CN104042788A - Traditional Chinese medicine composition for treating thromboangitis obliterans - Google Patents

Traditional Chinese medicine composition for treating thromboangitis obliterans Download PDF

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CN104042788A
CN104042788A CN201410298507.XA CN201410298507A CN104042788A CN 104042788 A CN104042788 A CN 104042788A CN 201410298507 A CN201410298507 A CN 201410298507A CN 104042788 A CN104042788 A CN 104042788A
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chinese medicine
medicine composition
radix
herba
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CN104042788B (en
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张金龙
邱金胜
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Yang Zhili
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Abstract

The invention discloses a traditional Chinese medicine composition for treating thromboangitis obliterans. The traditional Chinese medicine composition is prepared from the following crude drugs in parts by weight: 10-20 parts of salvia miltiorrhiza, 5-10 parts of honeysuckle, 5-10 parts of dandelion, 5-10 parts of deep-fried white atractylodes rhizome, 8-12 parts of leech, 8-15 parts of viola, 10-20 parts of panax notoginseng, 8-12 parts of gecko and 10-20 parts of radix scrophulariae. The selected crude drugs simultaneously take the effects of promoting coronary circulation, clearing away heat and toxic materials, tonifying qi and dispelling dampness, relieving swelling and pain as well as invigorating spleen and supplementing qi and the like. Through clinical application, the traditional Chinese medicine composition is found to have the advantages of rapidness in taking effects, good drug effect, low cost and no any toxic or side effect on the aspect of treating thromboangitis obliterans.

Description

A kind of Chinese medicine composition for the treatment of thromboangiitis obliterans
Technical field
The invention belongs to the field of Chinese medicines, specifically a kind of Chinese medicine composition that can treat thromboangiitis obliterans.
Background technology
Thromboangiitis obliterans is in a kind of rare chronic recurrent, the segmental diseases associated with inflammation of small artery and vein, and lower limb are common.Show as suffering limb ischemia, pain, intermittent claudication, pulsation of foot dorsal artery weakens or disappearance and migration Superficial phlebitis, severe patient has acra ulcer and necrosis.
Primary disease is more common in person between twenty and fifty, is apt to occur in lower limb.Suffering limb presents momentary or persistence is pale, cyanosis, have scorching hot and twinge, and when sick limb is sagging, color of the leather reddens, and during upper act, bleaches, and then toes are numb, and Calf muscle pain, excites during walking, during rest, disappears; Often there is superficial phlebitis and edema in calf.During inspection, find that pulsation of foot dorsal artery weakens or disappears.Along with intermittent claudication and Raynaud phenomenon, night pain can appear in PD.
At present, treatment thromboangiitis obliterans is mainly that long-term steroid antibiotic etc or operation are treated, although many medicine short run effects are obvious, long-term efficacy is imprecise, and price is comparatively expensive.In addition, although the operation method of thromboangiitis obliterans is more, because pathological changes is involved middle small artery more, it is desirable that surgical effect is owed, and is difficult to radical cure.Therefore, according to the principle of the traditional Chinese medical science " treating both the principal and secondary aspects of a disease ", need badly and invent to the ill a kind of Chinese medicine and treat, reach the shortening course of disease, prevent the object of chronic disease recurrence.
Summary of the invention
The invention solves at present in the defect existing aspect treatment thromboangiitis obliterans, a kind of instant effect, short treating period, Chinese medicine composition cheap and without any side effects are provided.
The technical solution adopted in the present invention is: a kind of Chinese medicine composition for the treatment of thromboangiitis obliterans, it is characterized in that, and described compositions is comprised of the Chinese herb of following weight portion:
Radix Salviae Miltiorrhizae 10-20 part, Flos Lonicerae 5-10 part, Herba Taraxaci 5-10 part, Rhizoma Atractylodis Macrocephalae preparata 5-10 part, Hirudo 8-12 part, Herba Violae 8-15 part, Radix Notoginseng 10-20 part, Gekko Swinhonis 8-12 part, Radix Scrophulariae 10-20 part.
As this kind of prioritization scheme:
Described compositions is comprised of the Chinese herb of following weight portion:
10 parts of Radix Salviae Miltiorrhizaes, 5 parts of Flos Loniceraes, 5 parts of Herba Taraxacis, 5 parts of Rhizoma Atractylodis Macrocephalae preparatas, 8 parts of Hirudos, 8 parts of Herba Violaes, 10 parts of Radix Notoginseng, 8 parts of Gekko Swinhonis, 10 parts of Radix Scrophulariaes.
As this kind of prioritization scheme:
Described compositions is comprised of the Chinese herb of following weight portion:
15 parts of Radix Salviae Miltiorrhizaes, 8 parts of Flos Loniceraes, 8 parts of Herba Taraxacis, 8 parts of Rhizoma Atractylodis Macrocephalae preparatas, 10 parts of Hirudos, 12 parts of Herba Violaes, 15 parts of Radix Notoginseng, 10 parts of Gekko Swinhonis, 15 parts of Radix Scrophulariaes.
As this kind of prioritization scheme:
Described compositions is comprised of the Chinese herb of following weight portion:
20 parts of Radix Salviae Miltiorrhizaes, 10 parts of Flos Loniceraes, 10 parts of Herba Taraxacis, 10 parts of Rhizoma Atractylodis Macrocephalae preparatas, 12 parts of Hirudos, 15 parts of Herba Violaes, 20 parts of Radix Notoginseng, 12 parts of Gekko Swinhonis, 20 parts of Radix Scrophulariaes.
The instructions of taking of above-mentioned Chinese medicine composition is: after the raw material Chinese medicine of above-mentioned weight proportion is mixed, according to the method for the fried Chinese medicine of tradition, get its medicine juice, 1 dose of every day, minute 2 clothes, 15 days are a course for the treatment of.
The raw material Chinese medicine of above-mentioned Chinese medicine composition:
Radix Salviae Miltiorrhizae, hardship, is slightly cold; Enter the heart, Liver Channel.There is blood circulation promoting and blood stasis dispelling, nourishing blood to tranquillize the mind, the effect of removing heat from blood detumescence, can effectively improve cardio-cerebrovascular.
Flos Lonicerae, cold in nature, sweet in the mouth; Attach to the lung and stomach meridians.There is heat-clearing and toxic substances removing, the effect of dispelling wind and heat pathogens.
Herba Taraxaci, property is flat, sweet in the mouth, micro-hardship; Return liver, stomach warp.There is heat-clearing and toxic substances removing, the effect of dispersing swelling and dissipating binds, row water diuresis.
Rhizoma Atractylodis Macrocephalae preparata, sweet in the mouth, hardship, warm in nature.Return spleen, stomach warp.There is invigorating the spleen and replenishing QI, dampness diuretic, the effect of strengthening superficial resistance to stop perspiration.
Hirudo, bitter in the mouth is flat; Return Liver Channel.The effect with removing blood stasis, the effect such as antithrombotic, anticoagulation obviously.
Herba Violae, taste bitter, acrid, cold; GUIXIN, Liver Channel.There is heat-clearing and toxic substances removing, the effect of removing heat from blood detumescence.
Radix Notoginseng, sweet in the mouth, micro-hardship, temperature; GUIXIN, liver, spleen channel.There is removing stasis to stop bleeding, the effect of reducing swelling and alleviating pain.
Gekko Swinhonis, salty in the mouth is cold, has expelling wind for relieving convulsion, pain relieving eliminating stagnation, the effect of removing toxic substances.
Radix Scrophulariae, bitter in the mouth, sweet, salty, cold; Return lung, stomach, kidney channel.There is clearing away heat and cooling blood, detoxicating and resolving stagnation of pathogens, the effect of Yin-nourishing and body fluid promoting.
The traditional Chinese medical science thinks, thromboangiitis obliterans is asthenia of both the spleen and kidney, YANG QI deficiency, and insufficiency of vital energy and blood, is subject to the heresy of cold-damp outward, so that qi stagnation hemagglutination, and meridians intercept, and extremity QI and blood can not be moistened foster, sends out as necrosis.So when treatment, should be with heat-clearing and toxic substances removing, promoting blood circulation to remove obstruction in the collateral, regulating YIN and YANG are this.Chinese medicine composition of the present invention, Radix Salviae Miltiorrhizae, Hirudo, Radix Notoginseng can blood circulation promoting and blood stasis dispelling, nourishing blood to tranquillize the mind, antithrombotic, blood coagulation resisting function are obvious; Flos Lonicerae, Herba Taraxaci, Herba Violae three collocation can heat-clearing and toxic substances removing, dispelling wind and heat pathogens, reducing swelling and alleviating pain; Gekko Swinhonis, Radix Scrophulariae can detoxicating and resolving stagnation of pathogens, clearing away heat and cooling blood; Rhizoma Atractylodis Macrocephalae preparata can invigorating the spleen and replenishing QI, Yin-nourishing and body fluid promoting, and QI invigorating is kept fit.All medicines are played the effects such as heat-clearing and toxic substances removing, blood circulation and channel invigorating, Yin-nourishing and body fluid promoting altogether, expansible blood vessel, and thrombus, blood circulation promoting, has good efficacy to treatment thromboangiitis obliterans.
For further investigating the clinical efficacy of medicine of the present invention, we have selected 76 routine out-patients to carry out clinical trial, male patient's 65 examples, and female patient 11 examples, age of onset is 18-67, the course of disease is 4 months-6 years.
In 76 routine patients: 2 examples of condition of illness all appear in extremity, biped patient 16 examples, left sufficient patient's 22 examples, right sufficient patient's 24 examples, 2 examples for biped first fall ill after the right hand ill, 1 routine patient falls ill for the right hand and left foot simultaneously.
Criterion of therapeutical effect:
Recovery from illness: clinical symptoms disappears substantially, and limbs wound surface heals completely, no sequel.
Effective: clinical symptoms is obviously improved, limbs wound healing or approaching healing, other is as ordinary person.
Take a turn for the better: clinical symptom relief, limbs wound surface approaches healing or dwindles.
Invalid: clinical symptoms and sign, without change, even worsen.
Therapeutic Method:
Treatment group is taken the Chinese medicine composition of embodiment 2, according to the method for the fried Chinese medicine of tradition, get its medicine juice, 1 dose of every day, divide clothes 2 times, within 15 days, be a course for the treatment of, generally need to treat 2-4 the course for the treatment of, can reach better effects, at period in a medicine, that patient avoids is pungent, peppery, greasy food and Folium Camelliae sinensis and tobacco and wine.
Clinical efficacy situation statistics is in Table one.
Treat after 3 courses for the treatment of, patient cures 58 examples, effective 9 examples, and 7 examples that take a turn for the better, invalid 2 examples (invalid patient is longer patient of course of disease time), total effective rate reaches 97.4%.
Table one: the curative effect comparision result table after two groups of case treatments
Result in table one shows, Chinese medicine composition of the present invention is evident in efficacy to chronic pelvic inflammatory disease, clinic promotion and application.
The specific embodiment
Embodiment 1: a kind of Chinese medicine composition for the treatment of thromboangiitis obliterans, choose 10 parts of Radix Salviae Miltiorrhizaes, 5 parts of Flos Loniceraes, 5 parts of Herba Taraxacis, 5 parts of Rhizoma Atractylodis Macrocephalae preparatas, 8 parts of Hirudos, 8 parts of Herba Violaes, 10 parts of Radix Notoginseng, 8 parts of Gekko Swinhonis, 10 parts of Radix Scrophulariaes.
Embodiment 2: a kind of Chinese medicine composition for the treatment of thromboangiitis obliterans, choose 15 parts of Radix Salviae Miltiorrhizaes, 8 parts of Flos Loniceraes, 8 parts of Herba Taraxacis, 8 parts of Rhizoma Atractylodis Macrocephalae preparatas, 10 parts of Hirudos, 12 parts of Herba Violaes, 15 parts of Radix Notoginseng, 10 parts of Gekko Swinhonis, 15 parts of Radix Scrophulariaes.
Embodiment 3: a kind of Chinese medicine composition for the treatment of thromboangiitis obliterans, choose 20 parts of Radix Salviae Miltiorrhizaes, 10 parts of Flos Loniceraes, 10 parts of Herba Taraxacis, 10 parts of Rhizoma Atractylodis Macrocephalae preparatas, 12 parts of Hirudos, 15 parts of Herba Violaes, 20 parts of Radix Notoginseng, 12 parts of Gekko Swinhonis, 20 parts of Radix Scrophulariaes.
Every part in above embodiment is every gram.
Below by concrete case, Chinese medicine composition curative effect of the present invention is further verified:
Case 1
Liu XX, man, 38 years old, the left foot of main cause swelled and ache more than February.In April, 2010, without obvious inducement, there is left sufficient big toe congestion and swelling pain in patient, Mou hospital is " section thromboembolism far away in two lower limb popliteal tremulous pulsies " through ultrasound diagnosis, oral cilostazol, visit aspirin tablet treatment, symptom increases the weight of gradually, red and swollen to left foot, send out cool, sharp ache.Take Chinese medicine composition of the present invention after the course for the treatment of, all diseases are clearly better, and toes swelling is disappeared, and toes action recovers, and pulsation of foot dorsal artery, without extremely, continues to take after the course for the treatment of, cure.Follow up a case by regular visits to 1 year without recurrence.
Case 2
Open XX, man, 34 years old, patient started to occur left sufficient front end pain in January, 2010, aggravates night more than 1 year.After from the first toes, in succession there is foot congestion and swelling pain, when travel distance is long, there is intermittent claudication.Pain can be stood daytime, whenever aggravation at night, has a strong impact on sleep.Through health check-up, find that left lower extremity muscular strength is normal, do not draw pathologic reflex.Second and third toe of left foot is gently swollen, and the colour of skin is dark violet, and foot end skin temperature obviously reduces.Left dorsal artery of foot ripple is beaten faint, and left posterior tibial artery is beaten normally.Upon somebody's introduction, take continuously Chinese medicine composition of the present invention after two courses for the treatment of, toes pain obviously alleviates, skin alternating temperature, and pulse is normal, can slowly walk.Continue to take after the course for the treatment of, recovery from illness, can normally walk.Follow up a case by regular visits to 2 years without recurrence.
Case 3
Lee XX, man, 42 years old, patient sent out numbness cool with left sufficient pain, and companion's three-toed festered more than January.In March, 09, when patient feels to walk without obvious inducement, vola pain takes a turn for the better after having a rest, pain reproduction while again walking, local second, can send out hospital diagnosis peripheral neuritis, invalid after medication treatment, left foot sensation is sent out cool, numb, July, the 3rd toe toe-end plays red and swollen scleroma, pain increases the weight of, after cleaning, the left foot of December three-toed finds toes blackout, pain increases the weight of, start after being introduced to take Chinese medicine composition of the present invention, after two courses for the treatment of, pain obviously alleviates, legs and feet are warm, can slowly walk, swelling is disappeared, toes color is improved gradually, continue to take two courses for the treatment of or, clinical symptoms is all cured.Follow up a case by regular visits to 1 year without recurrence.
Case 4
Zhao XX, man, 38 years old, there is two foots and right hand pain because dropping down winter after water crosses the river in patient before 3 years, the vascular hardening of bilateral instep, with right side for very.Often, to left large toes numbness in winter, by the following pain of carpus, the large little toe of right foot is sent out cool, if just walk 500m road two foot pain fiber crops unbearably.Right hand middle finger, unknown finger tip be purple darkly, the water of suppurating that festered, and pain numbness, left large finger tip is purple, sends out cool, and Jing Duojia hospital examines as vasculitis.Start after being introduced to take Chinese medicine composition of the present invention, after two courses for the treatment of, finger tip festers and greatly takes a turn for the better, the blood vessel deliquescing on outstanding instep, calm down, with having scleroma in hands tangibly blood vessel, middle finger tip rotten position has grown new meat, two foots that go on a journey also feel no pain, but still have feeling of numbness.Continue hair after two courses for the treatment of, only individually finger, toes send out send out cool, remaining disease all heals.Follow up a case by regular visits to half a year without recurrence.

Claims (4)

1. a Chinese medicine composition for the treatment of thromboangiitis obliterans, is characterized in that, described compositions is comprised of the Chinese herb of following weight portion:
Radix Salviae Miltiorrhizae 10-20 part, Flos Lonicerae 5-10 part, Herba Taraxaci 5-10 part, Rhizoma Atractylodis Macrocephalae preparata 5-10 part, Hirudo 8-12 part, Herba Violae 8-15 part, Radix Notoginseng 10-20 part, Gekko Swinhonis 8-12 part, Radix Scrophulariae 10-20 part.
2. Chinese medicine composition according to claim 1, is characterized in that, described Chinese medicine composition is comprised of the Chinese herb of following weight portion:
10 parts of Radix Salviae Miltiorrhizaes, 5 parts of Flos Loniceraes, 5 parts of Herba Taraxacis, 5 parts of Rhizoma Atractylodis Macrocephalae preparatas, 8 parts of Hirudos, 8 parts of Herba Violaes, 10 parts of Radix Notoginseng, 8 parts of Gekko Swinhonis, 10 parts of Radix Scrophulariaes.
3. Chinese medicine composition according to claim 1, is characterized in that, described Chinese medicine composition is comprised of the Chinese herb of following weight portion:
15 parts of Radix Salviae Miltiorrhizaes, 8 parts of Flos Loniceraes, 8 parts of Herba Taraxacis, 8 parts of Rhizoma Atractylodis Macrocephalae preparatas, 10 parts of Hirudos, 12 parts of Herba Violaes, 15 parts of Radix Notoginseng, 10 parts of Gekko Swinhonis, 15 parts of Radix Scrophulariaes.
4. Chinese medicine composition according to claim 1, is characterized in that, described Chinese medicine composition is comprised of the Chinese herb of following weight portion:
20 parts of Radix Salviae Miltiorrhizaes, 10 parts of Flos Loniceraes, 10 parts of Herba Taraxacis, 10 parts of Rhizoma Atractylodis Macrocephalae preparatas, 12 parts of Hirudos, 15 parts of Herba Violaes, 20 parts of Radix Notoginseng, 12 parts of Gekko Swinhonis, 20 parts of Radix Scrophulariaes.
CN201410298507.XA 2014-06-19 2014-06-19 A kind of Chinese medicine composition for treating Buerger's disease Expired - Fee Related CN104042788B (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1122243A (en) * 1995-08-16 1996-05-15 岳泰出 Medicinal powder for eliminating embolism and invigorating blood circulation
CN101053632A (en) * 2006-04-13 2007-10-17 吴希文 Traditional Chinese medicine for treating thromboangitis obliterans
CN102908532A (en) * 2012-11-09 2013-02-06 周秀玲 Traditional Chinese medicine for treating thromboangiitis

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1122243A (en) * 1995-08-16 1996-05-15 岳泰出 Medicinal powder for eliminating embolism and invigorating blood circulation
CN101053632A (en) * 2006-04-13 2007-10-17 吴希文 Traditional Chinese medicine for treating thromboangitis obliterans
CN102908532A (en) * 2012-11-09 2013-02-06 周秀玲 Traditional Chinese medicine for treating thromboangiitis

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Inventor after: Yang Zhili

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