CN104056173A - 一种治疗孕妇妊娠期气血两亏的中药组合物 - Google Patents
一种治疗孕妇妊娠期气血两亏的中药组合物 Download PDFInfo
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- CN104056173A CN104056173A CN201410309519.8A CN201410309519A CN104056173A CN 104056173 A CN104056173 A CN 104056173A CN 201410309519 A CN201410309519 A CN 201410309519A CN 104056173 A CN104056173 A CN 104056173A
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- VZCYOOQTPOCHFL-OWOJBTEDSA-N (E)-but-2-enedioate;hydron Chemical compound 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- IQVQXVFMNOFTMU-FLIBITNWSA-N (Z)-ligustilide Chemical class 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Abstract
本发明涉及一种治疗孕妇妊娠期气血两亏的中药组合物，所述药物包括当归、熟地、人参、砂仁、续断、杜仲、艾叶、地榆、阿胶、白扁豆十位中药，本发明具有补气益血、宁血安胎、健脾养血，疏风清热、调经补肾、育阴补肝等功效，服用后药物主从脾、肝、肺经肾，治病与安胎并举，因病而致胎不安者，重在治病，病去则胎自安；因胎不安而致病者，重在安胎，胎安则病自愈，标本兼治，从根本上解决孕妇妊娠期气血两亏引起的妊娠腹痛、胎漏、胎动不安、滑胎、胎萎不长、胎水肿满、妊娠肿胀、妊娠心烦、妊娠眩晕、妊娠小便淋痛等症状，使呼吸系统、血液循环系统、神经系统、消化系统、泌尿系统恢复自我调节的功能，最终实现对孕妇妊娠期气血两亏的治疗。
Description
技术领域
[0001] 本发明属中药领域，具体的说是一种治疗孕妇妊娠期气血两亏的中药组合物。 一种治疗孕妇妊娠期气血两亏的中药组合物
背景技术
[0002] 目前，孕妇妊娠期气血两亏不但影响孕妇的健康，还可妨碍胎儿的正常发育，甚至 造成堕胎、小产。临床常见的孕妇妊娠期气血两亏症状有妊娠腹痛、异位妊娠、胎漏、胎动不 安、滑胎、胎死不下、胎萎不长、鬼胎、胎水肿满、妊娠肿胀、妊娠心烦、妊娠眩晕、妊娠痫证、 妊娠小便淋痛等。孕妇妊娠期气血两亏发病原因不外乎外感、情志内伤以及劳逸过度、房事 不节、跌仆闪挫等。其发病机理可概括为四个方面：其一，由于阴血下注冲任以养胎，出现阴 血聚于下，阳气浮于上，甚者气机逆乱，阳气偏亢的状态，易致妊娠恶阻、妊娠心烦、妊娠眩 晕、妊娠痫证等；其二，由于胎体渐长.致使气帆升降失润，又易形成气滞湿郁，痰湿内停， 可致妊娠心烦、妊娠肿胀、胎水肿满等；其三，胞脉系于肾，肾主藏精而关乎生殖，因此肾气 亏损，则胎元不固，易致胎动不安、滑胎等；其四，脾胃为气血生化之源，而胎赖血养，若脾虚 血少，胎失所养，可致胎漏、胎动不安、胎萎不长等。
[0003] 孕妇妊娠期气血两亏是虚证，治疗原则是治病与安胎并举。因病而致胎不安者，当 重在治病，病去则胎自安；因胎不安而致病者，应重在安胎，胎安则病自愈。具体治疗法有 三：补肾，目的在于固胎之本，用药以补肾益阴为主；健脾，目的在于益血之源，用药以健脾 养血为主；疏肝，目的在于通调气机，用药以理气清热为主。怀孕期间不易随便用药，以免伤 害胎儿，而中药既可以食用又可以药用，又没有副作用，非常适合虚证的补益。故从中医的 角度对孕妇妊娠期气血两亏进行治疗和调养是当前有效且可行的治疗方法之一。
发明内容
[0004] 本发明要解决的问题是针对以上问题，提供一种治愈率高、稳定效果好、标本兼治 的治疗孕妇妊娠期气血两亏的中药组合物。
[0005] 为解决上述问题，本发明所采用的技术方案是：
[0006] -种治疗孕妇妊娠期气血两亏的中药组合物，其特征在于：所述中药组合物由以 下重量份的中药原材料组成：
[0007] 当归20-30克、熟地20-30克、人参10-20克、砂仁10-20克、续断10-20克、杜仲 10-20克、艾叶10-20克、地榆10-20克、阿胶5-10克、白扁豆5-10克。
[0008] 作为一种优化方案：
[0009] 所述中药组合物由以下重量份的中药原材料组成：
[0010] 当归30克、熟地20克、人参15克、砂仁10克、续断20克、杜仲20克、艾叶10克、 地榆15克、阿胶10克、白扁豆5克。
[0011] 作为一种优化方案：
[0012] 所述中药组合物由以下重量份的中药原材料组成：
[0013] 当归30克、熟地25克、人参20克、砂仁10克、续断10克、杜仲15克、艾叶15克、 地榆15克、阿胶5克、白扁豆10克。
[0014] 作为一种优化方案：
[0015] 所述中药组合物由以下重量份的中药原材料组成：
[0016] 当归25克、熟地30克、人参15克、砂仁10克、续断20克、杜仲20克、艾叶15克、 地榆10克、阿胶10克、白扁豆5克。
[0017] 其中：
[0018] 当归味甘，性温，归心、肝、肺经，当归的化学成分主要包括藁本内酯类及其异构 物、香豆素类、多糖类、黄酮类及有机酸类等，具有补血、活血、调经、止痛、润燥、滑肠等功 效，主要用于血虚诸证、月经不调、经闭、痛经、症瘕结聚、崩漏、虚寒腹痛、痿痹、肌肤麻木、 肠燥便难、赤痢后重、痈疽疮疡等症状的治疗，当归为良好的补血药，故用于因血虚引起的 各种证候。
[0019] 熟地味甘，性温，归肝、肾经，具有补血、养阴、填精、益髓、健脾、养血、养阴补肾的 功效，用于治疗治疗血虚萎黄、眩晕、心悸、失眠及月经不调、崩中漏下、血虚出血证等症状。 熟地的药理作用：对骨髓造血系统的影响、对血液凝固的影响、对免疫系统的影响及抗氧化 作用。
[0020] 人参的肉质根为著名强壮滋补药，适用于调整血压、恢复心脏功能、神经衰弱及身 体虚弱等症，也有祛痰、健胃、利尿、兴奋等症。主要功效有补元气、复脉固脱、补脾益肺、生 津止渴、安神益智。主治妇女崩漏、劳伤虚损、食少、倦怠、反胃吐食、大便滑泄、虚咳喘促、自 汗暴脱、惊悸、健忘、眩晕头痛、阳痿、尿频、消渴、一切气血津液不足之症。
[0021] 砂仁味辛，性温，归脾、胃、肾经，具有温暖脾肾、下气止痛、宽胸膈、疏气滞、除呕 逆、增食欲、止冷泻、化滞、化湿开胃、补气养血、温脾止泻、宁血安胎等功效，用于湿浊中阻、 脘痞不饥、脾胃虚寒、呕吐泄泻、妊娠恶阻、胎动不安等症的治疗。
[0022] 续断味苦，性微温，归肝、肾经，具有补肝肾、强筋骨、调血脉、续折伤的功效，主要 用于胎漏、崩漏、带下、遗精、跌打损伤、腰背酸痛、足膝无力、金疮、痔漏、痈疽疮肿等症状的 治疗。
[0023] 杜仲味甘，性温，具有育阴补肝、调经补肾、壮腰膝、强筋骨、安胎的功效。杜仲对免 疫系统、内分泌系统、中枢神经系统、循环系统和泌尿系统都有不同程度的调节作用，杜仲 能兴奋垂体-肾上腺皮质系统，增强肾上腺皮质功能。可用于治疗胎漏欲堕、胎动不安、肝 肾风虚气弱、脚膝不可践地、腰脊疼痛、风毒流注下经、脾肾阳虚泄泻等症状。
[0024] 艾叶味辛、苦，性温，无毒；归脾、肝、肾经；芳香温散，具有温经、理气血、止血、安 胎、散寒、止痛，降湿、杀虫的功效，主治妊娠下血、月经不调、痛经、宫寒不孕、胎动不安、心 腹冷痛、吐血、衄血、咯血、便血、崩漏、泄泻久痢、带下、湿疹、疥癣、痈肿、痔疮。适用于虚寒 性出血及腹痛，对于妇女虚寒月经不调、腹痛、崩漏有明显疗效，是一种妇科良药。
[0025] 地榆味苦酸，性寒，无毒；归肝、肺、肾和大肠经。有凉血、止血、清热、疏风、解毒、培 清养阴、消肿敛疮等功效。主治崩漏、产前后诸血疾、吐血、咯血、衄血、尿血、便血、痔血、血 痢、赤白带下、疮痈肿痛、湿疹、阴痒、水火烫伤、月经不止、血痢不止、大便下血等症。
[0026] 阿胶是传统的滋补上品、补血圣药，味甘平，入肺、肝、肾经，具有补血、止血、补气 益血、育阴补肝、滋阴润燥等功效，长期服用可补血养血、美白养颜、抗衰老、抗疲劳、提高免 疫力，用于血虚萎黄、眩晕心悸、心烦不眠、肺燥咳嗽等症的治疗。
[0027] 白扁豆味甘，性微温，。归脾、胃经，有健脾、化湿、利尿、消肿、清肝、明目等功效，用 于脾胃虚弱、食欲不振、大便溏泻、白带过多、暑湿吐泻、胸闷腹胀、脾虚泄泻等症。
[0028] 本发明中的每味中药之间，通过数次临床配方后得出，其制作方法简单，可以根据 需要制作成片剂、丸剂、散剂或口服液等剂型，本发明的药物具有补气益血、宁血安胎、健脾 养血，疏风清热、调经补肾、育阴补肝等功效，服用后药物主从脾、肝、肺经肾，治病与安胎并 举，因病而致胎不安者，当重在治病，病去则胎自安；因胎不安而致病者，应重在安胎，胎安 则病自愈，标本兼治，从根本上解决孕妇妊娠期因气血两亏引起的妊娠腹痛、异位妊娠、胎 漏、胎动不安、滑胎、胎死不下、胎萎不长、鬼胎、胎水肿满、妊娠肿胀、妊娠心烦、妊娠眩晕、 妊娠痫证、妊娠小便淋痛等症状，使呼吸系统、血液循环系统、神经系统、消化系统、泌尿系 统恢复自我调节的功能，最终实现对孕妇妊娠期气血两亏的治疗。
[0029] 本发明的制作方法：
[0030] 将上述中药按重量份混合后，加水煎煮半个小时，滤除药渣，即得口服液。如需制 作片剂、散剂、丸剂或胶囊可将上述中药按重量份混合后粉碎成末，制成片剂、散剂、丸剂或 胶囊。
[0031] 服用方法：每日一剂，每天三次，饭前服用，五天为一个疗程。
[0032] 本发明根据上述中药的药理，以及数次的临床试验，对轻、中、重度妊娠期气血两 亏患者均具有明显的治疗效果。
[0033] 为进一步考察本发明药物的临床疗效和安全性，我们选择了 280例妊娠期气血两 亏患者对本发明药物的治疗疗效进行临床试验。
[0034] 将280例妊娠期气血两亏患者随机分为两组，每组140例患者。对照组中，年龄 20〜30岁94例，30〜40岁46例，病程一至二个月；治疗组中，年龄20〜30岁92例，30〜 40岁48例，病程二至四个月。
[0035] 两组病例在年龄、病程等方面经统计学分析，具有可比性。所有病例均参照《内科 学》中妊娠期气血两亏的诊断标准进行诊断。
[0036] 对照组采用适当运动，合理膳食，并口服富马酸25mg，每日三次；治疗组口服本发 明药物煎后口服溶液，一日一剂，一日三次。
[0037] 疗效标准：
[0038] 治愈--体征正常，无妊娠腹痛、胎动不安、胎水肿满、妊娠心烦、妊娠眩晕等症 状，饮食、睡眠正常；
[0039] 显效--体征正常，偶有伴有胎动不安、妊娠心烦、妊娠眩晕等症状，饮食、睡眠正 常；
[0040] 有效一经常出现胎动不安、妊娠心烦、妊娠眩晕等症状，饮食、睡眠正常；
[0041] 无效--胎动不安、妊娠心烦、妊娠眩晕等症状一直没消失，不思饮食，睡眠质量 差。
[0042] 表一
[0043] 组别 例数治愈n(% )显效n(% )有效n(% )无效n(% ) 总有效率n(%) 对照组 140 60(42.0)~115(82. 1)~ 125(89.3) 15(10.7) 125(89. 3)
Claims (4)
1. 一种治疗孕妇妊娠期气血两亏的中药组合物，其特征在于：所述中药组合物由以下 重量份的中药原材料组成： 当归20-30克、熟地20-30克、人参10-20克、砂仁10-20克、续断10-20克、杜仲10-20 克、艾叶10-20克、地榆10-20克、阿胶5-10克、白扁豆5-10克。
2. 根据权利要求1所述的治疗孕妇妊娠期气血两亏的中药组合物，其特征在于：所述 中药组合物由以下重量份的中药原材料组成： 当归30克、熟地20克、人参15克、砂仁10克、续断20克、杜仲20克、艾叶10克、地榆 15克、阿胶10克、白扁豆5克。
3. 根据权利要求1所述的治疗孕妇妊娠期气血两亏的中药组合物，其特征在于：所述 中药组合物由以下重量份的中药原材料组成： 当归30克、熟地25克、人参20克、砂仁10克、续断10克、杜仲15克、艾叶15克、地榆 15克、阿胶5克、白扁豆10克。
4. 根据权利要求1所述的治疗孕妇妊娠期气血两亏的中药组合物，其特征在于：所述 中药组合物由以下重量份的中药原材料组成： 当归25克、熟地30克、人参15克、砂仁10克、续断20克、杜仲20克、艾叶15克、地榆 10克、阿胶10克、白扁豆5克。
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Application publication date: 20140924 |