CN104055009A - Black fungus pinenut composite immunity-improving granule and preparation method thereof - Google Patents
Black fungus pinenut composite immunity-improving granule and preparation method thereof Download PDFInfo
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- CN104055009A CN104055009A CN201310086094.4A CN201310086094A CN104055009A CN 104055009 A CN104055009 A CN 104055009A CN 201310086094 A CN201310086094 A CN 201310086094A CN 104055009 A CN104055009 A CN 104055009A
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- 241000233866 Fungi Species 0.000 title claims abstract description 28
- 238000002360 preparation method Methods 0.000 title claims abstract description 11
- 239000008187 granular material Substances 0.000 title claims abstract 6
- 239000002131 composite material Substances 0.000 title abstract 5
- 239000000843 powder Substances 0.000 claims abstract description 33
- 230000036039 immunity Effects 0.000 claims abstract description 29
- 150000004676 glycans Chemical class 0.000 claims abstract description 16
- 229920001282 polysaccharide Polymers 0.000 claims abstract description 16
- 239000005017 polysaccharide Substances 0.000 claims abstract description 16
- 108090000623 proteins and genes Proteins 0.000 claims abstract description 9
- 102000004169 proteins and genes Human genes 0.000 claims abstract description 9
- 238000005469 granulation Methods 0.000 claims abstract description 3
- 230000003179 granulation Effects 0.000 claims abstract description 3
- 235000011615 Pinus koraiensis Nutrition 0.000 claims description 16
- 240000007263 Pinus koraiensis Species 0.000 claims description 16
- 244000241838 Lycium barbarum Species 0.000 claims description 13
- 235000015459 Lycium barbarum Nutrition 0.000 claims description 13
- 150000001875 compounds Chemical class 0.000 claims description 12
- 239000002245 particle Substances 0.000 claims description 11
- 235000013399 edible fruits Nutrition 0.000 claims description 9
- 241000221377 Auricularia Species 0.000 claims description 8
- 239000000284 extract Substances 0.000 claims description 8
- 235000015468 Lycium chinense Nutrition 0.000 claims description 7
- 238000005238 degreasing Methods 0.000 claims description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 6
- 235000021552 granulated sugar Nutrition 0.000 claims description 5
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 claims description 4
- 229930003944 flavone Natural products 0.000 claims description 4
- 150000002213 flavones Chemical class 0.000 claims description 4
- 235000011949 flavones Nutrition 0.000 claims description 4
- 238000002386 leaching Methods 0.000 claims description 4
- 239000013049 sediment Substances 0.000 claims description 4
- 238000003756 stirring Methods 0.000 claims description 4
- 239000006228 supernatant Substances 0.000 claims description 4
- 239000012141 concentrate Substances 0.000 claims description 3
- 235000005979 Citrus limon Nutrition 0.000 claims description 2
- 244000131522 Citrus pyriformis Species 0.000 claims description 2
- 244000170916 Paeonia officinalis Species 0.000 claims description 2
- 235000006484 Paeonia officinalis Nutrition 0.000 claims description 2
- 239000002253 acid Substances 0.000 claims description 2
- 239000000706 filtrate Substances 0.000 claims description 2
- 239000010665 pine oil Substances 0.000 claims description 2
- 238000001556 precipitation Methods 0.000 claims description 2
- 238000002791 soaking Methods 0.000 claims description 2
- 238000000967 suction filtration Methods 0.000 claims description 2
- 238000009777 vacuum freeze-drying Methods 0.000 claims description 2
- 230000000694 effects Effects 0.000 abstract description 14
- 239000002994 raw material Substances 0.000 abstract description 6
- 230000008901 benefit Effects 0.000 abstract description 5
- 230000036541 health Effects 0.000 abstract description 5
- 238000004519 manufacturing process Methods 0.000 abstract description 3
- 235000013305 food Nutrition 0.000 abstract description 2
- 230000002195 synergetic effect Effects 0.000 abstract description 2
- 231100000331 toxic Toxicity 0.000 abstract description 2
- 230000002588 toxic effect Effects 0.000 abstract description 2
- 240000002624 Mespilus germanica Species 0.000 abstract 4
- 235000017784 Mespilus germanica Nutrition 0.000 abstract 4
- 235000000560 Mimusops elengi Nutrition 0.000 abstract 4
- 235000007837 Vangueria infausta Nutrition 0.000 abstract 4
- 230000001900 immune effect Effects 0.000 abstract 2
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 abstract 1
- 229930006000 Sucrose Natural products 0.000 abstract 1
- 239000000047 product Substances 0.000 description 6
- 206010028980 Neoplasm Diseases 0.000 description 3
- 201000010099 disease Diseases 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- 230000036737 immune function Effects 0.000 description 3
- 210000000987 immune system Anatomy 0.000 description 3
- 230000009471 action Effects 0.000 description 2
- 201000011510 cancer Diseases 0.000 description 2
- 210000004027 cell Anatomy 0.000 description 2
- 238000002512 chemotherapy Methods 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 239000002955 immunomodulating agent Substances 0.000 description 2
- 230000002584 immunomodulator Effects 0.000 description 2
- 229940121354 immunomodulator Drugs 0.000 description 2
- 208000033065 inborn errors of immunity Diseases 0.000 description 2
- 231100000957 no side effect Toxicity 0.000 description 2
- 208000028529 primary immunodeficiency disease Diseases 0.000 description 2
- 206010003694 Atrophy Diseases 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 208000005623 Carcinogenesis Diseases 0.000 description 1
- 208000035473 Communicable disease Diseases 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- 230000003712 anti-aging effect Effects 0.000 description 1
- 230000000118 anti-neoplastic effect Effects 0.000 description 1
- 230000000259 anti-tumor effect Effects 0.000 description 1
- 230000010100 anticoagulation Effects 0.000 description 1
- 230000000386 athletic effect Effects 0.000 description 1
- 230000037444 atrophy Effects 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 230000036952 cancer formation Effects 0.000 description 1
- 231100000504 carcinogenesis Toxicity 0.000 description 1
- 230000007969 cellular immunity Effects 0.000 description 1
- 102000003675 cytokine receptors Human genes 0.000 description 1
- 108010057085 cytokine receptors Proteins 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 235000018927 edible plant Nutrition 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 230000014509 gene expression Effects 0.000 description 1
- 230000013632 homeostatic process Effects 0.000 description 1
- 230000004727 humoral immunity Effects 0.000 description 1
- 230000002218 hypoglycaemic effect Effects 0.000 description 1
- 230000000091 immunopotentiator Effects 0.000 description 1
- 230000007365 immunoregulation Effects 0.000 description 1
- 230000001771 impaired effect Effects 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 230000001788 irregular Effects 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
- 210000002540 macrophage Anatomy 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 230000000242 pagocytic effect Effects 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 230000035479 physiological effects, processes and functions Effects 0.000 description 1
- 230000035790 physiological processes and functions Effects 0.000 description 1
- 230000002980 postoperative effect Effects 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 238000001959 radiotherapy Methods 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000004083 survival effect Effects 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 210000001541 thymus gland Anatomy 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Abstract
The invention belongs to the field of health care food, and relates to an immunity-improving product and a preparation method thereof. The invention solves the problems of side effect, non-ideal effect, and tedious production process for common immunologic products. The black fungus pinenut composite immunity-improving granule selects northeast black fungus, red pinenuts, and Ningxia medlar as main raw materials, and the mass percents of the raw materials are 10%-20% of black fungus polysaccharide powder, 10%-20% of red pinenut degreased protein powder, 5%-10% of medlar powder, and 50%-70% of white sugar. The preparation method comprises: extracting black fungus and pinenut to obtain black fungus polysaccharide powder and pinenut protein powder, mixing with medlar powder, and performing granulation to obtain the black fungus pinenut composite immunity-improving granule. According to the black fungus pinenut composite immunity-improving granule, immunologic synergistic effect is generated by scientific combination of components of black fungus polysaccharide, medlar polysaccharide and pinenut protein which have immunity-improving effect, and thus the effect of high-efficient and rapid immunity improvement is reached; the black fungus pinenut composite immunity-improving granule has the advantages of wide sources, no toxic or side effects, high safety, wide immunity-improving effect, and the like.
Description
Affiliated technical field
The present invention relates to a kind of raising immunity product and preparation method thereof.
Background technology
Immune system mainly plays a part physiology defence, homeostasis and immunosurveillance in human body, is that human body is resisted pathogen and invaded most important safeguard system.Once immunologic function is low, just very easily cause the infection of bacterium, virus, fungi, the most directly performance is exactly liable to illness.Studies confirm that, society hypoimmunity mainly concentrates on three class crowds: the one, and disease crowd, tumor and cancer patient particularly, radiotherapy, chemotherapy, heavy dose of antibiotic that uses, cause cellular immunity and humoral immunity impaired, therefore improve body physique and immunologic function, alleviate chemotherapy toxic side effect, heighten the effect of a treatment, extend shorter survival and improve life quality very important for tumor patient.The 2nd, irregular, the feeding desorder of living, do not get enough athletic exercise, psychology and the large crowd of stress, various factors brings out immune system can not normally bring into play protective effect.The 3rd, infant and the elderly, infant's immune system is grown not yet ripe, because the IgG antibody obtaining from parent disappears, so easily infect, the elderly is due to atrophy of thymus gland,, also easily there is infectious diseases and malignant tumour in the decreased number of immunocyte, miopragia and cause specificity and nospecific immunity all to decline to some extent.
The shared ratio of crowd that shows according to investigations hypoimmunity raises just year by year, and the product that improves in the market immunity is multifarious, as immunomodulator, improve the health products of immunity etc., but all has certain problem.Immunomodulator has side effect to human body, and takes for a long time body and can adopt the resistance to the action of a drug; The health products that improve immunity through State Food and Drug Administration granted just have a kind more than 1,000, although of a great variety, take effect slowly, the problem ubiquity of DeGrain and side effect.
A large amount of pharmacology and clinical researches show, natural polysaccharide has raising immunity of organisms, antitumor, reducing blood lipid, hypoglycemic, anticoagulation, the anti-ageing physiological function of waiting for a long time, the polysaccharide component containing in black fungus, matrimony vine, pinenut, can induce multiple the have cell factor of immunoregulation effect and the gene expression of cytokine receptor, activate panimmunity competent cell, strengthen host immune function, can reach antineoplastic effect.In pinenut, albumen can significantly improve body's immunity, and the vigor of activating macrophage strengthens phagocytic activity, improves the ability of body resist the disease.Therefore black fungus, Korean pine benevolence, matrimony vine become the optimum feed stock that exploitation improves immunity function food.
Summary of the invention
The object of this invention is to provide a kind of function factor compound instant particles that improves immunity and preparation method thereof, there are wide material sources, have no side effect, without carcinogenesis, safe, the advantage such as immune enhancing function is extensive, adopts the combination of pure natural plant function effective components, bring into play its synergistic function, thereby reach the effect that improves immunity.
Technical scheme of the present invention is: it is primary raw material that a kind of raising immunity electuary is selected northeast black fungus, Korean pine benevolence, lycium barbarum, by effective function factor, extract and rational proportioning, make these functional components produce synergy, thereby can effectively improve immunity of organisms.Raw material mass mixture ratio is: Blackfungus polyhexose powder 10%～20%, Korean pine benevolence defatted protein powder 10%～20%, wolfberry fruit powder 5%～10%, white granulated sugar 50%～70%.The compound raising immunity of every 100g black fungus pinenut particle functional component content is: 12.72g Auricularia polysaccharide, 10.39g pinenut albumen, 6.15g LBP-X, 1.71g Polysaccharide From Korean Pine Seed, 40.22mg carrotene, 24.15mg flavones.
This technical scheme has following advantage:
(1) take black fungus, Korean pine benevolence, three kinds of medicinal and edible plants of matrimony vine is raw material, extracts and wherein effectively improves the functional component of immunity, and these functional components are carried out to science compatibility, makes it produce synergy, greatly improves action effect.
(2) application range of products is wide, is applicable to disease crowd, erratic crowd, infant and the elderly live.The patient that particularly suitable Postoperative Immunity power is low, can help it to improve immunity fast, builds up health.
(4) compare with the immunopotentiator of chemical synthesis and have advantages of that safety has no side effect; Compare with the health products of similar raising immunity that to have using dosage little, the advantage of successful.
(3) production technique of the present invention is simple, good in economic efficiency, is easy to promote.
The specific embodiment
A kind of raising immunity electuary raw material proportioning is: Blackfungus polyhexose powder 10%～20%, Korean pine benevolence defatted protein powder 10%～20%, wolfberry fruit powder 5%～10%, white granulated sugar 50%～70%.Preparation method comprises the following steps:
(1) prepare Blackfungus polyhexose powder: first black fungus is soaked in water, clean, remove the base of a fruit, then by its oven dry, pulverize, cross 60 mesh sieves, 1: 45～1: 55 stirring and leaching 2.5～3.5h of 80 ℃ of material-water ratios, uses centrifuge at the centrifugal 3～7min of 3000～4000r/min, by supernatant at Rotary Evaporators reduced pressure concentration under 60 ℃ of conditions, concentrate is dry in 80 ℃ of baking ovens, dry Auricularia extract was pulverized to 100～140 mesh sieves, obtain Auricularia polysaccharide powder.
(2) prepare degreasing pinenut albumen powder: first Korean pine benevolence is pulverized, add the benzinum cold soaking of two volumes to extract Korean pine oil three times, reclaim benzinum, the pinenut of degreasing is dried in the baking oven of 40 ℃, conducting powder is broken, cross 60 mesh sieves, 1: 25～1: 35 stirring and leaching 1.5～2.5h of 40 ℃ of material-water ratios, extracts three times.Then use centrifuge at the centrifugal 3～7min of 3000～4000r/min extract, and supernatant is carried out to suction filtration, filtrate is merged, with lemon acid for adjusting pH to 4.6, make pinenut albumen precipitation, use centrifuge at the centrifugal 3～7min of 3000～4000r/min sediment, get lower sediment freeze dryer vacuum freeze-drying, obtain degreasing pinenut albumen powder.
(3) prepare wolfberry fruit powder: matrimony vine is cleaned, put into 120 degree baking ovens, dry to expanding, becoming fragile, be peony, then pulverize, cross 120 mesh sieves.
(4) by 10%～20% Blackfungus polyhexose powder, 10%～20% Korean pine benevolence defatted protein powder, 5%～10% wolfberry fruit powder, 50%～70% white granulated sugar mixes, and with granulator granulation, obtains the compound raising immunity of black fungus pinenut particle.The compound raising immunity of every 100g black fungus pinenut particle functional component content: 12.72g Auricularia polysaccharide, 10.39g pinenut albumen, 6.15g LBP-X, 1.71g Polysaccharide From Korean Pine Seed, 40.22mg carrotene, 24.15mg flavones.
Claims (6)
1. the compound raising immunity of black fungus pinenut particle, it is characterized in that the compound raising immunity of black fungus pinenut particle is by mass percentage by Blackfungus polyhexose powder 10%～20%, Korean pine benevolence defatted protein powder 10%～20%, wolfberry fruit powder 5%～10%, white granulated sugar 50%～70% is made.
2. Blackfungus polyhexose powder, preparation method thereof according to claim 1 is as follows: first black fungus is soaked in water, clean, remove the base of a fruit, then by its oven dry, pulverize, cross 60 mesh sieves, 1: 45～1: 55 stirring and leaching 2.5～3.5h of 80 ℃ of material-water ratios, uses centrifuge at the centrifugal 3～7min of 3000～4000r/min, by supernatant at Rotary Evaporators reduced pressure concentration under 60 ℃ of conditions, concentrate is dry in 80 ℃ of baking ovens, dry Auricularia extract was pulverized to 100～140 mesh sieves, obtain Auricularia polysaccharide powder.
3. degreasing pinenut protein powder preparation method according to claim 1 is as follows: first Korean pine benevolence is pulverized, add the benzinum cold soaking of two volumes to extract Korean pine oil three times, reclaim benzinum, the pinenut of degreasing is dried in the baking oven of 40 ℃, conducting powder is broken, cross 60 mesh sieves, 1: 25～1: 35 stirring and leaching 1.5～2.5h of 40 ℃ of material-water ratios, extracts three times.Then use centrifuge at the centrifugal 3～7min of 3000～4000r/min extract, and supernatant is carried out to suction filtration, filtrate is merged, with lemon acid for adjusting pH to 4.6, make pinenut albumen precipitation, use centrifuge at the centrifugal 3～7min of 3000～4000r/min sediment, get lower sediment freeze dryer vacuum freeze-drying, obtain degreasing pinenut albumen powder.
4. preparation wolfberry fruit powder according to claim 1: matrimony vine is cleaned, put into 120 degree baking ovens, dry to expanding, becoming fragile, be peony, then pulverize, cross 120 mesh sieves.
5. the compound raising immunity of black fungus pinenut according to claim 1 preparation method of granules is as follows: by 10%～20% Blackfungus polyhexose powder; 10%～20% Korean pine benevolence defatted protein powder; 5%～10% wolfberry fruit powder; 50%～70% white granulated sugar mixes; with granulator granulation, obtain the compound raising immunity of black fungus pinenut particle.The compound raising immunity of every 100g black fungus pinenut particle functional component content: 12.72g Auricularia polysaccharide, 10.39g pinenut albumen, 6.15g LBP-X, 1.71g Polysaccharide From Korean Pine Seed, 40.22mg carrotene, 24.15mg flavones.
6. the compound raising immunity of black fungus pinenut according to claim 1 particle, it is characterized in that the compound raising immunity of every 100g black fungus pinenut particle functional component content: 12.72g Auricularia polysaccharide, 10.39g pinenut albumen, 6.15g LBP-X, 1.71g Polysaccharide From Korean Pine Seed, 40.22mg carrotene, 24.15mg flavones.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310086094.4A CN104055009A (en) | 2013-03-19 | 2013-03-19 | Black fungus pinenut composite immunity-improving granule and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201310086094.4A CN104055009A (en) | 2013-03-19 | 2013-03-19 | Black fungus pinenut composite immunity-improving granule and preparation method thereof |
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| CN104055009A true CN104055009A (en) | 2014-09-24 |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107048377A (en) * | 2017-06-20 | 2017-08-18 | 哈尔滨工业大学 | Spacefarer flies antifatigue chewable tablets and preparation method thereof for a long time |
| CN109770029A (en) * | 2017-11-13 | 2019-05-21 | 吉林农业大学 | It is a kind of using fungi polysaccharide as the sugar of functional components |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101219149A (en) * | 2007-12-28 | 2008-07-16 | 广东省微生物研究所 | Auricularia polytricha polyoses grain medicinal granules and method for preparing the same |
| CN101514226A (en) * | 2009-03-09 | 2009-08-26 | 王振宇 | Method for extracting pine nut protein of Korean pine |
-
2013
- 2013-03-19 CN CN201310086094.4A patent/CN104055009A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101219149A (en) * | 2007-12-28 | 2008-07-16 | 广东省微生物研究所 | Auricularia polytricha polyoses grain medicinal granules and method for preparing the same |
| CN101514226A (en) * | 2009-03-09 | 2009-08-26 | 王振宇 | Method for extracting pine nut protein of Korean pine |
Non-Patent Citations (1)
| Title |
|---|
| 徐秀忠等: "黑木耳多糖提取及多糖冲剂制备工艺研究", 《食品科技》, vol. 37, no. 1, 31 January 2012 (2012-01-31), pages 186 - 190 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107048377A (en) * | 2017-06-20 | 2017-08-18 | 哈尔滨工业大学 | Spacefarer flies antifatigue chewable tablets and preparation method thereof for a long time |
| CN109770029A (en) * | 2017-11-13 | 2019-05-21 | 吉林农业大学 | It is a kind of using fungi polysaccharide as the sugar of functional components |
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Application publication date: 20140924 |