CN104225567A - Fish medicine for treating ichthyophthiriasis - Google Patents

Fish medicine for treating ichthyophthiriasis Download PDF

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Publication number
CN104225567A
CN104225567A CN201410520781.7A CN201410520781A CN104225567A CN 104225567 A CN104225567 A CN 104225567A CN 201410520781 A CN201410520781 A CN 201410520781A CN 104225567 A CN104225567 A CN 104225567A
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parts
fish
fish medicine
medicine
ichthyophthiriasis
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CN201410520781.7A
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刘欢
蒋雅美
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Zhejiang Ocean University ZJOU
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Zhejiang Ocean University ZJOU
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Abstract

The invention provides a fish medicine for treating ichthyophthiriasis. The fish medicine is characterized by being prepared from the following raw materials in parts by weight: 50-80 parts of cortex meliae, 30-40 parts of radix sophorae flavescentis, 10-20 parts of ginger, 1-5 parts of pepper, 5-10 parts of mung bean, 5-10 parts of codonopsis pilosula and 15-25 parts of chrysanthemum indicum. The fish medicine has the advantages of good prevention effect, little side effect and no pollution to fish ponds.

Description

A kind of fish medicine for the treatment of ichthyophthiriasis
Technical field
The invention belongs to fish medicine, specifically a kind of fish medicine for the treatment of ichthyophthiriasis.
Background technology
Ichthyophthiriasis is a kind of common fish diseases, and sick fish body surface and the gill lamella are covered with polypide and the cyst of white point-like, naked eyes are visible, therefore are ichthyophthiriasis again.Body surface head, trunk and fin ray place mucus showed increased, mix with polypide, seemingly have thin film, ichthyophthiriasis has obvious morbidity season, the spring, autumn south just winter are all epidemic season.After ripe little melonworm departs from fish body, the transparent and resilient cyst of body secretes, sinks under water or is attached on pasture and water and canebreak, then starts division.After 9 to 10 divisions, form 300 to 1000 larvas.Larva, 15 to 20 degrees Celsius time, through 24 hours, departs from cyst, swims in the water, and attack to host.Therefore little melonworm is with the breeding of cyst form and propagator generation.Cultivation density is large, the pond of water quality inferiority easily occurs.Without host specificity, any Fish all can be attacked, are fallen ill.In the past for the fish medicine of this disease, preventive effect was bad, and side effect is large, has certain pollution to fishpond.
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Summary of the invention
In order to solve the problems of the technologies described above, the invention provides a kind of fish medicine for the treatment of ichthyophthiriasis.
Treat a fish medicine for ichthyophthiriasis, it is characterized in that it is made up of the raw material of following parts by weight: Cortex Meliae 50-80 parts, Radix Sophorae Flavescentis 30-40 parts, 10-20 parts, Rhizoma Zingiberis Recens, 1-5 parts, Fructus Capsici, 5-10 parts, Semen phaseoli radiati, Radix Codonopsis 5-10 parts, 15-25 parts, Herba Dendranthematis indici.
Described a kind of fish medicine for the treatment of ichthyophthiriasis, is characterized in that it is made up of the raw material of following parts by weight: Cortex Meliae 60-70 parts, Radix Sophorae Flavescentis 33-37 parts, 13-17 parts, Rhizoma Zingiberis Recens, 2-4 parts, Fructus Capsici, 6-8 parts, Semen phaseoli radiati, Radix Codonopsis 6-8 parts, 18-22 parts, Herba Dendranthematis indici.
Described a kind of fish medicine for the treatment of ichthyophthiriasis, is characterized in that it is made up of the raw material of following parts by weight: Cortex Meliae 65 parts, Radix Sophorae Flavescentis 35 parts, 15 parts, Rhizoma Zingiberis Recens, 3 parts, Fructus Capsici, 7 parts, Semen phaseoli radiati, Radix Codonopsis 7 parts, 20 parts, Herba Dendranthematis indici.
Described a kind of fish medicine for the treatment of ichthyophthiriasis, is characterized in that its dosage form is granule.
The preparation method of described fish medicine, is characterized in that comprising the following steps:
1) each crude drug is ground into coarse powder, extracts by percolation, use 70% ethanol as solvent, flood after 24 hours, with the speed slowly percolation of per kilogram by 10ml per minute, collect the liquid of filtering of medical material 10 times of weight, reclaim ethanol to without alcohol taste, obtain alcohol extract and medicinal residues, for subsequent use;
2) medicinal residues are added 10 times of water gagings again, decoct 2 hours, be separated medicinal liquid;
3) by step 2) gained medicinal residues add 10 times of water gagings again, decoct 2 hours, are separated medicinal liquid;
4) by step 2) and step 3) secondary decoction liquor, filter with 100 mesh sieves, filtrate is concentrated into relative density when being 1.02, and with tubular-bowl centrifuge with the centrifugation of 20000 revs/min, concentration of liquid medicine is about 1.05 to relative density, obtains extracting solution;
5) add the alcohol extract that volatile oil clathrate compound and step 1) obtain, then it is appropriate to add dextrin, stirs, adds appropriate distilled water, final that extracting solution relative density be 1.07;
6) filter with 100 mesh sieves, filtrate spray-dried after powder, dryly extrude grain, obtain granule, inspection, packaging.
The using method of described fish medicine, is characterized in that described fish medicine to admix mix homogeneously in feedstuff by 0.1%-0.3% of fish body weight.
A kind of fish medicine for the treatment of ichthyophthiriasis of the present invention, preventive effect is good, and side effect is little, pollution-free to fishpond.
Detailed description of the invention
Embodiment 1
Cortex Meliae 6000g, Radix Sophorae Flavescentis 3700g, Rhizoma Zingiberis Recens 1300g, Fructus Capsici 400g, Semen phaseoli radiati 600g, Radix Codonopsis 800g, Herba Dendranthematis indici 1800g.
Preparation method:
1) each crude drug is ground into coarse powder, extracts by percolation, use 70% ethanol as solvent, flood after 24 hours, with the speed slowly percolation of per kilogram by 10ml per minute, collect the liquid of filtering of medical material 10 times of weight, reclaim ethanol to without alcohol taste, obtain alcohol extract and medicinal residues, for subsequent use;
2) medicinal residues are added 10 times of water gagings again, decoct 2 hours, be separated medicinal liquid;
3) by step 2) gained medicinal residues add 10 times of water gagings again, decoct 2 hours, are separated medicinal liquid;
4) by step 2) and step 3) secondary decoction liquor, filter with 100 mesh sieves, filtrate is concentrated into relative density when being 1.02, and with tubular-bowl centrifuge with the centrifugation of 20000 revs/min, concentration of liquid medicine is about 1.05 to relative density, obtains extracting solution;
5) add the alcohol extract that volatile oil clathrate compound and step 1) obtain, then it is appropriate to add dextrin, stirs, adds appropriate distilled water, final that extracting solution relative density be 1.07;
6) filter with 100 mesh sieves, filtrate spray-dried after powder, dryly extrude grain, obtain granule, inspection, packaging.
Described fish medicine is admixed mix homogeneously in feedstuff by 0.2% of fish body weight.
Embodiment 2
Cortex Meliae 6500g, Radix Sophorae Flavescentis 3500g, Rhizoma Zingiberis Recens 1500g, Fructus Capsici 300g, Semen phaseoli radiati 700g, Radix Codonopsis 700g, Herba Dendranthematis indici 2000g.
Preparation method is with embodiment 1.
Described fish medicine is admixed mix homogeneously in feedstuff by 0.2% of fish body weight.
Embodiment 3
Cortex Meliae 7000g, Radix Sophorae Flavescentis 3300g, Rhizoma Zingiberis Recens 1700g, Fructus Capsici 200g, Semen phaseoli radiati 800g, Radix Codonopsis 600g, Herba Dendranthematis indici 2200g.
Preparation method is with embodiment 1.
Described fish medicine is admixed mix homogeneously in feedstuff by 0.2% of fish body weight.
On July 1st, 2014 was to July 10, the fish medicine effect experimental of 10 days has by a definite date been carried out in fish farm, Zhoushan, Zhejiang Province, the fish that 400 are infected ichthyophthiriasis is divided into 4 groups, wherein 1 group is matched group, the common fish medicine of feeding, the fish medicine of other 3 groups difference feeding embodiments every day 1-3, result is as shown in table 1:
Table 1: the effect table of fish medicine of the present invention
? Effective percentage Untoward reaction rate
Embodiment 1 97% 3%
Embodiment 2 100% 1%
Embodiment 3 97% 2%
Common fish medicine 73% 15%
As can be seen here, adopt fish medicine of the present invention good to ichthyophthiriasis therapeutic effect, side effect is little.
The foregoing is only preferred embodiment of the present invention, not in order to limit the present invention, all any amendments done within the spirit and principles in the present invention, equivalent replacement and improvement etc., be all included within protection scope of the present invention.

Claims (6)

1. treat a fish medicine for ichthyophthiriasis, it is characterized in that it is made up of the raw material of following parts by weight: Cortex Meliae 50-80 parts, Radix Sophorae Flavescentis 30-40 parts, 10-20 parts, Rhizoma Zingiberis Recens, 1-5 parts, Fructus Capsici, 5-10 parts, Semen phaseoli radiati, Radix Codonopsis 5-10 parts, 15-25 parts, Herba Dendranthematis indici.
2. a kind of fish medicine for the treatment of ichthyophthiriasis as claimed in claim 1, is characterized in that it is made up of the raw material of following parts by weight: Cortex Meliae 60-70 parts, Radix Sophorae Flavescentis 33-37 parts, 13-17 parts, Rhizoma Zingiberis Recens, 2-4 parts, Fructus Capsici, 6-8 parts, Semen phaseoli radiati, Radix Codonopsis 6-8 parts, 18-22 parts, Herba Dendranthematis indici.
3. a kind of fish medicine for the treatment of ichthyophthiriasis as claimed in claim 1, is characterized in that it is made up of the raw material of following parts by weight: Cortex Meliae 65 parts, Radix Sophorae Flavescentis 35 parts, 15 parts, Rhizoma Zingiberis Recens, 3 parts, Fructus Capsici, 7 parts, Semen phaseoli radiati, Radix Codonopsis 7 parts, 20 parts, Herba Dendranthematis indici.
4., as a kind of fish medicine for the treatment of ichthyophthiriasis in claims 1 to 3 as described in any one, it is characterized in that its dosage form is granule.
5. the preparation method of fish medicine as claimed in claim 4, is characterized in that comprising the following steps:
1) each crude drug is ground into coarse powder, extracts by percolation, use 70% ethanol as solvent, flood after 24 hours, with the speed slowly percolation of per kilogram by 10ml per minute, collect the liquid of filtering of medical material 10 times of weight, reclaim ethanol to without alcohol taste, obtain alcohol extract and medicinal residues, for subsequent use;
2) medicinal residues are added 10 times of water gagings again, decoct 2 hours, be separated medicinal liquid;
3) by step 2) gained medicinal residues add 10 times of water gagings again, decoct 2 hours, are separated medicinal liquid;
4) by step 2) and step 3) secondary decoction liquor, filter with 100 mesh sieves, filtrate is concentrated into relative density when being 1.02, and with tubular-bowl centrifuge with the centrifugation of 20000 revs/min, concentration of liquid medicine is about 1.05 to relative density, obtains extracting solution;
5) add the alcohol extract that volatile oil clathrate compound and step 1) obtain, then it is appropriate to add dextrin, stirs, adds appropriate distilled water, final that extracting solution relative density be 1.07;
6) filter with 100 mesh sieves, filtrate spray-dried after powder, dryly extrude grain, obtain granule, inspection, packaging.
6. the using method of fish medicine as claimed in claim 4, is characterized in that described fish medicine to admix mix homogeneously in feedstuff by 0.1%-0.3% of fish body weight.
CN201410520781.7A 2014-09-29 2014-09-29 Fish medicine for treating ichthyophthiriasis Pending CN104225567A (en)

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Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105581050A (en) * 2015-12-20 2016-05-18 重庆井然农业发展有限公司 Fodder for preventing fancy carps from suffering from ichthyophthiriasis
CN105641166A (en) * 2016-01-21 2016-06-08 苏州派腾生物医药科技有限公司 Traditional Chinese medicine composition for treating fresh water ichthyophthiriasis
CN105641072A (en) * 2016-01-21 2016-06-08 苏州派腾生物医药科技有限公司 Fish drug for treating ichthyophthiriasis
CN105661104A (en) * 2016-01-21 2016-06-15 苏州派腾生物医药科技有限公司 Feed additive resistant to Ichthyophthiriasis in fish
CN106038682A (en) * 2016-07-18 2016-10-26 暨南大学 Chinese herbal medicine compound preparation for preventing and treating chthyophthirius multifilis for fish as well as preparation and application of Chinese herbal medicine compound preparation
CN106110249A (en) * 2016-07-14 2016-11-16 宁波科瑞特动物药业有限公司 For preventing and treating the medicament composition of Fish ichthyophthiriasis
CN107007713A (en) * 2017-05-08 2017-08-04 四川省农业科学院水产研究所 A kind of Chinese medicine and preparation method for preventing and treating C. guichenoti ich
CN107410764A (en) * 2017-07-20 2017-12-01 通化师范学院 A kind of Chinese herbal feed additive for preventing golden trout ich and application thereof

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JP2003226608A (en) * 2001-11-30 2003-08-12 Daiko Tekku Kk Prophylactic agent for mite and method for prophylaxis thereof
CN102973908A (en) * 2011-09-07 2013-03-20 赵林斌 Traditional Chinese medicine formula for treating ichthyophthiriasis in fish
CN103611111A (en) * 2013-11-13 2014-03-05 赵林斌 Composition for treating fish Ichthyophthiriasis
CN103623068A (en) * 2013-11-13 2014-03-12 江西省水产科学研究所 Drug for treating ichthyophthiriasis in fish

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Publication number Priority date Publication date Assignee Title
JP2003226608A (en) * 2001-11-30 2003-08-12 Daiko Tekku Kk Prophylactic agent for mite and method for prophylaxis thereof
CN102973908A (en) * 2011-09-07 2013-03-20 赵林斌 Traditional Chinese medicine formula for treating ichthyophthiriasis in fish
CN103611111A (en) * 2013-11-13 2014-03-05 赵林斌 Composition for treating fish Ichthyophthiriasis
CN103623068A (en) * 2013-11-13 2014-03-12 江西省水产科学研究所 Drug for treating ichthyophthiriasis in fish

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Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105581050A (en) * 2015-12-20 2016-05-18 重庆井然农业发展有限公司 Fodder for preventing fancy carps from suffering from ichthyophthiriasis
CN105641166A (en) * 2016-01-21 2016-06-08 苏州派腾生物医药科技有限公司 Traditional Chinese medicine composition for treating fresh water ichthyophthiriasis
CN105641072A (en) * 2016-01-21 2016-06-08 苏州派腾生物医药科技有限公司 Fish drug for treating ichthyophthiriasis
CN105661104A (en) * 2016-01-21 2016-06-15 苏州派腾生物医药科技有限公司 Feed additive resistant to Ichthyophthiriasis in fish
CN106110249A (en) * 2016-07-14 2016-11-16 宁波科瑞特动物药业有限公司 For preventing and treating the medicament composition of Fish ichthyophthiriasis
CN106038682A (en) * 2016-07-18 2016-10-26 暨南大学 Chinese herbal medicine compound preparation for preventing and treating chthyophthirius multifilis for fish as well as preparation and application of Chinese herbal medicine compound preparation
CN107007713A (en) * 2017-05-08 2017-08-04 四川省农业科学院水产研究所 A kind of Chinese medicine and preparation method for preventing and treating C. guichenoti ich
CN107007713B (en) * 2017-05-08 2020-11-06 四川省农业科学院水产研究所 Traditional Chinese medicine for preventing and treating ichthyophthirius rotundifolia ichthyophthirius diseases and preparation method
CN107410764A (en) * 2017-07-20 2017-12-01 通化师范学院 A kind of Chinese herbal feed additive for preventing golden trout ich and application thereof

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Application publication date: 20141224