CN104288636A - Pharmaceutical composition and application thereof - Google Patents

Pharmaceutical composition and application thereof Download PDF

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CN104288636A
CN104288636A CN201410569035.7A CN201410569035A CN104288636A CN 104288636 A CN104288636 A CN 104288636A CN 201410569035 A CN201410569035 A CN 201410569035A CN 104288636 A CN104288636 A CN 104288636A
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herba
radix
parts
caulis
pharmaceutical composition
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CN104288636B (en
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王小英
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Beijing Miao Xitang Medical Research Institute Co ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8969—Polygonatum (Solomon's seal)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/11—Pteridophyta or Filicophyta (ferns)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/26—Aristolochiaceae (Birthwort family), e.g. heartleaf
    • A61K36/268—Asarum (wild ginger)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/36—Caryophyllaceae (Pink family), e.g. babysbreath or soapwort
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/45—Ericaceae or Vacciniaceae (Heath or Blueberry family), e.g. blueberry, cranberry or bilberry
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/74—Rubiaceae (Madder family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/90—Smilacaceae (Catbrier family), e.g. greenbrier or sarsaparilla
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/904—Stemonaceae (Stemona family), e.g. croomia

Abstract

The invention discloses a pharmaceutical composition prepared by soaking the following crude drugs in parts by weight: 125-250 parts of polygonatum cyrtonema, 125-250 parts of asarum wulingense, 125-250 parts of asiatic toddalia roots, 120-220 parts of stemona tuberosa lour, 120-250 parts of hedyotis uncinella, 120-220 parts of akebia trifoliate, 125-250 parts of alangium chinense, 130-210 parts of gaultheria yunnanensis, 125-250 parts of rhizoma smilacis glabrae, 120-230 parts of dysphania ambrosioides, 120-230 parts of pyrrosia lingua, 120-230 parts of sargentgloryvine stems, 125-250 parts of dipsacus asper, 125-250 parts of ficus carica and 125-250 parts of lycopodii herbs. The pharmaceutical composition is prepared by soaking a plurality of wild crude drugs according to a certain ratio, can achieve the effect of treating an internal illness by external treatment after being externally used and particularly has a favorable effect on treating myasthenia caused by neuralgic amyotrophy.

Description

Medical composition and its use
Technical field
The present invention relates to technical field of traditional Chinese medicine, especially a kind of pharmaceutical composition, particularly relate to this pharmaceutical composition and the application in treatment neuron amyotrophy myasthenia thereof.
Background technology
Miao ethnic group is distributed more widely, and great majority are with river, Yunnan-Guizhou and Southeast Asia European Region, and it is lived in has in advantageous pure natural oxygen bar natural environment.The peaks rises one above the other in the distance, and rivers in length and breadth, have a moderate climate, and rainfall is abundant, and blue montains and green waters natural vegetation is in great numbers, and planting, move, mineral drug resource is very abundant, is always China's medical material major production areas.The fraternal procreation of living in these areas of various nationalities for thousands of years, body-building ploughing and weeding, and in the long history combated the disease, create abundant clinical medicine theory knowledge hierarchy, become the important component part of China's traditional medicine.Due to the past Miao ethnic group without word, the kind of medicine used, title and medicinal experience etc. only pass by the oral account heart, brain note etc.Some medicines or loose be loaded in Chinese transcript and ancient book on Chinese herbal medicine, therefore the special book monograph of Seedling medicine is few.After 1949, by living in concentrated communities Miao ethnic group, regional medicine is investigated widely, housekeeping, and Miao ethnic group's medicine starts to be loaded into the whole nation or endemic monograph.As: " China National medicine will " first volume (1984) record Miao Ethnomedicine 40 kinds; Volume Two (nineteen ninety) records Miao Ethnomedicine 30 kinds; " Miao ethnic group's medicine collection " (1988) record Miao Ethnomedicine 163 kinds; " Guizhou minority nationality medicine collection " (1989) record Miao Ethnomedicine 91 kinds; Miao Ethnomedicine 340 kinds is recorded in " Miao Minority " (1992).Guizhou Science Press (2010.11) first edition, first time publishes, conventional plant amedica 289 kinds.Many Miao Ethnomedicine are all included in other relevant books also having the provinces and regions such as Hunan, Yunnan, Guangxi to publish and the scientific paper delivered.According to incompletely statistics, medicine common at present can reach 1800 kinds more than, conventional about kind more than 300.
The mountain area drug resource that Miao ethnic group lives in concentrated communities is of a great variety, output is big, quality good, be Plain, China East China and the North China Plain many area institute can not and.As the medical material Poria of: Guizhou main exit, Rhizoma Gastrodiae, Radix Platycodonis, the Rhizoma Pinelliae, Rhizoma Arisaematis, the Radix Polygoni Multiflori, Rhizoma Polygonati, Ramulus Uncariae Cum Uncis, the Cortex Eucommiae, Ganoderma, Radix Codonopsis, large Radix seu Caulis Schisandrae Sinensis, Pseudobulbus Bletillae (Rhizoma Bletillae), Rhizoma amorphophalli, Herba Houttuyniae, Radix Sophorae Flavescentis, Rhizoma Coptidis etc., the autonomous prefecture that many main products are lived in concentrated communities in several Miao ethnic group and autonomous county.Only Poria is in the autonomous county of Miao ethnic group of several Gelao in Southeast Guizhou Miao-Dong Autonomous Prefecture and famous Qian Bei Drug Storage area under one's jurisdiction, Zun Yi, and annual production just reaches 10692.9 quintals; Cortex Phellodendri annual production reaches 8706 kilograms, and Fructus Evodiae reaches 42.8 quintals, and Radix Platycodonis annual production reaches 191384 kilograms.Only Rhizoma Gastrodiae, Yilao-Mao Autonomous County of Wuchuan true at Guizhou Province Bei Dao and Bouyei-Miao Autonomous Prefecture of Qiannan, annual production just reaches 30,000 ten thousand kilograms.Wild Ganoderma reaches more than 10000 kilogram, and famous noble three large precious " gastrodia tuber eucommia Ganoderma lucidum seu Japonicum ", the medical material that other output are large is also a lot.From various places, numerous medicine city grand occasion among the people also can fully show the rich of Miao Ethnomedicine resource, and some medicine municipalization size stands are tens of to hundreds of, all kinds of wild (minority man kind) fresh, dry medical material tens to hundreds of kind of going on the market.Modal medical material as: various Caulis seu Radix Schisandrae Henryi, Radix Chimonanthi praecocis, hundred gold bars, Radix Alangii, Radix seu Herba Gei aleppici, constellation, Herba Bulbophylli Odoratissim, Heiguteng exract, Radix Toddaliae Asiaticae, Radix Aconiti Kusnezoffii, Herba Anemones vitifoliae, eight pawl gold, Herba Epimedii, Spora Lygodii, Caulis et folium gaultheriae yunnanensis, Pseudobulbus Bletillae (Rhizoma Bletillae), Fructus Rosae Laevigatae, Radix Cynanchi Paniculati, Herba Agrimoniae, Herba Hyperici Japonici etc.The rare kind of part is separately had to have sale as also even in Radix et Rhizoma Dysosmatis, JIUYUE life, Radix Psammosilenes, Herba Ophioglossi, purslane speedwell Herba, Squama Manis, gentle grass, Radix Codonopsis, Rhizoma Gastrodiae, Ganoderma Deng Yao city.
Summary of the invention
The present invention is directed to the deficiencies in the prior art, propose a kind of pharmaceutical composition, composition is various, effective.
In order to realize foregoing invention object, the invention provides following technical scheme: a kind of pharmaceutical composition, forming by the crude drug of following weight parts is brewed:
Polygonatum cyrtonema Hua 125-250 Five Ridges Herba Asari 125-250 Radix Toddaliae Asiaticae 125-250
Radix stemonae tuberosae 120-220 meropodium Auricled Hedyotis Herb 120-250 threeleaf akebia 120-220
Radix Alangii 125-250 Caulis et folium gaultheriae yunnanensis 130-210 Rhizoma Smilacis Glabrae 125-250
Herba Chenopodii 120-230 is raw pulls 120-230 Caulis Sargentodoxae 120-230
Radix Dipsaci 125-250 Fructus Fici 125-250 Herba Lycopodii 125-250.
Preferably, the weight portion of each crude drug is respectively:
Polygonatum cyrtonema Hua 175-200 Five Ridges Herba Asari 175-200 Radix Toddaliae Asiaticae 175-200
Radix stemonae tuberosae 150-190 meropodium Auricled Hedyotis Herb 160-210 threeleaf akebia 150-190
Radix Alangii 175-200 Caulis et folium gaultheriae yunnanensis 160-180 Rhizoma Smilacis Glabrae 175-200
Herba Chenopodii 160-190 is raw pulls 160-190 Caulis Sargentodoxae 160-190
Radix Dipsaci 175-200 Fructus Fici 175-200 Herba Lycopodii 175-200.
The application of pharmaceutical composition described above in the amyasthenic medicine of preparation treatment neuron amyotrophy.
A kind of pharmaceutical composition, forms by the crude drug of following weight parts is brewed:
Polygonatum cyrtonema Hua 125-250 Five Ridges Herba Asari 125-250 Radix Toddaliae Asiaticae 125-250
Radix stemonae tuberosae 120-220 meropodium Auricled Hedyotis Herb 120-250 threeleaf akebia 120-220
Radix Alangii 125-250 Caulis et folium gaultheriae yunnanensis 130-210 Rhizoma Smilacis Glabrae 125-250
Herba Chenopodii 120-230 is raw pulls 120-230 Caulis Sargentodoxae 120-230
Radix Dipsaci 125-250 Fructus Fici 125-250 Herba Lycopodii 125-250
Herba Blumeae Balsamiferae 125-250 Herba Reineckeae Carneae 125-250 Caulis et Folium piperis 125-250
Cynanchum auriculatum Royle ex Wight 120-230 Herba Kyllingae 120-230 Radix Asparagi 120-230
Herba Hylothelephii Verticillati 75-125 opens larynx sword 75-125 silk tree and opens 75-125
Rubus corchorifolius Linn. f. 75-125 Semen Caesalpiniae 75-125 Rhizoma Gastrodiae 75-125.
The application of pharmaceutical composition described above in the amyasthenic medicine of preparation treatment neuron amyotrophy.
A kind of pharmaceutical composition, forms by the crude drug of following weight parts is brewed:
Polygonatum cyrtonema Hua 125-250 Five Ridges Herba Asari 125-250 Radix Toddaliae Asiaticae 125-250
Radix stemonae tuberosae 120-220 meropodium Auricled Hedyotis Herb 120-250 threeleaf akebia 120-220
Radix Alangii 125-250 Caulis et folium gaultheriae yunnanensis 130-210 Rhizoma Smilacis Glabrae 125-250
Herba Chenopodii 120-230 is raw pulls 120-230 Caulis Sargentodoxae 120-230
Radix Dipsaci 125-250 Fructus Fici 125-250 Herba Lycopodii 125-250
Herba Blumeae Balsamiferae 125-250 Herba Reineckeae Carneae 125-250 Caulis et Folium piperis 125-250
Cynanchum auriculatum Royle ex Wight 120-230 Herba Kyllingae 120-230 Radix Asparagi 120-230
Herba Hylothelephii Verticillati 75-125 opens larynx sword 75-125 silk tree and opens 75-125
Rubus corchorifolius Linn. f. 75-125 Semen Caesalpiniae 75-125 Rhizoma Gastrodiae 75-125
Cortex Eucommiae 110-230 Ganoderma 110-230 Chinese rose 110-230
Herba Oenanthes Javanicae 130-230 Typha angustifolia 130-230 Herba Polygoni hydropiperis 130-230.
The application of pharmaceutical composition described above in the amyasthenic medicine of preparation treatment neuron amyotrophy.
A kind of pharmaceutical composition, forms by the crude drug of following weight parts is brewed:
Polygonatum cyrtonema Hua 125-250 Five Ridges Herba Asari 125-250 Radix Toddaliae Asiaticae 125-250
Radix stemonae tuberosae 120-220 meropodium Auricled Hedyotis Herb 120-250 threeleaf akebia 120-220
Radix Alangii 125-250 Caulis et folium gaultheriae yunnanensis 130-210 Rhizoma Smilacis Glabrae 125-250
Herba Chenopodii 120-230 is raw pulls 120-230 Caulis Sargentodoxae 120-230
Radix Dipsaci 125-250 Fructus Fici 125-250 Herba Lycopodii 125-250
Herba Blumeae Balsamiferae 125-250 Herba Reineckeae Carneae 125-250 Caulis et Folium piperis 125-250
Cynanchum auriculatum Royle ex Wight 120-230 Herba Kyllingae 120-230 Radix Asparagi 120-230
Herba Hylothelephii Verticillati 75-125 opens larynx sword 75-125 silk tree and opens 75-125
Rubus corchorifolius Linn. f. 75-125 Semen Caesalpiniae 75-125 Rhizoma Gastrodiae 75-125
Cortex Eucommiae 110-230 Ganoderma 110-230 Chinese rose 110-230
Herba Oenanthes Javanicae 130-230 Typha angustifolia 130-230 Herba Polygoni hydropiperis 130-230
Celestial lance 100-230 ground fruit 100-230 Broussonetia papyrifera 100-230
Folium Perillae 130-210 Oryza sativa L. var. glutinosa Matsum. 150-260 Mongolian oak Herba pteridii latiusculi 200-310.
The application of pharmaceutical composition described above in the amyasthenic medicine of preparation treatment neuron amyotrophy.
Compared with prior art, the present invention has the following advantages: adopt several wild crude drug to carry out in proportion brewed, carry out external, reach effect of inner disease outer treat.Especially to neuron amyotrophy myasthenia, there is good therapeutic effect.
Detailed description of the invention
Describe the present invention below in conjunction with embodiment, the description of this part is only exemplary and explanatory, should not have any restriction to protection scope of the present invention.
embodiment 1
A kind of pharmaceutical composition, forms by the crude drug of following weight parts is brewed:
Polygonatum cyrtonema Hua 125 Five Ridges Herba Asari 250 Radix Toddaliae Asiaticae 125 radix stemonae tuberosae 220
Meropodium Auricled Hedyotis Herb 120 threeleaf akebia 220 Radix Alangii 125 Caulis et folium gaultheriae yunnanensis 210
Rhizoma Smilacis Glabrae 125 Herba Chenopodii 230 is raw pulls 120 Caulis Sargentodoxae 230
Radix Dipsaci 125 Fructus Fici 250 Herba Lycopodii 125.
Above-mentioned raw materials medicine is proportionally used wine brewed 278 days, get clear liquid filtering-depositing, obtain supernatant.
embodiment 2
A kind of pharmaceutical composition, forms by the crude drug of following weight parts is brewed:
Polygonatum cyrtonema Hua 250 Five Ridges Herba Asari 125 Radix Toddaliae Asiaticae 250 radix stemonae tuberosae 120
Meropodium Auricled Hedyotis Herb 250 threeleaf akebia 120 Radix Alangii 250 Caulis et folium gaultheriae yunnanensis 130
Rhizoma Smilacis Glabrae 250 Herba Chenopodii 120 is raw pulls 230 Caulis Sargentodoxae 120
Radix Dipsaci 250 Fructus Fici 125 Herba Lycopodii 250.
Above-mentioned raw materials medicine is proportionally used wine brewed 278 days, get clear liquid filtering-depositing, obtain supernatant.
embodiment 3
A kind of pharmaceutical composition, forms by the crude drug of following weight parts is brewed:
Polygonatum cyrtonema Hua 175 Five Ridges Herba Asari 200 Radix Toddaliae Asiaticae 175 radix stemonae tuberosae 190
Meropodium Auricled Hedyotis Herb 160 threeleaf akebia 190 Radix Alangii 175 Caulis et folium gaultheriae yunnanensis 180
Rhizoma Smilacis Glabrae 175 Herba Chenopodii 190 is raw pulls 160 Caulis Sargentodoxae 190
Radix Dipsaci 175 Fructus Fici 200 Herba Lycopodii 175.
Above-mentioned raw materials medicine is proportionally used wine brewed 278 days, get clear liquid filtering-depositing, obtain supernatant.
embodiment 4
A kind of pharmaceutical composition, forms by the crude drug of following weight parts is brewed:
Polygonatum cyrtonema Hua 200 Five Ridges Herba Asari 175 Radix Toddaliae Asiaticae 200 radix stemonae tuberosae 150
Meropodium Auricled Hedyotis Herb 210 threeleaf akebia 150 Radix Alangii 200 Caulis et folium gaultheriae yunnanensis 160
Rhizoma Smilacis Glabrae 200 Herba Chenopodii 160 is raw pulls 190 Caulis Sargentodoxae 160
Radix Dipsaci 200 Fructus Fici 175 Herba Lycopodii 200.
Above-mentioned raw materials medicine is proportionally used wine brewed 278 days, get clear liquid filtering-depositing, obtain supernatant.
embodiment 5
A kind of pharmaceutical composition, forms by the crude drug of following weight parts is brewed:
Polygonatum cyrtonema Hua 125 Five Ridges Herba Asari 250 Radix Toddaliae Asiaticae 125 radix stemonae tuberosae 220
Meropodium Auricled Hedyotis Herb 120 threeleaf akebia 220 Radix Alangii 125 Caulis et folium gaultheriae yunnanensis 210
Rhizoma Smilacis Glabrae 125 Herba Chenopodii 230 is raw pulls 120 Caulis Sargentodoxae 230
Radix Dipsaci 125 Fructus Fici 250 Herba Lycopodii 125 Herba Blumeae Balsamiferae 250
Herba Reineckeae Carneae 125 Caulis et Folium piperis 250 cynanchum auriculatum Royle ex Wight 120 Herba Kyllingae 230
Radix Asparagi 120 Herba Hylothelephii Verticillati 125 is opened larynx sword 75 silk tree and is opened 125
Rubus corchorifolius Linn. f. 75 Semen Caesalpiniae 125 Rhizoma Gastrodiae 75.
Above-mentioned raw materials medicine is proportionally used wine brewed 278 days, get clear liquid filtering-depositing, obtain supernatant.
embodiment 6
A kind of pharmaceutical composition, forms by the crude drug of following weight parts is brewed:
Polygonatum cyrtonema Hua 250 Five Ridges Herba Asari 125 Radix Toddaliae Asiaticae 250 radix stemonae tuberosae 120
Meropodium Auricled Hedyotis Herb 250 threeleaf akebia 120 Radix Alangii 250 Caulis et folium gaultheriae yunnanensis 130
Rhizoma Smilacis Glabrae 250 Herba Chenopodii 120 is raw pulls 230 Caulis Sargentodoxae 120
Radix Dipsaci 250 Fructus Fici 125 Herba Lycopodii 250 Herba Blumeae Balsamiferae 125
Herba Reineckeae Carneae 250 Caulis et Folium piperis 125 cynanchum auriculatum Royle ex Wight 230 Herba Kyllingae 120
Radix Asparagi 230 Herba Hylothelephii Verticillati 75 is opened larynx sword 125 silk tree and is opened 75
Rubus corchorifolius Linn. f. 125 Semen Caesalpiniae 75 Rhizoma Gastrodiae 125.
Above-mentioned raw materials medicine is proportionally used wine brewed 278 days, get clear liquid filtering-depositing, obtain supernatant.
embodiment 7
A kind of pharmaceutical composition, forms by the crude drug of following weight parts is brewed:
Polygonatum cyrtonema Hua 125 Five Ridges Herba Asari 250 Radix Toddaliae Asiaticae 125 radix stemonae tuberosae 220
Meropodium Auricled Hedyotis Herb 120 threeleaf akebia 220 Radix Alangii 125 Caulis et folium gaultheriae yunnanensis 210
Rhizoma Smilacis Glabrae 125 Herba Chenopodii 230 is raw pulls 120 Caulis Sargentodoxae 230
Radix Dipsaci 125 Fructus Fici 250 Herba Lycopodii 125 Herba Blumeae Balsamiferae 250
Herba Reineckeae Carneae 125 Caulis et Folium piperis 250 cynanchum auriculatum Royle ex Wight 120 Herba Kyllingae 230
Radix Asparagi 120 Herba Hylothelephii Verticillati 125 is opened larynx sword 75 silk tree and is opened 125
Rubus corchorifolius Linn. f. 75 Semen Caesalpiniae 125 Rhizoma Gastrodiae 75 Cortex Eucommiae 230
Ganoderma 110 Chinese rose 230 Herba Oenanthes Javanicae 130 Typha angustifolia 230
Herba Polygoni hydropiperis 130.
Above-mentioned raw materials medicine is proportionally used wine brewed 278 days, get clear liquid filtering-depositing, obtain supernatant.
embodiment 8
A kind of pharmaceutical composition, forms by the crude drug of following weight parts is brewed:
Polygonatum cyrtonema Hua 250 Five Ridges Herba Asari 125 Radix Toddaliae Asiaticae 250 radix stemonae tuberosae 120
Meropodium Auricled Hedyotis Herb 250 threeleaf akebia 120 Radix Alangii 250 Caulis et folium gaultheriae yunnanensis 130
Rhizoma Smilacis Glabrae 250 Herba Chenopodii 120 is raw pulls 230 Caulis Sargentodoxae 120
Radix Dipsaci 250 Fructus Fici 125 Herba Lycopodii 250 Herba Blumeae Balsamiferae 125
Herba Reineckeae Carneae 250 Caulis et Folium piperis 125 cynanchum auriculatum Royle ex Wight 230 Herba Kyllingae 120
Radix Asparagi 230 Herba Hylothelephii Verticillati 75 is opened larynx sword 125 silk tree and is opened 75
Rubus corchorifolius Linn. f. 125 Semen Caesalpiniae 75 Rhizoma Gastrodiae 125 Cortex Eucommiae 110
Ganoderma 230 Chinese rose 110 Herba Oenanthes Javanicae 230 Typha angustifolia 130
Herba Polygoni hydropiperis 230.
Above-mentioned raw materials medicine is proportionally used wine brewed 278 days, get clear liquid filtering-depositing, obtain supernatant.
embodiment 9
A kind of pharmaceutical composition, forms by the crude drug of following weight parts is brewed:
Polygonatum cyrtonema Hua 125 Five Ridges Herba Asari 250 Radix Toddaliae Asiaticae 125 radix stemonae tuberosae 220
Meropodium Auricled Hedyotis Herb 120 threeleaf akebia 220 Radix Alangii 125 Caulis et folium gaultheriae yunnanensis 210
Rhizoma Smilacis Glabrae 125 Herba Chenopodii 230 is raw pulls 120 Caulis Sargentodoxae 230
Radix Dipsaci 125 Fructus Fici 250 Herba Lycopodii 125 Herba Blumeae Balsamiferae 250
Herba Reineckeae Carneae 125 Caulis et Folium piperis 250 cynanchum auriculatum Royle ex Wight 120 Herba Kyllingae 230
Radix Asparagi 120 Herba Hylothelephii Verticillati 125 is opened larynx sword 75 silk tree and is opened 125
Rubus corchorifolius Linn. f. 75 Semen Caesalpiniae 125 Rhizoma Gastrodiae 75 Cortex Eucommiae 230
Ganoderma 110 Chinese rose 230 Herba Oenanthes Javanicae 130 Typha angustifolia 230
Herba Polygoni hydropiperis 130 celestial lance 230 ground fruit 100 Broussonetia papyriferas 230
Folium Perillae 130 Oryza sativa L. var. glutinosa Matsum. 260 Mongolian oak Herba pteridii latiusculi 310.
Above-mentioned raw materials medicine is proportionally used wine brewed 278 days, get clear liquid filtering-depositing, obtain supernatant.
embodiment 10
A kind of pharmaceutical composition, forms by the crude drug of following weight parts is brewed:
Polygonatum cyrtonema Hua 250 Five Ridges Herba Asari 125 Radix Toddaliae Asiaticae 250 radix stemonae tuberosae 120
Meropodium Auricled Hedyotis Herb 250 threeleaf akebia 120 Radix Alangii 250 Caulis et folium gaultheriae yunnanensis 130
Rhizoma Smilacis Glabrae 250 Herba Chenopodii 120 is raw pulls 230 Caulis Sargentodoxae 120
Radix Dipsaci 250 Fructus Fici 125 Herba Lycopodii 250 Herba Blumeae Balsamiferae 125
Herba Reineckeae Carneae 250 Caulis et Folium piperis 125 cynanchum auriculatum Royle ex Wight 230 Herba Kyllingae 120
Radix Asparagi 230 Herba Hylothelephii Verticillati 75 is opened larynx sword 125 silk tree and is opened 75
Rubus corchorifolius Linn. f. 125 Semen Caesalpiniae 75 Rhizoma Gastrodiae 125 Cortex Eucommiae 110
Ganoderma 230 Chinese rose 110 Herba Oenanthes Javanicae 230 Typha angustifolia 130
Herba Polygoni hydropiperis 230 celestial lance 100 ground fruit 230 Broussonetia papyriferas 100
Folium Perillae 210 Oryza sativa L. var. glutinosa Matsum. 150 Mongolian oak Herba pteridii latiusculi 310.
Above-mentioned raw materials medicine is proportionally used wine brewed 278 days, get clear liquid filtering-depositing, obtain supernatant.
embodiment 11
A kind of pharmaceutical composition, forms by the crude drug of following weight parts is brewed:
Polygonatum cyrtonema Hua 183 Five Ridges Herba Asari 183 Radix Toddaliae Asiaticae 183 radix stemonae tuberosae 170
Meropodium Auricled Hedyotis Herb 175 threeleaf akebia 170 Radix Alangii 183 Caulis et folium gaultheriae yunnanensis 170
Rhizoma Smilacis Glabrae 183 Herba Chenopodii 175 is raw pulls 175 Caulis Sargentodoxae 175
Radix Dipsaci 183 Fructus Fici 183 Herba Lycopodii 183 Herba Blumeae Balsamiferae 183
Herba Reineckeae Carneae 183 Caulis et Folium piperis 183 cynanchum auriculatum Royle ex Wight 175 Herba Kyllingae 175
Radix Asparagi 175 Herba Hylothelephii Verticillati 100 is opened larynx sword 100 silk tree and is opened 100
Rubus corchorifolius Linn. f. 100 Semen Caesalpiniae 100 Rhizoma Gastrodiae 100 Cortex Eucommiae 170
Ganoderma 170 Chinese rose 170 Herba Oenanthes Javanicae 180 Typha angustifolia 180
Herba Polygoni hydropiperis 180 celestial lance 165 ground fruit 165 Broussonetia papyriferas 165
Folium Perillae 170 Oryza sativa L. var. glutinosa Matsum. 205 Mongolian oak Herba pteridii latiusculi 255.
Above-mentioned raw materials medicine is proportionally used wine brewed 278 days, get clear liquid filtering-depositing, obtain supernatant.
Medication: get " Miao Ethnomedicine liquid pain easing medicine " tincture 50 to 269 milliliters according to individual physique feature and the clinical state of an illness and act on the acupuncture points on the human body meridians (mainly diseased region and neuron amyotrophy root place's administration relaxing muscles and tendons attack a vital point conditioning) causing patient's amyotrophy serious, scorching hot and the diseases caused by exogenous pathogenic factor skin table toxin expelling cold expelling of patient's self-induction, once a day.
Treatment situation:
1, clinical cure: the muscle recovery at amyotrophy position is normal, with strong side limbs no significant difference.
2, effective: the muscle 7 to 20 minutes at first time conditioning amyotrophy position, comparatively before conditioning obviously long get up 1.5-5.5 centimeters, normal circulation of qi and blood, muscular strength increase.
3, effective: the muscle of edematous site comparatively treats front detumescence 1.5-5.5cm.
4, invalid: the muscle at amyotrophy position is comparatively treated front unchanged.
Adopt pharmaceutical composition of the present invention, according to 5779 routine curative effect statistics: man 4326 example, female 1453 example.
Result: effective 4201 examples, account for 72.7%; Effective 1578 examples, account for 27.3%; Invalid 0 example, total effective rate 100%.
Model case
1, Zhang, female, 16 years old, the second half year in 2006, left lower extremity started to occur the symptoms such as unable, stiff, and after 15 days, right lower extremity also starts to occur same symptom, causes handicapped.Be diagnosed as through hospital: nongenetic motor neuron (amyotrophic lateral sclerosis).But fail to respond to any medical treatment, doctor informs that child lives only 18 years old.
Patient accepts medicine external treatment of the present invention on July 5th, 2008, both hands muscle of thenar and finger muscles atrophy is seen during health check-up, two upper limb muscular tension slightly increases, two lower limb lift painstakingly, " lie on the back and raise, both feet are followed from bed 11 centimeters, time with tic and Weizhong point severe cramps; flesh Zhang Wuli obviously increases, and left side is more obvious.
On July 5th, 2008 to August 5, left lower limb Zusanli point place amyotrophy was 27 centimeters by treating the dialectical conditioning of making up a prescription of patient, and measuring by 27 centimeters long before nursing one's health after using medicinal liquid of the present invention to transfer to other localities 15 minutes is 31.5 centimeters.Be 27.5 centimeters before the conditioning of right lower limb Zusanli point place, uses medicinal liquid of the present invention to add the conditioning of attacking a vital point of acupuncture points on the human body relaxing muscles and tendons and be measured as 32 centimeters after 15 minutes, after the investigation mission outside the city or town of both legs first time Miao Ethnomedicine liquid, muscles of leg atrophy respectively length gets up 4.5 centimeters.Patient back, the serious rickets of breastbone, thoracic cavity back all clavicle, be spaced apart 18 centimeters between ZHONGWAN acupoint and QUGU acupoint.The serious deformation of unevenness of rib bone.General amyotrophy is obviously abnormal.After first time conditioning, the ZHONGWAN acupoint of patient and QUGU acupoint trail as 23 centimeters before nursing one's health.Patient also feels that breathing is not easily felt suffocated, not uncomfortable in chest.
This case carries out medicinal liquid investigation mission outside the city or town once every day, walks abreast and suitably carries out rehabilitation training.Two courses for the treatment of, within 30 days, when leaving hospital, extremity are strong, do not need people to assist in and crutch, one kilometer of distance of can oneself walking alone, muscular strength and muscle length get up substantially to revert to normal condition, oneself can also stair activity alone, strong before double-grip comparatively, substantially recover self care ability.Within continuous 4 years, follow the tracks of and pay a return visit, without recurrence sign.
2, Zhao: man, 17 years old, the second half year in 2008, right lower extremity started to occur the symptoms such as unable, stiff, and after 3 days, left lower extremity also starts to occur same symptom, causes handicapped.Through hospital diagnosis be: posteriority " motor neuron cell is sick ", (amyotrophic lateral sclerosis).But fail to respond to any medical treatment and turn the large hospital in Shanghai, patient describes the well-known Chinese and western medicine in the similar whole nation and has seen, but does not all see curative effect.And the state of an illness is controlled more serious and more serious, introduce through its relatives, the expert of hospital informs that child lives only 18 years old.
Patient accepts medicinal liquid external treatment of the present invention on October 12nd, 2009, when being admitted to hospital, health check-up is shown in that both hands can not be praised, shou wu li and shou san li muscle and muscle of thenar and palm, finger muscles whole body amyotrophy, both hands tension force can not raise embrace a head, two lower limb lift painstakingly, " lie on the back and raise; both feet are followed from bed 7 centimeters; both thighs, muscles of leg atrophy, time with twitch and Weizhong point severe cramps, flesh Zhang Wuli obviously increases, and right side is more obvious.
Right lower limb Zusanli point place amyotrophy is 26.5 centimeters, and measuring 27 centimeters long before having conditioning after using medicinal liquid of the present invention to transfer to other localities 20 minutes is 31.5 centimeters.It is 26 centimeters before the conditioning of right lower limb Zusanli point place, after using medicinal liquid of the present invention to transfer to other localities 18 minutes, repeated measure by 26 before nursing one's health long get up be 31 centimeters, both legs first time use Miao Ethnomedicine liquid is attacked a vital point in conjunction with Seedling medical technologies method acupuncture points on the human body relaxing muscles and tendons after investigation mission outside the city or town, and both legs amyotrophy Zusanli point place respectively length gets up 5 centimeters.All whole body amyotrophy is serious for arm and thoracic cavity back.Use medicinal liquid of the present invention in conjunction with after the conditioning of Seedling medical technologies energy acupuncture points on the human body channels and collaterals acupoint, each position obtains clearly length.First time conditioning does not also terminate patient and just says: sensation is breathed light, does not feel suffocated, not uncomfortable in chest, not irritated.
This case carries out a Miao Ethnomedicine liquid technical ability investigation mission outside the city or town every day, parallel suitably carry out rehabilitation training according to patient's body constitution, on October 12nd, 2008 to November 27, by treating 3 courses for the treatment of to the dialectical conditioning of making up a prescription of patient, 45 when leaving hospital everyday, extremity are strong, do not need people to assist in and crutch, one kilometer of multichannel journey of can oneself walking alone, muscular strength and muscle length get up substantially to revert to normal condition, oneself can also stair activity alone, strong before double-grip comparatively, substantially recover self care ability.Pass by 4 years, patient is more than 18 one full year of life more.And that can take care of oneself lives.
 
Pharmaceutical composition of the present invention is pure Chinese medicinal preparation, plays the external Miao medicine of targeted therapy disease mainly through the dirty absorption of human body surface skin.Break up with broken joint, blood circulation promoting and blood stasis dispelling, row's stasis of blood toxin expelling, qi-supplementing, blood-engendering, dredging the meridian, strengthening vital QI to eliminate pathogenic factors, invigorating middle warmer lung moistening etc., clear excretion benefit combines together mediator's body immunity function and repairing fast visceral system damage, thus reaches effect of inner disease outer treat.Especially of flaccid muscles to amyotrophy and inside and outside damage etc. has good therapeutic effect.Prescription of the present invention forms by 39 taste pure natural natural crude drugs are brewed in proportion, and external is therefore without any side effects.
The above is only the preferred embodiment of the present invention; it should be pointed out that for those skilled in the art, under the premise without departing from the principles of the invention; can also make some improvements and modifications, these improvements and modifications also should be considered as protection scope of the present invention.

Claims (9)

1. a pharmaceutical composition, forms by the crude drug of following weight parts is brewed:
Polygonatum cyrtonema Hua 125-250 Five Ridges Herba Asari 125-250 Radix Toddaliae Asiaticae 125-250
Radix stemonae tuberosae 120-220 meropodium Auricled Hedyotis Herb 120-250 threeleaf akebia 120-220
Radix Alangii 125-250 Caulis et folium gaultheriae yunnanensis 130-210 Rhizoma Smilacis Glabrae 125-250
Herba Chenopodii 120-230 is raw pulls 120-230 Caulis Sargentodoxae 120-230
Radix Dipsaci 125-250 Fructus Fici 125-250 Herba Lycopodii 125-250.
2. pharmaceutical composition as claimed in claim 1, is characterized in that: the weight portion of each crude drug is respectively:
Polygonatum cyrtonema Hua 175-200 Five Ridges Herba Asari 175-200 Radix Toddaliae Asiaticae 175-200
Radix stemonae tuberosae 150-190 meropodium Auricled Hedyotis Herb 160-210 threeleaf akebia 150-190
Radix Alangii 175-200 Caulis et folium gaultheriae yunnanensis 160-180 Rhizoma Smilacis Glabrae 175-200
Herba Chenopodii 160-190 is raw pulls 160-190 Caulis Sargentodoxae 160-190
Radix Dipsaci 175-200 Fructus Fici 175-200 Herba Lycopodii 175-200.
3. the application of pharmaceutical composition in the amyasthenic medicine of preparation treatment neuron amyotrophy as claimed in claim 1 or 2.
4. a pharmaceutical composition, forms by the crude drug of following weight parts is brewed:
Polygonatum cyrtonema Hua 125-250 Five Ridges Herba Asari 125-250 Radix Toddaliae Asiaticae 125-250
Radix stemonae tuberosae 120-220 meropodium Auricled Hedyotis Herb 120-250 threeleaf akebia 120-220
Radix Alangii 125-250 Caulis et folium gaultheriae yunnanensis 130-210 Rhizoma Smilacis Glabrae 125-250
Herba Chenopodii 120-230 is raw pulls 120-230 Caulis Sargentodoxae 120-230
Radix Dipsaci 125-250 Fructus Fici 125-250 Herba Lycopodii 125-250
Herba Blumeae Balsamiferae 125-250 Herba Reineckeae Carneae 125-250 Caulis et Folium piperis 125-250
Cynanchum auriculatum Royle ex Wight 120-230 Herba Kyllingae 120-230 Radix Asparagi 120-230
Herba Hylothelephii Verticillati 75-125 opens larynx sword 75-125 silk tree and opens 75-125
Rubus corchorifolius Linn. f. 75-125 Semen Caesalpiniae 75-125 Rhizoma Gastrodiae 75-125.
5. the application of pharmaceutical composition in the amyasthenic medicine of preparation treatment neuron amyotrophy as claimed in claim 4.
6. a pharmaceutical composition, forms by the crude drug of following weight parts is brewed:
Polygonatum cyrtonema Hua 125-250 Five Ridges Herba Asari 125-250 Radix Toddaliae Asiaticae 125-250
Radix stemonae tuberosae 120-220 meropodium Auricled Hedyotis Herb 120-250 threeleaf akebia 120-220
Radix Alangii 125-250 Caulis et folium gaultheriae yunnanensis 130-210 Rhizoma Smilacis Glabrae 125-250
Herba Chenopodii 120-230 is raw pulls 120-230 Caulis Sargentodoxae 120-230
Radix Dipsaci 125-250 Fructus Fici 125-250 Herba Lycopodii 125-250
Herba Blumeae Balsamiferae 125-250 Herba Reineckeae Carneae 125-250 Caulis et Folium piperis 125-250
Cynanchum auriculatum Royle ex Wight 120-230 Herba Kyllingae 120-230 Radix Asparagi 120-230
Herba Hylothelephii Verticillati 75-125 opens larynx sword 75-125 silk tree and opens 75-125
Rubus corchorifolius Linn. f. 75-125 Semen Caesalpiniae 75-125 Rhizoma Gastrodiae 75-125
Cortex Eucommiae 110-230 Ganoderma 110-230 Chinese rose 110-230
Herba Oenanthes Javanicae 130-230 Typha angustifolia 130-230 Herba Polygoni hydropiperis 130-230.
7. the application of pharmaceutical composition in the amyasthenic medicine of preparation treatment neuron amyotrophy as claimed in claim 6.
8. a pharmaceutical composition, forms by the crude drug of following weight parts is brewed:
Polygonatum cyrtonema Hua 125-250 Five Ridges Herba Asari 125-250 Radix Toddaliae Asiaticae 125-250
Radix stemonae tuberosae 120-220 meropodium Auricled Hedyotis Herb 120-250 threeleaf akebia 120-220
Radix Alangii 125-250 Caulis et folium gaultheriae yunnanensis 130-210 Rhizoma Smilacis Glabrae 125-250
Herba Chenopodii 120-230 is raw pulls 120-230 Caulis Sargentodoxae 120-230
Radix Dipsaci 125-250 Fructus Fici 125-250 Herba Lycopodii 125-250
Herba Blumeae Balsamiferae 125-250 Herba Reineckeae Carneae 125-250 Caulis et Folium piperis 125-250
Cynanchum auriculatum Royle ex Wight 120-230 Herba Kyllingae 120-230 Radix Asparagi 120-230
Herba Hylothelephii Verticillati 75-125 opens larynx sword 75-125 silk tree and opens 75-125
Rubus corchorifolius Linn. f. 75-125 Semen Caesalpiniae 75-125 Rhizoma Gastrodiae 75-125
Cortex Eucommiae 110-230 Ganoderma 110-230 Chinese rose 110-230
Herba Oenanthes Javanicae 130-230 Typha angustifolia 130-230 Herba Polygoni hydropiperis 130-230
Celestial lance 100-230 ground fruit 100-230 Broussonetia papyrifera 100-230
Folium Perillae 130-210 Oryza sativa L. var. glutinosa Matsum. 150-260 Mongolian oak Herba pteridii latiusculi 200-310.
9. the application of pharmaceutical composition in the amyasthenic medicine of preparation treatment neuron amyotrophy as claimed in claim 8.
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