CN104288467A - Medicine composition for treating rheumatoid arthritis for nursing department - Google Patents
Medicine composition for treating rheumatoid arthritis for nursing department Download PDFInfo
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- CN104288467A CN104288467A CN201410612219.7A CN201410612219A CN104288467A CN 104288467 A CN104288467 A CN 104288467A CN 201410612219 A CN201410612219 A CN 201410612219A CN 104288467 A CN104288467 A CN 104288467A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/27—Asclepiadaceae (Milkweed family), e.g. hoya
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/51—Gentianaceae (Gentian family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/66—Papaveraceae (Poppy family), e.g. bloodroot
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8962—Allium, e.g. garden onion, leek, garlic or chives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization
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Abstract
The invention relates to a medicine composition for treating rheumatoid arthritis for a nursing department. The medicine composition is prepared from the following raw material medicines in parts by weight: 50-100 parts of sabia parviflora, 50-120 parts of roots of rosa cymosa tratt, 50-150 parts of ecristate corydalis herbs, 50-100 parts of rubus amphidasys focke, 50-100 parts of elongated swertia herbs, 50-200 parts of rubus phoenicolasius maxim, 100-150 parts of himalayan willowweed herbs, 50-100 parts of dominant pulicaria flowers, 50-100 parts of linearleaf thustle roots, 50-100 parts of dregea sinensis hemsl, 50-100 parts of chives, and 10-100 parts of roots of perny germander. The medicine composition for treating the rheumatoid arthritis for the nursing department, disclosed by the invention, has the characteristics of reasonable formula, precise curative effects, security, convenience, no toxic or side effects, and low price.
Description
Technical field
The present invention relates to field of medicaments, relate in particular to the pharmaceutical composition of a kind of section of nursing treatment rheumatoid arthritis.
Background technology
Rheumatoid arthritis (RA) belongs to Chinese medical ' arthralgia syndrome ' scope, is a kind ofly to accompany pathological changes (pericarditis, pleuritis, pneumonia, peripheral neuritis, subcutaneous nodule) outside chronic, symmetry, the multiple Minor articulus inflammatory disorders of acute attack and joint for the not bright immune disease of the reason of main clinical manifestation.Current western medicine rheumatoid arthritis poor effect.
Summary of the invention
The object of this invention is to provide the pharmaceutical composition of a kind of section of nursing treatment rheumatoid arthritis.
In order to realize object of the present invention, the invention provides the pharmaceutical composition of a kind of section of nursing treatment rheumatoid arthritis, it is made up by weight of following bulk drugs: Sabia parviflora Wall.ex Roxb 50-100 part, Smallfruit Rose Root root 50-120 part, Herba Corydalis tailensis 50-150 part, peritricha Fructus Rubi corchorifolii Immaturus 50-100 part, Herba Swertiae davidi 50-100 part, empty cylinder steep 50-200 part, Herba Epilobii Himalayensis 100-150 part, Pulicaria insignis Drumm. 50-100 part, Herba Cirsii linearis 50-100 part, pass through muscle rattan 50-100 part, Herba Allii Schoenoprasi 50-100 part and Radix Teucrii Pernyi 10-100 part.
Preferably, the pharmaceutical composition of nursing section of the present invention treatment rheumatoid arthritis is made up by weight of following bulk drugs: Sabia parviflora Wall.ex Roxb 75 parts, Smallfruit Rose Root root 90 parts, Herba Corydalis tailensis 100 parts, peritricha Fructus Rubi corchorifolii Immaturus 80 parts, Herba Swertiae davidi 70 parts, empty cylinder steep 100 parts, Herba Epilobii Himalayensis 110 parts, Pulicaria insignis Drumm. 80 parts, Herba Cirsii linearis 90 parts, pass through 70 parts, muscle rattan, Herba Allii Schoenoprasi 70 parts and Radix Teucrii Pernyi 50 parts.
Preferably, described pharmaceutical composition can be tablet, dispersible tablet, disintegrating tablet, rapidly dissolving tablet, enteric coatel tablets, patch or ointment.
The present invention also provides the purposes of compositions in the medicine of preparation nursing section treatment rheumatoid arthritis, and described compositions is made up by weight of following bulk drugs: Sabia parviflora Wall.ex Roxb 50-100 part, Smallfruit Rose Root root 50-120 part, Herba Corydalis tailensis 50-150 part, peritricha Fructus Rubi corchorifolii Immaturus 50-100 part, Herba Swertiae davidi 50-100 part, empty cylinder steep 50-200 part, Herba Epilobii Himalayensis 100-150 part, Pulicaria insignis Drumm. 50-100 part, Herba Cirsii linearis 50-100 part, pass through muscle rattan 50-100 part, Herba Allii Schoenoprasi 50-100 part and Radix Teucrii Pernyi 10-100 part.
Preferably, described compositions is made up by weight of following bulk drugs: Sabia parviflora Wall.ex Roxb 75 parts, Smallfruit Rose Root root 90 parts, Herba Corydalis tailensis 100 parts, peritricha Fructus Rubi corchorifolii Immaturus 80 parts, Herba Swertiae davidi 70 parts, empty cylinder steep 100 parts, Herba Epilobii Himalayensis 110 parts, Pulicaria insignis Drumm. 80 parts, Herba Cirsii linearis 90 parts, pass through 70 parts, muscle rattan, Herba Allii Schoenoprasi 70 parts and Radix Teucrii Pernyi 50 parts.
Preferably, described medicine can be tablet, dispersible tablet, disintegrating tablet, rapidly dissolving tablet, enteric coatel tablets, patch or ointment.
Generally acknowledged that " organic conception ", " determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs ", " compound recipe use ", " compound compatibility medication is as used military forces " are the traditional Chinese medical science the most effective most scientific several large advantages at present, wherein " compound compatibility medication is as used military forces " is the original theory of Chinese medicine of very science.The tight compatibility that in traditional Chinese medical science prescription, each medicine is all linked with one another as arrayed troops for battle is that it is better than the effective means of Western medicine formula.Tcm prescription theory is thought, each prescription, not only need to select the appropriate compatibility of suitable pharmaceutical composition according to etiology and pathogenesis, also should meet the basic structure of prescription simultaneously, the i.e. prescription compatibility theory of " monarch, minister, help, make ", the prescription compatibility of so-called " monarch, minister, help, make " is exactly that it is based upon the scientific matching on the comprehensive judgement basis of disease pathogenesis.In medical side by too many levels, Mutiple Targets Integrate adjustment biological mechanism, can to obtain than Western medicine more lastingly, the more therapeutic effect that has no side effect of green natural, and this curative effect be based upon the above-mentioned traditional Chinese medical science tradition original theory accurate instruction on, the present invention just have followed this principle.
In the present invention, Sabia parviflora Wall.ex Roxb and Smallfruit Rose Root root are monarch drug; Herba Corydalis tailensis, peritricha Fructus Rubi corchorifolii Immaturus, Herba Swertiae davidi, empty cylinder bubble is ministerial drug; Herba Epilobii Himalayensis, Pulicaria insignis Drumm., Herba Cirsii linearis, pass through muscle rattan, Herba Allii Schoenoprasi is adjuvant drug; Radix Teucrii Pernyi coordinating the actions of various ingredients in a prescription, plays the effect making medicine in the compositions of the present invention.All medicines are harmonious in the present invention, reasonable recipe, have determined curative effect, safe ready, have no side effect, cheap feature.
Detailed description of the invention
The present invention is further illustrated below by embodiment.It should be understood that embodiments of the invention are for illustration of the present invention instead of limitation of the present invention.Essence according to the present invention all belongs to the scope of protection of present invention to the simple modifications that the present invention carries out.Unless otherwise stated, the percent in the present invention is percetage by weight.
Embodiment ointment of the present invention
Take Sabia parviflora Wall.ex Roxb 75 grams, Smallfruit Rose Root root 90 grams, Herba Corydalis tailensis 100 grams, peritricha Fructus Rubi corchorifolii Immaturus 80 grams, Herba Swertiae davidi 70 grams, empty cylinder steeps 100 grams, Herba Epilobii Himalayensis 110 grams, Pulicaria insignis Drumm. 80 grams, Herba Cirsii linearis 90 grams, pass through 70 grams, muscle rattan, Herba Allii Schoenoprasi 70 grams and Radix Teucrii Pernyi 50 grams, add 8 liters, water, heating 3 hours under the condition of backflow, filter, relative density 1.20 at filtrate being concentrated into 55 DEG C, ZLPG6-10 spray dryer (Jiangsu Fan Qun drying equipment factory) is used to be 115 DEG C in inlet temperature, infusion pump rotating speed is carry out spraying dry under the condition of 25r/min, thus obtain dried powder, lanoline 100 grams is added in above-mentioned powder, be stirred into paste, be dispensed in 250 flexible pipes, obtain ointment of the present invention.
Experimental example
Select 80 routine rheumatisants, man 40 example, female 40 example, the mean age is 58 years old.Diagnostic criteria: the standard formulated with reference to " American Rheumatism Association ", that is: according to medical history, physical diagnosis and radiological examination result: knee-joint pain, namely 3 of simultaneously possessing in following 6 conditions determine clinical diagnosis, and 1. radiology shows hyperosteogeny formation; 2. rise morning and be stiffly less than 30 minutes; 3. bone sound is had during joint motion; 4. knee joint bone increases; 5. bone tenderness is had; 6. heat up without obvious synovial membrane.
The ointment using embodiment to prepare is treated, and every day 3 times, at every turn for sore place, every square centimeter of uniform application 1 gram of ointment, treating 10 days is 1 course for the treatment of.Painful area skin has redness, festers, pimple person's forbidding.
Efficacy determination: effective: gonalgia transference cure, morning stiff time shorten or stiff without morning, physico-chemical examination is normal.Take a turn for the better: gonalgia symptom alleviates, and physico-chemical examination makes moderate progress.Invalid: the gonalgia is without alleviating, and physico-chemical examination is without change.
Therapeutic outcome
Through the treatment of a course for the treatment of, find in 80 routine patients, effective 61 examples, take a turn for the better 19 examples, and total effective rate is 100%.
Untoward reaction and toxic and side effects supervision
By detect patient blood pressure, pulse, whether there is Nausea and vomiting, dizzy clinical symptoms judges untoward reaction.Find that the systolic pressure of 80 routine patients is between 90-140mmHg, diastolic pressure is between 60-90mmHg, and pulse is 60-100 beat/min, and blood pressure and pulse all within normal range, and does not occur Nausea and vomiting, dizzy clinical symptoms.This illustrates that pharmaceutical composition of the present invention does not have obvious untoward reaction, and then proves that medicine does not have obvious toxic and side effects for human body.
Claims (6)
1. the pharmaceutical composition of the section's of nursing treatment rheumatoid arthritis, it is characterized in that, it is made up by weight of following bulk drugs: Sabia parviflora Wall.ex Roxb 50-100 part, Smallfruit Rose Root root 50-120 part, Herba Corydalis tailensis 50-150 part, peritricha Fructus Rubi corchorifolii Immaturus 50-100 part, Herba Swertiae davidi 50-100 part, empty cylinder steep 50-200 part, Herba Epilobii Himalayensis 100-150 part, Pulicaria insignis Drumm. 50-100 part, Herba Cirsii linearis 50-100 part, pass through muscle rattan 50-100 part, Herba Allii Schoenoprasi 50-100 part and Radix Teucrii Pernyi 10-100 part.
2. the pharmaceutical composition of nursing section according to claim 1 treatment rheumatoid arthritis, it is characterized in that, it is made up by weight of following bulk drugs: Sabia parviflora Wall.ex Roxb 75 parts, Smallfruit Rose Root root 90 parts, Herba Corydalis tailensis 100 parts, peritricha Fructus Rubi corchorifolii Immaturus 80 parts, Herba Swertiae davidi 70 parts, empty cylinder steep 100 parts, Herba Epilobii Himalayensis 110 parts, Pulicaria insignis Drumm. 80 parts, Herba Cirsii linearis 90 parts, pass through 70 parts, muscle rattan, Herba Allii Schoenoprasi 70 parts and Radix Teucrii Pernyi 50 parts.
3. the pharmaceutical composition of nursing section according to claim 1 treatment rheumatoid arthritis, it is characterized in that, described pharmaceutical composition can be tablet, dispersible tablet, disintegrating tablet, rapidly dissolving tablet, enteric coatel tablets, patch or ointment.
4. the purposes of compositions in the medicine of preparation nursing section treatment rheumatoid arthritis, it is characterized in that, described compositions is made up by weight of following bulk drugs: Sabia parviflora Wall.ex Roxb 50-100 part, Smallfruit Rose Root root 50-120 part, Herba Corydalis tailensis 50-150 part, peritricha Fructus Rubi corchorifolii Immaturus 50-100 part, Herba Swertiae davidi 50-100 part, empty cylinder steep 50-200 part, Herba Epilobii Himalayensis 100-150 part, Pulicaria insignis Drumm. 50-100 part, Herba Cirsii linearis 50-100 part, pass through muscle rattan 50-100 part, Herba Allii Schoenoprasi 50-100 part and Radix Teucrii Pernyi 10-100 part.
5. purposes according to claim 4, it is characterized in that, described compositions is made up by weight of following bulk drugs: Sabia parviflora Wall.ex Roxb 75 parts, Smallfruit Rose Root root 90 parts, Herba Corydalis tailensis 100 parts, peritricha Fructus Rubi corchorifolii Immaturus 80 parts, Herba Swertiae davidi 70 parts, empty cylinder steep 100 parts, Herba Epilobii Himalayensis 110 parts, Pulicaria insignis Drumm. 80 parts, Herba Cirsii linearis 90 parts, pass through 70 parts, muscle rattan, Herba Allii Schoenoprasi 70 parts and Radix Teucrii Pernyi 50 parts.
6. purposes according to claim 4, is characterized in that, described medicine can be tablet, dispersible tablet, disintegrating tablet, rapidly dissolving tablet, enteric coatel tablets, patch or ointment.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410612219.7A CN104288467A (en) | 2014-11-03 | 2014-11-03 | Medicine composition for treating rheumatoid arthritis for nursing department |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410612219.7A CN104288467A (en) | 2014-11-03 | 2014-11-03 | Medicine composition for treating rheumatoid arthritis for nursing department |
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| CN104288467A true CN104288467A (en) | 2015-01-21 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201410612219.7A Pending CN104288467A (en) | 2014-11-03 | 2014-11-03 | Medicine composition for treating rheumatoid arthritis for nursing department |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104587273A (en) * | 2015-02-13 | 2015-05-06 | 谢士成 | Medicinal composition for treating knee osteoarthritis |
| GB2558275A (en) * | 2016-12-23 | 2018-07-11 | Naturex Sa | Compositions |
Citations (2)
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| JPH04243832A (en) * | 1991-01-22 | 1992-08-31 | Kanebo Ltd | Treating agent for autoimmune disease |
| CN103860786A (en) * | 2014-03-28 | 2014-06-18 | 李燕 | Medicine for treating puerperal fever |
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2014
- 2014-11-03 CN CN201410612219.7A patent/CN104288467A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH04243832A (en) * | 1991-01-22 | 1992-08-31 | Kanebo Ltd | Treating agent for autoimmune disease |
| CN103860786A (en) * | 2014-03-28 | 2014-06-18 | 李燕 | Medicine for treating puerperal fever |
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| 南京中医药大学: "《中药大辞典》", 30 June 2014, 上海科学技术出版社 * |
| 王祥飞: "类风湿性关节炎的中医辨证施护", 《护士进修杂志》 * |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104587273A (en) * | 2015-02-13 | 2015-05-06 | 谢士成 | Medicinal composition for treating knee osteoarthritis |
| GB2558275A (en) * | 2016-12-23 | 2018-07-11 | Naturex Sa | Compositions |
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Application publication date: 20150121 |