CN108172277B - Method and system for storing and browsing multiple-magnification digital slice image - Google Patents
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Abstract
The invention discloses a method and a system for storing and browsing a multi-time-rate digital slice image. The invention divides the whole digital slice image into a plurality of small-sized tile images, describes the positions and the layouts of the tile images by utilizing the longitude and latitude coordinates, and converts the longitude and latitude coordinates into paths and file names for storing image files by map projection transformation, thereby realizing the organization and the storage of the multi-time-rate digital slice image. The system for storing and browsing the multi-time-rate digital slice images based on the method comprises the following steps: the system comprises a metadata read-write module, a file directory management module, a tile image read-write module, a scanning map read-write module, a label image read-write module, a preview image read-write module, a longitude and latitude coordinate and image path analysis module, a digital slice reconstruction and browsing module and a file system. The method has good universality, is convenient and quick to retrieve and position, and is suitable for large-scale concurrent access of the digital slices.
Description
Technical Field
The invention belongs to the field of digital slicing, and particularly relates to a method and a system for storing and browsing a multi-magnification digital slice image. The invention is used for carrying out standardized splitting, storage and browsing on digital slice images generated by different scanning devices.
Background
Pathological examination of disease is the gold standard for disease diagnosis. At present, the pathological diagnosis of tumors, especially malignant tumors, is more regarded as an authoritative diagnosis with an asserted nature. However, pathological diagnosis is not absolutely definitive, much less universal, and has inherent subjective and objective limitations as well as other disciplines. The accuracy of pathological diagnosis depends heavily on the business level and the working experience of a pathologist, and the diagnosis conclusion is often very subjective and unilateral. Reported data show that the rate of non-compliance of different pathologists to tumor diagnosis is 20% -40%, and some diseases are even as high as 80%. On the other hand, the medical resource distribution is seriously uneven due to the unbalanced geographical development of the economic society of China. Medical resources, especially expert resources, are intensively concentrated in extra large cities such as Beijing, Shanghai, Guangzhou and regional center cities. This leads to high misdiagnosis rate of pathological diagnosis in economically lagging areas, especially remote mountainous areas, and delay of treatment due to misdiagnosis becomes a key factor of high fatality rate of serious diseases such as malignant tumor in these areas.
The advent of digital pathology slicing technology and the development of network communication technology have provided a viable path to solve the above problems. A single digital slice consists of a large number of under-lens view images, for example, 20 times of objective lens is used for scanning, and the number of the images exceeds 2000 without an optical switching mechanism, which provides a serious test for image storage and browsing. Enterprises such as domestic MacAudi (Xiamen) medical diagnosis system, Inc., Hangzhou Zongteng information technology, Inc., Ningbo Jiangfeng biological information technology, etc. provide data storage methods or systems only suitable for digital slice scanning systems of the enterprises (patent applications: 201510939657.9, 201410364308.4, 201310050964.2). However, these methods are not universal, form mutually incompatible file formats, and require a dedicated programming interface for storage and browsing, which brings a great challenge to the establishment of a regional and open digital pathology diagnosis and treatment platform.
The invention aims at the problems, image files are split and stored by utilizing longitude and latitude in a terrestrial coordinate system, image coordinates are converted into longitude and latitude coordinates by utilizing a mature map projection formula, and the rapid browsing of the multi-magnification digital slice images is realized based on an open map browsing mode. By adopting the method provided by the invention, the image is organized into directories and files according to the latitude and longitude information, the number of folders under each directory is not more than 200, and the number of image files under each bottom directory is not more than 2000. The storage method has good universality, is convenient and quick to retrieve and locate, and is suitable for large-scale concurrent access.
Disclosure of Invention
The invention aims to provide a multi-magnification digital slice image storage and browsing method which is high in speed, strong in robustness and good in universality aiming at the application requirement of large-scale concurrent access of digital slices, and provides a digital slice image storage and browsing system which is easy to realize and deploy based on the method.
In order to achieve the purpose, the invention adopts the following technical scheme to solve the problem:
a method for storing and browsing multiple-rate digital slice images comprises the following steps:
step 1: acquiring a digital slice, and acquiring a whole preview image of the digital slice;
step 2: dividing an organized part in the overall preview image of the digital slice and generating an original magnification scanning map;
and step 3: constructing an exclusive directory of the digital slice in a file system, storing metadata contents such as patient clinical information, tissue part information, slice scanning information and the like of the digital slice, and storing a whole preview image, a label image and an original magnification scanning map of the slice;
and 4, step 4: dividing the digital slice into a plurality of tile images with the same size according to an original multiplying power scanning map, and storing the tile images according to path information generated by a map projection transformation formula;
and 5: the method comprises the steps of generating a plurality of low-magnification scanning maps according to original-magnification scanning map downsampling, downsampling a digital slice according to a newly generated low-magnification scanning map, dividing the digital slice into a plurality of tile images with the same size, and storing the tile images according to path information generated by a map projection transformation formula;
step 6: and browsing the digital slices, converting the digital slices into path information of the required tile image according to the initial longitude and latitude coordinates and the scale information, and reconstructing the digital slices according to the map coordinates.
In the method, the mode of acquiring the digital slice is one of the following modes: the digital slice scanning device creates, parses an existing digital slice file, invokes a commercial digital slice system programming interface.
The size of the original magnification scan map is determined by the following method: assuming that the width of the digital slice is W, the height of the digital slice is H, the width of the tile image is m-th power of 2, and the height of the tile image is n-th power of 2, the width W of the original magnification scanning map is W0＝ceil(W/2m) Height h of original magnification scan map0＝ceil(H/2n). m and n preferably have values of 7, 8, 9, 10,the optimal value is m-n-8.
Under different multiplying powers, the size of the scanning map is represented by multiplying power z, and the width of the z multiplying power scanning map
Height of z-magnification scan map
Under different multiplying powers, the size of the reconstructed digital slice is represented by the multiplying power z, and the width W of the reconstructed digital slicez＝wz×2mReconstructing the height H of the digital slicez＝hz×2n。
In the above, ceil is the smallest integer not less than a given value.
In the method, the map projection transformation formula adopted in the step 4 is one of the following formulas:
mercator projection, gaussian-Kruger projection, universal transverse axis Mercator (UTM) projection, and Lambert equiangular (Lambert) projection. A preferred map projection transformation formula is the Mercator projection.
In the method, a tile image path is composed of information such as an exclusive directory dir, a multiplying power z, a longitude mapping value lon, a latitude mapping value lat and the like of a digital slice.
The calculation method of the superior longitude mapping value and latitude mapping value comprises the following steps:
describing the position of the tile image in the digital slice by using the pixel position (x, y) of the scan map corresponding to the magnification z, the longitude mapping value lon corresponding to x is:
the latitude mapping value lat corresponding to y is:
wherein Lo is a longitude value corresponding to the center of the digital slice, and La is a latitude value corresponding to the center of the digital slice; w is azWidth of the scanned map, h, corresponding to magnification zzThe height of the scanned map corresponding to the multiplying power z; ceil is the minimum integer not less than the given value, round is the rounding evaluation of the given value, floor is the minimum integer not more than the given value, log is the natural logarithm of the given value, tan is the tangent value of the given value, and cos is the cosine value of the given value; n is a positive integer, and the value is larger than the maximum value of the multiplying power z. The longitude map value lon and the latitude map value lat are calculated as integers.
The preferred tile image path organization method is as follows:
and generating a corresponding magnification subdirectory according to the magnification z under the exclusive directory dir of the digital slice, generating a corresponding longitude subdirectory according to the longitude mapping value lon under the magnification subdirectory, and using the latitude mapping value lat as the file name of the tile image. For the tile image with the file suffix name of type, the corresponding path information is dir \ N-z \ lon \ lat.
A system for multiple-rate digital slice image storage and browsing, comprising:
the metadata read-write module: the method is used for writing and reading the metadata contents such as patient clinical information, tissue part information, slice scanning information and the like of the digital slice;
the file directory management module: for the creation and management of a digital slice-specific directory, a corresponding tile image storage directory;
a longitude and latitude coordinate and image path analysis module: generating longitude and latitude coordinates and a file path for the tile image;
the tile image reading and writing module: the tile image is stored and read according to the longitude and latitude coordinates and the file path generated by the image path analysis module;
a preview image reading and writing module: writing and reading of the slice whole preview image;
the map scanning read-write module: down-sampling and segmenting from a global preview image of the digital slice, scanning positions for recording and reading tile images;
a label image reading and writing module: for storage and reading of slice label images;
the digital slice reconstruction and browsing module comprises: automatically retrieving the required tile images according to the clinical information, the tissue part information, the slice scanning information and the image storage information of the patient of the digital slice, and arranging the tile images according to the longitude mapping value and the latitude mapping value in a browsing window to realize the reconstruction and the browsing of the digital slice;
a file system: a file management system for managing and storing the above metadata file, tile image, preview image, scan map, label image.
In the system, the digital slice reconstruction and browsing module is provided with a boundary consisting of longitude and latitude coordinates, the center longitude of the boundary is a longitude value Lo corresponding to the center of the digital slice, and the center latitude of the boundary is a latitude value La corresponding to the center of the digital slice. A preferred value is Lo ═ La ═ 0 °.
In the system, a browsing window of a digital slice reconstruction and browsing module comprises elements such as a reconstructed slice image, a label image, a preview navigation part, a magnification selection part, a scale part, slice copyright information and the like. The label image, the preview navigation component and the magnification selection component float above the reconstructed slice image, can be dragged and can be combined. The elements have two states of display and hiding, become a schematic button in the hidden state, and click the button to switch to the display state.
The invention has the following beneficial effects:
the invention converts the storage and browsing of the digital slice into the standard storage and display of the map data, the organization of the file system meets the requirement of large-scale concurrent access, and the rapid browsing of the multi-magnification digital slice image is realized based on an open map browsing mode.
The method has good universality, is convenient and quick to retrieve and position, and is suitable for large-scale concurrent access of the digital slices;
the invention provides a method for storing and browsing multi-magnification digital slice images, which has high speed, strong robustness and good universality and aims at the application requirement of large-scale concurrent access of digital slices.
Drawings
FIG. 1 is a flow chart of the method of the present invention;
FIG. 2 is a digital slice preview image and a scan map at multiple magnifications in accordance with embodiments of the invention;
FIG. 3 is a block diagram of the system architecture of the present invention;
FIG. 4 is a diagram illustrating the composition of elements of a digital slice view window according to an embodiment of the present invention;
fig. 5 is a schematic diagram of the operation characteristics of the elements of the digital slice view window according to the embodiment of the invention.
Detailed Description
The present invention will be described in detail with reference to the accompanying drawings and examples.
The invention belongs to the field of digital slicing, and particularly relates to a method and a system for storing and browsing a multi-magnification digital slice image. The invention is used for carrying out standardized splitting, storage and browsing on digital slice images generated by different scanning devices.
As shown in fig. 1, a method for storing and browsing multiple-rate digital slice images includes the following operations:
firstly, acquiring a digital slice (101), and acquiring a digital slice whole preview image (102);
then, an organized part is divided in the whole preview image of the digital slice, and an original magnification scanning map (103) is generated according to the size proportional relation of the digital slice and the tile image;
then, constructing an exclusive directory of the digital slice in a file system, storing metadata contents such as patient clinical information, tissue part information, slice scanning information and the like of the digital slice, and storing a preview image, a label image and a scanning map of the slice;
then, dividing the digital slice into a plurality of tile images with the same size according to the original multiplying power scanning map, and storing the tile images according to path information generated by a map projection transformation formula (104);
then, a plurality of low-magnification scanning maps (105) are generated according to the original-magnification scanning map by down-sampling, the digital slices are down-sampled according to the newly generated low-magnification scanning map and are divided into a plurality of tile images with the same size, and the tile images (106) are stored according to path information generated by a map projection transformation formula;
and browsing the digital slices, converting the digital slices into path information of the required tile image according to the initial longitude and latitude coordinates and the scale information, and reconstructing the digital slices according to the map coordinates (107).
In the method, the digital slice (101) can be acquired by any one of the following modes: the digital slice scanning device creates, parses an existing digital slice file, invokes a commercial digital slice system programming interface.
The manner in which the digital slice preview image (102) is acquired may be by any of the following: photographing the actual integral slice which exists physically; down-sampling from the digital slice; and calling a commercial digital slicing system programming interface to obtain the data.
As shown in fig. 2, 201 is a digital slice whole preview image obtained by photographing a physically existing actual whole slice in the present embodiment, and 202 is a digital slice whole preview image obtained by down-sampling a digital slice in the present embodiment. The digital slice preview image 202 is segmented into regions of interest to obtain organized regions on the digital slice. And generating a scanning map, wherein the organized area is 1, the unorganized background area is 0, and the area with the median value of 1 in the scanning map generates the tile image.
The size of the original magnification scanning map is determined by the following method: assuming that the width of the digital slice is W, the height of the digital slice is H, the width of the tile image is m-th power of 2, and the height of the tile image is n-th power of 2, the width W of the original magnification scanning map is W0＝ceil(W/2m) Height h of original magnification scan map0＝ceil(H/2n) Ceil is the smallest integer not less than a given value. m and n preferably have values of 7, 8, 9 and 10, and most preferably have values of m ═ n ═ 8. In fig. 2, if the pixel width of the digital slice is W40128, the pixel height of the digital slice is H96944, the width of the tile image is 256 (i.e., m 8), and the height of the tile image is 256 (i.e., n 8), the width W of the generated original magnification scan map 203 is W0157, height h0＝379。
Down-sampling generation is lowMagnification scan map (105): under different multiplying powers, the size of the scanning map is represented by multiplying power z, and the width of the z multiplying power scanning map
Height of z-magnification scan map
As shown in fig. 2: when z is 0, characterizing an original magnification scan map 203; when z is 1, the width w of the scan map 204 is 1-magnification179, height h1190; when z is 2, the width w of the scan map 205 is 2-fold2Height h 40295; when z is 3, the width w of the scan map 206 is 3-fold320, height h3＝48。
Under different multiplying powers, the size of the reconstructed digital slice is represented by the multiplying power z, and the width W of the reconstructed digital slicez＝wz×2mReconstructing the height H of the digital slicez＝hz×2n。
And (4) dividing the digital slice to generate and store tile images with different multiplying powers, and calculating a storage path for generating the tile images by using a map projection transformation formula. 104 and 106 is one of the following: mercator projection, gaussian-Kruger projection, universal transverse axis Mercator (UTM) projection, and Lambert equiangular (Lambert) projection. A preferred map projection transformation formula is the Mercator projection.
In this embodiment, the tile image path is composed of information such as the exclusive directory dir of the digital slice, the magnification z, the longitude mapping value lon, and the latitude mapping value lat.
In this embodiment, the longitude mapping value and the latitude mapping value are calculated by: describing the position of the tile image in the digital slice by using the pixel position (x, y) of the scan map corresponding to the magnification z, the longitude mapping value lon corresponding to x is:
the latitude mapping value lat corresponding to y is:
wherein Lo is a longitude value corresponding to the center of the digital slice, and La is a latitude value corresponding to the center of the digital slice; w is azWidth of the scanned map, h, corresponding to magnification zzThe height of the scanned map corresponding to the multiplying power z; ceil is the minimum integer not less than the given value, round is the rounding evaluation of the given value, floor is the minimum integer not more than the given value, log is the natural logarithm of the given value, tan is the tangent value of the given value, and cos is the cosine value of the given value; n is a positive integer, and the value is larger than the maximum value of the multiplying power z. The longitude map value lon and the latitude map value lat are calculated as integers.
In the embodiment of the invention, the adopted tile image path organization method comprises the following steps: and generating a corresponding magnification subdirectory according to the magnification z under the exclusive directory dir of the digital slice, generating a corresponding longitude subdirectory according to the longitude mapping value lon under the magnification subdirectory, and using the latitude mapping value lat as the file name of the tile image. For the tile image with the file suffix name of type, the corresponding path information is dir \ N-z \ lon \ lat. Suppose that the exclusive directory dir of a digital slice is "D: \ Slides \ 001", when N ═ 18, the longitude mapping value under 1 magnification is 65580, the latitude mapping value is 65636, and the image file suffix name is png, then the path corresponding to the tile image is "D: \ Slides \001\17\65580\65636. png".
Referring to fig. 3, a system for storing and browsing multiple-rate digital slice images according to an embodiment of the present invention includes:
the metadata read-write module 301: the method is used for writing and reading the metadata contents such as patient clinical information, tissue part information, slice scanning information and the like of the digital slice;
file directory management module 302: for the creation and management of a digital slice-specific directory, a corresponding tile image storage directory;
a longitude and latitude coordinate and image path analysis module 303: generating longitude and latitude coordinates and a file path for the tile image;
tile image read-write module 304: the tile image is stored and read according to the longitude and latitude coordinates and the file path generated by the image path analysis module;
scan map read/write module 305: down-sampling and segmenting from a global preview image of the digital slice, scanning positions for recording and reading tile images;
the tag image read-write module 306: for storage and reading of slice label images;
preview image reading and writing module 307: writing and reading of the slice whole preview image;
digital slice reconstruction and browsing module 308: automatically retrieving the required tile images according to the clinical information, the tissue part information, the slice scanning information and the image storage information of the patient of the digital slice, and arranging the tile images according to the longitude mapping value and the latitude mapping value in a browsing window to realize the reconstruction and the browsing of the digital slice;
file system 309: a file management system for managing and storing the above metadata file, tile image, preview image, scan map, label image.
In this embodiment, the digital slice reconstructing and browsing module 308 has a boundary composed of longitude and latitude coordinates, where the center longitude of the boundary is the longitude value Lo corresponding to the center of the digital slice, and the center latitude of the boundary is the latitude value La corresponding to the center of the digital slice. A preferred value is Lo ═ La ═ 0 °.
Referring to fig. 4, a browse window of the digital slice reconstruction and browse module 308 includes elements of a reconstructed slice image 401, a tab image 402, a preview navigation section 403, a magnification selection section 404, a scale section 405, slice copyright information 406, and the like. In the present embodiment, the label image 402, the preview navigation part 403, and the magnification selection part 404 float above the reconstructed slice image 401.
The tab image 402, the preview navigation part 403, the magnification selection part 404, and the scale part 405 may be dragged by using a mouse, or may be dragged by a finger or a touch pen when supported by a touch device. As shown in fig. 5, the manner of operation on a touch screen display device is given. The above elements have two states of display and hiding. The tag image 402 is in a display state, and clicking on the header portion of the tag image 402 brings the element into a hidden state. In the hidden state, a gesture button 501 is formed, and clicking the button 501 switches back to the display state. The tag image 402 and the preview navigation section 403 may be combined into one switchable function section when the positions overlap. When the label image 402 is dragged over the preview navigation feature 403, both will combine into one function switchable feature 502, and clicking on the icon switches the function.
The preview navigation part 403 has a viewing area box 503 thereon, and dragging the viewing area box 503 can control the contents displayed in the browse window. When the viewing area box 503 changes position, the viewing window will load a new set of tile images and generate a new reconstructed slice image 504. The display magnification of the current digital section can be selected by the magnification selection unit 404, and the display magnification is organized according to the magnification of a conventional biological microscope objective, and includes options of 40 times, 20 times, 10 times, 5 times, 2.5 times and the like, and also supports manual setting. The scale section 405 displays the relationship between the pixel size at the current display magnification and the physical size. When the magnification is switched, the scale and content of the scale component 405 will be updated. The slice copyright information 406 shows information on a digital slice creation unit and a software authoring unit.
The above-described embodiments are merely preferred embodiments of the present invention, which should not be construed as limiting the invention. Various changes and modifications may be made by one of ordinary skill in the pertinent art without departing from the spirit and scope of the present invention. Therefore, the technical scheme obtained by adopting the mode of equivalent replacement or equivalent transformation is within the protection scope of the invention.
Claims (10)
1. A method for storing and browsing multiple-rate digital slice images is characterized by comprising the following steps:
step 1: acquiring a digital slice, and acquiring a whole preview image of the digital slice;
step 2: dividing an organized part in the overall preview image of the digital slice and generating an original magnification scanning map;
and step 3: constructing an exclusive directory of the digital slice in a file system, and storing the metadata content of the digital slice: patient clinical information, tissue site information, slice scan information; saving the whole preview image, the label image and the original magnification scanning map of the slice;
and 4, step 4: dividing the digital slice into a plurality of tile images with the same size according to an original multiplying power scanning map, and storing the tile images according to path information generated by a map projection transformation formula;
and 5: the method comprises the steps of generating a plurality of low-magnification scanning maps according to original-magnification scanning map downsampling, downsampling a digital slice according to a newly generated low-magnification scanning map, dividing the digital slice into a plurality of tile images with the same size, and storing the tile images according to path information generated by a map projection transformation formula;
step 6: and browsing the digital slices, converting the digital slices into path information of the required tile image according to the initial longitude and latitude coordinates and the scale information, and reconstructing the digital slices according to the map coordinates.
2. The method for storing and browsing multiple-magnification digital slice images according to claim 1, wherein the digital slices obtained in step 1 are obtained by one of the following methods: the digital slice scanning device creates, parses an existing digital slice file, invokes a commercial digital slice system programming interface.
3. The method of claim 1, wherein the width of the digital slice is W, the height of the digital slice is H, the width of the tile image is m-th power of 2, and the height of the tile image is n-th power of 2, so that the width of the original magnification scanning map is W0＝ceil(W/2m) Height h of original magnification scan map0＝ceil(H/2n) (ii) a Under different multiplying powers, the size of the scanning map is represented by multiplying power z, and the width of the z multiplying power scanning map
Height of z-magnification scan map
m and n take the values of 7, 8, 9 and 10;
under different multiplying powers, the size of the reconstructed digital slice is represented by the multiplying power z, and the width W of the reconstructed digital slicez＝wz×2mReconstructing the height H of the digital slicez＝hz×2n。
4. The method of claim 3, wherein m and n are 8, ceil is the smallest integer no less than a given value.
5. The method for storing and browsing multiple-magnification digital slice images according to claim 3, wherein the map projection transformation formula adopted in step 4 is one of the following: mercator projection, gaussian-Kruger projection, universal transverse axis Mercator (UTM) projection, and Lambert equiangular (Lambert) projection.
6. The method for storing and browsing multiple-magnification digital slice images of claim 3, wherein the map projection transformation formula used in step 4 is Mercator projection.
7. The method of claim 3, wherein saving path information for tile images comprises: the exclusive directory dir of the digital slice, the multiplying factor z, the longitude mapping value lon and the latitude mapping value lat.
8. The method for storing and browsing the image of multiple-magnification digital slices as claimed in claim 7, wherein the longitude mapping value and the latitude mapping value are calculated by:
using pixel bits of scanned map corresponding to magnification zGiven (x, y) describes the location of the tile image in the digital slice, the longitude mapping value lon for x is:
the latitude mapping value lat corresponding to y is:
wherein Lo is a longitude value corresponding to the center of the digital slice, and La is a latitude value corresponding to the center of the digital slice; w is azWidth of the scanned map, h, corresponding to magnification zzThe height of the scanned map corresponding to the multiplying power z; ceil is the minimum integer not less than the given value, round is the rounding evaluation of the given value, floor is the minimum integer not more than the given value, log is the natural logarithm of the given value, tan is the tangent value of the given value, and cos is the cosine value of the given value; n is a positive integer, and the value is greater than the maximum value of the multiplying power z; the longitude map value lon and the latitude map value lat are calculated as integers.
9. The method for storing and browsing multiple-magnification digital slice images according to claim 3, wherein the path organization method for saving tile images is as follows:
generating a corresponding multiplying factor subdirectory under the exclusive directory dir of the digital slice according to the multiplying factor z, generating a corresponding longitude subdirectory under the multiplying factor subdirectory according to the longitude mapping value lon, and using the latitude mapping value lat as the file name of the tile image; for a tile image with a file suffix name of type, the corresponding path information is dir \ N-z \ lon \ lat.type, N is a positive integer, and the value is greater than the maximum value of the multiplying power z.
10. The system for storing and browsing the images of the multiple-magnification digital slices according to claim 1, comprising a metadata read-write module, a file directory management module, a scan map read-write module, a label image read-write module, a digital slice reconstruction and browsing module and a file system, specifically:
the metadata read-write module: writing and reading metadata of patient clinical information, tissue site information and slice scanning information for digital slices;
the file directory management module: for the creation and management of a digital slice-specific directory, a corresponding tile image storage directory;
a longitude and latitude coordinate and image path analysis module: generating longitude and latitude coordinates and a file path for the tile image;
the tile image reading and writing module: the tile image is stored and read according to the longitude and latitude coordinates and the file path generated by the image path analysis module;
a preview image reading and writing module: writing and reading of the slice whole preview image;
the map scanning read-write module: down-sampling and segmenting from a global preview image of the digital slice, scanning positions for recording and reading tile images;
a label image reading and writing module: for storage and reading of slice label images;
the digital slice reconstruction and browsing module comprises: automatically retrieving the required tile images according to the clinical information, the tissue part information, the slice scanning information and the image storage information of the patient of the digital slice, and arranging the tile images according to the longitude mapping value and the latitude mapping value in a browsing window to realize the reconstruction and the browsing of the digital slice; the digital slice reconstruction and browsing module is provided with a boundary composed of longitude and latitude coordinates, the center longitude of the boundary is a longitude value Lo corresponding to the center of the digital slice as claimed in claim 5, the center latitude of the boundary is a latitude value La corresponding to the center of the digital slice, and the value is Lo-La-0 degrees;
and the file system is used for managing and storing the metadata, the tile images, the preview images, the scanning maps and the label images.
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| CN111785353B (en) * | 2020-06-29 | 2022-07-08 | 平安国际智慧城市科技股份有限公司 | Digital pathological section processing method and device, storage medium and electronic equipment |
| CN112466440B (en) * | 2020-12-08 | 2023-07-21 | 深圳平安智慧医健科技有限公司 | Medical image loading method and device, electronic equipment and storage medium |
| CN112927784B (en) * | 2021-03-16 | 2022-08-12 | 麦克奥迪(厦门)医疗大数据有限公司 | Pathological section browsing path recording method in digital pathological system |
| CN113342916B (en) * | 2021-06-22 | 2024-01-26 | 中煤航测遥感集团有限公司 | Geographic tag image file format data processing method and device and electronic equipment |
| CN113505254B (en) * | 2021-07-08 | 2024-01-23 | 山东志盈医学科技有限公司 | Method and device for efficiently storing digital slices by server |
| CN115410693B (en) * | 2022-11-01 | 2023-03-24 | 深圳市生强科技有限公司 | Storage system, browsing system and method for digital pathological section |
| CN115861140B (en) * | 2022-11-29 | 2024-02-02 | 交通运输部科学研究院 | Content missing tile replacement method and device, electronic equipment and storage medium |
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