CN104134214B - A kind of storage of digital slices image and display methods based on image pyramid layering - Google Patents

A kind of storage of digital slices image and display methods based on image pyramid layering Download PDF

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CN104134214B
CN104134214B CN201410364308.4A CN201410364308A CN104134214B CN 104134214 B CN104134214 B CN 104134214B CN 201410364308 A CN201410364308 A CN 201410364308A CN 104134214 B CN104134214 B CN 104134214B
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image
digital slices
data
pyramid
pictorial element
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CN104134214A (en
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叶志前
姜磊
汤纬民
王鑫鑫
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HANGZHOU ZHUOTENG INFORMATION TECHNOLOGY Co Ltd
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HANGZHOU ZHUOTENG INFORMATION TECHNOLOGY Co Ltd
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Abstract

The present invention relates to digital information processing, more particularly to a kind of the storage of digital slices image and display methods, storage method based on image pyramid layering include:Step is 1.:The pictorial element of slice is obtained, is labeled as the 0th layer, and the tomographic image data are divided into 256 × 256 dimension data blocks, and record respective coordinates position (X, Y);Step is 2.:Using the pictorial element center of preceding layer as basic point, row, column size is reduced according to set proportion, then sampled and mark the number of plies;Step is 3.:It repeats 2. total amount of data that step is obtained to sampling and has reached the set number of plies;Step is 4.:By the obtained pictorial element of sampling by the sequential build digital slices pyramid of label.The present invention can quickly show the close progressive of image, and the method for displaying image of the present invention alleviates the demand to browsing terminal equipment performance significantly under limited network bandwidth conditions, ensure that digital slices browsing reaches clinical diagnosis requirement with display efficiency.

Description

A kind of storage of digital slices image and display methods based on image pyramid layering
Technical field
The present invention relates to digital slices image processing techniques, more particularly to a kind of number based on image pyramid layering is cut Picture stores and display methods.
Background technology
Country's basic hospital pathologist shortage, pathological diagnosis level are limited at present, and high-quality pathological diagnosis resource mainly collects In in big city large hospital, base patient wants to obtain accurate pathological diagnosis often by patient or kith and kin by pathological section It is sent to the consultation of doctors of higher level's hospital pathology department in person, this had both allowed patient to take considerable time waiting diagnostic result, and also to have allowed patient to pay More expenses.Digital pathology can realize that base's pathologist and patient are stayed indoor enough, you can accurate pathological diagnosis opinion is obtained, It realizes really " one-stop Pathology Consultation service ", alleviates the present situation of China's pathology uneven geographical distribution of resources.
Pathology slide passes through the seamless spliced digital slices for generating the full visual field of digital pathological section scanner.Digital slices figure As being different from regular medication check image, belong to large capacity image data.Under normal circumstances, 1.5cm × 1.5cm pathology slides The data volume that the scanning of sample 40x multiplying powers generates about in 5G or so, how efficient storage digital slices image and in common office Realize that digital slices fast browsing and display are that digital pathology promotes the pass that must be solved with application under the conditions of domain or wide area network One of key problem.
Invention content
The object of the present invention is to provide a kind of efficiently quickly digital slices image storages based on image pyramid layering And display methods.
The object of the present invention is achieved like this:
A kind of digital slices image storage method based on image pyramid layering, including:
Step is 1.:The pictorial element of slice is obtained, is labeled as the 0th layer, and the tomographic image data are divided into 256 × 256 Dimension data block, and record the tomographic image center respective coordinates position (X, Y);
Step is 2.:The pictorial element of preceding layer is sampled:Using the pictorial element center of preceding layer as basic point, according to setting Fixed scale smaller row, column size, then the number of plies is sampled and is marked, while the tomographic image data are divided into 256 × 256 rulers Very little data block, and records center position respective coordinates position (X ', Y ');
Step is 3.:It repeats 2. total amount of data that step is obtained to sampling and has reached the set number of plies;
Step is 4.:The pictorial element that sampling is obtained is obtained by the sequential build digital slices pyramid of label, first sampling Pictorial element be located at below the pictorial element that post-sampling obtains.
Preferably, the step 2. in, the serial number of label by natural number sequentially.
Preferably, the ratio is 0.5.
Preferably, digital slices pyramid data stores 7 layers.
Preferably, data sampling method is realized using improved Wavelet Transformation Algorithm:
Enable f (x, y) ∈ L2Indicate a 2D signal, x, y indicate its abscissa and ordinate respectively.Φ (x, y) is indicated Two-dimentional wavelet, then the continuous wavelet transform of f (x, y) be:
Wherein, b1, b2It is the shift factor along image abscissa and ordinate direction, a is scale factor, WT (a;b1, b2) To pass through obtained wavelet coefficient after transformation.
When 2-d wavelet meets admissibility condition:
Then there is corresponding wavelet inverse transformation, i.e.,:
In practical applications, common wavelet function is the binary function of variable separable:
Φ (x, y)=Φ1(x)Φ2(y),
Two-dimentional multiscale analysis is exported by one-dimensional multiscale analysis, and then exports 2-d wavelet space and wavelet function. The following breakdowns of f (x, y) are expressed:
Wherein:
First item is Continuous Approximations of the f (x, y) at scale j in formula (4), j=0, when 1,2,3.... different value, is obtained Approaching under different scale.Formula (5) is known as discrete details of the f (x, y) under scale, that is, the data after sampling.
A kind of digital slices method for displaying image based on image pyramid layering, including
Step is 1.:The request service of user end to server system transmission data, the data request service have parameter number The number of plies, current data block X-coordinate value, current data block Y-coordinate value where word is sliced identification id, current data block;
Step is 2.:Server system responds received data request service, opens the digital slices of affiliated ID, sends number Word slice pyramid pictorial element corresponds in the number of plies the corresponding video data block of (X, Y) coordinate value;
Step is 3.:Acquired video data block is shown according to specific dimensions in the image display area of client.
Preferably, the image of the client is shown as the data block of 256 × 256 pixels.
Preferably, the client is provided with caching mechanism comprising does not browse information preload mechanisms and has browsed letter Memory mechanism is ceased, when the new image data of client request, first detects whether client buffer area loads required data;If It is no, 2. 3. it thens follow the steps 1., if having loaded, image data is transferred from buffering area.
The present invention is prominent and beneficial compared with prior art to be had the technical effect that:
Digital slices image is presented by the way of structure image pyramid layering in the present invention, can be in limited Netowrk tape Under the conditions of width, the close progressive of image can be quickly showed, and the method for displaying image of the present invention utilizes and do not browse information pre-add Carrier aircraft system alleviates the demand to browsing terminal equipment performance significantly so that the present invention ensures that number is cut in actual application Piece is browsed reaches clinical diagnosis requirement with display efficiency.
Description of the drawings
Fig. 1 is the digital slices image schematic diagram for the image pyramid layering that the present invention is built.
Fig. 2 is the caching mechanism schematic diagram of the present invention.
Specific implementation mode
With specific embodiment, the invention will be further described below in conjunction with the accompanying drawings:
A kind of digital slices image storage method based on image pyramid layering, including:
Step is 1.:The pictorial element of slice is obtained, is labeled as the 0th layer, and the tomographic image data are divided into 256 × 256 Dimension data block, and record the tomographic image center respective coordinates position (X, Y);
Step is 2.:The pictorial element of preceding layer is sampled:Using the pictorial element center of preceding layer as basic point, according to setting Fixed scale smaller row, column size, then the number of plies is sampled and is marked, while the tomographic image data are divided into 256 × 256 rulers Very little data block, and record respective coordinates position (X ', Y ');
Step is 3.:It repeats 2. total amount of data that step is obtained to sampling and has reached the set number of plies or set sampling Row, column size;
Step is 4.:The pictorial element that sampling is obtained is obtained by the sequential build digital slices pyramid of label, first sampling Pictorial element be located at below the pictorial element that post-sampling obtains (the 0th layer of storage initial data of the invention, in the 0th layer of base I-th (i=1,2 ...) layer pyramid data is generated on plinth, the data volume in last layer pyramid is the 1/4 of next layer data, with This analogizes, until data save as the 7th layer).
Preferably, the step 2. in, the serial number of label by natural number sequentially.
Preferably, the ratio is 0.5, that is, the row, column size of last layer pictorial element is next tomographic image element The half of row, column size.
Its specific building process is as follows:
(1) bottom of tower of regulation image pyramid is 0 grade, and original image is image pyramid bottom of tower, and is divided into 256 × 256 Pixel Dimensions size data blocks;
(2) since bottom of tower, whenever the number of plies plus 1, previous tomographic image is subjected to resampling according to position correspondence, is obtained The calculation formula of i-th tomographic image, the i-th tomographic image size is as follows:
R (i)=| r (0)/2i|
C (i)=| c (0)/2i|
In formula:R (0) and c (0) indicates the row, column size of bottom of tower raw video, the i.e. height and width of raw video, r (i) and c (i) --- the row, column size of i-stage image in tower.
As shown in Figure 1, (a) is the 0th grade of image in figure, (b) is the 1st grade of image in figure, and (c) is 3rd level image in figure.
(3) sampling of specific data is realized using improved wavelet algorithm:
Enable f (x, y) ∈ L2Indicate a 2D signal, x, y indicate its abscissa and ordinate respectively.Φ (x, y) is indicated Two-dimentional wavelet, then the continuous wavelet transform of f (x, y) be:
Wherein, b1, b2It is the shift factor along image abscissa and ordinate direction, a is scale factor, WT (a;b1, b2) To pass through obtained wavelet coefficient after transformation.
When 2-d wavelet meets admissibility condition:
Then there is corresponding wavelet inverse transformation, i.e.,:
In practical applications, common wavelet function is the binary function of variable separable:
Φ (x, y)=Φ1(x)Φ2(y),
Two-dimentional multiscale analysis is exported by one-dimensional multiscale analysis, and then exports 2-d wavelet space and wavelet function. The following breakdowns of f (x, y) are expressed:
Wherein:
First item is Continuous Approximations of the f (x, y) at scale j in formula (4), j=0, when 1,2,3.... different value, is obtained Approaching under different scale.Formula (5) is known as discrete details of the f (x, y) under scale, that is, the data after sampling.
(4) data after sampling are in turn divided into 256 × 256 Pixel Dimensions size data blocks.
(5) and so on, until being building up to pinnacle of a pagoda, when digital slices data store 7 layers, i.e. series N=6.
On the basis of being layered based on image pyramid, digital slices carry out at piecemeal digital slice of data during showing Reason.When carrying out dynamic load, the data block of the data of layering and piecemeal is combined as needed, to data request service It responds, roaming switch is carried out under different display scales and resolution ratio, realize that dynamic on-demand loads map datum, greatly carry High system real time.
A kind of digital slices method for displaying image based on image pyramid layering, including
Step is 1.:The request service of user end to server system transmission data, the data request service have parameter number The number of plies, current data block X-coordinate value, current data block Y-coordinate value where word is sliced identification id, current data block;
Step is 2.:Server system respond received data request service, open belonging to ID digital slices, send with The digital slices pyramid pictorial element of described image storage method structure corresponds in the number of plies the corresponding picture number of (X, Y) coordinate value According to block;
Step is 3.:Acquired video data block is shown in the image display area of client.
Preferably, the image of the client is shown as the data block of 256 × 256 pixels.
Preferably, the client is provided with caching mechanism comprising does not browse information preload mechanisms and has browsed letter Memory mechanism is ceased, when the new image data of client request, first detects whether client buffer area loads required data;If It is no, 2. 3. it thens follow the steps 1., if having loaded, image data is transferred from buffering area.
Currently, our digital slices image is stored using Pyramid technology, it is assumed that the image number of plies is 3 layers, every layer of dimension It is 2, entire image 2G, as shown in Figure 2:
In image loading procedure, " low frequency range of the low frequency range of low frequency range " can be loaded first to buffering area, user is initial In use, call in the part image data memory show image, while load " low frequency range of the low frequency range of low frequency range " other four / tri- high-frequency informations;When user browse more specific location information when, call show " low frequency range of the low frequency range of low frequency range " other 3/4ths high-frequency informations make it further see image detail clearly, at the same backstage loaded in parallel " low frequency range of low frequency range " other 3/4ths high-frequency informations;And so on.
In actual use, buffering area is stored in the browsed region of user, and time limit is 24 hours, buffering area Size may be configured as 5GB, before image is shown, need to detect and locally whether have space.
Above-described embodiment is only presently preferred embodiments of the present invention, is not limited the scope of the invention according to this, therefore:It is all according to The equivalence changes that structure, shape, the principle of the present invention is done, should all be covered by within protection scope of the present invention.

Claims (7)

1. a kind of digital slices image storage method based on image pyramid layering, which is characterized in that including:
Step is 1.:The pictorial element of slice is obtained, is labeled as the 0th layer, and the tomographic image data are divided into 256 × 256 sizes Data block, and record the tomographic image center respective coordinates position (X, Y);
Step is 2.:The pictorial element of preceding layer is sampled:Using the pictorial element center of preceding layer as basic point, according to setting Scale smaller row, column size, then the number of plies is sampled and is marked, while the tomographic image data are divided into 256 × 256 size numbers According to block, and records center position respective coordinates position (X ', Y ');
Step is 3.:It repeats 2. total amount of data that step is obtained to sampling and has reached the set number of plies;
Step is 4.:The pictorial element that sampling is obtained is by the sequential build digital slices pyramid of label, the figure first sampled Pixel element is located at below the pictorial element that post-sampling obtains;
Wherein, the method for sampling is realized using improved Wavelet Transformation Algorithm:
Enable f (x, y) ∈ L2Indicate that a 2D signal, x, y indicate that its abscissa and ordinate, Φ (x, y) indicate two Wikis respectively This small echo, then the continuous wavelet transform of f (x, y) be:
Wherein, b1, b2It is the shift factor along image abscissa and ordinate direction, a is scale factor, WT (a;b1, b2) it is logical Cross obtained wavelet coefficient after converting.
2. a kind of digital slices image storage method based on image pyramid layering according to claim 1, feature Be, the step 2. in, the serial number of label by natural number sequentially.
3. a kind of digital slices image storage method based on image pyramid layering according to claim 1, feature It is, the ratio is 0.5.
4. a kind of digital slices image storage method based on image pyramid layering according to claim 1, feature It is, the digital slices pyramid data stores 7 layers.
5. a kind of digital slices method for displaying image based on image pyramid layering, which is characterized in that including
Step is 1.:The request service of user end to server system transmission data, the data request service have parameters number and cut The number of plies, current data block X-coordinate value, current data block Y-coordinate value where piece identification id, current data block;
Step is 2.:Server system responds received data request service, opens the digital slices of affiliated ID, sends respective layer (X, Y) coordinate value is corresponding in number, and the digital slices pyramid diagram pixel built with claim 1 described image storage method The video data block of element;
Step is 3.:Acquired video data block is shown according to specific dimensions in the image display area of client.
6. a kind of digital slices method for displaying image based on image pyramid layering according to claim 5, feature It is, the client is provided with caching mechanism comprising information preload mechanisms are not browsed and have browsed imformation memory mechanism, When the new image data of client request, first detect whether client buffer area loads required data;If it is not, thening follow the steps 2. 1. 3., if having loaded, image data is transferred from buffering area.
7. a kind of digital slices method for displaying image based on image pyramid layering according to claim 5, feature It is, the image of the client is shown as the data block of 256 × 256 pixels.
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CN105590295B (en) * 2015-12-21 2019-05-21 玖壹叁陆零医学科技南京有限公司 Pathological section display method and device
CN105740437A (en) * 2016-01-30 2016-07-06 曲阜裕隆生物科技有限公司 3D (Three-Dimensional) image storage method and display method and 3D image file format
CN106886549A (en) * 2016-08-30 2017-06-23 阿里巴巴集团控股有限公司 A kind of loading method of network picture, device and system
CN106954068A (en) * 2017-03-09 2017-07-14 广东南方数码科技股份有限公司 A kind of image data storage, read method and system
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