CN104031823A - Cell detection chip and adapter thereof - Google Patents

Cell detection chip and adapter thereof Download PDF

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Publication number
CN104031823A
CN104031823A CN201410305151.8A CN201410305151A CN104031823A CN 104031823 A CN104031823 A CN 104031823A CN 201410305151 A CN201410305151 A CN 201410305151A CN 104031823 A CN104031823 A CN 104031823A
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CN
China
Prior art keywords
chip
cell detection
substrate
circuit card
detection
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CN201410305151.8A
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Chinese (zh)
Other versions
CN104031823B (en
Inventor
吴旭东
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Jiangsu Tall And Erect Microorganism Science And Technology Ltd
Original Assignee
Jiangsu Tall And Erect Microorganism Science And Technology Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Jiangsu Tall And Erect Microorganism Science And Technology Ltd filed Critical Jiangsu Tall And Erect Microorganism Science And Technology Ltd
Priority to CN201410305151.8A priority Critical patent/CN104031823B/en
Publication of CN104031823A publication Critical patent/CN104031823A/en
Application granted granted Critical
Publication of CN104031823B publication Critical patent/CN104031823B/en
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Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/04Exchange or ejection of cartridges, containers or reservoirs
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/10Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept

Abstract

The invention relates to a cell detection chip and an adapter thereof. The cell detection chip comprises a substrate and a chip part, wherein the chip part has a sheet body which is provided with collecting holes; the substrate and the chip part are opposite, a detection channel is arranged between the substrate and the chip, and a fluid to be detected flows in the detection channel and collects signals. The adapter comprises a circuit board and a shell, wherein an installation groove is formed in the shell, a plurality of contact pins are arranged on the surface, opposite to the chip, of the circuit board, and the chip is provided with the collecting holes which are in one-to-one correspondence to the positions of part or all of the contact pins; after the circuit board and the chip are installed, the contact pins penetrate through the collecting holes. The cell detection chip is applicable to analysis and detection of any cell or particle; the circuit board and the chip are separated, so that the chip only needs to be replaced in each detection process, so that the detection cost for once is greatly lowered. The whole operation is very simple and needs no professionals, and the equipment is small in size and can be used in various mobile or non-mobile application conditions.

Description

Cell detection chip and adapter thereof
Technical field
The present invention relates to medical detection field, particularly a kind of cell detection chip and adapter thereof.
Background technology
Now, all routine blood test detection techniques are all main equipment or the bench devices based on drain cell art, also do not have to occur can be commercial minicell test set.
Summary of the invention
The technical problem to be solved in the present invention is: in order to solve the deficiency of existing cell detection equipment, the invention provides a kind of cell detection chip and adapter thereof.
The technical solution adopted for the present invention to solve the technical problems is: a kind of cell detection chip, comprise substrate and chip section, and described chip section has flake main body, offers and gather hole in described main body; Substrate and chip section be oppositely arranged and between there is sense channel.
Described chip section and substrate are adhesively fixed.
Described substrate is plastic sheet, sheet glass, quartz plate or silicon chip.
The main body of described chip section is plastic sheet, sheet glass, quartz plate or silicon chip.
A kind of cell detection adaptor chip for cell detection chip of the present invention, comprise circuit card and shell, in described shell, be provided with mounting groove, described substrate, chip and circuit card are successively set in the mounting groove of described shell from bottom to up, the one side that described circuit card is relative with chip is provided with many contact pilotages, offers the collection hole matching one by one with part or all of described stylus position on described chip; After described circuit card and chip are installed, described contact pilotage is located in described collection hole.
The invention has the beneficial effects as follows, cell detection chip of the present invention and adapter thereof, because circuit card is separated with chip, and the consumptive material of circuit card non-once, a circuit card can meet the detection of thousands of times, each testing process only need to be changed chip, chip is medical disposable material, and tooling cost is lower, greatly reduces the testing cost of single, chip is recycled as plastic prod is convenient, has good environment-friendly advantage.Whole operation is very simple, without the need for professional and technical personnel, and device miniaturization, can under various movements or non-moving application conditions, use.
Accompanying drawing explanation
Below in conjunction with drawings and Examples, the present invention is further described.
Fig. 1 is the structural representation of the optimum embodiment of cell detection chip of the present invention.
Fig. 2 is the structural representation of the optimum embodiment of cell detection adaptor chip of the present invention.
Fig. 3 is the exploded perspective view that cell detection chip of the present invention and adapter are installed.
Fig. 4 is the structural representation of cell detection adaptor chip housing of the present invention.
Fig. 5 is the structural representation of circuit card and chip assembling in cell detection adaptor chip of the present invention.
Fig. 6 is the structural representation of circuit card and chip assembling in cell detection adaptor chip of the present invention.
In figure 1, substrate, 2, chip, 21, gather hole, 3, circuit card, 31, contact pilotage, 32, contact, 33, unfilled corner shape, 4, shell, 41, mounting groove, 411, hypotenuse, 412, construction opening, 42, step, 43, groove, 44, through hole.
Embodiment
In conjunction with the accompanying drawings, the present invention is further detailed explanation.These accompanying drawings are the schematic diagram of simplification, basic structure of the present invention is only described in a schematic way, so it only show the formation relevant with the present invention.
As shown in Figure 1, a kind of cell detection chip of the present invention, comprises substrate 1 and chip section 2, and chip section 2 has flake main body, offers and gather hole 21 in main body, and the main body of described substrate 1 and chip section 2 is plastic sheet or sheet glass.Substrate 1 is oppositely arranged and is adhesively fixed with chip section 2.
As shown in Fig. 2~6, a kind of cell detection adaptor chip of the present invention, comprise circuit card 3 and shell 4, in described shell 4, be provided with mounting groove 41, described substrate 1, chip 2 and circuit card 3 are successively set in the mounting groove 41 of described shell 4 from bottom to up, the one side that described circuit card 3 is relative with chip 2 is provided with 6 contact pilotages 31, offers 6 collection holes 21 that match one by one with described 6 contact pilotage 31 positions on described chip 2; After described circuit card 3 is installed with chip 2, described contact pilotage 31 is located in described collection hole 21; Described circuit card 3 is provided with away from the one side of chip 26 contacts 32 that are connected with late-class circuit, described 6 contacts 32 respectively with 6 contact pilotage 31 connections, contact 32 is arranged side by side in one end of circuit card 3 edge.Described substrate 1 and the bonding compositing chip of chip 2, have sense channel between substrate 1 and chip section 2, fluid to be detected sense channel in flow and realize signals collecting.Only need splash into and detect sample in sense channel, then circuit card 3 is placed in mounting groove 41, just can carry out rapid detection.
As shown in Figure 3, described shell 4 upper openings, bottom is mounting groove 41, and described mounting groove 41 has construction opening 412, and described construction opening 412 places have step 42; Described shell 4 wherein on two relative sides, all offer groove 43; Described shell 4 bottoms also offer through hole 44.
On the mounting groove 41 of described circuit card 3 and shell 4, be equipped with fool proof unit, the fool proof unit of described circuit card 3 is that 3 one jiaos of outer side edges of circuit card form unfilled corner shape 33, and the fool proof unit on described mounting groove 41 is hypotenuse 411 corresponding with described unfilled corner shape 33 on the inner side edge of mounting groove 41.
The above-mentioned foundation desirable embodiment of the present invention of take is enlightenment, and by above-mentioned description, relevant staff can, within not departing from the scope of this invention technological thought, carry out various change and modification completely.The technical scope of this invention is not limited to the content on specification sheets, must determine its technical scope according to claim scope.

Claims (5)

1. a cell detection chip, is characterized in that: comprise substrate (1) and chip section (2), described chip section (2) has flake main body, offers and gather hole (21) in described main body; Substrate (1) and chip section (2) be oppositely arranged and between there is sense channel.
2. cell detection chip as claimed in claim 1, is characterized in that: described chip section (2) is adhesively fixed with substrate (1).
3. cell detection chip as claimed in claim 1, is characterized in that: described substrate (1) is plastic sheet, sheet glass, quartz plate or silicon chip.
4. the cell detection chip as described in any one in claim 1-3, is characterized in that: the main body of described chip section (2) is plastic sheet, sheet glass, quartz plate or silicon chip.
5. the cell detection adaptor chip for the cell detection chip as described in claim 1-4 any one, it is characterized in that: comprise circuit card (3) and shell (4), in described shell (4), be provided with mounting groove (41), described substrate (1), chip (2) and circuit card (3) are successively set in the mounting groove (41) of described shell (4) from bottom to up, the one side that described circuit card (3) is relative with chip (2) is provided with many contact pilotages (31), on described chip (2), offer the collection hole (21) matching one by one with part or all of described contact pilotage (31) position, after described circuit card (3) is installed with chip (2), described contact pilotage (31) is located in described collection hole (21).
CN201410305151.8A 2014-06-27 2014-06-27 cell detection chip and adapter thereof Active CN104031823B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201410305151.8A CN104031823B (en) 2014-06-27 2014-06-27 cell detection chip and adapter thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201410305151.8A CN104031823B (en) 2014-06-27 2014-06-27 cell detection chip and adapter thereof

Publications (2)

Publication Number Publication Date
CN104031823A true CN104031823A (en) 2014-09-10
CN104031823B CN104031823B (en) 2016-08-24

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Application Number Title Priority Date Filing Date
CN201410305151.8A Active CN104031823B (en) 2014-06-27 2014-06-27 cell detection chip and adapter thereof

Country Status (1)

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CN (1) CN104031823B (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105758782A (en) * 2014-12-19 2016-07-13 江苏卓微生物科技有限公司 Portable rapid particle detection apparatus and working method thereof
CN106198363A (en) * 2016-09-13 2016-12-07 江苏卓微生物科技有限公司 A kind of FCM analysis chip

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN2611382Y (en) * 2003-01-29 2004-04-14 陕西西大北美基因股份有限公司 Diagnosis type cell chip for pathogenic microorganism infection
CN1714294A (en) * 2002-12-20 2005-12-28 德商·Atg测试系统股份有限公司 Adapter for testing conductor arrangements
CN103611584A (en) * 2013-10-29 2014-03-05 武汉斯坦姆赛尔生物技术有限公司 Micro-fluidic chip and micro-fluidic chip based cell counting method
CN203960191U (en) * 2014-06-27 2014-11-26 江苏卓微生物科技有限公司 cell detection chip and adapter thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1714294A (en) * 2002-12-20 2005-12-28 德商·Atg测试系统股份有限公司 Adapter for testing conductor arrangements
CN2611382Y (en) * 2003-01-29 2004-04-14 陕西西大北美基因股份有限公司 Diagnosis type cell chip for pathogenic microorganism infection
CN103611584A (en) * 2013-10-29 2014-03-05 武汉斯坦姆赛尔生物技术有限公司 Micro-fluidic chip and micro-fluidic chip based cell counting method
CN203960191U (en) * 2014-06-27 2014-11-26 江苏卓微生物科技有限公司 cell detection chip and adapter thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105758782A (en) * 2014-12-19 2016-07-13 江苏卓微生物科技有限公司 Portable rapid particle detection apparatus and working method thereof
CN106198363A (en) * 2016-09-13 2016-12-07 江苏卓微生物科技有限公司 A kind of FCM analysis chip

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Publication number Publication date
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