CN104306854A - Medicine for treating autism and preparation method thereof - Google Patents

Medicine for treating autism and preparation method thereof Download PDF

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CN104306854A
CN104306854A CN201410622090.8A CN201410622090A CN104306854A CN 104306854 A CN104306854 A CN 104306854A CN 201410622090 A CN201410622090 A CN 201410622090A CN 104306854 A CN104306854 A CN 104306854A
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parts
fructus
medicine
pure water
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周晓露
程磊
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WUHAN BOKANGDA TRADE Co Ltd
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WUHAN BOKANGDA TRADE Co Ltd
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/185Magnoliopsida (dicotyledons)
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    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/488Pueraria (kudzu)
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/734Crataegus (hawthorn)
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    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
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Abstract

The invention discloses a medicine for treating autism and a preparation method of the medicine, and belongs to the technical field of traditional Chinese medicines. The medicine is prepared from the following raw materials: 30 parts of white peony roots, 20 parts of Chinese yam, 20 parts of Chinese dates, 20 parts of coix seeds, 20 parts of haws, 20 parts of Chinese wolfberry, 30 parts of grassleaf sweetflag rhizomes, 10 parts of radix puerariae, 20 parts of chrysanthemums and 1000 parts of pure water. In addition, 200 parts of fructus alpiniae oxyphyllae, 200 parts of snakegourd fruits, 200 parts of oysters, 200 parts of Indian bread with hostwood, 150 parts of raspberry, 100 parts of white sugar and 1000 parts of pure water are added. The medicine is carefully processed by using natural Chinese herbal medicines as the raw materials, and is used for the treatment and the rehabilitation of autism children. The medicine disclosed by the invention is safe and has no side effects.

Description

A kind of medicine for the treatment of infantile autism and preparation method thereof
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Technical field
The invention discloses a kind of medicine for the treatment of infantile autism and preparation method thereof, belong to technical field of Chinese medicines.
Background technology
Infantile autism, is also childhood autism, is a kind of hypotype of pervasive developmental disorders, common with male, and onset is in infantile period, and main manifestations is speech dysplasia, Social disorder in various degree, interest is narrow and way of act is mechanical.About have the patient of 3/4 with obvious mental retardation, part infant has good ability in certain under the background of general mental retardation.
This disease prevalence 3 ~ 4/0,000.But report has the trend increased in recent years, and according to the data of NIH's Mental Health institute (NIMH), U.S.'s autism prevalence is 1 ‰ ~ 2 ‰.Domestic have no autistic the whole nation stream adjusting data, only relevant report has been made in some areas, as 2010 report, Guangdong autism prevalence is 0.67%, and Shenzhen area is up to 1.32%.
Therapeutic Method main at present comprises training interference method and Drug therapy.
Although current autistic interference method is a lot, mostly lack the evidence of evidence-based medicine EBM.There is no optimum treatment scheme, best Therapeutic Method should be the treatment of individuation.Wherein, business initiatives, education and training is the most effective, topmost Therapeutic Method.Target promotes patient's development of speech, improves social contact ability, grasps basic living technical ability and learning skill.
Current Drug therapy there is no method and changes the autistic course of disease, also the specific drug for the treatment of core symptom is lacked, but medicine can improve some emotions and the behavior symptom of patient, as emotional lability, attention deficit and many dynamic, impulsive behavior, aggressive behavior, self inflicted injury and suicide, twitch and obsessive symptoms and psychotic symptoms etc., be conducive to safeguarding patient self or other people safety, implementing education and training and psychotherapy smoothly.Common drug is as follows: central stimulant, is applicable to merge attention deficit and hyperkinetic syndrome shape person.Common drug is methylphenidate.Antipsychotic drug, answers low dose of, short-period used, in use will note drug side effect, particularly EPS.Antidepressant drug, can alleviate repetition stereotyped behavior, obsessive symptoms, improve emotional problem, improves social and communication skill, and for using the dyskinesia that occurs after dopamine receptor antagonist as shunk back, tardive dyskinesia, twitch etc. also have certain effect.
The medicament categories being used for the treatment of now infantile autism is various, has Western medicine, Chinese medicine, biological medicament etc., but curative effect is all not good.A kind of ideal is not also had to be used for the treatment of the medicine of infantile autism at present.
Summary of the invention
Technical problem to be solved by this invention is to provide a kind of medicine for the treatment of infantile autism, and this medicine is the pharmaceutical composition that raw material is prepared from by pure natural plant, the present invention also discloses the preparation method of this pharmaceutical composition.
Medicine of the present invention is prepared as follows:
1) combination A is prepared by following weight portion:
Radix Paeoniae Alba 30-35 part, Rhizoma Dioscoreae 20-30 part, Fructus Jujubae 20-25 part, Semen Coicis 20-25 part, Fructus Crataegi 20-25 part, Fructus Lycii 20-25 part, Rhizoma Acori Graminei 30-35 part, Radix Puerariae 10-15 part, Flos Chrysanthemi 20-25 part, pure water 1000 ~ 2000 parts;
2) combination B is prepared by following weight portion:
Fructus Alpiniae Oxyphyllae 200-250 part, Fructus Trichosanthis 200-250 part, Concha Ostreae 200-250 part, Poria cum Radix Pini 200-250 part, Fructus Rubi 150-200 part, white sugar 100-120 part, pure water 1000 ~ 2000 parts;
3), after combination A and combination B being boiled 1 ~ 2 hour, leach medicinal liquid A and medical liquid B respectively, be chilled to room temperature, remove medicinal residues, and medicinal liquid A and medical liquid B are regulated pH to 8 respectively;
4) isopyknic medicinal liquid A and medical liquid B mixing is got, for subsequent use.
Preferred as one, combination A is by following weight: the Radix Paeoniae Alba 30 parts, Rhizoma Dioscoreae 20 parts, 20 parts, Fructus Jujubae, Semen Coicis 20 parts, Fructus Crataegi 20 parts, Fructus Lycii 20 parts, Rhizoma Acori Graminei 30 parts, Radix Puerariae 10 parts, Flos Chrysanthemi 20 parts, pure water 1000 parts.
Preferred as one, combination B is by following weight: Fructus Alpiniae Oxyphyllae 200 parts, Fructus Trichosanthis 200 parts, Concha Ostreae 200 parts, Poria cum Radix Pini 200 parts, Fructus Rubi 150 parts, white sugar 100 parts, pure water 1000 parts.
The present invention proves through a large amount of clinical practice, for treating the evident in efficacy of infantile autism, and has no side effect, and is the ideal medicament for the treatment of infantile autism.
The remarkable advantage of medicine of the present invention is pure natural plant Chinese herbal medicine, has no side effect, no dependence, good effect.
Detailed description of the invention
Embodiment 1
(1) Radix Paeoniae Alba 30 parts is got, Rhizoma Dioscoreae 20 parts, 20 parts, Fructus Jujubae, Semen Coicis 20 parts, Fructus Crataegi 20 parts, Fructus Lycii 20 parts, Rhizoma Acori Graminei 30 parts, Radix Puerariae 10 parts, Flos Chrysanthemi 20 parts, pure water 1000 parts.
(2) Fructus Alpiniae Oxyphyllae 200 parts is separately added, Fructus Trichosanthis 200 parts, Concha Ostreae 200 parts, Poria cum Radix Pini 200 parts, Fructus Rubi 150 parts, white sugar 100 parts, pure water 1000 parts.
Selected, cleaning, places the above-mentioned Chinese medicine processed respectively in electric heating type shedder, boils respectively, filtering medicinal liquid after 2 hours, removes respectively and abandons the Chinese medicine slag boiled.
(3), after medicinal liquid prepared by the Chinese medicine composition of step (1) and (2) being placed cooling, test its acid-base value with accurate pH test paper respectively, with acetic acid or sodium bicarbonate solution, it is modulated to 8.
(4) by each 500ml of medicinal liquid equivalent for preparing of the Chinese medicine composition of the step (1) of becoming reconciled and (2) import 1000ml simultaneously glass container in stir evenly, for subsequent use.
(5) with the medicinal liquid prepared by glass vial splendid attire step (4), every bottle of 500ml, labeling is for subsequent use.
Embodiment 2
(1) Radix Paeoniae Alba 35 parts is got, Rhizoma Dioscoreae 30 parts, 25 parts, Fructus Jujubae, Semen Coicis 25 parts, Fructus Crataegi 25 parts, Fructus Lycii 25 parts, Rhizoma Acori Graminei 35 parts, Radix Puerariae 15 parts, Flos Chrysanthemi 25 parts, pure water 2000 parts.
(2) Fructus Alpiniae Oxyphyllae 250 parts is separately added, Fructus Trichosanthis 250 parts, Concha Ostreae 250 parts, Poria cum Radix Pini 250 parts, Fructus Rubi 200 parts, white sugar 120 parts, pure water 2000 parts.
Selected, cleaning, the above-mentioned Chinese medicine processed is placed in electric heating type shedder respectively, and the 1000ml that adds water respectively boils, filtering medicinal liquid after 2 hours, removes respectively and abandons the Chinese medicine slag boiled.
(3), after medicinal liquid prepared by the Chinese medicine composition of step (1) and (2) being placed cooling, test its acid-base value with accurate pH test paper respectively, with acetic acid or sodium bicarbonate solution, it is modulated to 8.
(4) by each 500ml of medicinal liquid equivalent for preparing of the Chinese medicine composition of the step (1) of becoming reconciled and (2) import 1000ml simultaneously glass container in stir evenly, for subsequent use.
(5) with the medicinal liquid prepared by glass vial splendid attire step (4), every bottle of 500ml, labeling is for subsequent use.
The using method of the Chinese medicine for the treatment of infantile autism provided by the present invention is as follows: in 6 years old, one day morning and evening of child before the meal respectively once, the course for the treatment of in March one.More than 6 years old morning, noon and afternoon before the meal each once, the course for the treatment of in March one.
Adopt medicine provided by the present invention, applicant place rehabilitation center has seen and treated patients about 500 children.From clinical efficacy, through the treatment of a course for the treatment of, total effective 300 people, effective 182 people, invalid 18 people.Obvious effective rate is 60%, and effective percentage is 36.4%, obtains good clinical effectiveness.(note: invalid finger is taken medicine after a course for the treatment of without any change; Effective finger to be taken medicine after a course for the treatment of in emotion, and behavior and language change; Effective finger in emotion, behavior and language acknowledging has made marked progress after a course for the treatment of of taking medicine, and emotion-directed behavior problem reduces, and language increases, and can set up basic daily communication with father and mother.)
Below the representative instance taking product of the present invention:
Case one, Lee, four years old, people from Qichun, Hubei, from 2 years old, show solitarily unsocial, do not understand instruction, a word was not said, absent minded, does not see people.In April, 2012, when checking treatment at center, center determined to carry out Chinese medicine conditioning to it.Result is that conditioning has just had normal speech in 32 days afterwards, in May 6 center in 2012, and infant embraces suddenly the face parent of mother flatly, really earnestly be a sound mother, the mother of infant said in tears at that time: " I hears that son is my mother finally." at that time the grandparents of child also flowed down exciting tear at the scene.
Case two, Chen, female, 7 years old, people from Shiyan, Hubei.Found that it was hypologia from about 3 years old, murmur to oneself, solitarily peel off, not too listen instruction, mechanical repetition, IQ is on the low side.Autism of children is diagnosed as in healthcare hospital for women & children of Hubei Province.On June 10th, 2011 starts in center rehabilitation medication, and in JIUYUE, 2012 returns to one's perfect health and normally goes to school.Because IQ is on the low side, just upper class hour low academic, child does not usually remember the knowledge of study, and its female requirement continues to take, and IQ raising in 2013, school grade reaches medium level.

Claims (3)

1. treat a medicine for infantile autism, it is characterized in that preparing as follows:
1) combination A is prepared by following weight portion:
Radix Paeoniae Alba 30-35 part, Rhizoma Dioscoreae 20-30 part, Fructus Jujubae 20-25 part, Semen Coicis 20-25 part, Fructus Crataegi 20-25 part, Fructus Lycii 20-25 part, Rhizoma Acori Graminei 30-35 part, Radix Puerariae 10-15 part, Flos Chrysanthemi 20-25 part, pure water 1000 ~ 2000 parts;
2) combination B is prepared by following weight portion:
Fructus Alpiniae Oxyphyllae 200-250 part, Fructus Trichosanthis 200-250 part, Concha Ostreae 200-250 part, Poria cum Radix Pini 200-250 part, Fructus Rubi 150-200 part, white sugar 100-120 part, pure water 1000 ~ 2000 parts;
3), after combination A and combination B being boiled 1 ~ 2 hour, leach medicinal liquid A and medical liquid B respectively, be chilled to room temperature, remove medicinal residues, and medicinal liquid A and medical liquid B are regulated pH to 8 respectively;
4) isopyknic medicinal liquid A and medical liquid B mixing is got, for subsequent use.
2. medicine according to claim 1, is characterized in that, described combination A is by following weight: the Radix Paeoniae Alba 30 parts, Rhizoma Dioscoreae 20 parts, 20 parts, Fructus Jujubae, Semen Coicis 20 parts, Fructus Crataegi 20 parts, Fructus Lycii 20 parts, Rhizoma Acori Graminei 30 parts, Radix Puerariae 10 parts, Flos Chrysanthemi 20 parts, pure water 1000 parts.
3. medicine according to claim 1, is characterized in that, described combination B is by following weight: Fructus Alpiniae Oxyphyllae 200 parts, Fructus Trichosanthis 200 parts, Concha Ostreae 200 parts, Poria cum Radix Pini 200 parts, Fructus Rubi 150 parts, white sugar 100 parts, pure water 1000 parts.
CN201410622090.8A 2014-11-07 2014-11-07 Medicine for treating autism and preparation method thereof Pending CN104306854A (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105148041A (en) * 2015-09-10 2015-12-16 林国良 Rehabilitation-assisted traditional Chinese medicine for pediatric infantile autism
CN105833003A (en) * 2016-05-18 2016-08-10 孙新永 Traditional Chinese medicine composition for treating autism
CN110916192A (en) * 2019-11-25 2020-03-27 垒途智能教科技术研究院江苏有限公司 Probiotic mineral powder capable of preventing and treating autism of children and teenagers and application thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102671053A (en) * 2012-06-11 2012-09-19 原志成 Medicament for treating autism and preparation method thereof
CN103055231A (en) * 2013-01-22 2013-04-24 南宁市神明药物研究所有限责任公司 Method for preparing traditional Chinese medicine preparation

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102671053A (en) * 2012-06-11 2012-09-19 原志成 Medicament for treating autism and preparation method thereof
CN103055231A (en) * 2013-01-22 2013-04-24 南宁市神明药物研究所有限责任公司 Method for preparing traditional Chinese medicine preparation

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105148041A (en) * 2015-09-10 2015-12-16 林国良 Rehabilitation-assisted traditional Chinese medicine for pediatric infantile autism
CN105833003A (en) * 2016-05-18 2016-08-10 孙新永 Traditional Chinese medicine composition for treating autism
CN110916192A (en) * 2019-11-25 2020-03-27 垒途智能教科技术研究院江苏有限公司 Probiotic mineral powder capable of preventing and treating autism of children and teenagers and application thereof
CN110916192B (en) * 2019-11-25 2021-04-13 垒途智能教科技术研究院江苏有限公司 Probiotic mineral powder capable of preventing and treating autism of children and teenagers and application thereof
WO2021102910A1 (en) * 2019-11-25 2021-06-03 垒途智能教科技术研究院江苏有限公司 Probiotic mineral powder capable of preventing and treating infantile autism of children and adolescents, and application thereof

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