CN104212708B - A kind of intestinal contents target component extraction element - Google Patents
A kind of intestinal contents target component extraction element Download PDFInfo
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- CN104212708B CN104212708B CN201410484215.5A CN201410484215A CN104212708B CN 104212708 B CN104212708 B CN 104212708B CN 201410484215 A CN201410484215 A CN 201410484215A CN 104212708 B CN104212708 B CN 104212708B
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- 238000000605 extraction Methods 0.000 title claims abstract description 102
- 210000003736 gastrointestinal content Anatomy 0.000 title claims abstract description 14
- 238000007789 sealing Methods 0.000 claims description 54
- 238000001914 filtration Methods 0.000 claims description 50
- 239000012528 membrane Substances 0.000 claims description 42
- 239000012530 fluid Substances 0.000 claims description 21
- 239000007788 liquid Substances 0.000 claims description 16
- 239000000725 suspension Substances 0.000 abstract description 16
- 230000000694 effects Effects 0.000 abstract description 11
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract description 6
- 201000010099 disease Diseases 0.000 abstract description 5
- 239000000284 extract Substances 0.000 abstract description 4
- 230000009286 beneficial effect Effects 0.000 abstract description 2
- 230000002550 fecal effect Effects 0.000 abstract description 2
- 239000011148 porous material Substances 0.000 description 11
- 239000002689 soil Substances 0.000 description 10
- 239000003085 diluting agent Substances 0.000 description 8
- 241000894006 Bacteria Species 0.000 description 6
- 238000005516 engineering process Methods 0.000 description 5
- 241000168254 Siro Species 0.000 description 4
- 239000008267 milk Substances 0.000 description 4
- 210000004080 milk Anatomy 0.000 description 4
- 235000013336 milk Nutrition 0.000 description 4
- 239000002504 physiological saline solution Substances 0.000 description 4
- 238000009987 spinning Methods 0.000 description 4
- 230000000968 intestinal effect Effects 0.000 description 3
- 230000001225 therapeutic effect Effects 0.000 description 3
- 206010012735 Diarrhoea Diseases 0.000 description 2
- 102000002322 Egg Proteins Human genes 0.000 description 2
- 108010000912 Egg Proteins Proteins 0.000 description 2
- 239000003242 anti bacterial agent Substances 0.000 description 2
- 229940088710 antibiotic agent Drugs 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 235000013305 food Nutrition 0.000 description 2
- 208000015181 infectious disease Diseases 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 210000000056 organ Anatomy 0.000 description 2
- 210000004681 ovum Anatomy 0.000 description 2
- 230000000144 pharmacologic effect Effects 0.000 description 2
- 206010002198 Anaphylactic reaction Diseases 0.000 description 1
- 208000004232 Enteritis Diseases 0.000 description 1
- 208000004930 Fatty Liver Diseases 0.000 description 1
- 206010019708 Hepatic steatosis Diseases 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 208000008589 Obesity Diseases 0.000 description 1
- 230000036783 anaphylactic response Effects 0.000 description 1
- 208000003455 anaphylaxis Diseases 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 208000024732 dysthymic disease Diseases 0.000 description 1
- 230000008030 elimination Effects 0.000 description 1
- 238000003379 elimination reaction Methods 0.000 description 1
- 208000010706 fatty liver disease Diseases 0.000 description 1
- 210000003608 fece Anatomy 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 210000001035 gastrointestinal tract Anatomy 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 230000002757 inflammatory effect Effects 0.000 description 1
- 210000002011 intestinal secretion Anatomy 0.000 description 1
- 210000000936 intestine Anatomy 0.000 description 1
- 208000002551 irritable bowel syndrome Diseases 0.000 description 1
- 210000001630 jejunum Anatomy 0.000 description 1
- 238000002386 leaching Methods 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 244000005706 microflora Species 0.000 description 1
- 235000020824 obesity Nutrition 0.000 description 1
- 244000045947 parasite Species 0.000 description 1
- 230000003071 parasitic effect Effects 0.000 description 1
- 239000006041 probiotic Substances 0.000 description 1
- 230000000529 probiotic effect Effects 0.000 description 1
- 235000018291 probiotics Nutrition 0.000 description 1
- 230000008786 sensory perception of smell Effects 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 231100000240 steatosis hepatitis Toxicity 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 238000002054 transplantation Methods 0.000 description 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
- C12M47/02—Separating microorganisms from the culture medium; Concentration of biomass
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- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Sustainable Development (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Extraction Or Liquid Replacement (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
Abstract
The invention provides a kind of intestinal contents target component extraction element, comprise base, support, the vibrating device be arranged on support, the extraction vessel be flexibly connected with vibrating device and the negative pressure device be connected with extraction vessel.Beneficial effect of the present invention is: the present invention extracts integrated, easy to operate to caprophyl from preparing fecal suspension and is easy to medical worker's acceptance, improves the quality of caprophyl and effect of curing the disease.
Description
Technical field
The present invention relates to a kind of medical extraction element, particularly relate to a kind of intestinal contents target component extraction element.
Background technology
Human gastrointestinal tract content has that swill, flora, parasitic ovum etc. are multiple row composition, there is the body fluid components that intestinal secretion generates, have because a variety of causes enters foreign matter in enteron aisle and liquid, also have by Endoscopic removal but the tumor tissues in small, broken bits of not easily directly taking-up.In clinical and research process, differentiate and obtain the composition of these objects, only have rely on effective apparatus auxiliary separating from.Flora in normal human's enteron aisle to be considered in human body a special organ, and ight soil is transplanted and is considered to a kind of special organ transplantation.The bacterium of enteron aisle is about 1000 to 1050 kinds, and the current mankind to the function of wherein Most bacterial, and according to what mechanism organically work between different bacterium, all it be unclear that.Recently, modern medicine has more and more recognized the vital role of intestinal bacteria in human body, will maintain or rebuild the critical treatment means of human intestinal normal microflora as various diseases.Conventional probiotic bacterium medicine and food, just by one or more bacteriums of enteron aisle, through external special cultivation, are then packed according to certain amount.But, because to include the bacteria's numbers and species of human intestinal in all very limited, so its therapeutic value is also very limited.Recent years, caprophyl is transplanted and is paid attention to gradually, especially for the disease that the infection that the pharmacological agenies such as common antibiotics are invalid is relevant, its therapeutic value seems and particularly payes attention to, especially for the disease that the infection that the pharmacological agenies such as common antibiotics are invalid is relevant, its therapeutic value seems particularly important, such as treats antibiotic-associated diarrhea, intractable inflammatory enteritis, Treatment of Refractory Irritable Bowel Syndrome, immunity relevant intractable diarrhoea, obesity, food anaphylaxis, dysthymia disorders bowel symptoms, fatty liver etc.
Scientific development so far, although had a few studies by intestines mirror, gastroscope nasogastric tube, jejunum pipe, stool suspension or caprophyl suspension are transported in gi tract by capsules etc., realize caprophyl to transplant, but, caprophyl before transplanting extracts to be needed first loose and watery stool to be interpreted into stool suspension, and then suspension is put into filtration unit inner filtration, the parasites such as elimination worm's ovum, the flora only remained with, but no matter medical worker is from vision when preparing stool suspension, sense of smell is still psychological all beyond affordability, and complex operation, want to ensure that the activity of caprophyl must complete leaching process fast, and the extraction element of prior art is difficult to complete in one hour from obtaining the extraction of ight soil to caprophyl, be difficult to the quality guaranteeing caprophyl.
Summary of the invention
The object of the present invention is to provide a kind of from prepare stool suspension to caprophyl extract integrated, easy to operate and be easy to medical worker acceptance intestinal contents target component extraction element.
The present invention is realized by following measure: a kind of intestinal contents target component extraction element, the extraction vessel comprise base, support, setting vibrating device on the bracket, being flexibly connected with described vibrating device and the negative pressure device be connected with described extraction vessel;
Described extraction vessel comprises upper surface and lower surface, described upper surface is provided with the fluid inlet with sealing cover, the liquid outlet that can be connected with described negative pressure device is provided with on the sidewall of extraction vessel described in described lower surface, some levels filtering membrane of reducing step by step of aperture is from top to bottom provided with in described extraction vessel between described fluid inlet and described liquid outlet, have interval between filtering membrane described in adjacent two-stage, described in adjacent two-stage between filtering membrane described extraction vessel sidewall on be provided with drain pipe with sealing cover;
Seal diaphragm is provided with at filtering membrane described in the first step and between described fluid inlet, described seal diaphragm comprises all with upper strata retaining plate and lower floor's portable plate of through hole, described lower floor portable plate be also provided with corresponding with the lead to the hole site of described upper strata retaining plate and can seal the projection of described through hole, the upper surface of described projection is hemisphere face; The sidewall being positioned at described extraction vessel below described seal diaphragm is provided with spacing net, described in described spacing net and the first step, between filtering membrane, has interval;
The central position of described extraction vessel bottom surface is provided with bar shaped projection, the sidewall of described bottom surface is provided with two centrosymmetric restriction protrusion; The central position of the upper surface of described vibrating device is provided with circular concave station, the central position of described circular concave station is provided with bar shaped movable block, the lower surface of described bar shaped movable block is provided with spring, the sidewall of described circular concave station is provided with described restriction protrusion with the use of arc-shaped slot, described arc-shaped slot one end is open, the other end is closed.
Described vibrating device comprises and arranges rotation axis on the bracket, two vibrating bottom plates being symmetricly set on the cam on described rotation axis and can moving up and down along support by bearing.
Two sides that described vibrating bottom plate is relative are provided with roller, and described support is provided with the limit sliding chutes corresponding with described roller; In order to better make described vibrating bottom plate maintenance level move up and down, described roller and described limit sliding chutes can arrange multipair.
The lower surface of described vibrating bottom plate is provided with the U-shaped roller used with described cam engagement.
One end of described rotation axis is passed described support and is provided with handle.
The sealing cover of described extraction vessel is provided with the leachy circular groove of band, in described circular groove, is provided with the air valve cap hinged with described sealing cover.
Wherein, preferably, described extraction vessel also can directly be fixed on described vibrating device; That is: an intestinal contents target component extraction element, the negative pressure device comprising base, support, setting vibrating device on the bracket, be fixed on the extraction vessel on described vibrating device and be connected with described extraction vessel;
Described extraction vessel comprises upper surface and lower surface, described upper surface is provided with the fluid inlet with sealing cover, the liquid outlet that can be connected with described negative pressure device is provided with on the sidewall of extraction vessel described in described lower surface, some levels filtering membrane of reducing step by step of aperture is from top to bottom provided with in described extraction vessel between described fluid inlet and described liquid outlet, have interval between filtering membrane described in adjacent two-stage, described in adjacent two-stage between filtering membrane described extraction vessel sidewall on be provided with drain pipe with sealing cover;
Seal diaphragm is provided with at filtering membrane described in the first step and between described fluid inlet, described seal diaphragm comprises all with upper strata retaining plate and lower floor's portable plate of through hole, described lower floor portable plate be also provided with corresponding with the lead to the hole site of described upper strata retaining plate and can seal the projection of described through hole, the upper surface of described projection is hemisphere face; The sidewall being positioned at described extraction vessel below described seal diaphragm is provided with spacing net, described in described spacing net and the first step, between filtering membrane, has interval.
Described vibrating device comprises and arranges rotation axis on the bracket, two vibrating bottom plates being symmetricly set on the cam on described rotation axis and can moving up and down along support by bearing.
Two sides that described vibrating bottom plate is relative are provided with roller, and described support is provided with the limit sliding chutes corresponding with described roller.
The lower surface of described vibrating bottom plate is provided with the U-shaped roller used with described cam engagement.
One end of described rotation axis is passed described support and is provided with handle.
The sealing cover of described extraction vessel is provided with the leachy circular groove of band, in described circular groove, is provided with the air valve cap hinged with described sealing cover.
Wherein, preferably, a kind of intestinal contents target component extraction element, the negative pressure device comprising extraction vessel and be connected with described extraction vessel;
Described extraction vessel comprises upper surface and lower surface, described upper surface is provided with the fluid inlet with sealing cover, the liquid outlet that can be connected with described negative pressure device is provided with on the sidewall of extraction vessel described in described lower surface, some levels filtering membrane of reducing step by step of aperture is from top to bottom provided with in described extraction vessel between described fluid inlet and described liquid outlet, have interval between filtering membrane described in adjacent two-stage, described in adjacent two-stage between filtering membrane described extraction vessel sidewall on be provided with drain pipe with sealing cover;
Seal diaphragm is provided with at filtering membrane described in the first step and between described fluid inlet, described seal diaphragm comprises all with upper strata retaining plate and lower floor's portable plate of through hole, described lower floor portable plate be also provided with corresponding with the lead to the hole site of described upper strata retaining plate and can seal the projection of described through hole, the upper surface of described projection is hemisphere face; The sidewall being positioned at described extraction vessel below described seal diaphragm is provided with spacing net, described in described spacing net and the first step, between filtering membrane, has interval.
The sealing cover of described extraction vessel is provided with the leachy circular groove of band, in described circular groove, is provided with the air valve cap hinged with described sealing cover.
Beneficial effect of the present invention is: the present invention extracts integrated, easy to operate to caprophyl from preparing fecal suspension and is easy to medical worker's acceptance, improves the quality of caprophyl and effect of curing the disease, during use, extraction vessel is fixed on vibrating device and (aims at the bar shaped movable block of vibrating bottom plate by the bar shaped projection bottom extraction vessel, downward pressing also rotates, restriction protrusion just snaps in arc-shaped slot), extraction vessel is put into by just getting ight soil, and add diluent (as physiological saline or milk etc.), rapidly sealing cover is covered, the now upper strata retaining plate of seal diaphragm and lower floor's portable plate compact siro spinning technology, manual shake vibrating device handle, extraction vessel up-down vibration (now vibrating force is not enough to make lower floor's portable plate depart from upper strata retaining plate) under the drive of vibrating device, ight soil and diluent is made well to be mixed to get stool suspension, again the air valve cap on the sealing cover of extraction vessel is opened, open negative pressure device, now, lower floor's portable plate of seal diaphragm departs from upper strata retaining plate very soon under the effect of negative pressure, and drop on the net spacing, under the effect of negative pressure, stool suspension is step by step through filtering membrane, the filtering membrane of different pore size selected according to demand by filtering membrane, finally obtain the target component wanted, open the sealing cover of drain pipe, by syringe sucking-off target component.
Accompanying drawing explanation
Fig. 1 is the structural representation of the embodiment of the present invention 1.
Fig. 2 is the structural representation of extraction vessel bottom surface in the embodiment of the present invention 1.
Fig. 3 is the structural representation of vibrating bottom plate in the embodiment of the present invention 1.
Fig. 4 is that the A-A of Fig. 3 is to sectional view.
Fig. 5 is the structural representation of the embodiment of the present invention 2.
Fig. 6 is the structural representation of the embodiment of the present invention 3.
Fig. 7 is the structural representation of the sealing cover of drain pipe in embodiment of the present invention 1-3.
Fig. 8 is the structural representation of the sealing cover of extraction vessel upper surface in embodiment of the present invention 1-3.
Wherein, Reference numeral is: 1, base; 2, support; 3, rotation axis; 4, liquid outlet; 5, extraction vessel; 6, the sealing cover of drain pipe; 7, filtering membrane; 8, spacing net; 9, projection; 10, through hole; 11, sealing cover; 12, upper strata retaining plate; 13, lower floor's portable plate; 14, vibrating bottom plate; 15, roller; 16, handle; 17, U-shaped roller; 18, cam; 19, cover core; 20, block a shot; 21, air valve cap; 22, port sealing projection; 23, pore; 24, bar shaped projection; 25, restriction protrusion; 26, bar shaped movable block; 27, arc-shaped slot; 28, circular concave station; 29, spring.
Embodiment
For the technical characterstic of this programme can be clearly demonstrated, below by embodiment, this programme is set forth.
Embodiment 1
See Fig. 1-Fig. 4, Fig. 7 and Fig. 8, the present invention is a kind of intestinal contents target component extraction element, comprise base 1, support 2, be arranged on the vibrating device on support 2, the extraction vessel 5 be flexibly connected with vibrating device and the negative pressure device be connected with extraction vessel 5, extraction vessel 5 comprises upper surface and lower surface, upper surface is provided with the fluid inlet with sealing cover 11, the liquid outlet 4 that can be connected with negative pressure device is provided with on the sidewall of lower surface extraction vessel 5, some levels filtering membrane 7 of reducing step by step of aperture is from top to bottom provided with in extraction vessel 5 between fluid inlet and liquid outlet 4, interval is had between adjacent two-stage filtration film 7, between adjacent two-stage filtration film 7 extraction vessel 5 sidewall on be provided with drain pipe with sealing cover (i.e. the sealing cover 6 of drain pipe), wherein, extraction element 5 can take off from vibrating device, negative pressure device is prior art, does not repeat them here.
Vibrating device comprises the vibrating bottom plate 14 that the rotation axis 3, two that is arranged on support 2 by bearing is symmetricly set on the cam 18 on rotation axis 3 and can moves up and down along support 2; Two sides that vibrating bottom plate 14 is relative are provided with roller 15, and support 2 is provided with the limit sliding chutes corresponding with roller 15; The lower surface of vibrating bottom plate 14 be provided with cam 18 with the use of U-shaped roller 17; One end of rotation axis 3 is passed support 2 and is provided with handle 16.
Seal diaphragm is provided with between first step filtering membrane 7 and fluid inlet, seal diaphragm comprises all with upper strata retaining plate 12 and lower floor's portable plate 13 of through hole 10, lower floor's portable plate 13 be also provided with corresponding with through hole 10 position of upper strata retaining plate 12 and can seal the projection 9 of through hole 10, the upper surface of projection 9 is hemisphere face; The sidewall being positioned at extraction vessel 5 below seal diaphragm is provided with spacing net 8, between spacing net 8 and first step filtering membrane 7, has interval.
The central position of extraction vessel 5 bottom surface is provided with bar shaped projection 24, the sidewall of bottom surface is provided with two centrosymmetric restriction protrusion 25; The central position of vibrating bottom plate 14 is provided with circular concave station 28, the central position of circular concave station 28 is provided with bar shaped movable block 26, the lower surface of bar shaped movable block 26 is provided with spring 29, the sidewall of circular concave station 28 is provided with restriction protrusion 25 with the use of arc-shaped slot 27, arc-shaped slot 27 one end is open, the other end is closed, and namely when rotating extraction vessel 5, restriction protrusion 25 just enters in arc-shaped slot 27, rotate to and to a certain degree stop, now extraction element 5 is connected with vibrating bottom plate 14.
The sealing cover of extraction vessel 5 is provided with the circular groove with pore 23, in circular groove, is provided with the air valve cap 21 hinged with sealing cover, air valve cap 21 is provided with and pore 23 correspondence position port sealing projection 22; Drain pipe is provided with internal thread, and the sealing cover 6 of drain pipe comprises block 20 and cover core 19, cover core 19 is provided with the outside screw used with screw-internal thread fit.
During use, extraction vessel 5 is fixed on vibrating device and (aims at the bar shaped movable block 26 of vibrating bottom plate 14 by the bar shaped projection 24 bottom extraction vessel 5, downward pressing also rotates, restriction protrusion 25 just snaps in arc-shaped slot 27), extraction vessel 5 is put into by just getting ight soil, and add diluent (as physiological saline or milk etc.), rapidly sealing cover 11 is covered, the now upper strata retaining plate 12 of seal diaphragm and lower floor's portable plate 13 compact siro spinning technology, manual shake vibrating device handle 16, extraction vessel 5 up-down vibration (vibrating force of vibrating device is not enough to make lower floor's portable plate 13 depart from upper strata retaining plate 12) under the drive of vibrating device, ight soil and diluent is made well to be mixed to get stool suspension, again the air valve cap 21 on the sealing cover 11 of extraction vessel 5 is opened, open negative pressure device, now, lower floor's portable plate 13 of seal diaphragm departs from upper strata retaining plate 12 very soon under the effect of negative pressure, and drop on spacing net 8, under the effect of negative pressure, stool suspension is step by step through filtering membrane 7, the filtering membrane of different pore size selected according to demand by filtering membrane 7, finally obtain the target component wanted, open the sealing cover 6 of drain pipe, by syringe sucking-off target component.
Embodiment 2
See Fig. 5, Fig. 7 and Fig. 8, the present invention is a kind of intestinal contents target component extraction element, comprise base 1, support 2, be arranged on the vibrating device on support 2, the extraction vessel 5 be fixedly connected with vibrating device and the negative pressure device be connected with extraction vessel 5, extraction vessel 5 comprises upper surface and lower surface, upper surface is provided with the fluid inlet with sealing cover 11, the liquid outlet 4 that can be connected with negative pressure device is provided with on the sidewall of lower surface extraction vessel 5, some levels filtering membrane 7 of reducing step by step of aperture is from top to bottom provided with in extraction vessel 5 between fluid inlet and liquid outlet 4, interval is had between adjacent two-stage filtration film 7, between adjacent two-stage filtration film 7 extraction vessel 5 sidewall on be provided with drain pipe with sealing cover (i.e. the sealing cover 6 of drain pipe), wherein, negative pressure device is prior art, does not repeat them here.
Vibrating device comprises the vibrating bottom plate 14 that the rotation axis 3, two that is arranged on support 2 by bearing is symmetricly set on the cam 18 on rotation axis 3 and can moves up and down along support 2; Two sides that vibrating bottom plate 14 is relative are provided with roller 15, and support 2 is provided with the limit sliding chutes corresponding with roller 15; The lower surface of vibrating bottom plate 14 be provided with cam 18 with the use of U-shaped roller 17; One end of rotation axis 3 is passed support 2 and is provided with handle 16.
Seal diaphragm is provided with between first step filtering membrane 7 and fluid inlet, seal diaphragm comprises all with upper strata retaining plate 12 and lower floor's portable plate 13 of through hole 10, lower floor's portable plate 13 be also provided with corresponding with through hole 10 position of upper strata retaining plate 12 and can seal the projection 9 of through hole 10, the upper surface of projection 9 is hemisphere face; The sidewall being positioned at extraction vessel 5 below seal diaphragm is provided with spacing net 8, between spacing net 8 and first step filtering membrane 7, has interval.
The sealing cover of extraction vessel 5 is provided with the circular groove with pore 23, in circular groove, is provided with the air valve cap 21 hinged with sealing cover, air valve cap 21 is provided with and pore 23 correspondence position port sealing projection 22; Drain pipe is provided with internal thread, and the sealing cover 6 of drain pipe comprises block 20 and cover core 19, cover core 19 is provided with the outside screw used with screw-internal thread fit.
During use, extraction vessel 5 is put into by just getting ight soil, and add diluent (as physiological saline or milk etc.), rapidly sealing cover 11 is covered, the now upper strata retaining plate 12 of seal diaphragm and lower floor's portable plate 13 compact siro spinning technology, manual shake vibrating device handle 16, extraction vessel 5 up-down vibration (vibrating force of vibrating device is not enough to make lower floor's portable plate 13 depart from upper strata retaining plate 12) under the drive of vibrating device, ight soil and diluent is made well to be mixed to get stool suspension, again the air valve cap 21 on the sealing cover 11 of extraction vessel 5 is opened, open negative pressure device, now, lower floor's portable plate 13 of seal diaphragm departs from upper strata retaining plate 12 very soon under the effect of negative pressure, and drop on spacing net 8, under the effect of negative pressure, stool suspension is step by step through filtering membrane 7, the filtering membrane of different pore size selected according to demand by filtering membrane 7, finally obtain the target component wanted, open the sealing cover 6 of drain pipe, by syringe sucking-off target component.
Embodiment 3
See Fig. 6, Fig. 7 and Fig. 8, the present invention is a kind of intestinal contents target component extraction element, the negative pressure device comprising extraction vessel 5 and be connected with extraction vessel 5, extraction vessel 5 comprises upper surface and lower surface, upper surface is provided with the fluid inlet with sealing cover 11, the liquid outlet 4 that can be connected with negative pressure device is provided with on the sidewall of lower surface extraction vessel 5, some levels filtering membrane 7 of reducing step by step of aperture is from top to bottom provided with in extraction vessel 5 between fluid inlet and liquid outlet 4, interval is had between adjacent two-stage filtration film 7, between adjacent two-stage filtration film 7 extraction vessel 5 sidewall on be provided with drain pipe with sealing cover (i.e. the sealing cover 6 of drain pipe), wherein, extraction element 5 can take off from vibrating device, negative pressure device is prior art, does not repeat them here.
Seal diaphragm is provided with between first step filtering membrane 7 and fluid inlet, seal diaphragm comprises all with upper strata retaining plate 12 and lower floor's portable plate 13 of through hole 10, lower floor's portable plate 13 be also provided with corresponding with through hole 10 position of upper strata retaining plate 12 and can seal the projection 9 of through hole 10, the upper surface of projection 9 is hemisphere face; The sidewall being positioned at extraction vessel 5 below seal diaphragm is provided with spacing net 8, between spacing net 8 and first step filtering membrane 7, has interval.
The sealing cover of extraction vessel 5 is provided with the circular groove with pore 23, in circular groove, is provided with the air valve cap 21 hinged with sealing cover, air valve cap 21 is provided with and pore 23 correspondence position port sealing projection 22; Drain pipe is provided with internal thread, and the sealing cover 6 of drain pipe comprises block 20 and cover core 19, cover core 19 is provided with the outside screw used with screw-internal thread fit.
During use, extraction vessel 5 is put into by just getting ight soil, and add diluent (as physiological saline or milk etc.), rapidly sealing cover 11 is covered, the now upper strata retaining plate 12 of seal diaphragm and lower floor's portable plate 13 compact siro spinning technology, the strength of manually rocking extraction vessel 5(hand wobble is not enough to make lower floor's portable plate 13 depart from upper strata retaining plate 12), ight soil and diluent is made well to be mixed to get stool suspension, again the air valve cap 21 on the sealing cover 11 of extraction vessel 5 is opened, open negative pressure device, now, lower floor's portable plate 13 of seal diaphragm departs from upper strata retaining plate 12 very soon under the effect of negative pressure, and drop on spacing net 8, under the effect of negative pressure, stool suspension is step by step through filtering membrane 7, the filtering membrane of different pore size selected according to demand by filtering membrane 7, finally obtain the target component wanted, open the sealing cover 6 of drain pipe, by syringe sucking-off target component.
The foregoing is only preferred embodiment of the present invention, not in order to limit the present invention, within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.
Claims (3)
1. an intestinal contents target component extraction element, is characterized in that, the extraction vessel comprise base, support, setting vibrating device on the bracket, being flexibly connected with described vibrating device and the negative pressure device be connected with described extraction vessel;
Described vibrating device comprises and arranges rotation axis on the bracket, two vibrating bottom plates being symmetricly set on the cam on described rotation axis and can moving up and down along support by bearing;
Described extraction vessel comprises upper surface and lower surface, described upper surface is provided with the fluid inlet with sealing cover, the liquid outlet that can be connected with described negative pressure device is provided with on the sidewall of extraction vessel described in described lower surface, some levels filtering membrane of reducing step by step of aperture is from top to bottom provided with in described extraction vessel between described fluid inlet and described liquid outlet, have interval between filtering membrane described in adjacent two-stage, described in adjacent two-stage between filtering membrane described extraction vessel sidewall on be provided with drain pipe with sealing cover;
Seal diaphragm is provided with at filtering membrane described in the first step and between described fluid inlet, described seal diaphragm comprises all with upper strata retaining plate and lower floor's portable plate of through hole, described lower floor portable plate be also provided with corresponding with the lead to the hole site of described upper strata retaining plate and can seal the projection of described through hole, the upper surface of described projection is hemisphere face; The sidewall being positioned at described extraction vessel below described seal diaphragm is provided with spacing net, described in described spacing net and the first step, between filtering membrane, has interval;
The central position of described extraction vessel bottom surface is provided with bar shaped projection, the sidewall of described bottom surface is provided with two centrosymmetric restriction protrusion; The central position of the upper surface of described vibrating device is provided with circular concave station, the central position of described circular concave station is provided with bar shaped movable block, the lower surface of described bar shaped movable block is provided with spring, the sidewall of described circular concave station is provided with described restriction protrusion with the use of arc-shaped slot, described arc-shaped slot one end is open, the other end is closed;
One end of described rotation axis is passed described support and is provided with handle;
The sealing cover of described extraction vessel is provided with the leachy circular groove of band, in described circular groove, is provided with the air valve cap hinged with described sealing cover.
2. intestinal contents target component extraction element according to claim 1, is characterized in that, two sides that described vibrating bottom plate is relative are provided with roller, and described support is provided with the limit sliding chutes corresponding with described roller.
3. intestinal contents target component extraction element according to claim 1 and 2, is characterized in that, the lower surface of described vibrating bottom plate is provided with the U-shaped roller used with described cam engagement.
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510748036.2A CN105296340B (en) | 2014-09-19 | 2014-09-19 | A kind of intestinal contents fractions extraction element |
| CN201410484215.5A CN104212708B (en) | 2014-09-19 | 2014-09-19 | A kind of intestinal contents target component extraction element |
| CN201510748035.8A CN105287643B (en) | 2014-09-19 | 2014-09-19 | A kind of intestinal contents component extracting |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410484215.5A CN104212708B (en) | 2014-09-19 | 2014-09-19 | A kind of intestinal contents target component extraction element |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
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| CN201510748036.2A Division CN105296340B (en) | 2014-09-19 | 2014-09-19 | A kind of intestinal contents fractions extraction element |
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| CN201510748036.2A Expired - Fee Related CN105296340B (en) | 2014-09-19 | 2014-09-19 | A kind of intestinal contents fractions extraction element |
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| CN104814767A (en) * | 2015-05-20 | 2015-08-05 | 卢士海 | Disposable intestinal content extracting device |
| CN108330057B (en) * | 2016-04-27 | 2021-09-10 | 隋振国 | Intestinal content flora extraction device and extraction method |
| CN105969651A (en) * | 2016-06-16 | 2016-09-28 | 胡俊 | Microorganism oscillating cleaning and recycling system |
| CN106318859B (en) * | 2016-08-22 | 2018-08-31 | 中国人民解放军南京军区南京总医院 | A kind of closed continuous bacterium solution configuration device |
| CN106190793B (en) * | 2016-08-31 | 2018-12-25 | 孟素兰 | A kind of liquid manure Preparation equipment |
| CN106399068B (en) * | 2016-08-31 | 2018-12-25 | 孟素兰 | A kind of device preparing liquid manure manually |
| CN108504540A (en) * | 2018-04-11 | 2018-09-07 | 李长寿 | A kind of low temperature resistant bacterium separator |
| US20210187039A1 (en) * | 2018-08-20 | 2021-06-24 | The Medical Research, Infrastructure and Health Services Fund of the Tel Aviv Medical Center | Fecal processing device and methods |
| CN113956956A (en) * | 2021-08-19 | 2022-01-21 | 王兴旺 | Fermentation vat is collected to marsh gas |
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| DE69833185T2 (en) * | 1997-01-29 | 2006-08-10 | Pall Corp. | FILTRATION ARRANGEMENT |
| CN100507525C (en) * | 2004-04-08 | 2009-07-01 | 广东省微生物研究所 | Rapid microbiological detection and reagent for environmental water body |
| CN1257762C (en) * | 2004-06-29 | 2006-05-31 | 浙江大学 | Preparation method of detection filter membrane used for bacteria and virus sampling in air |
| US20070196820A1 (en) * | 2005-04-05 | 2007-08-23 | Ravi Kapur | Devices and methods for enrichment and alteration of cells and other particles |
| FR2902799B1 (en) * | 2006-06-27 | 2012-10-26 | Millipore Corp | METHOD AND UNIT FOR PREPARING A SAMPLE FOR THE MICROBIOLOGICAL ANALYSIS OF A LIQUID |
| CN100999707A (en) * | 2007-01-05 | 2007-07-18 | 新泰市产品质量监督检验所 | Small vessel cultivating operating apparatus of coil bacillus |
| WO2009149257A1 (en) * | 2008-06-04 | 2009-12-10 | The University Of Chicago | The chemistrode: a plug-based microfluidic device and method for stimulation and sampling with high temporal, spatial, and chemical resolution |
| CN201598287U (en) * | 2010-02-25 | 2010-10-06 | 卢磊 | Bacterium collecting device for laboratory |
| CN201754125U (en) * | 2010-06-12 | 2011-03-02 | 罗进才 | Fecal sample sampling and processing device |
| CN103045713B (en) * | 2013-01-18 | 2015-05-27 | 张帆 | Method for detecting trace amounts of microbes in a liquid sample containing multiple impurities |
| CN203700355U (en) * | 2014-02-13 | 2014-07-09 | 山东省食品药品检验所 | Open type double-filter-membrane filter for microbial limit test of medicines |
| CN204097475U (en) * | 2014-09-19 | 2015-01-14 | 张蓉 | A kind of intestinal contents target component extraction element |
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Also Published As
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| CN105287643B (en) | 2018-11-27 |
| CN105296340A (en) | 2016-02-03 |
| CN105296340B (en) | 2018-03-27 |
| CN105287643A (en) | 2016-02-03 |
| CN104212708A (en) | 2014-12-17 |
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