CN104189397A - Anti-inflammatory tincture and preparing method thereof - Google Patents
Anti-inflammatory tincture and preparing method thereof Download PDFInfo
- Publication number
- CN104189397A CN104189397A CN201410463501.3A CN201410463501A CN104189397A CN 104189397 A CN104189397 A CN 104189397A CN 201410463501 A CN201410463501 A CN 201410463501A CN 104189397 A CN104189397 A CN 104189397A
- Authority
- CN
- China
- Prior art keywords
- radix
- parts
- tincture
- rhizoma
- ethanol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Abstract
The invention relates to an anti-inflammatory tincture and a preparing method thereof and belongs to the technical field of Chinese medicine. The anti-inflammatory tincture comprises the following ingredients in a part by weight: 22-26 parts of rhizoma paridis, 32-34 parts of rhubarb, 4-5 parts of safflower, 7-10 parts of radix angelicae dahuricae, 15-18 parts of giant knotweed rhizome, 7-9 parts of arnebia euchroma, 7-9 parts of radix aconiti agrestis, 11-14 parts of psammosilene tunicoides, 2-3 parts of semen strychni, 16-18 parts of arisaema aridum, 16-18 parts of radix sophorae flavescentis, 15-18 parts of salvia miltiorrhiza and 4-7 parts of short-pedicel aconite root. The preparing method of the anti-inflammatory tincture is simple. The prepared anti-inflammatory tincture has great effects of clearing internal heat, dispelling humidity, purging pathogenic fire, relieving toxins, promoting blood circulation, dissolving stasis, reducing swellings, alleviating pain, relieving inflammations and discharging pus.
Description
Technical field
The invention belongs to technical field of Chinese medicines, be specifically related to scorching tincture and preparation method thereof.
Background technology
On existing market, there is promoting blood circulation to remove blood stasis, although the external used medicine of reducing swelling and alleviating pain effect is a lot, but their function is comparatively limited, as Yunnan Baiyao aerosol, although there is promoting blood circulation to remove blood stasis, reducing swelling and alleviating pain effect, for traumatic injury, swelling and pain due to blood stasis, muscular soreness and rheumatalgia, but cannot be used for trauma infection contamination, carbuncle, furuncle, mosquito bite, itchy skin eruption, there is limitation.
The existing medicine for itchy skin eruption mostly is western medicine composition as antiallergic class, hormones class on the market at present, and its side effect is large.Therefore how overcoming the deficiencies in the prior art is problems that current technical field of Chinese medicines is needed solution badly.
Summary of the invention
The object of the invention is, in order to solve the deficiencies in the prior art, provides one to remove scorching tincture and preparation method thereof.This goes the preparation method of scorching tincture simple, and the scorching tincture that goes making has good removing damp-heat, eliminating fire and detoxication, and blood circulation promoting and blood stasis dispelling, the effect of reducing swelling and alleviating pain and antiinflammatory evacuation of pus, can be used for traumatic injury, trauma infection contamination, carbuncle, furuncle, mosquito bite, itchy skin eruption.Compared with prior art, removing scorching tincture is pure Chinese medicinal preparation, and side effect is little, and production technology is easy, cheap.
The technical solution used in the present invention is as follows:
Remove scorching tincture, comprise the following component according to parts by weight meter: Rhizoma Paridis 22-26 part, Radix Et Rhizoma Rhei 32-34 part, Flos Carthami 4-5 part, Radix Angelicae Dahuricae 7-10 part, Rhizoma Polygoni Cuspidati 15-18 part, Radix Arnebiae (Radix Lithospermi) 7-9 part, Radix Aconiti Kusnezoffii 7-9 part, RADIX PSAMMOSILENE 11-14 part, Semen Strychni 2-3 part, Rhizoma Arisaematis 16-18 part, Radix Sophorae Flavescentis 16-18 part, Radix Salviae Miltiorrhizae 15-18 part, Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) 4-7 part.
Further, preferably describedly remove scorching tincture, comprise the following component according to parts by weight meter: 25 parts of Rhizoma Paridis, 33.3 parts of Radix Et Rhizoma Rhei, 4.2 parts, Flos Carthami, 8.4 parts of the Radixs Angelicae Dahuricae, 16.7 parts of Rhizoma Polygoni Cuspidati, 8.4 parts of Radix Arnebiae (Radix Lithospermi)s, 8.4 parts of Radix Aconiti Kusnezoffii, 12.5 parts of RADIX PSAMMOSILENEs, 2.5 parts of Semen Strychni, 16.7 parts of Rhizoma Arisaematis, 16.7 parts of Radix Sophorae Flavescentiss, 16.7 parts of Radix Salviae Miltiorrhizaes, 5.8 parts of Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani)s.
The present invention also provides a kind of preparation method of removing scorching tincture, comprises the steps:
Step (1) is ground into coarse powder by Rhizoma Paridis, Radix Et Rhizoma Rhei, Flos Carthami, the Radix Angelicae Dahuricae, Rhizoma Polygoni Cuspidati, Radix Arnebiae (Radix Lithospermi), Radix Aconiti Kusnezoffii, RADIX PSAMMOSILENE, Semen Strychni, Rhizoma Arisaematis, Radix Sophorae Flavescentis, Radix Salviae Miltiorrhizae together with Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani);
Step (2), makes solvent with 62-68% ethanol, and the coarse powder dipping that step (1) is obtained spends the night, and is then added in percolator, then adds 62-68% ethanol to liquid level to exceed medical material surface, places 20-26 hour;
Step (3), after step (2) is placed, carries out percolation extraction using ethanol as leaching solvent, and regulating extracting solution is 55-65% containing alcohol amount, leaves standstill, and to obtain final product.
Further, preferably in described step (3) using 63% ethanol as leaching solvent.
Further, preferably time of repose is 12-24h in described step (3).
Further, preferably the described preparation method of removing scorching tincture, comprises the steps:
Step (1) is ground into coarse powder by Rhizoma Paridis, Radix Et Rhizoma Rhei, Flos Carthami, the Radix Angelicae Dahuricae, Rhizoma Polygoni Cuspidati, Radix Arnebiae (Radix Lithospermi), Radix Aconiti Kusnezoffii, RADIX PSAMMOSILENE, Semen Strychni, Rhizoma Arisaematis, Radix Sophorae Flavescentis, Radix Salviae Miltiorrhizae together with Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani);
Step (2), makes solvent with 65% ethanol, and the coarse powder dipping that step (1) is obtained spends the night, and is then added in percolator, then adds 65% ethanol to liquid level to exceed medical material surface, places 24 hours;
Step (3), after step (2) is placed, carries out percolation extraction using ethanol as leaching solvent, and regulating extracting solution is 55-65% containing alcohol amount, leaves standstill, and to obtain final product.
product composition of the present invention is differentiated:
(1) get product 20ml of the present invention, evaporate to dryness, residue adds 2mol/L hydrochloric acid 30ml, and reflux 1 hour is filtered, and filtrate adds the jolting of 30ml ether extracts, water bath method ether, then make to dissolve with chloroform 1ml, as need testing solution.Separately get diosgenin reference substance, make every 1ml containing the solution of 2mg, product solution in contrast with chloroform.Test according to thin layer chromatography (annex VI B of Chinese Pharmacopoeia), draw the each 10 μ l of above-mentioned two kinds of solution, put respectively on same silica gel g thin-layer plate, taking chloroform-methanol (volume ratio is as 95:5) as developing solvent, launch, take out, dry, with 5% phosphomolybdic acid ethanol solution colour developing, dry approximately 10 minutes at 105 DEG C, in test sample chromatograph, with the corresponding position of reference substance chromatograph on, the speckle of aobvious same color.
(2) get the lower sample liquid of discriminating (1) item and make need testing solution.Separately get emodin, chrysophanol reference substance chloroform and make every 1ml respectively containing the solution of 1mg, product solution in contrast.Test according to thin layer chromatography (annex VI B of Chinese Pharmacopoeia), draw respectively the each 10 μ l of above-mentioned two kinds of solution, put respectively on same silica gel g thin-layer plate, taking the upper solution of petroleum ether-ethyl acetate-formic acid (volume ratio is as 15:5:1) as developing solvent, launch, take out, dry, put under uviol lamp and inspect, in test sample chromatograph, with contrast on the corresponding position of chromatograph, the speckle of aobvious same color.
In this product chromatograph, with corresponding reference substance chromatograph relevant position on, the speckle of aobvious same color.
compared with prior art, its beneficial effect is in the present invention:(1) the present invention goes the preparation method of scorching tincture simple, and the scorching tincture that goes making has good removing damp-heat, eliminating fire and detoxication, blood circulation promoting and blood stasis dispelling, the effect of reducing swelling and alleviating pain and antiinflammatory evacuation of pus; (2) product of the present invention cures mainly traumatic injury, trauma infection contamination, carbuncle, furuncle, mosquito bite, itchy skin eruption; (3) compared with prior art, removing scorching tincture is pure Chinese medicinal preparation, and side effect is little, and production technology is easy, cheap.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is described in further detail.
Embodiment 1
Remove scorching tincture, comprise the following component according to parts by weight meter: 22 parts of Rhizoma Paridis, 32 parts of Radix Et Rhizoma Rhei, 4 parts, Flos Carthami, 7 parts of the Radixs Angelicae Dahuricae, 15 parts of Rhizoma Polygoni Cuspidati, 7 parts of Radix Arnebiae (Radix Lithospermi)s, 7 parts of Radix Aconiti Kusnezoffii, 11 parts of RADIX PSAMMOSILENEs, 2 parts of Semen Strychni, 16 parts of Rhizoma Arisaematis, 16 parts of Radix Sophorae Flavescentiss, 15 parts of Radix Salviae Miltiorrhizaes, 4 parts of Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani)s.
The present embodiment goes the preparation method of scorching tincture, comprises the steps:
Step (1) is ground into coarse powder by Rhizoma Paridis, Radix Et Rhizoma Rhei, Flos Carthami, the Radix Angelicae Dahuricae, Rhizoma Polygoni Cuspidati, Radix Arnebiae (Radix Lithospermi), Radix Aconiti Kusnezoffii, RADIX PSAMMOSILENE, Semen Strychni, Rhizoma Arisaematis, Radix Sophorae Flavescentis, Radix Salviae Miltiorrhizae together with Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani);
Step (2), makes solvent with 68% ethanol, and the coarse powder dipping that step (1) is obtained spends the night, and is then added in percolator, then adds 62% ethanol to liquid level to exceed medical material surface, places 20 hours;
Step (3), after step (2) is placed, carries out percolation extraction using 63% ethanol as leaching solvent, and regulating extracting solution is 55% containing alcohol amount, leaves standstill 24h, to obtain final product.
Embodiment 2
Remove scorching tincture, comprise the following component according to parts by weight meter: 26 parts of Rhizoma Paridis, 34 parts of Radix Et Rhizoma Rhei, 5 parts, Flos Carthami, 10 parts of the Radixs Angelicae Dahuricae, 18 parts of Rhizoma Polygoni Cuspidati, 9 parts of Radix Arnebiae (Radix Lithospermi)s, 9 parts of Radix Aconiti Kusnezoffii, 14 parts of RADIX PSAMMOSILENEs, 3 parts of Semen Strychni, 18 parts of Rhizoma Arisaematis, 18 parts of Radix Sophorae Flavescentiss, 18 parts of Radix Salviae Miltiorrhizaes, 7 parts of Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani)s.
The present embodiment goes the preparation method of scorching tincture, comprises the steps:
Step (1) is ground into coarse powder by Rhizoma Paridis, Radix Et Rhizoma Rhei, Flos Carthami, the Radix Angelicae Dahuricae, Rhizoma Polygoni Cuspidati, Radix Arnebiae (Radix Lithospermi), Radix Aconiti Kusnezoffii, RADIX PSAMMOSILENE, Semen Strychni, Rhizoma Arisaematis, Radix Sophorae Flavescentis, Radix Salviae Miltiorrhizae together with Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani);
Step (2), makes solvent with 62% ethanol, and the coarse powder dipping that step (1) is obtained spends the night, and is then added in percolator, then adds 68% ethanol to liquid level to exceed medical material surface, places 26 hours;
Step (3), after step (2) is placed, carries out percolation extraction using 63% ethanol as leaching solvent, and regulating extracting solution is 65% containing alcohol amount, leaves standstill 12h, to obtain final product.
Embodiment 3
Remove scorching tincture, comprise the following component according to parts by weight meter: 25 parts of Rhizoma Paridis, 33.3 parts of Radix Et Rhizoma Rhei, 4.2 parts, Flos Carthami, 8.4 parts of the Radixs Angelicae Dahuricae, 16.7 parts of Rhizoma Polygoni Cuspidati, 8.4 parts of Radix Arnebiae (Radix Lithospermi)s, 8.4 parts of Radix Aconiti Kusnezoffii, 12.5 parts of RADIX PSAMMOSILENEs, 2.5 parts of Semen Strychni, 16.7 parts of Rhizoma Arisaematis, 16.7 parts of Radix Sophorae Flavescentiss, 16.7 parts of Radix Salviae Miltiorrhizaes, 5.8 parts of Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani)s.
The present embodiment goes the preparation method of scorching tincture, comprises the steps:
Step (1) is ground into coarse powder by Rhizoma Paridis, Radix Et Rhizoma Rhei, Flos Carthami, the Radix Angelicae Dahuricae, Rhizoma Polygoni Cuspidati, Radix Arnebiae (Radix Lithospermi), Radix Aconiti Kusnezoffii, RADIX PSAMMOSILENE, Semen Strychni, Rhizoma Arisaematis, Radix Sophorae Flavescentis, Radix Salviae Miltiorrhizae together with Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani);
Step (2), makes solvent with 65% ethanol, and the coarse powder dipping that step (1) is obtained spends the night, and is then added in percolator, then adds 65% ethanol to liquid level to exceed medical material surface, places 24 hours;
Step (3), after step (2) is placed, carries out percolation extraction using 63% ethanol as leaching solvent, and regulating extracting solution is 60% containing alcohol amount, leaves standstill 18h, to obtain final product.
Product of the present invention is the supernatant liquid of yellowish-brown, after testing, and amount of alcohol: 55%～65%; Total solid: leave over residue and should be not less than 2.0%; Other: should meet every regulation relevant under tincture item (annex I N of Chinese Pharmacopoeia version in 2010).
Product usage of the present invention is external, and for several times, spray or put affected part on the skin every day.Sealing, puts the storage of shady and cool place.Effect duration is 12 months.Pregnant and lactant women forbidding.
To the itchy skin eruption patient of different symptoms, use product of the present invention to spray treatment, concrete as table 1.
Table 1
Adopt product of the present invention to hinder infected patient to 100 exceptions simultaneously and spray treatment, concrete as table 2.
Claims (6)
1. remove scorching tincture, it is characterized in that comprising the following component according to parts by weight meter: Rhizoma Paridis 22-26 part, Radix Et Rhizoma Rhei 32-34 part, Flos Carthami 4-5 part, Radix Angelicae Dahuricae 7-10 part, Rhizoma Polygoni Cuspidati 15-18 part, Radix Arnebiae (Radix Lithospermi) 7-9 part, Radix Aconiti Kusnezoffii 7-9 part, RADIX PSAMMOSILENE 11-14 part, Semen Strychni 2-3 part, Rhizoma Arisaematis 16-18 part, Radix Sophorae Flavescentis 16-18 part, Radix Salviae Miltiorrhizae 15-18 part, Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) 4-7 part.
2. according to claim 1ly remove scorching tincture, it is characterized in that comprising the following component according to parts by weight meter: 25 parts of Rhizoma Paridis, 33.3 parts of Radix Et Rhizoma Rhei, 4.2 parts, Flos Carthami, 8.4 parts of the Radixs Angelicae Dahuricae, 16.7 parts of Rhizoma Polygoni Cuspidati, 8.4 parts of Radix Arnebiae (Radix Lithospermi)s, 8.4 parts of Radix Aconiti Kusnezoffii, 12.5 parts of RADIX PSAMMOSILENEs, 2.5 parts of Semen Strychni, 16.7 parts of Rhizoma Arisaematis, 16.7 parts of Radix Sophorae Flavescentiss, 16.7 parts of Radix Salviae Miltiorrhizaes, 5.8 parts of Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani)s.
3. preparation method of removing scorching tincture claimed in claim 1, is characterized in that comprising the steps:
Step (1) is ground into coarse powder by Rhizoma Paridis, Radix Et Rhizoma Rhei, Flos Carthami, the Radix Angelicae Dahuricae, Rhizoma Polygoni Cuspidati, Radix Arnebiae (Radix Lithospermi), Radix Aconiti Kusnezoffii, RADIX PSAMMOSILENE, Semen Strychni, Rhizoma Arisaematis, Radix Sophorae Flavescentis, Radix Salviae Miltiorrhizae together with Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani);
Step (2), makes solvent with 62-68% ethanol, and the coarse powder dipping that step (1) is obtained spends the night, and is then added in percolator, then adds 62-68% ethanol to liquid level to exceed medical material surface, places 20-26 hour;
Step (3), after step (2) is placed, carries out percolation extraction using ethanol as leaching solvent, and regulating extracting solution is 55-65% containing alcohol amount, leaves standstill, and to obtain final product.
4. preparation method of removing scorching tincture according to claim 3, its feature in described step (3) using 63% ethanol as leach solvent.
5. preparation method of removing scorching tincture according to claim 3, its feature time of repose in described step (3) is 12-24h.
6. preparation method of removing scorching tincture according to claim 3, is characterized in that comprising the steps:
Step (1) is ground into coarse powder by Rhizoma Paridis, Radix Et Rhizoma Rhei, Flos Carthami, the Radix Angelicae Dahuricae, Rhizoma Polygoni Cuspidati, Radix Arnebiae (Radix Lithospermi), Radix Aconiti Kusnezoffii, RADIX PSAMMOSILENE, Semen Strychni, Rhizoma Arisaematis, Radix Sophorae Flavescentis, Radix Salviae Miltiorrhizae together with Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani);
Step (2), makes solvent with 65% ethanol, and the coarse powder dipping that step (1) is obtained spends the night, and is then added in percolator, then adds 65% ethanol to liquid level to exceed medical material surface, places 24 hours;
Step (3), after step (2) is placed, carries out percolation extraction using ethanol as leaching solvent, and regulating extracting solution is 55-65% containing alcohol amount, leaves standstill, and to obtain final product.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410463501.3A CN104189397B (en) | 2014-09-12 | 2014-09-12 | Remove scorching tincture and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410463501.3A CN104189397B (en) | 2014-09-12 | 2014-09-12 | Remove scorching tincture and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN104189397A true CN104189397A (en) | 2014-12-10 |
| CN104189397B CN104189397B (en) | 2017-09-29 |
Family
ID=52074869
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410463501.3A Active CN104189397B (en) | 2014-09-12 | 2014-09-12 | Remove scorching tincture and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104189397B (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106420973A (en) * | 2016-08-30 | 2017-02-22 | 中南民族大学 | Medicine composition for treating bee, scorpion and mosquito bites, and preparation and application thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2441440A1 (en) * | 2010-10-18 | 2012-04-18 | Luigina Straccia | Natural pharmacological aid for prevention of periodontal inflammatory disease |
| CN102861217A (en) * | 2012-09-25 | 2013-01-09 | 黄盛焕 | External emplastrum for treating malignant boil, sores and carbuncles |
-
2014
- 2014-09-12 CN CN201410463501.3A patent/CN104189397B/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2441440A1 (en) * | 2010-10-18 | 2012-04-18 | Luigina Straccia | Natural pharmacological aid for prevention of periodontal inflammatory disease |
| CN102861217A (en) * | 2012-09-25 | 2013-01-09 | 黄盛焕 | External emplastrum for treating malignant boil, sores and carbuncles |
Non-Patent Citations (2)
| Title |
|---|
| 张兆旺: "《中药药剂学》", 31 January 2003 * |
| 王吉侯: "去炎酊治疗痈疽疗疖的临床观察", 《新中医》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106420973A (en) * | 2016-08-30 | 2017-02-22 | 中南民族大学 | Medicine composition for treating bee, scorpion and mosquito bites, and preparation and application thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN104189397B (en) | 2017-09-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103040924B (en) | Radix millettiae speciosae extract and application thereof in preparing drugs for treating osteoporosis | |
| CN101953980B (en) | Allium macrostemon and pepperweed seed mixture for treating chronic obstructive pulmonary disease (COPD) by adopting phlegm removing and turbidity resolving method | |
| CN104189397A (en) | Anti-inflammatory tincture and preparing method thereof | |
| CN103006782B (en) | Ficus auriculata extract and application thereof in preparation of medicine used for treating osteoporosis | |
| CN103251908B (en) | Hair-restorer and preparation method thereof | |
| CN103565909B (en) | A kind of licorice root particles and preparation method thereof | |
| CN103356915B (en) | Decoction for treatment of asthma | |
| CN103263623A (en) | Traditional Chinese medicine for treating solar dermatitis | |
| CN103239594B (en) | Topical pharmaceutical composition for preventing and treating canine acariasis disease and preparation method thereof | |
| CN101474332A (en) | Danxiang capsule and preparation method thereof | |
| CN102429973B (en) | Preparation method of traditional Chinese medicinal extract with effect of enhancing fracture healing | |
| CN102895507A (en) | Chinese medicine for treating leukoplakia vulvae and preparation method thereof | |
| CN106177075A (en) | The cold compress bag for the treatment of allergic skin and preparation method thereof | |
| CN105148075A (en) | Traditional Chinese medicine ointment promoting wound healing | |
| CN106109625B (en) | A kind of preparation method of Chinese medicine preparation for heart failure treatment | |
| CN105477362A (en) | Preparation method of traditional Chinese medicinal composition for treating gastritis and preparation prepared by adopting preparation method | |
| CN106913599A (en) | Maidenhair extractive of general flavone preparation method and applied in resistance prostatitis medicine | |
| CN103494979A (en) | Traditional Chinese medicine patch for relieving pains | |
| CN103566327A (en) | Asthma-relieving decoction and preparation method thereof | |
| CN104225168A (en) | Rhizoma paridis total saponin cataplasm and preparation method thereof | |
| CN104524281A (en) | External traditional Chinese medicine spray for treating allergic rhinitis and preparation method of external traditional Chinese medicine | |
| CN103623305A (en) | Chinese medicinal formula capable of inhibiting acquired immune deficiency syndrome (AIDS) | |
| CN104398783A (en) | Constipation removal Chinese herbal preparation and preparation and using method thereof | |
| CN102008529A (en) | Manchurian wildginger traditional Chinese medicine preparation for treating oral ulcers by external application on feet | |
| CN103816321A (en) | Traditional Chinese medicine liquid for treating dermatophytosis |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |