CN104274254A - Accurate quantification device for animal vein puncture dosing - Google Patents
Accurate quantification device for animal vein puncture dosing Download PDFInfo
- Publication number
- CN104274254A CN104274254A CN201310283743.XA CN201310283743A CN104274254A CN 104274254 A CN104274254 A CN 104274254A CN 201310283743 A CN201310283743 A CN 201310283743A CN 104274254 A CN104274254 A CN 104274254A
- Authority
- CN
- China
- Prior art keywords
- flexible pipe
- hose
- syringe needle
- port
- needle
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 241001465754 Metazoa Species 0.000 title claims abstract description 21
- 210000003462 vein Anatomy 0.000 title abstract description 4
- 238000011002 quantification Methods 0.000 title abstract description 3
- 230000001681 protective effect Effects 0.000 claims description 4
- 239000007788 liquid Substances 0.000 claims description 3
- 239000012530 fluid Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 description 20
- 229940079593 drug Drugs 0.000 description 11
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 6
- 238000010171 animal model Methods 0.000 description 6
- 239000008280 blood Substances 0.000 description 6
- 210000004369 blood Anatomy 0.000 description 6
- 210000004204 blood vessel Anatomy 0.000 description 4
- 238000010586 diagram Methods 0.000 description 4
- 238000007789 sealing Methods 0.000 description 4
- 238000012360 testing method Methods 0.000 description 4
- 239000002699 waste material Substances 0.000 description 4
- 238000002347 injection Methods 0.000 description 3
- 239000007924 injection Substances 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- AOJJSUZBOXZQNB-TZSSRYMLSA-N Doxorubicin Chemical compound O([C@H]1C[C@@](O)(CC=2C(O)=C3C(=O)C=4C=CC=C(C=4C(=O)C3=C(O)C=21)OC)C(=O)CO)[C@H]1C[C@H](N)[C@H](O)[C@H](C)O1 AOJJSUZBOXZQNB-TZSSRYMLSA-N 0.000 description 2
- 238000001467 acupuncture Methods 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 238000010253 intravenous injection Methods 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 210000004761 scalp Anatomy 0.000 description 2
- 241000699670 Mus sp. Species 0.000 description 1
- 241000283973 Oryctolagus cuniculus Species 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 239000002390 adhesive tape Substances 0.000 description 1
- 239000003146 anticoagulant agent Substances 0.000 description 1
- 229940127219 anticoagulant drug Drugs 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 230000023555 blood coagulation Effects 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 229960004679 doxorubicin Drugs 0.000 description 1
- 239000012678 infectious agent Substances 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 208000017169 kidney disease Diseases 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D7/00—Devices or methods for introducing solid, liquid, or gaseous remedies or other materials into or onto the bodies of animals
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Abstract
The invention provides an accurate quantification device for animal vein puncture dosing. The device comprises a syringe needle part, a three-fork connector part and two injectors with scales. The syringe needle part comprises a syringe needle, a syringe needle protection sleeve, a needle handle and a syringe needle hose. A three-fork connector part body is a three-fork hose provided with three end openings, wherein the first end opening is connected with a first hose of the three-fork hose, the second end opening is connected with a second hose of the three-fork hose, and the third end opening is connected with a third hose of the three-fork hose. The first end opening is used for being connected with the syringe needle hose of the syringe needle part, the second end opening and the third end opening are used for being connected with the injectors, and the second hose and the third hose are provided with flow control pulleys. The injectors are used for injecting fluid.
Description
Technical field
The present invention relates to a kind of animals iv puncture administration fine tuning facility.
Background technology
When carrying out zoopery or to treatment of animals, often using venipuncture administration or getting blood technology, usually used is disposable syringe (see accompanying drawing 1) directly administration or get blood.For smaller animal, as rat, mice trailing edge vein, rabbit auricular vein etc., because blood vessel is tiny, it is higher that direct syringe carries out Puncture difficulty, blood vessel often can be caused to be pricked or the situation of the non-intravasation of entry needle, and this situation is without any sign, following consequence can be caused: one, Drug leakage (non-intravasation), changes route of administration when continuing administration; Two, dosage mistake, causes experimental error; Three, precious drug waste; Four, some specific drugs can cause laboratory animal scrap (as rat trailing edge intravenous injection doxorubicin carry out nephropathy model modeling time, if medicine direct intravasation and occur Seepage, rat tail can be caused to come off, again cannot pass through trailing edge intravenous injection other drug, affect subsequent experimental to carry out) even affect the collimation of whole experiment, cause the waste of animal data by the gross, need again to purchase animal by the gross and test, serious waste time and money.This kind of method entry needle is not easily fixed in addition, easily comes off, and infectious agent is understood pollution test stand and then affected operator safety.
Summary of the invention
For above problem, the present invention proposes a kind of animals iv puncture administration fine tuning facility, and described device comprises: needle portion, and it comprises syringe needle, protective sleeve of syringe needle, needle handle, syringe needle flexible pipe; With trident interface section, its main body is the trident flexible pipe with three ports, wherein the first port connects the first flexible pipe of trident flexible pipe, second port connects the second flexible pipe of trident flexible pipe, 3rd port connects the 3rd flexible pipe of trident flexible pipe, first port is used for the syringe needle flexible pipe of connecting needle part, and the second port and the 3rd port, for being connected syringe, the second flexible pipe and the 3rd flexible pipe are provided with flow-control pulley; And the syringe that two with a scale, for injecting liquid by the second port and the 3rd port.
By above technical scheme, accurately can judge whether entry needle is positioned at Ink vessel transfusing and then determines whether continue to push away medicine; Syringe needle can be made to be easy to Ink vessel transfusing fix, make whole injection process safer; Can experiment be made more accurate by accurate quantification dosage, and avoid drug waste; Drug leakage can be avoided, the complete intravasation of guarantee test medicine.
According to hereafter by reference to the accompanying drawings to the detailed description of the specific embodiment of the invention, those skilled in the art will understand above-mentioned and other objects, advantage and feature of the present invention more.
Accompanying drawing explanation
Hereinafter describe specific embodiments more of the present invention with reference to the accompanying drawings by way of example, and not by way of limitation in detail.It should be appreciated by those skilled in the art that these accompanying drawings may not be drawn in proportion.In accompanying drawing:
Accompanying drawing 1 is with disposable syringe venipuncture administration schematic diagram in prior art;
Accompanying drawing 2 is the needle portion schematic diagram of animals iv puncture administration fine tuning facility of the present invention;
Accompanying drawing 3 is the trident interface section schematic diagram of animals iv puncture administration fine tuning facility of the present invention;
Accompanying drawing 4 is the syringe schematic diagram of animals iv puncture administration fine tuning facility of the present invention.
Detailed description of the invention
As shown in Figure 2-4, device of the present invention is divided into following components: (1) needle portion, comprises syringe needle, protective sleeve of syringe needle, needle handle, syringe needle flexible pipe (be similar to scalp acupuncture, but flexible pipe being shorter than scalp acupuncture).2) trident interface section, its main body is three sections of flexible pipes that trident connects, and has A, B, C tri-ports.The A port be connected with the first flexible pipe mates with the syringe needle flexible pipe of needle portion and is connected.Second, third flexible pipe be connected with B, C port respectively there is a flow-control pulley.B, C two ports can be connected with syringe especially disposable syringe, and B, C port has sealing cap for convenience detach in addition.(3) first, second with a scale two disposable syringes mated respectively are held with B, C.Range can be changed as required.All jointings are press-in connection joint.
If need to multiple medicine, the interface (being called multi-fork interface in the present invention) of more multi-fork (being greater than 3 forks) can be designed to.This is used in once-through operation and injects multi-medicament to experimental animal in short period interval.Also may be used for by multiple prong multiple dosing simultaneously.If such as will observe the impact of multi-medicament on experimental animal, need repeatedly to experimental animal puncture in prior art, because puncture interval is longer and wayward, this may cause final experimental data can there is deviation due to puncture interval.And adopt multi-fork Interface design of the present invention, only need carry out one-time puncture to laboratory animal, the interval that avoiding problems repeatedly punctures causes, thus accurately can control administration time or accurately draw blood.Preferably, in order to avoid blood coagulation blocking device, in device, anticoagulant will be added.
This device using method is as follows:
1, first syringe draws normal saline, and evacuation of air is for subsequent use.
2, second syringe draws trial drug, and evacuation of air is for subsequent use.
3, the syringe needle flexible pipe of needle portion is connected with A port, open B port sealing cap, be connected with B port by first syringe (inside having normal saline), keep C port sealing cap tight, the flow-control pulley on second, third flexible pipe connect B, C two-port reaches maximum.Promoting first syringe makes normal saline be full of whole trident interface and syringe needle flexible pipe, bubble-free in whole device.
4, the needle handle of hand-held needle part; remove needle protective cap; syringe needle is inserted animals iv; bend syringe needle flexible pipe or the pulley that B port is adjacent is shut; observe with or without blood back; there is blood back then to retain syringe needle at Ink vessel transfusing, then continue to find blood vessel to optimum position without blood back, then fix flexible pipe and syringe needle with adhesive tape.(normal saline can not cause injury of laboratory animal or affect trial drug dosage.）
5, open C and hold sealing cap, second syringe (inside having trial drug) is held with C and is connected, close the pulley that B port is adjacent, open the pulley that C port is adjacent, push the medicine (the injection volume V pushed required for injection volume V medicine=test theory manages the content volume VC that+C holds flexible pipe) of designated volume/dosage according to the scale of second syringe.
6, the adjacent pulley of C port is closed, open the pulley that B port is adjacent, promote first syringe normal saline according to the scale of first and the medicine remained in flexible pipe is all pushed animal blood vessels (pushing normal saline volume VNS=B holds the content volume VB+A of flexible pipe to hold the content volume V pin of the content volume VA+ syringe needle flexible pipe of flexible pipe), the VNS of comparable Theoretical Calculation suitably more to be pushed, to ensure that medicinal liquid all enters.
Conveniently operate, the flexible pipe of all of the port all can be made as capacity is 0.1ml or 0.2ml, and can prepare different specifications according to animal size and drug dose.
Interchangeable, needle portion of the present invention and three trouble interface sections can directly as one, when can reduce operation like this, the time of connecting needle part and three trouble interface sections, reduces the seam of needle portion and trident interface section owing to repeatedly patching the pollution that may cause simultaneously.
Interchangeable, the syringe needle of needle portion of the present invention can make remaining needle, can stay pin in animal body.Each operation completes rear enclosed syringe needle end, and during subsequent operation, direct connecting needle end, need not puncture again.
Interchangeable, above trident interface section all can replace with multi-fork (prong number is greater than three) interface section.
By above technical scheme, simple to operate, effectively can avoid drug leakage, improve zooperal success rate, reduce animal suffering, save plenty of time and money.
So far, those skilled in the art will recognize that, although multiple exemplary embodiment of the present invention is illustrate and described herein detailed, but, without departing from the spirit and scope of the present invention, still can directly determine or derive other modification many or amendment of meeting the principle of the invention according to content disclosed by the invention.Therefore, scope of the present invention should be understood and regard as and cover all these other modification or amendments.
Claims (1)
1. an animals iv puncture administration fine tuning facility, described device comprises: needle portion, and it comprises syringe needle, protective sleeve of syringe needle, needle handle, syringe needle flexible pipe; With trident interface section, its main body is the trident flexible pipe with three ports, wherein the first port connects the first flexible pipe of trident flexible pipe, second port connects the second flexible pipe of trident flexible pipe, 3rd port connects the 3rd flexible pipe of trident flexible pipe, first port is used for the syringe needle flexible pipe of connecting needle part, and the second port and the 3rd port, for being connected syringe, the second flexible pipe and the 3rd flexible pipe are provided with flow-control pulley; And the syringe that two with a scale, for injecting liquid by the second port and the 3rd port.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310283743.XA CN104274254B (en) | 2013-07-08 | 2013-07-08 | Animal venipuncture administration accurate quantification device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310283743.XA CN104274254B (en) | 2013-07-08 | 2013-07-08 | Animal venipuncture administration accurate quantification device |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN104274254A true CN104274254A (en) | 2015-01-14 |
| CN104274254B CN104274254B (en) | 2016-06-01 |
Family
ID=52249939
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310283743.XA Active CN104274254B (en) | 2013-07-08 | 2013-07-08 | Animal venipuncture administration accurate quantification device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104274254B (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108434547A (en) * | 2018-05-28 | 2018-08-24 | 耿金宏 | A kind of great saphenous varicose vein injection of sclerosing agent device |
Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4096860A (en) * | 1975-10-08 | 1978-06-27 | Mclaughlin William F | Dual flow encatheter |
| GB2088215A (en) * | 1980-06-10 | 1982-06-09 | Wallace Ltd H G | Improvements in intravascular devices |
| CN2669876Y (en) * | 2003-11-12 | 2005-01-12 | 姚力 | Venous transfer lines |
| US20050027233A1 (en) * | 2003-07-30 | 2005-02-03 | Patrice Flaherty | Devices for collecting blood and administering medical fluids |
| US20050197635A1 (en) * | 2003-11-13 | 2005-09-08 | Greydanus Dominique J. | One stage saline lock and intravenous catheter set and method of use |
| CN200963386Y (en) * | 2006-10-26 | 2007-10-24 | 胡营 | Venous injection scalp needle |
| CN201299855Y (en) * | 2008-10-22 | 2009-09-02 | 中国人民解放军第二军医大学 | Drug feed device used for animal in vivo experiments of drug induced infusion phlebitis |
| CN201631335U (en) * | 2010-03-11 | 2010-11-17 | 李斌 | Thoracic puncture needle |
| CN203524804U (en) * | 2013-07-08 | 2014-04-09 | 中国医学科学院北京协和医院 | Accurate proportioning device for drug administration of animal vein puncturing |
-
2013
- 2013-07-08 CN CN201310283743.XA patent/CN104274254B/en active Active
Patent Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4096860A (en) * | 1975-10-08 | 1978-06-27 | Mclaughlin William F | Dual flow encatheter |
| GB2088215A (en) * | 1980-06-10 | 1982-06-09 | Wallace Ltd H G | Improvements in intravascular devices |
| US20050027233A1 (en) * | 2003-07-30 | 2005-02-03 | Patrice Flaherty | Devices for collecting blood and administering medical fluids |
| CN2669876Y (en) * | 2003-11-12 | 2005-01-12 | 姚力 | Venous transfer lines |
| US20050197635A1 (en) * | 2003-11-13 | 2005-09-08 | Greydanus Dominique J. | One stage saline lock and intravenous catheter set and method of use |
| CN200963386Y (en) * | 2006-10-26 | 2007-10-24 | 胡营 | Venous injection scalp needle |
| CN201299855Y (en) * | 2008-10-22 | 2009-09-02 | 中国人民解放军第二军医大学 | Drug feed device used for animal in vivo experiments of drug induced infusion phlebitis |
| CN201631335U (en) * | 2010-03-11 | 2010-11-17 | 李斌 | Thoracic puncture needle |
| CN203524804U (en) * | 2013-07-08 | 2014-04-09 | 中国医学科学院北京协和医院 | Accurate proportioning device for drug administration of animal vein puncturing |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108434547A (en) * | 2018-05-28 | 2018-08-24 | 耿金宏 | A kind of great saphenous varicose vein injection of sclerosing agent device |
Also Published As
| Publication number | Publication date |
|---|---|
| CN104274254B (en) | 2016-06-01 |
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| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| C41 | Transfer of patent application or patent right or utility model | ||
| GR01 | Patent grant | ||
| TA01 | Transfer of patent application right |
Effective date of registration: 20160509 Address after: 100730 Beijing city Shuaifuyuan Dongcheng District No. 1 Applicant after: Beijing Xiehe Hospital, Chinese Academy of Medical Sciences Address before: 102627, Beijing, Daxing District Zhuang Road No. 52 hospital Xing Kang home 10-1-2002 Applicant before: Wang Wei |