CN104306921A - Rhizoma zingiberis cough-relieving and sputum-reducing oral liquid and preparation method thereof - Google Patents
Rhizoma zingiberis cough-relieving and sputum-reducing oral liquid and preparation method thereof Download PDFInfo
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- CN104306921A CN104306921A CN201410519588.1A CN201410519588A CN104306921A CN 104306921 A CN104306921 A CN 104306921A CN 201410519588 A CN201410519588 A CN 201410519588A CN 104306921 A CN104306921 A CN 104306921A
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- A—HUMAN NECESSITIES
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/076—Poria
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/26—Aristolochiaceae (Birthwort family), e.g. heartleaf
- A61K36/268—Asarum (wild ginger)
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/27—Asclepiadaceae (Milkweed family), e.g. hoya
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/57—Magnoliaceae (Magnolia family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/79—Schisandraceae (Schisandra family)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9068—Zingiber, e.g. garden ginger
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- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
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Abstract
The invention discloses a rhizoma zingiberis cough-relieving and sputum-reducing oral liquid and a preparation method thereof. The rhizoma zingiberis cough-relieving and sputum-reducing oral liquid is prepared by taking 13-15% of rhizoma zingiberis as monarch drug, 5-7% of asarum, 15-17% of schisandra chinensis, 18-20% of poria cocos, 13-15% of aster, 10-12% of flos farfarae, 8-10% of cynanchum glaucescens and 10-12% of radix glycyrrhizae preparata as raw materials through steps of decocting, poaching, filtering, concentrating, burdening and packaging. The rhizoma zingiberis cough-relieving and sputum-reducing oral liquid has efficacies of removing dampness to reduce phlegm, and astringing lung to stop cough, can effectively treat various discomforts caused by cough, has the advantages of quick response, short course of treatment, and no side effect, and the total effective rate can achieve 100%.
Description
Technical field
The present invention relates to the technical field of Chinese patent medicine, espespecially a kind of Rhizoma Zingiberis relieving cough and resolving phlegm oral liquid and preparation method thereof.
Background technology
Cough is a kind of guarding reflex action of human body, and be the reflection that human body is removed secretions in respiratory tract or foreign body protectiveness and breathed, the pathological discharge thing in respiratory tract and the foreign body entered from the external world in respiratory tract, can borrow the action of coughre flex and excrete.Although its favourable one side can be had, as being irritable cough frequently and cause the work of impact and rest, then lose its protectiveness meaning.
Use cough syrup is generally searched in traditional treatment cough, but such medicine has dependency, should not apply in a short time too much, easily cause the side effect such as tachycardia; The result that the human experimentation that Chinese medicine is through several thousand draws, simultaneously just on the books from Huang di's Canon of Medicine to the understanding of cough, although treatment by Chinese herbs cough can treating both the principal and secondary aspects of a disease, and side effect is little.But Chinese medicine is in use more loaded down with trivial details, needs to decoct processing, bring many inconvenience to patient.
Summary of the invention
A kind of Rhizoma Zingiberis relieving cough and resolving phlegm of the present invention oral liquid and preparation method thereof, the deficiency of above-mentioned technology can be solved, employing Rhizoma Zingiberis is monarch drug, is aided with Herba Asari, Fructus Schisandrae Chinensis, Poria, Radix Asteris, Flos Farfarae, Rhizoma Cynanchi Stauntonii, Radix Glycyrrhizae Preparata 7 taste Chinese medicine, prepare oral liquid through decoction, decocting in water, filtration, concentrated, batching, packaging step, realize the object of quick relieving cough and resolving phlegm.
To achieve these goals, technical solution of the present invention is: the Chinese medicinal components of a kind of Rhizoma Zingiberis relieving cough and resolving phlegm oral liquid and preparation method thereof: Rhizoma Zingiberis 13% ~ 15%, Herba Asari 5% ~ 7%, Fructus Schisandrae Chinensis 15% ~ 17%, Poria 18% ~ 20%, Radix Asteris 13% ~ 15%, Flos Farfarae 10% ~ 12%, Rhizoma Cynanchi Stauntonii 8% ~ 10%, Radix Glycyrrhizae Preparata 10% ~ 12%.
Preparation process is as follows:
(1) decoct: use cold water soak after Chinese medicinal components fragmentation, within every 8 hours, change water once, after bubble to the saturating heart, 8 times amount that add water decoct secondary, first time 3h, second time 2h; Merge decoction liquor, for subsequent use;
(2) filter: decoction liquor 200 eye mesh screens are filtered, leave standstill 48 hours, get supernatant for subsequent use.
(3) concentrate: filtrate is inserted in vacuum concentration pot, setting concentration tank vacuum degree control is at 0.065MPa, and Steam pressure control, at 0.2 Mpa, is condensed into concentrated extract;
(4) prepare burden: added by concentrated extract in material-compound tank, add 500 times of pure water dilution stirrings after 20 minutes, heated and boiled, keeps slight boiling condition 30 minutes, with 0.8 μm of aperture titanium rod pressure filtration, leaves standstill and put to temperature less than 20 DEG C under air-tight state;
(5) pack: after adopting oral liquid packer to carry out packaging sterilization, to obtain final product.
The effect of Chinese medicinal components of the present invention and effect: Rhizoma Zingiberis acrid in the mouth is hot in nature, return through spleen lung, can damp eliminating.Again can dissipating fluid-retention, spleen lung is ruled together as monarch drug; Herba Asari lung qi dispersing cold expelling, Fructus Schisandrae Chinensis astringing lung-QI and relieving cough, two medicine compatibilities, can recover the function that lungs a surname sends out respectful to fall and be all ministerial drug; Poria is sweet flatly to be oozed, drying damp and strengthening spleen with the source of producing phlegm of shutting out, then to add Radix Asteris, Flos Farfarae, Rhizoma Cynanchi Stauntonii lung qi dispersing promoting the circulation of QI, preventing phlegm from forming and stopping coughing be adjuvant drug altogether; Radix Glycyrrhizae Preparata gets final product spleen invigorating invigorating middle warmer, again can coordinating the actions of various ingredients in a prescription for making medicine, all medicines can be made to influence each other, and collaborative work altogether, has drying dampness to eliminate phlegm, effect of reason lung cough-relieving, effectively can treat the symptom of the various discomforts caused by cough, there is instant effect, short treating period, the advantage had no side effect, total effective rate can reach 100%.
Detailed description of the invention
Embodiment 1
(1) Chinese medicinal components: Rhizoma Zingiberis 15%, Herba Asari 5%, Fructus Schisandrae Chinensis 15%, Poria 20%, Radix Asteris 15%, Flos Farfarae 10%, Rhizoma Cynanchi Stauntonii 10%, Radix Glycyrrhizae Preparata 10%.
(2) preparation process is as follows:
1. decoct: use cold water soak after Chinese medicinal components fragmentation, within every 8 hours, change water once, after bubble to the saturating heart, 8 times amount that add water decoct secondary, first time 3h, second time 2h; Merge decoction liquor, for subsequent use;
2. filter: decoction liquor 200 eye mesh screens are filtered, leave standstill 48 hours, get supernatant for subsequent use.
3. concentrate: filtrate is inserted in vacuum concentration pot, setting concentration tank vacuum degree control is at 0.065MPa, and Steam pressure control, at 0.2 Mpa, is condensed into concentrated extract;
4. prepare burden: added by concentrated extract in material-compound tank, add 500 times of pure water dilution stirrings after 20 minutes, heated and boiled, keeps slight boiling condition 30 minutes, with 0.8 μm of aperture titanium rod pressure filtration, leaves standstill and put to temperature less than 20 DEG C under air-tight state;
5. pack: after adopting oral liquid packer to carry out packaging sterilization, to obtain final product.
Embodiment 2
(1) Chinese medicinal components: Rhizoma Zingiberis 14%, Herba Asari 6%, Fructus Schisandrae Chinensis 16%, Poria 19%, Radix Asteris 14%, Flos Farfarae 11%, Rhizoma Cynanchi Stauntonii 9%, Radix Glycyrrhizae Preparata 11%.
(2) preparation process is as follows:
1. decoct: use cold water soak after Chinese medicinal components fragmentation, within every 8 hours, change water once, after bubble to the saturating heart, 8 times amount that add water decoct secondary, first time 3h, second time 2h; Merge decoction liquor, for subsequent use;
2. filter: decoction liquor 200 eye mesh screens are filtered, leave standstill 48 hours, get supernatant for subsequent use.
3. concentrate: filtrate is inserted in vacuum concentration pot, setting concentration tank vacuum degree control is at 0.065MPa, and Steam pressure control, at 0.2 Mpa, is condensed into concentrated extract;
4. prepare burden: added by concentrated extract in material-compound tank, add 500 times of pure water dilution stirrings after 20 minutes, heated and boiled, keeps slight boiling condition 30 minutes, with 0.8 μm of aperture titanium rod pressure filtration, leaves standstill and put to temperature less than 20 DEG C under air-tight state;
5. pack: after adopting oral liquid packer to carry out packaging sterilization, to obtain final product.
Embodiment 3
(1) Chinese medicinal components: Rhizoma Zingiberis 13%, Herba Asari 7%, Fructus Schisandrae Chinensis 17%, Poria 18%, Radix Asteris 13%, Flos Farfarae 12%, Rhizoma Cynanchi Stauntonii 8%, Radix Glycyrrhizae Preparata 12%.
(2) preparation process is as follows:
1. decoct: use cold water soak after Chinese medicinal components fragmentation, within every 8 hours, change water once, after bubble to the saturating heart, 8 times amount that add water decoct secondary, first time 3h, second time 2h; Merge decoction liquor, for subsequent use;
2. filter: decoction liquor 200 eye mesh screens are filtered, leave standstill 48 hours, get supernatant for subsequent use.
3. concentrate: filtrate is inserted in vacuum concentration pot, setting concentration tank vacuum degree control is at 0.065MPa, and Steam pressure control, at 0.2 Mpa, is condensed into concentrated extract;
4. prepare burden: added by concentrated extract in material-compound tank, add 500 times of pure water dilution stirrings after 20 minutes, heated and boiled, keeps slight boiling condition 30 minutes, with 0.8 μm of aperture titanium rod pressure filtration, leaves standstill and put to temperature less than 20 DEG C under air-tight state;
5. pack: after adopting oral liquid packer to carry out packaging sterilization, to obtain final product.
Application result:
| Group | Number of cases | Effective | Effectively | Total effective rate |
| Embodiment one | 50 | 47 | 3 | 100% |
| Embodiment two | 50 | 44 | 6 | 100% |
| Embodiment three | 50 | 45 | 5 | 100% |
Apply this product clinical treatment through 150 routine patients, taking rear symptom can well be alleviated, and have no obvious toxic and side effects in application patient, do not find untoward reaction, total effective rate reaches 100%.
The above; embodiment is only be described the preferred embodiment of the present invention; not scope of the present invention is limited; under the prerequisite of spirit not departing from the technology of the present invention; the various distortion that this area engineers and technicians make technical scheme of the present invention and improvement, all should fall in protection domain that claims of the present invention determine.
Claims (2)
1. Rhizoma Zingiberis relieving cough and resolving phlegm oral liquid and preparation method thereof, is characterized in that: Chinese medicinal components is Rhizoma Zingiberis 13% ~ 15%, Herba Asari 5% ~ 7%, Fructus Schisandrae Chinensis 15% ~ 17%, Poria 18% ~ 20%, Radix Asteris 13% ~ 15%, Flos Farfarae 10% ~ 12%, Rhizoma Cynanchi Stauntonii 8% ~ 10%, Radix Glycyrrhizae Preparata 10% ~ 12%.
2. a kind of Rhizoma Zingiberis relieving cough and resolving phlegm oral liquid according to claim 1 and preparation method thereof, is characterized in that: preparation process is as follows:
(1) decoct: use cold water soak after Chinese medicinal components fragmentation, within every 8 hours, change water once, after bubble to the saturating heart, 8 times amount that add water decoct secondary, first time 3h, second time 2h; Merge decoction liquor, for subsequent use;
(2) filter: decoction liquor 200 eye mesh screens are filtered, leave standstill 48 hours, get supernatant for subsequent use;
(3) concentrate: filtrate is inserted in vacuum concentration pot, setting concentration tank vacuum degree control is at 0.065MPa, and Steam pressure control, at 0.2 Mpa, is condensed into concentrated extract;
(4) prepare burden: added by concentrated extract in material-compound tank, add 500 times of pure water dilution stirrings after 20 minutes, heated and boiled, keeps slight boiling condition 30 minutes, with 0.8 μm of aperture titanium rod pressure filtration, leaves standstill and put to temperature less than 20 DEG C under air-tight state;
(5) pack: after adopting oral liquid packer to carry out packaging sterilization, to obtain final product.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410519588.1A CN104306921A (en) | 2014-10-08 | 2014-10-08 | Rhizoma zingiberis cough-relieving and sputum-reducing oral liquid and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410519588.1A CN104306921A (en) | 2014-10-08 | 2014-10-08 | Rhizoma zingiberis cough-relieving and sputum-reducing oral liquid and preparation method thereof |
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| CN104306921A true CN104306921A (en) | 2015-01-28 |
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| CN201410519588.1A Pending CN104306921A (en) | 2014-10-08 | 2014-10-08 | Rhizoma zingiberis cough-relieving and sputum-reducing oral liquid and preparation method thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104857462A (en) * | 2015-04-30 | 2015-08-26 | 刘德刚 | Traditional Chinese medicine capable of relieving cough and reducing sputum |
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- 2014-10-08 CN CN201410519588.1A patent/CN104306921A/en active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104857462A (en) * | 2015-04-30 | 2015-08-26 | 刘德刚 | Traditional Chinese medicine capable of relieving cough and reducing sputum |
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Application publication date: 20150128 |