CN104288399A - 一种治疗牛皮癣的药物及其制备方法 - Google Patents

一种治疗牛皮癣的药物及其制备方法 Download PDF

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CN104288399A
CN104288399A CN201410531860.8A CN201410531860A CN104288399A CN 104288399 A CN104288399 A CN 104288399A CN 201410531860 A CN201410531860 A CN 201410531860A CN 104288399 A CN104288399 A CN 104288399A
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李俊平
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/285—Aucklandia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/618—Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/17—Gnetophyta, e.g. Ephedraceae (Mormon-tea family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484—Glycyrrhiza (licorice)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/752—Citrus, e.g. lime, orange or lemon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
    • A61K36/8888—Pinellia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps

Abstract

本发明为一种治疗牛皮癣的药物，其主要以木香、青皮、麻黄、半夏、石决明和甘草中草药为原料，通过文火反复煎熬，然后取出药渣，将药液混合放入砂锅煎2—4小时，将药液浓缩成稠膏状，然后加入常规辅料，制成临床接受的药剂包装后得成品。本发明药物清热解毒、消炎敛疮，可以治疗各种类型牛皮癣。

Description

一种治疗牛皮癣的药物及其制备方法
技术领域
本发明涉及到一种治疗牛皮癣的药物，特别涉及到一种以中草药为原料制备的治疗牛皮癣的药物，本发明还涉及该药物的制备方法。
背景技术
牛皮癣又称银屑病，是一种较常见的皮肤病，慢性易于复发，并具有炎症性。主要症状是皮肤有白色鳞屑、发亮薄膜和点状出血等。牛皮癣非常顽固，很难治愈，目前，治疗牛皮癣的西药很多，但普遍具有治疗成本高、副作用大等缺点。另外，还有很多治疗牛皮癣的中药，但大多数具有治疗效果差、治疗周期长等缺点。还有许多诸如紫外线疗法、激光疗法等物理治疗方法，其费用高、周期长。
发明内容
本发明旨在提供一种治愈率高、治疗成本低、无毒副作用的治疗牛皮癣的药物。
提供该药物的制备方法是本发明的另一发明目的。
本发明的药物是由下述质量比例的原料制成：
        木  香5-13        青  皮10-15
麻  黄8-22       半  夏10-25   
石决明7-20       甘  草6-15
具体由下述质量比例的原料制成：
        木  香8           青  皮12
麻  黄16          半  夏20   
石决明10          甘  草14
本发明药物的制备方法是：
将木香、青皮、麻黄、半夏、石决明和甘草加入60—100重量份的清水，文火煎0.5—1.5小时，反复煎3次后，取出药渣，将3次药液混合放入砂锅煎2—4小时，将药液浓缩成稠膏状，然后加入常规辅料，制成临床接受的药剂。
本发明组方中各药间有相加互补和协同作用，清热解毒、消炎敛疮，可以治疗各种类型牛皮癣，且无毒副作用。
本发明是发明人经过反复研究，逐步改进，最后成功的一种疗效较好的治疗牛皮癣的药物，为表明本发明药物对牛皮癣的治疗效果，本发明对170例服用本药物的牛皮癣患者进行了临床观察，并选择具有可比性的牛皮癣患者169例作为对照组。治疗组患者每天服用本发明药物三次，早中晚各一次，一次服用5克药物，对照组患者服用常规治疗牛皮癣的口服药物。治疗一个月后，治疗结果见表1
表1治疗组和对照组治疗结果对照表
  治愈 有效 治愈率 有效率
治疗组 124例 149例 72.94% 87.65%
对照组 87例 101例 51.48% 59.76%
治疗组相比对照组具有更高的治愈率和有效率，由此认为，本发明药物治疗牛皮癣具有较好的效果，并且经过一个月的治疗观察，服用本发明药物没有出现任何毒副作用。
具体实施方式
下面结合实施例对本发明作进一步详细说明，但不构成对本发明的任何限制。
    实施例1
按照下述重量准备原材料（kg）：
木香0.8、青皮1.2、麻黄1.6、半夏2.0、石决明1.0和甘草1.4。 
将上述8.0kg中草药放入砂锅中，加入9.0kg的清水，文火煎0.5—1.5小时，反复煎3次后，取出药渣，将药液浓缩成稠膏状，然后加入常规辅料，制成临床接受的散剂，包装后得成品。
实施例2
按照下述重量准备原材料（kg）：
木香0.9、青皮1.2、麻黄1.5、半夏2.0、石决明1.3和甘草1.4。 
将上述8.3kg中草药放入砂锅中，加入9.0kg的清水，文火煎1.5小时，反复煎3次后，取出药渣，将3次药液混合再放入砂锅煎3小时，将药液浓缩成稠膏状，然后将所得的稠膏状药物烘干、研碎、装胶囊，包装后得成品。

Claims (3)

1.一种治疗牛皮癣的药物，其特征在于所述药物是由下述质量比例的原料制成：
        木  香5-13        青  皮10-15
麻  黄8-22       半  夏10-25   
石决明7-20       甘  草6-15。
2.根据权利要求1所述的治疗牛皮癣的药物，其特征在于所述药物是由下述质量比例的原料制成：
        木  香8           青  皮12
麻  黄16          半  夏20   
石决明10          甘  草14。
3.根据权利要求1所述的治疗牛皮癣的药物的制备方法，其特征在于该方法将木香、青皮、麻黄、半夏、石决明和甘草加入60—100重量份的清水，文火煎0.5—1.5小时，反复煎3次后，取出药渣，将3次药液混合放入砂锅煎2—4小时，将药液浓缩成稠膏状，然后加入常规辅料，制成临床接受的药剂。
CN201410531860.8A 2014-10-11 2014-10-11 一种治疗牛皮癣的药物及其制备方法 Pending CN104288399A (zh)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002079748A2 (en) * 2001-02-14 2002-10-10 Bio-Ved Pharmaceuticals, Inc. Withasol and methods of use
CN101274045A (zh) * 2008-04-07 2008-10-01 魏芸 一种外用治疗牛皮癣的药物

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002079748A2 (en) * 2001-02-14 2002-10-10 Bio-Ved Pharmaceuticals, Inc. Withasol and methods of use
CN101274045A (zh) * 2008-04-07 2008-10-01 魏芸 一种外用治疗牛皮癣的药物

Non-Patent Citations (3)

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Title
张玲: "温通玄府治疗银屑病", 《光明中医》 *
王润清等: "《中医外科秘传》", 31 May 1991, 山西科学教育出版社 *
高新彦等: "《古方今用-息风、安神、开窍、消食、驱虫剂》", 29 February 2008, 化学工业出版社 *

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