CN104116831A - Swelling decreasing and pain relieving particle - Google Patents

Abstract

The invention relates to a swelling decreasing and pain relieving particle, which comprises the following components: 10-20g of peach kernel, 10-20g of radix rehmanniae, 10-25g of Japanese eupatorium, 10-20g of safflower, 10-20g of Chinese angelica, 5-15g of leech, 10-20g of radix paeoniae rubra, 10-20g of costus root, 10-20g of licorice, 10-20g of Ligusticum wallichii, and 10-20g of Green Tangerine Peel. With the efficacy of invigorating blood circulation and decreasing swelling, promoting Qi circulation and relieving pain, the swelling decreasing and pain relieving particle is suitable for early trauma, injured part swelling and pain, and has a good curative effect.

Description

A kind of reducing swelling and alleviating pain granule

Technical field

The invention belongs to medical technical field, be specifically related to a kind of reducing swelling and alleviating pain granule.

Background technology

At present, the medicine that is used for the treatment of wound swelling, pain symptom has a lot, wherein have ZHONGHUA DIEDA WAN with the immediate medicine of the present invention, its component comprises: Caulis et Folium hedyotis hedyotideae, Radix Piperis sarmentosi (Herba Piperis Sarmentosi), Herba Hyperici Japonici, Radix et Rhizoma Smilacis Ripariae, Herba Centipedae, Radix Achyranthis Bidentatae, the Radix Linderae, Radix seu Caulis Parabarii, GUIHUAFU, leaf of Radix Glycosmidis Citrifoliae, Herba Inulae cappae, Herba Artemisiae Anomalae, Caulis Bauhihiae Championii, Caulis et Folium Hyptidis suaveolentis, Radix Cudraniae, Radix Zanthoxyli, Caulis Spatholobi, Ramulus et Folium Claoxyli, Flos Ilicis Asprellae, Semen Momordicae, Radix Solani indici, lobelia sessilifolia, Radix Angelicae Pubescentis, Rhizoma Atractylodis, Semen Impatientis, Fructus Gardeniae grandiflorae, Radix Aconiti Preparata, Flos Caryophylli, Rhizoma Cyperi, kadsura root, Ramulus Cinnamomi, Camphora.Character: honeyed pill.This ingredient complexity, main effect is: the swollen clearly active hemostasia and promoting granulation blood circulation promoting and blood stasis dispelling of antalgic purpose and relaxing tendons is used for dampening the new and old stasis of blood of muscles and bones and suffers from wound hemorrhage rheumatism stasis of blood pain.

The shortcoming of this medicine is, cures mainly from the function of ZHONGHUA DIEDA WAN, comparatively comprehensive, does not embody the theory of the determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs of Chinese medicine treatment disease.According to traditional Chinese medical bone fracture theory, fracture, dislocation, the acute injury of tendon and muscle are all dialectical according to three phases.Mainly taking pain, swelling as main, controlling should reducing swelling and alleviating pain in early days.

Summary of the invention

In order to overcome above-mentioned the deficiencies in the prior art, the object of the present invention is to provide a kind of reducing swelling and alleviating pain granule, there is promoting blood circulation and detumescence, promoting the circulation of QI to relieve pain, are applicable to wound early stage, traumatic part swelling, the feature that pain is imitated.

To achieve these goals, the technical solution used in the present invention is: a kind of reducing swelling and alleviating pain granule, includes following component:

Semen Persicae 10-20g, Radix Rehmanniae 10-20g, Herba Lycopi 10-25g, Flos Carthami 10-20g, Radix Angelicae Sinensis 10-20g, Hirudo 5-15g, Radix Paeoniae Rubra 10-20g, Radix Aucklandiae 10-20g, Radix Glycyrrhizae 10-20g, Rhizoma Chuanxiong 10-20g, Pericarpium Citri Reticulatae Viride 10-20g.

Beneficial effect of the present invention:

Compared with prior art, the present invention is based on traumatic red and swollen heat pain illness main manifestations is traumatic part swelling pain symptom, according to traditional Chinese medical bone fracture theory, and three dialectical principles of phase of fracture, dislocation, the acute injury of tendon and muscle.Mainly taking pain, swelling as main, controlling should reducing swelling and alleviating pain in early days.Therefore reducing swelling and alleviating pain granule more meets the dialectical principle of orthopedics and traumatology of Chinese medicine.Reducing swelling and alleviating pain granule be the Li Shenghua of Gansu Provincial Hospital of Traditional Chinese Medicine professor through proved recipe, prescription of the present invention is letter sternly, effect work, Radix Angelicae Sinensis, Rhizoma Chuanxiong blood circulation promoting and blood stasis dispelling in component of the present invention, reducing swelling and alleviating pain, joins Semen Persicae, Flos Carthami and strengthens the power of its removing blood stasis with potent drugs blood, tissue regeneration promoting blood.Close Radix Notoginseng, strengthen clots absorbing, analgesia, detumescence effect.Treating blood disorders must first be regulated the flow of vital energy, and the capable blood of gas, therefore join Pericarpium Citri Reticulatae Viride, the Radix Aucklandiae, promoting QI to circulate and dispersing the agglomeration of the pathogens pain relieving, the auxiliary Radix Rehmanniae, Radix Paeoniae Rubra removing heat from blood repercussive.Damage early stage tissue place spasm pain, have the edema of oozing out pathological change, therefore join Herba Lycopi, dissipation carbuncle, reduces it and oozes out, and impels swelling to disappear, and all medicines share, and gathers altogether blood circulation promoting and blood stasis dispelling, the merit of reducing swelling and alleviating pain.Through clinical more than ten years experiences confirm to have definite curative effect, emphasis be applicable to fracture, dislocation, the acute injury of tendon and muscle in early days.Simultaneously, from the party's ingredients, in side, Radix Angelicae Sinensis, the Radix Aucklandiae are again Gansu genuine medicinal materials, thus the guarantee of maximum possible the quality of ingredients of reducing swelling and alleviating pain side.The relative dosage form of next, wound early stage patient is mainly taking pain and be wound local swelling as main, granule is with respect to honeyed pill, medicine absorbs and enters blood with liquid micromolecule amount, the absorption in accelerate gastrointestinal road as much as possible, can play the therapeutical effect to patient with speed faster, thereby improve the curative effect of medicine.In a word, reducing swelling and alleviating pain granule is from the principles of formulating prescriptions, drug screening, and indication is selected to be significantly superior to selected control drug, and clinical result of use is also very definite, is worthy to be popularized and protects.

Detailed description of the invention

Below in conjunction with specific embodiment, the present invention is described in further detail.

Embodiment 1

A kind of reducing swelling and alleviating pain granule, includes following component:

Semen Persicae 13-18g, Radix Rehmanniae 12-17g, Herba Lycopi 14-20g, Flos Carthami 15-18g, Radix Angelicae Sinensis 13-18g, Hirudo 8-12g, Radix Paeoniae Rubra 14-18g, Radix Aucklandiae 14-18g, Radix Glycyrrhizae 12-15g, Rhizoma Chuanxiong 14-18g, Pericarpium Citri Reticulatae Viride 14-18g.

Select the medicines such as Flos Carthami, Radix Angelicae Sinensis, Rhizoma Chuanxiong to be prepared into granule, oral administration gastrointestinal absorbs, and medicine absorbs and enters blood with liquid micromolecule amount, thereby has improved the curative effect of medicine.The clinical practice several years, there is good curative effect.

Embodiment 2

A kind of reducing swelling and alleviating pain granule, includes following component:

Semen Persicae 10g, Radix Rehmanniae 10g, Herba Lycopi 10g, Flos Carthami 10g, Radix Angelicae Sinensis 10g, Hirudo 5g, Radix Paeoniae Rubra 10g, Radix Aucklandiae 10g, Radix Glycyrrhizae 10g, Rhizoma Chuanxiong 10g, Pericarpium Citri Reticulatae Viride 10g.

Select the medicines such as Flos Carthami, Radix Angelicae Sinensis, Rhizoma Chuanxiong to be prepared into granule, oral administration gastrointestinal absorbs, and medicine absorbs and enters blood with liquid micromolecule amount, thereby has improved the curative effect of medicine.The clinical practice several years, there is good curative effect.

Embodiment 3

A kind of reducing swelling and alleviating pain granule, includes following component:

Semen Persicae 20g, Radix Rehmanniae 20g, Herba Lycopi 25g, Flos Carthami 20g, Radix Angelicae Sinensis 20g, Hirudo 15g, Radix Paeoniae Rubra 20g, Radix Aucklandiae 20g, Radix Glycyrrhizae 20g, Rhizoma Chuanxiong 20g, Pericarpium Citri Reticulatae Viride 20g.

Select the medicines such as Flos Carthami, Radix Angelicae Sinensis, Rhizoma Chuanxiong to be prepared into granule, oral administration gastrointestinal absorbs, and medicine absorbs and enters blood with liquid micromolecule amount, thereby has improved the curative effect of medicine.The clinical practice several years, there is good curative effect.

Embodiment 4

A kind of reducing swelling and alleviating pain granule, includes following component:

Semen Persicae 15g, Radix Rehmanniae 15g, Herba Lycopi 20g, Flos Carthami 15g, Radix Angelicae Sinensis 15g, Hirudo 10g, Radix Paeoniae Rubra 15g, Radix Aucklandiae 15g, Radix Glycyrrhizae 15g, Rhizoma Chuanxiong 15g, Pericarpium Citri Reticulatae Viride 15g.

Select the medicines such as Flos Carthami, Radix Angelicae Sinensis, Rhizoma Chuanxiong to be prepared into granule, oral administration gastrointestinal absorbs, and medicine absorbs and enters blood with liquid micromolecule amount, thereby has improved the curative effect of medicine.The clinical practice several years, there is good curative effect.

Please provide pharmacological evaluation of the present invention

Radix Angelicae Sinensis, Rhizoma Chuanxiong blood circulation promoting and blood stasis dispelling in reducing swelling and alleviating pain granule side, reducing swelling and alleviating pain, joins Semen Persicae, Flos Carthami is strengthened its removing blood stasis with potent drugs blood, the power of tissue regeneration promoting blood.Close Radix Notoginseng, strengthen clots absorbing, analgesia, detumescence effect.Treating blood disorders must first be regulated the flow of vital energy, and the capable blood of gas, therefore join Pericarpium Citri Reticulatae Viride, the Radix Aucklandiae, promoting QI to circulate and dispersing the agglomeration of the pathogens pain relieving, the auxiliary Radix Rehmanniae, Radix Paeoniae Rubra removing heat from blood repercussive.Damage is organized in early days in spasm pain, has the edema of oozing out pathological change, therefore join Herba Lycopi, dissipation carbuncle, reduces it and ooze out, and impels swelling to disappear, and all medicines share, and gathers altogether blood circulation promoting and blood stasis dispelling, and the merit of reducing swelling and alleviating pain is used for the treatment of early stage swelling of limb and aches and have good therapeutic effect.

1.1 case selections: 146 examples are all standard by the guideline of clinical investigations of new Chinese medicine treatment trauma gall, include in and the equal conformance with standard of Excluded cases.Be divided at random 2 groups, treatment group adopts the treatment of reducing swelling and alleviating pain side, and matched group is treated by ZHONGHUA DIEDA WAN.

1.2 physical data: treatment group 94 examples, male 66 examples, female's 28 examples; 25～72 years old age, average 48.5 years old.80 examples of fracturing, dislocation and soft tissue injury 14 examples, be direct violence wound, and limb swelling is obvious.Matched group 52 examples, male 37 examples, female's 15 examples, 24～70 years old age, average 47 years old.Two groups of clinical datas are learned processing by statistics, without significant difference (P > 0.05), have comparability.

1.3 Therapeutic Method: treatment group gives reducing swelling and alleviating pain side, oral, the 50ml that is grown up a time, 2 times on the one, take half an hour after meal, child reduces by half, and can put on the skin outward if desired.Within 4 days, be a course for the treatment of, treat altogether 1～2 course for the treatment of, finish rear observed and recorded the course for the treatment of and sum up, during treatment, do not use other medicines.The oral ZHONGHUA DIEDA WAN of matched group (Guangxi × × pharmacy Group Plc, 6 balls/box), 1 ball, 2 times on the one.The same treatment group of the course for the treatment of and observed and recorded.

1.4 criterions of therapeutical effect: clinical cure: take medicine below 4 days, swelling is disappeared, pain disappears.Effective: take medicine 4 days, swelling is disappeared, pain disappears.Effective: take medicine 6～10 days, swelling is disappeared, pain disappears.Invalid: take medicine more than 10 days, swelling, pain symptom are without obvious alleviation.

1.5 therapeutic outcomes: clinical general curative effect after treatment, in table 1.

The clinical general curative effect of table 1

Toxicological experiment of the present invention

Said preparation prescription composition is the conventional variety that pharmacopeia is recorded, and not containing toxicity Chinese crude drug, simultaneously also without incompatibility, so find in the time carrying out the anxious slow poison experiment of animal, the reducing swelling and alleviating pain side that animal takes prescribed limit dosage is safe.

Immunization experiment of the present invention

Said preparation prescription composition is the conventional variety that pharmacopeia is recorded, and not containing toxicity Chinese crude drug, simultaneously also without incompatibility, so find in the time carrying out animal immune experiment, the reducing swelling and alleviating pain side that animal takes prescribed limit dosage is safe.

Claims (5)

1. a reducing swelling and alleviating pain granule, is characterized in that, includes following component:

Semen Persicae 10-20g, Radix Rehmanniae 10-20g, Herba Lycopi 10-25g, Flos Carthami 10-20g, Radix Angelicae Sinensis 10-20g, Hirudo 5-15g, Radix Paeoniae Rubra 10-20g, Radix Aucklandiae 10-20g, Radix Glycyrrhizae 10-20g, Rhizoma Chuanxiong 10-20g, Pericarpium Citri Reticulatae Viride 10-20g.

2. a kind of reducing swelling and alleviating pain granule according to claim 1, is characterized in that, includes following component:

Semen Persicae 13-18g, Radix Rehmanniae 12-17g, Herba Lycopi 14-20g, Flos Carthami 15-18g, Radix Angelicae Sinensis 13-18g, Hirudo 8-12g, Radix Paeoniae Rubra 14-18g, Radix Aucklandiae 14-18g, Radix Glycyrrhizae 12-15g, Rhizoma Chuanxiong 14-18g, Pericarpium Citri Reticulatae Viride 14-18g.

3. a kind of reducing swelling and alleviating pain granule according to claim 1, is characterized in that, includes following component:

Semen Persicae 10g, Radix Rehmanniae 10g, Herba Lycopi 10g, Flos Carthami 10g, Radix Angelicae Sinensis 10g, Hirudo 5g, Radix Paeoniae Rubra 10g, Radix Aucklandiae 10g, Radix Glycyrrhizae 10g, Rhizoma Chuanxiong 10g, Pericarpium Citri Reticulatae Viride 10g.

4. a kind of reducing swelling and alleviating pain granule according to claim 1, is characterized in that, includes following component:

Semen Persicae 20g, Radix Rehmanniae 20g, Herba Lycopi 25g, Flos Carthami 20g, Radix Angelicae Sinensis 20g, Hirudo 15g, Radix Paeoniae Rubra 20g, Radix Aucklandiae 20g, Radix Glycyrrhizae 20g, Rhizoma Chuanxiong 20g, Pericarpium Citri Reticulatae Viride 20g.

5. a kind of reducing swelling and alleviating pain granule according to claim 1, is characterized in that, includes following component:

Semen Persicae 15g, Radix Rehmanniae 15g, Herba Lycopi 20g, Flos Carthami 15g, Radix Angelicae Sinensis 15g, Hirudo 10g, Radix Paeoniae Rubra 15g, Radix Aucklandiae 15g, Radix Glycyrrhizae 15g, Rhizoma Chuanxiong 15g, Pericarpium Citri Reticulatae Viride 15g.