CN104043020A - Traditional Chinese medicine preparation for relieving swelling and pain of third-stage internal hemorrhoids and preparation method thereof - Google Patents
Traditional Chinese medicine preparation for relieving swelling and pain of third-stage internal hemorrhoids and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine preparation for relieving the swelling and pain of third-stage internal hemorrhoids. The traditional Chinese medicine preparation is prepared from the following main raw materials in parts by weight: 15-35 parts of radix rehmanniae, 3-9 parts of rhizoma coptidis, 3-6 parts of rhizoma cimicifugae dahuricae, 6-15 parts of fried semen pruni, 6-12 parts of fructus sophorae, 6-15 parts of herba schizonepetae, 8-12 parts of radix cynanchi paniculati, 30-50 parts of carbonized sanguisorba root, 5-15 parts of pericarpium papaveris fried with vinegar, 9-16 parts of fructus psoraleae, 5-12 parts of fructus amomi, 3-9 parts of Hangzhou paeonia albiflora and 18-30 parts of portulaca oleracea. The traditional Chinese medicine preparation disclosed by the invention is scientific in formula, safe and effective, has the effects of relieving the swelling and pain, promoting blood circulation, stopping bleeding and softening hemorrhoids kernel, is quick in effect, and ensures that third-stage internal hemorrhoids do not relapse after being cured.
Description
Technical field
The present invention relates to Chinese medicine field, particularly relate to a kind of stageⅢhemorrhoid reducing swelling and alleviating pain Chinese medicinal formulae and preparation method.
background technology
Hemorrhoid are a kind of commonly encountered diseases that are positioned at anus position.Hemorrhoid can be divided into internal hemorrhoid, external hemorrhoid and mixed hemorrhoid.Blood stasis is positioned at be called " internal hemorrhoid " of anus the inside mucosa, is called " external hemorrhoid " near being positioned at anal orifice inner side, and the two has is called " mixed hemorrhoid ".Hemorrhoid the lighter made troubles to people's orthobiosis, and severe one has a strong impact on people's health.
Internal hemorrhoid is more common a kind of in hemorrhoid, also larger to the harm of human body.According to the difference of the pathological change of internal hemorrhoid and development degree, often internal hemorrhoid is divided into clinically to three phases.First phase internal hemorrhoid symptom is lighter, and under sight glass, visible mucosa is the nodositas differing in size, and matter is soft, and color is red; While referring to inspection, the softness of pressing, mucous membrane surface is very thin, is easily frayed and hemorrhage during stool, and stool is normal to be with blood or to bleed, because of blood stasis small volume, therefore do not deviate from outside anus.Second phase, internal hemorrhoid was attached most importance to compared with first phase, and blood stasis is larger, and hemorrhoid mucosal tissue is weak, while exerting oneself defecation, blood stasis emerges in outside anus, can get back to voluntarily anal after an action of the bowels, during stool, excrement piece friction hemorrhoid mucomembranous surface, causes and has blood in stool, and does not have blood in stool and can be toilet paper band blood, bleeds, penetrates blood not etc.StageⅢhemorrhoid is the late stage of internal hemorrhoid.Owing to suffering from the internal hemorrhoid time longer, blood stasis increases, after an action of the bowels blood stasis emerge in anus outer, even cough, exert oneself, walk and also can emerge in outside anus during work, must send anal back to hands, or just can send anal back to after rest.
StageⅢhemorrhoid is first phase the most serious in hemorrhoid, and patient's Zhi core when defecation can be deviate from outside anus, and the cardinal symptom of stageⅢhemorrhoid shows as: 1. have blood in stool: in defecation or hemorrhage after an action of the bowels, color is scarlet, sometimes stool surface has a small amount of blood, or toilet paper is incarnadined, sometimes for bleeding or penetrating blood.Due to feces galling mucosa, or too exert oneself during because of defecation, intravascular pressure increases, so that cirso-angiorrhexis, has spurting hemorrhage in the time of just.2. deviate from: because blood stasis volume increases, being subject to the extruding of feces during defecation, making it separated with flesh layer and deviate from outside anus gradually, is that 1--2 blood stasis is deviate from sometimes simultaneously, be whole blood stasis sometimes and deviate from simultaneously with mucous membrane of rectum.Only when defecation, deviate from first, after an action of the bowels can self-resetting.Symptom, compared with severe one, needs to return with hand push after deviating from, or lies up, and can reset.Serious symptom person, deviating from during except defecation, all firmly, walking, cough, sneeze, squat down etc., all may deviate from.3. pain: simple internal hemorrhoid, generally without pain, sometimes only feel podex falling inflation or difficult defecation.As inflammation struttuer, in hemorrhoid, there are thrombosis or incarceration, there is pain; As deviate from not reset person in time, pain increases the weight of; As there is incarceration, and there is the necrosis of festering, cause anus edge inflammation edema, sharp ache, patient's uneasy in either sitting or lying.4. mucus flows out: mucous membrane of rectum is subject to the stimulation of blood stasis for a long time, causes secretions increase; Late period, internal hemorrhoid, because of Sphincter ani chalasia, often had secretions to be flowed out by anus.When the lighter defecates, flow out, severe one does not flow out during defecation naturally yet, pollutes underwear, and patient is extremely inconvenient.When internal hemorrhoid is deviate from, secretions is more.5. pruritus: because of secretions or the stimulation of deviating from blood stasis, make anus moist unclean around, eczema and pruritus occur, scratch where it itches sometimes because internal hemorrhoid is deviate from and caused because of reflection.
At present, the method for known treatment hemorrhoid has: pharmacotherapy, operative therapy and other therapies.Other therapies comprise again drug injection therapy, cryotherapy, laser therapy and infrared therapy.But in existing these Therapeutic Method, pharmacotherapy is only applicable to the patient that the state of an illness is lighter, more serious for three phase patient internal hemorrhoid, though the method is effective, can not effect a radical cure; Operative therapy and other therapies, mainly by cutting method treatment, adopt excision method to have wound, and recover slow, and some operations also can cause certain sequela after surgery, and operation more complicated, is not suitable for Most patients.Therefore, develop a kind of medicine tool for stageⅢhemorrhoid and be of great significance, and Chinese medicine has certain advantage aspect treatment stageⅢhemorrhoid, evident in efficacy.
Publication number is CN 101229257A(application number 200810009070.8) Chinese patent literature a kind of by name " the fumigation and wash method hip bath preparation that the outer incarceration of a kind of external curing stageⅢhemorrhoid core anus resets " disclosed, it is comprised of medical materials such as HUTUISHU root, full Folium Callicarpae Formosanae, Alumen, Natrii Sulfas, Cortex Phellodendri, Herba Equiseties Hiemalis.Application publication number is CN 103520247A(application number 201310529089.6) Chinese patent literature a kind of by name " a kind of traditional Chinese medical science prescription of specially controlling internal hemorrhoid " disclosed, it is characterized in that, Radix Arnebiae (Radix Lithospermi) two kind active Chinese medicine ingredients young by mouse form, the adjuvants such as this composition and gelatin, glycerol, water mix, and make suppository use through mold technique.Granted publication number is CN 102178790B(application number 201110084123.4) Chinese patent literature a kind of " a kind of suppository that is used for the treatment of hemorrhoids " by name is disclosed, this suppository is, according to weight proportion, Flos Sophorae, Herba Schizonepetae (parched), Herba Potentillae Chinensis, Cortex cercis chinensis, Viola arcuata, the Radix Angelicae Dahuricae, Flos Lonicerae, Radix Angelicae Sinensis, Cortex Phellodendri, Radix Arnebiae (Radix Lithospermi) are made to powder, and fully mixes with Borneolum Syntheticum, polyoxyethylene sorbitan monoleate, lanoline, sorbitol, monopalmitate, semi-synthetic fatty acid glyceride, 95% ethanol that rear injection suppository bag obtains.
In a word, Chinese medicine is being obtained certain achievement aspect treatment internal hemorrhoid, but also has some problems: special less for the medicine of stageⅢhemorrhoid at present, and therapeutic effect is not obvious, some medicine reduces slower, also can bring certain side effect, therefore need to improve perfect.
Summary of the invention
For the deficiencies in the prior art, one of object of the present invention is to provide a kind of stageⅢhemorrhoid reducing swelling and alleviating pain Chinese medicinal formulae evident in efficacy, easy to use, the effect with blood circulation promoting and blood stasis dispelling, anti-inflammatory analgetic, determined curative effect and without any side effects, can well make up above-mentioned deficiency.
Another object of the present invention is to provide the preparation method of above-mentioned stageⅢhemorrhoid reducing swelling and alleviating pain Chinese medicinal formulae.
Technical scheme of the present invention is:
StageⅢhemorrhoid reducing swelling and alleviating pain Chinese medicinal formulae, takes off the primary raw material of stating weight proportion and is prepared from: Radix Rehmanniae 15-35 part, Rhizoma Coptidis 3-9 part, Rhizoma Cimicifugae 3-6 part, Semen Pruni (stir-fry) 6-15 part, Fructus Sophorae 6-12 part, Herba Schizonepetae 6-15 part, Radix Cynanchi Paniculati 8-12 part, charred Radix Sanguisorbae 30-50 part, Pericarpium Papaveris (vinegar stir-fry) 5-15 part, Fructus Psoraleae 9-16 part, Fructus Amomi 5-12 part, Radix Paeoniae Alba 3-9 part, Herba Portulacae 18-30 part.
StageⅢhemorrhoid reducing swelling and alleviating pain Chinese medicinal formulae, preferred scheme is, takes off the primary raw material of stating weight proportion and is prepared from: Radix Rehmanniae 20-30 part, Rhizoma Coptidis 5-7 part, Rhizoma Cimicifugae 4-5 part, Semen Pruni (stir-fry) 9-12 part, Fructus Sophorae 8-10 part, Herba Schizonepetae 9-11 part, Radix Cynanchi Paniculati 9-11 part, charred Radix Sanguisorbae 35-45 part, Pericarpium Papaveris (vinegar stir-fry) 8-12 part, Fructus Psoraleae 11-15 part, Fructus Amomi 7-10 part, Radix Paeoniae Alba 4-7 part, Herba Portulacae 22-26 part.
StageⅢhemorrhoid reducing swelling and alleviating pain Chinese medicinal formulae, the scheme being more preferably is, takes off the primary raw material of stating weight proportion and is prepared from: 25 parts, the Radix Rehmanniae, 6 parts of Rhizoma Coptidis, 4.5 parts of Rhizoma Cimicifugaes, 10 parts of Semen Prunis (stir-fry), 9 parts of the Fructuss Sophorae, 10 parts of Herba Schizonepetae, 10 parts of Radix Cynanchi Paniculatis, 40 parts of charred Radix Sanguisorbae, 10 parts of Pericarpium Papaveriss (vinegar stir-fry), 13 parts of Fructus Psoraleaes, 8 parts of Fructus Amomis, 6 parts of Radix Paeoniae Alba, 24 parts of Herba Portulacaes.
The preparation method of above-mentioned stageⅢhemorrhoid reducing swelling and alleviating pain Chinese medicinal formulae, preparation process is as follows:
(1) Radix Rehmanniae, Rhizoma Cimicifugae, the Fructus Sophorae and Radix Cynanchi Paniculati are placed in to Oleum Sesami and soak 12-20 hour, with marmite, with slow fire, boil 20-60 minute, boil to micro-withered, oil dripping Cheng Zhuwei degree, endure afterwards that to wait medicine oil temperature to be down to 30 ℃ of elimination medicinal residues standby;
(2) Semen Pruni (stir-fry), charred Radix Sanguisorbae and Pericarpium Papaveris (vinegar stir-fry) mixed powder is broken into fine powder, crosses 95-115 mesh sieve;
(3) will Rhizoma Coptidis, Herba Schizonepetae, Fructus Psoraleae, Fructus Amomi, Radix Paeoniae Alba and Herba Portulacae decoct with water twice after mixing, water consumption be crude drug gross weight 3-6 doubly, 1.4-2 hour for the first time, 0.6-1 hour for the second time, collecting decoction, filters, and it is 1.10(45 ℃ that filtrate is concentrated into relative density) clear paste;
(4) step (1)-(3) gains are mixed, stir, be concentrated in right amount, obtain Chinese medicinal formulae unguentum.
The preparation method of above-mentioned stageⅢhemorrhoid reducing swelling and alleviating pain Chinese medicinal formulae, preferred scheme is that step (1) is placed in Oleum Sesami and soaks 14-18 hour (preferably 16 hours).
The preparation method of above-mentioned stageⅢhemorrhoid reducing swelling and alleviating pain Chinese medicinal formulae, preferred scheme is that step (1) boils 30-50 minute (preferably 40 minutes) with marmite with slow fire.
The preparation method of above-mentioned stageⅢhemorrhoid reducing swelling and alleviating pain Chinese medicinal formulae, preferred scheme is that step (2) is crossed 100-110 mesh sieve (preferably 105 mesh sieves).
The preparation method of above-mentioned stageⅢhemorrhoid reducing swelling and alleviating pain Chinese medicinal formulae, preferred scheme is that step (3) water consumption is 4-5 times (preferably 4.5 times) of crude drug gross weight.
The preparation method of above-mentioned stageⅢhemorrhoid reducing swelling and alleviating pain Chinese medicinal formulae, preferably scheme is, step (3) 1.6-1.8 hour for the first time (preferably 1.7 hours).
The preparation method of above-mentioned stageⅢhemorrhoid reducing swelling and alleviating pain Chinese medicinal formulae, preferably scheme is, step (3) 0.7-0.9 hour for the second time (preferably 0.8 hour).
Best using method: for making the present invention reach best therapeutic effect, make unguentum, every day 2 times, be applied in right amount affected part, 7 days courses for the treatment of in sooner or later getting.
The pharmacological effect of each crude drug is respectively:
The Radix Rehmanniae: another name Radix Rehmanniae is the tuber of scrophulariaceae rehmannia glutinosa plant.Nature and flavor: sweet in the mouth, cold.Gui Jing: GUIXIN, liver, kidney channel.Effect: there is clearing away heat and cooling blood effect for the warm febrile disease blood of joining the army, high fever coma, xerostomia crimson tongue.Cure mainly: can be used for controlling the warm febrile disease blood of joining the army, heat in blood poison is contained, hematemesis and epistaxis, macule purple is black.
Rhizoma Coptidis: base is former: be the dry rhizome of ranunculaceae plant Rhizoma Coptidis, Coptis deltoidea C.Y.Cheng et Hsiao or Coptis Teeta Wall.Nature and flavor: hardship, cold.Gui Jing: GUIXIN, spleen, stomach, liver, gallbladder, large intestine channel.Effect: heat clearing and damp drying, eliminating fire and detoxication.Cure mainly: for cold and heat, tie mutually damp and hot middle resistance, feeling of fullness vomiting.Cornel Rhizoma Coptidis soothing liver-QI stomach function regulating preventing or arresting vomiting.For incoordination between the liver and stomach, vomiting acid regurgitation.
Rhizoma Cimicifugae: base is former: be the dry rhizome of ranunculaceae plant C.heracleifolia, Cimicifuga Dahurica or Rhizoma Cimicifugae.Nature and flavor: pungent, micro-sweet, be slightly cold.Gui Jing: return lung, spleen, stomach, large intestine channel.Effect: deliver rash, heat-clearing and toxic substances removing, elevate a turnable ladder yang-energy.Cure mainly: for headache due to pathogenic wind-heat, toothache, aphtha, laryngopharynx swelling and pain, measles without adequate eruption, YANG toxin syndrome is sent out speckle; Proctoptosis, uterine prolapse.
Semen Pruni: base is former: be the dry mature seed of rosaceous plant Prunus humilis, strongly fragrant Lee or Prunus pedunculata Maxim..Nature and flavor: acrid in the mouth, bitter, sweet, flat.Gui Jing: return spleen, large intestine, small intestine meridian.Effect: moisturize laxation, the therapeutic method to keep the adverse QI flowing downwards, diuretic.Cure mainly: for intestine-dryness due to consumption of fluid, stagnation of QI due to dyspepsia, abdominal distention constipation, edema, beriberi, dysuria.
The Fructus Sophorae: base is former: this product is the dry mature fruit of leguminous plant Chinese scholartree.Nature and flavor: hardship, cold.Gui Jing: return liver, large intestine channel.Effect: clearing away heat-fire, cooling blood for hemostasis.Cure mainly: for intestinal heat, have blood in stool, hemorrhoid are swollen hemorrhage, liver-heat headache, dizzy conjunctival congestion.
Herba Schizonepetae: base is former: this product is the dry aerial parts of labiate Herba Schizonepetae.Nature and flavor: acrid in the mouth, tepor.Gui Jing: return lung, Liver Channel.Effect: the loose wind that induces sweat, rash.Cure mainly: for flu, headache, measles, rubella, skin infection from the beginning of.
Radix Cynanchi Paniculati: base is former: this product is the dry root and rhizome of asclepiadaceae plant Radix Cynanchi Paniculati.Nature and flavor: pungent, temperature.Gui Jing: return liver, stomach warp.Effect: the removing dampness of dispeling the wind, antalgesic-antipruritic.Cure mainly: for rheumatic arthralgia, stomachache distension, toothache, lumbago, injury from falling down; Urticaria, eczema.
Charred Radix Sanguisorbae: be the root of rosaceous plant Radix Sanguisorbae or the Radix Sanguisorbae that comes into leaves.Nature and flavor: bitter in the mouth, acid; Cold; Nontoxic.Gui Jing: return liver, lung, kidney, large intestine channel.Effect: cooling blood for hemostasis, heat-clearing and toxic substances removing.Cure mainly: control haematemesis, epistaxis, dysentery, metrorrhagia, hemorrhoidal hamorrhage, anal fistula, carbuncle, eczema, incised wound, burn.
Pericarpium Papaveris: base is former: be the drying and ripening shell of bloodroot Semen Papaveris.Nature and flavor: sour in the mouth, puckery is flat; Poisonous.Gui Jing: return lung, large intestine, kidney channel.Effect: astringe the lung, astringing intestine to stop diarrhea, pain relieving.Cure mainly: for chronic cough, chronic diarrhea, proctoptosis, epigastric pain.
Fructus Psoraleae: base is former: be the dry mature fruit of legumes psoraleae.Nature and flavor: pungent, bitter, temperature.Gui Jing: return kidney, spleen channel.Effect: warming the kidney to activate YANG, improving inspiration by invigorating kidney-QI, antidiarrheal.Cure mainly: for impotence and seminal emission, enuresis frequent micturition, chills and pain of the waist and kness, suffers from a deficiency of the kidney and breathes heavily, Diarrhoea; External curing vitiligo, alopecia areata.
Fructus Amomi: base is former: this product is the dry mature fruit of zingiberaceous plant Fructus Amomi, green shell sand or SEMEN AMOMI LONGILIGULA.Nature and flavor: pungent, temperature.Gui Jing: return board, stomach, kidney channel.Effect: removing dampness appetizing, warming spleen and stopping diarrha, regulate the flow of vital energy antiabortive.Cure mainly: for turbid damp obstructing in middle-JIAO, gastral cavity painful abdominal mass is not hungry, Deficiency and coldness of spleen and stomach, vomiting is had loose bowels, pregnancy reactions, frequent fetal movement.
Radix Paeoniae Alba: another name: milli Chinese herbaceous peony, CHUANSHAO.Base is former: originate as the root of ranunculaceae plant Radix Paeoniae.Nature and flavor: cold nature, bitter in the mouth, acid.Effect: easing the affected liver to relieve pain: dizzy for the headache that deficiency of liver-YIN liver-yang is high, often join Flos Chrysanthemi.Cure mainly: for irritability, do not give up flank pain and the contracture of the limbs causing.Nourishing blood for regulating menstruation: for cards such as blood deficiency menoxenia, metrorrhagias, often join Radix Angelicae Sinensis, Radix Rehmanniae Preparata, Rhizoma Chuanxiong.
Herba Portulacae: base is former: be the dry aerial parts of portulacaceous plant Herba Portulacae.Nature and flavor: acid, cold.Gui Jing: return liver, large intestine channel.Effect: heat-clearing and toxic substances removing, cooling blood for hemostasis.Cure mainly: for toxic-heat and blood stasis, carbuncle furuncle, eczema, erysipelas, snake bite and insect sting, has blood in stool, hemorrhoidal bleeding, metrostaxis.
Chinese medicinal formulae prescription science of the present invention, safe and effective, there is the effect of reducing swelling and alleviating pain, promoting blood circulation and hemostasis, softening Zhi core, instant effect not only, and do not recur after controlling.
The specific embodiment
Below in conjunction with embodiment and experimental example, describe technical scheme of the present invention in detail, but protection domain is not by this restriction.
embodiment 1stageⅢhemorrhoid reducing swelling and alleviating pain Chinese medicinal formulae, takes off the primary raw material of stating weight proportion and is prepared from (getting 10g for every part): 15 parts, the Radix Rehmanniae, 3 parts of Rhizoma Coptidis, 3 parts of Rhizoma Cimicifugaes, 6 parts of Semen Prunis (stir-fry), 6 parts of the Fructuss Sophorae, 6 parts of Herba Schizonepetae, 8 parts of Radix Cynanchi Paniculatis, 30 parts of charred Radix Sanguisorbae, 5 parts of Pericarpium Papaveriss (vinegar stir-fry), 9 parts of Fructus Psoraleaes, 5 parts of Fructus Amomis, 3 parts of Radix Paeoniae Alba, 18 parts of Herba Portulacaes.
The preparation method of above-mentioned stageⅢhemorrhoid reducing swelling and alleviating pain Chinese medicinal formulae, preparation process is as follows:
(1) Radix Rehmanniae, Rhizoma Cimicifugae, the Fructus Sophorae and Radix Cynanchi Paniculati are placed in to Oleum Sesami and soak 12 hours, with marmite, with slow fire, boil 20 minutes, boil to micro-withered, oil dripping Cheng Zhuwei degree, endure afterwards that to wait medicine oil temperature to be down to 30 ℃ of elimination medicinal residues standby;
(2) Semen Pruni (stir-fry), charred Radix Sanguisorbae and Pericarpium Papaveris (vinegar stir-fry) mixed powder is broken into fine powder, crosses 95 mesh sieves;
(3) will after Rhizoma Coptidis, Herba Schizonepetae, Fructus Psoraleae, Fructus Amomi, Radix Paeoniae Alba and Herba Portulacae mixing, decoct with water twice, water consumption is 3 times of crude drug gross weight, 1.4 hours for the first time, 0.6 hour for the second time, collecting decoction, filters, and it is 1.10(45 ℃ that filtrate is concentrated into relative density) clear paste;
(4) step (1)-(3) gains are mixed, stir, be concentrated in right amount, obtain Chinese medicinal formulae unguentum.
model case one:lu XX, female, 37 years old.Patient's readme symptom of having blood in stool for the first time last year, starts not take notice of, after increase the weight of gradually, anus place pruritus is abnormal, so go to community hospital to check, is diagnosed as hemorrhoid, bring back some suppositorys, start effectively, rear effect is variation gradually, and blood flows more and more, and when stool Zhi core can deviate from outside anus, Hui Na, removes examination in hospital voluntarily, is diagnosed as stageⅢhemorrhoid.Use the present embodiment 1 gained stageⅢhemorrhoid reducing swelling and alleviating pain Chinese medicinal formulae, adopt every day 2 times, in sooner or later getting, be applied in right amount affected part, 7 days courses for the treatment of.Use 3 days, patient's symptom of having blood in stool alleviates, and anus place pruritus disappears; Use 5 days, patient's malaise symptoms is clearly better, and partial symptoms disappears; Continue to use 2 days the recovery from illness of patient's self-induction.
embodiment 2stageⅢhemorrhoid reducing swelling and alleviating pain Chinese medicinal formulae, takes off the primary raw material of stating weight proportion and is prepared from (getting 20g for every part): 35 parts, the Radix Rehmanniae, 9 parts of Rhizoma Coptidis, 6 parts of Rhizoma Cimicifugaes, 15 parts of Semen Prunis (stir-fry), 12 parts of the Fructuss Sophorae, 15 parts of Herba Schizonepetae, 12 parts of Radix Cynanchi Paniculatis, 50 parts of charred Radix Sanguisorbae, 15 parts of Pericarpium Papaveriss (vinegar stir-fry), 16 parts of Fructus Psoraleaes, 12 parts of Fructus Amomis, 9 parts of Radix Paeoniae Alba, 30 parts of Herba Portulacaes.
The preparation method of above-mentioned stageⅢhemorrhoid reducing swelling and alleviating pain Chinese medicinal formulae, preparation process is as follows:
(1) Radix Rehmanniae, Rhizoma Cimicifugae, the Fructus Sophorae and Radix Cynanchi Paniculati are placed in to Oleum Sesami and soak 20 hours, with marmite, with slow fire, boil 60 minutes, boil to micro-withered, oil dripping Cheng Zhuwei degree, endure afterwards that to wait medicine oil temperature to be down to 30 ℃ of elimination medicinal residues standby;
(2) Semen Pruni (stir-fry), charred Radix Sanguisorbae and Pericarpium Papaveris (vinegar stir-fry) mixed powder is broken into fine powder, crosses 115 mesh sieves;
(3) will after Rhizoma Coptidis, Herba Schizonepetae, Fructus Psoraleae, Fructus Amomi, Radix Paeoniae Alba and Herba Portulacae mixing, decoct with water twice, water consumption is 6 times of crude drug gross weight, 2 hours for the first time, 1 hour for the second time, collecting decoction, filters, and it is 1.10(45 ℃ that filtrate is concentrated into relative density) clear paste;
(4) step (1)-(3) gains are mixed, stir, be concentrated in right amount, obtain Chinese medicinal formulae unguentum.
embodiment 3stageⅢhemorrhoid reducing swelling and alleviating pain Chinese medicinal formulae, takes off the primary raw material of stating weight proportion and is prepared from (getting 30g for every part): 20 parts, the Radix Rehmanniae, 5 parts of Rhizoma Coptidis, 4 parts of Rhizoma Cimicifugaes, 9 parts of Semen Prunis (stir-fry), 8 parts of the Fructuss Sophorae, 9 parts of Herba Schizonepetae, 9 parts of Radix Cynanchi Paniculatis, 35 parts of charred Radix Sanguisorbae, 8 parts of Pericarpium Papaveriss (vinegar stir-fry), 11 parts of Fructus Psoraleaes, 7 parts of Fructus Amomis, 4 parts of Radix Paeoniae Alba, 22 parts of Herba Portulacaes.
The preparation method of above-mentioned stageⅢhemorrhoid reducing swelling and alleviating pain Chinese medicinal formulae, preparation process is as follows:
(1) Radix Rehmanniae, Rhizoma Cimicifugae, the Fructus Sophorae and Radix Cynanchi Paniculati are placed in to Oleum Sesami and soak 14 hours, with marmite, with slow fire, boil 30 minutes, boil to micro-withered, oil dripping Cheng Zhuwei degree, endure afterwards that to wait medicine oil temperature to be down to 30 ℃ of elimination medicinal residues standby;
(2) Semen Pruni (stir-fry), charred Radix Sanguisorbae and Pericarpium Papaveris (vinegar stir-fry) mixed powder is broken into fine powder, crosses 100 mesh sieves;
(3) will after Rhizoma Coptidis, Herba Schizonepetae, Fructus Psoraleae, Fructus Amomi, Radix Paeoniae Alba and Herba Portulacae mixing, decoct with water twice, water consumption is 4 times of crude drug gross weight, 1.6 hours for the first time, 0.7 hour for the second time, collecting decoction, filters, and it is 1.10(45 ℃ that filtrate is concentrated into relative density) clear paste;
(4) step (1)-(3) gains are mixed, stir, be concentrated in right amount, obtain Chinese medicinal formulae unguentum.
model case two: grandson XX, man, 45 years old.It is more difficult that patient closely feels defecation, and anus place pruritus abnormal, have pain, during defecation, have bloodstain in just, color is scarlet, has once in a while the symptom of bleeding, and feels sometimes have a meat to deviate from from anus, Mr. Sun fears very much, so remove examination in hospital, is diagnosed as stageⅢhemorrhoid.Use the present embodiment 3 gained stageⅢhemorrhoid reducing swelling and alleviating pain Chinese medicinal formulaes, adopt every day 2 times, in sooner or later getting, be applied in right amount affected part, 7 days courses for the treatment of.Use 2 days, patient's anus place pruritus transference cure, the symptom of having blood in stool takes a turn for the better; Use 5 days, patient's malaise symptoms obviously improves, and pain disappears; Continue to use 3 days, patient's malaise symptoms disappears completely, does not occur any discomfort symptom between the operating period.
embodiment 4stageⅢhemorrhoid reducing swelling and alleviating pain Chinese medicinal formulae, takes off the primary raw material of stating weight proportion and is prepared from (getting 40g for every part): 30 parts, the Radix Rehmanniae, 7 parts of Rhizoma Coptidis, 5 parts of Rhizoma Cimicifugaes, 12 parts of Semen Prunis (stir-fry), 10 parts of the Fructuss Sophorae, 11 parts of Herba Schizonepetae, 11 parts of Radix Cynanchi Paniculatis, 45 parts of charred Radix Sanguisorbae, 12 parts of Pericarpium Papaveriss (vinegar stir-fry), 15 parts of Fructus Psoraleaes, 10 parts of Fructus Amomis, 7 parts of Radix Paeoniae Alba, 26 parts of Herba Portulacaes.
The preparation method of above-mentioned stageⅢhemorrhoid reducing swelling and alleviating pain Chinese medicinal formulae, preparation process is as follows:
(1) Radix Rehmanniae, Rhizoma Cimicifugae, the Fructus Sophorae and Radix Cynanchi Paniculati are placed in to Oleum Sesami and soak 18 hours, with marmite, with slow fire, boil 50 minutes, boil to micro-withered, oil dripping Cheng Zhuwei degree, endure afterwards that to wait medicine oil temperature to be down to 30 ℃ of elimination medicinal residues standby;
(2) Semen Pruni (stir-fry), charred Radix Sanguisorbae and Pericarpium Papaveris (vinegar stir-fry) mixed powder is broken into fine powder, crosses 110 mesh sieves;
(3) will after Rhizoma Coptidis, Herba Schizonepetae, Fructus Psoraleae, Fructus Amomi, Radix Paeoniae Alba and Herba Portulacae mixing, decoct with water twice, water consumption is 5 times of crude drug gross weight, 1.8 hours for the first time, 0.9 hour for the second time, collecting decoction, filters, and it is 1.10(45 ℃ that filtrate is concentrated into relative density) clear paste;
(4) step (1)-(3) gains are mixed, stir, be concentrated in right amount, obtain Chinese medicinal formulae unguentum.
model case three: Wu XX, female, 24 years old.The creative design of patient Wei Yi company, goes to work extremely busy at ordinary times, and pressure is very large, recently, Miss Wu finds that the health of oneself is out of joint: since last week, her stool is very dry, always gruelling during defecation, anus place is pain very, also has bloodstain in stool, several days have been spent, aggravation, the symptom of bleeding during defecation, and Zhi core can be deviate from outside anus, need to remove examination in hospital with in hand push ex vivo, be diagnosed as stageⅢhemorrhoid.Use the present embodiment 4 gained stageⅢhemorrhoid reducing swelling and alleviating pain Chinese medicinal formulaes, adopt every day 2 times, in sooner or later getting, be applied in right amount affected part, 7 days courses for the treatment of.Use 3 days, patient's symptom of having blood in stool is improved, pain relief; Use 7 days, patient's malaise symptoms obviously improves, and Zhi core is deviate from transference cure; Continue to use 3 days the recovery from illness of patient's self-induction.
embodiment 5stageⅢhemorrhoid reducing swelling and alleviating pain Chinese medicinal formulae, takes off the primary raw material of stating weight proportion and is prepared from (getting 50g for every part): 25 parts, the Radix Rehmanniae, 6 parts of Rhizoma Coptidis, 4.5 parts of Rhizoma Cimicifugaes, 10 parts of Semen Prunis (stir-fry), 9 parts of the Fructuss Sophorae, 10 parts of Herba Schizonepetae, 10 parts of Radix Cynanchi Paniculatis, 40 parts of charred Radix Sanguisorbae, 10 parts of Pericarpium Papaveriss (vinegar stir-fry), 13 parts of Fructus Psoraleaes, 8 parts of Fructus Amomis, 6 parts of Radix Paeoniae Alba, 24 parts of Herba Portulacaes.
The preparation method of above-mentioned stageⅢhemorrhoid reducing swelling and alleviating pain Chinese medicinal formulae, preparation process is as follows:
(1) Radix Rehmanniae, Rhizoma Cimicifugae, the Fructus Sophorae and Radix Cynanchi Paniculati are placed in to Oleum Sesami and soak 16 hours, with marmite, with slow fire, boil 40 minutes, boil to micro-withered, oil dripping Cheng Zhuwei degree, endure afterwards that to wait medicine oil temperature to be down to 30 ℃ of elimination medicinal residues standby;
(2) Semen Pruni (stir-fry), charred Radix Sanguisorbae and Pericarpium Papaveris (vinegar stir-fry) mixed powder is broken into fine powder, crosses 105 mesh sieves;
(3) will after Rhizoma Coptidis, Herba Schizonepetae, Fructus Psoraleae, Fructus Amomi, Radix Paeoniae Alba and Herba Portulacae mixing, decoct with water twice, water consumption is 4.5 times of crude drug gross weight, 1.7 hours for the first time, 0.8 hour for the second time, collecting decoction, filters, and it is 1.10(45 ℃ that filtrate is concentrated into relative density) clear paste;
(4) step (1)-(3) gains are mixed, stir, be concentrated in right amount, obtain Chinese medicinal formulae unguentum.
experimental example 1the clinical practice of embodiment 5 gained stageⅢhemorrhoid reducing swelling and alleviating pain Chinese medicinal formulaes: in July, 2007-2009 year JIUYUE, in 6 hospitals, screen 180 routine patients, women's 94 examples wherein, male's 86 examples.Test 3 days before, carries out Continuous Observation to this crowd, records symptom and variation, be divided at random two groups, experimental group and matched group, experimental group is taken embodiment 5 products obtained therefroms, and matched group is taken other medicine conventional medicines such as () HUAZHI SHUAN, MAYINGLONGZHICHUANGGAO, the peaceful sheets of hemorrhoid speed.Using method is: every day 2 times, in sooner or later getting, be applied in right amount affected part, 7 days courses for the treatment of.Curative effect situation criterion: cure: use a course for the treatment of of this product, have blood in stool, the disease such as pain disappears, malaise symptoms disappears completely; Effective: use a course for the treatment of of this product, malaise symptoms alleviates or part disappears; Invalid: use a course for the treatment of of this product, malaise symptoms is unchanged.Result is as shown in table 1.
The compliance test result of table 1: embodiment 5 gained stageⅢhemorrhoid reducing swelling and alleviating pain Chinese medicinal formulaes
Therapeutic effect: cure 70 examples (70%), effective 26 examples (26%), invalid 4 examples (4%), total effective rate 96%.Successful is better than matched group.
Between the operating period, self-induction symptom and other symptom variation are as shown in table 2.
Table 2:
Oleum Sesami has the effect of loosening bowel to relieve constipation, removing toxic substances, granulation promoting, can effectively treat dryness of the intestine constipation, ulcer, skin ulcer swollen etc.Chinese medicinal formulae of the present invention selects Oleum Sesami to soak medicine, is more conducive to bring into play the effect of Oleum Sesami, and stageⅢhemorrhoid is had to better therapeutic effect.Use 2 days, more than 56% patient's symptom is improved, pain relief, and Zhi core is deviate from transference cure; Use 5 days, more than 76% patient's malaise symptoms improves, pain relief, and the symptom of having blood in stool disappears substantially; Use 7 days, more than 97% patient's malaise symptoms improves, and has blood in stool, the disease such as pain obviously improves, the recovery from illness of some patients were self-induction.Experimental group is used 7 days, and effective percentage can reach 97%, and matched group is only 80%.
Finally it should be noted that, embodiment is the specific embodiment of optimum of the present invention, be not limited to the present invention, although the present invention is had been described in detail with reference to previous embodiment, for a person skilled in the art, its technical scheme that still can record aforementioned each embodiment is modified, or part technical characterictic is wherein equal to replacement.Within the spirit and principles in the present invention all, any modification of doing, be equal to replacement, improvement etc., within all should being included in protection scope of the present invention.
Claims (10)
1. stageⅢhemorrhoid reducing swelling and alleviating pain Chinese medicinal formulae, is characterized in that, takes off the primary raw material of stating weight proportion and is prepared from: Radix Rehmanniae 15-35 part, Rhizoma Coptidis 3-9 part, Rhizoma Cimicifugae 3-6 part, Semen Pruni (stir-fry) 6-15 part, Fructus Sophorae 6-12 part, Herba Schizonepetae 6-15 part, Radix Cynanchi Paniculati 8-12 part, charred Radix Sanguisorbae 30-50 part, Pericarpium Papaveris (vinegar stir-fry) 5-15 part, Fructus Psoraleae 9-16 part, Fructus Amomi 5-12 part, Radix Paeoniae Alba 3-9 part, Herba Portulacae 18-30 part.
2. stageⅢhemorrhoid reducing swelling and alleviating pain Chinese medicinal formulae according to claim 1, is characterized in that, takes off the primary raw material of stating weight proportion and is prepared from: Radix Rehmanniae 20-30 part, Rhizoma Coptidis 5-7 part, Rhizoma Cimicifugae 4-5 part, Semen Pruni (stir-fry) 9-12 part, Fructus Sophorae 8-10 part, Herba Schizonepetae 9-11 part, Radix Cynanchi Paniculati 9-11 part, charred Radix Sanguisorbae 35-45 part, Pericarpium Papaveris (vinegar stir-fry) 8-12 part, Fructus Psoraleae 11-15 part, Fructus Amomi 7-10 part, Radix Paeoniae Alba 4-7 part, Herba Portulacae 22-26 part.
3. stageⅢhemorrhoid reducing swelling and alleviating pain Chinese medicinal formulae according to claim 1, is characterized in that, takes off the primary raw material of stating weight proportion and is prepared from: 25 parts, the Radix Rehmanniae, 6 parts of Rhizoma Coptidis, 4.5 parts of Rhizoma Cimicifugaes, 10 parts of Semen Prunis (stir-fry), 9 parts of the Fructuss Sophorae, 10 parts of Herba Schizonepetae, 10 parts of Radix Cynanchi Paniculatis, 40 parts of charred Radix Sanguisorbae, 10 parts of Pericarpium Papaveriss (vinegar stir-fry), 13 parts of Fructus Psoraleaes, 8 parts of Fructus Amomis, 6 parts of Radix Paeoniae Alba, 24 parts of Herba Portulacaes.
4. according to the preparation method of the arbitrary described stageⅢhemorrhoid reducing swelling and alleviating pain Chinese medicinal formulae of claim 1-3, it is characterized in that, step is as follows:
(1) Radix Rehmanniae, Rhizoma Cimicifugae, the Fructus Sophorae and Radix Cynanchi Paniculati are placed in to Oleum Sesami and soak 12-20 hour, with marmite, with slow fire, boil 20-60 minute, boil to micro-withered, oil dripping Cheng Zhuwei degree, endure afterwards that to wait medicine oil temperature to be down to 30 ℃ of elimination medicinal residues standby;
(2) Semen Pruni (stir-fry), charred Radix Sanguisorbae and Pericarpium Papaveris (vinegar stir-fry) mixed powder is broken into fine powder, crosses 95-115 mesh sieve;
(3) will Rhizoma Coptidis, Herba Schizonepetae, Fructus Psoraleae, Fructus Amomi, Radix Paeoniae Alba and Herba Portulacae decoct with water twice after mixing, water consumption be crude drug gross weight 3-6 doubly, 1.4-2 hour for the first time, 0.6-1 hour for the second time, collecting decoction, filters, and it is 1.10 clear paste that filtrate is concentrated into relative density;
(4) step (1)-(3) gains are mixed, stir, be concentrated in right amount, obtain Chinese medicinal formulae unguentum.
5. preparation method according to claim 4, is characterized in that: step (1) is placed in Oleum Sesami and soaks 14-18 hour (preferably 16 hours).
6. preparation method according to claim 4, is characterized in that: step (1) boils 30-50 minute (preferably 40 minutes) with marmite with slow fire.
7. preparation method according to claim 4, is characterized in that: step (2) is crossed 100-110 mesh sieve (preferably 105 mesh sieves).
8. preparation method according to claim 4, is characterized in that: step (3) water consumption is 4-5 times (preferably 4.5 times) of crude drug gross weight.
9. preparation method according to claim 4, is characterized in that: step (3) 1.6-1.8 hour for the first time (preferably 1.7 hours).
10. preparation method according to claim 4, is characterized in that: step (3) 0.7-0.9 hour for the second time (preferably 0.8 hour).
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Address after: Zigong City, Sichuan Province, the 643000 academy Street ginkgo Ziliujing District District 9 building room 1-102 Applicant after: Yang Qiuyue Address before: 250014 Shandong Province, Lixia District of Ji'nan city jiangshuiquan Road No. 1 jichai nine dormitory 3 floor 1 unit 201 Applicant before: Yang Qiuyue |
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