CN104305206A - Enteral nutrition preparation for fat-burning intervention on metabolic syndrome and application thereof - Google Patents

Enteral nutrition preparation for fat-burning intervention on metabolic syndrome and application thereof Download PDF

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CN104305206A
CN104305206A CN201410634933.6A CN201410634933A CN104305206A CN 104305206 A CN104305206 A CN 104305206A CN 201410634933 A CN201410634933 A CN 201410634933A CN 104305206 A CN104305206 A CN 104305206A
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fat
metabolic syndrome
preparation
buckwheat
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寿吉祥
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GUANGZHOU WEALTHCOME HEALTH PRODUCT Co Ltd
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GUANGZHOU WEALTHCOME HEALTH PRODUCT Co Ltd
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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/30—Foods or foodstuffs containing additives; Preparation or treatment thereof containing carbohydrate syrups; containing sugars; containing sugar alcohols, e.g. xylitol; containing starch hydrolysates, e.g. dextrin
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/175—Amino acids
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nutrition Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Mycology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Botany (AREA)
  • Molecular Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

The invention relates to an enteral nutrition preparation for fat-burning intervention on metabolic syndrome and an application thereof. The preparation is prepared through mixing corns, Chinese yams, buckwheat, soy protein, whey protein, linseed oil, lipoic acid, L-carnitine, minerals, vitamins and other raw materials. The preparation is a special formula for the nutritional intervention on metabolic syndrome of the very low-calorie dietetic therapy, has the effects of promoting steatolysis, promoting weight loss, reducing blood pressure, blood glucose and blood fat, improving the insulin sensitivity and the liver function, and reducing the lean body mass loss, and achieves good prevention and supportive therapeutic efficacies for metabolic syndrome. The preparation can be used for the development of healthcare products and food aimed at promoting weight loss, and has broad application prospects.

Description

A kind of enteral nutrition preparation and application thereof of firing fat and intervening metabolic syndrome
Technical field
The present invention relates to food and field of health care products, especially relate to a kind of enteral nutrition preparation and the application thereof of firing fat and intervening metabolic syndrome.
Background technology
Metabolic syndrome (Metabolism Syndrome, MetS) be the pathological state of multiple Metabolite abnormal aggregation, a complex set of metabolic disorder disease group, it is the high risk factor causing diabetes (DM) cardiovascular and cerebrovascular disease (CVD), insulin resistance (IR) is the common pathophysiological basis that metabolic syndrome occurs, research finds, can the generation of effectively prevention of metabolic syndrome diabetes mellitus and angiocardiopathy by the intervention of earlier life mode.
Insulin resistance (Insulin Resistance, IR) be the central pathological physiology course of metabolic syndrome, cause stomach fat to be assembled, inflammatory reaction, the major reason of the rising of blood sugar, blood pressure and blood fat disorder, research finds, improves IR all from the abnormal metabolism alleviating MetS in various degree, can be conducive to the generation preventing diabetes and cardiovascular and cerebrovascular disease by different modes.
At present, lose weight to have by keeping on a diet and improve insulin sensitivity, reduce blood pressure, reduce blood sugar, improve sugar tolerance, reduce inflammation the effects such as reaction, effectively can prevent the generation of diabetes and angiocardiopathy.Clinical research finds, under not improving dietary structure situation, pure reduces energy intake, in Body weight loss process, as thin soma can not be kept, reduce fat content, easily occur that wasting, fat content increase, aggravation insulin resistance, is unfavorable for the treatment of metabolic syndrome.
For this reason, develop a kind of enteral nutrition preparation that effectively can alleviate insulin resistance and improve metabolic syndrome, be mainly used in dietary restriction treatment, play the effect of active treatment metabolic syndrome, the prevention for diabetes and cardiovascular and cerebrovascular disease has positive effect.
Summary of the invention
For effectively improving the validity of dietetic treatment, reduce the discomforts such as hard to bear, the weak and thin body loss of the hunger easily occurred in dietary restriction therapeutic process simultaneously, according in dietary restriction process, for ensureing that essential nutrients is taken in, prevent resistance to decline, a series of discomforts such as thin body loss and hunger, we research and develop a special nutritional formula for dietary restriction treatment metabolic syndrome.
The first, ensure the absorption of good protein.
Protein mainly selects lactalbumin and soybean protein, and research finds, lactalbumin belongs to good protein, has raising immunity, repairs damaged tissues and supplementary amino acid needed by human body, has promotion Body weight loss simultaneously, improve the content effect of thin soma.And large quantity research finds, soybean protein has stimulates lipolysis effect, wherein containing isoflavones, has effects such as improving blood fat, blood sugar and anti-osteoporosis.In addition, study discovery further, the absorption of red meat protein has promotion body weight increasing action, has simultaneously and promotes inflammatory reaction, promotion tumour and increase cardiovascular risk factors effect.Research proves, in dietary restriction process, ensure that the absorption of proteins necessary is conducive to maintaining basal metabolic rate, reduce thin body and lose, epidemic prevention power declines and increases the effects such as satiety.
The second, preferred low glycemic carbohydrate.
Low Glycemic Index Foods is conducive to stabilizing blood sugar, there is the effect reducing appetite, containing a large amount of resistant starch in the buckwheat chosen and corn, large quantity research finds, resistant starch is conducive to delaying that blood sugar raises, reduces energy intake, loses weight, Constipation and improve the effects such as blood fat.In addition, also containing enriching oligomeric polysaccharide in buckwheat, being conducive to increasing satiety, alleviating hunger thus reducing energy intake.
Chinese yam, has another name called Chinese yam, is the dry rhizome of Dioscoreaceae plant Chinese yam Dioscorea opposita Thunb., property sweet, taste put down, return spleen, lung, kidney channel, there is tonifying spleen nourishing the stomach, the functions such as beneficial lung, the puckery essence of kidney tonifying of promoting the production of body fluid, it contains a large amount of resistant starch, glutinous albumen and dietary fiber, has and improves digestive function, delayed absorption, alleviate lipidosis, have losing weight, reduce the effect of blood sugar and blood fat, and Shennong's Herbal is classified as top grade, take clear-headed and clear-sighted for a long time, make light of one's life by commiting suicide not hungry, promote longevity.
3rd, reduce fat intake, improve unrighted acid and take in.
Large quantity research all confirms, the absorption of significant quantities of fat and higher unsaturated fatty acid is the key factor causing body weight increase and insulin resistance, the absorption reducing fat is the necessary condition improving metabolic syndrome, in addition, improve the absorption of unrighted acid, be conducive to reducing cholesterolemia, triglycerides and level of inflammation, be conducive to reducing cardiovascular risk factors.In addition, research finds, linseed oil is rich in the unrighted acid such as alpha-linolenic acid and omega-fatty acid, has to reduce blood fat, improve insulin sensitivity and the curative effect such as to lose weight, and has potent cardiovascular and cerebrovascular protective effect.
4th, strengthening minerals and vitamins adds
When dietary restriction is treated, easily there are the microelement deficiencies such as B family vitamin, calcium, magnesium and zinc in human body, on this basis, according to China resident Nutrition intake guidelines, the trace elements such as B family vitamin, calcium, magnesium and zinc are added in strengthening, lack performance to reduce the nutrients such as alopecia, weak and immunity degradation.
5th, add combustion fat nutrient
Large quantity research confirms, l-cn has promotion fatty acid oxidation, improve basal metabolic rate, promote waste discharge in fat oxidation process, alpha-lipoic acid has promotion lipolysis, anti-oxidant, reduce appetite and increase the effects such as basal metabolic rate, above-mentioned two kinds of nutrients all have auxiliary losing weight, and improve insulin sensitivity, reduce the effect such as blood sugar and blood fat.
In sum, for occurring that nutrient lacks in prevention dietary restriction process, this formula adds needed by human nutrient, preferred edible Chinese medicine " Chinese yam " simultaneously, tonifying speen and tonifying kidney, combustion fat nutrient l-cn and alpha-lipoic acid is coordinated to promote Body weight loss, this formula has increase satiety, improve basal metabolic rate, promote Body weight loss, reduce thin body to lose, what may occur in prevention dietary restriction is weak, the performances such as resistance decline and alopecia, have and improve insulin resistance, improve blood sugar, the cardiovascular risk factors such as blood fat and blood pressure, effective treatment Metabolic Syndrome Patients Central obesity.
The present invention is prepared from by the bulk drug calculating following weight parts by mass percentage:
Maltodextrin 10 ~ 15%, corn flour 5 ~ 15%, buckwheat 5 ~ 15%, yam flour 5 ~ 15%, soyabean protein powder 25 ~ 35%, PURE WHEY 10% ~ 25%, linseed oil 5 ~ 10%, mineral mixture 1.5 ~ 2.0%, vitamin mixtures 0.2 ~ 0.5%, l-cn 0.5-1.5%, alpha-lipoic acid 0.5-1.5%
The weight of above-mentioned raw materials medicine is preferred:
Maltodextrin 15%, corn flour 5%, buckwheat 15%, yam flour 5%, soyabean protein powder 35%, PURE WHEY 15%, linseed oil 6%, mineral mixture 1.7%, vitamin mixtures 0.5%, l-cn 1.0%, alpha-lipoic acid 0.8%.
The weight of above-mentioned raw materials medicine is also preferred:
Maltodextrin 10%, corn flour 15%, buckwheat 5%, yam flour 10%, soyabean protein powder 30%, PURE WHEY 20%, linseed oil 7%, mineral mixture 1.0%, vitamin mixtures 0.5%, l-cn 1.5%, alpha-lipoic acid 0.5%.
The weight of above-mentioned raw materials medicine is also preferred:
Maltodextrin 12%, corn flour 10%, buckwheat 5%, yam flour 13%, soyabean protein powder 25%, PURE WHEY 25%, linseed oil 5.5%, mineral mixture 1.7%, vitamin mixtures 0.3%, l-cn 1.2%, alpha-lipoic acid 1.3%.
The weight of above-mentioned raw materials medicine is also preferred:
Maltodextrin 10%, corn flour 10%, buckwheat 5.5%, yam flour 10%, soyabean protein powder 28%, PURE WHEY 22%, linseed oil 10%, mineral mixture 1.6%, vitamin mixtures 0.4%, l-cn 1.0%, alpha-lipoic acid 1.5%.
The weight of above-mentioned raw materials medicine is also preferred:
Maltodextrin 10%, corn flour 5%, buckwheat 10%, yam flour 12%, soyabean protein powder 30%, PURE WHEY 20%, linseed oil 8.5%, mineral mixture 1.8%, vitamin mixtures 0.5%, l-cn 0.7%, alpha-lipoic acid 1.5%.
The weight of above-mentioned raw materials medicine is also preferred:
Maltodextrin 13%, corn flour 6%, buckwheat 10%, yam flour 12%, soyabean protein powder 32%, PURE WHEY 18%, linseed oil 5%, mineral mixture 2.0%, vitamin mixtures 0.3%, l-cn 0.7%, alpha-lipoic acid 1.0%.
Accompanying drawing explanation
Accompanying drawing is a kind of enteral nutrition preparation preparation method flow chart firing fat and intervene metabolic syndrome.
Detailed description of the invention
Below in conjunction with accompanying drawing, the present invention is illustrated further.
As shown in the figure, pulvis preparation method of the present invention is maltodextrin, mineral mixture, vitamin mixtures, the pre-mixing of first time two dimension; Add with l-cn, lipoic acid again, the pre-mixing of row second time two dimension; Then corn flour, buckwheat, yam flour, soyabean protein powder, PURE WHEY, the capable efficient three-dimensional hybrid of linseed oil is added.Sieve, packing, obtain preparation of the present invention.
Experimental example: the clinical trial data of medical food of the present invention
The curative effect of firing fat intervene the enteral nutrition preparation of metabolic syndrome for checking the present invention is a kind of, we recruit 30 routine Metabolic Syndrome Patients, and 30 routine patients all complete clinical research.
(1) inclusive criteria: age 18-60 year; Possess following three or whole persons: 1. fat: BMI>=30.0kg/m 2, male sex waistline>=90cm, women>=80cm; 2. blood fat disorder: triglycerides>=1.7mmol/L and (or) HDL-C < 1.03mmol/L (man) or < 1.29mmol/L (female); 3. hypertension: blood pressure>=130/85mmHg, and (or) Definite Hypertension curer; 4. hyperglycaemia: fasting blood-glucose>=5.6mmol/L, and (or) make a definite diagnosis diabetes and curer.
(2) exclusion standard: gestation, lactation or menstrual period women; The heart, Liver and kidney function are abnormal; Malignant tumour and inpatient with haematological diseases; Active tuberculosis patient; The ulcers of serious gastrorrhagia; Diabetes; Take and affect glucose-lipid metabolism medicine person; Can not partner treatment, compliance difference person; Do not sign Informed Consent Form.
(3) embodiment
This programme enters group 30 example altogether and suffers from experimenter, and all experimenters all sign Informed Consent Form, and diet restriction therapy is divided into 4 stages.The first phase (Phase I): very low calorie diet phase in January, take in heat about 700kcal/d altogether every day, comprise 4-5 meal combustion fat nutrition powder (often eat 20-30g) and vegetable juice low in calories; The second phase (Phase II): low caloric diet phase in January, take in heat about 850Kcal altogether every day, comprise 3 meal combustion fat nutrient powder (often eat 20-30g) and 1 protein diet (fish poultry); The third phase (Phase III): low caloric diet phase in February, take in heat 1100Kcal every day, comprise 2 meal combustion fat nutrient powder (often eat 20-30g), 2 protein diets (fish, breast, egg, fowl etc.), low calorie fruit and each 1 part of vegetables; The fourth phase (Phase IV): balanced diet phase low in calories in February, take in heat 1250Kcal every day, coarse food grain (thickness collocation 1: 1 principle), low calorie fruit, vegetables, 2 parts of protein diets (fish, fowl, breast, egg, beans), 1 meal combustion fat nutrient powder (often eat 30g), vegetable oil, prohibits animal oil, pluck and red meat etc.Period keeps daily exercise amount, does not carry out strong physical sport, can carry out taking a walk, climb the mountain, swim and the motion such as by bike, taboo basketball, football, hurries up and the strong physical sport such as long-distance running, within 2 weeks, follows up a case by regular visits to 1 time.
(4) observation index
Ordinary circumstance: body weight, blood pressure, heart rate, waistline, fat content
Subjective index: monthly periodic monitoring hungry, weak, headache, stomachache, feel sick, constipation, the bad reaction situation such as chilly.
Blood testing: before treatment, intervenes February, measures liver zymetology, blood sugar, four items of blood lipid tests, blood uric acid, insulin level and hs-CRP (Hs-CRP) and free fatty (Free fatty acid, FFA) after treatment.The equal bio-chemical detector of whole blood index measures.
(4) statistical procedures and the summarization of data
After clinical testing terminates, all clinical data SPSS software carries out statistical analysis.Clinical total effects, clinical symptoms etc. after treatment are carried out statistical analysis, compared, the curative effect of last objective evaluation EA of the present invention and security thereof.
Statistical method: grouped data X 2inspection, ranked data two samples compare Wilcoxon rank test (correction), two sample averages compare with t inspection or Wilcoxon rank test, compare with paired t-test or Wilcoxon pairing rank test before and after self, all statistical checks all adopt two-sided test, and P value is less than or equal to 0.05 has statistical significance by being considered to checked difference.
(5) result
1, ordinary circumstance
Total experimenter 60 example of this research, through statistical analysis, mean age is 38 ± 15.3 (y), male/female ratio is 8/22, as shown in table 1, intervene through Phase I, weight decline 6.1 ± 2.0kg (P < 0.001), body mass index decline 2.1 ± 0.6kg/m 2(P < 0.001), waistline decline 8.0 ± 2.0cm (P < 0.001), systolic pressure decline 9.2 ± 3.4mmHg (P < 0.001), diastolic pressure decline 7.2 ± 2.1mmHg (P < 0.001); During Phase II, weight continues decline 3.1 ± 1.7kg (P < 0.001), body mass index decline 1.1 ± 0.6kg/m 2(P < 0.001), waistline reduces 4.3 ± 1.9cm (P < 0.001), and systolic pressure and diastolic pressure have no remarkable decline.
In the Phase III phase, endosome Quality Down 3.6 ± 0.8kg in February (P=0.003), body mass index decline 1.3 ± 0.5 (P=0.002), waistline reduces 4.9 ± 1.2cm (P < 0.001), systolic pressure decline 8.2 ± 4.4mmHg (P=0.004), diastolic pressure has no remarkable decline; In the Phase IV phase, endosome Quality Down 2.0 ± 0.7kg in February (P=0.006), body mass index decline 0.7 ± 0.3 (P=0.005), waistline reduces 2.0 ± 1.2cm (P=0.003), and systolic pressure and diastolic pressure are showed no remarkable decline.Through dietary therapy half a year, all patient body Quality Downs are obvious, and waistline, systolic pressure and diastolic pressure all significantly decline, and result for the treatment of is obvious.
Table 1: diet restriction therapy is on the impact of body weight, waistline and blood pressure
2, the change of cardiovascular risk factors
As shown in table 2, after Phase I intervenes, blood sugar, blood fat, uric acid, insulin, C peptide and HOMA-IR etc. all present conspicuousness and decline, and meanwhile, in body, Inflammatory parameter hs-CRP significantly improves; In the dietary therapy stage subsequently, Metabolic Syndrome Patients cardiovascular risk factors continues to decline, and shows that this therapeutic scheme tool is significantly improved insulin resistance, reduces the effect of Metabolic Syndrome Patients cardiovascular risk factors.
3, the change of liver zymetology
As shown in table 2, after diet restriction therapy is intervened, patients serum's glutamic-pyruvic transaminase, glutamic-oxalacetic transaminease and γ-paddy amine acyl transpeptidase level all presents remarkable decline, point out this nutritional meal replacement to have and improve the effect of Metabolic Syndrome Patients inflammation, point out this nutritional preparation to have clear improvement fat metabolism, promote the curative effect such as fat splitting and the fat caused NASH for the treatment of.
Table 2: diet restriction therapy is on the impact of biochemical indicator
5, fat content
As shown in table 3, after diet restriction therapy is intervened, experimenter's fat content presents Progressive symmetric erythrokeratodermia and declines, during Phase IV, weight declines and reduces, and fat content continues to decline, point out this therapy effectively can reduce body fat content, improve thin soma ratio, the thin body in loss of weight process effectively can be prevented to lose, be conducive to improving health states.
Table 3: body composition change list
6, bad reaction
As shown in table 4, treatments period, during Phase I, there is the discomforts such as the weak and insomnia of halitosis, hunger, constipation, stomachache, headache in some patients; After intervening February, in the Phase II phase, above-mentioned bad reaction declines gradually, and 90 days time, the discomforts such as hunger, stomachache are comparatively obvious; Some patients allergic reaction (allergic rhinitis, nettle rash etc.) increases the weight of in February before the treatment, and in therapeutic process subsequently, allergic symptom significantly alleviates; 180 days time, except stomachache and hunger, bad reaction all disappears.This therapy has no obvious adverse reaction at present, and mainly based on the inanition discomfort of intestines and stomach, incidence is low, and tolerance is good.
Table 4: the bad reaction generation number of cases of diet restriction therapy
6, therapeutic evaluation
Clinical research shows, this dietetic treatment has and significantly reduces body weight, reduces blood pressure, the cardiovascular risk factors such as blood sugar, blood fat, promote lipolysis, improve insulin resistance, alleviate waistline, alleviate inflammation, reduce inflammatory reaction, tolerance is good, without obvious adverse reaction, can effectively reduce Metabolic Syndrome Patients cardiovascular risk factors, contribute to the generation reducing Metabolic Syndrome Patients cardiocerebrovasculaevents events, there is applications well prospect.
6, discuss
The present invention is formed by specific fat-reducing nutrient formulated, adds edible Chinese medicine " Chinese yam " simultaneously and plays the fat effect that disappears of making light of one's life by commiting suicide, on reasonable diet architecture basics, this nutritional meal replacement of proportioning, there is reduction weight, reduce thin body and lose, reduce fat content, reduce blood pressure, improve blood sugar, blood fat, insulin sensitivity and liver function, significantly reduce Metabolic Syndrome Patients cardiovascular risk factors, tolerance is good, without obvious adverse reaction, be conducive to clinical application.
Embodiment 1
Maltodextrin 15, mineral mixture 1.7, vitamin mixtures 0.5, the pre-mixing of first time two dimension; Add l-cn 1, lipoic acid 0.8, the pre-mixing of row second time two dimension; Then add corn flour 5, buckwheat 15, yam flour 5, soyabean protein powder 35, PURE WHEY 15, the efficient three-dimensional hybrid of linseed oil 6 row.Sieve, packing, obtain pulvis of the present invention.
Embodiment 2
Maltodextrin 10, mineral mixture 1, vitamin mixtures 0.5, the pre-mixing of first time two dimension; Add l-cn 1.5, lipoic acid 0.5, the pre-mixing of row second time two dimension; Then add corn flour 15, buckwheat 5, yam flour 10, soyabean protein powder 30, PURE WHEY 20, the efficient three-dimensional hybrid of linseed oil 7 row.Sieve, packing, obtain pulvis of the present invention.
Embodiment 3
Maltodextrin 12, mineral mixture 1.7, vitamin mixtures 0.3, the pre-mixing of first time two dimension; Add l-cn 1.2, lipoic acid 1.3, the pre-mixing of row second time two dimension; Then add corn flour 10, buckwheat 5, yam flour 13, soyabean protein powder 25, PURE WHEY 25, the efficient three-dimensional hybrid of linseed oil 6 row.Sieve, packing, obtain pulvis of the present invention.
Embodiment 4
Maltodextrin 10, mineral mixture 1., vitamin mixtures 0.4, the pre-mixing of first time two dimension; Add l-cn 1, lipoic acid 1.5, the pre-mixing of row second time two dimension; Then add corn flour 10, buckwheat 5.5, yam flour 10, soyabean protein powder 28, PURE WHEY 22, the efficient three-dimensional hybrid of linseed oil 10 row.Sieve, packing, obtain pulvis of the present invention.
Embodiment 5
Maltodextrin 10, mineral mixture 1.8, vitamin mixtures 0.5, the pre-mixing of first time two dimension; Add l-cn 0.7, lipoic acid 1.5, the pre-mixing of row second time two dimension; Then add corn flour 5, buckwheat 10, yam flour 12, soyabean protein powder 30, PURE WHEY 20, the efficient three-dimensional hybrid of linseed oil 8.5 row.Sieve, packing, obtain pulvis of the present invention.
Embodiment 6
Maltodextrin 13, mineral mixture 2.0, vitamin mixtures 0.3, the pre-mixing of first time two dimension; Add l-cn 0.7, lipoic acid 1, the pre-mixing of row second time two dimension; Then add corn flour 6, buckwheat 10, yam flour 12, soyabean protein powder 32, PURE WHEY 18, the efficient three-dimensional hybrid of linseed oil 5 row.Sieve, packing, obtain pulvis of the present invention.

Claims (8)

1. fire enteral nutrition preparation and an application thereof that fat intervenes metabolic syndrome, it is characterized in that it is prepared from by the bulk drug calculating following weight parts by mass percentage:
Maltodextrin 10 ~ 15%, corn flour 5 ~ 15%, buckwheat 5 ~ 15%, yam flour 5 ~ 15%, soyabean protein powder 25 ~ 35%, PURE WHEY 10% ~ 25%, linseed oil 5 ~ 10%, mineral mixture 1.5 ~ 2.0%, vitamin mixtures 0.2 ~ 0.5%, l-cn 0.5-1.5%, alpha-lipoic acid 0.5-1.5%.
2. a kind of enteral nutrition preparation and application thereof of firing fat and intervening metabolic syndrome according to claim 1, it is characterized in that, the weight portion of following raw material medicaments is:
Maltodextrin 15%, corn flour 5%, buckwheat 15%, yam flour 5%, soyabean protein powder 35%, PURE WHEY 15%, linseed oil 6%, mineral mixture 1.7%, vitamin mixtures 0.5%, l-cn 1.0%, alpha-lipoic acid 0.8%.
3. a kind of enteral nutrition preparation and application thereof of firing fat and intervening metabolic syndrome according to claim 1, it is characterized in that, the weight portion of following raw material medicaments is:
Maltodextrin 10%, corn flour 15%, buckwheat 5%, yam flour 10%, soyabean protein powder 30%, PURE WHEY 20%, linseed oil 7%, mineral mixture 1.0%, vitamin mixtures 0.5%, l-cn 1.5%, alpha-lipoic acid 0.5%.
4. a kind of enteral nutrition preparation and application thereof of firing fat and intervening metabolic syndrome according to claim 1, it is characterized in that, the weight portion of following raw material medicaments is:
Maltodextrin 12%, corn flour 10%, buckwheat 5%, yam flour 13%, soyabean protein powder 25%, PURE WHEY 25%, linseed oil 5.5%, mineral mixture 1.7%, vitamin mixtures 0.3%, l-cn 1.2%, alpha-lipoic acid 1.3%.
5. a kind of enteral nutrition preparation and application thereof of firing fat and intervening metabolic syndrome according to claim 1, it is characterized in that, the weight portion of following raw material medicaments is:
Maltodextrin 10%, corn flour 10%, buckwheat 5.5%, yam flour 10%, soyabean protein powder 28%, PURE WHEY 22%, linseed oil 10%, mineral mixture 1.6%, vitamin mixtures 0.4%, l-cn 1.0%, alpha-lipoic acid 1.5%.
6. a kind of combustion fat enteral nutrition preparation and application thereof intervening metabolic syndrome according to claim 1, it is characterized in that, the weight portion of following raw material medicaments is:
Maltodextrin 10%, corn flour 5%, buckwheat 10%, yam flour 12%, soyabean protein powder 30%, PURE WHEY 20%, linseed oil 8.5%, mineral mixture 1.8%, vitamin mixtures 0.5%, l-cn 0.7%, alpha-lipoic acid 1.5%.
7. a kind of combustion fat enteral nutrition preparation and application thereof intervening metabolic syndrome according to claim 1, it is characterized in that, the weight portion of following raw material medicaments is:
Maltodextrin 13%, corn flour 6%, buckwheat 10%, yam flour 12%, soyabean protein powder 32%, PURE WHEY 18%, linseed oil 5%, mineral mixture 2.0%, vitamin mixtures 0.3%, l-cn 0.7%, alpha-lipoic acid 1.0%.
8. a kind of combustion fat enteral nutrition preparation and the application thereof intervening metabolic syndrome according to any one of claim 1-7, is characterized in that: said preparation is powder.
CN201410634933.6A 2014-11-12 2014-11-12 Enteral nutrition preparation for fat-burning intervention on metabolic syndrome and application thereof Withdrawn CN104305206A (en)

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CN105747235A (en) * 2016-03-04 2016-07-13 通泰心脑健康管理有限公司 Diet composition able to improve symptoms of metabolic syndrome
CN107872958A (en) * 2015-05-06 2018-04-03 南加利福尼亚大学 Meals are imitated and strengthened in the fasting for treating hypertension and lipid disorders
CN108618126A (en) * 2018-04-10 2018-10-09 陕西三正医用营养有限公司 A kind of Chinese medicine compound prescription weight-reducing special diet food and preparation method thereof
CN109007840A (en) * 2018-09-18 2018-12-18 广东雪芝康生物科技有限公司 A kind of nutritive plant powder and preparation method thereof by adjusting gene reducing weight and blood fat
CN110169580A (en) * 2019-06-26 2019-08-27 重庆康泉健康管理有限公司 Adjust metabolism, blood glucose, blood pressure, the comprehensive nutrition powder of blood lipid and preparation method thereof
CN110558568A (en) * 2019-10-25 2019-12-13 陕西中鸿科瑞再生医学研究院有限公司 functional food for reducing high blood pressure, high blood sugar and preparation method thereof
US10631564B2 (en) 2015-06-19 2020-04-28 University Of Southern California Enterically coated microparticle compositions and methods for modified nutrient delivery
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CN107872958A (en) * 2015-05-06 2018-04-03 南加利福尼亚大学 Meals are imitated and strengthened in the fasting for treating hypertension and lipid disorders
EP3291693A4 (en) * 2015-05-06 2019-04-03 University of Southern California Fasting mimicking and enhancing diet for treating hypertension and lipid disorders
RU2724525C2 (en) * 2015-05-06 2020-06-23 Юниверсити Оф Саутерн Калифорния Method of treating high levels of insulin or glucose using a hypocaloric or calorie-free diet or diet simulating abstinence from food
US11000057B2 (en) 2015-05-06 2021-05-11 University Of Southern California Fasting mimicking and enhancing diet for treating hypertension and lipid disorders
US10631564B2 (en) 2015-06-19 2020-04-28 University Of Southern California Enterically coated microparticle compositions and methods for modified nutrient delivery
US10744070B2 (en) 2015-06-19 2020-08-18 University Of Southern California Enteral fast access tract platform system
CN105747235A (en) * 2016-03-04 2016-07-13 通泰心脑健康管理有限公司 Diet composition able to improve symptoms of metabolic syndrome
CN108618126A (en) * 2018-04-10 2018-10-09 陕西三正医用营养有限公司 A kind of Chinese medicine compound prescription weight-reducing special diet food and preparation method thereof
CN109007840A (en) * 2018-09-18 2018-12-18 广东雪芝康生物科技有限公司 A kind of nutritive plant powder and preparation method thereof by adjusting gene reducing weight and blood fat
CN110169580A (en) * 2019-06-26 2019-08-27 重庆康泉健康管理有限公司 Adjust metabolism, blood glucose, blood pressure, the comprehensive nutrition powder of blood lipid and preparation method thereof
CN110558568A (en) * 2019-10-25 2019-12-13 陕西中鸿科瑞再生医学研究院有限公司 functional food for reducing high blood pressure, high blood sugar and preparation method thereof

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