CN104116760A - An oral liquid for treating enuresis - Google Patents
An oral liquid for treating enuresis Download PDFInfo
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- CN104116760A CN104116760A CN201410332767.4A CN201410332767A CN104116760A CN 104116760 A CN104116760 A CN 104116760A CN 201410332767 A CN201410332767 A CN 201410332767A CN 104116760 A CN104116760 A CN 104116760A
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- oral liquid
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Abstract
The invention discloses an oral liquid for treating enuresis, and belongs to the technical field of medicines. The enuresis is commonly known as bed-wetting, and usually relates to involuntary urination of children during deep sleeping. At present, the enuresis is usually treated by behavior therapy and drug therapy. The oral liquid mainly comprises following raw materials by weight: 1-3 parts of chicken's gizzard-skin and 1-3 parts of mantis egg-case. The oral liquid is prepared by steps of: adding the chicken's gizzard-skin and the mantis egg-case into 3-5 times of water, dipping for 30-60 min, heating to 100 DEG C, extracting for 30-60 min, repeating extraction for one time, combining two extraction liquids, filtering to obtain a filtrate, concentrating the filtrate until the relative density at 60 DEG C is 1.10-1.15 to obtain a concentrated liquid, keeping the concentrated liquid for further use, adding water into the concentrated liquid, heating to boil the concentrated liquid, and burdening to obtain the oral liquid with each milliliter of the medicine liquid containing 5-10 g of the crude drug. Through clinical application and testing for 100 cases, 83 cases are cured, symptoms of 15 cases are relieved, and the effective rate is 98%. According to the clinical testing results, the oral liquid has functions of astringing, inducing astringency, reinforcing kidney to strengthen yang, helping digestion, and tonifying the stomach, and is free of side effects and safe and reliable to use.
Description
Technical field
The present invention relates to a kind of oral liquid for the treatment of the enuresis, belong to medical technical field.
Background technology
The enuresis is commonly called as bed-wetting, is often referred to child and does not independently urinate when sleeping soundly, and during generally to 4 year old, 20% child has enuresis phenomenon to occur, and in the time of 10 years old, only has 5%, if occurred weekly more than twice, and continues to reach 6 months, is medically just called enuresis.Enuresis is divided into primary enuresis and secondary enuresis, and secondary enuresis is mainly by lower urinary tract obstruction, cystitis, and neuropathy causes that urinary dysfunction causes; The primary enuresis cause of disease is complicated, mainly contains following several reason: inherited genetic factors, psychological factor, environmental effect, body function sexually transmitted disease (STD) become impact.For above-mentioned several causes of disease, modern medicine generally adopts the behavior therapy and Drug therapy, for example imipramine, oxibutynin, ephedrine and Desmopressin.The traditional Chinese medical science thinks that bed-wetting is mainly relevant in deficiency of kidney-QI, deficiency of both the splenic and pulmonary QI, therefore can improve physical qualification from this respect, thereby nurse one's health by Chinese medicine the target that reaches treatment enuresis.
Summary of the invention
Technical problem to be solved by this invention is to provide a kind of oral liquid for the treatment of the enuresis, in order to treat the problem of the child at night enuresis.
The solution of above-mentioned technical problem is to have adopted following technical measures: a kind of oral liquid for the treatment of the enuresis, is mainly comprised of following weight parts raw material: Endothelium Corneum Gigeriae Galli 1-3 part, Ootheca Mantidis 1-3 part;
The present invention also provides a kind of preparation method for the treatment of the oral liquid of the enuresis:
(1) get Endothelium Corneum Gigeriae Galli, Ootheca Mantidis and add 3-5 times of water gaging to soak 30-60 minute, be heated to 100 ℃ and extract 30-60 minute, repeat to extract once, merging extracted twice liquid filters, obtain filtrate, it is 1.10-1.15 that filtrate is concentrated to 60 ℃ of heat survey relative densities, obtains concentrated solution standby;
(2) get concentrated solution and add water post-heating to the dosing of boiling, make to contain crude drug amount 3-5 gram in every milliliter of medicinal liquid, pack and get final product.
Endothelium Corneum Gigeriae Galli and Ootheca Mantidis used in the present invention all refer to the medical material being recorded in < < Chinese Pharmacopoeia > >.Endothelium Corneum Gigeriae Galli refers to the gizzard inwall of a chicken, and what the present invention was used is the parch processed product of Endothelium Corneum Gigeriae Galli, has promoting digestion and invigorating the stomach aid digestion, and convergence stops puckery effect.Ootheca Mantidis refers to the ootheca of the insecticides such as Mantidae insecticide Chinese mantid, southern mantis, wide abdomen Mantidis, has controlling nocturnal emission with astringent drugs reducing urination, the effect of reinforcing the kidney and supporting YANG.The infant of functional enuresis can be divided into deficiency of kidney-QI, deficiency of both the splenic and pulmonary QI, dampness-heat of the liver, disarmony between the heart and kidney several types, and the present invention utilizes Endothelium Corneum Gigeriae Galli and Ootheca Mantidis the kidney invigorating, convergence, astringent or styptic treatment for spontaneous sweating effect, can be well for the enuresis symptom of above-mentioned several types.
For verifying clinical effectiveness of the present invention, through Tieshan Special Region, Beihai military camp hospital, 100 routine patients have been carried out to clinical verification with the present invention, checking is reported as follows:
(1) clinical data: get clinical case 100 examples, male's infant 58 examples, women's infant 42 examples, patient age 4-10 year, infants ' parents narration, all has the clinical symptoms of the enuresis in nighttime sleep process.
(2) Therapeutic Method: use oral liquid of the present invention oral, day takes secondary, each 10--15 milliliter, six days is a course for the treatment of, observes in time systemic side effects after medication.
(3) observation of curative effect:
(a) criterion of therapeutical effect: medication is observed clinical symptoms one month after two courses for the treatment of.
Cure: in nighttime sleep process, enuresis phenomenon disappears completely.
Take a turn for the better: in nighttime sleep process, enuresis phenomenon reduces than number of times before not taking medicine, but still has generation.
Invalid: clinical symptoms and sign are without any improvement or increase the weight of.
(b) efficacy analysis: patient observes clinical symptoms one month after two courses for the treatment of of above-mentioned medication, carries out clinical examination, wherein clinical symptoms disappearance person's 83 examples completely; Clinical symptom relief person 15 examples, clinical symptoms, without improver's 2 examples, is judged to be effective 98 examples, and effective percentage is 98%.Inefficiency is 2%; Side effect is observed: have no other untoward reaction.
(4) conclusion: from above-mentioned Clinical results, the present invention has the effect of astringent or styptic treatment for spontaneous sweating, the reinforcing the kidney and supporting YANG of convergence, promoting digestion and invigorating the stomach.For children's's enuresis nocturna.The present invention is for oral administration, and day takes secondary, and each 10-15 milliliter, has obtained good clinical efficacy, and effective percentage reaches 98%, does not find part and systemic anaphylaxis phenomenon, drug safety during medication.
The specific embodiment
Embodiment 1
(1) get each 10 kilograms of Endothelium Corneum Gigeriae Galli, Ootheca Mantidiss, add double centner water soaking 30-60 minute, be heated to 100 ℃ and extract 30-60 minute, repeat to extract once, merge extracted twice liquid and filter, obtain filtrate, it is 1.10 that filtrate is concentrated to 60 ℃ of heat survey relative densities, obtains concentrated solution standby;
(2) get concentrated solution and add water post-heating to the dosing of boiling, make to contain crude drug amount 5-10 gram in every milliliter of medicinal liquid, pack and get final product.
Embodiment 2
(1) get 10 kilograms of Endothelium Corneum Gigeriae Galli, 30 kilograms of Ootheca Mantidiss, add 120 kg water to soak 30-60 minute, be heated to 100 ℃ and extract 30-60 minute, repeat to extract once, merge extracted twice liquid and filter, obtain filtrate, it is 1.15 that filtrate is concentrated to 60 ℃ of heat survey relative densities, obtains concentrated solution standby;
(2) get concentrated solution and add water post-heating to the dosing of boiling, make to contain crude drug amount 5-10 gram in every milliliter of medicinal liquid, pack and get final product.
Embodiment 3
(1) get 30 kilograms of Endothelium Corneum Gigeriae Galli, 10 kilograms of Ootheca Mantidiss, add 120 kg water to soak 30-60 minute, be heated to 100 ℃ and extract 30-60 minute, repeat to extract once, merge extracted twice liquid and filter, obtain filtrate, it is 1.15 that filtrate is concentrated to 60 ℃ of heat survey relative densities, obtains concentrated solution standby;
(2) get concentrated solution and add water post-heating to the dosing of boiling, make to contain crude drug amount 5-10 gram in every milliliter of medicinal liquid, pack and get final product.
Claims (1)
1. treat an oral liquid for the enuresis, it is characterized in that described oral liquid is mainly comprised of following weight parts raw material: Endothelium Corneum Gigeriae Galli 1-3, Ootheca Mantidis 1-3;
The preparation method of the oral liquid of the described treatment enuresis is:
(1) get Endothelium Corneum Gigeriae Galli, Ootheca Mantidis and add 3-5 times of water gaging to soak 30-60 minute, be heated to 100 ℃ and extract 30-60 minute, repeat to extract once, merging extracted twice liquid filters, obtain filtrate, it is 1.10-1.15 that filtrate is concentrated to 60 ℃ of heat survey relative densities, obtains concentrated solution standby;
(2) get concentrated solution and add water post-heating to the dosing of boiling, make to contain crude drug amount 5-10 gram in every milliliter of medicinal liquid, pack and get final product.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410332767.4A CN104116760A (en) | 2014-07-14 | 2014-07-14 | An oral liquid for treating enuresis |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410332767.4A CN104116760A (en) | 2014-07-14 | 2014-07-14 | An oral liquid for treating enuresis |
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| CN104116760A true CN104116760A (en) | 2014-10-29 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201410332767.4A Pending CN104116760A (en) | 2014-07-14 | 2014-07-14 | An oral liquid for treating enuresis |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1996023492A1 (en) * | 1995-01-31 | 1996-08-08 | Sepracor, Inc. | Treating urinary incontinence using (s)-oxybutynin and (s)-desethyloxybutynin |
| CN1907298A (en) * | 2006-08-02 | 2007-02-07 | 胡彩芳 | Pill for treating polyuria and its preparing process |
-
2014
- 2014-07-14 CN CN201410332767.4A patent/CN104116760A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1996023492A1 (en) * | 1995-01-31 | 1996-08-08 | Sepracor, Inc. | Treating urinary incontinence using (s)-oxybutynin and (s)-desethyloxybutynin |
| CN1907298A (en) * | 2006-08-02 | 2007-02-07 | 胡彩芳 | Pill for treating polyuria and its preparing process |
Non-Patent Citations (4)
| Title |
|---|
| 刘启廷: "《健康的诀窍-有病早知早治的妙法》", 30 April 2013, 中医古籍出版社 * |
| 王希琳: "《常用中药及配伍手册》", 31 July 2002, 内蒙古科学技术出版社 * |
| 辽宁中医学院革命委员会: "《辽宁常用中草药手册》", 30 April 1970, 辽宁省新华书店 * |
| 邓修: "《中药制药工程与技术》", 31 May 2008, 华东理工大学出版社 * |
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Application publication date: 20141029 |