CN104222534A - Application of sodium butyrate to feed for rice field eels - Google Patents

Application of sodium butyrate to feed for rice field eels Download PDF

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Publication number
CN104222534A
CN104222534A CN201410430326.8A CN201410430326A CN104222534A CN 104222534 A CN104222534 A CN 104222534A CN 201410430326 A CN201410430326 A CN 201410430326A CN 104222534 A CN104222534 A CN 104222534A
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CN
China
Prior art keywords
feed
sodium butyrate
rice field
eel
fish meal
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201410430326.8A
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Chinese (zh)
Inventor
胡毅
张俊智
钟蕾
李浙烽
余荣
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KANGDEQUAN FEED CO Ltd HANGZHOU
Hunan Agricultural University
Original Assignee
KANGDEQUAN FEED CO Ltd HANGZHOU
Hunan Agricultural University
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Application filed by KANGDEQUAN FEED CO Ltd HANGZHOU, Hunan Agricultural University filed Critical KANGDEQUAN FEED CO Ltd HANGZHOU
Priority to CN201410430326.8A priority Critical patent/CN104222534A/en
Publication of CN104222534A publication Critical patent/CN104222534A/en
Pending legal-status Critical Current

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Abstract

The invention discloses application of sodium butyrate to a feed for rice field eels, and a feed for the rice field eels. The content of fish meal in the feed is smaller than 35 percent, the content of plant protein sources in the feed is greater than 40 percent, sodium butyrate is added to the feed, and 0.5-1g of micro-capsule sodium butyrate is added to each kilogram of feed. According to the feed, sodium butyrate is added to the feed for the rice field eels in a manner of a feed additive, mainly aiming at the problems of high price of the fish meal, high formula cost, and structural damage of an intestinal tract form and reduced immunity and growth caused by reduced content of the fish meal in an aquatic feed formula and consumption of a large quantity of plant protein sources, the intestinal tract form of the rice field eels is effectively restored, the absorbing capacity of the intestinal track and the immunity of an organism are enhanced, the growth of the rice field eels is promoted, the feed utilization rate is increased, the application of the plant protein sources in an aquatic feed is improved, the feed cost is lowered; meanwhile, the feed is simple in adding manner, low in cost and remarkable in benefit.

Description

The application of sodium butyrate in ricefield el fodder
Technical field
The present invention relates to a kind of feed addictive, particularly relating to a kind of interpolation in low fish-meal can effectively repair yellow eel Intestinal Morphology, improves the feed addictive of yellow eel intestinal absorption ability, immunity of organisms and growth, belongs to aquatic feeds technical field.
Background technology
Fish meal protein content is high, amino acid balance, palatability are good, ANFs is few, it is most widely used protein sources in aquatic feeds, but in recent years because aquaculture scale is increasing, fish meal annual production declines increasingly, supply falls short of demand to cause fish meal, therefore, the protein sources Peru Fish Dietary seeking high-quality becomes study hotspot.Plant protein source (as dregs of beans) is because price is low, source wide, amino acid comparatively balances, and protein content is higher, is considered to the optimal selection of Peru Fish Dietary, be widely used in aquatic feeds, but, there is a large amount of ANFs in plant protein source, such as soyasaponin, these ANFs can destroy intestinal structure, reduce intestinal absorption ability and immunity, thus affect fish growth, the application of restriction vegetable protein in feed.
Sodium butyrate (n-butyric acie sodium salt, sodium butyrate), be the sodium-salt form of butyric acid, molecular formula is C 4h 7o 2na, molecular weight is 110.09, the sodium butyrate of industrial production is that white is to off-white color, like fine hair shape, its structural formula is as follows, and sodium butyrate has the feature of the very easily moisture absorption, special cheese tapinoma-odour, poor fluidity, be not suitable for feed manufacturing, preserve and apply, the adverse effect of sodium butyrate special odor can be avoided after adopting release-controlled coated technology, improve the mobility of product, and can realize at animal intestinal slow releasing.
  
Sodium butyrate can be dissociated into butyric acid root (C in animal body 4h 7o 2-) and sodium ion (Na +), the further metabolism of liver can be transported to after butyric acid is absorbed by intestinal mucosal epithelial or be used as energy substance by intestinal mucosal epithelial cell and consume, its final metabolite is ketoboidies and carbon dioxide, for intestinal mucosa cells provides the energy of about 75%, sodium butyrate can stimulate the absorption of water and sodium ion in enteron aisle in addition, produce the enzyme promoting Mucous rehabilitation, the simultaneously synthesis of mRNA and protein in irritation cell, improve intestinal villus propagation, increase dark Crypt depth, reduce fine hair width, thus improve body to the abilities of digestive and absorption of nutrient.
At present, sodium butyrate is widely applied as a kind of feed addictive in livestock and poultry, and is not also used widely in aquaculture feed.
Summary of the invention
Technical problem to be solved by this invention is: high for current fish meal prices, under formulation cost pressure, in aquatic feeds, fish meal content reduces, plant protein source uses in a large number and causes intestinal structure to damage, under the background that immunity and growth reduce, sodium butyrate is added in yellow eel feed as a kind of feed addictive, enteron aisle structure can be repaired, strengthen intestinal absorption ability, improve yellow eel growth and immunity, make plant protein source better being utilized in aquatic feeds, thus reduce feed cost.
Technical scheme provided by the invention is: add in yellow eel feed using sodium butyrate as a kind of feed addictive, and addition is that every 1 kilogram of feed adds sodium butyrate 0.5 ~ 1 g.
The present invention also provides a kind of eel feeds, and in this feed, fish meal content is lower than 35%, and plant protein source, higher than 40%, is added with sodium butyrate in this feed, and addition is that every 1 kilogram of feed adds micro-capsule sodium butyrate 0.5 ~ 1 g.
Described eel feeds, in this feed, fish meal content typically refers to fish meal content 25-35% lower than 35%.
Further, described eel feeds, the interpolation of sodium butyrate first mixes with time powder to expand, and then mixes with other raw materials, stir evenly, granulate.
Described sodium butyrate is micro-capsule sodium butyrate.
The present invention provides a kind of eel feeds simultaneously, and containing the fish meal of 32% and 33% dregs of beans in this feed, sodium butyrate addition is that every 1 kilogram of feed adds 0.5 ~ 1 gram of micro-capsule sodium butyrate.
The preparation method of described eel feeds is: described raw material takes by proportioning by (1); (2) the non-powder material in raw material is pulverized; (3) first sodium butyrate is mixed with time powder and expand, then whole raw material mixer is stirred; (4) compound is made according to a conventional method pellet to get product.
The present invention has following beneficial effect:
Feed of the present invention is high mainly for current fish meal prices, formulation cost pressure is large, fish meal content in aquatic feeds is reduced, plant protein source uses in a large number, intestinal structure is caused to damage, under the background that immunity and growth reduce, Intestinal Morphology can be repaired, improve yellow eel intestinal absorption ability and immunity of organisms, promote the growth of yellow eel: (1) can effectively repair yellow eel Intestinal Morphology, strengthen intestinal absorption ability and immunity of organisms, promote yellow eel growth, improve efficiency of feed utilization, improve the application of plant protein source in aquatic feeds, reduce feed cost.(2) addition manner is simple, and expense is low, and benefit is obvious.(3) be specially adapted in current low fish meal, high-vegetable-plant feed formula, Be very effective.
Accompanying drawing explanation
Fig. 1 is yellow eel anterior intestine fluff structures figure, and wherein, A, B are respectively and do not add and add sodium butyrate low fish-meal group yellow eel anterior intestine fluff morphology; C, D are respectively and do not add and add sodium butyrate height fish-meal group yellow eel anterior intestine fluff morphology.
Detailed description of the invention
embodiment 1: sodium butyrate is on yellow eel growth and the impact of blood parameters
Experiment material: micro-capsule sodium butyrate (effective content is generally 30%), commercially available, such as can buy from Hangzhou Kangdequan Feed Co., Ltd.
With reference to yellow eel commercial feed formula, the basal feed that preparation two kinds of fish meal content are different, high fish meal basal feed (42% fish meal) and low fish meal basal feed (32% fish meal), in two kinds of basal feed (see table 1) groups, add 1000mg/kg micro-capsule sodium butyrate respectively, configure the experiment feed that 4 kinds are waited the energy such as nitrogen altogether.
Test is the wild swamp eel of neat specification with swamp eel, net cage domesticating and cultivating is carried out in culture of swamp eel field, Xihu District, Changde City, not bait throwing in material in 2d after yellow eel cartonning, during domestication, the ratio of throwing something and feeding is earthworm and the fresh fish slurry of 1 ︰ 1 first on a small quantity, the ratio of throwing something and feeding of feeding volume and fresh fish slurry is little by little increased according to the situation of ingesting, the fresh fish slurry until yellow eel can ingest completely and 5% of stable its body weight of ingesting after, start to add powdery experimental basis feed (fresh fish Jiang ︰ test feed=4 ︰ 1), the ratio of throwing something and feeding of test feed is increased gradually according to the situation of ingesting, the powdery test feed until yellow eel can ingest completely, specification is selected even after hungry 24h, healthy yellow eel divides into groups.Totally 4 processed group, each processed group establish 3 parallel, totally 12 net cages (1.5m*2.0m*1.0m), 100 tail yellow eels put in a suitable place to breed by every net cage.Throw something and feed with 5% of yellow eel original body mass, throw something and feed day 1 time (17 ︰ 00-18 ︰ 00), test duration 8 weeks.Result of the test is in table 2 and table 3.
Table 1 basal feed composition and component content (% dry weight)
Raw material High fish meal base set Low fish meal base set
Peru's steam fish meal 42 32
Dregs of beans 18 33
Corn protein powder 6 6
FSPC 5 5
Flour 8 2
A-starch 18 18
Fish oil 0 1
Calcium dihydrogen phosphate 1.5 1.5
Choline Chloride 0.5 0.5
Premix 1 1
Mould inhibitor 0.03 0.03
Antioxidant 0.01 0.01
Crude protein 42.6 42.1
Crude fat 6.33 6.03
Coarse ash 10.97 10.56
The impact that sodium butyrate grows swamp eel is added in table 2 feed
Note: indicate in colleague's data different letter for significant difference ( p<0.05), lower same.
  
Table 3 sodium butyrate is to the shadow of swamp eel blood physiological and biochemical indices
Experimental result shows: from table 2 and table 3, sodium butyrate is added in low fish-meal, yellow eel rate of body weight gain improves 15.93%, feed coefficient reduces by 15.74%, and urea nitrogen content reduces by 23.72%, and total protein content improves 56.32%, antalzyme activity improves 36.90%, superoxide dismutase activity improves 32.74%, and superoxide anion resisitance improves 10.30%, but in high fish-meal, adds the above index of sodium butyrate yellow eel do not have marked change.Illustrate in feed that adding sodium butyrate can significantly promote that yellow eel grows, improve efficiency of feed utilization, strengthen yellow eel non-specific immunity, and additive effect is better in low fish-meal.
  
embodiment 2: sodium butyrate is on the impact of swamp eel Intestinal Morphology and absorption function
Experiment feed formula, the grouping of experiment fish and feeding manner are identical with embodiment 1.
Experimental result is shown in Fig. 1, table 4 and table 5.
  
Table 4 sodium butyrate is on the impact of broiler chick before yellow eel
Table 5 sodium butyrate is on the impact of swamp eel intestinal absorption ability
Found out by Fig. 1: A group fine hair is relatively thin, and the accidental enteric epithelium in intestinal villus top comes off, and mucous membrane structure is imperfect, and B group fine hair is sturdy, marshalling, mucomembranous surface striated border clear in structure, intestinal epithelial cell regular shape, closely, dyeing is distinct in arrangement.And C and D enteron aisle fluff morphology does not have notable difference.
As shown in Table 4, add sodium butyrate in low fish-meal and significantly can reduce yellow eel anterior intestine Crypt depth, significantly improve V/C value, and add sodium butyrate in high fish-meal to the not impact of the height of naps of yellow eel anterior intestine, Crypt depth and V/C value.
As known from Table 5, yellow eel enteron aisle Na after adding sodium butyrate in low fish-meal +k +-ATP enzyme vigor improves 22.31%, alkaline phosphatase AKP vigor and improves 127.20%, and in high fish-meal, add sodium butyrate yellow eel enteron aisle Na +k +-ATP enzyme vigor is change no, and alkaline phosphatase AKP vigor reduces on the contrary.
In sum, in low fish-meal, add sodium butyrate can repair yellow eel intestinal structure, improve intestinal absorption ability, and in high fish-meal, add sodium butyrate there is no this effect.

Claims (4)

1. the application of sodium butyrate in preparation yellow eel feed, is characterized in that: in preparation yellow eel feed, add sodium butyrate, and addition is that every 1 kilogram of feed adds sodium butyrate 0.5 ~ 1 g.
2. an eel feeds, is characterized in that: in this feed, fish meal content is lower than 35%, and plant protein source, higher than 40%, is added with sodium butyrate in this feed, and addition is that every 1 kilogram of feed adds sodium butyrate 0.5 ~ 1 g.
3. eel feeds as claimed in claim 2, is characterized in that, the interpolation of sodium butyrate first mixes with time powder to expand, and then mixes with other raw materials, stir evenly, granulate.
4. eel feeds as claimed in claim 2 or claim 3, it is characterized in that, described sodium butyrate is micro-capsule sodium butyrate.
CN201410430326.8A 2014-08-28 2014-08-28 Application of sodium butyrate to feed for rice field eels Pending CN104222534A (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105558425A (en) * 2015-12-24 2016-05-11 南宁学院 Pelteobagrus fulvidraco whitening preventing feed additive and production technology thereof
CN105995192A (en) * 2016-05-17 2016-10-12 长沙学院 Preparation method and application of nanometer sustained release sodium butyrate for feed of grass carp
CN106343249A (en) * 2016-08-23 2017-01-25 四川农业大学 Nutrient formula capable of relieving erucic acid induced fish enteritis, using method, application and feed
CN111511200A (en) * 2017-11-08 2020-08-07 以色列国家农业部、农村发展农业研究组织·沃尔卡尼中心 Compositions and methods for aquaculture

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CN103238730A (en) * 2012-03-22 2013-08-14 杭州康德权饲料有限公司 Preparation method of microencapsulation diolame sodium butyrate
CN103404723A (en) * 2013-07-19 2013-11-27 天门海大饲料有限公司 Puffed floating formula feed special for rice field eels and preparation method thereof
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CN101301030A (en) * 2008-05-22 2008-11-12 新奥(厦门)农牧发展有限公司 Prescription of particles coated by butanoic acid derivative for feeding and preparing technique thereof
CN103238730A (en) * 2012-03-22 2013-08-14 杭州康德权饲料有限公司 Preparation method of microencapsulation diolame sodium butyrate
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Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105558425A (en) * 2015-12-24 2016-05-11 南宁学院 Pelteobagrus fulvidraco whitening preventing feed additive and production technology thereof
CN105995192A (en) * 2016-05-17 2016-10-12 长沙学院 Preparation method and application of nanometer sustained release sodium butyrate for feed of grass carp
CN105995192B (en) * 2016-05-17 2019-05-10 长沙学院 A kind of preparation method and application of feed of grass carp nano controlled-release sodium butyrate
CN106343249A (en) * 2016-08-23 2017-01-25 四川农业大学 Nutrient formula capable of relieving erucic acid induced fish enteritis, using method, application and feed
CN111511200A (en) * 2017-11-08 2020-08-07 以色列国家农业部、农村发展农业研究组织·沃尔卡尼中心 Compositions and methods for aquaculture
CN111511200B (en) * 2017-11-08 2023-11-07 以色列国家农业部、农村发展农业研究组织·沃尔卡尼中心 Compositions and methods for aquaculture
US12016353B2 (en) 2017-11-08 2024-06-25 The State Of Israel, Ministry Of Agriculture & Rural Development, Agricultural Research Organization (Aro) (Volcani Center) Compositions and methods for aquaculturing

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Application publication date: 20141224