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CN105287643A - Device for extracting components of intestinal contents - Google Patents

Device for extracting components of intestinal contents Download PDF

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Publication number
CN105287643A
CN105287643A CN 201510748035 CN201510748035A CN105287643A CN 105287643 A CN105287643 A CN 105287643A CN 201510748035 CN201510748035 CN 201510748035 CN 201510748035 A CN201510748035 A CN 201510748035A CN 105287643 A CN105287643 A CN 105287643A
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CN
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device
extraction
support
components
fungi
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CN 201510748035
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Chinese (zh)
Inventor
张蓉
朱婕
刘珊
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济南思拓新源医药科技有限公司
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Abstract

The invention provides a device for extracting components in intestinal contents. The device comprises a base, a support, a vibration device arranged on the support, an extraction container movably connected with the vibration device, and a negative pressure device connected with the extraction container. The device has the advantages of integrating feces suspension preparation and coprophilous fungi extraction, being convenient to operate and capable of being easily accepted by medical staff, and improving coprophilous fungi quality and disease treatment effect.

Description

一种肠道内容物成分提取装置 An infectious contents of the component extracting means

[0001] [0001]

本案为分案申请,原申请的发明名称为:一种肠道内容物目标成分提取装置,原申请的申请日为-2014-09-19,原申请的申请号为:201410484215.5。 Case is a divisional application of parent application entitled: an infectious contents of the target component extracting means to the filing date of the parent application -2014-09-19, the initial application of application number: 201410484215.5.

[0002] [0002]

技术领域 FIELD

[0003] 本发明涉及一种医用提取装置,尤其涉及一种肠道内容物成分提取装置。 [0003] The present invention relates to a medical extraction device, in particular to a component extracting means intestinal contents.

[0004] [0004]

背景技术 Background technique

[0005] 人体胃肠道内容物有食物残渣、菌群、寄生虫卵等多种有行成分,有肠道分泌生成的体液成分,有因为各种原因进入肠道内的异物和液体,还有通过内镜下切除但是不易直接取出的细碎肿瘤组织。 [0005] The human gastrointestinal tract contents of a variety of components with a row of food residues, bacteria, parasite eggs, intestinal secretion has generated a body fluid component, there are various reasons and foreign matter into the liquid in the intestine, as well as by endoscopic resection finely divided but not easily removed tumor tissue directly. 在临床和研究过程中,要分辨和获得这些目的的成分,只有依赖有效的器械辅助分离。 And the clinical course of the study, to identify and obtain the composition of these purposes, and only rely on efficient instrumental separation. 正常人体肠道中的菌群是已经被认为是人体内一个特殊的器官,粪便移植被认为是一种特殊的器官移植。 Normal human intestinal flora is already considered to be a special organ in the human body, fecal transplant is considered to be a special kind of organ transplantation. 肠道的细菌约为1000至1050种,目前人类对其中绝大部分细菌的功能,以及不同细菌之间按照什么机制有机地工作,都尚不清楚。 Intestinal bacteria is about 1000-1050 kinds, current human function for most of the bacteria, and organic work in accordance with what mechanism between different bacteria, it is not clear. 近来,现代医学已经越来越认识到肠道细菌在人体内的重要作用,已经将维持或者重建人体肠道正常菌群作为多种疾病的重要治疗手段。 More recently, modern medicine has increasingly recognized the important role of gut bacteria in the human body, it has been to maintain or re-establish an important treatment of human normal intestinal flora as a variety of diseases. 常用益生菌药物和食物只是将肠道的一种或几种细菌,经过体外专门培养,然后按照一定的量进行包装。 Probiotics and commonly used drugs food just one or several intestinal bacteria, specifically after in vitro culture, and then packaged in a certain amount. 然而,因为所纳入人体肠道的细菌数量和种类都非常有限,所以其治疗价值也很有限。 However, since the number and types of human gut bacteria being incorporated are very limited, so its therapeutic value is limited. 最近几年,粪菌移植已经逐渐得到重视,尤其是对于常用抗生素等药物治疗无效的感染相关的疾病,其治疗价值显得尤为重视,尤其是对于常用抗生素等药物治疗无效的感染相关的疾病,其治疗价值显得尤为重要,比如治疗抗生素相关性腹泻、难治性炎症性肠炎、难治性肠易激综合征、免疫相关难治性腹泻、肥胖、食物过敏、抑郁症肠道症状、脂肪肝等。 In recent years, fecal bacteria transplantation has gradually taken seriously, especially for commonly used antibiotics and other drugs ineffective treatment of infections associated with the disease, its therapeutic value is particularly great importance, especially for antibiotics and other drugs commonly used in therapy of infection-related diseases, which therapeutic value is particularly important, such as the treatment of antibiotic-associated diarrhea, intractable inflammatory bowel disease, irritable bowel syndrome, intractable, immune-related intractable diarrhea, obesity, food allergies, depression, bowel symptoms, fatty liver .

[0006] 科学发展至今,虽然已经有少数研究通过肠镜、胃镜鼻胃管、空肠管、胶囊等将粪便悬浮液或者粪菌悬浮液输送到胃肠道内,实现粪菌移植,但是,移植前的粪菌提取需要先将粪便稀释成粪便悬浮液,然后再将悬浮液放入过滤装置内过滤,滤去虫卵等寄生虫,只保留有用的菌群,但是医务人员在制备粪便悬浮液时无论是从视觉、嗅觉还是心理上都很难接受,而且操作繁琐,想要保证粪菌的活性必须快速完成提取过程,而现有技术的提取装置从取得粪便到粪菌的提取很难在一个小时内完成,很难确保粪菌的质量。 [0006] scientific development so far, although there have been few studies by colonoscopy, gastroscopy nasogastric tube, jejunum tube, capsules or the like stool suspension fecal bacteria suspension delivered into the gastrointestinal tract, achieve fecal bacteria transplantation, however, before transplantation fecal bacteria need to first extract diluted stool to stool suspension, then the suspension was placed in a filter apparatus, filtered eggs and other parasites, retaining only the useful bacteria, but in the manufacture of medical personnel stool suspension whether it is from sight, smell or psychologically difficult to accept, and the operation is complicated, we want to ensure that the activity of fecal bacteria in the extraction process must be done quickly, to extraction prior art devices made from manure to manure bacteria in a difficult within hours to complete, it is difficult to ensure the quality of fecal bacteria.

[0007] [0007]

发明内容 SUMMARY

[0008] 本发明的目的在于提供一种从制备粪便悬浮液到粪菌提取一体化、操作方便和易于医务人员接受的肠道内容物成分提取装置。 [0008] The object of the present invention is to provide an integrated extract prepared from stool suspension to fecal bacteria, easy and convenient operation accepted medical personnel intestinal content component extracting means.

[0009] 本发明是通过如下措施实现的:一种肠道内容物目标成分提取装置,包括底座、支架、设置在所述支架上的振动装置、与所述振动装置活动连接的提取容器和与所述提取容器连接的负压装置; [0009] The present invention is achieved by the following measures: an infectious contents of the target component extracting means includes a vibration means a base, a stent disposed on the bracket, the extraction container is connected to the vibrating means and an active vacuum means connected to the extraction vessel;

所述提取容器包括上端面和下端面,所述上端面设置有带有密封盖的进液口,靠近所述下端面所述提取容器的侧壁上设置有能够与所述负压装置连接的出液口,位于所述进液口和所述出液口之间所述提取容器内设置有若干级由上至下孔径逐级减小的过滤膜,相邻两级所述过滤膜之间有间隔,相邻两级所述过滤膜之间所述提取容器的侧壁上设置有带有密封盖的出液管; The extraction vessel including an upper and lower end faces, the end face is provided with a liquid inlet with the upper seal cover, close to the lower end of the extraction vessel is disposed on a side wall connected to said negative pressure capable device a liquid outlet located between the inlet port and the liquid outlet out of the extraction between the inner container is provided with a filter membrane pore size decreases stepwise from top to bottom several stages of the filter between two adjacent membrane spaced, the two adjacent filter disposed on a side wall of the extraction vessel has a liquid outlet pipe with a sealing cover between the membranes;

位于第一级所述过滤膜与所述进液口之间设置有密封隔板,所述密封隔板包括均带有通孔的上层固定板和下层活动板,所述下层活动板上还设置有与所述上层固定板的通孔位置相对应且能够密封所述通孔的突起,所述突起的上端面为半球面;位于所述密封隔板下方所述提取容器的侧壁上设置有限位网,所述限位网与第一级所述过滤膜之间有间隔;所述提取容器底面的中心位置设置有条形突起,所述底面的侧壁上设置有两个中心对称的限位突起;所述振动装置的上端面的中心位置设置有圆形凹台,所述圆形凹台的中心位置设置有条形活动块,所述条形活动块的下端面设置有弹簧,所述圆形凹台的侧壁上设置有与所述限位突起配合使用的弧形卡槽,所述弧形卡槽一端开放、另一端封闭。 Located at the first stage of the filter into the sealing film and the partition plate disposed between the liquid outlet, said separator comprising a sealing plate and are fixed to the upper movable plate having lower through-hole, the lower movable plate provided there the upper position of the through-hole corresponding to the fixing plate and able to seal the through hole protrusion, said protrusion has a hemispherical upper end; arranged on the side wall located below the extraction vessel sealing diaphragm limited bit network, with a spacing between the network and the limit of the filter in the first stage; the extraction position of the container bottom is provided with strip-shaped central projection is provided with two centrally symmetric limit on the sidewall bottom surface bit projections; disposed on the end face of the center position of the vibrating means sets a circular recess, the center position of the circular recess is provided with a table bar movable block, the lower end surface of the movable block is provided with a strip-shaped spring, the said circular recess is provided on a side wall of the station has a projection with an arcuate slot limiting use, the open end of the arcuate slot, and the other end closed.

[0010] 所述振动装置包括通过轴承设置在所述支架上的转动轴、两个对称设置在所述转动轴上的凸轮和能够沿支架上下运动的振动底板。 [0010] The vibrating means comprises a rotary shaft by a bearing disposed on the bracket, two disposed symmetrically on said rotary shaft and the cam plate can vibrate up and down movement along the support.

[0011] 所述振动底板相对的两个侧面设置有滚轮,所述支架上设置有与所述滚轮相对应的限位滑槽;为了更好的使所述振动底板保持水平上下运动,所述滚轮和所述限位滑槽可以设置多对。 [0011] The vibration plate opposing two sides provided with rollers, said rollers provided with corresponding stop sliding on the bracket; in order to better maintain the level of the vibrating plate moves up and down the rollers and the stopper may be provided a multi-slide pair.

[0012] 所述振动底板的下表面设置有与所述凸轮配合使用的U型滚轮。 The [0012] lower surface of the vibrating plate is provided with a U-shaped roller used in conjunction with the cam.

[0013] 所述转动轴的一端穿过所述支架并设置有手柄。 [0013] One end of the rotary shaft passes through the bracket and is provided with a handle.

[0014] 所述提取容器的密封盖上设置有带有气孔的圆形凹槽,在所述圆形凹槽内设置有与所述密封盖铰接的气阀盖。 [0014] provided with a circular recess having a vent sealing cap of the extraction vessel, the circular recess in the closure is provided with a hinged valve cover.

[0015] [0015]

其中,优选地,所述提取容器也可直接固定在所述振动装置上;即:一种肠道内容物成分提取装置,包括底座、支架、设置在所述支架上的振动装置、固定在所述振动装置上的提取容器和与所述提取容器连接的负压装置; Wherein, preferably, the extraction container may be directly fixed to the vibrating means; i.e.: an infectious contents of the component extracting means includes a vibration means a base, a stent disposed on the support, the fixed said vibrating means on the extraction vessel and the negative pressure device connected to the extraction vessel;

所述提取容器包括上端面和下端面,所述上端面设置有带有密封盖的进液口,靠近所述下端面所述提取容器的侧壁上设置有能够与所述负压装置连接的出液口,位于所述进液口和所述出液口之间所述提取容器内设置有若干级由上至下孔径逐级减小的过滤膜,相邻两级所述过滤膜之间有间隔,相邻两级所述过滤膜之间所述提取容器的侧壁上设置有带有密封盖的出液管; The extraction vessel including an upper and lower end faces, the end face is provided with a liquid inlet with the upper seal cover, close to the lower end of the extraction vessel is disposed on a side wall connected to said negative pressure capable device a liquid outlet located between the inlet port and the liquid outlet out of the extraction between the inner container is provided with a filter membrane pore size decreases stepwise from top to bottom several stages of the filter between two adjacent membrane spaced, the two adjacent filter disposed on a side wall of the extraction vessel has a liquid outlet pipe with a sealing cover between the membranes;

位于第一级所述过滤膜与所述进液口之间设置有密封隔板,所述密封隔板包括均带有通孔的上层固定板和下层活动板,所述下层活动板上还设置有与所述上层固定板的通孔位置相对应且能够密封所述通孔的突起,所述凸起的上端面为半球面;位于所述密封隔板下方所述提取容器的侧壁上设置有限位网,所述限位网与第一级所述过滤膜之间有间隔。 Located at the first stage of the filter into the sealing film and the partition plate disposed between the liquid outlet, said separator comprising a sealing plate and are fixed to the upper movable plate having lower through-hole, the lower movable plate provided there the upper position of the through-hole corresponding to the fixing plate and able to seal the through hole projection, said projection has a hemispherical upper end surface; disposed below the sealing diaphragm is positioned on the side wall of the extraction vessel finite bit network, with a spacing between the network and the limit of the filter in the first stage.

[0016] 所述振动装置包括通过轴承设置在所述支架上的转动轴、两个对称设置在所述转动轴上的凸轮和能够沿支架上下运动的振动底板。 The [0016] apparatus comprising a vibration by a bearing disposed on the rotary shaft of the stent, two disposed symmetrically on said rotary shaft and the cam plate can vibrate up and down movement along the support.

[0017] 所述振动底板相对的两个侧面设置有滚轮,所述支架上设置有与所述滚轮相对应的限位滑槽。 Two sides of the [0017] vibration plate with a roller disposed opposite to said support roller is provided with the corresponding limiting chute.

[0018] 所述振动底板的下表面设置有与所述突轮配合使用的U型滚轮。 [0018] The lower surface of the vibrating plate is provided with a projection to mate with the use of U-wheel roller.

[0019] 所述转动轴的一端穿过所述支架并设置有手柄。 [0019] One end of the rotary shaft passes through the bracket and is provided with a handle.

[0020] 所述提取容器的密封盖上设置有带有气孔的圆形凹槽,在所述圆形凹槽内设置有与所述密封盖铰接的气阀盖。 [0020] provided with a circular recess having a vent sealing cap of the extraction vessel, the circular recess in the closure is provided with a hinged valve cover.

[0021] [0021]

其中,优选地,一种肠道内容物目标成分提取装置,包括提取容器和与所述提取容器连接的负压装置; Wherein, preferably, one intestinal contents target component extracting means includes extracting container and the negative pressure means connected to the extraction vessel;

所述提取容器包括上端面和下端面,所述上端面设置有带有密封盖的进液口,靠近所述下端面所述提取容器的侧壁上设置有能够与所述负压装置连接的出液口,位于所述进液口和所述出液口之间所述提取容器内设置有若干级由上至下孔径逐级减小的过滤膜,相邻两级所述过滤膜之间有间隔,相邻两级所述过滤膜之间所述提取容器的侧壁上设置有带有密封盖的出液管; The extraction vessel including an upper and lower end faces, the end face is provided with a liquid inlet with the upper seal cover, close to the lower end of the extraction vessel is disposed on a side wall connected to said negative pressure capable device a liquid outlet located between the inlet port and the liquid outlet out of the extraction between the inner container is provided with a filter membrane pore size decreases stepwise from top to bottom several stages of the filter between two adjacent membrane spaced, the two adjacent filter disposed on a side wall of the extraction vessel has a liquid outlet pipe with a sealing cover between the membranes;

位于第一级所述过滤膜与所述进液口之间设置有密封隔板,所述密封隔板包括均带有通孔的上层固定板和下层活动板,所述下层活动板上还设置有与所述上层固定板的通孔位置相对应且能够密封所述通孔的突起,所述突起的上端面为半球面;位于所述密封隔板下方所述提取容器的侧壁上设置有限位网,所述限位网与第一级所述过滤膜之间有间隔。 Located at the first stage of the filter into the sealing film and the partition plate disposed between the liquid outlet, said separator comprising a sealing plate and are fixed to the upper movable plate having lower through-hole, the lower movable plate provided there the upper position of the through-hole corresponding to the fixing plate and able to seal the through hole protrusion, said protrusion has a hemispherical upper end; arranged on the side wall located below the extraction vessel sealing diaphragm limited bit network, with a spacing between the network and the limit of the filter in the first stage.

[0022] 所述提取容器的密封盖上设置有带有气孔的圆形凹槽,在所述圆形凹槽内设置有与所述密封盖铰接的气阀盖。 [0022] provided with a circular recess having a vent sealing cap of the extraction vessel, the circular recess in the closure is provided with a hinged valve cover.

[0023] [0023]

本发明的有益效果为:本发明从制备粪便悬液到粪菌提取一体化、操作方便和易于医务人员接受,提高了粪菌的质量和治病效果;使用时,将刚取到粪便放入提取容器中,并加入稀释液(如生理盐水或牛奶等),迅速将密封盖盖上,此时密封隔板的上层固定板与下层活动板紧密连接,手动摇动振动装置手柄,在振动装置的带动下提取容器上下振动(振动装置的振动力量不足以使下层活动板脱离上层固定板),使得粪便与稀释液很好的混合得到粪便悬浮液,再将提取容器的密封盖上的气阀盖打开,开启负压装置,此时,密封隔板的下层活动板在负压的作用下很快脱离上层固定板,并掉落在限位网上,在负压的作用下,粪便悬浮液逐级经过过滤膜,过滤膜根据需求选用不同孔径的过滤膜,最终得到想要的目标成分,打开出液管的密封盖,通过注射器吸出目标 Advantageous effects of the present invention are: the present invention is prepared from a suspension of faecal bacteria to fecal extract integration, ease of operation and readily accepted medical personnel, to improve the quality and the effect of treatment of fecal bacteria; when used, will immediately take the soil in the extraction vessel, and was added diluent (e.g., saline or milk, etc.), will quickly cover the sealing cap, the sealing plate fixing the upper case tightly connected to the lower partition plate movable plate, shaking vibration manual handle means, the vibration device extraction vessel driven by vertical vibration (vibration, vibrating means is not sufficient to lower the movable plate from the upper fixed plate), so that good faeces diluted solution obtained by mixing the stool suspension and then extraction vessel closure cap on the valve cover open, negative pressure device is turned on, at this time, the lower flap seal under the negative pressure in the separator from the upper fixed plate quickly and fall limit line, under the negative pressure, stool suspension stepwise after filtration membrane filtration membrane filtration membrane selection of different pore sizes according to the needs, to give the final desired target component, the sealing cap to open the liquid pipe through a syringe target 分即可。 Points can be.

[0024] [0024]

附图说明 BRIEF DESCRIPTION

[0025] 图1为本发明实施例1的结构示意图。 [0025] Figure 1 schematic structural diagram of an embodiment of the invention.

[0026] 图2为本发明实施例1中提取容器底面的结构示意图。 [0026] In FIG 2 a schematic structure of Example 1 Extraction bottom of the container embodiment of the present invention.

[0027] 图3为本发明实施例1中振动底板的结构示意图。 [0027] FIG. 3 is a schematic structure of a vibration plate according to the present embodiment of the invention.

[0028] 图4为图3的AA向剖面图。 [0028] FIG. 4 is an AA sectional view of FIG. 3 to FIG.

[0029] 图5为本发明实施例2的结构示意图。 [0029] FIG. 5 schematic structural diagram of embodiment 2 of the present invention.

[0030] 图6为本发明实施例3的结构示意图。 [0030] FIG 6 schematic structural diagram of embodiment 3 of the present invention.

[0031] 图7为本发明实施例1-3中出液管的密封盖的结构示意图。 [0031] FIG. 7 1-3 a schematic structural diagram showing the seal cover in the pipette according to embodiments of the present invention.

[0032]图8为本发明实施例1-3中提取容器上端面的密封盖的结构示意图。 [0032] FIG. 8 is a schematic view of the structure of the sealing cap on the end face of the container 1-3 extracts the embodiment of the present invention.

[0033] 其中,附图标记为:1、底座;2、支架;3、转动轴;4、出液口;5、提取容器;6、出液管的密封盖;7、过滤膜;8、限位网;9、突起;10、通孔;11、密封盖;12、上层固定板;13、下层活动板;14、振动底板;15、滚轮;16、手柄;17、U型滚轮;18、凸轮;19、盖芯;20、盖帽;21、气阀盖;22、气孔密封突起;23、气孔;24、条形突起;25、限位突起;26、条形活动块;27、弧形卡槽;28、圆形凹台;29、弹簧。 [0033] wherein reference numerals: 1, a base; 2, stent; 3, the rotary shaft; 4, a liquid outlet; 5, the extraction vessel; 6, a liquid seal cap tube; 7, the filtration membrane; 8, limiting network; 9, protrusions; 10, a through hole; 11, sealing cover; 12, fixed to the upper plate; 13, the lower movable plate; 14, a vibration plate; 15, roller; 16, a handle; 17, U-type rollers; 18 cam; 19, core cover; 20, cap; 21, valve cover; 22, protrusions seal the vents; 23, hole; 24, strip-shaped projections; 25, the stopper projections; 26, strip-shaped movable block; 27, arc shaped slot; 28, circular concave station; 29, a spring.

[0034] [0034]

具体实施方式 detailed description

[0035] 为能清楚说明本方案的技术特点,下面通过具体实施方式,对本方案进行阐述。 [0035] The technical features can clearly illustrate this program, by the following specific embodiments, the present embodiment set forth.

[0036] 实施例1 [0036] Example 1

参见图1-图4、图7和图8,本发明是一种肠道内容物目标成分提取装置,包括底座1、支架2、设置在支架2上的振动装置、与振动装置活动连接的提取容器5和与提取容器5连接的负压装置,提取容器5包括上端面和下端面,上端面设置有带有密封盖11的进液口,靠近下端面提取容器5的侧壁上设置有能够与负压装置连接的出液口4,位于进液口和出液口4之间提取容器5内设置有若干级由上至下孔径逐级减小的过滤膜7,相邻两级过滤膜7之间有间隔,相邻两级过滤膜7之间提取容器5的侧壁上设置有带有密封盖(S卩出液管的密封盖6)的出液管;其中,提取装置5能够从振动装置上取下;负压装置为现有技术,在此不再赘述。 Referring to FIGS. 1-4, 7, and 8, the present invention is an intestinal contents target component extracting means includes a vibration means a base 1, support 2 is provided on the holder 2, the vibrating means connected to the extraction activities 5 with the container and the negative pressure means connected to the extraction vessel 5, the extraction vessel 5 includes an upper and lower end faces, the end faces of the sealing cover is provided with a liquid inlet 11, near the lower end surface is provided on the side wall of the extraction vessel 5 capable the liquid outlet is connected with the negative pressure means 4, located at the inlet and a liquid outlet 4 between the extraction vessel 5 is provided with the filter membrane 7 several stages from top to bottom of the pore is reduced stepwise, two adjacent filter membrane 7 with a spacing between adjacent two filtered extract provided on the side wall of the container having the liquid outlet pipe 5 of the seal cover (S Jie liquid outlet pipe of the sealing cap 6) between the film 7; wherein the extracting means 5 can be removed from the vibrating means; negative pressure device is a prior art, it is not repeated here.

[0037] 振动装置包括通过轴承设置在支架2上的转动轴3、两个对称设置在转动轴3上的凸轮18和能够沿支架2上下运动的振动底板14 ;振动底板14相对的两个侧面设置有滚轮15,支架2上设置有与滚轮15相对应的限位滑槽;振动底板14的下表面设置有与凸轮18配合使用的U型滚轮17 ;转动轴3的一端穿过支架2并设置有手柄16。 [0037] By vibrating means comprises a bearing disposed on the rotary shaft 3 of the bracket 2, two symmetrically arranged on the rotary shaft of the cam 318 and the vibrating plate 2 can be moved up and down along the support 14; 14 of the two opposing sides of the vibration plate is provided with a roller 15, the roller chute provided with a stopper 15 corresponding to the upper bracket 2; a lower surface of the vibration plate 14 is provided with a cam 18 used in conjunction with the U-shaped roller 17; an end of the rotation shaft 3 through the bracket 2 and It is provided with a handle 16.

[0038] 位于第一级过滤膜7与进液口之间设置有密封隔板,密封隔板包括均带有通孔10的上层固定板12和下层活动板13,下层活动板13上还设置有与上层固定板12的通孔10位置相对应且能够密封通孔10的突起9,突起9的上端面为半球面;位于密封隔板下方提取容器5的侧壁上设置有限位网8,限位网8与第一级过滤膜7之间有间隔。 [0038] positioned in the first stage and the filter membrane 7 is provided between the inlet port sealing a separator, the separator comprising a sealing each with through holes 12 of the upper fixing plate 10 and the lower movable plate 13, provided on the lower movable plate 13 and the upper plate 10 has a fixed position corresponding to the through hole 12 and the projection 10 to seal the through hole 9, the projection has a hemispherical end surface 9; extraction separator positioned below the sealing web 8 provided with a limit on the sidewall of the container 5, 8 with a spacing between the stopper and the first stage filter mesh film 7.

[0039] 提取容器5底面的中心位置设置有条形突起24,底面的侧壁上设置有两个中心对称的限位突起25 ;振动底板14的中心位置设置有圆形凹台28,圆形凹台28的中心位置设置有条形活动块26,条形活动块26的下端面设置有弹簧29,圆形凹台28的侧壁上设置有与限位突起25配合使用的弧形卡槽27,弧形卡槽27 —端开放、另一端封闭,即当旋转提取容器5时,限位突起25刚好进入弧形卡槽27内,旋转到一定程度停止,此时提取装置5与振动底板14连接。 [0039] extraction vessel 5 is provided with a bottom surface of the strip center position of the projection 24, provided with two centrally symmetric restraining projections 25 on the bottom surface of the side wall; a central position of the vibration plate 14 is provided with a concave circular table 28, a circular position of the clincher center 28 is provided with a strip-shaped movable block 26, the lower end surface of the bar is provided with a movable block 26 is a spring 29, a circular recess is provided on the side wall 28 of the table has a stopper projection 25 with an arcuate slot for use 27, the arcuate slot 27 - an open end, the other end is closed, i.e. when the rotation of the extraction vessel 5, the stopper projection 25 immediately enters the arcuate slot 27, the rotation is stopped to a certain extent, this time extracting means and the vibration plate 5 14.

[0040] 提取容器5的密封盖上设置有带有气孔23的圆形凹槽,在圆形凹槽内设置有与密封盖铰接的气阀盖21,气阀盖21上设置有与气孔23对应位置气孔密封突起22 ;出液管设置有内螺纹,出液管的密封盖6包括盖帽20和盖芯19,盖芯19上设置有与内螺纹配合使用的外螺纹。 [0040] provided with a hole 23 having a circular groove on the sealing cover extraction vessel 5 is provided with a circular recess in the sealing lid hinged lid and valve 21, the valve 21 is provided on the cover 23 with a hole and the pore-sealing position corresponding to the projection 22; liquid outlet pipe is provided with an internal thread, the sealing cap 6 comprises a liquid pipe cap 19, internal threads mating with external threads for use by core 19 is provided with a core and a cover 20.

[0041] 使用时,将提取容器5固定在振动装置上(即将提取容器5底部的条形突起24对准振动底板14的条形活动块26,向下按压并旋转,限位突起25刚好卡入弧形卡槽27内),将刚取到粪便放入提取容器5中,并加入稀释液(如生理盐水或牛奶等),迅速将密封盖11盖上,此时密封隔板的上层固定板12与下层活动板13紧密连接,手动摇动振动装置手柄16,在振动装置的带动下提取容器5上下振动(振动装置的振动力量不足以使下层活动板13脱离上层固定板12),使得粪便与稀释液很好的混合得到粪便悬浮液,再将提取容器5的密封盖11上的气阀盖21打开,开启负压装置,此时,密封隔板的下层活动板13在负压的作用下很快脱离上层固定板12,并掉落在限位网8上,在负压的作用下,粪便悬浮液逐级经过过滤膜7,过滤膜7根据需求选用不同孔径的过滤膜,最终得到想要的目标成分 [0041] In use, the extraction vessel 5 is fixed to the vibrating means (bottom of the container is about 5 bar to extract the projection 24 bar movable block 14 with the vibrating plate 26 is pressed down and rotated, the stopper protrusion 25 just stuck within the arcuate slot 27), to take just the soil in the extraction vessel 5, and the diluted solution (e.g., saline or milk, etc.), the sealing cover 11 quickly cover, the sealing spacer is fixed upper case and the lower plate 12 is closely connected to the movable plate 13, handle 16 manually shaking vibration apparatus, the extraction vessel 5 vertical vibration driven vibration device (vibrating means vibrating force is insufficient to lower the upper movable plate 13 from the fixed plate 12), such that the stool well mixed with a diluent to give the stool suspension, and then extract the container valve sealing cap 11 on the lid 21 is opened 5, negative pressure device is turned on, at this time, the sealing action of the lower movable plate 13 in the negative pressure separator soon from the upper fixed plate 12, and falls on the stop web 8, under the negative pressure, the stool suspension was filtered through membrane 7 stepwise filtration membrane filtration membrane 7 selected according to the needs of different pore sizes, the finally obtained We want to target components 打开出液管的密封盖6,通过注射器吸出目标成分即可。 A sealing cap to open the liquid pipe 6, through a syringe to the target component.

[0042] [0042]

实施例2 Example 2

参见图5、图7和图8,本发明是一种肠道内容物成分提取装置,包括底座1、支架2、设置在支架2上的振动装置、与振动装置固定连接的提取容器5和与提取容器5连接的负压装置,提取容器5包括上端面和下端面,上端面设置有带有密封盖11的进液口,靠近下端面提取容器5的侧壁上设置有能够与负压装置连接的出液口4,位于进液口和出液口4之间提取容器5内设置有若干级由上至下孔径逐级减小的过滤膜7,相邻两级过滤膜7之间有间隔,相邻两级过滤膜7之间提取容器5的侧壁上设置有带有密封盖(即出液管的密封盖6)的出液管;其中,负压装置为现有技术,在此不再赘述。 Referring to FIG. 5, FIG. 7 and FIG. 8, the present invention is an intestinal content component extracting means includes a vibration means a base 1, support 2 is provided on the holder 2, the extraction vessel and vibrating means 5 and fixedly connected with the vacuum extraction means connected to the container 5, the extraction vessel 5 includes an upper and lower end faces, the end face is provided with a liquid inlet sealing cap 11, near the lower end surface of the extraction vessel 5 is provided on the side wall of the negative pressure means capable of 4 connected to the liquid outlet, the inlet and located in the extraction liquid outlet 4 between the inner container 5 is provided with a filter membrane pore size decreases stepwise from top to bottom several stages 7, there is a filter between the two adjacent film 7 interval, two filtration membrane extract on the side wall of the container 5 is provided with a liquid outlet pipe with a sealing cap (i.e. a liquid seal cover tube 6) between adjacent 7; wherein the negative pressure device is a prior art, this will not be repeated.

[0043] 振动装置包括通过轴承设置在支架2上的转动轴3、两个对称设置在转动轴3上的凸轮18和能够沿支架2上下运动的振动底板14 ;振动底板14相对的两个侧面设置有滚轮15,支架2上设置有与滚轮15相对应的限位滑槽;振动底板14的下表面设置有与凸轮18配合使用的U型滚轮17 ;转动轴3的一端穿过支架2并设置有手柄16。 [0043] By vibrating means comprises a bearing disposed on the rotary shaft 3 of the bracket 2, two symmetrically arranged on the rotary shaft of the cam 318 and the vibrating plate 2 can be moved up and down along the support 14; 14 of the two opposing sides of the vibration plate is provided with a roller 15, the roller chute provided with a stopper 15 corresponding to the upper bracket 2; a lower surface of the vibration plate 14 is provided with a cam 18 used in conjunction with the U-shaped roller 17; an end of the rotation shaft 3 through the bracket 2 and It is provided with a handle 16.

[0044] 位于第一级过滤膜7与进液口之间设置有密封隔板,密封隔板包括均带有通孔10的上层固定板12和下层活动板13,下层活动板13上还设置有与上层固定板12的通孔10位置相对应且能够密封通孔10的突起9,突起9的上端面为半球面;位于密封隔板下方提取容器5的侧壁上设置有限位网8,限位网8与第一级过滤膜7之间有间隔。 [0044] positioned in the first stage and the filter membrane 7 is provided between the inlet port sealing a separator, the separator comprising a sealing each with through holes 12 of the upper fixing plate 10 and the lower movable plate 13, provided on the lower movable plate 13 and the upper plate 10 has a fixed position corresponding to the through hole 12 and the projection 10 to seal the through hole 9, the projection has a hemispherical end surface 9; extraction separator positioned below the sealing web 8 provided with a limit on the sidewall of the container 5, 8 with a spacing between the stopper and the first stage filter mesh film 7.

[0045] 提取容器5的密封盖上设置有带有气孔23的圆形凹槽,在圆形凹槽内设置有与密封盖铰接的气阀盖21,气阀盖21上设置有与气孔23对应位置气孔密封突起22 ;出液管设置有内螺纹,出液管的密封盖6包括盖帽20和盖芯19,盖芯19上设置有与内螺纹配合使用的外螺纹。 [0045] The recess is provided with a circular hole with a sealing cover 23 of the extraction vessel 5 is provided with a circular recess in the sealing lid hinged lid and valve 21, the valve 21 is provided on the cover 23 with a hole and the pore-sealing position corresponding to the projection 22; liquid outlet pipe is provided with an internal thread, the sealing cap 6 comprises a liquid pipe cap 19, internal threads mating with external threads for use by core 19 is provided with a core and a cover 20.

[0046] 使用时,将刚取到粪便放入提取容器5中,并加入稀释液(如生理盐水或牛奶等),迅速将密封盖11盖上,此时密封隔板的上层固定板12与下层活动板13紧密连接,手动摇动振动装置手柄16,在振动装置的带动下提取容器5上下振动(振动装置的振动力量不足以使下层活动板13脱离上层固定板12),使得粪便与稀释液很好的混合得到粪便悬浮液,再将提取容器5的密封盖11上的气阀盖21打开,开启负压装置,此时,密封隔板的下层活动板13在负压的作用下很快脱离上层固定板12,并掉落在限位网8上,在负压的作用下,粪便悬浮液逐级经过过滤膜7,过滤膜7根据需求选用不同孔径的过滤膜,最终得到想要的目标成分,打开出液管的密封盖6,通过注射器吸出目标成分即可。 [0046] In use, the soil in the immediately accessible to extraction vessel 5, and the diluted solution (e.g., saline or milk, etc.), the sealing cover 11 quickly cover, fixing the upper case 12 and the separator plate seal connected to the lower movable plate 13 tightly, shake vibration device manually handle 16, the extraction vessel 5 vertical vibration driven vibration device (vibrating means vibrating force is insufficient to lower the upper movable plate 13 from the fixed plate 12), such that the stool with a diluent well mixed to obtain stool suspension, then extract the container valve sealing cap 11 on the lid 21 is opened 5, negative pressure device is turned on, at this time, the lower flap 13 of the sealing diaphragm quickly under negative pressure from the upper fixed plate 12, and the limit on the net 8 fall, under the influence of negative pressure, the stool suspension was filtered through stepwise membrane 7, selected filter membrane filtration membrane 7 according to the needs of different pore sizes, the finally obtained the desired the target component, the sealing cap to open the liquid pipe 6, through a syringe to the target component.

[0047] 实施例3 [0047] Example 3

参见图6、图7和图8,本发明是一种肠道内容物目标成分提取装置,包括提取容器5和与提取容器5连接的负压装置,提取容器5包括上端面和下端面,上端面设置有带有密封盖11的进液口,靠近下端面提取容器5的侧壁上设置有能够与负压装置连接的出液口4,位于进液口和出液口4之间提取容器5内设置有若干级由上至下孔径逐级减小的过滤膜7,相邻两级过滤膜7之间有间隔,相邻两级过滤膜7之间提取容器5的侧壁上设置有带有密封盖(即出液管的密封盖6)的出液管;其中,提取装置5能够从振动装置上取下;负压装置为现有技术,在此不再赘述。 Referring to FIG. 6, 7 and 8, the present invention is an intestinal contents target component extracting means comprises extracting means 5 and the negative pressure vessel and extraction vessel 5 is connected, the extraction vessel 5 includes an upper and lower end faces, the the end face is provided with a sealing cap having a liquid inlet 11, near the lower end surface of the side wall of the container 5 is provided on the extraction of the liquid outlet connectable with a negative pressure means 4, 4 located between the inlet and a liquid outlet extraction vessel 5 provided with a filter membrane pore size decreases stepwise from top to bottom several stages 7, with a spacing between the adjacent two filter film 7, on the side wall adjacent the extraction vessel 75 between the two membranes is provided with a filter liquid outlet pipe with a sealing cap (i.e. a liquid seal cover tube 6); wherein the extracting means 5 can be removed from the vibrating means; negative pressure device is a prior art, are not repeated here.

[0048] 位于第一级过滤膜7与进液口之间设置有密封隔板,密封隔板包括均带有通孔10的上层固定板12和下层活动板13,下层活动板13上还设置有与上层固定板12的通孔10位置相对应且能够密封通孔10的突起9,突起9的上端面为半球面;位于密封隔板下方提取容器5的侧壁上设置有限位网8,限位网8与第一级过滤膜7之间有间隔。 [0048] positioned in the first stage and the filter membrane 7 is provided between the inlet port sealing a separator, the separator comprising a sealing each with through holes 12 of the upper fixing plate 10 and the lower movable plate 13, provided on the lower movable plate 13 and the upper plate 10 has a fixed position corresponding to the through hole 12 and the projection 10 to seal the through hole 9, the projection has a hemispherical end surface 9; extraction separator positioned below the sealing web 8 provided with a limit on the sidewall of the container 5, 8 with a spacing between the stopper and the first stage filter mesh film 7.

[0049] 提取容器5的密封盖上设置有带有气孔23的圆形凹槽,在圆形凹槽内设置有与密封盖铰接的气阀盖21,气阀盖21上设置有与气孔23对应位置气孔密封突起22 ;出液管设置有内螺纹,出液管的密封盖6包括盖帽20和盖芯19,盖芯19上设置有与内螺纹配合使用的外螺纹。 [0049] The recess is provided with a circular hole with a sealing cover 23 of the extraction vessel 5 is provided with a circular recess in the sealing lid hinged lid and valve 21, the valve 21 is provided on the cover 23 with a hole and the pore-sealing position corresponding to the projection 22; liquid outlet pipe is provided with an internal thread, the sealing cap 6 comprises a liquid pipe cap 19, internal threads mating with external threads for use by core 19 is provided with a core and a cover 20.

[0050] 使用时,将刚取到粪便放入提取容器5中,并加入稀释液(如生理盐水或牛奶等),迅速将密封盖11盖上,此时密封隔板的上层固定板12与下层活动板13紧密连接,手动晃动提取容器5 (手晃动的力量不足以使下层活动板13脱离上层固定板12),使得粪便与稀释液很好的混合得到粪便悬浮液,再将提取容器5的密封盖11上的气阀盖21打开,开启负压装置,此时,密封隔板的下层活动板13在负压的作用下很快脱离上层固定板12,并掉落在限位网8上,在负压的作用下,粪便悬浮液逐级经过过滤膜7,过滤膜7根据需求选用不同孔径的过滤膜,最终得到想要的目标成分,打开出液管的密封盖6,通过注射器吸出目标成分即可。 [0050] In use, the soil in the immediately accessible to extraction vessel 5, and the diluted solution (e.g., saline or milk, etc.), the sealing cover 11 quickly cover, fixing the upper case 12 and the separator plate seal connected to the lower movable plate 13 tightly, the extraction vessel 5 manually shake (hand shake force is not sufficient to lower the upper movable plate 13 from the fixed plate 12), so that good faeces diluted solution obtained by mixing the stool suspension and then the extraction vessel 5 valve 11 on the closure cap lid 21 is opened, negative pressure device is turned on, at this time, the lower flap 13 of the sealing diaphragm in the negative pressure quickly from the upper fixed plate 12, and fall stopper network 8 on under the negative pressure, the stool suspension was filtered through membrane 7 stepwise filtration membrane filtration membrane 7 selected according to the needs of different pore sizes, the ultimate goal to obtain the desired component, the sealing cap to open the liquid pipe 6, via syringe target component can be sucked out.

[0051] [0051]

以上所述仅为本发明的较佳实施例,并不用以限制本发明,凡在本发明的精神和原则之内,所作的任何修改、等同替换、改进等,均应包含在本发明的保护范围之内。 The above are only preferred embodiments of the present invention, not intended to limit the present invention, any modifications within the spirit and principle of the present invention, the, equivalent substitutions, improvements should be included in the protection of the present invention within range.

Claims (6)

  1. 1.一种肠道内容物成分提取装置,包括底座、支架、设置在所述支架上的振动装置、固定在所述振动装置上的提取容器和与所述提取容器连接的负压装置; 所述提取容器包括上端面和下端面,所述上端面设置有带有密封盖的进液口,靠近所述下端面所述提取容器的侧壁上设置有能够与所述负压装置连接的出液口,位于所述进液口和所述出液口之间所述提取容器内设置有若干级由上至下孔径逐级减小的过滤膜,相邻两级所述过滤膜之间有间隔,相邻两级所述过滤膜之间所述提取容器的侧壁上设置有带有密封盖的出液管; 位于第一级所述过滤膜与所述进液口之间设置有密封隔板,所述密封隔板包括均带有通孔的上层固定板和下层活动板,所述下层活动板上还设置有与所述上层固定板的通孔位置相对应且能够密封所述通孔的突起,所述凸起的上端面为半 An intestinal contents component extracting means includes a vibration means a base, a stent disposed on the bracket fixed in the extraction vessel on the vibrating means and the negative pressure device connected to the extraction vessel; the said extraction vessel including an upper and lower end faces, the upper end face is provided with a liquid inlet with a sealing cap, close to the lower end of the extraction vessel are disposed on a sidewall of the connectable with said negative pressure apparatus liquid outlet located in said inlet and said liquid outlet out of the extraction between the inner container is provided with a filter membrane pore size decreases stepwise from top to bottom a plurality of stages, the filter has between two adjacent membrane interval, the two adjacent filter provided on the side wall of the extraction vessel with a liquid outlet pipe between the seal cover film; a filter located between the first stage of the film and the sealing inlet opening a separator, said separator comprising a sealing plate fixing both upper and lower movable plate having a through hole, said lower movable plate provided with a through-hole with the position corresponding to the upper fixed plate and capable of sealing the through- the projection aperture, the upper end surface of boss half 球面;位于所述密封隔板下方所述提取容器的侧壁上设置有限位网,所述限位网与第一级所述过滤膜之间有间隔。 Spherical; provided with a limit on the network side wall located below the extraction vessel sealing diaphragm, with a space between the network and the limit of the filter in the first stage.
  2. 2.根据权利要求1所述的肠道内容物成分提取装置,其特征在于,所述振动装置包括通过轴承设置在所述支架上的转动轴、两个对称设置在所述转动轴上的凸轮和能够沿所述支架上下运动的振动底板。 The composition of the intestinal contents extracting apparatus of claim 1, wherein said vibrating means comprises a rotary shaft by a bearing disposed on the bracket, two symmetrically arranged on the rotating shaft of the cam and along the stent can be moved up and down vibration plate.
  3. 3.根据权利要求1或2所述的肠道内容物成分提取装置,其特征在于,所述振动底板相对的两个侧面设置有滚轮,所述支架上设置有与所述滚轮相对应的限位滑槽。 The intestinal contents or components of the extraction apparatus of claim 1, wherein said vibration plate opposing two sides provided with rollers, said rollers provided with corresponding limits on the bracket bit chute.
  4. 4.根据权利要求1-3任一项所述的肠道内容物成分提取装置,其特征在于,所述振动底板的下表面设置有与所述突轮配合使用的U型滚轮。 The intestinal contents of the components of an extracting apparatus of any one of claims 1-3, characterized in that the lower surface of the vibration plate is provided with a wheel fitted with the U-shaped projections of the roller used.
  5. 5.根据权利要求1-4任一项所述的肠道内容物成分提取装置,其特征在于,所述转动轴的一端穿过所述支架并设置有手柄。 The intestinal contents component according to any one extraction device according to claims 1-4, characterized in that one end of the rotary shaft passes through the bracket and is provided with a handle.
  6. 6.根据权利要求1-5任一项所述的肠道内容物成分提取装置,其特征在于,所述提取容器的密封盖上设置有带有气孔的圆形凹槽,在所述圆形凹槽内设置有与所述密封盖铰接的气阀盖。 The intestinal contents of the components of an extracting apparatus of any one of claims 1 to 5, wherein the extraction vessel is provided with a circular groove on the sealing cover having a vent, said circular the groove is provided with the closure valve hinged lid.
CN 201510748035 2014-09-19 2014-09-19 Device for extracting components of intestinal contents CN105287643A (en)

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CN105969651A (en) * 2016-06-16 2016-09-28 胡俊 Microorganism oscillating cleaning and recycling system
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