CN105497681A - Medicine for treating infantile diarrhea caused by dampness-heat - Google Patents
Medicine for treating infantile diarrhea caused by dampness-heat Download PDFInfo
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- CN105497681A CN105497681A CN201510988500.5A CN201510988500A CN105497681A CN 105497681 A CN105497681 A CN 105497681A CN 201510988500 A CN201510988500 A CN 201510988500A CN 105497681 A CN105497681 A CN 105497681A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/02—Medicinal preparations containing materials or reaction products thereof with undetermined constitution from inanimate materials
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
- A61K33/12—Magnesium silicate
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/618—Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/34—Campanulaceae (Bellflower family)
- A61K36/344—Codonopsis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/734—Crataegus (hawthorn)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
- A61K36/8998—Hordeum (barley)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
Abstract
The invention discloses a medicine for treating infantile diarrhea caused by dampness-heat. The medicine is prepared from raw materials in parts by weight as follows: 15-20 parts of dragon's bones, 15-20 parts of oysters, 15-20 parts of gypsum, 15-20 parts of gypsum rubrum, 15-20 parts of talc, 20-25 parts of pilose asiabell roots, 15-20 parts of liquorice, 5-10 parts of hawthorn fruits, 5-10 parts of malt and 3-6 parts of tangerine peel. The medicine for treating infantile diarrhea caused by dampness-heat is prepared from ten compatible natural Chinese herbal medicines scientifically, the formula is simple, the raw materials synergistically perform the functions of clearing heat, removing dampness, astringing yin and strengthening intestines, and the medicine takes effect quickly, can treat both root and symptom causes and does not have toxic or side effects; besides, a preparation method is simple, the medicine is convenient to take and low in cost, and the effective rate of the medicine is higher than 95%.
Description
Technical field
The present invention relates to Chinese medicine, specifically a kind of medicine being used for the treatment of the infantile diarrhea caused by diarrhea due to damp-heat.
Background technology
Infantile diarrhea, be many cause of diseases, multifactor cause based on diarrhoea one group of disease.Main feature is that times of defecation increases and character changes, can with the symptoms such as heating, vomiting, stomachache and water, electrolyte, acid base imbalance in various degree.Cause of disease can be caused by virus (being mainly human rotavirus and other enterovirus), antibacterial (Escherichia coli, enterotoxigenic E．Coli, Enterohemorrhagic E.coli, enteroinvasive E．Coli and Salmonella typhimurium, campylobacter jejuni, yersinia enterocolitica, S. aureus L-forms etc.), parasite, fungus etc.Enteric flora disturbance caused by extra intestinal infection, abuse of antibiotics, allergy, improper feeding and climatic factor also can cause a disease.It is the commonly encountered diseases of 2 years old Infants Below.
Due to diarrhoea, absorption of nutrient ingredients is poor, adds appetite difference, takes in nutrient substance and also reduces, various nutrient substance can be caused to lack.Chronic diarrhea is particularly serious, common nutritious bad disease, nutritional anemia and various avitaminosis.After long-term diarrhea, systemic resistance power is low, can the various infection of secondary, common are otitis media, bronchitis, bronchopneumonia, urinary system infection, skin infection and septicemia etc.
Present is main mainly with western medicine, but effect is comparatively slow, and its side effect is large, can cause other diseases.And the therapeutic efficiency of some current Chinese medicines is also not satisfactory, and curative effect is not remarkable.
Summary of the invention
The object of this invention is to provide the medicine being used for the treatment of the infantile diarrhea caused by diarrhea due to damp-heat that a kind of good effect, short treating period, cost are low, have no side effect.
The technical scheme realizing the object of the invention is:
Be used for the treatment of a medicine for the infantile diarrhea caused by diarrhea due to damp-heat, the raw material primarily of following weight parts proportioning is made:
Os Draconis 15-20 part, Concha Ostreae 15-20 part, Gypsum Fibrosum 15-20 part, Mirabilitum crystallina 15-20 part, Talcum 15-20 part, Radix Codonopsis 20-25 part, Radix Glycyrrhizae 15-20 part, Fructus Crataegi 5-10 part, Fructus Hordei Germinatus 5-10 part, Pericarpium Citri Reticulatae 3-6 part.
The above-mentioned medicine being used for the treatment of the infantile diarrhea caused by diarrhea due to damp-heat, optimum weight part proportioning of each raw material is:
Os Draconis 18 parts, Concha Ostreae 18 parts, Gypsum Fibrosum 18 parts, Mirabilitum crystallina 18 parts, 18 parts, Talcum, Radix Codonopsis 22 parts, 18 parts, Radix Glycyrrhizae, Fructus Crataegi 8 parts, 8 parts, Fructus Hordei Germinatus, Pericarpium Citri Reticulatae 4 parts.
Described raw medicinal material is in shop of Chinese medicines and commercially available.
The preparation method of medicine of the present invention is as follows: take each crude drug by weight ratio, add mixing and be placed in container, add material quantity weight 10-20 soak by water doubly 3 times again, each decoction 35-45min, merges decoction liquor, filter and remove residue, it is the extractum of 1.20-1.30 that filtrate is concentrated into relative density at 50-60 DEG C, add adjuvant, make corresponding dosage form, to obtain final product.
In the present invention, pharmacology, effect of each crude drug are as follows:
Os Draconis: tranquillization with heavy prescription tranquillizing the mind by relieving convulsion, arresting sweating controlling nocturnal emission with astringent drugs, hemostasis astringing intestine to stop diarrhea, promoting tissue regeneration and ulcer healing.Control infantile convulsion demented, palpitation with a distress feeling is forgetful, insomnia and dreamful sleep, spontaneous sweating, and seminal emission stranguria with turbid discharge, tell nosebleed and have blood in stool, bleeding not during menses, dysentery proctoptosis, ulcer does not close up for a long time.
Concha Ostreae: have tranquillization with heavy prescription, YANG hyperactivity suppressing nourishing YIN, effect of hard masses softening and resolving; Palpitation with fear insomnia can be treated, vertigo and tinnitus, spontaneous sweating, seminal emission metrorrhagia and leukorrhagia, the diseases such as stomachache acid regurgitation.
Gypsum Fibrosum: raw with having clearing away heat-fire, effect that relieving restlessness is quenched the thirst; Be usually used in fever caused by exogenous pathogenic factors, high hot excessive thirst, dyspnea and cough due to lung-heat, the high Sheng of stomach-fire, headache, toothache.
Mirabilitum crystallina: clearing away heat-fire, sharp key, detumescence.For calentura excessive thirst, erysipelas is scalded.
Talcum: inducing diuresis for treating stranguria syndrome, clearing away summer-heat, damp eliminating sore.For pyretic stranguria, stranguria caused by urinary stone, urinates hot puckery pain, heat-damp in summer excessive thirst, damp and hot watery diarrhea.
Radix Codonopsis: have invigorating the spleen and replenishing QI, quench the thirst, spleen invigorating lung benefiting, nourishing blood to promote the production of body fluid.For deficiency of both the splenic and pulmonary QI, lack of appetite asthenia, cough dyspnea due to deficiency, insufficiency of vital energy and blood, shallow complexion, shortness of breath and palpitation, Tianjin wound is thirsty, and interior-heat is quenched one's thirst.Lazy speech is losed heart, myasthenia of limbs, be off one's feed, the deficiency of vital energy, gas Tianjin two are empty, QI and blood is two loses and the disease such as blood deficiency and yellow complexion.
Radix Glycyrrhizae: there is invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, effect of coordinating the actions of various ingredients in a prescription.Be usually used in weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
Fructus Crataegi: promoting digestion and invigorating the stomach, circulation of qi promoting dissipating blood stasis, changes turbid blood fat reducing.For meat stagnation, gastral cavilty distension, dysentery is suffered from abdominal pain, blood stasis amenorrhea, postpartum stagnation, trusted subordinate's twinge, obstruction of qi in the chest and cardialgia, hernia pain, hyperlipemia.The effect of Fructus Crataegi (parched to brown) dyspepsia and intestinal stasis relieving strengthens.For meat stagnation, dysentery is not well.
Fructus Hordei Germinatus: promote qi circulation digestion promoting, spleen benefiting and stimulating the appetite, galactopoiesis relieving distension.Do not disappear for food stagnation, abdominal distention, insufficiency of the spleen lack of appetite, milk smoulders, distending pain of the breast, and women weans, hypochondriac pain due to stagnation of liverQI, stomachache due to hyperactive liver-QI attacking the stomach.
Pericarpium Citri Reticulatae: regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm.For distension and fullness in the abdomen, lack of appetite and vomiting, cough with copious phlegm.
The present invention is used for the treatment of the medicine of the infantile diarrhea caused by diarrhea due to damp-heat, choose 10 kinds of natural Chinese medicine scientific compatibility, formula is simple, each crude drug synergism plays the effect of removing damp-heat, the solid intestinal of yin fluid astringing, instant effect, treating both the principal and secondary aspects of a disease, has no side effect, and its preparation method is simple, taking convenience, cost is low.
Detailed description of the invention
Below in conjunction with embodiment, content of the present invention is further described, but is not limitation of the invention.
Embodiment 1
Be used for the treatment of a medicine for the infantile diarrhea caused by diarrhea due to damp-heat, the raw material primarily of following weight parts proportioning is made:
Os Draconis 15kg, Concha Ostreae 15kg, Gypsum Fibrosum 15kg, Mirabilitum crystallina 15kg, Talcum 15kg, Radix Codonopsis 20kg, Radix Glycyrrhizae 15kg, Fructus Crataegi 5kg, Fructus Hordei Germinatus 5kg, Pericarpium Citri Reticulatae 3kg.
Preparation method is as follows: take the mixing of each crude drug be placed in container by above-mentioned, then add the soak by water 3 times of material quantity weight 10 times, decoct 35min at every turn, merge decoction liquor, filter and remove residue, it is the extractum of 1.20 that filtrate is concentrated into relative density at 50 DEG C, add adjuvant, make tablet, every sheet 0.1g.
Embodiment 2
Be used for the treatment of a medicine for the infantile diarrhea caused by diarrhea due to damp-heat, the raw material primarily of following weight parts proportioning is made:
Os Draconis 18kg, Concha Ostreae 18kg, Gypsum Fibrosum 18kg, Mirabilitum crystallina 18kg, Talcum 18kg, Radix Codonopsis 22kg, Radix Glycyrrhizae 18kg, Fructus Crataegi 8kg, Fructus Hordei Germinatus 8kg, Pericarpium Citri Reticulatae 4kg.
Preparation method is as follows: take the mixing of each crude drug be placed in container by above-mentioned, then add the soak by water 3 times of material quantity weight 15 times, decoct 38min at every turn, merge decoction liquor, filter and remove residue, it is the extractum of 1.20 that filtrate is concentrated into relative density at 55 DEG C, add adjuvant, make tablet, every sheet 0.2g.
Embodiment 3
Be used for the treatment of a medicine for the infantile diarrhea caused by diarrhea due to damp-heat, the raw material primarily of following weight parts proportioning is made:
Os Draconis 20kg, Concha Ostreae 20kg, Gypsum Fibrosum 20kg, Mirabilitum crystallina 20kg, Talcum 20kg, Radix Codonopsis 25kg, Radix Glycyrrhizae 20kg, Fructus Crataegi 10kg, Fructus Hordei Germinatus 10kg, Pericarpium Citri Reticulatae 6kg.
Preparation method is as follows: take the mixing of each crude drug be placed in container by above-mentioned, then add the soak by water 3 times of material quantity weight 18 times, decoct 42min at every turn, merge decoction liquor, filter and remove residue, it is the extractum of 1.30 that filtrate is concentrated into relative density at 58 DEG C, add adjuvant, make pill, every 0.4g.
Embodiment 4
Be used for the treatment of a medicine for the infantile diarrhea caused by diarrhea due to damp-heat, the raw material primarily of following weight parts proportioning is made:
Os Draconis 20kg, Concha Ostreae 20kg, Gypsum Fibrosum 20kg, Mirabilitum crystallina 20kg, Talcum 20kg, Radix Codonopsis 25kg, Radix Glycyrrhizae 20kg, Fructus Crataegi 10kg, Fructus Hordei Germinatus 10kg, Pericarpium Citri Reticulatae 6kg.
Preparation method is as follows: take the mixing of each crude drug be placed in container by above-mentioned, then add the soak by water 3 times of material quantity weight 20 times, decoct 45min at every turn, merge decoction liquor, filter and remove residue, it is the extractum of 1.30 that filtrate is concentrated into relative density at 60 DEG C, add adjuvant, make pill, every 0.5g.
In order to prove the clinical efficacy of Chinese medicine of the present invention further, selecting 100 examples of accepting for medical treatment in patient, clinical observation is carried out to the curative effect of medicine of the present invention.Age 1-4 year, be divided into 4 groups at random, often group be 25 example, be respectively experimental group 1-4 group.
Experimental group 1-4 group takes the medicine of embodiment 1-4 respectively, every day 2 times, each 3 slices/for oral administration, within 4 days, is a course for the treatment of, takes 2 courses for the treatment of continuously.Wherein effective 92 examples, effective 95 examples, cure 90 examples, invalid 5 examples, cure rate 90%, effective percentage 95%.
Claims (3)
1. be used for the treatment of a medicine for the infantile diarrhea caused by diarrhea due to damp-heat, it is characterized in that: the raw material primarily of following weight parts proportioning is made:
Os Draconis 15-20 part, Concha Ostreae 15-20 part, Gypsum Fibrosum 15-20 part, Mirabilitum crystallina 15-20 part, Talcum 15-20 part, Radix Codonopsis 20-25 part, Radix Glycyrrhizae 15-20 part, Fructus Crataegi 5-10 part, Fructus Hordei Germinatus 5-10 part, Pericarpium Citri Reticulatae 3-6 part.
2. the medicine being used for the treatment of the infantile diarrhea caused by diarrhea due to damp-heat according to claim 1, is characterized in that: optimum weight part proportioning of each raw material is:
Os Draconis 18 parts, Concha Ostreae 18 parts, Gypsum Fibrosum 18 parts, Mirabilitum crystallina 18 parts, 18 parts, Talcum, Radix Codonopsis 22 parts, 18 parts, Radix Glycyrrhizae, Fructus Crataegi 8 parts, 8 parts, Fructus Hordei Germinatus, Pericarpium Citri Reticulatae 4 parts.
3. the medicine being used for the treatment of the infantile diarrhea caused by diarrhea due to damp-heat according to claim 1, is characterized in that:
Preparation method is as follows: take each crude drug by weight ratio, add mixing and be placed in container, add material quantity weight 10-20 soak by water doubly 3 times again, each decoction 35-45min, merges decoction liquor, filter and remove residue, it is the extractum of 1.20-1.30 that filtrate is concentrated into relative density at 50-60 DEG C, add adjuvant, make corresponding dosage form, to obtain final product.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201510988500.5A CN105497681A (en) | 2015-12-25 | 2015-12-25 | Medicine for treating infantile diarrhea caused by dampness-heat |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201510988500.5A CN105497681A (en) | 2015-12-25 | 2015-12-25 | Medicine for treating infantile diarrhea caused by dampness-heat |
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| CN105497681A true CN105497681A (en) | 2016-04-20 |
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| CN201510988500.5A Pending CN105497681A (en) | 2015-12-25 | 2015-12-25 | Medicine for treating infantile diarrhea caused by dampness-heat |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113855734A (en) * | 2021-09-29 | 2021-12-31 | 山西健硕食品药品研究院有限公司 | Medicine for treating diarrhea and preparation method thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102178768A (en) * | 2011-04-12 | 2011-09-14 | 吉林农业大学 | Chinese medicine composite for treating horse damp and hot diarrhea and preparation method thereof |
-
2015
- 2015-12-25 CN CN201510988500.5A patent/CN105497681A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102178768A (en) * | 2011-04-12 | 2011-09-14 | 吉林农业大学 | Chinese medicine composite for treating horse damp and hot diarrhea and preparation method thereof |
Non-Patent Citations (2)
| Title |
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| 李志山 等: "龙牡三石汤治疗小儿重型腹泻51例", 《陕西中医》 * |
| 杨玺: "《婴幼儿保健小验方》", 31 May 2007, 北京科学技术文献出版社 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113855734A (en) * | 2021-09-29 | 2021-12-31 | 山西健硕食品药品研究院有限公司 | Medicine for treating diarrhea and preparation method thereof |
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