CN104056129A - Traditional Chinese medicine combination for treating colibacillosis of minks - Google Patents

Traditional Chinese medicine combination for treating colibacillosis of minks Download PDF

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Publication number
CN104056129A
CN104056129A CN201410337658.1A CN201410337658A CN104056129A CN 104056129 A CN104056129 A CN 104056129A CN 201410337658 A CN201410337658 A CN 201410337658A CN 104056129 A CN104056129 A CN 104056129A
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CN
China
Prior art keywords
chinese medicine
parts
traditional chinese
mink
colibacillosis
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Pending
Application number
CN201410337658.1A
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Chinese (zh)
Inventor
朱展
杨永贵
梁宝玉
陶永侠
李翠
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YANTAI HAIYAN PHARMA CO Ltd
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YANTAI HAIYAN PHARMA CO Ltd
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Priority to CN201410337658.1A priority Critical patent/CN104056129A/en
Publication of CN104056129A publication Critical patent/CN104056129A/en
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    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

The invention relates to a traditional Chinese medicine combination for treating colibacillosis of minks, which belongs to the field of traditional Chinese medicines. The traditional Chinese medicine combination is prepared from the following raw materials in parts by weight: 35-45 parts of pear carbon, 5-15 parts of coptis chinensis, 25-35 parts of scorched hawthorn fruit and 5-15 parts of barley malt. According to the traditional Chinese medicine combination disclosed by the invention, pear carbon and scorched hawthorn fruit are capable of resisting bacteria and relieving dysentery; coptis chinensis is capable of resisting bacteria and eliminating dampness; barley malt is capable of helping digestion and regulating qi; the four medicines are compatible, and the whole formula is capable of treating both symptoms and root causes, strengthening body resistance and eliminating evil, comprehensively adjusting, and balancing yin and yang; the various medicines are compatible to achieve the functions of resisting bacteria and relieving dysentery, and improving digestion, capable of adjusting the qi and blood running in the body, and capable of rapidly relieving symptoms such as pain, and recovering appetite and digestion function; and during application, the medicine disclosed by the invention is taken by 0.5 g per kilogram of body weight, and clinical tests prove that the cure rate achieves more than 90%, and the medicine is unique in curative effect.

Description

The Chinese medicine composition for the treatment of mink colibacillosis
Technical field
The invention belongs to the field of Chinese medicines, relate to particularly a kind of Chinese medicine composition for the treatment of mink colibacillosis.
Background technology
Colibacillosis is a kind of acute infectious disease, by escherichia coli, is caused.Primary disease mostly is spontaneous infection, i.e. the breeding rapidly when mink Abwehrkraft des Koepers declines of escherichia coli in intestinal, produces virulence, causes and causes a disease.Children ermine is not well established because of digestive system development, and resistance is not strong, adds that food nutrition health is not good enough, is easy to suffer from this disease.
Mink infects the primary disease initial stage, and loss of appetite is listless, fervescence, asoscope is dry, soft yellow or the Lycoperdon polymorphum Vitt of being of loose and watery stool, then there is dysentery, watery diarrhea, myasthenia of limbs, has a delicate constitution, the back of a bow of bending over, around fecal pollution is serious for anus, suddenly heavily suffers from death in ermine 2-3 days, and chronic 5-6 days dead.In order to strengthen the premunition of young ermine, in age of sucking, in female ermine daily ration, to note adding antibiotic, to the young ermine after wean, feed a break time high-quality full price of (about 20 days), digestible feedstuff.Meanwhile, feed structure can not change suddenly, with progressively adjust be adapted to suitable.In addition, note the health of feedstuff, drinking-water, cell, apparatus, prevent colibacillary pollution, from source, prevent also very important.
Generally use now antibiotic therapy, it is slow that mink gastrointestinal bacterial flora recovers, and easily forms antibiotic remains.
Use separately at present western medicine, effect is also imprecise, cannot remove the toxin in body.By Western medicine intestinal microbial population balance, can not be adjusted fast separately, harmful bacteria and probiotics are killed simultaneously in a large number, cause digestive and absorptive functions to weaken, and antibiotic also has drug residue, and environment is also had to pollution.
Summary of the invention
The technical problem to be solved in the present invention is to provide the Chinese medicine composition that a kind of effective minimizing is residual, reduce toxic and side effects, reduce to pollute and treat safely and effectively mink colibacillosis.
The present invention is achieved through the following technical solutions:
Treat a Chinese medicine composition for mink colibacillosis, it is characterized in that it is to be made by following raw materials by weight portion: pear wood carbon 35-45 part, Rhizoma Coptidis 5-15 part, Fructus Crataegi (parched to brown) 25-35 part, Fructus Hordei Germinatus 5-15 part.
Described various raw material preferred weight umber is: 40 parts, pear wood carbon, 10 parts of Rhizoma Coptidis, 30 parts of Fructus Crataegi (parched to brown)s, 10 parts of Fructus Hordei Germinatus.
The granularity of described pear wood carbon, Rhizoma Coptidis, Fructus Crataegi (parched to brown), Fructus Hordei Germinatus is 20-200 order.
The consumption of described Chinese medicine composition is per kilogram of body weight 0.5g.
The characteristic of medicine is as follows:
Pear wood carbon: property is flat; Taste is micro-salty; Return spleen, lung meridian.The effect with lowering the adverse flow of QI, cures mainly QI-mass oppressive feeling and dizziness, fullness in the chest tachypnea, stagnation of QI cough with dyspnea.Modern study shows that pear wood carbon has obvious adsorption, can adsorb the toxin in gastrointestinal tract, also has obvious antibacterial action, can effectively improve flora environment and acid-base balance in intestinal.
Rhizoma Coptidis: bitter in the mouth, cold in nature, GUIXIN, stomach, liver, large intestine channel.Heat clearing and damp drying, eliminating fire and detoxication.For damp and hot feeling of fullness, vomiting acid regurgitation, dysentery, jaundice, unconsciousness due to high fever, hyperactivity of heart-fire, clearing stomach stomach function regulating preventing or arresting vomiting.For cold and heat, tie mutually damp and hot middle resistance, feeling of fullness vomiting.Modern study shows that Rhizoma Coptidis has following effect: 1. anti-ameba effect 5. antiinflammatories of antibacterial action 2. antifungic action 3. antivirus action 4., diarrhea effect 6. are on affect 12. antiulcer actions of Cardiovascular 7. refrigeration function 8. hypoglycemic activity 9. effect for reducing blood fat 10. antioxidations 11. on blood system.
Fructus Crataegi (parched to brown): sour in the mouth, sweet, slightly warm in nature.Return spleen, stomach, Liver Channel.Promoting digestion and invigorating the stomach, circulation of qi promoting dissipating blood stasis.For meat stagnation, gastral cavilty distension, dysentery stomachache, blood stasis amenorrhea, postpartum stagnation, trusted subordinate's twinge, hernia pain; Hyperlipemia.The effect of Fructus Crataegi (parched to brown) dyspepsia and intestinal stasis relieving strengthens.For meat stagnation, dysentery is not well.Modern study shows that Fructus Crataegi (parched to brown) can improve the concentration of gastrointestinal tract acid, the secretion of the enzyme that stimulates digestion.
Fructus Hordei Germinatus: sweet in the mouth, slightly warm in nature, return spleen, stomach, Liver Channel; Rise and can fall; There is promoting digestion and removing stagnation, the effect of soothing liver-QI galactopoiesis; Cure mainly food stagnation and do not disappear, distension and fullness in the abdomen, vomiting, has loose bowels, inappetence.Modern study shows that Fructus Hordei Germinatus contains multiple digestant enzyme, promotes food digestion to absorb.
The combination principle of Chinese medicine composition is " efficacy enhancing and toxicity reducing ", and therefore, the pharmacological action that the different medicine of compatibility embodies is also different.Said medicine compatibility, pear wood carbon, the antibacterial dysentery relieving of Fructus Crataegi (parched to brown), the antibacterial dampness of Rhizoma Coptidis, Fructus Hordei Germinatus help digestion and regulate the flow of vital energy, four medicines phases 5, full side is able to treating both the principal and secondary aspects of a disease, strengthening vital QI to eliminate pathogenic factors, across-the-board regulation, Yin Yang balancing.
Each medicine mutually 5, reaches antibacterial dysentery relieving jointly, the effect of invigorating the stomach and promoting digestion, and adjust QI-blood circulation in body, can fast pain relief etc. symptom, recover appetite and digestive function.
The invention has the beneficial effects as follows: the present invention is with antibacterial dysentery relieving, and invigorating the stomach and promoting digestion is the rule for the treatment of, reasonable recipe, preparation technology is simple, applied widely.The present invention adopts pure Chinese medicinal herbs to make, wide material sources, cost are low, cure rate is high, medicine noresidue, have no side effect, particularly after micronizing, destroy to greatest extent plant cell wall, solved the deficiency that Chinese medicine powder crude fiber content is high, effective ingredient is difficult to stripping, be easier to mink and absorb.Have significant antibacterial dysentery relieving, the effect of invigorating the stomach and promoting digestion and adjusting body function, effectively treats mink colibacillosis, shortens the period of convalescence.Easy to use.Clinical trial proves, cure rate reaches more than 90%, has unique curative effect.
The specific embodiment
Below in conjunction with preferred embodiment, to according to the specific embodiment provided by the invention, details are as follows:
Embodiment 1
By crossing 200 mesh sieves after the various raw material pulverizing in prescription, take pear wood carbon 450g, Rhizoma Coptidis 150g, Fructus Crataegi (parched to brown) 350g, Fructus Hordei Germinatus 150g, mix homogeneously.
Embodiment 2
By crossing 100 mesh sieves after the various raw material pulverizing in prescription, take pear wood carbon 350g, Rhizoma Coptidis 50g, Fructus Crataegi (parched to brown) 250g, Fructus Hordei Germinatus 50g, mix homogeneously.
Embodiment 3
By crossing 20 mesh sieves after the various raw material pulverizing in prescription, take pear wood carbon 400g, Rhizoma Coptidis 100g, Fructus Crataegi (parched to brown) 300g, Fructus Hordei Germinatus 100g, mix homogeneously.
Embodiment 4
By crossing 200 mesh sieves after the various raw material pulverizing in prescription, take pear wood carbon 400g, Rhizoma Coptidis 100g, Fructus Crataegi (parched to brown) 320g, Fructus Hordei Germinatus 80g, mix homogeneously.
Embodiment 5
By crossing 200 mesh sieves after the various raw material pulverizing in prescription, take pear wood carbon 350g, Rhizoma Coptidis 80g, Fructus Crataegi (parched to brown) 250g, Fructus Hordei Germinatus 100g, mix homogeneously.
Clinical trial:
Application example 1:
Undercoat Heisui River, ermine field, Laishan District, Yantai ermine
This priority has 15 minks to suffer from this disease, their early stage, loss of appetite, listless, fervescence, asoscope is dry,, then there is dysentery, watery diarrhea in soft yellow or the Lycoperdon polymorphum Vitt of being of loose and watery stool, myasthenia of limbs, have a delicate constitution, the back of a bow of bending over, around fecal pollution is serious for anus, cut open visible gastrointestinal tract mucous the coming off of inspection, part has ulcer kitchen range.Application above-described embodiment 1 medicine is given ill mink dispensing by per kilogram of body weight 0.5g, admixes in feedstuff administration every day 1 time, is used in conjunction 5 days, with mink, stops diarrhoea, and searching for food normal is criterion of cure, and 15 minks are cured 14, and 1 invalid, and cure rate is 93%.
Application example 2:
Undercoat Heisui River, ermine field, Wendeng City, Weihai ermine
This priority has 30 minks to suffer from this disease, their early stage, and loss of appetite, listless, fervescence, asoscope is dry, and watery diarrhea, appears dysentery, in loose and watery stool soft yellow or the Lycoperdon polymorphum Vitt of being then, myasthenia of limbs, has a delicate constitution, the back of a bow of bending over, and around fecal pollution is serious for anus.Application above-described embodiment 2 medicines are given ill mink dispensing by per kilogram of body weight 0.5g, decoct soup every day and gavage administration 1 time, are used in conjunction 5 days, with mink, stop diarrhoea, and searching for food normal is criterion of cure, and 30 minks are cured 27, and 3 invalid, and cure rate is 90%.
Medicine of the present invention has no side effect, easy to use.During application, medicine of the present invention is offerd medicine to mink by per kilogram of body weight 0.5g, and administration every day 1 time, is used in conjunction 5 days, with mink, stop diarrhoea, search for food normal, be criterion of cure, clinical trial proves, totally 45 ill minks are cured 41,4 invalid, and cure rate is 91%, has unique curative effect.
Above-mentioned detailed description of the Chinese medicine composition for the treatment of mink colibacillosis being carried out with reference to embodiment; illustrative rather than determinate; can list several embodiment according to institute's limited range; therefore in the variation and the modification that do not depart under general plotting of the present invention, within should belonging to protection scope of the present invention.

Claims (4)

1. treat a Chinese medicine composition for mink colibacillosis, it is characterized in that it is to be made by following raw materials by weight portion: pear wood carbon 35-45 part, Rhizoma Coptidis 5-15 part, Fructus Crataegi (parched to brown) 25-35 part, Fructus Hordei Germinatus 5-15 part.
2. a kind of Chinese medicine composition for the treatment of mink colibacillosis according to claim 1, is characterized in that described various raw material weight umber is: 40 parts, pear wood carbon, 10 parts of Rhizoma Coptidis, 30 parts of Fructus Crataegi (parched to brown)s, 10 parts of Fructus Hordei Germinatus.
3. a kind of Chinese medicine composition for the treatment of mink colibacillosis according to claim 1, the granularity that it is characterized in that described pear wood carbon, Rhizoma Coptidis, Fructus Crataegi (parched to brown), Fructus Hordei Germinatus is 20-200 order.
4. a kind of Chinese medicine composition for the treatment of mink colibacillosis according to claim 1, is characterized in that the consumption of described Chinese medicine composition is per kilogram of body weight 0.5g.
CN201410337658.1A 2014-07-15 2014-07-15 Traditional Chinese medicine combination for treating colibacillosis of minks Pending CN104056129A (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1561864A (en) * 2004-04-14 2005-01-12 崔永南 Drink for tonifying stomach and digestion promoting drink and its preparing method
JP2010120946A (en) * 2009-12-22 2010-06-03 Maruzen Pharmaceut Co Ltd Antiinflammatory composition

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1561864A (en) * 2004-04-14 2005-01-12 崔永南 Drink for tonifying stomach and digestion promoting drink and its preparing method
JP2010120946A (en) * 2009-12-22 2010-06-03 Maruzen Pharmaceut Co Ltd Antiinflammatory composition

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
刘启明: ""家庭盖碗保健茶及药茶方"", 《开卷有益-求医问药》 *
卢玉霞等: ""禄劝县翠华乡仔猪下痢的病因及防治"", 《云南畜牧兽医》 *

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Application publication date: 20140924

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