CN104321336B - 管理哺乳的肽 - Google Patents

管理哺乳的肽 Download PDF

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Publication number
CN104321336B
CN104321336B CN201380025974.9A CN201380025974A CN104321336B CN 104321336 B CN104321336 B CN 104321336B CN 201380025974 A CN201380025974 A CN 201380025974A CN 104321336 B CN104321336 B CN 104321336B
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China
Prior art keywords
pharmaceutical composition
seq
peptide
synthetic
amino acid
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Application number
CN201380025974.9A
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English (en)
Chinese (zh)
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CN104321336A (zh
Inventor
乔斯·马里奥·伊斯柯维奇
贾维尔·伊斯柯维奇
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Mileutis Ltd
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Mileutis Ltd
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Publication of CN104321336A publication Critical patent/CN104321336A/zh
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/07—Tetrapeptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/14—Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4732—Casein
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1019—Tetrapeptides with the first amino acid being basic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Oncology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Communicable Diseases (AREA)
  • Gynecology & Obstetrics (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
CN201380025974.9A 2012-03-19 2013-03-08 管理哺乳的肽 Active CN104321336B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261612410P 2012-03-19 2012-03-19
US61/612,410 2012-03-19
PCT/IL2013/050214 WO2013140388A1 (en) 2012-03-19 2013-03-08 Peptides for management of lactation

Publications (2)

Publication Number Publication Date
CN104321336A CN104321336A (zh) 2015-01-28
CN104321336B true CN104321336B (zh) 2021-08-06

Family

ID=49221927

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201380025974.9A Active CN104321336B (zh) 2012-03-19 2013-03-08 管理哺乳的肽

Country Status (11)

Country Link
US (1) US9487557B2 (https=)
EP (1) EP2828281B1 (https=)
JP (1) JP6426599B2 (https=)
CN (1) CN104321336B (https=)
AU (1) AU2013236975B2 (https=)
BR (1) BR112014023087A8 (https=)
CA (1) CA2867557C (https=)
ES (1) ES2759980T3 (https=)
IL (1) IL234574B (https=)
IN (1) IN2014DN08610A (https=)
WO (1) WO2013140388A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102022118B1 (ko) * 2019-01-07 2019-09-18 주식회사 아스트로젠 중추신경계 질환의 예방 또는 치료용 세린 유도체 화합물
CN111632128B (zh) * 2019-02-14 2022-07-05 三凡生技研发股份有限公司 短链胜肽组合物在预防或治疗干眼症的应用
EP4064854A1 (en) 2019-11-28 2022-10-05 Boehringer Ingelheim Vetmedica GmbH Use of sglt-2 inhibitors in the drying-off of non-human mammals
US20240207352A1 (en) * 2021-04-28 2024-06-27 Mileutis Ltd. Compositions and methods for modulating mammary disorders and conditions

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101247721A (zh) * 2005-05-02 2008-08-20 米勒尤迪斯公司 包括酪蛋白衍生肽的药物组合物及其使用方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6391849B1 (en) 1999-11-19 2002-05-21 Agricultural Research Organization, The Volcani Center Method and pharmaceutical composition for disrupting lactation in a mammary gland and for treating and preventing mastitis
US20050220801A1 (en) * 2001-03-09 2005-10-06 Hajime Otani Immunopotentiators
US7968513B2 (en) 2005-05-02 2011-06-28 Mileutis Ltd. Pharmaceutical compositions comprising casein derived peptides and methods of use thereof
JP2010536341A (ja) * 2007-08-15 2010-12-02 アムニクス， インコーポレイテッド 生物学的に活性なポリペプチドの特性を改変するための組成物および方法

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101247721A (zh) * 2005-05-02 2008-08-20 米勒尤迪斯公司 包括酪蛋白衍生肽的药物组合物及其使用方法

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
Alpha-s2-casein precursor-goat，GenBank Acc#JN0547;Bouniol C et al;《GenBank》;19991015;全文 *
Alpha-s2-casein precursor-sheep，GenBank Acc#KASH2;Boisnard M et al;《GenBank》;19990622;全文 *
Boisnard M et al.Alpha-s2-casein precursor-sheep，GenBank Acc#KASH2.《GenBank》.1999,全文. *
Bouniol C et al.Alpha-s2-casein precursor-goat，GenBank Acc#JN0547.《GenBank》.1999,全文. *

Also Published As

Publication number Publication date
US20150093400A1 (en) 2015-04-02
AU2013236975A1 (en) 2014-10-23
IL234574B (en) 2020-09-30
CA2867557C (en) 2020-03-10
JP2015516377A (ja) 2015-06-11
US9487557B2 (en) 2016-11-08
CA2867557A1 (en) 2013-09-26
BR112014023087A2 (pt) 2017-06-20
EP2828281A4 (en) 2015-11-11
AU2013236975B2 (en) 2017-10-19
BR112014023087A8 (pt) 2018-01-16
EP2828281B1 (en) 2019-09-18
CN104321336A (zh) 2015-01-28
IN2014DN08610A (https=) 2015-05-22
WO2013140388A1 (en) 2013-09-26
ES2759980T3 (es) 2020-05-12
JP6426599B2 (ja) 2018-11-21
EP2828281A1 (en) 2015-01-28

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