CN104306688A - Traditional Chinese medicine composition for treating tinnitus - Google Patents
Traditional Chinese medicine composition for treating tinnitus Download PDFInfo
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/232—Angelica
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- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
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- A61K36/88—Liliopsida (monocotyledons)
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Abstract
The invention belongs to the technical field of traditional Chinese medicine, and particularly relates to a traditional Chinese medicine composition for treating tinnitus. The traditional Chinese medicine composition is prepared by adopting the following raw material medicines in parts by weight: 10-20 parts of rhizoma atractylodis macrocephalae, 3-9 parts of liquorice, 25-35 parts of astragalus membranaceus, 10-20 parts of radix ophiopogonis, 10-20 parts of codonopsis pilosula, 10-20 parts of radix glehniae, 25-35 parts of the root of red-rooted salvia, 9-15 parts of angelica sinensis, 9-15 parts of polygala tenuifolia, 25-35 parts of spina date seeds, 25-35 parts of tuber fleeceflower stem, 10-20 parts of poria cocos and 25-35 parts of dens draconis. Although the traditional Chinese medicine composition is a conventional medicine in medicine selection, the conventional medicine is combined reasonably and the dosage is considered rationally via the accurate dialectic analysis of the disease, the traditional Chinese medicine composition can obtain a satisfactory treatment effect.
Description
Technical field
The invention belongs to technical field of Chinese medicines, specifically refer to a kind of Chinese medicine composition for the treatment of tinnitus.
Background technology
Tinnitus refers to the conscious in ear ring of patient, and surrounding there is no corresponding sound source, is a kind of subjective feeling.In crowd, tinnitus incidence rate estimates at 10-20%, and accounts for 5% because tinnitus is seriously sought medical advice, and over-65s has more than 10% to have tinnitus main suit, and the incidence rate of person hard of hearing tinnitus is higher.At present in the treatment of tinnitus, the therapeutic effect performance of doctor trained in Western medicine is poor, and Traditional Chinese Medicine shows original therapeutic effect in the treatment of tinnitus one disease.
Summary of the invention
The object of the invention is in the traditional Chinese medical science on the understanding basis of tinnitus one disease and then provide a kind of Chinese medicine composition for the treatment of this disease.
For realizing above-mentioned technical purpose, the technical solution used in the present invention is: a kind of Chinese medicine composition for the treatment of tinnitus, it is characterized in that, this Chinese medicine composition adopts the material medicine of following weight proportion to combine: Rhizoma Atractylodis Macrocephalae 10-20 part, Radix Glycyrrhizae 3-9 part, Radix Astragali 25-35 part, Radix Ophiopogonis 10-20 part, Radix Codonopsis 10-20 part, Radix Glehniae 10-20 part, Radix Salviae Miltiorrhizae 25-35 part, Radix Angelicae Sinensis 9-15 part, Radix Polygalae 9-15 part, Semen Ziziphi Spinosae 25-35 part, Caulis Polygoni Multiflori 25-35 part, Poria 10-20 part, Dens Draconis 25-35 part.
Further, in above-mentioned Chinese medicine composition, optimum weight part of each material medicine is: the Rhizoma Atractylodis Macrocephalae 15 parts, 6 parts, Radix Glycyrrhizae, the Radix Astragali 30 parts, Radix Ophiopogonis 15 parts, Radix Codonopsis 15 parts, Radix Glehniae 15 parts, Radix Salviae Miltiorrhizae 30 parts, Radix Angelicae Sinensis 12 parts, Radix Polygalae 12 parts, Semen Ziziphi Spinosae 30 parts, Caulis Polygoni Multiflori 30 parts, 15 parts, Poria, Dens Draconis 30 parts.
The instructions of taking of this Chinese medicine composition is: after being mixed in grams by the material medicine of above-mentioned weight proportion, conveniently the method for fried Chinese medicine gets its medicine juice 300-500ml, and every day one is secondary, and a point morning and evening drinks for twice.
Prescription analysis: " Ling Shu Miraculous Pivot or Divine Axis. a pathogen cacosplanchnia shape section " middle record " heart faint and hesitant pulse is tinnitus "; Record in ancient and Modern Medicine " sorrow is pondered over, then sad, and the heart considers blood consumption must cause Hiccough and deaf "; Record in " medical science main story " " flaming up of heart-fire, its people must Hiccough and deaf "; " Ling Shu Miraculous Pivot or Divine Axis. sea opinion " " deficiency of marrow-reservoir, then vertigo and tinnitus ".As can be seen here, tinnitus one disease duty at the heart, lid ear is clear Sora no ana, the institute of clear positive intersection, and heart arteries and veins loses supports or flaming up of heart-fire all can cause the heresy of wind heat fire stagnation, blocks auditory meatus and sends out as tinnitus.Accordingly in Chinese medicine composition provided by the present invention, get Dens Draconis, Semen Ziziphi Spinosae, Radix Angelicae Sinensis, Radix Salviae Miltiorrhizae, Radix Polygalae, Caulis Polygoni Multiflori nourish blood to calm the nerves, get Radix Ophiopogonis, Radix Glehniae lung moistening clears away heart-fire to fall heart-fire.See again tinnitus one disease and be mainly in older people, therefore tinnitus one disease must be lost and associate, therefore in this Chinese medicine composition, get the Radix Astragali, Radix Codonopsis QI invigorating with the deficit of gas, middle scorched earth, gets the Rhizoma Atractylodis Macrocephalae, Poria, Radix Glycyrrhizae to hold up middle Jiao.Said medicine is share, QI invigorating, strong in, nourish heart, pathogenic fire reducing to be to reach the effect for the treatment of tinnitus.Although this Chinese medicine composition is common drug on choice of drug, by disease dialectical Analyses accurately, conventional medicine is carried out reasonable compatibility, consideration consumption, it can obtain gratifying therapeutic effect.
Detailed description of the invention
Below in conjunction with embodiment, Chinese medicine composition provided by the present invention is described further.
Embodiment 1
A kind of Chinese medicine composition for the treatment of tinnitus, it is characterized in that, this Chinese medicine composition adopts the material medicine of following weight proportion to combine: Rhizoma Atractylodis Macrocephalae 20g, Radix Glycyrrhizae 9g, Radix Astragali 35g, Radix Ophiopogonis 20g, Radix Codonopsis 20g, Radix Glehniae 20g, Radix Salviae Miltiorrhizae 35g, Radix Angelicae Sinensis 15g, Radix Polygalae 15g, Semen Ziziphi Spinosae 35g, Caulis Polygoni Multiflori 35g, Poria 20g, Dens Draconis 35g.
Toxicity test: in the present embodiment, for carrying out toxicity test to medicine, the weight portion of each material medicine is got its maximum weight part and is tested, in acute toxicity testing research, first the median lethal dose(LD 50) (LD50) of this Chinese medicine composition is determined, but fail to measure its LD50, illustrate that this Chinese medicine composition acute toxicity is less.And then measure its maximum dosage-feeding: medicine is made into the Cmax that mice can accept, with maximum volume gastric infusion, one day 2 times, observes 30 days.Dosage is pressed per weight and is calculated, and reach 60 times of people's dosage, death or other abnormal phenomenas do not appear in all mices, illustrate that its safety is very high.
Embodiment 2
A kind of Chinese medicine composition for the treatment of tinnitus, it is characterized in that, this Chinese medicine composition adopts the material medicine of following weight proportion to combine: Rhizoma Atractylodis Macrocephalae 15g, Radix Glycyrrhizae 6g, Radix Astragali 30g, Radix Ophiopogonis 15g, Radix Codonopsis 15g, Radix Glehniae 15g, Radix Salviae Miltiorrhizae 30g, Radix Angelicae Sinensis 12g, Radix Polygalae 12g, Semen Ziziphi Spinosae 30g, Caulis Polygoni Multiflori 30g, Poria 15g, Dens Draconis 30g.
Clinical trial:
Since 2013, accepted tinnitus patient 84 example for medical treatment, to get rid of caused by obvious ear physiological disorder tinnitus patient 18 example, residue 64 routine patients, the age from 38-79 year, 51.2 years old mean age.Diagnostic criteria is the property sent out during patient oneself reflection or regular tinnitus, and during talk, part is with amblyacousia symptom.Treatment standard is determined mainly for remission degree, general medication is no more than two weeks, tinnitus persistent period, attack times minimizing or audition make moderate progress as effective, the conscious tinnitus of patient disappears for being cured, effective and healing sum proportion is total effective rate, and the medication state of an illness on the three continues to increase the weight of, and patient is difficult to adhere to, or medication one week symptom is without alleviation, check without improvement sign or PD person to be invalid.Treatment situation is as following table:
| Number of cases | Cure | Effective | Invalid | Cure rate % | Total effective rate % |
| 64 | 45 | 12 | 7 | 70.31 | 89.06 |
Be limited to condition, direct contrast is not done in clinical experiment, but therewith the first two year the similar patient treatment situation of accepting for medical treatment compare, the therapeutic effect of this medicine strengthens significantly, particularly this drug treatment cycle mostly was for 2-3 weeks, and shorten about 50% on year-on-year basis, expenses for medicine cost reduces by more than 60%.Cure and follow up a case by regular visits to for latter 1 year, the patient of more than 80% has no recurrence, and not yet finds other diseases of causing because of medication, and thus this medicine creates desirable influence at sample plot.
Model case
Female, 53 years old, tinnitus history 2 years, period took multiple Drug therapy, had part to improve symptom, but to recur very soon, reaction time medical, and its tinnitus is in persistent state, had deaf tendency, had a restless night, vexed, the heart is vexed, the left cun soft and thready pulse of pulse-taking, heavy.The Chinese medicine composition that taking provides in this embodiment reacts tinnitus symptom after 1 week obviously improves, discontinuity tinnitus is improved to by persisting tinnitus, the religion of sleeping at night time obviously extends before taking medicine, patient's confidence increases, and continues to take this Chinese medicine composition 2 weeks, and tinnitus disappears, auditory rehabilitation is normal, sleep simultaneously improves, light and spacious in the heart, without unhappy sense.Apart from modern 1 year, tinnitus symptom was again without recurrence.
Embodiment 3
A kind of Chinese medicine composition for the treatment of tinnitus, it is characterized in that, this Chinese medicine composition adopts the material medicine of following weight proportion to combine: the Rhizoma Atractylodis Macrocephalae 10 parts, 9 parts, Radix Glycyrrhizae, the Radix Astragali 25 parts, Radix Ophiopogonis 20 parts, Radix Codonopsis 10 parts, Radix Glehniae 20 parts, Radix Salviae Miltiorrhizae 25 parts, Radix Angelicae Sinensis 15 parts, Radix Polygalae 9 parts, Semen Ziziphi Spinosae 35 parts, Caulis Polygoni Multiflori 25 parts, 20 parts, Poria, Dens Draconis 25 parts.
Embodiment 4
A kind of Chinese medicine composition for the treatment of tinnitus, it is characterized in that, this Chinese medicine composition adopts the material medicine of following weight proportion to combine: the Rhizoma Atractylodis Macrocephalae 20 parts, 3 parts, Radix Glycyrrhizae, the Radix Astragali 35 parts, Radix Ophiopogonis 10 parts, Radix Codonopsis 20 parts, Radix Glehniae 10 parts, Radix Salviae Miltiorrhizae 35 parts, Radix Angelicae Sinensis 9 parts, Radix Polygalae 15 parts, Semen Ziziphi Spinosae 25 parts, Caulis Polygoni Multiflori 35 parts, 10 parts, Poria, Dens Draconis 35 parts.
Claims (2)
1. treat the Chinese medicine composition of tinnitus for one kind, it is characterized in that, this Chinese medicine composition adopts the material medicine of following weight proportion to combine: Rhizoma Atractylodis Macrocephalae 10-20 part, Radix Glycyrrhizae 3-9 part, Radix Astragali 25-35 part, Radix Ophiopogonis 10-20 part, Radix Codonopsis 10-20 part, Radix Glehniae 10-20 part, Radix Salviae Miltiorrhizae 25-35 part, Radix Angelicae Sinensis 9-15 part, Radix Polygalae 9-15 part, Semen Ziziphi Spinosae 25-35 part, Caulis Polygoni Multiflori 25-35 part, Poria 10-20 part, Dens Draconis 25-35 part.
2. a kind of Chinese medicine composition for the treatment of tinnitus according to claim 1, it is characterized in that, in described Chinese medicine composition, optimum weight part of each material medicine is: the Rhizoma Atractylodis Macrocephalae 15 parts, 6 parts, Radix Glycyrrhizae, the Radix Astragali 30 parts, Radix Ophiopogonis 15 parts, Radix Codonopsis 15 parts, Radix Glehniae 15 parts, Radix Salviae Miltiorrhizae 30 parts, Radix Angelicae Sinensis 12 parts, Radix Polygalae 12 parts, Semen Ziziphi Spinosae 30 parts, Caulis Polygoni Multiflori 30 parts, 15 parts, Poria, Dens Draconis 30 parts.
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| CN201410587422.3A CN104306688A (en) | 2014-10-29 | 2014-10-29 | Traditional Chinese medicine composition for treating tinnitus |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105267630A (en) * | 2015-05-10 | 2016-01-27 | 孙喜范 | Traditional Chinese medicine for treating tinnitus |
| CN106474315A (en) * | 2016-10-20 | 2017-03-08 | 王凯茜 | A kind of Chinese medicine for treating tinnitus |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1172662A (en) * | 1997-08-15 | 1998-02-11 | 张清 | Powder for treating tinnitus |
| CN102836347A (en) * | 2012-09-18 | 2012-12-26 | 孙丽 | Traditional Chinese medicine for treating tinnitus |
-
2014
- 2014-10-29 CN CN201410587422.3A patent/CN104306688A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1172662A (en) * | 1997-08-15 | 1998-02-11 | 张清 | Powder for treating tinnitus |
| CN102836347A (en) * | 2012-09-18 | 2012-12-26 | 孙丽 | Traditional Chinese medicine for treating tinnitus |
Non-Patent Citations (1)
| Title |
|---|
| 李啟良等: "《中西医结合法治疗高海拔地区神经性耳鸣的临床疗效观察》", 《吉林医学》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105267630A (en) * | 2015-05-10 | 2016-01-27 | 孙喜范 | Traditional Chinese medicine for treating tinnitus |
| CN106474315A (en) * | 2016-10-20 | 2017-03-08 | 王凯茜 | A kind of Chinese medicine for treating tinnitus |
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Application publication date: 20150128 |