CN104211750A - Sterile freeze-drying storage device for cytokines - Google Patents

Sterile freeze-drying storage device for cytokines Download PDF

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Publication number
CN104211750A
CN104211750A CN201310210677.3A CN201310210677A CN104211750A CN 104211750 A CN104211750 A CN 104211750A CN 201310210677 A CN201310210677 A CN 201310210677A CN 104211750 A CN104211750 A CN 104211750A
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CN
China
Prior art keywords
freeze
aseptic
screen cloth
drying
save set
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201310210677.3A
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Chinese (zh)
Inventor
迟令龙
李栋
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SHANDONG QILU STEM CELL ENGINEERING Co Ltd
Original Assignee
SHANDONG QILU STEM CELL ENGINEERING Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SHANDONG QILU STEM CELL ENGINEERING Co Ltd filed Critical SHANDONG QILU STEM CELL ENGINEERING Co Ltd
Priority to CN201310210677.3A priority Critical patent/CN104211750A/en
Publication of CN104211750A publication Critical patent/CN104211750A/en
Pending legal-status Critical Current

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Abstract

The invention relates to a sterile freeze-drying storage device for cytokines. In the prior art, a cytokine product is frozen in a freeze pipe; the freeze pipe is sealed by a sealing film; and then the sealing film is punched manually, so the problems that the cytokine product is contaminated easily and the program is complex are mainly presented. The sterile freeze-drying storage device for the cytokines comprises a pipe cover and a freeze pipe main body connected with the lower end of the pipe cover; the middle part in a cavity in the pipe cover is provided with a sterile screen with the aperture of 0.22 [mu]m; the bottom of the sterile screen is provided with a sterile screen fixing platform; the sterile screen fixing platform is provided with a spiral internal thread; the spiral internal thread is disposed on the lower end of the pipe cover; and a spiral external thread matching with the spiral internal thread is disposed above the freeze pipe main body. The sterile freeze-drying storage device is simple in structure, scientific in design and convenient for use, solves the problem that the cytokines are exposed and contaminated, has a ventilation function, achieves an object of freeze drying during a drying process of the frozen cytokines, and simplifies experimental operation flow.

Description

The aseptic freeze-dried save set of cytokine
Technical field
The present invention relates to a kind of medical test equipment, particularly the aseptic freeze-dried save set of a kind of cytokine.
Background technology
Freeze Drying Technique is the dry product freezed under cryogenic vacuum, and dry rear small product size, shape are substantially constant, in spongy, without drying shrinkage; Original proterties can be reduced into rapidly during rehydration.Freeze Drying Technique can remove the moisture of in material more than 90%, dried product long preservative period, and can be placed in preservation process under room temperature and preserve for a long time in lucifuge or 4 DEG C of refrigerators, does not need expensive cryogenic storage facilities and the preservation condition of complexity; And because its very light weight is convenient to long-distance transport in transportation.
Cytokine lyophilize uses freeze drier to carry out, and dried cytokine needs to dress up with permeable container.When pretreatment mode be cytokine product be put in freezing in freeze pipe after, with sealed membrane sealing, afterwards sealed membrane is manually punchinged, to ensure in drying process, the discharge of freeze-drying transpiring moisture.
Therefore following problem can be run in routine experimentation working process:
1, in experimentation, manual seal, the experimentation such as to punching are easy to microbiological contamination, and program is numerous and diverse.
2, cut a hole pore size and can not control, be easy to expose microbiological contamination, and freeze-drying process volatilization is insufficient, affects freeze-drying efficiency.
Summary of the invention
The technical problem to be solved in the present invention is the above-mentioned defect how overcoming prior art, there is provided a kind of cytokine aseptic freeze-dried save set, the aseptic freeze-dried save set of this cytokine solves cytokine and exposes microbiological contamination problem, can realize cytokine freeze-drying process and carry out in non-Superclean Lab; There is ventilatory function simultaneously, make the frozen cell factor in drying process, reach cryodesiccated object, simplify experimental implementation flow process, greatly save the time of experimental implementation, and convenient to operation.
For solving the problems of the technologies described above, the aseptic freeze-dried save set of this cytokine, comprise the freeze-drying tube body of low temperature resistant pipe lid and pipe connecting lid lower end, the middle portion of pipe lid internal cavities is provided with aseptic screen cloth that is low temperature resistant, that to provide gnotobasis for the freeze drying cell factor, play ventilation effect simultaneously in the process of cell freeze-drying.
Design like this, solves cytokine and exposes microbiological contamination problem, can realize cytokine freeze-drying process and carry out in non-Superclean Lab; There is ventilatory function simultaneously, make the frozen cell factor in drying process, reach cryodesiccated object.
As optimization, the circular bacterium filter screen of aseptic screen cloth to be aperture be 0.22um.Design like this, can realize the gnotobasis in the process of cell freeze-drying, ventilation effect and effect is better.
As optimization, aseptic screen bottom is provided with aseptic screen cloth stationary platform.Design like this, is convenient to fixing aseptic screen cloth.
As optimization, aseptic screen cloth stationary platform has the spiral internal thread for the aseptic screen cloth of fixing seal and connection freeze-drying tube body, and this spiral internal thread is arranged on the lower end of pipe lid.Design like this, is convenient to the aseptic screen cloth of fixing seal and connection freeze-drying tube body.
As optimization, above freeze-drying tube body, be provided with the outer silk of the spiral matched with spiral internal thread.Design like this, is convenient to pipe connecting lid and freeze-drying tube body and sealing effectiveness is better.
As optimization, aseptic screen cloth outer rim is provided with fixing seal bar.Design like this, sealing effectiveness is better.
As optimization, pipe tops is provided with block.Design like this, sealing effectiveness is better.
As optimization, between block and pipe lid, be provided with hinge and snap close.Design like this, is convenient to fixing block and pipe lid and sealing effectiveness is better.
The aseptic freeze-dried save set of cytokine of the present invention, structure is simple, design science, easy to use, solves cytokine and exposes microbiological contamination problem, can realize cytokine freeze-drying process and carry out in non-Superclean Lab; There is ventilatory function simultaneously, make the frozen cell factor in drying process, reach cryodesiccated object, simplify experimental implementation flow process, greatly save the time of experimental implementation.There is good actual application value and promotional value.
Accompanying drawing explanation
Below in conjunction with accompanying drawing, the aseptic freeze-dried save set of this cytokine is described further:
Fig. 1 is the structural representation of the aseptic freeze-dried save set of this cytokine;
Fig. 2 is the structural representation of the aseptic screen cloth of the aseptic freeze-dried save set of this cytokine.
In figure: 1 be aseptic screen cloth for block, 2 be pipe lid, 3,4 be aseptic screen cloth stationary platform, 5 be spiral internal thread, 6 for the outer silk of spiral, 7 be freeze-drying tube body.
Embodiment
For making object of the present invention, technical scheme and advantage clearly understand, to develop simultaneously embodiment referring to accompanying drawing, the present invention is described in more detail.
As shown in Figure 1 and Figure 2, the aseptic freeze-dried save set of this cytokine, comprise the freeze-drying tube body 7 of low temperature resistant pipe lid 2 and pipe connecting lid lower end, the middle portion of pipe lid 2 internal cavities is provided with aseptic screen cloth 3 that is low temperature resistant, that to provide gnotobasis for the freeze drying cell factor, play ventilation effect simultaneously in the process of cell freeze-drying.
Aseptic screen cloth 3 for aperture be the circular bacterium filter screen of 0.22um; Aseptic screen cloth stationary platform 4 is provided with bottom aseptic screen cloth 3; Aseptic screen cloth stationary platform 4 has for the aseptic screen cloth 3 of fixing seal and the spiral internal thread 5 connecting freeze-drying tube body 7, and this spiral internal thread 5 is arranged on the lower end of pipe lid 2.
The outer silk 6 of the spiral matched with spiral internal thread 5 is provided with above freeze-drying tube body 7; Aseptic screen cloth 3 outer rim is provided with fixing seal bar; Pipe lid 2 top is provided with block 1; Hinge and snap close is provided with between block 1 and pipe lid 2.
Above-mentioned embodiment is only concrete case of the present invention; scope of patent protection of the present invention includes but not limited to product form and the style of above-mentioned embodiment; any meet claims of the present invention the aseptic freeze-dried save set of cytokine and any person of an ordinary skill in the technical field to its suitable change done or modification, all should fall into scope of patent protection of the present invention.

Claims (8)

1. the aseptic freeze-dried save set of cytokine, comprise low temperature resistant pipe lid (2) and the freeze-drying tube body (7) of pipe connecting lid lower end, it is characterized in that: the middle portion of described pipe lid (2) internal cavities is provided with aseptic screen cloth (3) that is low temperature resistant, that to provide gnotobasis for the freeze drying cell factor, play ventilation effect simultaneously in the process of cell freeze-drying.
2. the aseptic freeze-dried save set of cytokine according to claim 1, is characterized in that: described aseptic screen cloth (3) for aperture be the circular bacterium filter screen of 0.22um.
3. the aseptic freeze-dried save set of cytokine according to claim 1 and 2, is characterized in that: described aseptic screen cloth (3) bottom is provided with aseptic screen cloth stationary platform (4).
4. the aseptic freeze-dried save set of cytokine according to claim 3, it is characterized in that: described aseptic screen cloth stationary platform (4) has for the aseptic screen cloth of fixing seal (3) and the spiral internal thread (5) connecting freeze-drying tube body (7), and this spiral internal thread (5) is arranged on the lower end of pipe lid (2).
5. the aseptic freeze-dried save set of cytokine according to claim 4, is characterized in that: described freeze-drying tube body (7) top is provided with the outer silk (6) of the spiral matched with spiral internal thread (5).
6. the aseptic freeze-dried save set of cytokine according to claim 5, is characterized in that: described aseptic screen cloth (3) outer rim is provided with fixing seal bar.
7. the aseptic freeze-dried save set of cytokine according to claim 6, is characterized in that: described pipe lid (2) top is provided with block (1).
8. the aseptic freeze-dried save set of cytokine according to claim 7, is characterized in that: be provided with hinge and snap close between described block (1) and pipe lid (2).
CN201310210677.3A 2013-05-31 2013-05-31 Sterile freeze-drying storage device for cytokines Pending CN104211750A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201310210677.3A CN104211750A (en) 2013-05-31 2013-05-31 Sterile freeze-drying storage device for cytokines

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201310210677.3A CN104211750A (en) 2013-05-31 2013-05-31 Sterile freeze-drying storage device for cytokines

Publications (1)

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CN104211750A true CN104211750A (en) 2014-12-17

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104830666A (en) * 2015-06-02 2015-08-12 北京福德安科技有限公司 Anti-pollution PCR (polymerase chain reaction) tube

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100167271A1 (en) * 2008-12-30 2010-07-01 Streck, Inc. Method for screening blood using a preservative that may be in a substantially solid state form
CN201981205U (en) * 2011-01-25 2011-09-21 中国人民解放军第三军医大学第三附属医院 Storage bottle for sterile cell culture medium

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100167271A1 (en) * 2008-12-30 2010-07-01 Streck, Inc. Method for screening blood using a preservative that may be in a substantially solid state form
CN201981205U (en) * 2011-01-25 2011-09-21 中国人民解放军第三军医大学第三附属医院 Storage bottle for sterile cell culture medium

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104830666A (en) * 2015-06-02 2015-08-12 北京福德安科技有限公司 Anti-pollution PCR (polymerase chain reaction) tube

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Application publication date: 20141217

WD01 Invention patent application deemed withdrawn after publication