CN104208343A - Chinese medicine for treating woman metrorrhagia and preparation method thereof - Google Patents
Chinese medicine for treating woman metrorrhagia and preparation method thereof Download PDFInfo
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Abstract
The invention discloses Chinese medicine for treating woman metrorrhagia and a preparation method thereof. The Chinese medicine is prepared from the following raw materials, by weight, of 28-52 parts of ginseng, 27-53 parts of milkvetch roots, 27-53 parts of prepared rehmannia roots, 3-7 parts of triangular-toothed shield herb, 20-30 parts of Chinese angelica, 7-13 parts of donkey-hide gelatin, 3-7 parts of rhizoma cyperi, 3-7 parts of fineleaf schizonepeta herb, 20-30 parts of bighead atractylodes rhizome, 20-30 parts of fructus corni, and 7-13 parts of liquorice roots. According to the Chinese medicine for treating woman metrorrhagia, the raw materials are subjected to decoction, condensation, soaking, drying, and crushing; the Chinese medicine is novel and efficient, free of toxic and side effects, and obvious in treatment effect, medicinal sources are cheap and easy to obtain, and the total curing rate reaches up to 90%.
Description
Technical field
The invention belongs to field of medicaments, especially a kind of Chinese medicine for the treatment of metrorrhagia and preparation method thereof.
Background technology
Metrorrhagia, is also metrorrhagia, metrorrhagia, sudden onset of metrorrhagia, refers to that women is between menstrual period or no longer between menstrual period, bleeds profusely, or the symptom of continuous bleeding, sick when sending out blood flow speed out as tap water, show as bleed too much, overfrequency, long or irregular.But not obvious due to the early symptom of metrorrhagia, be easy to be ignored by people, delay golden hour, bring comparatively major injury to female body.At present, modern medicine not good metrorrhagia treatment way, adopts anti-inflammation hemostasia more, therapy of enriching blood is treated, and as used penicillin, agrimonine, etamsylate etc., cures the symptoms, not the disease, fundamentally can not treat metrorrhagia, effect is not satisfactory, and treatment time is long.What is more, though blood is stopped, the blood stasis stopped is deposited in abdomen and forms enclosed mass, as evacuated enclosed mass in abdomen not in time, is then in peril of one's life, and this is the result that Western medicine therapy is cured the symptoms, not the disease.Therefore, some traditional Chinese medical science are for passing through conditioning health, and the metrorrhagia of dredging the meridian to women is treated.
Summary of the invention
The invention discloses a kind of Chinese medicine for the treatment of metrorrhagia and preparation method thereof, aim to provide a kind of completely newly good to metrorrhagia therapeutic effect, without the medicine of obvious toxic-side effects.
Technical scheme of the present invention is: a kind of Chinese medicine for the treatment of metrorrhagia, the medicament be made up of the raw material of following weight proportioning, Radix Ginseng 28 parts-52 parts, the Radix Astragali 27 parts-53 parts, 27 parts-53 parts, Radix Rehmanniae Preparata, Rhizoma Osmundae ash 3 parts-7 parts, Radix Angelicae Sinensis 20 parts-30 parts, 7 parts-13 parts, Colla Corii Asini, Rhizoma Cyperi 3 parts-7 parts, Herba Schizonepetae 3 parts-7 parts, the Rhizoma Atractylodis Macrocephalae 20 parts-30 parts, Fructus Corni 20 parts-30 parts, 7 parts-13 parts, Radix Glycyrrhizae.
As a kind of preferred implementation, this Chinese medicine is the medicament be made up of the raw material of following weight proportioning, Radix Ginseng 30 parts-50 parts, the Radix Astragali 30 parts-50 parts, 30 parts-50 parts, Radix Rehmanniae Preparata, Rhizoma Osmundae ash 4 parts-6 parts, Radix Angelicae Sinensis 23 parts-27 parts, 9 parts-11 parts, Colla Corii Asini, Rhizoma Cyperi 4 parts-6 parts, Herba Schizonepetae 4 parts-6 parts, the Rhizoma Atractylodis Macrocephalae 23 parts-27 parts, Fructus Corni 23 parts-27 parts, 9 parts-11 parts, Radix Glycyrrhizae.
As a kind of preferred implementation, this Chinese medicine is the medicament be made up of the raw material of following weight proportioning, Radix Ginseng 30 parts-50 parts, the Radix Astragali 30 parts-50 parts, 30 parts-50 parts, Radix Rehmanniae Preparata, Rhizoma Osmundae ash 4 parts-6 parts, Radix Angelicae Sinensis 25 parts, 10 parts, Colla Corii Asini, Rhizoma Cyperi 5 parts, Herba Schizonepetae 5 parts, the Rhizoma Atractylodis Macrocephalae 25 parts, Fructus Corni 25 parts, 10 parts, Radix Glycyrrhizae.
As a kind of preferred implementation, this Chinese medicine is the medicament be made up of the raw material of following weight proportioning, Radix Ginseng 30 parts, the Radix Astragali 30 parts, 30 parts, Radix Rehmanniae Preparata, Rhizoma Osmundae ash 5 parts, Radix Angelicae Sinensis 25 parts, 10 parts, Colla Corii Asini, Rhizoma Cyperi 5 parts, Herba Schizonepetae 5 parts, the Rhizoma Atractylodis Macrocephalae 25 parts, Fructus Corni 25 parts, 10 parts, Radix Glycyrrhizae.
As a kind of preferred implementation, this Chinese medicine is the medicament be made up of the raw material of following weight proportioning, Radix Ginseng 50 parts, the Radix Astragali 50 parts, 50 parts, Radix Rehmanniae Preparata, Rhizoma Osmundae ash 5 parts, Radix Angelicae Sinensis 25 parts, 10 parts, Colla Corii Asini, Rhizoma Cyperi 5 parts, Herba Schizonepetae 5 parts, the Rhizoma Atractylodis Macrocephalae 25 parts, Fructus Corni 25 parts, 10 parts, Radix Glycyrrhizae.
As a kind of preferred implementation, this Chinese medicine is the medicament be made up of the raw material of following weight proportioning, Radix Ginseng 40 parts, the Radix Astragali 40 parts, 40 parts, Radix Rehmanniae Preparata, Rhizoma Osmundae ash 5 parts, Radix Angelicae Sinensis 25 parts, 10 parts, Colla Corii Asini, Rhizoma Cyperi 5 parts, Herba Schizonepetae 5 parts, the Rhizoma Atractylodis Macrocephalae 25 parts, Fructus Corni 25 parts, 10 parts, Radix Glycyrrhizae.
Medicament in above-mentioned embodiment is said dosage form on any one pharmaceutics.
Preferably, described medicament is powder or block agent.
The production method that above-mentioned each component makes medicine of the present invention is: first the Radix Astragali, Radix Rehmanniae Preparata, Rhizoma Osmundae ash, Herba Schizonepetae, the Rhizoma Atractylodis Macrocephalae, Fructus Corni, Radix Glycyrrhizae are mixed by part, repeat 3 times to decoct, add 500 parts of-2000 parts of water to carry out decocting 0.5h-3h at every turn, after the decocting liquid of 3 times is merged, carry out the thick paste liquid filtered, simmer down to relative density is 1.2-2, again Radix Ginseng, Radix Angelicae Sinensis, Colla Corii Asini, Rhizoma Cyperi are put into after above-mentioned thick paste liquid soaks 0.2h-2h, drying, be crushed to granularity and be no more than 500 object Chinese powder medicines.
Certain technique scheme is also direct to be taken by soaking, drying, pulverize the powder obtained, and also in order to taking convenience, then powder can be processed into the forms such as pill, tablet, powder, capsule.
The present invention defers to the compatibility mechanism of monarch, wherein, Radix Ginseng in monarch drug, the Radix Astragali, Radix Rehmanniae Preparata, have that strongly invigorating primordial QI, multiple arteries and veins are admittedly de-, invigorating QI to consolidate the body surface resistance, nourishing YIN and supplementing blood, beneficial essence fill out marrow, the metrostaxis caused metrorrhagia, soreness of the waist and knees, the deficiency of vital energy are weak, the primary symptom such as blood deficiency effectively nursed one's health treatment.Radix Angelicae Sinensis in ministerial drug, the Rhizoma Atractylodis Macrocephalae have enrich blood invigorate blood circulation, regulating menstruation, invigorating the spleen and benefiting QI, dampness diuretic, by the conditioning to liver, the heart, spleen, stomach warp, auxiliary monarch drug strengthens the treatment to metrorrhagia primary symptom.Colla Corii Asini in adjuvant drug, Rhizoma Cyperi, Rhizoma Osmundae ash, Herba Schizonepetae four kinds combination, there is enriching blood, stop blooding, invigorate blood circulation, nourshing Yin and drynsessmoistening prescription, resolving depression of regulating the flow of vital energy, regulating menstruation effect, dredging is strengthened to lung, liver, kidney, tri-jiao channel, effectively assists monarch drug, medicine is treated the dredging of metrorrhagia disease.Radix Glycyrrhizae, because having the effect of coordinating the actions of various ingredients in a prescription, serves as the role making medicine in the present invention, although consumption little can by monarch drug, ministerial drug, make medicine eliminating evil with joint efforts, reach treatment metrorrhagia optimum efficiency.Monarch drug, ministerial drug, adjuvant drug in this Chinese medicine, medicine is cooperatively interacted coordination, mutually support, by the conditioning of the dredging to health meridians, negative and positive deficiency and excess, reach and strengthen patient's autoimmune function, effect of radical cure metrorrhagia.
The Chinese medicine for the treatment of metrorrhagia of the present invention is safe and reliable, good effect, it is the good medicine for the treatment of metrorrhagia, and weak to female body after metrorrhagia, sleepy weak, breathe hard, pulse is thin and delicate etc., and later stage symptom also has good therapeutic effect, have do not perform the operation, taking convenience, short treating period, the advantage such as evident in efficacy.
Detailed description of the invention
Below in conjunction with embodiment, the specific embodiment of the present invention is described in further detail.
Embodiment 1.
A kind of Chinese medicine for the treatment of metrorrhagia, it is the medicament be made up of the raw material of following weight proportioning, Radix Ginseng 30 parts, the Radix Astragali 30 parts, 30 parts, Radix Rehmanniae Preparata, Rhizoma Osmundae ash 5 parts, Radix Angelicae Sinensis 25 parts, 10 parts, Colla Corii Asini, Rhizoma Cyperi 5 parts, Herba Schizonepetae 5 parts, the Rhizoma Atractylodis Macrocephalae 25 parts, Fructus Corni 25 parts, 10 parts, Radix Glycyrrhizae, by the Radix Astragali, Radix Rehmanniae Preparata, Rhizoma Osmundae ash, Herba Schizonepetae, the Rhizoma Atractylodis Macrocephalae, Fructus Corni, Radix Glycyrrhizae is mixed in proportion, repeat 3 times to decoct, add 1000 parts of water to carry out decocting 1h at every turn, after the decocting liquid of 3 times is merged, filter, simmer down to relative density is the thick paste liquid of 1.6, again by Radix Ginseng, Radix Angelicae Sinensis, Colla Corii Asini, Rhizoma Cyperi is put into after above-mentioned thick paste liquid soaks 0.3h, drying, being crushed to granularity is 300 object Chinese powder medicines, make capsule.
Embodiment 2.
A kind of Chinese medicine for the treatment of metrorrhagia, it is the medicament be made up of the raw material of following weight proportioning, Radix Ginseng 50 parts, the Radix Astragali 50 parts, 50 parts, Radix Rehmanniae Preparata, Rhizoma Osmundae ash 5 parts, Radix Angelicae Sinensis 25 parts, 10 parts, Colla Corii Asini, Rhizoma Cyperi 5 parts, Herba Schizonepetae 5 parts, the Rhizoma Atractylodis Macrocephalae 25 parts, Fructus Corni 25 parts, 10 parts, Radix Glycyrrhizae, by the Radix Astragali, Radix Rehmanniae Preparata, Rhizoma Osmundae ash, Herba Schizonepetae, the Rhizoma Atractylodis Macrocephalae, Fructus Corni, Radix Glycyrrhizae is mixed in proportion, repeat 3 times to decoct, add 1000 parts of water to carry out decocting 1h at every turn, after the decocting liquid of 3 times is merged, filter, simmer down to relative density is the thick paste liquid of 1.4, again by Radix Ginseng, Radix Angelicae Sinensis, Colla Corii Asini, Rhizoma Cyperi is put into after above-mentioned thick paste liquid soaks 0.4h, drying, being crushed to granularity is 400 object Chinese powder medicines, make tablet.
Embodiment 3.
A kind of Chinese medicine for the treatment of metrorrhagia, it is the medicament be made up of the raw material of following weight proportioning, Radix Ginseng 40 parts, the Radix Astragali 40 parts, 40 parts, Radix Rehmanniae Preparata, Rhizoma Osmundae ash 5 parts, Radix Angelicae Sinensis 25 parts, 10 parts, Colla Corii Asini, Rhizoma Cyperi 5 parts, Herba Schizonepetae 5 parts, the Rhizoma Atractylodis Macrocephalae 25 parts, Fructus Corni 25 parts, 10 parts, Radix Glycyrrhizae, by the Radix Astragali, Radix Rehmanniae Preparata, Rhizoma Osmundae ash, Herba Schizonepetae, the Rhizoma Atractylodis Macrocephalae, Fructus Corni, Radix Glycyrrhizae is mixed in proportion, repeat 3 times to decoct, add 1000 parts of water to carry out decocting 1h at every turn, after the decocting liquid of 3 times is merged, filter, simmer down to thick paste liquid, again by Radix Ginseng, Radix Angelicae Sinensis, Colla Corii Asini, Rhizoma Cyperi is put into after above-mentioned thick paste liquid soaks 0.3h-1h, drying, be crushed to granularity 250 object Chinese powder medicine, make pill.
1. case-data.
Observe case totally 90 examples, patient is outpatient service and the admissions office patient of certain academy of traditional Chinese medicine, and single-blind randomized is divided into treatment group and matched group 2 groups, often organizes each 30 examples.In age 25-60 year in treatment group 1, the mean age is 42.5 years old, the course of disease 3 days-2 months, average 10 days; In age 26-59 year in treatment group 2, the mean age is 42.7 years old, the course of disease 3 days-2 months, average 9.8 days; In age 24-62 year in matched group, the mean age is 43.2 years old, the course of disease 3 days-2 months, average 9.5.Three groups are compared at age, the course of disease, coincident with severity degree of condition and accompanying diseases etc., and no significant difference (P >=0.05), has comparability.
2. Therapeutic Method.
2.1 matched groups give western medicine routine treatment, and because metrorrhagia is many because having inflammation in body, bleed profusely and ischemia in body during metrorrhagia, therefore adopt anti-inflammation hemostasia, therapy of enriching blood is treated, and uses the Western medicine such as penicillin, agrimonine, etamsylate.
2.2 treatment groups 1 give tcm therapy, take medicament of the present invention, 3 times on the one, a 2-5 grain, 3 days is a course for the treatment of, takes and can take effect 1-9 the course for the treatment of, and consumption can make the appropriate adjustments according to patient age, body weight, the type and the order of severity etc. of disease for the treatment of.
2.3 treatment groups 2 give integrative medicine therapy, matched group basis coordinates and takes medicament of the present invention, 3 times on the one, a 2-5 grain, it within 3 days, is a course for the treatment of, take and can take effect 1-9 the course for the treatment of, consumption can make the appropriate adjustments according to patient age, body weight, the type and the order of severity etc. of disease for the treatment of.
3 curative effect index and safety indexes.
3.1 curative effect index: " the Chinese medical disease Standardization of diagnosis and curative effect " promulgated for 2012 with reference to State Administration of Traditional Chinese Medicine determines following standard: hemorrhage suddenly, blood goes out dripping urine endlessly, and color purple secretly accompanies stasis of blood block, two association's distending pains, lower abdomen pain with tenderness, pale complexion, sleepy weak, breathe hard, corpulent tongue is tender has tooth to print, thin fur moistens, and blood stasis point is seen on the tip of the tongue limit, thready and weak pulse or onion or heavyly alleviate as effectively; All with cardinal symptom: hemorrhage suddenly, blood goes out dripping urine endlessly, color purple secretly accompanies stasis of blood block, two association's distending pains, lower abdomen pain with tenderness, pale complexion, sleepy weak, breathe hard, corpulent tongue is tender has tooth to print, and thin fur moistens, and blood stasis point is seen on the tip of the tongue limit, and thready and weak pulse or onion or disappearance completely of sinking are recovery from illness.
3.2 safety indexes: general health check-up project (body temperature, breathing, pulse, blood pressure), hematuria stool routine, darling renal function inspection etc., to begin a project all before medication and terminate rear each inspection each course for the treatment of once, observe untoward reaction at any time.
4 therapeutic outcomes.
4.1 3 groups of patient's comparitive study, in table 1.
As seen from Table 1, in the routine patient of matched group 30, cure 6 examples, effective 11 examples, invalid 13 examples, total effective rate is 56.7%; In treatment group 1 30 routine patients, cure 18 examples, effective 9 examples, invalid 3 examples, and total effective rate is 90%; In treatment group 2 30 routine patients, cure 18 examples, effective 10 examples, and invalid 2 examples, total effective rate is 93.3%.
Table 1 three groups of patient's comparitive study.
| Group | Cure | Effectively | Invalid | Total effective rate |
| Matched group (30) | 6 | 11 | 13 | 56.7% |
| Treatment group 1(30) | 18 | 9 | 3 | 90% |
| Treatment group 2(30) | 18 | 10 | 2 | 93.3% |
4.2 safety indexes are observed.
Before and after this clinical observation treatment, three groups of general health check-up projects of patient, the inspection of hematuria stool routine, cardiac inspections etc. have no significant change.Viewing duration, three groups there is not serious adverse events during this clinical observation, and before and after three groups of treatments, hepatic and renal function and routine blood test index of correlation are all without significant difference.
Visible, Chinese drugs agentia of the present invention has better curative effect than Western medicine in metrorrhagia, and the advantage especially than Western medicine in healing is more outstanding; Take merely Chinese drugs agentia of the present invention, or Chinese drugs agentia coordinates with Western medicine and takes the therapeutic effect of metrorrhagia aspect all very remarkable, and Integrated TCM is not obvious than the advantage of simple Chinese medicine.
Claims (9)
1. treat the Chinese medicine of metrorrhagia for one kind, it is characterized in that: be the medicament be made up of the raw material of following weight proportioning, Radix Ginseng 28 parts-52 parts, the Radix Astragali 27 parts-53 parts, 27 parts-53 parts, Radix Rehmanniae Preparata, Rhizoma Osmundae ash 3 parts-7 parts, Radix Angelicae Sinensis 20 parts-30 parts, 7 parts-13 parts, Colla Corii Asini, Rhizoma Cyperi 3 parts-7 parts, Herba Schizonepetae 3 parts-7 parts, the Rhizoma Atractylodis Macrocephalae 20 parts-30 parts, Fructus Corni 20 parts-30 parts, 7 parts-13 parts, Radix Glycyrrhizae.
2. the Chinese medicine for the treatment of metrorrhagia as claimed in claim 1, it is characterized in that: be the medicament be made up of the raw material of following weight proportioning, Radix Ginseng 30 parts-50 parts, the Radix Astragali 30 parts-50 parts, 30 parts-50 parts, Radix Rehmanniae Preparata, Rhizoma Osmundae ash 4 parts-6 parts, Radix Angelicae Sinensis 23 parts-27 parts, 9 parts-11 parts, Colla Corii Asini, Rhizoma Cyperi 4 parts-6 parts, Herba Schizonepetae 4 parts-6 parts, the Rhizoma Atractylodis Macrocephalae 23 parts-27 parts, Fructus Corni 23 parts-27 parts, 9 parts-11 parts, Radix Glycyrrhizae.
3. the Chinese medicine for the treatment of metrorrhagia as claimed in claim 1, it is characterized in that: be the medicament be made up of the raw material of following weight proportioning, Radix Ginseng 30 parts-50 parts, the Radix Astragali 30 parts-50 parts, 30 parts-50 parts, Radix Rehmanniae Preparata, Rhizoma Osmundae ash 4 parts-6 parts, Radix Angelicae Sinensis 25 parts, 10 parts, Colla Corii Asini, Rhizoma Cyperi 5 parts, Herba Schizonepetae 5 parts, the Rhizoma Atractylodis Macrocephalae 25 parts, Fructus Corni 25 parts, 10 parts, Radix Glycyrrhizae.
4. the Chinese medicine for the treatment of metrorrhagia as claimed in claim 1, it is characterized in that: be the medicament be made up of the raw material of following weight proportioning, Radix Ginseng 30 parts, the Radix Astragali 30 parts, 30 parts, Radix Rehmanniae Preparata, Rhizoma Osmundae ash 5 parts, Radix Angelicae Sinensis 25 parts, 10 parts, Colla Corii Asini, Rhizoma Cyperi 5 parts, Herba Schizonepetae 5 parts, the Rhizoma Atractylodis Macrocephalae 25 parts, Fructus Corni 25 parts, 10 parts, Radix Glycyrrhizae.
5. the Chinese medicine for the treatment of metrorrhagia as claimed in claim 1, it is characterized in that: be the medicament be made up of the raw material of following weight proportioning, Radix Ginseng 50 parts, the Radix Astragali 50 parts, 50 parts, Radix Rehmanniae Preparata, Rhizoma Osmundae ash 5 parts, Radix Angelicae Sinensis 25 parts, 10 parts, Colla Corii Asini, Rhizoma Cyperi 5 parts, Herba Schizonepetae 5 parts, the Rhizoma Atractylodis Macrocephalae 25 parts, Fructus Corni 25 parts, 10 parts, Radix Glycyrrhizae.
6. the Chinese medicine for the treatment of metrorrhagia as claimed in claim 1, it is characterized in that: be the medicament be made up of the raw material of following weight proportioning, Radix Ginseng 40 parts, the Radix Astragali 40 parts, 40 parts, Radix Rehmanniae Preparata, Rhizoma Osmundae ash 5 parts, Radix Angelicae Sinensis 25 parts, 10 parts, Colla Corii Asini, Rhizoma Cyperi 5 parts, Herba Schizonepetae 5 parts, the Rhizoma Atractylodis Macrocephalae 25 parts, Fructus Corni 25 parts, 10 parts, Radix Glycyrrhizae.
7. the Chinese medicine of the treatment metrorrhagia as described in claim arbitrary in claim 1-6, is characterized in that: the medicament of described medicament is said dosage form on any one pharmaceutics.
8. the Chinese medicine for the treatment of metrorrhagia as claimed in claim 7, is characterized in that: described medicament is powder or block agent.
9. described in claim 8, treat the preparation method of the Chinese medicine of metrorrhagia, it is characterized in that: first the Radix Astragali, Radix Rehmanniae Preparata, Rhizoma Osmundae ash, Herba Schizonepetae, the Rhizoma Atractylodis Macrocephalae, Fructus Corni, Radix Glycyrrhizae are mixed by part, repeat 3 times to decoct, add 500 parts of-2000 parts of water to carry out decocting 0.5h-3h at every turn, after the decocting liquid of 3 times is merged, carry out the thick paste liquid filtered, simmer down to relative density is 1.2-2, again Radix Ginseng, Radix Angelicae Sinensis, Colla Corii Asini, Rhizoma Cyperi are put into after above-mentioned thick paste liquid soaks 0.2h-2h, drying, be crushed to granularity and be no more than 500 object Chinese powder medicines.
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| CN103721198A (en) * | 2012-10-11 | 2014-04-16 | 贠钦亮 | Traditional Chinese medicine pill for treating flooding |
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|---|---|---|---|---|
| CN101439123A (en) * | 2007-11-23 | 2009-05-27 | 曾雄辉 | Method for preparing formulation containing four ingredients |
| CN101810798A (en) * | 2010-05-26 | 2010-08-25 | 泰一和浦（北京）中医药研究院有限公司 | Chinese medicinal composition for treating metrorrhagia and metrostaxis and preparation method thereof |
| CN103721198A (en) * | 2012-10-11 | 2014-04-16 | 贠钦亮 | Traditional Chinese medicine pill for treating flooding |
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Application publication date: 20141217 |