CN104288299A - Externally-applied traditional Chinese medicinal composition for treating herpes zoster - Google Patents

Externally-applied traditional Chinese medicinal composition for treating herpes zoster Download PDF

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CN104288299A
CN104288299A CN201410506086.5A CN201410506086A CN104288299A CN 104288299 A CN104288299 A CN 104288299A CN 201410506086 A CN201410506086 A CN 201410506086A CN 104288299 A CN104288299 A CN 104288299A
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herpes zoster
chinese medicine
traditional chinese
realgar
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李厚宽
李治宇
李治国
高敏
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704—Polygonum, e.g. knotweed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/28—Mercury; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/36—Arsenic; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/19—Acanthaceae (Acanthus family)
    • A61K36/195—Strobilanthes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • A61K36/315—Isatis, e.g. Dyer's woad
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/32—Burseraceae (Frankincense family)
    • A61K36/324—Boswellia, e.g. frankincense
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/32—Burseraceae (Frankincense family)
    • A61K36/328—Commiphora, e.g. mecca myrrh or balm of Gilead
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/708—Rheum (rhubarb)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/718—Coptis (goldthread)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/756—Phellodendron, e.g. corktree
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
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  • General Health & Medical Sciences (AREA)
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  • Alternative & Traditional Medicine (AREA)
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Abstract

The invention discloses an externally-applied traditional Chinese medicinal composition for treating herpes zoster. The composition is characterized by being prepared by virtue of the following steps: smashing indigo naturalis, coptis chinensis, raw rhubarb, cortex phellodendri, frankincense, myrrh, realgar, calomel and borneol by virtue of a traditional Chinese medicine smasher, pouring sesame oil, uniformly blending to obtain an ointment in pasty form, and bottling for later use. The composition disclosed by the invention is abundant in raw material source and low in cost; and the composition is simple and easy in preparation method, safe, simple and convenient to use, free from any side effect, and obvious in curative effect for treating herpes zoster.

Description

A kind of Chinese medicine external compositions for the treatment of herpes zoster
Art
The present invention relates to a kind of Chinese medicine, relate to a kind of Chinese medicine external compositions for the treatment of herpes zoster or rather.
Technical background
Herpes zoster is the acute skin mucosa infection disease caused by varicella zoster virus.Belong to the traditional Chinese medical science " herpes zoster ", " herpes zoster ", " herpes zoster " category.Clinically with occur suddenly, along the herpes of neural zonal distribution, one-sided distribution, dense clusters for feature, pain is obvious.Herpes zoster increased with the age, and symptom also increases the weight of, and the course of disease extends.Some patient is after herpes healing, and still have neuropathic pain conditions periods of months or longer time, sickness rate is high clinically, and doctor trained in Western medicine mostly is antiviral, immunostimulant, antibacterial, antiinflammatory, analgesia therapy, but produces little effect.I excavates motherland's traditional medicine treasure-house with great concentration, scientific composition, and practice principle for many years, respond well.
Summary of the invention
Of the present inventionly be that overcoming the deficiencies in the prior art provides a kind of Chinese medicine external compositions for the treatment of herpes zoster at present, raw material sources are convenient, and processing is simple.
Chinese medicine composition of the present invention, is characterized in that counting by weight, is made up of following raw materials according:
Indigo Naturalis 8-12 part, Rhizoma Coptidis 8-12 part, Radix Et Rhizoma Rhei 8-12 part, Cortex Phellodendri 8-12 part, Olibanum 4-8 part, Myrrha 4-8 part, Realgar 4-6 part, Calomelas 1-3 part, Borneolum Syntheticum 4-6 part, Oleum Sesami 98-102 part.
In a specific embodiment, by weight, the consumption of various raw material is:
Indigo Naturalis 10 parts, Rhizoma Coptidis 10 parts, Radix Et Rhizoma Rhei 10 parts, Cortex Phellodendri 10 parts, Olibanum 6 parts, Myrrha 6 parts, Realgar 5 parts, Calomelas 2 parts, Borneolum Syntheticum 5 parts, 100 parts, Oleum Sesami.
The drug action mechanism of each Chinese medicine:
Indigo Naturalis: salty, cold.Return Liver Channel.Energy heat-clearing and toxic substances removing, removing heat from blood, arresting convulsion.
Rhizoma Coptidis: bitter cold.GUIXIN, spleen, kidney, gallbladder, large intestine channel.Effect: heat clearing and damp drying, eliminating fire and detoxication.
Radix Et Rhizoma Rhei: bitter in the mouth, cold in nature.Return stomach, spleen, large intestine, liver, pericardium channel.Effect: heat clearing and damp drying, eliminating fire and detoxication.
Cortex Phellodendri: meridian distribution of property and flavor: bitter, cold.Return kidney, bladder, large intestine channel.Effect: heat clearing and damp drying, eliminating fire and detoxication, dehumidifying of bringing down a fever.
Olibanum: acrid in the mouth, hardship, tepor.GUIXIN, liver, spleen.Effect: blood-activating and qi-promoting, inducing menstruation to relieve menalgia, detumescence and promoting granulation.
Myrrha: bitter, pungent, flat.Enter the heart, Liver Channel.Effect: loose blood blood stasis removing, subduing swelling and relieving pain.
Realgar: warm in nature, acrid in the mouth, bitter in the mouth.Enter heart channel, Liver Channel, stomach warp.Effect: heat-clearing and toxic substances removing, blood stasis dispersing and deswelling
Borneolum Syntheticum: pungent, bitter, is slightly cold.GUIXIN, spleen, lung meridian.Logical all keys, effect: loose stagnated fire, removing nebula improving eyesight, reducing swelling and alleviating pain.
Calomelas: fiber crops are pungent, cold, poisonous.Enter liver, kidney channel.External parasite killing counteracting toxic substances, except bromhidrosis.
Oleum Sesami: sweet in the mouth, cold nature is nontoxic.Effect: moistening dryness for relaxing bowels, removing toxic substances, granulation promoting.
The pathogenesis of herpes zoster:
The traditional Chinese medical science is thought: belong to feelings will internal injury, depression of liver-QI more, lights a fire for a long time, the excessive skin of fire-toxin; Or damp and hot temperature knot, ties in skin, or tired infection poison is evil, and coagulation of QI-blood makes so in skin.
Fang Xie:
Because the cause of disease is fire-toxin, damp and hot, so with Indigo Naturalis heat-clearing and toxic substances removing, removing heat from blood, Rhizoma Coptidis, Radix Et Rhizoma Rhei heat clearing and damp drying, eliminating fire and detoxication, Cortex Phellodendri heat clearing and damp drying, eliminating fire and detoxication, dehumidifying of bringing down a fever, four medicines share the effect of heat clearing away, pathogenic fire purging, removing toxic substances of gathering altogether.Olibanum, Myrrha blood-activating and qi-promoting, inducing menstruation to relieve menalgia, detumescence and promoting granulation.Realgar, Borneolum Syntheticum heat-clearing and toxic substances removing, blood stasis dispersing and deswelling, loose stagnated fire.Calomelas counteracting toxic substances sore, modern medicine study has good broad-spectrum antibacterial effect, all has good fungistatic effect to multiple Gram-positive and negative bacterium and pathogenic dermatophytes.Oleum Sesami has awakening consciousness, replenishing vital essence and blood, physical strength profiting, longue meat, the merit of profit skin.
Manufacture method:
First Indigo Naturalis, Rhizoma Coptidis, Radix Et Rhizoma Rhei, Cortex Phellodendri, Olibanum, Myrrha, Realgar, Calomelas, the broken medicine machine of Borneolum Syntheticum Chinese medicine are smashed to pieces, then pour Oleum Sesami into and mix well into pasty state ointment, bottling can be for subsequent use.
Administrated method:
By herpes zoster region povidone iodine routine disinfection during treatment, seven-star needle's pricking method is used in local, with little petechia for degree, or carries out quick block pricking method with three edged needle in herpes central authorities.Then be coated with directly outer for this ointment, 1-2 time on the one.
Points for attention: during medication, ban on opium-smoking and the opium trade wine, pungent savoury.Face contraindication in acupuncture, in case affect attractive in appearance, directly outer painting, symptom the lighter, also can be coated with directly outward.
Beneficial effect: as shown from the above technical solution, abundant raw material source of the present invention, with low cost.Manufacture method is simple, and use safety is simple and easy to do, without any side effects, is used for the treatment of Herpes Zoster obvious.
Efficacy assessment standard:
Cure: Schultz-Charlton or leave pigmented spots in a week, but pain disappearance; Effective: deflorescence or all form a scab in a week, pain obviously alleviates; Invalid: in one week, erythra does not disappear or has new erythra to occur, pain does not alleviate.
Clinical effectiveness:
Year June in January, 2009 to 2014, in the routine patient of clinical statistics 670, man 370 example, female 300 example; The course of disease is the longest 5 days, the shortest 1 day, the oldest 82 years old, minimum 8 years old; Wherein 30 examples come across face, and all the other are all published on lower back and extremity.For without the infected, in one week, cure rate is 92%, concurrent infection person recovery from illness in the longest 10 days.Above-mentioned therapy is adopted only to have 17 routine neuralgia sequela, by anti symptom treatment about 20 days recovery from illness.
Detailed description of the invention
Embodiment
First Indigo Naturalis 10 parts, Rhizoma Coptidis 10 parts, Radix Et Rhizoma Rhei 10 parts, Cortex Phellodendri 10 parts, Olibanum 6 parts, Myrrha 6 parts, Realgar 4-6 part, Calomelas 2 parts, the Borneolum Syntheticum 5 parts broken medicine machine of Chinese medicine are smashed to pieces, then pour 100 parts, Oleum Sesami into and mix well, obtain ointment, can be for subsequent use.
By herpes zoster region povidone iodine routine disinfection during treatment, seven-star needle's pricking method is used in local, with little petechia for degree, or carries out quick block pricking method with three edged needle in herpes central authorities.Then be coated with directly outer for this ointment, 1-2 time on the one.
Model case
1: model so-and-so, man, 42 years old, live city, Huaibei City Vancouver community resident.Suffer from herpes zoster on the left of patient one week, affected part color of the leather purple, herpes cluster, hurt like hell, night increases the weight of, vexed, bitter taste, and poor appetite is hard and dry, yellow urine, red tongue, yellowish fur, pulse condition flood number.I am at herpes zoster region povidone iodine routine disinfection, and the quick pricking method petechia of seven-star needle, local, art finishes, then uses iodophor disinfection, and 75% ethanol takes off iodine, then uses the ointment exterior coating treatment described in above-described embodiment, once-a-day.Further consultation after 3 days, clinical symptoms obviously alleviates, and infiltrates without diffusion, and spirit takes a turn for the better, and appetite increases, a line on the one of defecating.Without special untoward reaction after medication.Patient is enjoined to continue outer wiping until color of the leather disappears, smooth recovery from illness.Follow up a case by regular visits to after first quarter moon and do not recur again.
2: Zhang, female, 70 years old, live light fixture city, south, the Asian Games Village, Suixi County, left chest and back painful skin lesion was gone to a doctor for one week.With agitation, xerostomia, yellow urine, red tongue with thin and yellow fur, stringy and rolling pulse, doctor trained in Western medicine gives antiviral and vitamin medicaments treatment, without being clearly better.Give routine disinfection, with three edged needle after herpes central authorities carry out quick block pricking method, feel local pain after the ointment described in external above-described embodiment immediately and alleviate, continuous 7 day every day 1 time, after 7 days skin lesion dry and hard, disappear, then use 7 days, be completely recovered for totally 14 times.

Claims (3)

1. treat a Chinese medicine external compositions for herpes zoster, it is characterized in that counting by weight, be made up of following raw materials according:
Indigo Naturalis 8-12 part, Rhizoma Coptidis 8-12 part, Radix Et Rhizoma Rhei 8-12 part, Cortex Phellodendri 8-12 part, Olibanum 4-8 part, Myrrha 4-8 part, Realgar 4-6 part, Calomelas 1-3 part, Borneolum Syntheticum 4-6 part, Oleum Sesami 98-102 part.
2. a kind of Chinese medicine external compositions for the treatment of herpes zoster as claimed in claim 1, it is characterized in that: count by weight, the consumption of various raw material is: Indigo Naturalis 10 parts, Rhizoma Coptidis 10 parts, Radix Et Rhizoma Rhei 10 parts, Cortex Phellodendri 10 parts, Olibanum 6 parts, Myrrha 6 parts, Realgar 5 parts, Calomelas 2 parts, Borneolum Syntheticum 5 parts, 100 parts, Oleum Sesami.
3. treat the preparation method of the Chinese medicine external compositions of herpes zoster for one kind, according to following steps: first Indigo Naturalis, Rhizoma Coptidis, Radix Et Rhizoma Rhei, Cortex Phellodendri, Olibanum, Myrrha, Realgar, Calomelas, the broken medicine machine of Borneolum Syntheticum Chinese medicine are smashed to pieces, then pour Oleum Sesami into and mix well into pasty state ointment.
CN201410506086.5A 2014-09-17 2014-09-17 Externally-applied traditional Chinese medicinal composition for treating herpes zoster Pending CN104288299A (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105748989A (en) * 2016-03-14 2016-07-13 赵剑锋 Anti-bacterial and anti-virus composition and preparation method thereof
CN108186810A (en) * 2018-01-19 2018-06-22 范鹏程 A kind of Chinese medicine preparation for being used to treat herpes zoster
CN112402508A (en) * 2020-12-14 2021-02-26 翁德麟 Traditional Chinese medicine composition for treating herpes zoster and preparation method thereof
CN112741870A (en) * 2021-01-26 2021-05-04 邓羽 External ointment for treating herpes zoster and preparation method thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101474281A (en) * 2009-01-20 2009-07-08 袁崇芬 Pain-eliminating paste for zoster and preparation method thereof
CN101822737A (en) * 2009-03-05 2010-09-08 朱运喜 Traditional Chinese medicine composition for externally treating herpes zoster and preparation method thereof
CN102038853A (en) * 2009-10-20 2011-05-04 焦趁英 Externally applied plaster for treating herpes zoster

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101474281A (en) * 2009-01-20 2009-07-08 袁崇芬 Pain-eliminating paste for zoster and preparation method thereof
CN101822737A (en) * 2009-03-05 2010-09-08 朱运喜 Traditional Chinese medicine composition for externally treating herpes zoster and preparation method thereof
CN102038853A (en) * 2009-10-20 2011-05-04 焦趁英 Externally applied plaster for treating herpes zoster

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105748989A (en) * 2016-03-14 2016-07-13 赵剑锋 Anti-bacterial and anti-virus composition and preparation method thereof
CN105748989B (en) * 2016-03-14 2020-03-10 赵剑锋 Antibacterial and antiviral composition and preparation method thereof
CN108186810A (en) * 2018-01-19 2018-06-22 范鹏程 A kind of Chinese medicine preparation for being used to treat herpes zoster
CN112402508A (en) * 2020-12-14 2021-02-26 翁德麟 Traditional Chinese medicine composition for treating herpes zoster and preparation method thereof
CN112741870A (en) * 2021-01-26 2021-05-04 邓羽 External ointment for treating herpes zoster and preparation method thereof

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Application publication date: 20150121