CN104257777A - Traditional Chinese medicine composition for treating rhinitis, nasosinusitis and frontal sinusitis and preparation method of traditional Chinese medicine composition - Google Patents
Traditional Chinese medicine composition for treating rhinitis, nasosinusitis and frontal sinusitis and preparation method of traditional Chinese medicine composition Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine composition for treating rhinitis, nasosinusitis and frontal sinusitis. The traditional Chinese medicine composition is prepared by reasonably proportioning twelve traditional Chinese medicines such as ligusticum wallichii, tetrapanax papyriferus, asarum, aluminite, cortex chinnamomi and magnolia flower. The traditional Chinese medicine composition has the effects of dispelling cold and the wind, and dredging and relieving pains, can be used for treating symptoms such as nasal obstruction, nasosinusitis, headache, dizziness, insomnia and amnesia caused by rhinitis, nasosinusitis and frontal sinusitis, and is remarkable in curative effect and high in cure rate.
Description
Technical field
The present invention relates to the field of Chinese medicines, particularly a kind of Chinese medicine composition and preparation method thereof for the treatment of rhinitis, sinusitis, frontal sinusitis.
Background technology
Rhinitis is a kind of otorhinolaryngologic common disease, and mostly reason of showing effect is owing to scratching intranasal with hands, or atmospheric pollution, pay no attention to hygiene, virus and the factors such as bacteriological infection, allergy, Common Cold cause.Rhinitis refers to the inflammation of nasal membrane and submucous tissue, shows as hyperemia or edema, nasal abscess, and nasal obstruction often appears in patient, stream clear water tears, rhinocnesmus, and throat is uncomfortable, the symptoms such as cough; Sinusitis is the diseases associated with inflammation of sinus mucosa, and many and rhinitis exists simultaneously, also claims nose-sinusitis, and nasal obstruction often appears in patient, many pus tears, the symptoms such as headache.
To harm greatly, sickness rate is high, brings great misery to patient, the health of grievous injury patient for rhinitis and sinusitis.In patients with rhinitis, along with the recurrent exerbation of the state of an illness, concurrent one-tenth sinusitis, frontal sinusitis, atrophic rhinitis, the headache of severe one forehead, inappetence, hypomnesis and insomnia, impact study and work.
At present, treatment rhinitis, sinusitis, frontal sinusitis many uses oral traditional Chinese medicine preparation or the means such as antibiotic, puncture are treated, but effect is undesirable, easily develops immunity to drugs, and recurrent exerbation, brings misery to patient in therapeutic process.Inventor, in the over thousands of bar of Chinese medicine record prescription, gropes to study intensively through for many years, develops the rhinitis powder for nasal cavity inflammatory diseases (comprising rhinitis, sinusitis, frontal sinusitis) of the present invention, treating both the principal and secondary aspects of a disease, evident in efficacy.
Summary of the invention
The object of this invention is to provide a kind of Chinese medicine composition effectively treating rhinitis, sinusitis, frontal sinusitis, and the preparation method of this Chinese medicine composition is provided.
The technical solution used in the present invention:
Treat a Chinese medicine composition for rhinitis, sinusitis, frontal sinusitis, it is made up of the raw material of following parts by weight: Rhizoma Chuanxiong 2-3 part, Medulla Tetrapanacis 3-5 part, Margarita powder 9-11 part, Herba Asari 2-3 part, Alumen 6-10 part, Cortex Cinnamomi 3-6 part, Flos Magnoliae 3-5 part, Herba Xanthii 2-3 part, Radix Aconiti Lateralis Preparata 0.8-1 part, Moschus 0.8-1 part, Radix Angelicae Dahuricae 3-5 part, Pedicellus Melo 6-9 part.
As preferably, described Chinese medicine composition is made up of the raw material of following weight portion: Rhizoma Chuanxiong 3 parts, Medulla Tetrapanacis 4 parts, Margarita powder 10 parts, Herba Asari 2 parts, Alumen 8 parts, Cortex Cinnamomi 5 parts, Flos Magnoliae 4 parts, Herba Xanthii 2 parts, Radix Aconiti Lateralis Preparata 0.9 part, 0.9 part, Moschus, the Radix Angelicae Dahuricae 4 parts, Pedicellus Melo 8 parts.
In Chinese medicine composition of the present invention, the effect of each component is as follows:
Rhizoma Chuanxiong: property is pungent, temperature, nontoxic.Return liver, gallbladder meridian, nontoxic, blood-activating and qi-promoting, wind-expelling pain-stopping.For headache, sore, carbuncle and painful swelling, wind and cold pain etc.
Medulla Tetrapanacis: sweet in the mouth, light, cold nature is nontoxic.Attach to the lung and stomach meridians.Stem pith: clearing away heat and promoting diuresis.For hygropyrexia dark coloured urine, the puckery pain of gonorrhea.
Margarita powder: sweet in the mouth is salty, cold in nature, nontoxic.GUIXIN, Liver Channel.For heat-clearing and toxic substances removing, tranquillizing the mind by relieving convulsion, suppressing the hyperactive liver improving eyesight, supplement calcium, aphtha of the mouth and tongue, throat is burst rotten, row's endogenous toxin.
Herba Asari: property is pungent, temperature.Return lung, kidney, the heart, liver, gallbladder, spleen channel.Cold expelling dispels the wind, pain relieving, and warming the lung to resolve fluid-retention is sensible.For anemofrigid cold, nasal obstruction nasal sinusitis, headache, toothache, rheumatic arthralgia, phlegm retention is breathed with cough.
Alumen: sour-puckery flavor, cold in nature.Return lung, spleen, stomach, large intestine channel.Crystallization: dampness of eliminating the phlegm, removing toxic substances parasite killing, antidiarrheal is stopped blooding.For sore throat, Ting discharging ear, polyp in nose, scabies eczema, swollen ulcer drug, burn due to hot liquid or fire, aphtha of the mouth and tongue, marginal blepharitis eye.
Cortex Cinnamomi: property is pungent, sweet, heat.Return kidney, spleen, the heart, Liver Channel.There is complement sun, warming the spleen and stomach, coronary circulation-promoting pain-relieving, liver and kidney tonifying effect.
Flos Magnoliae: acrid in the mouth, warm in nature.Attach to the lung and stomach meridians.There is expelling pathogenic wind and restoring the functions of orifices in face, sharp nine orifices, the effect of clearance arteries and veins.For headache, nasal sinusitis, has a stuffy nose obstructed, toothache.
Herba Xanthii: bitter in the mouth, pungent, cold nature.Return lung, spleen, Liver Channel.There is expelling pathogenic wind from the body surface, the effect of a surname's clearing the nasal passage.For flu, wind syndrome of head, dizzy, nasal sinusitis, conjunctival congestion, corneal nebula, pathogenic wind-warm arthralgia pain, contracture is numb, wind leprosy, furuncle, scabies, skin pruritus, hemorrhoid, dysentery.
Radix Aconiti Lateralis Preparata: acrid in the mouth, sweet, hot in nature, poisonous.GUIXIN, spleen, kidney channel.There is the effects such as removing toxic substances, removing obstruction for relieving pain.
Moschus: have stronger penetration, can play only scorching ventilation effect by Nasacort.
The Radix Angelicae Dahuricae: acrid in the mouth, warm in nature, nontoxic.Return lung, spleen, stomach warp.Root: expelling wind and removing dampness, understand things pain-stopping, detumescence and apocenosis.For headache due to common cold, supraorbital bone pain, nasal obstruction, nasal sinusitis, toothache, leucorrhea, skin infection swells and ache.
Pedicellus Melo: bitter in the mouth, cold in nature, poisonous.Return spleen, stomach warp.Tell wind-phlegm dyspepsia, removing water retention by purgation is wet stops drink.For sputum dyspepsia, be jammed Shangwan, in the heart painful abdominal mass stalk, wind-phlegm epilepsy, jaundice due to damp-heat, extremity edema, nasal obstruction, sore throat.
To sum up, all medicines share and play that cold expelling dispels the wind, the merit of understand things pain-stopping altogether.Be used for the treatment of the symptom such as nasal obstruction, nasal sinusitis, headache, dizziness, insomnia forgetfulness caused by nasal cavity inflammatory diseases.
Present invention also offers the preparation method of described Chinese medicine composition, comprise the following steps:
A): according to described raw material and proportioning, weigh for subsequent use;
B): get described Rhizoma Chuanxiong, Medulla Tetrapanacis, Herba Asari, Alumen, Cortex Cinnamomi, Flos Magnoliae, Herba Xanthii, Radix Aconiti Lateralis Preparata, the Radix Angelicae Dahuricae, Pedicellus Melo, 120 object powder are ground to;
C): get Margarita powder, Moschus join in the powder of step b) gained continue development, cross 120 mesh sieves, mix homogeneously, obtains powder, or the powder of gained and Oleum Sesami are reconciled into paste, wraps up this paste, obtain suppository with sterile gauze.
Using method: dip about 0.1 gram, described powder with aseptic medical absorbent cotton, fill in nasal cavity, indwelling 20min; Or described powder and Oleum Sesami are reconciled into paste, wrap up this paste with sterile gauze, obtain rhinitis suppository, fill in nasal cavity, indwelling 20min.
Points for attention: patient is not with the cotton swab of application in TCM band rod of the present invention, daytime, use, wanted use in bed, in order to avoid suck intranasal, anemia of pregnant woman is forbidden, and guards against damp.
Shown by clinical trial, this Chinese medicine composition and powder thereof, suppository have good therapeutic effect to nasal cavity inflammatory diseases:
1) can effectively improve nasal cavity immunity power, thoroughly remove the bacteriotoxin of nasal cavity, Be very effective;
2) instant effect, transference cure after three days, within 90 days, return to one's perfect health, cure rate is up to 98%;
3) do not take medicine, do not have an injection, No operation, no pain, pure Chinese medicine ingredients, has no side effect;
4) present invention also offers the preparation method of Chinese medicine composition, the method is easy and simple to handle, with low cost, easy to use, portable, practical.
Detailed description of the invention
Following examples further illustrate of the present invention, instead of limit its scope.Wherein used raw material and reagent, all can be buied by market.
Embodiment 1
The present embodiment Chinese medicine composition comprises the raw material of following weight: Rhizoma Chuanxiong 3g, Medulla Tetrapanacis 4g, Margarita powder 10g, Herba Asari 2g, Alumen 8g, Cortex Cinnamomi 5g, Flos Magnoliae 4g, Herba Xanthii 2g, Radix Aconiti Lateralis Preparata 0.9g, Moschus 0.9g, Radix Angelicae Dahuricae 4g, Pedicellus Melo 8g.
The preparation method of this Chinese medicine composition:
A): take raw material;
B): get described Rhizoma Chuanxiong, Medulla Tetrapanacis, Herba Asari, Alumen, Cortex Cinnamomi, Flos Magnoliae, Herba Xanthii, Radix Aconiti Lateralis Preparata, the Radix Angelicae Dahuricae, Pedicellus Melo, 120 object powder are ground to;
C): get Margarita powder, Moschus join in the powder of step b) gained continue development, cross 120 mesh sieves, mix homogeneously, obtains powder, bottles for subsequent use.
Embodiment 2
The present embodiment Chinese medicine composition comprises the raw material of following weight: Rhizoma Chuanxiong 2g, Medulla Tetrapanacis 3g, Margarita powder 9g, Herba Asari 2g, Alumen 6g, Cortex Cinnamomi 3g, Flos Magnoliae 3g, Herba Xanthii 2g, Radix Aconiti Lateralis Preparata 0.8g, Moschus 0.8g, Radix Angelicae Dahuricae 3g, Pedicellus Melo 6g;
The preparation method of this Chinese medicine composition:
A): take following raw material: Rhizoma Chuanxiong 2g, Medulla Tetrapanacis 3g, Margarita powder 9g, Herba Asari 2g, Alumen 6g, Cortex Cinnamomi 3g, Flos Magnoliae 3g, Herba Xanthii 2g, Radix Aconiti Lateralis Preparata 0.8g, Moschus 0.8g, Radix Angelicae Dahuricae 3g, Pedicellus Melo 6g;
B): get described Rhizoma Chuanxiong, Medulla Tetrapanacis, Herba Asari, Alumen, Cortex Cinnamomi, Flos Magnoliae, Herba Xanthii, Radix Aconiti Lateralis Preparata, the Radix Angelicae Dahuricae, Pedicellus Melo, 120 object powder are ground to;
C): get Margarita powder, Moschus join in the powder of step b) gained continue development, cross 120 mesh sieves, mix homogeneously, obtains powder, bottles for subsequent use.
Embodiment 3
The present embodiment Chinese medicine composition comprises the raw material of following weight: Rhizoma Chuanxiong 3g, Medulla Tetrapanacis 5g, Margarita powder 11g, Herba Asari 3g, Alumen 10g, Cortex Cinnamomi 6g, Flos Magnoliae 5g, Herba Xanthii 3g, Radix Aconiti Lateralis Preparata 1g, Moschus 1g, Radix Angelicae Dahuricae 5g, Pedicellus Melo 9g.
The preparation method of this Chinese medicine composition:
A) raw material is taken;
B): get described Rhizoma Chuanxiong, Medulla Tetrapanacis, Herba Asari, Alumen, Cortex Cinnamomi, Flos Magnoliae, Herba Xanthii, Radix Aconiti Lateralis Preparata, the Radix Angelicae Dahuricae, Pedicellus Melo, 120 object powder are ground to;
C): get Margarita powder, Moschus join in the powder of step b) gained continue development, cross 120 mesh sieves, mix homogeneously, obtains powder, bottles for subsequent use.
Embodiment 4
The present embodiment Chinese medicine composition comprises the raw material of following weight: Rhizoma Chuanxiong 3g, Medulla Tetrapanacis 4g, Margarita powder 10g, Herba Asari 2g, Alumen 7g, Cortex Cinnamomi 5g, Flos Magnoliae 5g, Herba Xanthii 3g, Radix Aconiti Lateralis Preparata 0.8g, Moschus 0.9g, Radix Angelicae Dahuricae 5g, Pedicellus Melo 8g.
The preparation method of this Chinese medicine composition:
A): take raw material;
B): get described Rhizoma Chuanxiong, Medulla Tetrapanacis, Herba Asari, Alumen, Cortex Cinnamomi, Flos Magnoliae, Herba Xanthii, Radix Aconiti Lateralis Preparata, the Radix Angelicae Dahuricae, Pedicellus Melo, 120 object powder are ground to;
C): get Margarita powder, Moschus join in the powder of step b) gained continue development, cross 120 mesh sieves, mix homogeneously, obtains powder, bottles for subsequent use.
Embodiment 5
The present embodiment Chinese medicine composition comprises the raw material of following weight: Rhizoma Chuanxiong 3g, Medulla Tetrapanacis 5g, Margarita powder 9g, Herba Asari 3g, Alumen 8g, Cortex Cinnamomi 4g, Flos Magnoliae 4g, Herba Xanthii 3g, Radix Aconiti Lateralis Preparata 0.8g, Moschus 0.8g, Radix Angelicae Dahuricae 4g, Pedicellus Melo 7g.
The preparation method of this Chinese medicine composition:
A): take raw material;
B): get described Rhizoma Chuanxiong, Medulla Tetrapanacis, Herba Asari, Alumen, Cortex Cinnamomi, Flos Magnoliae, Herba Xanthii, Radix Aconiti Lateralis Preparata, the Radix Angelicae Dahuricae, Pedicellus Melo, 120 object powder are ground to;
C): get Margarita powder, Moschus join in the powder of step b) gained continue development, cross 120 mesh sieves, mix homogeneously, obtains powder, bottles for subsequent use.
Embodiment 6
The present embodiment Chinese medicine composition comprises the raw material of following weight: Rhizoma Chuanxiong 3g, Medulla Tetrapanacis 4g, Margarita powder 10g, Herba Asari 3g, Alumen 8g, Cortex Cinnamomi 5g, Flos Magnoliae 5g, Herba Xanthii 2g, Radix Aconiti Lateralis Preparata 0.9g, Moschus 0.9g, Radix Angelicae Dahuricae 4g, Pedicellus Melo 8g.
The preparation method of this Chinese medicine composition:
A): take raw material;
B): get described Rhizoma Chuanxiong, Medulla Tetrapanacis, Herba Asari, Alumen, Cortex Cinnamomi, Flos Magnoliae, Herba Xanthii, Radix Aconiti Lateralis Preparata, the Radix Angelicae Dahuricae, Pedicellus Melo, 120 object powder are ground to;
C): get Margarita powder, Moschus join in the powder of step b) gained continue development, cross 120 mesh sieves, mix homogeneously, obtain powder, add the Oleum Sesami of the minimum dose that can form suppository, reconcile into paste, wrap up this paste with sterile gauze, obtain rhinitis suppository.
The clinical practice test of embodiment 7 Chinese medicine composition
Select meet diagnostic criteria out-patient 240 example, 16 ~ 64 years old age, be make a definite diagnosis allergic rhinitis, atrophic rhinitis, chronic rhinitis, seasonal rhinitis, nasal abscess, sinusitis, frontal sinusitis patient; This 240 example is divided at random treatment by Chinese herbs group 120 example, matched group 120 example; Two groups of ages, rhinitis types, through statistical procedures there was no significant difference, there is comparability.
Treatment by Chinese herbs group: the Chinese medicine composition using embodiment 1 to prepare, dips 0.1 gram, described powder with aseptic absorbent cotton at every turn, fill in nasal cavity, indwelling 20min, every day 3-5 time.
Matched group: use trivial rhinitis sheet (as joined rhinitis tablet in Wuhan Zhonglian Pharmaceutical Group Co. Ltd.'s production), each 2,3 times on the one, warm water delivery service.
Table 1 criterion of therapeutical effect
Curative effect | Evaluation criterion |
Effective | Medication 4 days cardinal symptoms alleviate and/or recovery from illness in 15 days |
Effectively | Medication 8 days cardinal symptoms alleviate and/or recovery from illness in 26 days |
Invalid | Medication 8 days cardinal symptoms do not alleviate and do not heal for 26 days |
Table 2 liang group Clinical efficacy comparison
? | Case load | Effective | Effectively | Invalid | Total effective rate (%) | Inefficiency (%) |
Treatment by Chinese herbs group | 120 | 80 | 38 | 2 | 98.3 | 1.7 |
Matched group | 120 | 64 | 42 | 14 | 88.3 | 11.7 |
As can be seen from the above table, in treatment by Chinese herbs group, total effective rate is 98.3%, matched group is 88.3%, the two is compared, the total effective rate of Chinese medicine composition prepared by embodiment 1 is significantly higher than matched group, it can thus be appreciated that Chinese medicine composition prepared by embodiment 1 can significantly treat nasal cavity inflammatory diseases, and evident in efficacy, instant effect is better than matched group.
Model case
Case 1: Zhang Da, man, 19 years old now, Cheng Jiazhuan people from village, Dingzhou City in Hebei Province, suffered from sinusitis in 15 years old, invalid through hospitalize for many years, and with the present invention's treatment, 4 days take effect, and recovery from illness in two months, joins the army, do not violate so far for 17 years old.
Case 2: Cheng Tao, man, 40 years old now, Cheng Jiazhuan people from village, Dingzhou City in Hebei Province, suffered from rhinitis for many years, invalid with a lot of medicine, fails to respond to any medical treatment for many years, used Chinese medicine of the present invention to take effect for 3 days, and transference cure recovery from illness in 26 days, returns to one's perfect health, do not violate so far for 90 days.
Case 3: state puts down, man, 56 years old now, Hebei Anguo people, suffered from rhinitis for many years, and use the embodiment of the present invention 1 Chinese medicine powder, every day 5 times, each indwelling 20min, 8 days take effect, and a wheat harvesting period recovery from illness, does not violate so far.
Case 4: second place, man, 36 years old, great Xin Zhuan people from village, Dingzhou, Hebei province, suffers from chronic rhinitis for many years, uses Chinese medicine composition of the present invention, paste is reconciled into Oleum Sesami, wrap up this paste with sterile gauze, obtain rhinitis suppository, fill in nasal cavity, every day 4 times, each indwelling 20min, treats 5 days Be very effective, recovery from illness in 20 days.
Case 5: Li Yan, female, 22 years old, Hebei Anguo people, suffered from chronic rhinitis, repeatedly falls ill, and once takes trivial rhinitis tablet, poor effect, comes to go to a doctor.Medical period, use embodiment 1 Chinese medicine powder in the present invention, every day 3 times, each indwelling 20min, treats 3 days symptoms and alleviates, and first quarter moon is fully recovered.
Claims (4)
1. treat a Chinese medicine composition for rhinitis, sinusitis, frontal sinusitis, it is characterized in that it is made up of the raw material of following parts by weight: Rhizoma Chuanxiong 2-3 part, Medulla Tetrapanacis 3-5 part, Margarita powder 9-11 part, Herba Asari 2-3 part, Alumen 6-10 part, Cortex Cinnamomi 3-6 part, Flos Magnoliae 3-5 part, Herba Xanthii 2-3 part, Radix Aconiti Lateralis Preparata 0.8-1 part, Moschus 0.8-1 part, Radix Angelicae Dahuricae 3-5 part, Pedicellus Melo 6-9 part.
2. a kind of Chinese medicine composition for the treatment of rhinitis, sinusitis, frontal sinusitis according to claim 1, is characterized in that it is made up of the raw material of following parts by weight: Rhizoma Chuanxiong 3 parts, Medulla Tetrapanacis 4 parts, Margarita powder 10 parts, Herba Asari 2 parts, Alumen 8 parts, Cortex Cinnamomi 5 parts, Flos Magnoliae 4 parts, Herba Xanthii 2 parts, Radix Aconiti Lateralis Preparata 0.9 part, 0.9 part, Moschus, the Radix Angelicae Dahuricae 4 parts, Pedicellus Melo 8 parts.
3. a kind of preparation method of Chinese medicine composition for the treatment of rhinitis, sinusitis, frontal sinusitis as claimed in claim 1 or 2, is characterized in that its making step is:
A): according to described raw material and proportioning, weigh for subsequent use;
B): get described Rhizoma Chuanxiong, Medulla Tetrapanacis, Herba Asari, Alumen, Cortex Cinnamomi, Flos Magnoliae, Herba Xanthii, Radix Aconiti Lateralis Preparata, the Radix Angelicae Dahuricae, Pedicellus Melo, 120 object powder are ground to;
C): get Margarita powder, Moschus join in the powder of step b) gained continue development, cross 120 mesh sieves, mix homogeneously, obtains powder, bottles for subsequent use.
4. a kind of preparation method of Chinese medicine composition for the treatment of rhinitis, sinusitis, frontal sinusitis according to claim 3, is characterized in that: by step c) powder of gained and Oleum Sesami reconciles into paste, and wrap up this paste with sterile gauze, obtain suppository.
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