CN104306651A - Tibetan medicine composition with whitening and freckle removing function and application and preparation method of Tibetan medicine composition - Google Patents
Tibetan medicine composition with whitening and freckle removing function and application and preparation method of Tibetan medicine composition Download PDFInfo
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- CN104306651A CN104306651A CN201410625095.6A CN201410625095A CN104306651A CN 104306651 A CN104306651 A CN 104306651A CN 201410625095 A CN201410625095 A CN 201410625095A CN 104306651 A CN104306651 A CN 104306651A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/51—Gentianaceae (Gentian family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/10—General cosmetic use
Abstract
The invention discloses a Tibetan medicine composition with whitening and freckle removing functions and application and a preparation method of the Tibetan medicine composition. Aiming at the defects that in the prior art a whitening and freckle removing product which takes Tibetan medicine materials as raw materials is high in price, the invention provides the Tibetan medicine composition with the whitening and freckle removing functions. The Tibetan medicine composition comprises the following raw material components: 2-4 parts of chishuluodi, 1-3 parts of iris ensata thumb, 1-3 parts of western Sichuan synotis wallichii, 1-3 parts of Chinese parsley fruit and 1-3 parts of swertia multicaulis. The composition is a Tibetan medicine composition which is prepared from components in appreciate ratio. The chemical analysis experiment and the human body testing show that the Tibetan medicine composition has the whitening and freckle removing functions. The Tibetan medicine composition can be used for preparing whitening and freckle removing products, and can be used for preparing whitening and freckle removing medicines and/or healthcare products. The invention further provides a preparation method of the Tibetan medicine composition.
Description
Technical field
The present invention relates to a kind of compositions, particularly relate to a kind of Tibetan medicinal composition with whitening effect and uses thereof, preparation method.
Background technology
Along with the change of natural environment, and living habit changes and the increase of operating pressure, cause human endocrine to get muddled, Metabolic disorder, mistake makes the impact of factors such as applying some make up in addition, human body face is caused to occur various mottle, such as freckle, chloasma, cyasma and senile plaque etc.Its essence all belongs to cutaneous pigmentation.Cutaneous pigmentation is the pigment change that human body skin causes skin for various reasons and presents different colours, different range and the different depth.Show as cutaneous pigmentation and form black patch, brown patch, isabelline patch, cyan patch etc. at facial area on skin, even.Cutaneous pigmentation causes the skin metabolism obstacle dermatopathy occurred extremely due to multiple internal and external factor impact, and its producing cause and pathogenesis are very complicated.Whether traditional medicine thinks that gas is defended in nutrient blood that the fitness of skin depends primarily on flesh table unimpeded, if depression of liver-QI, functional activity of QI being not smooth, liver lose sensible, spleen fortune weary it, can not biochemical nutrient blood with nourishing the liver, disturbance of QI-blood and face, therefore pigmentation.Pigmentation belongs in the traditional medicine category such as " chloasma ", " dusty face ".
Existing whitening and speckle dispelling product is a lot of in the market, but is that raw material carries out formula mainly with chemical composition, and some product is even containing some hormonal components.Although this series products in a short time result of use is obvious, once stop using, often occur that skin color becomes more black, pigment intensification etc.Natural plants action temperature and, untoward reaction is little, and safety is high, has broad application prospects.Nearby, the health-care effect of traditional Tibetan medicine and pharmacology is valued by the people.The whitening and speckle dispelling product being raw material with Tibetan medicine material is mainly effectiveness composition with Stigma Croci, utilizes croceous effect of invigorating blood circulation, makes skin health ruddy, and namely so-called in medical book " clothes grow lower unit for a long time, improving healthy complexion.But real Stigma Croci is expensive, usually need deeply processing to extract its active component, therefore products obtained therefrom is usually expensive.
Summary of the invention
Object of the present invention is just to provide a kind ofly possesses Tibetan medicinal composition of whitening and speckle dispelling effect and preparation method thereof.
For achieving the above object, technical scheme of the present invention is as follows:
Possess a Tibetan medicinal composition for whitening and speckle dispelling effect, it is characterized in that: raw material components is the slow ripe trailing plants base of a fruit 2 ~ 4 parts, Chinese small iris 1 ~ 3 part, the western combined-ear chrysanthemum in river 1 ~ 3 part, Fructus Coriandri sativi 1 ~ 3 part, many stems Herba Swertiae bimaculatae 1 ~ 3 part.
In above-mentioned composition, each component is:
The slow ripe trailing plants base of a fruit, Tibetan language name " pricks Ah sound of crying or vomiting ".It is the herb of the hollow hemp nettle (Lloydia serotina) of the hollow hemp nettle platymiscium of Liliaceae.According to the record of the Tibetan medicine allusion quotation collection such as the Four-Volume Medical Code, " the maternal grass of degree ", in traditional Tibetan medicine and pharmacology, effect of the slow ripe trailing plants base of a fruit is mainly clearing away heat to improve acuity of vision, yellow river water, more wound, synthetism folding, for traumatic injury, various oculopathy etc.
Chinese small iris, another name Ma Lian, calabash shell serving as a dipper are real, Flos Iridis Chinensis, are flower, seed and the root of Iridaceae Jris plant Chinese small iris (Iris lactea).Enter explosive component difference, the flower of Chinese small iris, seed and root have clearing away heat and cooling blood, inducing diuresis to remove edema, cooling blood for hemostasis, clearing away heat-damp and promoting diuresis, effect of heat-clearing and toxic substances removing respectively.Chinese small iris mainly act on heat-clearing and toxic substances removing, inducing diuresis for treating stranguria syndrome, promoting blood circulation and detumescence, main sore throat, stranguria with turbid discharge, arthralgia, cellulitis malignant boil, incised wound.
The western combined-ear chrysanthemum in river (Synotis solidaginea), another name river western tail medicine chrysanthemum is Compositae combined-ear chrysanthemum platymiscium.Primary efficacy is that heat-clearing and toxic substances removing controls skin ulcer, synthetism, and all heat of liver heat removing gallbladder etc., cure mainly wound inflammation, swelling, the diseases such as acute conjunctivitis, dermatitis, furuncle, traumatic injury.
Fructus Coriandri sativi is the dry mature fruit of samphire coriander (Coriandrum sativum L.), standard number WS3-BC-0043-95.Primary efficacy is heat clearing away, induces sweat, stomach invigorating, sick for " Baconic's wood cloth ", dyspepsia, inappetence, thirsty etc.
Many stems Herba Swertiae bimaculatae is Gentianaceae Swertia plant.Tibetan medicine Swertia (Swertia L.) plant, is commonly called as " ZANGYINCHEN ", is one of valuable eight delicacies Tibetan medicine that Tibetan history is long.Record according to the Four-Volume Medical Code, Tibetan medicine Herba Swertiae bimaculatae, all herbal medicine, cold in nature, bitter in the mouth, has effect of heat-clearing and toxic substances removing, liver heat removing function of gallbladder promoting, cures mainly the diseases such as icterohepatitis, liver cirrhosis, hepatic ascites.Present medical science confirm its have protect the liver, antiinflammatory, antiviral, protection nervus centralis, protection digestive tract, blood sugar lowering effect.Many stems Herba Swertiae bimaculatae (Swertia multicaulis) is the one in Tibetan medicine Herba Swertiae bimaculatae, Tibetan language name " Sai Baogu vertebra key ".Record according to the Tibetan medicine and pharmacology ancient books such as " degree maternal grass ", " Jingzhubencao ", this product bitter in the mouth, pungent, puckery, bitter in the mouth after digestion, cool in nature.Have heat clearing away, removing toxic substances, connects arteries and veins, hemostasis, granulation promoting function, for pestilence, and jaundice, stomachache, intestinal acute diseases such as cholera and sunstroke epidemic disease etc.
Under optimum condition, the said goods can be optimized: first each Raw material processing can be prepared into water extract by above-mentioned Tibetan medicinal composition, again by each water extract according to the slow ripe trailing plants base of a fruit 2 ~ 4 parts, Chinese small iris 1 ~ 3 part, the western combined-ear chrysanthemum in river 1 ~ 3 part, Fructus Coriandri sativi 1 ~ 3 part, many stems Herba Swertiae bimaculatae 1 ~ 3 part of ratio mix homogeneously, obtained.
In above-mentioned Tibetan medicinal composition, water extract preparation method is: get raw material, clean, dry, adds raw material weight 8 times ~ 12 times water gagings, soaks 0.5 hour, decoct 1.5 hours, and 300 eye mesh screens filter, and collects filtrate; Medicinal residues add raw material weight 6 times ~ 10 times water gagings again, decoct 1.5 hours, and 300 eye mesh screens filter, and collect filtrate; Merge twice filtrate, be condensed into thick paste (till provoking filamentation, moisture about 50%), obtain each former material water extract.
The present composition is with above-mentioned 5 kinds of traditional medicines for raw material, according to the Tibetan medicinal composition of suitable proportion composition of prescription first.Through chemical analysis test and normal individual trial display, the present composition has whitening and speckle dispelling effect.
Based on above-mentioned drug effect principle, Tibetan medicinal composition of the present invention can be applied to preparation whitening, speckle dispelling series products, can be applied to preparation whitening, medicine for removing speckle and/or health promoting product.Medicine and/or health promoting product comprise " the accurate word of medicine " product and/or " adornment font size " product etc.
The whitening being effectiveness composition with above-mentioned Tibetan medicinal composition, medicine for removing speckle and/or health promoting product.Specifically with above-mentioned Tibetan medicinal composition for active component, be equipped with acceptable adjuvant on pharmaceutics, corresponding pharmaceutical preparation can be prepared into.With regard to conventional medicament pharmacy principle, product of the present invention can be prepared into all dosage forms of medicine for external use.
The present invention also provides the preparation method of above-mentioned Tibetan medicinal composition, and its technical scheme is as follows:
The preparation method of above-mentioned Tibetan medicinal composition, is characterized in that: get raw material, clean, dry, adds raw material weight 8 ~ 12 times of water, soaks 0.5 hour, decoct 1.5 hours, and 300 eye mesh screens filter, and collects filtrate; Medicinal residues add raw material weight 6 ~ 10 times of water gagings, decoct 1.5 hours, and 300 eye mesh screens filter, and collect filtrate; Merge twice filtrate, be condensed into thick paste, obtain each component water extract; Get each raw water extract, to scale deal mix homogeneously and get final product.
Compared with prior art, the invention has the beneficial effects as follows: (1) provides a kind of new Tibetan medicinal composition, each component of said composition can work in coordination with enhancement skin microcirculation, and restraint of tyrosinase is active, eliminate pigmentation, there is elimination, improve the object of the mottle such as freckle, chloasma.(2) Tibetan medicinal composition of the present invention proves to have drug safety through human trial.(3) each component of Tibetan medicinal composition of the present invention is all disclosed in all kinds of medical material (thing) standard, is commonly easy to get.(4) the easy easy control of Tibetan medicinal composition formulation preparation method of the present invention.(5) Tibetan medicinal composition of the present invention can be applied to preparation whitening, speckle dispelling series products, can be applied to preparation whitening, medicine for removing speckle and/or health promoting product.(6) preparation method of Tibetan medicinal composition of the present invention is provided.
Detailed description of the invention
Below in conjunction with preferred embodiment, technical solution of the present invention is further described.
Embodiment one
Prepare Tibetan medicinal composition of the present invention.
1, get the raw materials ready
Choose the first-class slow ripe trailing plants base of a fruit of quality, Chinese small iris, the western combined-ear chrysanthemum in river, Fructus Coriandri sativi, many stems Herba Swertiae bimaculatae, clean, dry, stand-by.
2, raw materials water extract
Take arbitrary raw material respectively appropriate, add former section weight 8 times ~ 12 times water, soak 0.5 hour, decoct 1.5 hours, 300 eye mesh screens filter, and collect filtrate; Medicinal residues add former section weight 6 times ~ 10 times water gagings again, decoct 1.5 hours, and 300 eye mesh screens filter, and collect filtrate; Merge twice filtrate, be condensed into thick paste (till provoking filamentation, moisture about 50%), obtain this medical material water extract.Prepare the slow ripe trailing plants base of a fruit respectively according to the method, Chinese small iris, the western combined-ear chrysanthemum in river, Fructus Coriandri sativi, many stems Herba Swertiae bimaculatae extract are stand-by.
3, Tibetan medicinal composition preparation
Get each raw water extract, namely deal (table 1) mix homogeneously obtains Tibetan medicinal composition to scale.
Table 1 each component extract proportioning (/mg)
| ? | The slow ripe trailing plants base of a fruit | Chinese small iris | The western combined-ear chrysanthemum in river | Fructus Coriandri sativi | Many stems Herba Swertiae bimaculatae |
| 1 | 30 | 10 | 10 | 10 | 10 |
| 2 | 40 | 10 | 10 | 10 | 10 |
| 3 | 30 | 20 | 20 | 20 | 20 |
Embodiment two
Preparation is with the whitening and freckle-removing liquid of Tibetan medicinal composition of the present invention for effectiveness composition.
Preparation matrix solution (weight ratio): water 84.39%, glycerol 5.83%, butanediol 3.50%, propylene glycol 3.50%, betanin 0.58%, hydroxypropyl emthylcellulose 0.35%, pantothenylol 0.23%, sodium salicylate 0.12%, methyl hydroxybenzoate 0.06%, EDETATE SODIUM 0.06%, sorbitol ester-201.17%, essence 0.23%, mix homogeneously.
Get each extract and matrix solution, namely mix homogeneously obtains whitening and freckle-removing liquid to scale.Whitening and freckle-removing liquid component ratio (weight ratio) is: slow ripe trailing plants base of a fruit extract 3.86%, horse lotus extract 2.58%, the western combined-ear chrysanthemum extract 2.58% in river, Fructus Coriandri sativi extract 2.58%, many stems Herba Swertiae bimaculatae extract 2.58%, substrate 85.82%.
Test example one
The tyrosinase inhibition rate of testing example one gained Tibetan medicinal composition.
Sample preparation: Example one 3 groups prepares gained Tibetan medicinal composition 10mg respectively, and adding distil water is diluted to 1mg/ml, stand-by.
Measure light absorption value A1, A2, A3, A0, standard operation is: accurately absorption above-mentioned sample 1ml, pH6.8 phosphate buffer 1 ml and 2% tyrosinase solution 1ml and Folin reagent start reaction, whole reaction continues 20min in the constant temperature of 37 DEG C, measures each sample absorbance after reaction terminates in 680nm place.By following formulae discovery tyrosinase inhibition rate.
Tyrosinase inhibition rate (%)=[(A1-A0)-(A2-A3)]/(A1-A0) × 100%
In formula: the absorbance that the blank product of A0-do not add tryrosinase and sample in standard operation are surveyed; A1-in standard operation, an interpolation tryrosinase does not add the absorbance that sample mix liquid is surveyed; The absorbance that A2-simultaneously add in standard operation tryrosinase and sample mix liquid are surveyed; A3-add in standard operation sample does not add the absorbance that tryrosinase mixed liquor is surveyed.
Table 2 each Tibetan medicinal composition sample tyrosinase inhibition rate
| Embodiment one is divided into groups | 1 | 2 | 3 |
| Tyrosinase inhibition rate (%) | 42.6 | 38.3 | 48.3 |
Tyrosinase inhibition rate test result shows, Tibetan medicinal composition sample has obvious inhibitory action to tryrosinase.
Test example two
Embodiment two gained whitening and freckle-removing liquid, carries out human clinical trial.
Test method: choose the volunteer 200 that facial speckle dispelling, chloasma, the colour of skin are obscure in cycle county, Qinghai, 20 ~ 50 years old age, wherein male 95, women 105.Volunteer is divided into test group and matched group two groups at random, often organizes 100.
Test group: after clean of every day, before sleeping, whitening and freckle-removing liquid of the present invention is spread on face 15min ~ 20min, with warm water cleaning, does not smear other skin care item.One month experimental period.
Certain brand whitening and freckle-removing liquid cosmetics commercially available are spread on face 15min ~ 20min before sleeping, with warm water cleaning, do not smear other skin care item by matched group: after clean of every day.One month experimental period.
Evaluation criterion: experienced by patient's readme, and computer comparison skin texture figure identifies colour of skin whitening degree and mottle desalination degree.Effective: the colour of skin highlights, mottle color dodge.Invalid: not to be any change before the colour of skin and mottle and test.
Result of the test: effective 85 examples of test group, effective percentage 85%; Effective 68 examples of matched group, effective percentage 68%.An example is not had to occur the phenomenon such as skin allergy, discomfort in test group.Conclusion: whitening cosmetics of the present invention has obvious whitening and speckle dispelling effect.
Claims (10)
1. possess a Tibetan medicinal composition for whitening and speckle dispelling effect, it is characterized in that: raw material components is the slow ripe trailing plants base of a fruit 2 ~ 4 parts, Chinese small iris 1 ~ 3 part, the western combined-ear chrysanthemum in river 1 ~ 3 part, Fructus Coriandri sativi 1 ~ 3 part, many stems Herba Swertiae bimaculatae 1 ~ 3 part.
2. Tibetan medicinal composition according to claim 1, is characterized in that: described raw material components is the slow ripe trailing plants base of a fruit 3 parts, Chinese small iris 1 ~ 2 part, the western combined-ear chrysanthemum in river 1 ~ 2 part, Fructus Coriandri sativi 1 ~ 2 part, many stems Herba Swertiae bimaculatae 1 ~ 2 part.
3. Tibetan medicinal composition according to claim 1, is characterized in that: described raw material components is slow ripe trailing plants base of a fruit water extract 2 ~ 4 parts, Chinese small iris water extract 1 ~ 3 part, the western combined-ear chrysanthemum water extract in river 1 ~ 3 part, Fructus Coriandri sativi water extract 1 ~ 3 part, many stems Herba Swertiae bimaculatae water extract 1 ~ 3 part.
4. Tibetan medicinal composition according to claim 3, is characterized in that: described raw material components is slow ripe trailing plants base of a fruit water extract 3 parts, Chinese small iris water extract 1 ~ 2 part, the western combined-ear chrysanthemum water extract in river 1 ~ 2 part, Fructus Coriandri sativi water extract 1 ~ 2 part, many stems Herba Swertiae bimaculatae water extract 1 ~ 2 part.
5. Tibetan medicinal composition according to claim 3, is characterized in that: described raw material components is one of following three kinds of schemes:
Scheme one: slow ripe trailing plants base of a fruit water extract 30 parts, Chinese small iris water extract 10 parts, the western combined-ear chrysanthemum water extract in river 10 parts, Fructus Coriandri sativi water extract 10 parts, many stems Herba Swertiae bimaculatae water extract 10 parts;
Scheme two: slow ripe trailing plants base of a fruit water extract 40 parts, Chinese small iris water extract 10 parts, the western combined-ear chrysanthemum water extract in river 10 parts, Fructus Coriandri sativi water extract 10 parts, many stems Herba Swertiae bimaculatae water extract 10 parts;
Scheme three: slow ripe trailing plants base of a fruit water extract 30 parts, Chinese small iris water extract 20 parts, the western combined-ear chrysanthemum water extract in river 20 parts, Fructus Coriandri sativi water extract 20 parts, many stems Herba Swertiae bimaculatae water extract 20 parts.
6. according to the arbitrary described Tibetan medicinal composition of claim 3 ~ 5, it is characterized in that: water extract preparation method is: get raw material, clean, dry, add raw material weight 8 ~ 12 times of water, soak 0.5 hour, decoct 1.5 hours, 300 eye mesh screens filter, and collect filtrate; Medicinal residues add raw material weight 6 ~ 10 times of water gagings, decoct 1.5 hours, and 300 eye mesh screens filter, and collect filtrate; Merge twice filtrate, be condensed into thick paste, obtain each component water extract.
7. the preparation method of the arbitrary described Tibetan medicinal composition of Claims 1 to 5, is characterized in that: get raw material, clean, dry, and add raw material weight 8 ~ 12 times of water, soak 0.5 hour, decoct 1.5 hours, 300 eye mesh screens filter, and collect filtrate; Medicinal residues add raw material weight 6 ~ 10 times of water gagings, decoct 1.5 hours, and 300 eye mesh screens filter, and collect filtrate; Merge twice filtrate, be condensed into thick paste, obtain each component water extract; Get each raw water extract, to scale deal mix homogeneously and get final product.
8. the application of the arbitrary described Tibetan medicinal composition of Claims 1 to 5 in preparation whitening, speckle dispelling series products.
9. with the whitening that is effectiveness composition of the arbitrary described Tibetan medicinal composition of Claims 1 to 5, medicine for removing speckle and/or health promoting product.
10., with the external use liquid product that Tibetan medicinal composition according to claim 6 is effectiveness composition, it is characterized in that:
Comprise effectiveness composition 14.18% by weight and matrix solution 85.82%;
Described effectiveness composition comprises slow ripe trailing plants base of a fruit extract 3.86%, horse lotus extract 2.58%, the western combined-ear chrysanthemum extract 2.58% in river, Fructus Coriandri sativi extract 2.58%, many stems Herba Swertiae bimaculatae extract 2.58% by weight;
Described matrix solution comprises water 84.39%, glycerol 5.83%, butanediol 3.50%, propylene glycol 3.50%, betanin 0.58%, hydroxypropyl emthylcellulose 0.35%, pantothenylol 0.23%, sodium salicylate 0.12%, methyl hydroxybenzoate 0.06%, EDETATE SODIUM 0.06%, sorbitol ester-201.17%, essence 0.23% by weight.
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Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105963187A (en) * | 2016-06-14 | 2016-09-28 | 中山大学惠州研究院 | Application of synotis auriculata in preparation of sun-screening agent |
| CN107789495A (en) * | 2017-11-17 | 2018-03-13 | 黄礼莲 | A kind of nti-freckle water desalinated chloasma faciei and improve color spot regeneration and preparation method thereof |
| CN107789496A (en) * | 2017-11-17 | 2018-03-13 | 黄礼莲 | A kind of nti-freckle water for being effectively improved chloasma faciei and preparation method thereof |
| CN107802741A (en) * | 2017-11-17 | 2018-03-16 | 黄礼莲 | A kind of nti-freckle water for significantly improving color spot regeneration and preparation method thereof |
| CN107875286A (en) * | 2017-11-17 | 2018-04-06 | 黄礼莲 | A kind of nti-freckle water of significantly desalination chloasma faciei and preparation method thereof |
| CN107929180A (en) * | 2017-11-17 | 2018-04-20 | 黄礼莲 | A kind of nti-freckle water for facial colour spot and preparation method thereof |
| CN109966216A (en) * | 2017-12-28 | 2019-07-05 | 伽蓝（集团）股份有限公司 | A kind of Chinese small iris extract and its new opplication |
| CN110882346A (en) * | 2019-12-31 | 2020-03-17 | 西洛次仁 | Tibetan medicine medicament and preparation method thereof |
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