CN103960268B - A kind of containing Oxadiargyl with the Herbicidal combinations of orthosulfamuron - Google Patents

Abstract

The present invention relates to a kind of containing Oxadiargyl with the Herbicidal combinations of orthosulfamuron, its effective ingredient is Oxadiargyl and orthosulfamuron, the weight ratio of the two be 10:1～1:10, more ratio of greater inequality be 5:1～1:3.Described Oxadiargyl and orthosulfamuron weight summation percentage by weight in composition pesticide are 0.1%～85%.This Herbicidal combinations has synergistic function, significantly improve herbicidal effect compared with being used alone with single dose, expand weed control spectrum, reduce Pesticide use amount simultaneously, alleviate the pollution to environment, delayed the generation of herbicide resistance, be mainly used in rice terrace preventing and treating annual grassy weeds.

Description

A kind of containing Oxadiargyl with the Herbicidal combinations of orthosulfamuron

Technical field

The present invention relates to pesticide Herbicidal combinations and application thereof, specifically a kind of with propine Oxadiazon and orthosulfamuron are the Herbicidal combinations of effective ingredient, are applied to rice terrace annual grassy weeds Preventing and treating.

Background technology

Oxadiargyl (oxadiargyl): belong to diazole type herbicides, the mechanism of action is former porphin The former oxidasic inhibitor of quinoline.Can be used for rice field and prevent and kill off annual gramineae, Cyperaceae and broad leaved weed And some perennial weeds.

Orthosulfamuron (orthosulfamuron): belong to sulfonylurea herbicide, the mechanism of action is Inhibitor of acetolactate synthetase, stops the synthesis of plant branched-chain amino acid, thus stops weeds albumen The synthesis of matter, makes weeds cell division stop, and last weeds are withered.Be mainly used in rice field prevent and kill off barnyard grass, Dried tuber and broad leaved weed.

By the screening of different pesticide species compounded formulas, filter out rational formula, can be effectively improved Actual prevention effect to disease pest and weed, expanding prevention is composed, and reduces dosage, reduces cost, alleviates Pollution to environment, delays the drug-fast generation of disease pest and weed, is agriculturally disease pest and weed comprehensive control Important means.

The compounding use of Oxadiargyl and orthosulfamuron is conducted in-depth research by the present inventor, On the basis of the screening of substantial amounts of formula indoor and field medicine effect test, find Oxadiargyl and phonetic aniline Sulphur is grand to be compounded, and shows rice terrace annual grassy weeds substantially in the range of certain compound proportion Synergistic function, after further study, complete the present invention.

The most not yet find the relevant report that Oxadiargyl is compounding with orthosulfamuron.

Summary of the invention

It is an object of the invention to provide one to there is synergistic function, expansion weed control spectrum, use into This low, good removing containing the rice terrace that effective ingredient is Oxadiargyl and orthosulfamuron of prevention effect Grass compositions.

The technical scheme realizing the object of the invention is: Herbicidal combinations of the present invention is with Oxadiargyl and phonetic The grand weight ratio for effective ingredient, Oxadiargyl and orthosulfamuron of aniline sulphur is 10:1～1:10, More ratio of greater inequality is 5:1～1:3.Oxadiargyl and orthosulfamuron weight summation are in composition pesticide Percentage by weight is 0.1%～85%, and remaining is to allow in pesticide to use and acceptable auxiliary element.

Herbicidal combinations of the present invention can be processed into oil according to well known to a person skilled in the art method Suspending agent, granule, wettable powder, water dispersible granules, effervescent tablet, aqueous emulsion and exhibition film oil The application forms used in the applicable agricultural production such as agent.

Described oil-suspending agent dosage form weight percent consists of: Oxadiargyl 1～40%, phonetic aniline Sulphur grand 1～40%, dispersant 5～15%, wetting agent 5-15%, thickening agent 0.1～2%, liquid-carrier Complement to 100%.Concrete production stage is: mix, effective ingredient and other auxiliary agent through high speed shear In dispersion, sand mill after sand milling, non-water-medium forms high dispersive, stable suspension system, Prepare oil-suspending agent.

Described dosage form of water dispersible granule weight percent consists of: Oxadiargyl 1～60%, phonetic benzene Amine sulphur grand 1～60%, dispersant 5～15%, wetting agent 5～10%, disintegrating agent 1～10%, solid carries Body complements to 100%.Concrete production stage is: by effective ingredient and other auxiliary agent mix homogeneously, with super Tiny pore pulverizer is pulverized, and through mediating, is subsequently adding in fluidized-bed granulation dryer and carries out pelletize, dry Dry, screening, prepares water dispersible granules.

Described wettable powder formulation weight percent consists of: Oxadiargyl 1～60%, phonetic benzene Amine sulphur grand 1～60%, dispersant 5～15%, wetting agent 5～15%, solid carrier complements to 100%. Concrete production stage is: effective ingredient and other auxiliary agent are mixed, again through comminution by gas stream after mechanical activation comminution, Mix homogeneously, prepares wettable powder.

Described granule dosage form weight percent consists of: Oxadiargyl 0.1～10%, phonetic aniline Sulphur grand 0.1～10%, binding agent 10～30%, dispersant 5～15%, wetting agent 5～10%, solid carries Body complements to 100%.Concrete production stage is: by effective ingredient and the blended kneading that adds water of other auxiliary agent, Use pinch-out granulator pinch out and shape, afterwards by granule fluid bed drying, screening, prepare granule Agent.

Described effervescent tablet dosage form weight percent consists of: Oxadiargyl 0.1～30%, phonetic benzene Amine sulphur grand 0.1～30%, dispersant 5～15%, wetting agent 5～10%, solid acid 10～30%, carbonic acid Salt 10～30%, binding agent 1～10%, flowing regulator 1～10%, solid carrier complements to 100%. By abundant to effective ingredient, wetting agent, dispersant, solid acid, carbonate, flowing regulator and filler Mix homogeneously, is then crushed to 0.3～5 μm with superfine comminution at low temperature machine, is subsequently added into and sticks with paste with water furnishing The binding agent of shape, uses tablet machine film-making after stirring, last drying, granulate, detect, seal After packaging, prepare effervescent tablet.

Described aqueous emulsion agent weight percent consists of: Oxadiargyl 1～40%, phonetic aniline sulphur Grand 1～40%, emulsifying agent 5～30%, solvent 5～15%, antifreezing agent 2～5%, defoamer 0.1～5%, Thickening agent 0.1～2%, deionized water complements to 100%.First effective ingredient, solvent, emulsifying agent are mixed It is combined, dissolves and become uniform oil phase.Again part water and other auxiliary agents are mixed, molten Solution becomes uniform aqueous phase.While high-speed stirred, aqueous phase is added oil phase the most in a kettle., slow Slowly add water to reach phase inversion point, carry out high speed shear afterwards, and add remaining water, shear about 30min, Prepare aqueous emulsion.

Described film-spreading oil solution dosage form weight percent consists of: Oxadiargyl 1～40%, phonetic aniline Sulphur grand 1～40%, solvent 1～20%, film former 1～20%, dispersant 1～15%, liquid-carrier is mended Foot is to 100%.After fully being dissolved by effective ingredient solvent, it is initially charged dispersant, is eventually adding film forming Agent, is thoroughly mixed uniformly to transparent, prepares film-spreading oil solution.

Described solvent can be methanol, ethanol, butanol, propylene glycol, glycerol, Polyethylene Glycol, Ketohexamethylene, ketopyrrolidine, machine oil, solvent naphtha, trimethylbenzene, dimethylbenzene, dimethylformamide, nitrogen Methyl pyrrolidone, fatty acid distribution of coconut oil methyl ester, methyl oleate, methylated vegetable oil, ethyl acetate, One or more in dimethyl phthalate, dibutyl phthalate etc..

Described emulsifying agent can be alkylphenol polyoxyethylene, alkylphenol-polyethenoxy polyethenoxy ether, Ben-zylphenol Polyoxyethyl Ether, polyoxyethylene fatty acid ester, polyoxyethylene aliphatic alcohol ether, polyoxyethylene fat Fat amine, alkyl phenol polyglycol ether, Span series (sorbitan monostearate), TWEEN Series (lose Water Span polyoxyethylene ether), AEO series (fat alcohol polyoxyethylenated alcohol), OP series Phosphate ester (thermally coupled distillation columns), OP serial (NPE), By system One or more in row (castor oil polyoxyethylene ether) etc..

Described film former can be Lauryl Alcohol ester, methyl laurate, octadecanol, propylene glycol phenylate And one or more in monobutyl ether acetate etc..

Described defoamer can be in silicone compound, epoxy soybean oil, methanol, silicone oil etc. One or more.

Described antifreezing agent can be one or more in glycerol, propylene glycol, diethylene glycol, carbamide etc..

Described wetting agent can be sodium lauryl sulphate, dodecylbenzene sodium sulfonate, dibutyl naphthalene sulphur One or more in acid sodium, sodium alkyl sulfonate, tea seed cake powder, spaonin powder, Fructus Sapindi Mukouossi powder etc..

Described dispersant can be alkylphenol polyoxyethylene formaldehyde condensation products, naphthalene sulphonate formaldehyde contracting Compound, to methoxyl group fatty acyl anilinesulfonic acid, lignosulfonates, polycarboxylate, alkyl phenol gather Oxygen vinyl Ether sulfate, alkyl benzene sulfonate calcium salt, fatty acid ester sulfate, alkylphenol polyoxyethylene, One or more in fatty alcohol-polyoxyethylene ether etc..

Described disintegrating agent can be carboxymethyl starch sodium, low-substituted hydroxypropyl cellulose, crosslinking carboxylic first Base sodium cellulosate, polyvinylpolypyrrolidone, chitosan, sodium alginate sodium bicarbonate, magnesium chloride, aluminum chloride, One or more in sodium chloride, carbamide, ammonium sulfate, bentonite etc..

Described thickening agent can be polyvinyl acetate, xanthan gum, gelatin, Radix Acaciae senegalis, silicon One or more in acid magnalium, phenolic resin, hydroxymethyl cellulose, sodium alginate etc..

Described solid carrier can be precipitated calcium carbonate, potter's clay, Kaolin, kieselguhr, bentonite, One or more in white carbon, clay, attapulgite, Pulvis Talci, quartz sand etc..

Described liquid-carrier can be exquisite soybean oil, Semen Maydis oil, Oleum Brassicae campestris, Oleum Terebinthinae, oleic acid One or more in methyl ester, Oleum Cocois, Petiolus Trachycarpi oil etc..

Described binding agent can be sucrose, polyvinyl alcohol, Polyethylene Glycol, sodium carboxymethyl cellulose, Carboxymethylcellulose calcium, carboxy-propyl cellulose, dextrin, amylodextrin, polyvinylpyrrolidone, viscous One or more in property Kaolin, paraffin, Colophonium etc..

Described solid acid can be citric acid, succinic acid, maleic acid, fumaric acid, tartaric acid, grass Acid, malonic acid, malic acid, succinic acid, adipic acid, boric acid, phosphoric acid, benzoic acid, sulfamic acid, One or more in salicylic acid, glutamic acid, phenylacetic acid, nicotinic acid or sorbic acid etc..

Described carbonate can be sodium carbonate, potassium carbonate, ammonium carbonate, calcium carbonate, lithium carbonate, carbon Acid hydrogen sodium, potassium bicarbonate, lithium bicarbonate, sodium sesquicarbonate, bicarbonate tripotassium or bicarbonate three ammonium etc. In one or more.

Described flowing regulator can be calcium stearate, magnesium stearate, barium stearate, titanium dioxide, In Pulvis Talci, Stepanol MG, polysorbate, Semen Tritici aestivi starch or sodium benzoate etc. a kind of or Several.

The frequency of administration of the present composition and amount of application with crops, weeds, weather condition change and There is small variations, can reach, by using suitable dosage, the purpose effectively prevented and treated.

Compared with prior art, it is an advantage of the current invention that:

1, Oxadiargyl and orthosulfamuron compounding have synergistic function, individually make than single dose With significantly improving the prevention effect to paddy field weed, expand weed control spectrum.

2, Oxadiargyl and two kinds of effective ingredient of orthosulfamuron compound, decrease Pesticide use amount, Reduce resistance risk, to decrease use cost, Environmental compatibility good.

Detailed description of the invention

In order to be more fully understood that the essence of the present invention, below in conjunction with embodiment present disclosure made into One step explanation, but limitation of the present invention can not be considered as.

(1) Formulation Example.

In following examples, effective ingredient uses the 96% former medicine of Oxadiargyl and 98% orthosulfamuron Former medicine, each component percentages is weight percentage.

Embodiment 1:65% Oxadiargyl orthosulfamuron water dispersible granules.

Oxadiargyl 40%, orthosulfamuron 25%, sodium lauryl sulphate 5%, to methoxyl group fat Fat amide groups benzenesulfonic acid 8%, ammonium sulfate 2%, Kaolin supplies 100%.By above-mentioned effective ingredient, divide Powder, wetting agent, disintegrating agent and solid carrier mix homogeneously, pulverize with micro jet, warp Mediate, be subsequently adding in fluidized-bed granulation dryer and carry out pelletize, dry, screening, can be prepared by 65% Oxadiargyl orthosulfamuron water dispersible granules.

Embodiment 2:70% Oxadiargyl orthosulfamuron wettable powder.

Oxadiargyl 40%, orthosulfamuron 30%, sodium butylnaphthalenesulfonate 6%, fatty acid ester sulphuric acid Salt 8%, kieselguhr supplies 100%.By above-mentioned by effective ingredient, dispersant, wetting agent and solid carrier Mixing, again through comminution by gas stream, mix homogeneously after mechanical activation comminution, can be prepared by 70% Oxadiargyl phonetic The grand wettable powder of aniline sulphur.

Embodiment 3:20% Oxadiargyl orthosulfamuron oil-suspending agent.

Oxadiargyl 12%, orthosulfamuron 8%, polycarboxylate 10%, dodecylbenzene sodium sulfonate 10%, sodium alginate 1.5%, methyl oleate supplies 100%.By above-mentioned effective ingredient and auxiliary agent through at a high speed Shear in dispersion, sand mill after sand milling, the high dispersive formed in non-water-medium, stable suspension System, can be prepared by 20% Oxadiargyl orthosulfamuron oil-suspending agent.

Embodiment 4:1% Oxadiargyl orthosulfamuron granule.

Oxadiargyl 0.7%, orthosulfamuron 0.3%, sodium butylnaphthalenesulfonate 10%, lignin sulfonic acid Salt 10%, polyvinyl alcohol 20%, clay complements to 100%.By blended to above-mentioned effective ingredient and auxiliary agent Add water and mediate, use pinch-out granulator pinch out and shape, afterwards by granule fluid bed drying, Screening, can be prepared by 1% Oxadiargyl orthosulfamuron granule.

Embodiment 5:35% Oxadiargyl orthosulfamuron effervescent tablet.

Oxadiargyl 20%, orthosulfamuron 15%, sodium lauryl sulphate 5%, fatty alcohol polyoxy Vinyl Ether 5%, tartaric acid 15%, potassium bicarbonate 15%, dextrin 2%, magnesium stearate 5%, Kaolin is mended Foot is to 100%.Above-mentioned effective ingredient and other auxiliary agent (except binding agent) are sufficiently mixed uniformly, so It is crushed to 0.3～5 μm with superfine comminution at low temperature machine afterwards, is subsequently added into the binding agent using water furnishing pasty state, Use tablet machine film-making after stirring, last drying, granulate, detect, pack after, Prepare 35% Oxadiargyl orthosulfamuron effervescent tablet.

Embodiment 6:40% Oxadiargyl orthosulfamuron aqueous emulsion.

Oxadiargyl 25%, orthosulfamuron 15%, castor oil polyoxyethylene ether 20%, Ketohexamethylene 10%, Propylene glycol 2%, silicone oil 0.5%, xanthan gum 0.2%, deionized water complements to 100%.First will effectively become Divide, solvent, emulsifying agent mix, and dissolve and become uniform oil phase.Again by part water and other Auxiliary agent mixes, and dissolves and becomes uniform aqueous phase.The most in a kettle. while high-speed stirred Aqueous phase is added oil phase, slowly adds water to reach phase inversion point, carry out high speed shear afterwards, and add surplus Remaining water, shears about 30min, can be prepared by 40% Oxadiargyl orthosulfamuron aqueous emulsion.

Embodiment 7:10% Oxadiargyl orthosulfamuron film-spreading oil solution.

Oxadiargyl 5%, orthosulfamuron 5%, Ketohexamethylene 5%, Lauryl Alcohol ester 10%, alkyl phenol Polyoxyethylene ether 5%, NPE 10%, ethyl acetate complements to 100%.To effectively become After demultiplexing solvent fully dissolves, it is initially charged dispersant, is eventually adding film former, be thoroughly mixed all Even to transparent, can be prepared by 10% Oxadiargyl orthosulfamuron film-spreading oil solution.

(2) indoor biological determination of activity embodiment.

Reagent agent: the 96% former medicine of Oxadiargyl and the former medicine of 95% orthosulfamuron.

For examination target: Herba monochoriae vaginalis (Monochoria vaginalis), barnyard grass (Echinochloa Crusgalli), Herba Cyperi Difformis (Cyperus difformis).

Medicament configuration design: Oxadiargyl single dose is configured to 10,25,40g a.i./ha solution standby With；Orthosulfamuron single dose is configured to 8,19,30g a.i./ha solution for standby；Oxadiargyl and Orthosulfamuron mixture be configured to 10+8,10+19,10+30,25+8,25+19,25+30,40+8, 40+19,40+30g a.i./ha solution for standby.

Test method: the built-in quantitative soil of polypots at high 6cm, diameter 9cm, will be miscellaneous for examination target Grass seed 15～20 sowings, in polypots, are trained in being placed on greenhouse after the thick fine earth of lid 0.5～1cm Support, treat that weeds length to the 1～2 leaf phases carry out stem and leaf spraying treatment, every alms bowl spraying liquid 1mL, often process weight Multiple 4 times, and set the process without medicament as compareing.Try material after process and be placed in temperature indoor cultivation, periodically Observe the growing state of target weeds, after 20d, estimate target damage symptoms and growth inhibited situation, and Claim aerial parts fresh weight, evaluate the medicament toxicity action to target weeds with target fresh weight inhibition.

Investigation method: test estimates target damage symptoms and growth inhibited situation after processing 20d, and claims Aerial parts fresh weight, calculates fresh weight inhibition (%).

Synergy evaluation methodology: evaluate herbicide associated form (NY/T according to Gowing method 1155.7-2006), its formula is as follows:

E₀X Y XY/100.

In formula, X is Oxadiargyl with certain dosage fresh weight inhibition to target weeds time alone；Y is phonetic benzene Amine sulphur grand with certain dosage fresh weight inhibition to target weeds time alone；E₀For Oxadiargyl, phonetic benzene Theoretical value to target weeds fresh weight inhibition during the grand two kinds of pharmacy mix of amine sulphur；E be Oxadiargyl, Measured value to target weeds fresh weight inhibition during two kinds of pharmacy mix of orthosulfamuron.

Evaluation criterion: as E E₀During ＞ 10%, it is expressed as potentiation；As 10%≤E E₀When≤10%, show as summation action；As E E₀During ＜ 10%, show as antagonism.

Table 1, each chemicals treatment Toxicity Determination to Herba monochoriae vaginalis.

Table 2, each chemicals treatment Toxicity Determination to barnyard grass.

Table 3, each chemicals treatment Toxicity Determination to Herba Cyperi Difformis.

By the Toxicity Determination result of table 1, table 2 and table 3 it can be seen that Oxadiargyl and phonetic The grand mixture of aniline sulphur respectively processes the E-E to Herba monochoriae vaginalis, barnyard grass and Herba Cyperi Difformis₀(%) value is all higher than 10%, Illustrate that three is compounding and Herba monochoriae vaginalis, barnyard grass and Herba Cyperi Difformis are had synergistic function.As can be seen here, Oxadiargyl and orthosulfamuron mixture have reasonability and feasibility.

(3) field efficacy checking embodiment.

Herba monochoriae vaginalis, barnyard grass and Herba Cyperi Difformis is experimental field selected to occur more transplanted rice field to carry out.Examination Testing and set 4 process altogether, often process and set 3 repetitions, processing 1 is the 20% phonetic aniline of Oxadiargyl The grand oil-suspending agent of sulphur (12:8), to process 2 be 80% Oxadiargyl wettable powder, process and 3 be 50% orthosulfamuron water dispersible granules, process 4 are comparison (not dispenser not weeding), 30 days systems after medicine Count each process number of weeds amount and calculate preventive effect.

Table 4, each chemicals treatment prevent and kill off the field control effectiveness test result of transplanted rice field annual grassy weeds.

By the field test results of table 4 it can be seen that the 30 days 20% phonetic aniline of Oxadiargyl after medicine When sulphur grand oil-suspending agent (12:8) usage amount is 50-60g a.i./ha to transplanted rice field barnyard grass, The preventive effect of Herba monochoriae vaginalis and Herba Cyperi Difformis is all substantially higher and is used alone in each single dose, simultaneously at test survey During do not find 20% Oxadiargyl orthosulfamuron oil-suspending agent (12:8) to Oryza sativa L. produce Poisoning.As can be seen here, said composition is worth popularization and application in agricultural production.

Claims (3)

1. one kind contains Oxadiargyl and the Herbicidal combinations of orthosulfamuron, it is characterised in that: effective ingredient is Oxadiargyl and orthosulfamuron, and the weight ratio of the two is 5:1～1:3, described Oxadiargyl and orthosulfamuron weight summation percentage by weight in composition pesticide are 0.1%～85%.

It is the most according to claim 1 a kind of containing Oxadiargyl with the Herbicidal combinations of orthosulfamuron, it is characterised in that: the dosage form of described Herbicidal combinations is the one in oil-suspending agent, granule, wettable powder, water dispersible granules, effervescent tablet, aqueous emulsion or film-spreading oil solution.

3. a kind of Herbicidal combinations containing Oxadiargyl and orthosulfamuron described in claim 1 is in the application prevented and kill off on rice terrace annual grassy weeds.