CN104274789A - Traditional Chinese medicine composition for treating depression - Google Patents
Traditional Chinese medicine composition for treating depression Download PDFInfo
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- CN104274789A CN104274789A CN201410630614.8A CN201410630614A CN104274789A CN 104274789 A CN104274789 A CN 104274789A CN 201410630614 A CN201410630614 A CN 201410630614A CN 104274789 A CN104274789 A CN 104274789A
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Abstract
The invention belongs to the field of pharmaceutical preparations and in particular relates to a traditional Chinese medicine composition for treating depression. The traditional Chinese medicine composition is prepared from the following raw materials: bighead atractylodes rhizome, Korean pine seed, angelica sinensis, Chinese yam, inula flower root, uncaria, rhizoma cyperi, red rhodobryum, day lily, medicated leaven, radix polygonati officinalis, scutellaria baicalensis, fructus forsythiae, mangnolia officinalis, centella, jasmine, spina date seed, acanthopanax, rhodiola rosea, dandelion, radix bupleuri, Ligusticum wallichii, semen cassiae, herba epimedii, immature bitter orange, mulberry fruit and radix curcumae. The traditional Chinese medicine composition is prepared into capsules, tablets, granules and other dosage forms according to the general pharmaceutical method. The pharmaceutical preparation disclosed by the invention treats both symptoms and root causes of the depression, does not have any side effect and is low in price, easy and convenient to prepare and wide in application prospect.
Description
Technical field
The invention belongs to technical field of Chinese medicines, concrete, relate to and a kind ofly treat depressed Chinese medicine composition and preparation method thereof.
Background technology
Depression or depressive disorder are global main spirits hygienic issues, its cause of disease is very complicated, so far illustrate not yet completely, increasingly aggravate along with modern society strives unexpectedly, the mental pressure of people constantly increases, feelings will disease becomes the principal disease in the present age, and World Health Organization (WHO) points out that the maximum disease that 21st century people face is mental sickness.WHO estimates, depressive illness person is suffered from the whole world 1.2 hundred million to 2 hundred million people.1996, the investigation about " Disease Spectrum " that WHO announces showed: due to illness to cause disability (functional impairment) to add up, depression accounts for second, account for that whole disease always bears 6.2%.This kind of patient is depressed, and slowly, speech action reduces, and inner experience is very painful, often has thoughts of suicide and suicide in association, and external only depression Mortality of suicide is just up to 15% according to reports.Depression lifetime prevalence is 6.1-9.5%, and the people of about 13-20% once had once or once above depressed experience all one's life.Along with development, the rhythm of life quickening of society, depression, in increasing year by year, is estimated after 25 years, will be accounted for disease and always bear about 10%.
At present, the chemicals of Cure of depression mainly contains in the world, and three ring antidepressants (TCAS), as nortriptyline and desmethylimipramine etc., oxidase inhibitor (MAOLS), as phenelzine, tranylcypromine and isocarbossazide etc., selectivity 5-HT reuptake inhibitor (SSRLS), as fluoxetine, Clovoxamine, Sertraline etc., another kind is lithium preparation, and lithium is used for treating manic depression, and some major depression often recurred.These chemicalses often cause many untoward reaction, as calmness, insomnia, postural hypotension, urine retention, Nausea and vomiting and interact with food.
Motherland's medical science thinks that melancholia is because feelings will is not relaxed, the class disease caused by depression and stagnation of QI.Main manifestations for feeling depressed, irritable emotion, distending pain over the hypochondrium, or irritability is kind cries, and blocking if any foreign body in pharynx, the various complicated symptoms such as insomnia.Its normal manner, then depression and stagnation of QI are lost in the fluctuation of feelings will, and with the passing of time the stagnation of QI does not heal, and by gas and blood, become raw multiterminal, can cause multiple symptom, therefore have saying of " six kinds of stagnation-syndromes ".Namely the stagnation of QI, blood stagnation, phlegm stagnancy, damp-stagnancy, heat stagnation, food stagnancy etc. six kinds, are wherein elder generation with the stagnation of QI, and then wet, expectorant, heat, blood, food etc. are all strongly fragrantly could be formed.
The generation of melancholia is because feelings will hindered, depression of liver-QI, causes gradually caused by the five internal organs mechanism of qi discord.But mainly liver, spleen, the heart three are dirty gets involved and disorder of QI and blood forms:
(1) disgruntled not smooth, make liver lose bar and reach, gas loses catharsis, and causes depression of liver-QI.The stagnation of QI with the passing of time can fire-transformation, and the stagnation of QI can cause again blood stasis not all right.If stagnation of liver-QI and spleen, or ponder over puzzled, overstrain impairing the spleen, all can make dysfunction of the spleen in transportation, accumulate humidogene expectorant, cause stagnation of QI phlegm stagnancy.If turbid damp stops, or dyspepsia does not disappear, or phlegm-damp heat-transformation, then can develop into the cards such as damp-stagnancy, food stagnancy, heat stagnation.
(2) feelings will is unsuccessful, and stagnation of liver-QI presses down spleen, and consume sad gas, nutrient blood gradually consumes, and the heart is become homeless foster, and god becomes homeless Tibetan, and namely so-called melancholy is overtaxed one's nerves, and can cause irritability.If chronic depression impairing the spleen, diet reduces, biochemical weary source, then insufficiency of vital energy and blood, deficiency of both the heart and spleen, and the easy impairment of YIN blood of strongly fragrant fire-transformation of a specified duration, involves in kidney, hyperactivity of fire caused by deficiency of YIN, and development can become all deficient times thus.
Melancholia because of disgruntled, ponder over, institute that is grieved, worried seven emotions hinders, cause the liver failing to maintain the normal flow of QI, spleen mistake transporting, the mind is not normal, and internal organs yin and yang qi and blood disorder forms.The first cause of disease stagnation of QI and hold damp-phlegm, food stagnation, heat stagnation person under the arm, then mostly empirical; Prolonged illness is by gas and blood, and Sthenia is transforming into asthenia, and overtax one's nerves as strongly fragrant for a long time, heart spleen all loses, and hyperactivity of fire caused by deficiency of YIN etc. all belong to deficiency syndrome.
The object of this invention is to provide that a kind for the treatment of both the principal and secondary aspects of a disease, side effect are little, safe ready, cheap Chinese medicine composition.Its objective is to solve treatment depressed, overcome Western medicine toxic and side effects large, easily repeatedly, the inapparent problem of therapeutic effect, reaches the object for the treatment of both the principal and secondary aspects of a disease in drug withdrawal.
Summary of the invention
The defect that present inventor exists based on the medicine of existing Cure of depression, by the research to Chinese medicine, and in conjunction with dialectical demonstration, in many ways the length of many families is collected, seek therapeutic regimen, from motherland's medical treasure-house, filter out tranquilizing the mind, the natural Chinese medicine of tonify deficiency righting, by theory of Chinese medical science prescription, skim the cream off milk, it is made to play to clear away heart-fire place tired, YIN nourishing and the production of body fluid promoting, to calm the nerves the effect nourished heart, adopt natural Chinese medicines raw material, through systematic study, scientific compatibility, the Chinese medicine composition for depression of the present invention is meticulously mixed with in conjunction with Traditional Chinese Medicine technology, depression is had to effect of rapid healing.
For achieving the above object, the technical solution used in the present invention is as follows:
A Chinese medicine composition for orally taken for curing depression, is characterized in that it is prepared by following raw material and obtains:
Rhizoma Atractylodis Macrocephalae 30-40 part, Semen pini koraiensis 30-40 part, Radix Angelicae Sinensis 30-40 part, Rhizoma Dioscoreae 30-40 part,
Radix Inulae 28-30 part, Ramulus Uncariae Cum Uncis 28-30 part, Rhizoma Cyperi 28-30 part, Rhodobryum roseum Limpr. 25-30 part,
Radix hemerocalis plicatae 25-30 part, Massa Medicata Fermentata 25-30 part, Rhizoma Polygonati Odorati 20-25 part, Radix Scutellariae 20-25 part,
Fructus Forsythiae 20-25 part, Cortex Magnoliae Officinalis 18-20 part, Herba Centellae 18-20 part, Fructus Gardeniae 18-20 part,
Semen Ziziphi Spinosae 15-20 part, Radix Et Caulis Acanthopanacis Senticosi 15-20 part, Radix Rhodiolae 15-20 part, Herba Taraxaci 15-20 part,
Radix Bupleuri 10-15 part, Rhizoma Chuanxiong 10-15 part, Semen Cassiae 10-15 part, Herba Epimedii 10-15 part,
Fructus Aurantii Immaturus 8-10 part, Fructus Mori 7-9 part, Radix Curcumae 5-8 part.
Preferably: a kind of Chinese medicine composition of orally taken for curing depression, it is characterized in that it is prepared by following weight proportioning raw material and obtains,
The Rhizoma Atractylodis Macrocephalae 30 parts, Semen pini koraiensis 30 parts, Radix Angelicae Sinensis 30 parts, Rhizoma Dioscoreae 30 parts,
Radix Inulae 28 parts, Ramulus Uncariae Cum Uncis 28 parts, Rhizoma Cyperi 28 parts, Rhodobryum roseum Limpr. 25 parts,
Radix hemerocalis plicatae 25 parts, Massa Medicata Fermentata 25 parts, Rhizoma Polygonati Odorati 20 parts, Radix Scutellariae 20 parts,
Fructus Forsythiae 20 parts, Cortex Magnoliae Officinalis 18 parts, Herba Centellae 18 parts, Fructus Gardeniae 18 parts,
Semen Ziziphi Spinosae 15 parts, Radix Et Caulis Acanthopanacis Senticosi 15 parts, Radix Rhodiolae 15 parts, Herba Taraxaci 15 parts,
Radix Bupleuri 10 parts, Rhizoma Chuanxiong 10 parts, Semen Cassiae 10 parts, Herba Epimedii 10 parts,
Fructus Aurantii Immaturus 8 parts, Fructus Mori 7 parts, Radix Curcumae 5 parts.
Medicine of the present invention can add one or more pharmaceutically acceptable carriers and be mixed and made into any one clinically or pharmaceutically acceptable dosage form, preferred oral preparation.When being applied in the mode of oral administration the patient needing this treatment, conventional solid preparation can be made into, as tablet, capsule, soft capsule etc.
Preferably, its preparation method is:
(1) get the Rhizoma Atractylodis Macrocephalae, Semen pini koraiensis, Radix Angelicae Sinensis, Rhizoma Dioscoreae, Radix Inulae, Ramulus Uncariae Cum Uncis, Herba Centellae, Fructus Gardeniae, Semen Ziziphi Spinosae, Radix Et Caulis Acanthopanacis Senticosi, Radix Rhodiolae, Herba Taraxaci, Radix Bupleuri, Rhizoma Chuanxiong mix in described ratio, add the ethanol relative to mixture 8 times amount 95%, reflux, extract, 3 times, each 2 hours, extracting solution merges, and is concentrated into the clear paste that density is 1.25g/ml, 80 DEG C of oven dry, be ground into powder, be complex A;
(2) get surplus stock medicine and Rhizoma Cyperi, Rhodobryum roseum Limpr., Radix hemerocalis plicatae, Massa Medicata Fermentata, Rhizoma Polygonati Odorati, Radix Scutellariae, Fructus Forsythiae, Cortex Magnoliae Officinalis, Semen Cassiae, Herba Epimedii, Fructus Aurantii Immaturus, Fructus Mori, Radix Curcumae add 5 times of soak by water twice, 2 hours first times, second time 1 hour, merge twice decoction liquor, it is the extractum of 1.25g/ml that drying under reduced pressure obtains density, after 80 DEG C of oven dry, be ground into powder, be complex B;
(3) by complex A and complex B mixing and stirring, sterilization obtains capsule product.
Chinese medicine mind tranquilizing and the heart calming of the present invention, reinforcing the heart of nourishing blood, tranquilizing the mind, waking up the patient from unconsciousness by clearing away phlegm nourishing the liver and kidney, have definite curative effect to depression, side effect is little.Fill blood, nourish heart kidney.
Usage and dosage: oral, a 0.5g, three times on the one.
Attention: hyperpietic avoids clothes, warm water delivery service.Period in a medicine avoids pungent food and cold and cool food, and avoid emotional stimulation, life is regular.
The present invention is used for depressed Chinese patent medicine excellent results and is:
1. the present invention is used for depressed Chinese medicine preparation compatibility and meets Chinese medicine " monarch " principle, be made up of pure Chinese medicine, each component meets pharmaceutical control law regulation, utilize the comprehensive function of each taste Chinese medicine, not containing chemical components, not containing hormone, have no side effect, treating both the exterior and interior, reaches better enriching yin and nourishing kidney, tranquilizing by nourishing the heart effect;
2. this medicament short treating period, total effective rate is high, not easily recurs more.
3. technique of the present invention is simple, reduces production cost, alleviates the financial burden of patient.
Detailed description of the invention
Embodiment 1
Treat a depressed Chinese medicine composition, it is characterized in that it is prepared by following weight proportioning raw material and obtains,
The Rhizoma Atractylodis Macrocephalae 30 parts, Semen pini koraiensis 30 parts, Radix Angelicae Sinensis 30 parts, Rhizoma Dioscoreae 30 parts,
Radix Inulae 28 parts, Ramulus Uncariae Cum Uncis 28 parts, Rhizoma Cyperi 28 parts, Rhodobryum roseum Limpr. 25 parts,
Radix hemerocalis plicatae 25 parts, Massa Medicata Fermentata 25 parts, Rhizoma Polygonati Odorati 20 parts, Radix Scutellariae 20 parts,
Fructus Forsythiae 20 parts, Cortex Magnoliae Officinalis 18 parts, Herba Centellae 18 parts, Fructus Gardeniae 18 parts,
Semen Ziziphi Spinosae 15 parts, Radix Et Caulis Acanthopanacis Senticosi 15 parts, Radix Rhodiolae 15 parts, Herba Taraxaci 15 parts,
Radix Bupleuri 10 parts, Rhizoma Chuanxiong 10 parts, Semen Cassiae 10 parts, Herba Epimedii 10 parts,
Fructus Aurantii Immaturus 8 parts, Fructus Mori 7 parts, Radix Curcumae 5 parts.
Its preparation method is:
(1) get the Rhizoma Atractylodis Macrocephalae, Semen pini koraiensis, Radix Angelicae Sinensis, Rhizoma Dioscoreae, Radix Inulae, Ramulus Uncariae Cum Uncis, Herba Centellae, Fructus Gardeniae, Semen Ziziphi Spinosae, Radix Et Caulis Acanthopanacis Senticosi, Radix Rhodiolae, Herba Taraxaci, Radix Bupleuri, Rhizoma Chuanxiong mix in described ratio, add the ethanol relative to mixture 8 times amount 95%, reflux, extract, 3 times, each 2 hours, extracting solution merges, and is concentrated into the clear paste that density is 1.25g/ml, 80 DEG C of oven dry, be ground into powder, be complex A;
(2) get surplus stock medicine and Rhizoma Cyperi, Rhodobryum roseum Limpr., Radix hemerocalis plicatae, Massa Medicata Fermentata, Rhizoma Polygonati Odorati, Radix Scutellariae, Fructus Forsythiae, Cortex Magnoliae Officinalis, Semen Cassiae, Herba Epimedii, Fructus Aurantii Immaturus, Fructus Mori, Radix Curcumae add 5 times of soak by water twice, 2 hours first times, second time 1 hour, merge twice decoction liquor, it is the extractum of 1.25g/ml that drying under reduced pressure obtains density, after 80 DEG C of oven dry, be ground into powder, be complex B;
(3) by complex A and complex B mixing and stirring, sterilization obtains capsule product.
Chinese medicine mind tranquilizing and the heart calming of the present invention, reinforcing the heart of nourishing blood, tranquilizing the mind, waking up the patient from unconsciousness by clearing away phlegm nourishing the liver and kidney, have definite curative effect to depression, side effect is little.Fill blood, nourish heart kidney.
Usage and dosage: oral, a 0.5g, three times on the one.
Embodiment 2
Treat a depressed Chinese medicine composition, it is characterized in that it is prepared by following raw material and obtains:
The Rhizoma Atractylodis Macrocephalae 40 parts, Semen pini koraiensis 40 parts, Radix Angelicae Sinensis 40 parts, Rhizoma Dioscoreae 40 parts,
Radix Inulae 30 parts, Ramulus Uncariae Cum Uncis 30 parts, Rhizoma Cyperi 30 parts, Rhodobryum roseum Limpr. 30 parts,
Radix hemerocalis plicatae 30 parts, Massa Medicata Fermentata 30 parts, Rhizoma Polygonati Odorati 25 parts, Radix Scutellariae 25 parts,
Fructus Forsythiae 25 parts, Cortex Magnoliae Officinalis 20 parts, Herba Centellae 20 parts, Fructus Gardeniae 20 parts,
Semen Ziziphi Spinosae 20 parts, Radix Et Caulis Acanthopanacis Senticosi 20 parts, Radix Rhodiolae 20 parts, Herba Taraxaci 20 parts,
Radix Bupleuri 15 parts, Rhizoma Chuanxiong 15 parts, Semen Cassiae 15 parts, Herba Epimedii 15 parts,
Fructus Aurantii Immaturus 10 parts, Fructus Mori 9 parts, Radix Curcumae 8 parts.
Its preparation method is:
(1) get the Rhizoma Atractylodis Macrocephalae, Semen pini koraiensis, Radix Angelicae Sinensis, Rhizoma Dioscoreae, Radix Inulae, Ramulus Uncariae Cum Uncis, Herba Centellae, Fructus Gardeniae, Semen Ziziphi Spinosae, Radix Et Caulis Acanthopanacis Senticosi, Radix Rhodiolae, Herba Taraxaci, Radix Bupleuri, Rhizoma Chuanxiong mix in described ratio, add the ethanol relative to mixture 8 times amount 95%, reflux, extract, 3 times, each 2 hours, extracting solution merges, and is concentrated into the clear paste that density is 1.25g/ml, 80 DEG C of oven dry, be ground into powder, be complex A;
(2) get surplus stock medicine and Rhizoma Cyperi, Rhodobryum roseum Limpr., Radix hemerocalis plicatae, Massa Medicata Fermentata, Rhizoma Polygonati Odorati, Radix Scutellariae, Fructus Forsythiae, Cortex Magnoliae Officinalis, Semen Cassiae, Herba Epimedii, Fructus Aurantii Immaturus, Fructus Mori, Radix Curcumae add 5 times of soak by water twice, 2 hours first times, second time 1 hour, merge twice decoction liquor, it is the extractum of 1.25g/ml that drying under reduced pressure obtains density, after 80 DEG C of oven dry, be ground into powder, be complex B;
(3) by complex A and complex B mixing and stirring, sterilization obtains capsule product.
Chinese medicine mind tranquilizing and the heart calming of the present invention, reinforcing the heart of nourishing blood, tranquilizing the mind, waking up the patient from unconsciousness by clearing away phlegm nourishing the liver and kidney, have definite curative effect to depression, side effect is little.Fill blood, nourish heart kidney.
Usage and dosage: oral, a 0.5g, three times on the one 30 days is a course for the treatment of.
Embodiment 3
Acute toxicity testing: application mice 60, male and female half and half, body weight 30 ~ 40g, carries out acute toxicity test.Mice is divided into three groups at random, i.e. matched group and administration group one group, administration two groups, often organize 20, fasting 12 hours before experiment, the Chinese patent medicine that administration 1 group gives embodiments of the invention 1 preparation is dissolved in gastric infusion in water (gavage unit dosage form is 50g crude drug/kg), administration 2 groups gives Chinese patent medicine prepared by the embodiment of the present invention 2, matched group gives normal saline, administration in one day 2 times, delivery time 6 hours, Continuous Observation 14 days after administration, and record mice toxic reaction and death toll.Experimental result shows: compare with matched group, and after administration, mice has no notable difference, and experiment Continuous Observation 14 days, mouse systemic situation, diet, drinking-water, body weight increase all normal.Therefore Chinese patent medicine acute toxicity of the present invention is extremely low, clinical drug safety.
Long term toxicity test: respectively by Chinese medicine embodiment 1 of the present invention, embodiment 2 capsule to mice continuous use 15 weeks and drug withdrawal after 3 weeks, result shows: the index such as hair, behavior, defecation, body weight, organ weights, hemogram, hepatic and renal function, blood glucose, blood fat of Chinese medicine of the present invention to mice all has no significant effect, internal organs naked eyes do not find that difference change and histological indications show, medication 15 weeks and drug withdrawal are after 3 weeks, and Organs of Mice is all without obviously changing.Illustrate that Chinese medicine of the present invention is little to toxicity after mice long-term prescription, also there is no difference reaction after drug withdrawal, application safety.
Embodiment 4
1, clinical data
98 routine clinical patients chosen by clinical data, are divided into two groups at random: treatment group 50 example, wherein man 28 example, female 22 example, 17 ~ 71 years old age, the course of disease 1 year ~ 3 years, and Hamilton depressive scale is marked: 24.3 ± 2.5 points; Matched group 48 example, wherein man 25 example, female 23 example, age 18-69 year, the course of disease 1 year ~ 3 years, Hamilton depressive scale mark: 23.9 ± 2.3 points; Two groups of Genders, age, the course of disease, Hamilton depressive scale scoring data, through statistical procedures, without significant difference (P > 0.05), have comparability.
Case selected condition (1) is diagnosed as the patient of depression according to the diagnostic criteria [2] of " Chinese Spirit classification of diseases and diagnostic criteria " the 3rd edition (CCMD-3); (2) vital sign is steady, and sanity, can understand depression scale content, has certain ability to express, energy partner treatment person; The person that do not take antidepressant drug in (3) 2 weeks; (4) differential diagnosis in tcm belongs to hepatic and renal YIN deficiency person.(disease is seen: be in a very depressed state and/or hebetude, insomnia and dreamful sleep, soreness of the waist and knees, dysphoria with feverish sensation in the chest palms and soles, dizziness and tinnitus, red tongue with thin fur, thready pulse etc.).
Therapeutic Method
Treatment group gives Chinese medicine composition prepared by the embodiment of the present invention 1, and matched group is with fluoxetine (Lilly pharmaceutical Co. Ltd produces, and trade name is fluoxetine, every 20mg) initial amount 20mg/d.6 weeks courses for the treatment of.Psychological counseling and necessary humanistic care has all been carried out, other adjuvant drugs of stopping using during two groups of patient assessment.
The evaluation of curative effect
Criterion of therapeutical effect is before treatment and treat 1,2,4,6 week, and employing Hamilton depressive scale, Clinical Global Impression (CGI) evaluate curative effect.Within 1,2,4,6 weeks, untoward reaction is evaluated with sub-anti-symmetrical matrix (TESS) in treatment.
Lab testing: in treat before and the 6th week time carry out the inspections such as blood, routine urinalysis, electrocardiogram, Liver and kidney function, in treat before and treat at the end of measure weight.Kappa value is 0.75-0.88, HAMD deduction rate >=75% is recovery from illness, and 50-74% is marked improvement, and 25-49% is for progressive, and < 25% is invalid.
Before and after two groups of treatments, depression scale scoring is compared
| Group | Example time | Recovery from illness | Effective | Effectively | Invalid | Total effective rate (%) |
| Treatment group | 50 | 21 | 13 | 11 | 5 | 90 |
| Matched group | 48 | 10 | 19 | 7 | 12 | 75 |
As seen from the above table: cure rate and the total effective rate for the treatment of group are all obviously better than matched group, have significant difference.
Embodiment 5
Exemplary embodiments
Cao, female, 51 years old, disease played the several years, once in mental hospital and the diagnosis and treatment repeatedly of all side table large hospitals.Recent aggravation, often with knitted brows, again and again sigh, eyes close, and eyelid blinks and makes a movement all very difficult, and two arms are unable, and two legs is walked with difficulty, and sleep maintains by sleeping pill, bradyphrenia.Desire of seeking medical advice is strong, and body of the tongue is scarlet, and wiry and frequent pulse is strong.Give pharmaceutical preparation prepared by embodiment 1, coordinate psychological counseling, after treating 3 courses for the treatment of, health returns to one's perfect health, current being in a good state of health of patient.
Above-mentioned each Chinese medicinal components that the present invention adopts makes compatibility mutually, its collaborative effect of curing the disease can be played, there is between each composition of raw material of Chinese medicine used drug effect be interweaved and mutually promote and coordinate usefulness, through clinical verification, have good therapeutic effect to depression, in the applicant's medical practice for many years, the case Numerous of curing, all obtains good effect, and with low cost, alleviate the burden of patient, have broad application prospects.
Claims (3)
1. treat a depressed Chinese medicine composition, it is characterized in that, described Chinese medicine composition is prepared by the raw material of following weight parts and obtains:
Rhizoma Atractylodis Macrocephalae 30-40 part, Semen pini koraiensis 30-40 part, Radix Angelicae Sinensis 30-40 part, Rhizoma Dioscoreae 30-40 part,
Radix Inulae 28-30 part, Ramulus Uncariae Cum Uncis 28-30 part, Rhizoma Cyperi 28-30 part, Rhodobryum roseum Limpr. 25-30 part,
Radix hemerocalis plicatae 25-30 part, Massa Medicata Fermentata 25-30 part, Rhizoma Polygonati Odorati 20-25 part, Radix Scutellariae 20-25 part,
Fructus Forsythiae 20-25 part, Cortex Magnoliae Officinalis 18-20 part, Herba Centellae 18-20 part, Fructus Gardeniae 18-20 part,
Semen Ziziphi Spinosae 15-20 part, Radix Et Caulis Acanthopanacis Senticosi 15-20 part, Radix Rhodiolae 15-20 part, Herba Taraxaci 15-20 part,
Radix Bupleuri 10-15 part, Rhizoma Chuanxiong 10-15 part, Semen Cassiae 10-15 part, Herba Epimedii 10-15 part,
Fructus Aurantii Immaturus 8-10 part, Fructus Mori 7-9 part, Radix Curcumae 5-8 part.
2. Chinese medicine composition according to claim 1, is characterized in that, described Chinese medicine composition is prepared by the raw material of following weight parts and obtains:
The Rhizoma Atractylodis Macrocephalae 30 parts, Semen pini koraiensis 30 parts, Radix Angelicae Sinensis 30 parts, Rhizoma Dioscoreae 30 parts,
Radix Inulae 28 parts, Ramulus Uncariae Cum Uncis 28 parts, Rhizoma Cyperi 28 parts, Rhodobryum roseum Limpr. 25 parts,
Radix hemerocalis plicatae 25 parts, Massa Medicata Fermentata 25 parts, Rhizoma Polygonati Odorati 20 parts, Radix Scutellariae 20 parts,
Fructus Forsythiae 20 parts, Cortex Magnoliae Officinalis 18 parts, Herba Centellae 18 parts, Fructus Gardeniae 18 parts,
Semen Ziziphi Spinosae 15 parts, Radix Et Caulis Acanthopanacis Senticosi 15 parts, Radix Rhodiolae 15 parts, Herba Taraxaci 15 parts,
Radix Bupleuri 10 parts, Rhizoma Chuanxiong 10 parts, Semen Cassiae 10 parts, Herba Epimedii 10 parts,
Fructus Aurantii Immaturus 8 parts, Fructus Mori 7 parts, Radix Curcumae 5 parts.
3. the preparation method of Chinese medicine composition described in claim 1-2, is characterized in that preferably, and its preparation method is:
(1) get the Rhizoma Atractylodis Macrocephalae, Semen pini koraiensis, Radix Angelicae Sinensis, Rhizoma Dioscoreae, Radix Inulae, Ramulus Uncariae Cum Uncis, Herba Centellae, Fructus Gardeniae, Semen Ziziphi Spinosae, Radix Et Caulis Acanthopanacis Senticosi, Radix Rhodiolae, Herba Taraxaci, Radix Bupleuri, Rhizoma Chuanxiong mix in described ratio, add the ethanol relative to mixture 8 times of quality 95%, reflux, extract, 3 times, each 2 hours, extracting solution merges, and is concentrated into the clear paste that density is 1.25g/ml, 80 DEG C of oven dry, be ground into powder, be complex A;
(2) get surplus stock medicine and add 5 times of soak by water twice, 2 hours first times, second time 1 hour, merges twice decoction liquor, and then drying under reduced pressure obtains density is the extractum of 1.25g/ml, after 80 DEG C of oven dry, is ground into powder, is complex B;
(3) by complex A and complex B mixing and stirring, sterilization obtains capsule product.
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