CN103992982A - 骨髓细胞用于长期培养胰腺胰岛细胞的用途 - Google Patents
骨髓细胞用于长期培养胰腺胰岛细胞的用途 Download PDFInfo
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0676—Pancreatic cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
- C12N2502/1394—Bone marrow stromal cells; whole marrow
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
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- Chemical Kinetics & Catalysis (AREA)
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- Pharmacology & Pharmacy (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Endocrinology (AREA)
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- Hematology (AREA)
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- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Materials For Medical Uses (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
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| US86063706P | 2006-11-21 | 2006-11-21 | |
| US60/860637 | 2006-11-21 |
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| CN200780049872A Division CN101652470A (zh) | 2006-11-21 | 2007-11-20 | 骨髓细胞用于长期培养胰腺胰岛细胞的用途 |
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| CN103992982A true CN103992982A (zh) | 2014-08-20 |
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| CN201410050889.4A Pending CN103992982A (zh) | 2006-11-21 | 2007-11-20 | 骨髓细胞用于长期培养胰腺胰岛细胞的用途 |
| CN200780049872A Pending CN101652470A (zh) | 2006-11-21 | 2007-11-20 | 骨髓细胞用于长期培养胰腺胰岛细胞的用途 |
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| CN200780049872A Pending CN101652470A (zh) | 2006-11-21 | 2007-11-20 | 骨髓细胞用于长期培养胰腺胰岛细胞的用途 |
Country Status (7)
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| US (1) | US20100143306A1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2092057B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP5474559B2 (cg-RX-API-DMAC7.html) |
| CN (2) | CN103992982A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2007321983B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2670289A1 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2008063640A2 (cg-RX-API-DMAC7.html) |
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| JP2013521797A (ja) | 2010-03-17 | 2013-06-13 | 国立大学法人京都大学 | 膵由来非内分泌上皮細胞と血管内皮細胞との組織複合体による膵島様組織の培養法 |
| MX2020014242A (es) * | 2018-06-25 | 2021-05-27 | Imagine Pharma Llc | Composiciones y métodos para propagar las células de islotes productoras de insulina y usos terapéuticos de las mismas. |
| US20240084261A1 (en) * | 2021-02-03 | 2024-03-14 | Symbiocelltech, Llc | Cell Clusters Comprising Stem and Islet Cells, Methods of Making, and Treatment of Diabetes Mellitus Therewith |
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| US6001647A (en) * | 1994-04-28 | 1999-12-14 | Ixion Biotechnology, Inc. | In vitro growth of functional islets of Langerhans and in vivo uses thereof |
| US20050208029A1 (en) * | 2002-04-17 | 2005-09-22 | Akihiro Umezawa | Method of forming pancreatic beta cells from mesenchymal cells |
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2007
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- 2007-11-20 JP JP2009538403A patent/JP5474559B2/ja not_active Expired - Fee Related
- 2007-11-20 CA CA002670289A patent/CA2670289A1/en not_active Abandoned
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- 2007-11-20 CN CN200780049872A patent/CN101652470A/zh active Pending
- 2007-11-20 EP EP07840085.0A patent/EP2092057B1/en not_active Not-in-force
- 2007-11-20 WO PCT/US2007/024258 patent/WO2008063640A2/en not_active Ceased
- 2007-11-20 US US12/515,754 patent/US20100143306A1/en not_active Abandoned
Non-Patent Citations (2)
| Title |
|---|
| HESS D ET AL.: ""Bone Marrow-Derived Stem Cells Initiate Pancreatic Regeneration"", 《NATURE BIOTECHNOLOGY NATURE PUBLISHING GROP》 * |
| LIU ET AL.: ""Adult Bone Marrow Cells Transdifferentiate into Endocrine Cells During Pancreatic Regeneration"", 《BLOOD》 * |
Also Published As
| Publication number | Publication date |
|---|---|
| EP2092057A4 (en) | 2011-04-20 |
| EP2092057A2 (en) | 2009-08-26 |
| JP5474559B2 (ja) | 2014-04-16 |
| WO2008063640A2 (en) | 2008-05-29 |
| WO2008063640A3 (en) | 2008-12-18 |
| EP2092057B1 (en) | 2014-10-15 |
| CA2670289A1 (en) | 2008-05-29 |
| CN101652470A (zh) | 2010-02-17 |
| AU2007321983A1 (en) | 2008-05-29 |
| US20100143306A1 (en) | 2010-06-10 |
| AU2007321983B2 (en) | 2014-05-29 |
| JP2010509936A (ja) | 2010-04-02 |
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