventing and treating Herba Imperatae, Bermuda grass, Herba Digitariae, ferrum awn winnow basket, SANYE Bidens bipinnata
Application in grass.
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| CN201410556822.8A CN104322552B (en) | 2014-10-20 | 2014-10-20 | A kind of weeding pharmaceutical composition and its preparation |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410556822.8A CN104322552B (en) | 2014-10-20 | 2014-10-20 | A kind of weeding pharmaceutical composition and its preparation |
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| CN104322552A CN104322552A (en) | 2015-02-04 |
| CN104322552B true CN104322552B (en) | 2017-03-01 |
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Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105993801A (en) * | 2016-06-22 | 2016-10-12 | 山东省潍坊市农业科学院 | Vigorous cultivation method for syringa vulgaris |
| CN107114400A (en) * | 2017-06-29 | 2017-09-01 | 广西壮族自治区化工研究院 | A kind of herbicidal composition |
| CN112616841A (en) * | 2021-01-07 | 2021-04-09 | 广西三晶化工科技有限公司 | Weeding composition containing picloram, glyphosate and imazapic |
Citations (5)
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|---|---|---|---|---|
| CN1044206A (en) * | 1988-12-30 | 1990-08-01 | 孟山都公司 | Improved glyphosate formulation |
| CN1514686A (en) * | 2001-02-14 | 2004-07-21 | ������ɽ���� | Coformulation of oil-soluble herbicide and water-soluble heribcide as stable oil-in-water emulsion or microemulsion |
| WO2007101587A1 (en) * | 2006-03-06 | 2007-09-13 | Isagro Ricerca S.R.L. | New synergistic herbicidal compositions |
| CN102715174A (en) * | 2012-06-28 | 2012-10-10 | 永农生物科学有限公司 | Compound pesticide composition containing picloram or salts thereof, preparation and application |
| CN103120182A (en) * | 2012-12-26 | 2013-05-29 | 广西三晶化工科技有限公司 | Weedicide composition containing glyphosate, fluroxypyr-meptyl and carfentrazone-ethyl |
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2014
- 2014-10-20 CN CN201410556822.8A patent/CN104322552B/en active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1044206A (en) * | 1988-12-30 | 1990-08-01 | 孟山都公司 | Improved glyphosate formulation |
| CN1514686A (en) * | 2001-02-14 | 2004-07-21 | ������ɽ���� | Coformulation of oil-soluble herbicide and water-soluble heribcide as stable oil-in-water emulsion or microemulsion |
| WO2007101587A1 (en) * | 2006-03-06 | 2007-09-13 | Isagro Ricerca S.R.L. | New synergistic herbicidal compositions |
| CN102715174A (en) * | 2012-06-28 | 2012-10-10 | 永农生物科学有限公司 | Compound pesticide composition containing picloram or salts thereof, preparation and application |
| CN103120182A (en) * | 2012-12-26 | 2013-05-29 | 广西三晶化工科技有限公司 | Weedicide composition containing glyphosate, fluroxypyr-meptyl and carfentrazone-ethyl |
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