CN105435004A - Medicine used for treating infantile anorexia caused by yin deficiency of spleen and stomach - Google Patents

Medicine used for treating infantile anorexia caused by yin deficiency of spleen and stomach Download PDF

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CN105435004A
CN105435004A CN201510988608.4A CN201510988608A CN105435004A CN 105435004 A CN105435004 A CN 105435004A CN 201510988608 A CN201510988608 A CN 201510988608A CN 105435004 A CN105435004 A CN 105435004A
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parts
spleen
stomach
radix
medicine
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林书凤
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • A61K36/8998Hordeum (barley)
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    • A61K35/56Materials from animals other than mammals
    • A61K35/57Birds; Materials from birds, e.g. eggs, feathers, egg white, egg yolk or endothelium corneum gigeriae galli
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • AHUMAN NECESSITIES
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/34Campanulaceae (Bellflower family)
    • A61K36/342Adenophora
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/42Cucurbitaceae (Cucumber family)
    • A61K36/428Trichosanthes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/734Crataegus (hawthorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8967Lilium, e.g. tiger lily or Easter lily
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8968Ophiopogon (Lilyturf)
    • AHUMAN NECESSITIES
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8969Polygonatum (Solomon's seal)
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    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
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    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/51Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/53Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

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Abstract

The invention discloses a medicine used for treating infantile anorexia caused by yin deficiency of the spleen and stomach. The medicine is mainly prepared from the following raw materials in parts by weight: 8-12 parts of ladybell root, 8-12 parts of dwarf lilyturf tuber, 8-12 parts of hyacinth beans, 8-12 parts of fragrant solomonseal rhizome, 8-12 parts of Mongolian snakegourd root, 6-10 parts of parched hawthorn fruit, 6-10 parts of coking malt, 6-10 parts of chicken gizzard-membrane and 12-18 parts of lily. The medicine used for treating infantile anorexia caused by yin deficiency of the spleen and stomach is characterized by selecting nine natural traditional Chinese medicines to undergo scientific compatibility, is simple in formula, has the effects of nourishing stomach yin and promoting appetite through synergy of the active pharmaceutical ingredients, takes effect quickly, treats both symptoms and root causes, does not have toxic or side effect, is simple in preparation method, is convenient to take, is low in cost and has effective rate over 96.5%.

Description

Be used for the treatment of the medicine of the infantile anorexia caused by deficiency of YIN of the spleen and stomach
Technical field
The present invention relates to Chinese medicine, specifically a kind of medicine being used for the treatment of the infantile anorexia caused by deficiency of YIN of the spleen and stomach.
Background technology
Infantile anorexia refers to that children's (mainly 3 ~ 6 years old) longer-term loss of appetite or anorexia are main symptom.It is a kind of symptom, not one independently disease.Infantile anorexia is also known as digestive functional disturbance.Infantile anorexia is very common for period children's, and main symptom has vomiting, inappetence, diarrhoea, constipation, and abdominal distention is suffered from abdominal pain and had blood in stool.Normal children is emptying every 3 ~ 4h gastric content, blood glucose decline, will appetite be produced, improper feeding or dietary habit bad, as variable interval of having a meal, eat a piece ante cibum or confection, gastric always has thing, and blood glucose does not decline, and would not have appetite.
Primary disease can not get alleviating for a long time, can complication infantile malnutrition, even cause dysplasia etc., children's is in continuous growth promoter, the adult that compares needs more various allowance of nutrients, if various allowance of nutrients is not enough, the normal growth that not only can affect children's is grown, growth promoter is made to stagnate time serious, internal organs of the body atrophy, the normal immune system of children's will inevitably be affected like this, as due to anorexia caused serious protein--heat energy is not enough malnutrition infant, can occur that Cellular Immune Disturbances and serum antibody reduce, thus easily there is various antibacterial, the infection such as virus and fungus, and infection often continues, protracted course of disease, even threat to life, show as repeated cold, fever, or recurrent cough, do not eat, not active, body weight does not increase, size is not long.
Present is main mainly with western medicine, but effect is comparatively slow, and its side effect is large, can cause other diseases.And the therapeutic efficiency of some current Chinese medicines is also not satisfactory, and curative effect is not remarkable.
Summary of the invention
The object of this invention is to provide the medicine being used for the treatment of the infantile anorexia caused by deficiency of YIN of the spleen and stomach that a kind of good effect, short treating period, cost are low, have no side effect.
The technical scheme realizing the object of the invention is:
Be used for the treatment of a medicine for the infantile anorexia caused by deficiency of YIN of the spleen and stomach, the raw material primarily of following weight parts proportioning is made:
Radix Adenophorae (Radix Glehniae) 8-12 part, Radix Ophiopogonis 8-12 part, Seem Lablab Album 8-12 part, Rhizoma Polygonati Odorati 8-12 part, Radix Trichosanthis 8-12 part, Fructus Crataegi (parched to brown) 6-10 part, Fructus Hordei Germinatus (parched to brown) 6-10 part, Endothelium Corneum Gigeriae Galli 6-10 part, Bulbus Lilii 12-18 part.
The above-mentioned medicine being used for the treatment of the infantile anorexia caused by deficiency of YIN of the spleen and stomach, optimum weight part proportioning of each raw material is:
Radix Adenophorae (Radix Glehniae) 10 parts, Radix Ophiopogonis 10 parts, 10 parts, Seem Lablab Album, Rhizoma Polygonati Odorati 10 parts, Radix Trichosanthis 10 parts, Fructus Crataegi (parched to brown) 8 parts, Fructus Hordei Germinatus (parched to brown) 8 parts, Endothelium Corneum Gigeriae Galli 8 parts, Bulbus Lilii 15 parts.
Described raw medicinal material is in shop of Chinese medicines and commercially available.
The preparation method of medicine of the present invention is as follows: take each crude drug by weight ratio, add mixing and be placed in container, add material quantity weight 10-20 soak by water doubly 3 times again, each decoction 25-35min, merges decoction liquor, filter and remove residue, it is the extractum of 1.10-1.30 that filtrate is concentrated into relative density at 50-60 DEG C, add adjuvant, make corresponding dosage form, to obtain final product.
In the present invention, pharmacology, effect of each crude drug are as follows:
Radix Adenophorae (Radix Glehniae): be used as medicine with root.Radix Glehniae sweet in the mouth is sweet, is clinical conventional drugs for nourishing yin, nourishing YIN and clearing away lung-heat, expelling phlegm for arresting cough.Cure mainly dryness of the lung dry cough, consumption of body fluid caused by febrile disease, the disease such as thirsty.Main product in Shandong, Hebei, Liaoning, the ground such as Inner Mongol.Another name glehniae,radix, glehniae,radix, silver-colored Radix Adenophorae (Radix Glehniae), RADIX GLEHNIAE from Liaoning of China, Soviet Union's Radix Glehniae, Radix Glehniae, RADIX GLEHNIAE.
Radix Ophiopogonis: sweet in the mouth, micro-hardship, cold nature, returns stomach, lung, heart channel, has nourishing YIN and moistening the lung, reinforcing stomach reg fluid, the effect of the relieving restlessness that clears away heart-fire, for dryness of the lung dry cough, the disease such as deficiency of YIN consumptive disease is coughed, sore throat pharyngalgia, Tianjin wound are thirsty, interior-heat is quenched one's thirst, vexed insomnia, dryness of the intestine constipation.
Seem Lablab Album: can spleen invigorating dehumidifying.Have wet for insufficiency of the spleen, fatigue and asthenia, eats loose stool less, or edema; Women's lukorrhagia due to hypofunction of the spleen; Heat-damp in summer is trouble, incoordination between the spleen and stomach, vomiting and diarrhoea.
Rhizoma Polygonati Odorati: nourishing YIN to relieve dryness, promoting the production of body fluid to quench thirst.For lung stomach-Yin wound, cough caused by dryness-heat, dry throat and mouth, interior-heat is quenched one's thirst.
Radix Trichosanthis: be the root of cucurbitaceous plant Chinese juniper beach wormwood is a kind of Chinese medicine, and be clearing away heat-fire class medicine, its concrete effect is clearing away heat-fire, promoting the production of body fluid to quench thirst, and evacuation of pus is subsided a swelling.Cure mainly: control calentura thirsty, quench one's thirst, jaundice, dryness of the lung hemoptysis, carbuncle, hemorrhoid flaccidity.For treatment diabetes, conventional it and drugs for nourishing yin with the use of, to reach the effect for the treatment of both the principal and secondary aspects of a disease.
Fructus Crataegi (parched to brown): the function having promoting digestion and invigorating the stomach, blood circulation promoting and blood stasis dispelling, convergence dysentery relieving.To meat amass phlegm retention, feeling of fullness acid regurgitation, dysentery hemorrhoidal hamorrhage, lumbago hernia, puerperal after-pains, lochiorrhea, children's breast food stagnate etc., all effective in cure.
Fructus Hordei Germinatus (parched to brown): for insufficiency of the spleen lack of appetite, dyspepsia, breast distension, milk smoulders.
Endothelium Corneum Gigeriae Galli: removing food stagnancy is stagnant, strengthening the spleen and stomach.Control food stagnation distension, vomiting regurgitation, dysentery, infantile malnutrition, quenches one's thirst, incontinence of urine, sore throat tonsillitis, ulcerative gingivitis aphtha.
The present invention is used for the treatment of the medicine of the infantile anorexia caused by deficiency of YIN of the spleen and stomach, choose 9 kinds of natural Chinese medicine scientific compatibility, formula is simple, each crude drug synergism plays nourishing stomach-Yin, orectic effect, instant effect, treating both the principal and secondary aspects of a disease, has no side effect, and its preparation method is simple, taking convenience, cost is low.
Detailed description of the invention
Below in conjunction with embodiment, content of the present invention is further described, but is not limitation of the invention.
Embodiment 1
Be used for the treatment of a medicine for the infantile anorexia caused by deficiency of YIN of the spleen and stomach, the raw material primarily of following weight parts proportioning is made:
Radix Adenophorae (Radix Glehniae) 8kg, Radix Ophiopogonis 8kg, Seem Lablab Album 8kg, Rhizoma Polygonati Odorati 8kg, Radix Trichosanthis 8kg, Fructus Crataegi (parched to brown) 6kg, Fructus Hordei Germinatus (parched to brown) 6kg, Endothelium Corneum Gigeriae Galli 6kg, Bulbus Lilii 12kg.
Preparation method is as follows: take the mixing of each crude drug be placed in container by above-mentioned, then add the soak by water 3 times of material quantity weight 10 times, decoct 25min at every turn, merge decoction liquor, filter and remove residue, it is the extractum of 1.10 that filtrate is concentrated into relative density at 50 DEG C, add adjuvant, make tablet, every sheet 0.1g.
Embodiment 2
Be used for the treatment of a medicine for the infantile anorexia caused by deficiency of YIN of the spleen and stomach, the raw material primarily of following weight parts proportioning is made:
Radix Adenophorae (Radix Glehniae) 10kg, Radix Ophiopogonis 10kg, Seem Lablab Album 10kg, Rhizoma Polygonati Odorati 10kg, Radix Trichosanthis 10kg, Fructus Crataegi (parched to brown) 8kg, Fructus Hordei Germinatus (parched to brown) 8kg, Endothelium Corneum Gigeriae Galli 8kg, Bulbus Lilii 15kg.
Preparation method is as follows: take the mixing of each crude drug be placed in container by above-mentioned, then add the soak by water 3 times of material quantity weight 15 times, decoct 28min at every turn, merge decoction liquor, filter and remove residue, it is the extractum of 1.20 that filtrate is concentrated into relative density at 54 DEG C, add adjuvant, make tablet, every sheet 0.2g.
Embodiment 3
Be used for the treatment of a medicine for the infantile anorexia caused by deficiency of YIN of the spleen and stomach, the raw material primarily of following weight parts proportioning is made:
Radix Adenophorae (Radix Glehniae) 12kg, Radix Ophiopogonis 12kg, Seem Lablab Album 12kg, Rhizoma Polygonati Odorati 12kg, Radix Trichosanthis 12kg, Fructus Crataegi (parched to brown) 10kg, Fructus Hordei Germinatus (parched to brown) 10kg, Endothelium Corneum Gigeriae Galli 10kg, Bulbus Lilii 18kg.
Preparation method is as follows: take the mixing of each crude drug be placed in container by above-mentioned, then add the soak by water 3 times of material quantity weight 18 times, decoct 32min at every turn, merge decoction liquor, filter and remove residue, it is the extractum of 1.30 that filtrate is concentrated into relative density at 56 DEG C, add adjuvant, make pill, every 0.4g.
Embodiment 4
Be used for the treatment of a medicine for the infantile anorexia caused by deficiency of YIN of the spleen and stomach, the raw material primarily of following weight parts proportioning is made:
Radix Adenophorae (Radix Glehniae) 12kg, Radix Ophiopogonis 12kg, Seem Lablab Album 12kg, Rhizoma Polygonati Odorati 12kg, Radix Trichosanthis 12kg, Fructus Crataegi (parched to brown) 10kg, Fructus Hordei Germinatus (parched to brown) 10kg, Endothelium Corneum Gigeriae Galli 10kg, Bulbus Lilii 18kg.
Preparation method is as follows: take the mixing of each crude drug be placed in container by above-mentioned, then add the soak by water 3 times of material quantity weight 20 times, decoct 35min at every turn, merge decoction liquor, filter and remove residue, it is the extractum of 1.30 that filtrate is concentrated into relative density at 60 DEG C, add adjuvant, make pill, every 0.5g.
In order to prove the clinical efficacy of Chinese medicine of the present invention further, selecting 200 examples of accepting for medical treatment in patient, clinical observation is carried out to the curative effect of medicine of the present invention.Age 2-6 year, be divided into 4 groups at random, often group be 50 example, be respectively experimental group 1-4 group.
Experimental group 1-4 group takes the medicine of embodiment 1-4 respectively, every day 2 times, each 3 slices/for oral administration, within 5 days, is a course for the treatment of, takes 2 courses for the treatment of continuously.Wherein effective 190 examples, effective 193 examples, cure 188 examples, invalid 7 examples, cure rate 94%, effective percentage 96.5%.

Claims (3)

1. be used for the treatment of a medicine for the infantile anorexia caused by deficiency of YIN of the spleen and stomach, it is characterized in that: the raw material primarily of following weight parts proportioning is made:
Radix Adenophorae (Radix Glehniae) 8-12 part, Radix Ophiopogonis 8-12 part, Seem Lablab Album 8-12 part, Rhizoma Polygonati Odorati 8-12 part, Radix Trichosanthis 8-12 part, Fructus Crataegi (parched to brown) 6-10 part, Fructus Hordei Germinatus (parched to brown) 6-10 part, Endothelium Corneum Gigeriae Galli 6-10 part, Bulbus Lilii 12-18 part.
2. the medicine being used for the treatment of the infantile anorexia caused by deficiency of YIN of the spleen and stomach according to claim 1, is characterized in that: optimum weight part proportioning of each raw material is:
Radix Adenophorae (Radix Glehniae) 10 parts, Radix Ophiopogonis 10 parts, 10 parts, Seem Lablab Album, Rhizoma Polygonati Odorati 10 parts, Radix Trichosanthis 10 parts, Fructus Crataegi (parched to brown) 8 parts, Fructus Hordei Germinatus (parched to brown) 8 parts, Endothelium Corneum Gigeriae Galli 8 parts, Bulbus Lilii 15 parts.
3. the medicine being used for the treatment of the infantile anorexia caused by deficiency of YIN of the spleen and stomach according to claim 1, is characterized in that:
Preparation method is as follows: take each crude drug by weight ratio, add mixing and be placed in container, add material quantity weight 10-20 soak by water doubly 3 times again, each decoction 25-35min, merges decoction liquor, filter and remove residue, it is the extractum of 1.10-1.30 that filtrate is concentrated into relative density at 50-60 DEG C, add adjuvant, make corresponding dosage form, to obtain final product.
CN201510988608.4A 2015-12-25 2015-12-25 Medicine used for treating infantile anorexia caused by yin deficiency of spleen and stomach Pending CN105435004A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106177649A (en) * 2016-08-22 2016-12-07 黄琴 For treating the medicine of infantile anorexia
CN110140908A (en) * 2019-05-28 2019-08-20 广西中医药大学 A kind of taste conditioning herbal cuisine

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103599355A (en) * 2013-11-28 2014-02-26 佘坤 Traditional Chinese medicine for treating anorexia

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103599355A (en) * 2013-11-28 2014-02-26 佘坤 Traditional Chinese medicine for treating anorexia

Non-Patent Citations (2)

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Title
吴杰妍: "中西医结合治疗小儿厌食症疗效观察", 《吉林中医药》 *
杨景海 等: "《古今中医效验秘方宝典》", 31 January 2009, 北京燕山出版社 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106177649A (en) * 2016-08-22 2016-12-07 黄琴 For treating the medicine of infantile anorexia
CN110140908A (en) * 2019-05-28 2019-08-20 广西中医药大学 A kind of taste conditioning herbal cuisine

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