CN103978675A - Medical material surface modification system and medical material surface modification method - Google Patents

Abstract

The invention discloses a medical material surface modification system and a medical material surface modification method, belonging to the technical field of material surface modification. The medical material surface modification system is characterized by jointly consisting of a selectable gas source subsystem, a discharge working port subsystem and a motor transmission control subsystem, wherein the discharge working port subsystem is capable of adjusting the plasma excitation voltage, the frequency and a distance between an upper electrode and a lower electrode along with working gas, and the motor transmission control subsystem is based on the distance between the upper electrode and the lower electrode of a micro processor, objective table feeding, the plasma excitation voltage and the frequency control. The invention correspondingly provides a modification method based on programmable program control. The medical material surface modification system and the medical material surface modification method are suitable for medical materials to be treated with different thicknesses; the working gas can be selected according to the material property and a treatment requirement, and the modification time and a discharge parameter can be selected according to the material thickness; meanwhile, due to the use of an insulation medium sheet, pollution to the materials caused by the electrodes is avoided; a gas flow equalization chamber in the discharge working port replaces a vacuum system, so that the working program is simplified, the equipment cost is lowered, and automatic operation is completely realized.

Description

A kind of medical material surface modification system and method thereof

Technical field

The present invention relates to a kind of medical material surface modifying method and device, be specially a kind of method and device that utilizes the homogeneous dielectric barrier discharge low temperature plasma producing under atmospheric pressure to change the surface property of medical material.

Background technology

When biomaterial for medical purpose contact with human body for a long time, must be fully satisfied and the compatibility of organism environment, there is not with it the bad biological respinses such as any toxicity, sensitization, inflammation, thrombus in organism.These all depend on the interaction of material surface and organism environment.Thereby, effectively control and improve the surface nature of biomaterial, be improve and promote favourable interaction between material surface and organism, suppress disadvantageous interactional critical path, this is also that current medical material is studied at focus.Affect interactional because have the factors such as the composition, surface topography, surface energy state, parent's (dredging) water-based, surface charge of biomaterial surface between material and organism.

At present, reach the common method of improving material surface performance and have wet chemical processing, photochemical method processing, ultra-violet radiation and Cement Composite Treated by Plasma etc. by material surface is processed.Wherein some poisonous chemical reagent that use in wet chemical practice process, not only serious environment pollution, also has great harm to human body more.And the treatment technologies such as photochemical method and ultra-violet radiation method are limited by ray energy, its treatment effect can be controlled.Low temperature plasma process for treating surface is to only hundreds of dusts of the depth of interaction of material surface in contrast, can not affect the character of matrix material, and can process the material surface of various shapes, have technique simple, easy and simple to handle, be easy to control, the advantage such as pollution-free, therefore lower temperature plasma technology is comparatively desirable medical material process for modifying surface.

Plasma is a kind of gaseous material of part or all of ionization, the particles such as the atom that contains metastable state and excitation state, molecule, ion, can with material surface interactions, produce surface reaction, make surface physicochemical change occur and realize surface modification.Plasma surface modification has three types, is respectively plasma surface treatment, plasma surface polymerization and plasma surface grafting.Plasma surface treatment is mainly with the plasma that the inorganic gas of non-polymerization produces, material to be processed.(as in domestic applications numbers 200510126484.5 disclosed " plasma surface processor of multi-capacity coupled radio-frequency ") is inert gas discharge generation plasma under the effect of radio frequency power source in vacuum chamber, excitation state gas molecule be positioned over the material surface interactions in radio-frequency electrode, make material surface realize the effect of sterilization and surface modification.But in concrete enforcement, because the introducing of vacuum system makes operating process very loaded down with trivial details, and exposed radio-frequency electrode can pollute discharge environment in specific implementation process, the radio frequency source in practice, electric discharge being used also has higher parameter and load matched requirement.Plasma surface polymerization is also conventionally under radio frequency or microwave excitation source forcing, to organic gas monomer plasma, make it produce all kinds of groups, thereby between these active groups and between active group monomer, carry out addition reaction and form polymeric membrane and reach the object of material modification.The process of plasma surface glycerol polymerization is that material surface produces active group and forms activated centre after Cement Composite Treated by Plasma, contacts trigger monomer and matrix surface carry out graft polymerization reaction (if domestic applications numbers 201110317878.4 are openly " a kind of macromolecule material surface modification method of plasma processing ") with gas phase or liquid monomer.

The application plasma technique of report carries out surface modification to medical macromolecular materials at present, mainly still concentrate on the low pressure glow discharge plasma technique in vacuum system, if disclosed in interior domestic applications numbers 200710026875.9 " process for treating surface of the macromolecular material of cultivating for cell " is that the cell culture container of finished product is put into plasma processor, under vacuum or negative pressure state, introduce oxygen, nitrogen or other plasma gas, under suitable process conditions, discharge, form plasmasphere at cell culture container inner surface, thereby improve the biocompatibility of macromolecular material.The enforcement weak point of this process is, in whole processing procedure, still need in vacuum system, carry out, the existence of vacuum chamber, on the one hand the manufacture of equipment and maintenance cost are increased greatly, also limited on the other hand the physical dimension of processed workpiece, thereby greatly limit its range of application, and in vacuum system, pass into whole processing procedure after discharge gas and could change other discharge gas after finishing, thereby can only realize single plasma polymerization process or plasma surface treatment process, later stage also needs to be aided with other courses of reaction to reach the biocompatibility of realizing material.

Disclosed in domestic applications 200710090033.X " system of processing thin-film material surface using bi-medium to block electric discharge " is characterized in that, in air by many groups by glass tube or the coated metal tube electrode of earthenware, in the time that electric discharge is carried out, electrode self is also rotating, and can reach through thin-film material the object of surface modification between electrode.This treatment system in specific implementation process in order to realize comparatively gentle even accurate glow discharge, can only be under the minimum electrode gap only passing for film discharge generation plasma, having limited greatly can be for the volume of processing material, need motor or the rotation of thin-film material band moving electrode simultaneously, avoid the local heating of electrode inhomogeneous.The method can only be confined to the surface-treatment applications of part thin-film material.

Summary of the invention

The object of this invention is to provide a kind of medical material surface modifying method and device, adopt this device, by regulation and control working gas gas circuit, can realize freely switching of the reaction such as surface modification and surface aggregate grafting to medical material.

System features of the present invention is, contains: source of the gas subsystem, electric discharge work chamber subsystem and RACS, wherein:

Source of the gas subsystem 1, contains: multichannel steam line, mixed gas tank and tracheae, wherein:

Multichannel steam line 11, in order to the working gas that provides the single channel being convenient to freely switch or multichannel to mix, the steam line described in each road is by forming for controlling needle-valve 111, pressure-reducing valve 112 and gas cylinder 113 serial connections that described working gas switches,

Mixed gas tank 12, air inlet is connected by tracheae with the gas outlet of needle-valve described in each 111, the gas outlet of described mixed gas tank 12 is connected by tracheae with the flowmeter 132 in air inlet 1511, the casing at the casing back side successively, the gas outlet of described flowmeter 132 communicates with the air admission hole 142 of the gas flow equalization chamber 1510 in plasma generation operating mechanism by tracheae, so that described gas discharge produces plasma

Electric discharge work chamber subsystem, it is the plasma generation operating mechanism described in, contain: top fixed-wing 151, top electrode 152, sliding rail 153, bottom electrode 154, output voltage are that 1kV～30kV, frequency are 5kHz～16kHz plasma excitation power supply 155 and insulation barrier 156, wherein:

Bottom electrode 154 upper surfaces closely post thickness be under 1mm～3mm described in dielectric sheet 157 bottom electrode 154 be jointly connected with described casing and ground connection by wire and the low-pressure end of described plasma excitation power supply 155, the left and right sides of described lower dielectric sheet 157, closely be embedded in respectively in the sliding rail 153 described in corresponding two, jointly form an objective table

Top electrode 152 lower surfaces are glued with the upper dielectric sheet 158 that thickness is 0.3mm～3mm, described top electrode 152 is connected with the high-pressure side of described plasma excitation power supply by wire, the lower surface of the upper surface of top electrode 152 and described top fixed-wing 151 is fixedly affixed

Insulation barrier 16, arranged on left and right sides respectively has one, the described insulation barrier in left side has the air admission hole 142 of described gas flow equalization chamber 1510 in the horizontal direction, side insulation right baffle plate has array venthole in the horizontal direction, described left and right two insulation boards 16 are longitudinally close to the outside of described top fixed-wing 151 and the outside of described sliding rail from top to bottom

Described left and right two insulation barriers 1561,1562 inner side, the lower surface of upper dielectric sheet 158, the upper surface of lower dielectric sheet 157 and two of left and right sliding rail 1531, space segment between 1532 upper surface has formed described gas flow equalization chamber 1510 jointly, form an electric discharge work chamber

RACS, at least contains and controls motor 17 and microprocessor 18, wherein:

Control motor 17, contain: first controls motor 171 and second controls motor 172, wherein:

First controls motor 171, output shaft is coaxially connected with the leading screw 159 that is arranged on described top fixed-wing 151 upper surfaces, for controlling the gap between described upper dielectric sheet 158 and lower dielectric sheet 157, realizes the control of vertical interval between upper/lower electrode, adjustable range is 3mm～10mm

Second controls motor 172, by the horizontal slip of two the described sliding rails 1531,1532 in about output shaft synchronous control, realizes described objective table and pass in and out the control of described electric discharge work chamber,

Microprocessor 18, in the default processing time, unit be second, and two control electrodes described in flow-control scope control, is wherein provided with:

For the first described control motor 171, default:

The initial separation that described upper/lower electrode is 152,154

Described working gas classification---leading screw 159 displacements---is controlled the mapping table between voltage

For described the second control electrode 172, default:

The initial position of described sliding rail 153 and range thereof,

For described plasma excitation power supply 155, default:

Described working gas classification---plasma excitation voltage---processing time three's mapping table

Described microprocessor 18 is also provided with following input:

Described first controls the control voltage input end of motor 171 and the upper and lower displacement amount feedback input end of described leading screw 159,

Described second controls the control voltage input end of motor 172 and the horizontal displacement feedback input end of described sliding rail 153

The voltage controling value input of described plasma excitation power supply 155 and FREQUENCY CONTROL value input,

Described microprocessor 18 is also provided with following output:

Described first controls the magnitude of voltage output of motor 171, and in the time that the upper and lower displacement amount of described leading screw 159 reaches setting value, described output voltage is zero,

Described second controls the magnitude of voltage output of motor 172, and in the time that the horizontal displacement of described sliding rail 153 reaches setting value, described output voltage is zero,

Set plasma excitation magnitude of voltage output and the frequency values output of working gas, arrive the described processing time, the output valve of two described voltage and frequency is zero simultaneously.

Be provided with: front panel, rear board and left and right sides panel, wherein:

Front panel 21 is provided with: work hatch door 211 and control panel 212:

Work hatch door 211, is positioned at described objective table front end,

On control panel 212, be provided with:

The digital display meter head 213 of the output voltage values of described plasma excitation voltage source 155 and the frequency values digital display meter head 214 of this output voltage, and corresponding voltage-regulation button 215 and frequency adjustment button 216, wherein: described voltage-regulation button 215 outputs are connected with the plasma excitation voltage controling value input on described microprocessor 18, described frequency adjustment button 216 outputs are connected with corresponding described FREQUENCY CONTROL value input

Described first controls the control voltage-regulation button 217 of motor 171, and output is connected with the described first control voltage input end of controlling motor 171 on described microprocessor 18,

Described second controls the control voltage-regulation button 218 of motor 172, and output is connected with the described second control voltage input end of controlling motor 172 on described microprocessor 18,

Flow-rate adjustment button (219) is for the flow of adjust flux meter (132), and shows by flowmeter dial plate (221),

LCDs 222, input is connected with the output of the CCD camera that is fixed on described front panel 21 back sides, and the optical fiber camera of described CCD camera is inserted into and in the insulation barrier 156 described in described any, faces the inner place of described electric discharge work chamber,

On left and right sides panel 231,232, have louvre 2311,

On rear board 24, be provided with: power switch 241, air inlet 1511 and fan outlet 242.

A kind of medical material surface modifying method, is characterized in that, contains successively following steps:

Step (1), turns on the power switch 241, by the control voltage-regulation button 217 of described the first control motor 171, regulates the spacing of described upper dielectric sheet 158 and described objective table to adapt to the size of pending medical material;

Step (2), pulls out described objective table by the described second control voltage-regulation button 218 of controlling motor 172, described pending medical material is positioned on described objective table, more described objective table is sent in electric discharge work chamber;

Step (3), to the working gas that passes into appointment in described electric discharge work chamber;

Step (4), regulate described plasma excitation voltage-regulation button 215 and frequency adjustment button 216, input and the corresponding plasma excitation voltage of working gas and frequency values, carry out surface modification or surface aggregate or surface grafting processing to described pending medical material;

Step (5), arrived after the processing time of setting, and turn-offed corresponding pressure-reducing valve and the needle-valve of working gas, disconnected working gas, and pull-out objective table, takes out the described medical material of handling well, after described objective table and leading screw are resetted, and powered-down switch.

Advantage applies of the present invention realizes automatically and controlling at (1) plasma generator device, can automatically adjust suitable discharge space for the pending material of different-thickness, not only can effective and reasonablely utilize working gas, electric discharge modification time and discharge parameter that also can the pending material of reasonably optimizing; (2) pending material is placed in the middle of two insulating medium layers, has avoided the pollution of electrode pair material, the working life that has also effectively extended reaction unit simultaneously; (3) provide working gas by gas flow equalization chamber to work chamber, can make working gas be uniformly distributed in work chamber, improved greatly the uniformity of the plasma of working gas discharge generation; (4) work chamber has removed the parcel of vacuum system, has simplified greatly the working procedure of plasma surface modification, greatly reduces the cost of plasma surface modification equipment; (5) farthest realized the automation of installing, comprised that the automatic control of discharge space in work chamber regulates, the automatic control of objective table regulates, thereby makes the modifying process of material more accurately controlled, has reduced the operation easier of plasma surface modification device.

Brief description of the drawings

Fig. 1 is the structural representation of the embodiment of the present invention;

Fig. 2 is that operating mechanism's schematic diagram occurs the plasma of the embodiment of the present invention;

Fig. 3 is the plasma generator structural representation of the embodiment of the present invention;

Fig. 4 is the casing front view of the embodiment of the present invention;

Fig. 5 is the casing rear view of the embodiment of the present invention;

Fig. 6 is the hydrophilically modified front and back of embodiment contact angle contrast photo: (a) before surface modification, (b) after surface modification;

Fig. 7 is RACS block diagram.

Detailed description of the invention

Below in conjunction with accompanying drawing, embodiments of the invention are described in detail, thereby so that advantages and features of the invention can be easier to be it will be appreciated by those skilled in the art that protection scope of the present invention is made more clearly and being defined.

Embodiment: medical zirconia is cultivated substrate surface modification

Work base material adopts medical zirconia to cultivate substrate, object is to improve surperficial hydrophilicity, unlatching is positioned at the power switch 241 at the casing back side, and regulating the distance between top electrode 152 and insulating barrier 158 and bottom objective table by the self-control button 217 on the control panel 212 of front panel 21 right-hand members is 3mm; Shift out work chamber objective table by the self-control button 218 on control panel 212, medical zirconia is cultivated to substrate and be positioned on objective table, by the self-control button on control panel, objective table is sent back in work chamber; In work chamber, pass into helium; Regulate the voltage knob 215 on control panel, input service voltage 4.4kV discharge generation plasma, cultivates substrate surface treatment 30s to medical zirconia; Regulation voltage knob 215, closes input voltage, disconnects working gas, and output objective table takes out the medical zirconia of handling well and cultivates substrate, and objective table is sent back in work chamber, and powered-down switch, completes whole processing procedure.

Consulting the working gas that Fig. 1 is different is contained in different gas cylinder 113, on gas cylinder, be provided with pressure-reducing valve 112, the gas outlet end of pressure-reducing valve 112 is connected with mixed gas tank 12 by gas pipeline, and single channel steam line is provided with the needle-valve 111 of controlling gas break-make for free switch operating gas; In mixed gas tank, be connected with the air inlet 131 at the casing back side, air inlet 131 is connected with the flowmeter 132 in casing by tracheae, and the air admission hole 142 that the flowmeter 132 in casing is 8mm by tracheae with gas flow equalization chamber 141 1 lateral apertures in plasma generation operating mechanism is connected; Be that 11mm array venthole 122 evenly flows in work chamber for discharge generation plasma by aperture again.

Consult Fig. 1 to Fig. 5, the control function of front panel is controlled by the programmable control system 18 in casing, top electrode 152 and upper insulating barrier 158 are fixed on top fixed-wing 151 times, two rhizoid thick sticks 159 are installed on fixed-wing 151, and control system 18 realizes the vertical upgrade function of top electrode 152 and upper insulating barrier 158 by controlling motor 171; Objective table is made up of sliding rail 153 and the lower dielectric sheet 157 of both sides, and sliding rail 153 is connected with motor 172, and control system 18 realizes objective table turnover work chamber by controlling the rotation of motor 172.

Upper surface and lower dielectric sheet 157 lower surfaces of consulting Fig. 3 plasma generator bottom electrode 154 are closely affixed, bottom electrode is connected with the high-pressure stage of plasma excitation power supply module 155 by high-voltage conducting wires, top electrode 152 lower surfaces closely attach mutually with upper insulating medium layer 158, top electrode is connected with plasma excitation power supply module 155 ground electrodes by wire, the ground connection that is simultaneously connected with casing, the insulation barrier 156 of generator both sides and gas flow equalization chamber 141 and upper insulating barrier and lower insulation plate form the work chamber 15 that discharges jointly.

Consult Fig. 4 and Fig. 5 casing front panel 21 left sides are provided with work chamber hatch door 211, work chamber hatch door is fixed on objective table front end, front panel 21 right sides are provided with automatically can control panel, has the frequency values digital display meter head 214 of digital display meter head 213, this output voltage of the output voltage values of plasma excitation voltage source 155 and corresponding voltage-regulation button 215 and frequency adjustment button 216, LCDs 222, first to control the control voltage-regulation button 217 of motor 171, Flow-rate adjustment knob 219 for controlling the input flow rate of flowmeter on automatic control panel; The casing left and right sides has louvre 2311; Casing rear board 24 lower ends are provided with power switch 241, air inlet 131 and fan mouth 242.

Consulting the medical zirconia material of Fig. 6 is 78 degree putting into the water contact angle before 157 modifications of dielectric sheet under objective table, and through helium, after discharge process 30s under 4.4kV operating voltage excitation, the water contact angle that records this material surface is 32 degree.

Embodiment hydrophilicity detects data three times

The above; it is only the specific embodiment of the present invention; but the scope of protection of the invention is not limited to this; any those of ordinary skill in the art are in the disclosed technical scope of the present invention; the variation of expecting without creative work and replacement, within all should being encompassed in protection scope of the present invention.Therefore the protection domain that, protection scope of the present invention should be limit with claims is as the criterion.

Claims (3)

1. a medical material surface modification system, is characterized in that, contains: source of the gas subsystem, electric discharge work chamber subsystem and RACS, wherein:

Source of the gas subsystem (1), contains: multichannel steam line, mixed gas tank and tracheae, wherein:

Multichannel steam line (11), in order to the working gas that provides the single channel being convenient to freely switch or multichannel to mix, steam line described in each road is formed by the needle-valve (111) for controlling described working gas switching, pressure-reducing valve (112) and gas cylinder (113) serial connection

Mixed gas tank (12), air inlet is connected by tracheae with the gas outlet of needle-valve described in each (111), the gas outlet (121) of described mixed gas tank (12) is connected by tracheae with the flowmeter (132) in air inlet (1511), the casing at the casing back side successively, the gas outlet of described flowmeter (132) communicates with the air admission hole (142) of the gas flow equalization chamber (1510) in plasma generation operating mechanism by tracheae, so that described gas discharge produces plasma

Electric discharge work chamber subsystem, it is the plasma generation operating mechanism described in, contain: top fixed-wing (151), top electrode (152), sliding rail (153), bottom electrode (154), output voltage are that 1kV～30kV, frequency are 5kHz～16kHz plasma excitation power supply (155) and insulation barrier (156), wherein:

It is dielectric sheet (157) under 1mm～3mm that bottom electrode (154) upper surface closely posts thickness, described bottom electrode (154) is connected with described casing and ground connection jointly by wire and the low-pressure end of described plasma excitation power supply (155), the left and right sides of described lower dielectric sheet (157) is closely embedded in respectively in the sliding rail (153) described in corresponding two, jointly form an objective table

Top electrode (152) lower surface is glued with the upper dielectric sheet (158) that thickness is 0.3mm～3mm, described top electrode (152) is connected with the high-pressure side of described plasma excitation power supply by wire, the lower surface of the upper surface of top electrode (152) and described top fixed-wing (151) is fixedly affixed

Insulation barrier (156), arranged on left and right sides respectively has one, the described insulation barrier in left side has the air admission hole (142) of described gas flow equalization chamber (1510) in the horizontal direction, side insulation right baffle plate has array venthole in the horizontal direction, described left and right two insulation boards (1561,1562) be longitudinally close to from top to bottom the outside of described top fixed-wing (151) and the outside of described sliding rail

Described left and right two insulation barriers (1561,1562) inner side, the lower surface of upper dielectric sheet (158), the upper surface of lower dielectric sheet (157) and two of left and right sliding rail (1531,1532) space segment between upper surface has formed described gas flow equalization chamber (1510) jointly, form an electric discharge work chamber

RACS, at least contains and controls motor (17) and microprocessor (18), wherein:

Control motor (17), contain: first controls motor (171) and second controls motor (172), wherein:

First controls motor (171), output shaft is coaxially connected with the leading screw (159) that is arranged on described top fixed-wing (151) upper surface, be used for controlling the gap between described upper dielectric sheet (158) and lower dielectric sheet (157), realize the control of vertical interval between upper/lower electrode, adjustable range is 3mm～10mm

Second controls motor (172), by the horizontal slip of two the described sliding rails in about output shaft synchronous control (1531,1532), realizes described objective table and pass in and out the control of described electric discharge work chamber,

Microprocessor (18), in the default processing time, unit be second, and two control electrodes described in flow-control scope control, is wherein provided with:

For the first described control motor (171), default:

Initial separation between described upper/lower electrode (152,154)

Described working gas classification---leading screw (159) displacement---is controlled the mapping table between voltage

For described the second control motor (172), default:

Initial position and the range thereof of described sliding rail (153),

For described plasma excitation power supply (155), default:

Described working gas classification---plasma excitation voltage---processing time three's mapping table

Described microprocessor (18) is also provided with following input:

Described first controls the control voltage input end of motor (171) and the upper and lower displacement amount feedback input end of described leading screw (159),

Described second controls the control voltage input end of motor (172) and the horizontal displacement feedback input end of described sliding rail (153)

The voltage controling value input of described plasma excitation power supply (155) and FREQUENCY CONTROL value input,

Described microprocessor (18) is also provided with following output:

Described first controls the magnitude of voltage output of motor (171), and in the time that the upper and lower displacement amount of described leading screw (159) reaches setting value, described output voltage is zero,

Described second controls the magnitude of voltage output of motor (172), and in the time that the horizontal displacement of described sliding rail (153) reaches setting value, described output voltage is zero,

Set plasma excitation magnitude of voltage output and the frequency values output of working gas, arrive the described processing time, the output valve of two described voltage and frequency is zero simultaneously.

2. a kind of medical material surface modification system according to claim 1, is characterized in that, is provided with: front panel, rear board and left and right sides panel, wherein:

Front panel (21) is provided with: work hatch door (211) and control panel (212):

Work hatch door (211), is positioned at described objective table front end,

Control panel (212) is upper, is provided with:

The digital display meter head (213) of the output voltage values of described plasma excitation voltage source (155) and the frequency values digital display meter head (214) of this output voltage, and corresponding voltage-regulation button (215) and frequency adjustment button (216), wherein: described voltage-regulation button (215) output is connected with the plasma excitation voltage controling value input on described microprocessor (18), described frequency adjustment button (216) output is connected with corresponding described FREQUENCY CONTROL value input

Described first controls the control voltage-regulation button (217) of motor (171), and output is connected with the described first control voltage input end of controlling motor (171) on described microprocessor (18),

Described second controls the control voltage-regulation button (218) of motor (172), and output is connected with the described second control voltage input end of controlling motor (172) on described microprocessor (18),

Flow-rate adjustment button (219) is for the flow of adjust flux meter (132), and shows by flowmeter dial plate (221),

LCDs (222), input is connected with the output of the CCD camera that is fixed on described front panel (21) back side, the optical fiber camera of described CCD camera is inserted into and in the insulation barrier (156) described in described any, faces the inner place of described electric discharge work chamber

On left and right sides panel (231,232), have louvre (2311),

Rear board (24) is upper, is provided with: power switch (241), air inlet (1511) and fan outlet (242).

3. the medical material surface modifying method proposing according to a kind of medical material surface modification system described in claim 1 and 2, is characterized in that, contains successively following steps:

Step (1), turn on the power switch (241), by the control voltage-regulation button (217) of described the first control motor (171), regulate the spacing of described upper dielectric sheet (158) and described objective table to adapt to the size of pending medical material;

Step (2), pull out described objective table by the described second control voltage-regulation button (218) of controlling motor (172), described pending medical material is positioned on described objective table, more described objective table is sent in electric discharge work chamber;

Step (3), to the working gas that passes into appointment in described electric discharge work chamber;

Step (4), regulate described plasma excitation voltage-regulation button (215) and frequency adjustment button (216), input and the corresponding plasma excitation voltage of working gas and frequency values, carry out surface modification or surface aggregate or surface grafting processing to described pending medical material;

Step (5), arrived after the processing time of setting, and turn-offed corresponding pressure-reducing valve and the needle-valve of working gas, disconnected working gas, and pull-out objective table, takes out the described medical material of handling well, after described objective table and leading screw are resetted, and powered-down switch.