CN104017667A - Antibacterial cleaning solution for instruments - Google Patents
Antibacterial cleaning solution for instruments Download PDFInfo
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- CN104017667A CN104017667A CN201410289773.6A CN201410289773A CN104017667A CN 104017667 A CN104017667 A CN 104017667A CN 201410289773 A CN201410289773 A CN 201410289773A CN 104017667 A CN104017667 A CN 104017667A
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Abstract
The invention discloses an antibacterial cleaning solution for instruments. The antibacterial cleaning solution per litre is characterized by containing 0.8-1.2 g of sodium hydroxide, 1.0-2.0 g of alkali metal hydroxide, 0.01-0.06 percent by volume of quaternary cationic surface active agent, 0.05-0.2 percent by volume of non-ionic surface active agent, and 0.1-1.8 percent by volume of foam inhibitor. The cleaning solution disclosed by the invention has the advantages of being cheap in price and low in cost, and effectively removing residues such as fibrin, crystals, oil, dyes and latex particles which are easily adhered to a colorimetric cup, thereby effectively cleaning the colorimetric cup and ensuring the accuracy of detection results.
Description
Technical field
The present invention relates to a kind of antibacterial cleaning solution of instrument.
Background technology
Cellanalyzer, taking its high accuracy, high degree of accuracy, high flexibility and high efficiency as feature, is being born a large amount of work in clinical labororatory, is one of instrument of being most widely used of current clinical labororatory.In clinical labororatory, need on the one hand the project of detection many, the corresponding external diagnosis reagent complicated using, specimen types is various on the other hand, there are serum, blood plasma, urine, ascites pleural fluid, cerebrospinal fluid etc., therefore, cuvette, pipeline etc. are just likely by pollutions such as scleroproein, crystallization, grease, dyestuffs, breed bacteria, cannot ensure the plot of instrument, as can be seen here, cleaning performance can directly affect the accuracy of detected result, in order to obtain reliable detected result, it is particularly important that the cleaning system of full automatic biochemical apparatus shows.
The cellanalyzer of domestic use, its reaction cup great majority belong to discrete water bath with thermostatic control, and the hatching tank and generally need to use scavenging solution routine cleaning of this kind of cellanalyzer, to keep it clean, prevent bacterial growth, and reaction cup need to regularly be soaked with scavenging solution.
Antibacterial cleaning solution is wherein mainly used in the strengthening cleaning of cuvette and the cleaning of reaction incubation slot.
The antibacterial cleaning solution source that clinical labororatory is used is at present mainly dependence on import, but import reagent cost is higher, testing cost is increased, so its widespread use is restricted, also having is on the one hand domestic antibacterial cleaning solution, but practical effect is not good enough, particularly for latex enhancing immune than the test item of turbid transmission method (PETIA Latex-enhanced immunoturbidimetric assay), because the latex containing in reagent is a kind of high molecular polymer, its major ingredient is polystyrene, it is easy to adhere on cuvette, particularly polypropylene material cuvette, situation severe patient, form one deck oyster white bur at the internal surface of cuvette, these oyster white burs can affect the light transmission of cuvette, and then affect absorbance reading, finally cause detected result inaccurate.
Summary of the invention
Goal of the invention: the present invention is directed to the deficiencies in the prior art, a kind of low price is proposed, cost is low, and can effectively remove scleroproein, crystallization, grease, dyestuff, latex particle etc. and be easy to adhere to residue on cuvette, thereby effectively clean cuvette, ensure the cellanalyzer antibacterial cleaning solution of, the good stability low for cost of detected result accuracy.
Technical scheme: one of the present invention is for cellanalyzer antibacterial cleaning solution, in every 1L antibacterial cleaning solution, contain: in every 1L antibacterial cleaning solution (water is settled to 1L), contain: the sodium hydroxide of 0.8～1.2g, the alkali metal hydroxide of 1.0～2.0g, volume is very than the quaternary cationics that is 0.01～0.06%, volume is very than the nonionogenic tenside that is 0.05～0.2%, and volume is very than the suds suppressor that is 0.1～1.8%.
The above-mentioned content for the each composition of antibacterial cleaning solution is: in every 1L antibacterial cleaning solution, contain: the sodium hydroxide of 0.85g, 1.35g alkali metal hydroxide, volume is very than the quaternary cationics that is 0.05%, volume is very than the nonionogenic tenside that is 0.125%, and volume is very than the suds suppressor that is 1%.
Other inorganic salt such as sodium hydroxide available hydrogen potassium oxide of the present invention replace; Described alkali metal hydroxide is water glass or sodium carbonate; Described quaternary cationics is that polyoxyethylene glycol is to iso-octyl phenyl ether (Triton X – 100 or title Triton X-100) or polyoxyethylene sorbitan monooleate (Tween-80); Described nonionogenic tenside is that bromine alkyl dimethyl is for benzene methanamine (bromogeramine or dodecyl dimethyl benzyl ammonium bromide) or dodecyl dimethyl phenoxy group brometo de amonio (domiphen bromide or dodecyl-dimethyl-2-phenoxy group-ethyl brometo de amonio) or tetradecyl lutidine brometo de amonio (Myristylpicolinii Bromide); Described suds suppressor is Virahol.From above technical scheme, in cellanalyzer antibacterial cleaning solution provided by the invention, except containing sodium hydroxide, also contain alkali metal hydroxide, quaternary cationics, nonionogenic tenside and suds suppressor.Wherein, alkali metal hydroxide plays the effect of a washing assistant in antibacterial cleaning solution, and cost is low, and in alkali metal hydroxide washing assistant, alkaline alkali metal oxyhydroxide is better to the effect of enhancing tensio-active agent decontamination.Quaternary cationics has very strong surface-active action, plays in the present invention the effect of clean a, emulsification.Nonionogenic tenside, has the character of acid-fast alkali-proof, de-sludging, has germicidal action simultaneously, and it has very strong adsorption at bacterium surface, thereby stops breathing and the sugared solution effect of bacterium, impels protein denaturation, plays the effect of sterilization.Suds suppressor preferably adopts Virahol, can effectively eliminate the bubble producing when reaction cup is rotated.
Beneficial effect: scavenging solution of the present invention is for the cleaning of cellanalyzer, cleaning performance is good, cost is low, and (raw material is commercial product, be easy to get, cheaply), good stability, low residue, detected result is accurate and precision good, especially can solve high molecular polymer in PETIA method of testing and adhere to cuvette and form the problem of oyster white bur.Scavenging solution of the present invention not only cost is low, good stability, and there is the advantage such as low residue and low crossed contamination.
Embodiment
Below in conjunction with specific embodiment, the invention will be further described:
Embodiment 1
A kind of antibacterial cleaning solution of instrument, in every 1L antibacterial cleaning solution, contain: the sodium hydroxide of 0.8～1.2g, the alkali metal hydroxide of 1.0～2.0g, volume percent is 0.01～0.06% quaternary cationics, volume percent is 0.05～0.2% nonionogenic tenside, the suds suppressor that volume percent is 0.1～1.8%.
Claims (5)
1. the antibacterial cleaning solution of an instrument, it is characterized in that: in every 1L antibacterial cleaning solution, contain: the sodium hydroxide of 0.8～1.2g, the alkali metal hydroxide of 1.0～2.0g, volume percent is 0.01～0.06% quaternary cationics, volume percent is 0.05～0.2% nonionogenic tenside, the suds suppressor that volume percent is 0.1～1.8%.
2. according to the antibacterial cleaning solution of a kind of instrument described in claim 1, it is characterized in that: in every 1L antibacterial cleaning solution, contain: the sodium hydroxide of 0.85g, 1.35g alkali metal hydroxide, volume percent is 0.05% quaternary cationics, volume percent is 0.125% nonionogenic tenside, the suds suppressor that volume percent is 1%.
3. according to the antibacterial cleaning solution of a kind of instrument described in claim 1, it is characterized in that the inorganic salt such as described sodium hydroxide available hydrogen potassium oxide replace.
4. according to the antibacterial cleaning solution of a kind of instrument described in claim 1, it is characterized in that described alkali metal hydroxide is water glass or sodium carbonate.
5. according to the antibacterial cleaning solution of a kind of instrument described in claim 1, it is characterized in that described quaternary cationics is that polyoxyethylene glycol is to iso-octyl phenyl ether or polyoxyethylene sorbitan monooleate; Described nonionogenic tenside is dodecyl dimethyl benzyl ammonium bromide or dodecyl dimethyl phenoxy group brometo de amonio or tetradecyl lutidine brometo de amonio; Described suds suppressor is Virahol.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410289773.6A CN104017667A (en) | 2014-06-25 | 2014-06-25 | Antibacterial cleaning solution for instruments |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410289773.6A CN104017667A (en) | 2014-06-25 | 2014-06-25 | Antibacterial cleaning solution for instruments |
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| CN104017667A true CN104017667A (en) | 2014-09-03 |
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| CN201410289773.6A Pending CN104017667A (en) | 2014-06-25 | 2014-06-25 | Antibacterial cleaning solution for instruments |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105441225A (en) * | 2015-12-18 | 2016-03-30 | 杭州毕肯莱博生物科技有限公司 | Biological instrument pipeline cleaning liquid and preparation method thereof |
| CN106753876A (en) * | 2015-11-23 | 2017-05-31 | 迈瑞南京生物技术有限公司 | Bottle-washing agent |
| CN107365639A (en) * | 2017-03-31 | 2017-11-21 | 上海艾瑞德生物科技有限公司 | A kind of collaurum platform cleaning fluid |
| CN108085195A (en) * | 2017-12-19 | 2018-05-29 | 山东联星能源集团有限公司 | A kind of ultrafiltration cleaning agent and application method for military precision equipment of high efficiency high quality |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6013615A (en) * | 1995-07-26 | 2000-01-11 | The Clorox Company | Antimicrobial hard surface cleaner |
| CN102304439A (en) * | 2011-08-08 | 2012-01-04 | 宁波美康盛德生物科技有限公司 | Antibacterial cleaning solution for full-automatic biochemistry analyzer |
-
2014
- 2014-06-25 CN CN201410289773.6A patent/CN104017667A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6013615A (en) * | 1995-07-26 | 2000-01-11 | The Clorox Company | Antimicrobial hard surface cleaner |
| CN102304439A (en) * | 2011-08-08 | 2012-01-04 | 宁波美康盛德生物科技有限公司 | Antibacterial cleaning solution for full-automatic biochemistry analyzer |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106753876A (en) * | 2015-11-23 | 2017-05-31 | 迈瑞南京生物技术有限公司 | Bottle-washing agent |
| CN105441225A (en) * | 2015-12-18 | 2016-03-30 | 杭州毕肯莱博生物科技有限公司 | Biological instrument pipeline cleaning liquid and preparation method thereof |
| CN107365639A (en) * | 2017-03-31 | 2017-11-21 | 上海艾瑞德生物科技有限公司 | A kind of collaurum platform cleaning fluid |
| CN107365639B (en) * | 2017-03-31 | 2020-04-24 | 上海艾瑞德生物科技有限公司 | Colloidal gold platform cleaning solution |
| CN108085195A (en) * | 2017-12-19 | 2018-05-29 | 山东联星能源集团有限公司 | A kind of ultrafiltration cleaning agent and application method for military precision equipment of high efficiency high quality |
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Application publication date: 20140903 |