CN104041510B - A kind of containing SYP-3375 with the bactericidal composition of triazole bactericidal agent - Google Patents

Abstract

The invention discloses a kind of weight ratio containing SYP-3375 and the agricultural bactericidal composition of Flusilazole and application, SYP-3375 and Flusilazole is 1:30～30:1.Water dispersible granules, wettable powder, suspending agent that this composition can be configured to agriculturally to allow, dispersible oil-suspending agent, missible oil, microemulsion, suspension seed-coating agent, paste formulation.Instant component is reasonable, bactericidal effect is good, drug cost is low, and its activity and and bactericidal effect be not the simple superposition of each composition activity, compared with existing unitary agent, in addition to there is significant bactericidal effect, and have significant synergistic effect, slow down the generation of resistance, preparation less residue, pollution-free to crop, security is good, meeting the security requirement of pesticidal preparations, the present invention has significant prevention effect to apple tree canker, alternaria leaf spot of apple, rice blast, the sheath and culm blight of rice, sigatoka, wheat sharp eyespot.

Description

A kind of containing SYP-3375 with the bactericidal composition of triazole bactericidal agent

Present patent application is that invention and created name is: a kind of sterilization group containing SYP-3375 and triazole bactericidal agent Compound, Application No. 201110205478.4, the divisional application of filing date 2011-07-19 patent application.

Technical field

The present invention relates to a kind of containing SYP-3375 with the agricultural bactericidal composition of triazole bactericidal agent, belong to Recompounded pesticide Technical field.

Background technology

Methoxy acrylic acid series bactericidal agent is bactericide kind the most newly developed, is a big mileage in bactericide field Upright stone tablet.Methoxy acrylic bactericide has the mechanism of action of uniqueness, and it is by pinning the electronics between cytochrome b and c1 Transmit and stop the ATP of cell to synthesize, thus suppress its mitochondrial respiratory and play bacteriostasis.14-demethylation enzyme is pressed down The bacterial strain that preparation, benzamides, dicarboxylic dihydrazides amine and benzimidazole produce resistance is effective.Have protection, treat, root out, Infiltration, systemic activity, and can be in plant, soil and water are quickly degraded.Although this series bactericidal agent mechanism of action is unique, But pathogen produces the speed of resistance the most quickly to it, use cost is high, so limiting methoxy acrylic acid series bactericidal agent Spread uses.

SYP-3375 is a kind of methoxy-methyl acrylate compounds, English common name: coumoxystrobin, chemistry Title: (E)-2-(2-((3-butyl-4-methyl-coumarin-7-base-epoxide) methyl) phenyl)-3-methoxy-methyl acrylate. Have protection and therapeutic action, be the disinfectant use in agriculture of a kind of high-efficiency broad spectrum, to by mastigomycetes, combine bacterium, sac fungus, load The plant disease that bacterium and Fungi Imperfecti cause such as sclerotinia rot of colza, apple tree canker, rice blast, sigatoka, apple Spot defoliations etc. have good preventive effect.

Flusilazole, has another name called gram bacterium star, nova, a lucky star, English common name flusilazole, chemical name: double (4-fluorobenzene Base) methyl (1H-1,2,4-triazol-1-yl methylene supports) silane.Sterol demethylation can be suppressed, to sac fungus, basidiomycetes and half Know that caused by bacterium, disease is effective.Can be used for preventing and treating pear scab and apple mildew, uncinula necator, leaf spot of peanut, cereal white Powder disease and eye spot disease, wheat glume blotch, leaf rust and stripe rust, barley leaf spot etc..

Although SYP-3375 is the disinfectant use in agriculture of a kind of high-efficiency broad spectrum, but it is as methoxy acrylic chemical combination Thing, the mechanism of action is single, Field information is reused germ for a long time and can produce resistance, cause preventive effect to reduce, and use cost High.The triazole pesticides such as above-mentioned hexaconazole, Flusilazole, pathogen produces the speed of resistance the most quickly to it, medication is administered alone Measure increasing, and dosage conference suppression plant growth.If continuous use number of times is more than three times, it is more likely that cause crop Blade diminishes, hardening, become fragile, the poisoning situation such as blackening.Inventor is found by experiment that, by SYP-3375s different for the mechanism of action With triazole bactericidal agent compound, have been surprisingly found that and have significant synergies, can significantly improve treatment, protect prevention effect, Reduce spraying times and dosage, slow down the generation of germ resistance, reduce cost accounting, high to crop safety.

Summary of the invention

It is an object of the invention to provide a kind of component reasonable, synergistic effect is notable, and bactericidal effect is good, and drug cost is low, It is not likely to produce the resistance to the action of a drug, to the agricultural bactericidal composition of crop safety and preparation formulation thereof.

Another object of the present invention is to provide above-mentioned composition prevent and treat apple tree canker, alternaria leaf spot of apple, Application in rice blast, rice sheath blight disease, sigatoka, wheat sharp eyespot.

In order to overcome the defect of existing unitary agent, the technical scheme is that so solution:

A kind of containing SYP-3375 with the agricultural bactericidal composition of triazole bactericidal agent, a combination thereof thing active component is cloves Bacterium ester and Flusilazole, wherein the weight ratio of SYP-3375 and Flusilazole is (1:30)～(30:1), preferably 1:15～15:1, Preferably 1:10～10:1.

The cumulant (content summation) of SYP-3375 and Flusilazole is the 1%～90% of described composition total weight, is preferably 3%～50%, the size of active component cumulant is also closely related with formulation, does not surpasses as the active component cumulant of suspending agent Cross 50%.

The present invention is water-dispersible grain according to the preparation formulation that the method well known to those skilled in the art of the present technique can be prepared Agent, wettable powder, suspending agent, dispersible oil-suspending agent, missible oil, microemulsion, suspension seed-coating agent, paste.

For water dispersible granules, those skilled in the art are very familiar with using corresponding auxiliary agent to complete the present invention.Dispersion Agent is selected from polycarboxylate, lignosulfonates, alkylnaphthalene sulfonate；Wetting agent is selected from alkyl sulfate, alkylsulfonate, naphthalene sulphur Hydrochlorate；Disintegrant is selected from ammonium sulfate, urea, sucrose, glucose；Binding agent is selected from diatomite, cornstarch, PVA, carboxymethyl (ethyl) cellulose family；Filler is selected from diatomite, kaolin, white carbon, fine particle calcium carbonate, talcum powder, attapulgite, potter's clay.

To wettable powder, spendable auxiliary agent has: dispersant is selected from polycarboxylate, lignosulfonates, alkylnaphthalene sulphur Hydrochlorate；Wetting agent is selected from alkyl sulfate, alkylsulfonate, naphthalene sulfonate；Filler is selected from ammonium sulfate, urea, sucrose, grape Sugar, diatomite, kaolin, white carbon, precipitated calcium carbonate, montmorillonite, talcum powder, attapulgite, potter's clay.

To suspending agent, spendable auxiliary agent has: dispersant selected from polycarboxylate, lignosulfonates, alkylnaphthalene sulfonate, Huntsman Corporation of the TERSPERSE 2020(U.S. produces, alkyl naphthalene sulfonic acid salt)；Emulsifying agent is selected from Nongru-700 #(common name: Alkyl phenol formaldehyde resin polyoxyethylene ether), this dish-60#(common name: sorbitan monostearate), Tween-60 #(general Name: sorbitan monostearate APEO), agriculture breast 1601#(common name: phenethyl phenol polyoxyethylene polyoxy third Alkene ether), Huntsman Corporation of the TERSPERSE 4894(U.S. produces)；Wetting agent is selected from alkylphenol-polyethenoxy base ether formaldehyde condensation Thing sulfate, alkylphenol-polyethenoxy base ether phosphate, phenethyl phenol polyethenoxy base ether phosphate, alkyl sulfate, alkyl Sulfonate, naphthalene sulfonate, Huntsman Corporation of the TERSPERSE 2500(U.S. produce)；Thickener selected from xanthans, polyvinyl alcohol, Bentonite, aluminium-magnesium silicate；Preservative is selected from formaldehyde, benzoic acid, Sodium Benzoate；Defoamer such as silicone defoamer；Antifreezing agent Selected from ethylene glycol, propane diols, glycerine, urea, inorganic salts such as sodium chloride.

To microemulsion, spendable auxiliary agent has: emulsifying agent is selected from calcium dodecyl benzene sulfonate (agriculture breast 500#), agriculture breast 700#, agriculture breast 2201#, this dish-60#, Tween-60 #, TX-10, agriculture breast 1601(common name: phenethyl phenol polyoxyethylene polyoxy Propylene ether), agriculture breast 600#, agriculture breast 400#；Assistant for emulsifying agent is selected from methyl alcohol, isopropanol, n-butanol, ethanol；Solvent selected from cyclohexanone, 1-METHYLPYRROLIDONE, dimethylbenzene, toluene, solvent naphtha (trade mark: S-150, S-180, S-200)；Stabilizer is selected from tricresyl phosphite Phenyl ester, epoxychloropropane, stabilizer is selected from triphenyl phosphite, epoxychloropropane；Water is deionized water.

For missible oil, spendable auxiliary agent has: emulsifying agent is selected from calcium dodecyl benzene sulfonate (agriculture breast 500#), agriculture breast 700#, agriculture breast 2201#, this dish-60#, emulsifying agent T-60(common name: sorbitan monostearate APEO), TX- 10(common name: octyl phenol polyoxyethylene (10) ether), agriculture breast 1601#, agriculture breast 600#, agriculture breast 400#；Solvent is selected from dimethylbenzene, molten Agent oil (S-150, S-180, S-200), toluene, biodiesel, methylated vegetable oil；Cosolvent selected from ethyl acetate, methyl alcohol, two NMF, cyclohexanone, acetone, MEK；Stabilizer is selected from triphenyl phosphite, epoxychloropropane, aceticanhydride.

To dispersibling oil-suspending agent, spendable auxiliary agent has: dispersant is selected from polycarboxylate, lignosulfonates, alkyl Naphthalene sulfonate (dispersing agent NNO), TERSPERSE 2020；Emulsifying agent is selected from BY(castor oil polyoxyethylene ether) series emulsifying agent (BY-110, BY-125, BY-140) Nongru-700 #, agriculture breast 2201, this dish-60#, Tween-60 #, agriculture breast 1601#, TERSPERSE 4894；Wetting agent is selected from alkylphenol-polyethenoxy base ether formaldehyde condensation products sulfate, APES phosphate, benzene second Base phenol polyethenoxy base ether phosphate, alkyl sulfate, alkylsulfonate, naphthalene sulfonate, TERSPERSE 2500；Thickener selects From white carbon, polyvinyl alcohol, bentonite, aluminium-magnesium silicate；Antifreezing agent is selected from ethylene glycol, propane diols, glycerine, urea, inorganic salts Such as sodium chloride；Stabilizer is selected from epoxidized soybean oil, epoxychloropropane, triphenyl phosphate；Decentralized medium is selected from soybean oil, vegetable seed Oil, corn oil, methyl oleate, diesel oil, machine oil, mineral oil.

To suspension seed-coating agent, spendable auxiliary agent has: binding agent such as polysaccharide macromolecular compound is (soluble starch, poly- Propylene graft copolymer, xanthan gum, microorganism mucilage), (hydroxypropyl methyl cellulose, carboxymethyl are fine for cellulose derivative Dimension element sodium, ethyl cellulose), seaweeds such as sodium alginate, agar, rosin, paraffin, gelatin, pectin, polyvinyl alcohol, poly-second two Alcohol, polyvinyl acetate, polyacrylamide, polyvinylpyrrolidone and polyhydric alcohol polymer water solubility composite, inorganic bond Agent is selected from aluminium-magnesium silicate, clay, waterglass, gypsum；Dispersant selected from polycarboxylate, lignosulfonates, alkylnaphthalene sulfonate, TERSPERSE 2020；Emulsifying agent selected from Nongru-700 #, agriculture breast 2201, this dish-60#, emulsifying agent T-60, agriculture breast 1601#, TERSPERSE 4894；Wetting agent is selected from alkylphenol-polyethenoxy base ether formaldehyde condensation products sulfate, alkylphenol-polyethenoxy base Ether phosphate, phenethyl phenol polyethenoxy base ether phosphate, alkyl sulfate, alkylsulfonate, naphthalene sulfonate, TERSPERSE 2500；Thickener is selected from xanthans, polyvinyl alcohol, bentonite；Preservative is selected from formaldehyde, benzoic acid, Sodium Benzoate；Defoamer selects From silicone defoamer；Antifreezing agent is selected from ethylene glycol, propane diols, glycerine, urea, inorganic salts such as sodium chloride；Water for go from Sub-water.

To paste, available auxiliary agent has: dispersant is selected from polycarboxylate, alkylnaphthalene sulfonate, lignosulfonates, alkyl Phenol polyethenoxy base ether formaldehyde condensation products phosphate, alkylphenol-polyethenoxy base ether phosphate, phenethyl phenol polyethenoxy base ether Phosphate；Film forming agent is selected from polyacrylamide, acrylic resin, butadiene resin, polyurethane, cellulose nitrate film forming agent；Thickening Agent is in carboxymethylcellulose calcium, aluminium-magnesium silicate, bentonite；Antifreezing agent is selected from ethylene glycol, propane diols；Water is deionized water.

Instant component is reasonable, and treatment adds protective effect, and bactericidal effect is good, reduces times for spraying, and drug cost is low, and its Activity and bactericidal effect are not the simple superposition of each composition activity, but have significant synergistic effect, slow down the generation of resistance, right Crop safety is good, meets the security requirement of pesticidal preparations.The present invention is to apple tree canker, alternaria leaf spot of apple, water Rice rice blast, rice sheath blight disease, sigatoka, wheat sharp eyespot have preferable prevention effect.

Detailed description of the invention

In order to prevent and treat the apple tree canker in agricultural production, inventor has carried out the most multiple with SYP-3375 and Flusilazole The synergy research joined, method particularly includes:

Subjects: apple tree canker (Cytospora mandshurica), the former medicine of test medicine SYP-3375 uses Jilin eight reaches the former medicine that agricultural chemicals Co., Ltd produces, and flusilazole uses Jiangsu Qizhou Green Chemical Co., Ltd, peace The former medicine of the production of units such as Hui Hua star chemical inc.Will by technology department of Shanggezhilu Biosciences Co., Ltd., Shaanxi Former medicine is configured to the test medicine needed, and test method is with reference to " People's Republic of China (PRC) agricultural industry criteria NY/T1156.2- 2006》.First single dose and each Mixed Pharmacy are arranged 5 variable concentrations gradients (on the basis of pilot study result, according to not Different with proportioning with pharmaceutical agent combinations, concentration gradient arranges the most different, and bacteriostasis rate presses geometric progression in the range of 5%～90% Set).The PDA culture medium melted is cooled to 60-70 DEG C, adds quantitative pharmacy by design flow, make containing different doses Toxic culture medium, is repeated 3 times, and after it is sufficiently cool, inoculates the Valsa mali sheet of a diameter of 0.5cm, places incubator Middle cultivation (temperature 25 DEG C ± 1 DEG C), investigates, measures the colony growth diameter of each process respectively, and calculate antibacterial for 5 days Rate, by the linear regression analysis between probit value and the logarithm value of series concentration of inhibiting rate, obtains the EC of each medicament₅₀ Value, Calculate the co-toxicity coefficient (CTC) of mixture by the abundant method of Sun Yun, evaluate the reagent agent activity to germ with this.

The co-toxicity coefficient (CTC) >=120 of complex preparation shows as synergistic effect；CTC≤80 show as antagonism；80 ＜ CTC ＜ 120 shows as summation action.

Table 1 SYP-3375 and the Flusilazole combination Toxicity Determination to apple tree canker

Toxicity Determination result shows: with weight ratio as 1:30～30:1 is mixed to apple tree with Flusilazole for SYP-3375 Rot has preferable virulence, all has significant synergistic effect.

In order to prevent and treat the alternaria leaf spot of apple in agricultural production, inventor has been carried out mutually with SYP-3375 and Flusilazole Compounding synergy research, method particularly includes:

Subjects is Alternaria mali Alternariaalternataf.sp.mali, test method reference " People's Republic of China (PRC) agricultural industry criteria NY/T1156.2-2006 ".First single dose and each Mixed Pharmacy are arranged 5 not (on the basis of pilot study result, different with proportioning according to different agents combination, concentration gradient is arranged also to be had same concentration gradient Institute is different, and bacteriostasis rate is set by geometric progression in the range of 5%～90%).If clear water compares, it is repeated 3 times.Use mycelial growth Performance rate method, by cultured pathogen, aseptically with a diameter of 5 mm card punch, cuts bacterium cake from colony edge, uses Bacterium cake is connected on the culture medium flat plate of different agents concentration by transfer needle, puts cultivation 72h in 26 DEG C of incubators；Check colony diameter, Calculate the percentage of each chemicals treatment suppression mycelial growth, by between probit value and the logarithm value of series concentration of inhibiting rate Linear regression analysis, obtains the EC of each medicament₅₀ Value, calculates the co-toxicity coefficient (CTC) of mixture, evaluates with this by the abundant method of Sun Yun The reagent agent activity to germ.

Table 2 SYP-3375 and the Flusilazole combination Toxicity Determination to apple peels and cores

Toxicity Determination result shows: with weight ratio as 1:30～30:1 is mixed to apple spot with Flusilazole for SYP-3375 Point defoliation has preferable virulence, all has significant synergistic effect.

In order to prevent and treat the rice blast in agricultural production, inventor has carried out the most compounding increasing with SYP-3375 and Flusilazole Effect research, method particularly includes:

Subjects is Pyricularia oryzae (Pyriculariagrisea), and test method is with reference to " People's Republic of China's agriculture Industry professional standard NY/T1156.2-2006 ".First single dose and each Mixed Pharmacy are arranged 5 variable concentrations gradients (in preparation On the basis of result of the test, different with proportioning according to different agents combination, concentration gradient arranges the most different, and bacteriostasis rate is 5% ～set by geometric progression in the range of 90%).If clear water compares, it is repeated 3 times.Use mycelial growth rate method, by cultured Pathogen, aseptically with a diameter of 5 mm card punch, cuts bacterium cake from colony edge, is connected to not by bacterium cake with transfer needle With on the culture medium flat plate of drug concentration, put 27 DEG C, saturated humidity incubator is cultivated；When control group bacterium colony covers with, measure bacterium Fall diameter, calculates the percentage of each chemicals treatment suppression mycelial growth, by probit value and the logarithm of series concentration of inhibiting rate Linear regression analysis between value, obtains the EC of each medicament₅₀ Value, calculates the co-toxicity coefficient (CTC) of mixture by the abundant method of Sun Yun, with This evaluates the reagent agent activity to germ.

Table 3 SYP-3375 and the Flusilazole combination Toxicity Determination to Pyricularia oryzae

Toxicity Determination result shows: with weight ratio as 1:30～30:1 is mixed to rice blast with Flusilazole for SYP-3375 Bacterium has preferable virulence, all has significant synergistic effect.

In order to prevent and treat the rice sheath blight disease in agricultural production, inventor has carried out the most compounding with SYP-3375 and Flusilazole Synergy research, method particularly includes:

Subjects is Rhizoctonia solani Kuhn (Rhizoctonia solani), and test method is with reference to " China's people's republicanism State agricultural industry criteria NY/T1156.2-2006 ".First single dose and each Mixed Pharmacy are arranged 5 variable concentrations gradients ( On the basis of pilot study result, different with proportioning according to different agents combination, concentration gradient arranges the most different, bacteriostasis rate Set by geometric progression in the range of 5%～90%).If clear water compares, it is repeated 3 times.Use mycelial growth rate method, will cultivate Good pathogen, aseptically with a diameter of 5 mm card punch, cuts bacterium cake from colony edge, is connect by bacterium cake with transfer needle On the culture medium flat plate of different agents concentration, put 27 DEG C, saturated humidity incubator is cultivated；When control group bacterium colony covers with, survey Amount colony diameter, calculates the percentage of each chemicals treatment suppression mycelial growth, by the probit value of inhibiting rate and series concentration Linear regression analysis between logarithm value, obtains the EC of each medicament₅₀ Value, calculates the co-toxicity coefficient of mixture by the abundant method of Sun Yun (CTC), the reagent agent activity to germ is evaluated with this.

Table 4 SYP-3375 and the Flusilazole combination Toxicity Determination to Rhizoctonia solani Kuhn

Toxicity Determination result shows: with weight ratio as 1:30～30:1 is mixed to paddy rice line with Flusilazole for SYP-3375 Rot bacterium has preferable virulence, all has significant synergistic effect.

In order to prevent and treat the wheat sharp eyespot in agricultural production, inventor has carried out the most compounding with SYP-3375 and Flusilazole Synergy research, method particularly includes:

Subjects is to cause the Rhizoctonia cerealis of wheat sharp eyespot (Rhizoctonia cere-alis), test method With reference to " People's Republic of China (PRC) agricultural industry criteria NY/T1156.2-2006 ".First single dose and each Mixed Pharmacy are arranged 5 (on the basis of pilot study result, different with proportioning according to different agents combination, concentration gradient is also arranged variable concentrations gradient Different, bacteriostasis rate is set by geometric progression in the range of 5%～90%).If clear water compares, it is repeated 3 times.Use mycelia raw Long performance rate method, by cultured pathogen, aseptically with a diameter of 5 mm card punch, cuts bacterium cake from colony edge, With transfer needle, bacterium cake is connected on the culture medium flat plate of different agents concentration, puts 27 DEG C, saturated humidity incubator is cultivated；Wait to compare When group bacterium colony covers with, measure colony diameter, calculate the percentage of each chemicals treatment suppression mycelial growth, by the probability of inhibiting rate Linear regression analysis between value and the logarithm value of series concentration, obtains the EC of each medicament₅₀ Value, calculates mixture by the abundant method of Sun Yun Co-toxicity coefficient (CTC), evaluate the reagent agent activity to germ with this.

Table 5 SYP-3375 and the Flusilazole combination Toxicity Determination to Rhizoctonia cerealis

Toxicity Determination result shows: with weight ratio as 1:30～30:1 is mixed to cereal silk with Flusilazole for SYP-3375 Pyrenomycetes has preferable virulence, all has significant synergistic effect.

In order to prevent and treat the sigatoka in agricultural production, inventor has carried out the most compounding with SYP-3375 and Flusilazole Synergy research, method particularly includes:

Subjects is that in sigatoka (Sigatokadiseaseofbanana), generation is the most universal, harm is the most serious Cercospora leaf spot (Cercosproa musae).The former medicine of test medicine SYP-3375 uses Jilin eight to reach agricultural chemicals Co., Ltd The former medicine produced, flusilazole uses Jiangsu Qizhou Green Chemical Co., Ltd, the Anhui China star limited public affairs of chemical industry share The former medicine of the production of units such as department.By technology department of Shanggezhilu Biosciences Co., Ltd., Shaanxi, former medicine is configured to the test needed Medicament.First single dose and each Mixed Pharmacy are arranged 5 variable concentrations gradients (on the basis of pilot study result, according to not Different with proportioning with pharmaceutical agent combinations, concentration gradient arranges the most different, and bacteriostasis rate presses geometric progression in the range of 5%～90% Set).If clear water compares, it is repeated 3 times.The middle part any of several broadleaf plants selecting initial morbidity at Long Sheng town, Guangdong Kaiping City morbidity Jiao Yuan in 2010 Leaf, marks, by ink pens, the scab (about 5.0 mm × 1.0 mm) being newly formed and tests, 50 diseases of each repeating label Spot, uniformly sprays the positive and negative at mark any of several broadleaf plants leaf by each treatment agent.Within 10 days, investigate respectively and record disease before spray medicine and after spray medicine Spot length, calculates scab length increment and fungistatic effect, the fungistatic effect of different disposal is carried out regression analysis, and calculates EC₅₀Value.Calculate the co-toxicity coefficient (CTC) of mixture by the abundant method of Sun Yun, evaluate the reagent agent activity to germ with this.

Table 6 SYP-3375 and the Flusilazole combination toxicity test to Cercospora musae bacterium leaf spot

Toxicity Determination result shows: with weight ratio as 1:30～30:1 is mixed to banana tail with Flusilazole for SYP-3375 Spore bacterium leaf spot has preferable virulence, all has significant synergistic effect.

Below in conjunction with embodiment, present invention is described further.

Embodiment 1

Weigh 10% SYP-3375,20% Flusilazole, 3% TERSPERSE 2700,3% dispersing agent NNO, 2% pull open powder BX, 1%K-12,1% carboxymethylcellulose calcium, 3% urea, diatomite add to 100% weight portion.Above-mentioned raw materials frequent regulation water intaking point The method of shot agent i.e. mixes, ultra micro air-flow crushing, mixing, granulation step produce 30% SYP-3375 Flusilazole water-dispersible grain Agent.

This formula is used for preventing and treating apple peels and cores, and by 5000 times of dilute with water sprayings, after medicine, the preventive effect of 15 days is 91.1%.20% SYP-3375 suspending agent presses 4000 times by 2000 times and 40% Flusilazole, uses by same method, after medicine The preventive effect of 15 days is 78.5% and 76.4% respectively.

Embodiment 2

Weigh 20% SYP-3375,30% Flusilazole, 4% calcium lignosulfonate, 3% TERSPERSE 2700,2% pull open Powder BX, 2%K-12,3% White Carbon black, fine particle calcium carbonate add to 100% weight portion.Above-mentioned raw materials is blended, prepares 50% fourth after air-flow crushing Fragrant bacterium ester Flusilazole wettable powder.

This formula is used for preventing and treating alternaria leaf spot of apple, and by 6000 times of dilute with water sprayings, after medicine, the preventive effect of 14 days is 89.6%.20% SYP-3375 suspending agent presses 4000 times by 2000 times and 40% Flusilazole, uses by same method, after medicine The preventive effect of 14 days is for 79.2% and 78.2% respectively.

Embodiment 3

Weigh 5% SYP-3375,35% Flusilazole, 5%TERSPERSE 4894,2%TERSPERSE 2500,3% TERSPERSE 2020,0.2% xanthans, 5% propane diols, 0.5% benzoic acid, 1% epoxychloropropane, 0.5% organic silicon defoamer, 1% epoxychloropropane, deionized water add to 100% weight portion.Above-mentioned raw materials is blended, high speed shear dispersion 30min, uses sand milling The SYP-3375 Flusilazole suspending agent of 40% is prepared after machine sand milling.

This formula is used for preventing and treating rice blast, and mu consumption is 10g, and with water 50kg dilution spraying, after medicine, the preventive effect of 10 days is 88.5%.20% SYP-3375 suspending agent mu consumption is 22.5g and 40% Flusilazole mu consumption is 12g, makes by same method With, after medicine, the preventive effect of 10 days is for 80.3% and 81.6% respectively.

Embodiment 4

Weigh 2.5% SYP-3375,7.5% Flusilazole, 4% Nongru-700 #, 3% agriculture breast 500#, 6% agriculture breast 600#, 10% diformazan Benzene, 5% cyclohexanone, 5% isopropanol, 1% epoxychloropropane, through dissolving completely and mixing, deionized water adds to 100% weight Part, prepare 10% SYP-3375 oxazole fluosilicate micro emulsion after stirring.

This formula is used for preventing and treating sigatoka, and by 1500 times of dilute with water sprayings, after medicine, the preventive effect of 10 days is 91.6%. 20% SYP-3375 suspending agent by 2000 times and 10% Flusilazole by 1000 times, with same method use, after medicine 10 days Preventive effect is for 75.7% and 81.3% respectively.

Embodiment 5

Weigh 10% SYP-3375,15% Flusilazole, 4% agriculture breast 500#, 2% agriculture breast 600#, 3% agriculture breast 2201#, 10% dimethyl Formamide, solvent naphtha S-180 add to 100% weight portion.Above-mentioned raw materials is blended, and stirring and dissolving prepares 25% cloves bacterium the most afterwards Ester Flusilazole.

This formula is used for preventing and treating wheat sharp eyespot, and mu consumption is 20g, by water 50kg dilution spraying, the preventive effect of 10 days after medicine It is 90.5%.20% SYP-3375 suspending agent mu consumption is 22.5g and 40% Flusilazole mu consumption is 12g, by same method Using, after medicine, the preventive effect of 10 days is for 79.3% and 71.2% respectively.

Embodiment 6

Weigh 7.5% SYP-3375,7.5% Flusilazole, 2% dispersing agent NNO, 3% agriculture breast 2201#, 10% BY-110,1% TERSPERSE 2500,1% aluminium-magnesium silicate, 3% glycerine, 15% epoxidized soybean oil, soybean oil add to 100% weight portion.Above-mentioned raw materials Blended, high speed shear dispersion 30min, dispersible oil-suspending agent with preparing 15% SYP-3375 Flusilazole after sand mill sand milling.

This formula is used for preventing and treating sigatoka, and by 2000 times of dilute with water sprayings, after medicine, the preventive effect of 10 days is 92.3%. 20% SYP-3375 suspending agent by 2000 times and 10% Flusilazole by 1000 times, with same method use, after medicine 10 days Preventive effect is for 76.7% and 83.2% respectively.

Embodiment 7

Weigh 0.3% SYP-3375,0.7% Flusilazole, 4% alkylnaphthalene sulfonate, 7% butadiene resin, 5% bentonite, 2% the third Glycol, deionized water add to 100% weight portion.Above-mentioned raw materials is blended, with preparing 1% SYP-3375 fluorine silicon after sand mill sand milling Azoles paste.

This formula is used for preventing and treating apple tree canker, wipes off spring at scab after bark, dilutes 3 times and smears scab, autumn Check that preventive effect is 97.8%.20% SYP-3375 suspending agent smears scab by 150 times and 40% Flusilazole by after 300 times of dilutions, Check that preventive effect is for 87.8% and 65.2% respectively autumn.

From above example, SYP-3375 is compounding with Flusilazole combination, can be made into water dispersible granules, wettable powder Agent, suspending agent, dispersible oil-suspending agent, missible oil, microemulsion, suspension seed-coating agent, paste formulation, to apple tree canker, apple Spot defoliation, rice blast, the sheath and culm blight of rice, sigatoka, wheat sharp eyespot have significant prevention effect, and dosage is few, anti- Control effect advantages of higher, save drug cost and dosage, and good to crop safety, therefore produce to have and widely should Use prospect.

In sum, the composition of the present invention is to use two kinds of active component compound schemes, and its activity and bactericidal effect are not It is the simple superposition of each composition activity, compared with existing unitary agent, in addition to there is significant bactericidal effect, and has notable Synergistic effect, slow down the generation of resistance, preparation less residue, pollution-free to crop, security is good, meets the peace of pesticidal preparations Full property requirement.

Claims (7)

1. one kind contains SYP-3375 and the agricultural bactericidal composition of triazole bactericidal agent, it is characterised in that composition active component For SYP-3375 and Flusilazole, wherein the weight ratio of SYP-3375 and Flusilazole is (1:30)～(30:1).

The most according to claim 1 containing SYP-3375 with the agricultural bactericidal composition of triazole bactericidal agent, its feature exists In: the weight ratio of SYP-3375 and Flusilazole is (1:15)～(15:1).

The most according to claim 2 containing SYP-3375 with the agricultural bactericidal composition of triazole bactericidal agent, its feature exists In: the weight ratio of SYP-3375 and Flusilazole is (1:10)～(10:1).

4. one of arbitrarily described containing SYP-3375 and the agricultural bactericidal composition of triazole bactericidal agent according to claims 1 to 3, It is characterized in that: the cumulant of SYP-3375 and Flusilazole is the 1%～90% of described composition total weight.

Contain the agricultural bactericidal composition of SYP-3375 and triazole bactericidal agent the most according to claim 4, it is characterised in that: The cumulant of SYP-3375 and Flusilazole is the 3%～50% of described composition total weight.

Contain the agricultural bactericidal composition of SYP-3375 and triazole bactericidal agent the most according to claim 1, it is characterised in that Described combination dosage form is water dispersible granules, wettable powder, suspending agent, missible oil, microemulsion, paste.

7. the bactericidal composition containing SYP-3375 and triazole bactericidal agent described in claim 1 is preventing and treating apple tree canker, apple The really application in spot defoliation, rice blast, rice sheath blight disease, sigatoka, wheat sharp eyespot.