CN104173715A - Traditional Chinese veterinary drug for curing endometriosis of dairy cows after delivery and preparation method thereof - Google Patents

Abstract

The invention relates to a traditional Chinese veterinary drug for curing endometriosis of dairy cows after delivery and a preparation method thereof. The traditional Chinese veterinary drug comprises the following ingredients, by weight, 15-25 parts of motherwort, 10-20 parts of dandelion, 5-15 parts of angelica; 5-10 parts of epimedium, 5-9 parts of fried folium artemisiae argyi, 5-7 parts of fried bighead atractylodes rhizome, 4-8 parts of Codonopsis pilosula, 4-8 parts of astragalus membranaceus, 4-8 parts of hawthorn, 4-7 parts of Semen Cuscutae, 3-8 parts of folium isatidis, 3-5 parts of Radix Ophiopogonis, 2-5 parts of fructus aurantii immaturus, 2-4 parts of peach seed, 2-4 parts of Mangnolia officinalis, 2-3 parts of safflower, 1-3 parts of lonicera japonica and 1-2 parts of liquorice. One or more components selected from pericarpium citri reticulatae, Pinellia tuber, trogopterus dung, radix rehmanniae preparata, forsythia and rhizoma zingiberis can be added. The traditional Chinese veterinary drug for curing endometriosis of dairy cows after delivery belongs to a natural pure traditional Chinese medicinal preparation. The method for curing endometriosis of dairy cows after delivery by the use of the traditional Chinese veterinary drug is simple and easy to operate, has remarkable effects and has no side effect. By the use of the traditional Chinese veterinary drug, there is no drug residue in milk, and cows can absorb the drug well if the drug is taken orally. The technology is simple and suitable for industrial production. The drug is simple, convenient and fast to use, and is more suitable for curing endometriosis of dairy cows after delivery on a large-scale farm than other dosage forms.

Description

A kind of milch cow endometriotic herbal medicine in puerperal and preparation method thereof for the treatment of

Technical field

The invention belongs to field of medicine preparing technology, especially a kind of milch cow endometriotic herbal medicine in puerperal and preparation method thereof for the treatment of.

Background technology

Fast development along with China's economy, improving constantly of living standards of the people, people are also constantly soaring to the demand of milk, yet along with the increase of milch cow quantity, milch cow endometriosis has just become a very common disease, dairy farmer has many knotty problems when treatment, but the residue problem of medicine, in milch cow 12h in puerperal, afterbirth is not discharged or still for all discharging, is called endometriosis (RFM), and milch cow endometriosis claims again retained afterbirth or Placenta Hominis to stagnate.Be milch cow a kind of common disease in puerperal, sickness rate is 30%-50%.Milch cow endometriosis, very easily excites the generation of puerperal disease, causes many high yield cows to be eliminated in advance.Even jeopardize the life of milch cow, have a strong impact on the development of cattle-raising, brought huge economic loss to cowboying family.Pathogenic factor milch cow endometriosis in puerperal has and complicated pathogenic factor, and inertia of uterus is the most direct modal reason of endometriosis, and one feedstuff is simple, hypotrophy, vitamin A, vitamin E and calcium, the shortage of selenium and other trace elements; Its two with the hypomotility in pregnancy period, the obesity of milch cow, fetus is excessive, fetus, amniotic fluid is too much, miscarriage, difficult labour, the nursing of vulneratio uteri and pregnancy duration is improper; Its three incorrect artificial practise midwifery and exopathogen are invaded people, as Brucella, Listeria monocytogenes, mycete, virus, trichomonacide infection etc. can cause endometriosis.Clinical symptoms and diagnose clinically primary disease (RFM) can be divided into two kinds of whole endometriosis and parton endometriosis.All endometriosis is that milch cow afterbirth in puerperal is all stagnated outside intrauterine or vaginal orifice, is band shape and hangs down, and the initial stage is soil Red, along with the corruption one-tenth of afterbirth is light grey.1-2 days afterbirths start corrupt longlyer while decomposing winter during the broiling summer, from intravaginal, flow out dirty red stench liquid, and afterbirth fragment and pus, flow out a lot during sleeping ground of cattle.Milch cow starts to occur General Symptoms thereupon, loss of appetite, and lassitude, usually hogback is exerted duty, squeezes urine.Fervescence, pulse, accelerated breathing.Although endometriosis is the commonly encountered diseases in cow disease, the consequence causing is very serious, the sickness rate such as endometriotic cattle its metabolic disease, mastitis, metritis occurs also correspondingly only high than normal cattle.

According to the endometriotic pathogeny analysis of milch cow, the measure of its common prevention mainly contains and guarantees dairy cow nutrition balance, active treatment endometritis before breeding, antenatal postpartum care.Conventional antibiotic and the hormone medicines such as chlortetracycline, oxytetracycline, pituitrin, ergometrine of adopting while taking Drug therapy, even adopts operation stripping clothing.Operation stripping clothing is cumbersome and easily infect, and uses antibiotic and hormone medicine to have medicine residual and easily produce drug resistance, unfavorable to milch cow and milk.

Chinese veterinarian thinks that milch cow endometriosis consumes the result that impairment of QI blood, Qi and blood deficiency, QI-blood circulation are smooth, uterine motility weakens while being production, and its treatment be take invigorating qi and benefiting blood as main, and assistant is with the stagnant blood stasis dispelling of row, inducing diuresis to remove edema.The present invention utilizes domestic a large amount of Chinese herbal medicine resource, according to Chinese medical theory, rationally utilize Chinese herbal medicine function to cure mainly reasonable compatibility and use a kind of endometriotic herbal medicine of milch cow and preparation method thereof for the treatment of of developing, this product is pure Chinese medicinal preparation, and safe green no drug residue, have no side effect.Have dosage accurately, steady quality, transportation, store, carry, apply all more convenient; Mechanization production, output is large, and cost is low, and sanitary standard also easily reaches.

Summary of the invention

The object of the invention is to overcome the deficiency of existing preparation and technology, propose a kind of safe, green, no drug residue, compatibility rationally, convenient drug administration, technique be simple, reliable for effect, is easy to a kind of endometriotic herbal medicine of milch cow and preparation method thereof for the treatment of of promoting.

The technical scheme that the present invention realizes object is:

Treat the endometriotic herbal medicine of milch cow, form component and mass fraction thereof and be respectively:

Herba Leonuri 15-25 part; Herba Taraxaci 10-20 part; Radix Angelicae Sinensis 5-15 part; Herba Epimedii 5-10 part; Folium Artemisiae Argyi (parched) 5-9 part; Rhizoma Atractylodis Macrocephalae (parched) 5-7 part; Radix Codonopsis 4-8 part; Radix Astragali 4-8 part; Fructus Crataegi 4-8 part; Semen Cuscutae 4-7 part; Folium Isatidis 3-8 part; Radix Ophiopogonis 3-5 part; Fructus Aurantii Immaturus 2-5 part; Semen Persicae 2-4 part; Cortex Magnoliae Officinalis 2-4 part; Flos Carthami 2-3 part; Flos Lonicerae 1-3 part; Radix Glycyrrhizae 1-2 part.

Can add one or more in Pericarpium Citri Reticulatae, the Rhizoma Pinelliae, Oletum Trogopterori, Radix Rehmanniae Preparata, Fructus Forsythiae, Rhizoma Zingiberis.

A kind of endometriotic herbal medicine of milch cow and preparation method thereof for the treatment of, step is:

(1) by prescription, take Herba Leonuri, Herba Epimedii, Semen Cuscutae, Radix Angelicae Sinensis, Herba Taraxaci, Flos Carthami and Semen Persicae and adopt Chinese medicine grinder co-grinding, cross respectively 80 mesh standard sieves, obtain Chinese crude drug fine powder;

(2) other Chinese medicines such as Flos Lonicerae are pulverized respectively, crossed 80 mesh standard sieves;

(3) by prescription, take each Chinese crude drug fine powder in (2), mix 15 minutes;

(4) (1) is dropped in (3) and mixed 20 minutes, obtain a kind of milch cow endometriotic herbal medicine in puerperal for the treatment of.

Advantage of the present invention and beneficial effect are:

1, the present invention has innovated the endometriotic Chinese herbal medicine compatibility agent for the treatment of milch cow, fully demonstrated the advantage in the Chinese herbal medicine application of Chinese medicine big country, the important breakthrough of the new application technology of domestic herbal prescription, for Chinese medicine novel composing prescription has been opened up in the endometriotic treatment of domestic milch cow.

2, the present invention has invigorating qi and benefiting blood, and the effects such as the stagnant blood stasis dispelling of row, inducing diuresis to remove edema, heat-clearing and toxic substances removing, pain relieving evacuation of pus, to strengthen the anti-disease ability of milch cow immunity and body.

3, the technique the present invention relates to has that production equipment is simple, technique is simple, processing ease, advantage easy to use, to be applicable to industrialization, made up the blank of milch cow endometriosis treatment aspect, domestic veterinary drug market, innovated the Chinese prescription of reasonable compatibility, can realize rapidly industrialization, promote the development of aquaculture.

The specific embodiment

Below by specific embodiment, the invention will be further described, and following examples are descriptive, is not determinate, can not limit protection scope of the present invention with this.

Herba Leonuri 15-25 part; Herba Taraxaci 10-20 part; Radix Angelicae Sinensis 5-15 part; Herba Epimedii 5-10 part; Folium Artemisiae Argyi (parched) 5-9 part; Rhizoma Atractylodis Macrocephalae (parched) 5-7 part; Radix Codonopsis 4-8 part; Radix Astragali 4-8 part; Fructus Crataegi 4-8 part; Semen Cuscutae 4-7 part; Folium Isatidis 3-8 part; Radix Ophiopogonis 3-5 part; Fructus Aurantii Immaturus 2-5 part; Semen Persicae 2-4 part; Cortex Magnoliae Officinalis 2-4 part; Flos Carthami 2-3 part; Flos Lonicerae 1-3 part; Radix Glycyrrhizae 1-2 part.

Can add one or more in Pericarpium Citri Reticulatae, the Rhizoma Pinelliae, Oletum Trogopterori, Radix Rehmanniae Preparata, Fructus Forsythiae, Rhizoma Zingiberis.

Embodiment 1:

Treat the endometriotic herbal medicine of milch cow, it forms component and parts by weight are respectively (by every bag of 1000g supplementary material proportioning, following examples are same):

15 parts of Herba Leonuris; 10 parts of Herba Taraxacis; 5 parts of Radix Angelicae Sinensis; 5 parts of Herba Epimedii; 5 parts of Folium Artemisiae Argyi (parched); 5 parts of Rhizoma Atractylodis Macrocephalae (parched)s; 4 parts of Radix Codonopsis; 4 parts of the Radixs Astragali; 4 parts of Fructus Crataegis; 4 parts of Semen Cuscutae; 3 parts of Folium Isatidiss; 3 parts of Radix Ophiopogonis; 2 parts of Fructus Aurantii Immaturuss; 2 parts, Semen Persicae; 2 parts of Cortex Magnoliae Officinalis; 2 parts, Flos Carthami; 1 part of Flos Lonicerae; 1 part, Radix Glycyrrhizae.

A kind of endometriotic herbal medicine of milch cow and preparation method thereof for the treatment of, comprises the steps:

(1) by prescription, take Herba Leonuri, Herba Epimedii, Semen Cuscutae, Radix Angelicae Sinensis, Herba Taraxaci, Flos Carthami and Semen Persicae and adopt Chinese medicine grinder co-grinding, cross respectively 80 mesh standard sieves, obtain Chinese crude drug fine powder;

(2) other Chinese medicines such as Flos Lonicerae are pulverized respectively, crossed 80 mesh standard sieves;

(3) by prescription, take each Chinese crude drug fine powder in (2), mix 15 minutes;

(4) (1) is dropped in (3) and mixed 20 minutes, obtain a kind of milch cow endometriotic herbal medicine in puerperal for the treatment of.

Embodiment 2:

Treat the endometriotic herbal medicine of milch cow, it forms component and parts by weight are respectively:

20 parts of Herba Leonuris; 15 parts of Herba Taraxacis; 10 parts of Radix Angelicae Sinensis; 8 parts of Herba Epimedii; 7 parts of Folium Artemisiae Argyi (parched); 6 parts of Rhizoma Atractylodis Macrocephalae (parched)s; 5 parts of Radix Codonopsis; 5 parts of the Radixs Astragali; Fructus Crataegi 54-8 part; 5 parts of Semen Cuscutae; 6 parts of Folium Isatidiss; 4 parts of Radix Ophiopogonis; 3 parts of Fructus Aurantii Immaturuss; 3 parts, Semen Persicae; 3 parts of Cortex Magnoliae Officinalis; 2.5 parts, Flos Carthami; 2 parts of Flos Loniceraes; 1.5 parts, Radix Glycyrrhizae.

The step of the present embodiment preparation method is same as embodiment 1.

Embodiment 3:

Treat the endometriotic herbal medicine of milch cow, it forms component and parts by weight are respectively:

25 parts of Herba Leonuris; 20 parts of Herba Taraxacis; 15 parts of Radix Angelicae Sinensis; 10 parts of Herba Epimedii; 5 parts of Folium Artemisiae Argyi (parched); 7 parts of Rhizoma Atractylodis Macrocephalae (parched)s; 8 parts of Radix Codonopsis; 8 parts of the Radixs Astragali; 8 parts of Fructus Crataegis; 7 parts of Semen Cuscutae; 8 parts of Folium Isatidiss; 5 parts of Radix Ophiopogonis; 5 parts of Fructus Aurantii Immaturuss; 4 parts, Semen Persicae; 4 parts of Cortex Magnoliae Officinalis; 3 parts, Flos Carthami; 3 parts of Flos Loniceraes; 2 parts, Radix Glycyrrhizae.

The step of the preparation method of the present embodiment is same as embodiment 1.

Detect data: it is 99.8% that this invention is used for the treatment of milch cow endometriosis in puerperal effective percentage, and cure rate is 98.7%.

Claims (3)

1. treat milch cow endometriotic herbal medicine in puerperal and preparation method thereof for one kind, it is characterized in that: form component and mass fraction thereof and be respectively:

Herba Leonuri 15-25 part; Herba Taraxaci 10-20 part; Radix Angelicae Sinensis 5-15 part; Herba Epimedii 5-10 part; Folium Artemisiae Argyi (parched) 5-9 part; Rhizoma Atractylodis Macrocephalae (parched) 5-7 part; Radix Codonopsis 4-8 part; Radix Astragali 4-8 part; Fructus Crataegi 4-8 part; Semen Cuscutae 4-7 part; Folium Isatidis 3-8 part; Radix Ophiopogonis 3-5 part; Fructus Aurantii Immaturus 2-5 part; Semen Persicae 2-4 part; Cortex Magnoliae Officinalis 2-4 part; Flos Carthami 2-3 part; Flos Lonicerae 1-3 part; Radix Glycyrrhizae 1-2 part.

2. a kind of milch cow endometriotic herbal medicine in puerperal and preparation method thereof for the treatment of according to claim 1, is characterized in that: describedly add one or more in Pericarpium Citri Reticulatae, the Rhizoma Pinelliae, Oletum Trogopterori, Radix Rehmanniae Preparata, Fructus Forsythiae, Rhizoma Zingiberis

3. treat milch cow endometriotic herbal medicine in puerperal and preparation method thereof for one kind, it is characterized in that: the step of preparation is:

(1) by prescription, take Herba Leonuri, Herba Epimedii, Semen Cuscutae, Radix Angelicae Sinensis, Herba Taraxaci, Flos Carthami and Semen Persicae and adopt Chinese medicine grinder co-grinding, cross respectively 80 mesh standard sieves, obtain Chinese crude drug fine powder;

(2) other Chinese medicines such as Flos Lonicerae are pulverized respectively, crossed 80 mesh standard sieves;

(3) by prescription, take each Chinese crude drug fine powder in (2), mix 15 minutes;

(4) (1) is dropped in (3) and mixed 20 minutes, obtain a kind of milch cow endometriotic herbal medicine in puerperal for the treatment of.