CN103977305A - Pharmaceutical composition, pharmaceutical preparation and application thereof - Google Patents
Pharmaceutical composition, pharmaceutical preparation and application thereof Download PDFInfo
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- CN103977305A CN103977305A CN201410214266.6A CN201410214266A CN103977305A CN 103977305 A CN103977305 A CN 103977305A CN 201410214266 A CN201410214266 A CN 201410214266A CN 103977305 A CN103977305 A CN 103977305A
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Abstract
The invention discloses a pharmaceutical composition which is prepared from the following raw materials in parts by weight: 100 parts of deerskin, 50-150 parts of tortoise plastron, 30-100 parts of ginseng, 30-100 parts of medlar, 30-100 parts of fleece-flower roots, 20-100 parts of malt, 20-100 parts of medicated leaven, 20-100 parts of semen cuscutae and 20-100 parts of white poria. In addition, the invention further provides a pharmaceutical preparation and an application of the pharmaceutical composition and the pharmaceutical preparation in preparing health products. Shown as the embodiment, the pharmaceutical composition or the pharmaceutical preparation disclosed by the invention is taken to effectively alleviate stains and wrinkles caused by old age and have a remarkable improving effect on rough skins, pale complexion, grayish complexion and chlorosis.
Description
Technical field
The present invention relates to a kind of pharmaceutical composition, the pharmaceutical preparation of being prepared by this pharmaceutical composition, and described pharmaceutical composition, described pharmaceutical preparation are in the application of preparing in health product.
Background technology
The epoch that The nation is prosperous and the people are strong and powerful make people's economic level have significant raising, but follow the quickening of rhythm of life, have also accelerated the aging of body.Especially the people who steps into person in middle and old age is increasing, adds diet inharmonious, through wrecking of years, drink fake wine, eat hormone meat, have vegetable of toxin etc., brought serious harm to the mankind's health.Immunity of organisms declines, and occurs the dysfunction of each system in health, also occurs a series of incurable disease.
Summary of the invention
The object of this invention is to provide and a kind ofly can improve human organism's immunocompetence, improve fatigue symptom, delay the pharmaceutical composition of body aging, and the pharmaceutical preparation being prepared from by this pharmaceutical composition.
To achieve these goals, on the one hand, the invention provides a kind of pharmaceutical composition, wherein, this pharmaceutical composition is prepared from by following raw material: Corium Cervi, Carapax et Plastrum Testudinis, Radix Ginseng, Fructus Lycii, Fructus Hordei Germinatus, Massa Medicata Fermentata, the Radix Polygoni Multiflori, Semen Cuscutae and Poria, wherein, with respect to the Corium Cervi of 100 weight portions, the content of Carapax et Plastrum Testudinis is 50-100 weight portion, the content of Radix Ginseng, the Fructus Lycii fleece-flower root 30-100 weight portion of respectively doing for oneself, Fructus Hordei Germinatus, the content of Massa Medicata Fermentata, Semen Cuscutae and the Poria 20-100 weight portion of respectively doing for oneself.
Preferably, the Corium Cervi that described Corium Cervi is Cervus nippon Temminck and/or the Corium Cervi of Cervus elaphus linnaeus.
On the other hand, the present invention also provides a kind of pharmaceutical preparation, and this pharmaceutical preparation contains active component, and pharmaceutically acceptable adjuvant alternatively, and wherein, described active component is above-described pharmaceutical composition.
Preferably, the preparation method of described pharmaceutical preparation comprises, Corium Cervi and Carapax et Plastrum Testudinis are brewed into glue, respectively Radix Ginseng, Fructus Lycii, Fructus Hordei Germinatus, Massa Medicata Fermentata, the Radix Polygoni Multiflori, Semen Cuscutae and Poria is fried into medicinal liquid; Described glue, each medicinal liquid and optional pharmaceutically acceptable adjuvant are mixed.
On the one hand, the invention provides pharmaceutical composition as above again, pharmaceutical preparation as above is in the application of preparing in health product.
By taking pharmaceutical composition provided by the invention or pharmaceutical preparation, as shown in the Examples, can effectively weaken the mottle, the wrinkle that are caused by the geratic period, and, pale complexion coarse to skin, dark stagnant, sallow and emaciation and sallow complexion are all significantly improved effect.
Other features and advantages of the present invention are described in detail the detailed description of the invention part subsequently.
Detailed description of the invention
Below the specific embodiment of the present invention is elaborated.Should be understood that, detailed description of the invention described herein only, for description and interpretation the present invention, is not limited to the present invention.
On the one hand, the invention provides a kind of pharmaceutical composition, wherein, this pharmaceutical composition is prepared from by following raw material: Corium Cervi, Carapax et Plastrum Testudinis, Radix Ginseng, Fructus Lycii, Fructus Hordei Germinatus, Massa Medicata Fermentata, the Radix Polygoni Multiflori, Semen Cuscutae and Poria, wherein, with respect to the Corium Cervi of 100 weight portions, the content of Carapax et Plastrum Testudinis is 50-100 weight portion, the content of Radix Ginseng, the Fructus Lycii fleece-flower root 30-100 weight portion of respectively doing for oneself, Fructus Hordei Germinatus, the content of Massa Medicata Fermentata, Semen Cuscutae and the Poria 20-100 weight portion of respectively doing for oneself.
Preferably, with respect to the Corium Cervi of 100 weight portions, the content of Carapax et Plastrum Testudinis is 55-90 weight portion, the content of Radix Ginseng, the Fructus Lycii fleece-flower root 40-70 weight portion of respectively doing for oneself, Fructus Hordei Germinatus, the content of Massa Medicata Fermentata, Semen Cuscutae and the Poria 30-75 weight portion of respectively doing for oneself.
According to the present invention, the state of the each raw material for the preparation of aforementioned pharmaceutical compositions is had no particular limits, for example, can be pulverulence, can be also the liquid condition boiling, these those skilled in the art all can select according to practical situation.According to the present invention, the described raw material of preparing described compositions is preferably pulverulence, and described powder is preferably and can passes through the siftage of 80-150 mesh sieve, more preferably can pass through the siftage of 100-120 mesh sieve.
Described Corium Cervi is preferably the Corium Cervi of Cervus nippon Temminck (Cervus nippon Temminck) and/or the Corium Cervi of Cervus elaphus linnaeus (Cervus elaphus L.).Source for described Corium Cervi in the present invention has no particular limits, and for example, can on market, buy the Corium Cervi having cooked for the present invention, also can obtain by conventional concocting method, for example, by fresh Corium Cervi dry in the sun, oven dry or calcine.The method of described calcine is conventionally known to one of skill in the art, does not repeat them here.
Carapax et Plastrum Testudinis: sternite and the carapace of Testudinidae animal Testudinis (chinemys reevesii), the hard tranquillizing and subduing of Carapax et Plastrum Testudinis matter; There is nourishing YIN for suppressing the hyperactive YANG, reinforcing the kidney to strengthen the bone, tranquilizing by nourishing the heart, effect of regulating menstruation, hemostasis, cures mainly hyperactivity of YANG due to deficiency of YIN, vertigo and tinnitus; Hyperactivity of fire caused by deficiency of YIN, osteopyrexia and fever, night sweat seminal emission; Stirring of wind due to deficiency of YIN, wriggling of the limbs; Deficiency of kidney yin, soreness of the waist and knees, lack of preservation of spirit, palpitation with fear fidgets due to deficiency, insomnia forgetfulness; Menses imbalance, hematemesis and epistaxis, menorrhagia, stomachache, bleeding not during menses.
Radix Ginseng: dry root and the rhizome of Araliaceae Radix Ginseng (Panax ginseng C.A.Mey.).More than excavating autumn, after cleaning, dry or dry.
Main root is spindle or cylindrical.Surface lark, top or all have meagre interrupted thick band and obvious vertical wrinkle, and raw most elongated fibrous roots, on fibrous root, often have unconspicuous tiny excipuliform outstanding.Many contractures and bending, tool adventitious root and sparse recess shape stem trace.Matter is harder, section yellowish white, and aobvious mealiness, cambium layer ring grain brown color, there be point-like resin canal and the radial crack of yellowish-brown in skin zone.Fragrance is special, mildly bitter flavor, sweet.Or many, the diamond-shapeds closely isometric or shorter, cylindrical with rhizome of main root or herringbone.Surface lark, tool is indulged wrinkle, and there is ring grain top or middle and lower part.Fibrous root is few and elongated, clear random, has obvious verruca.Rhizome is elongated, minority tubbiness, middle and upper part tool stem trace that is sparse or intensive and that get deeply stuck in.Adventitious root is thinner, how sagging.
Fructus Lycii: the dry mature fruit of plant of Solanaceae lycium barbarum (Lycium barbarum L.).Summer, autumn gather when two seasons, fruit took on a red color, and hot-air seasoning, removes carpopodium, or dry in the air to rhicnosis, dry, and remove carpopodium.
This product is class spindle or ellipse.Surface redness or kermesinus, there is the stylar scar of kick shape on top, the carpopodium trace of base portion adularescent.Peel is pliable and tough, shrinkage; Sarcocarp meat, soft and moist.Class kidney shape, flat and stick up, the light yellow or brown color in surface.Feeble QI, taste is sweet.
Fructus Hordei Germinatus: the Preparation process product of the mature fruit of grass Fructus Hordei Vulgaris (Hordeum vulgare L.) through germinateing dry.After wheat grain is soaked in water, keep suitable temperature, humidity, in the time that plumelet grows to about 5mm left and right, dry or cold drying.
This product is fusiformis.Surface is faint yellow, and the back side is that lemma surrounds, tool 5 arteries and veins; The outside of belly is that glumelle surrounds.Remove after flower glume, the outside of belly has 1 longitudinal furrow; Base portion radicle place bears plumelet and fibrous root, and plumelet length is draped over one's shoulders needle-like bar shaped.Fibrous root several, very thin and bending.Matter is hard, section white, mealiness.Feeble QI, taste is micro-sweet.
Massa Medicata Fermentata claims again Massa Medicata Fermentata: (Massa Medicata Fermentata) is after flour, wheat bran etc. mix, the herbal leaven forming through fermentation, for example, Fuqu.The method of described preparation is conventionally known to one of skill in the art, does not repeat them here.
Radix Polygoni Multiflori: the dried root of polygonaceae plant (Polygonum multiflorum Thunb.).Autumn, two season of winter excavate when leaf is withered, and the two ends of pruning are cleaned, and the individual large piece that is cut into is dry.
This product is lumps or irregular spindle.Brown or the bronzing of surface red, shrinkage injustice, has shallow ridges, and grow crosswise hole skin sample projection and radicula trace.Body weight, matter is solid, not frangibility, section light yellowish brown or pale red brown, aobvious mealiness, forms Nanjing brocade shape decorative pattern, and central woody part is larger, and what have is core.Feeble QI, mildly bitter flavor and sweet puckery.
Semen Cuscutae: the dry mature seed of convolvulaceous plant south Semen Cuscutae (Cuscuta australis R.Br.) or Semen Cuscutae (Cuscuta chinensis Lam.).The plant of gathering when fruit maturation autumn, shine in, lay seed, remove impurity.
It is spherical that this product is class.Surface taupe brown is to sepia, and coarse, hilum is linear or oblate.Matter is solid, and not easy-to-use fingernail crushes.Feeble QI, lightly seasoned.
Poria: the medicinal part of plant Poria (Smilax china L), Poria piece cuts the white portion after Poria.
Have another name called Buddha's warrior attendant pocket, Rhizoma Smilacis Scobinicaulis etc., belong to Liliales, Liliaceae climbing shrub, dredges raw thorn, flower green-yellow, and redness when ripe, has Refined Mercurous chloride.Its root stock can extract starch and tannic extract, or is used for making wine.
Source to above-mentioned various raw materials in the present invention has no particular limits, and for example, can on market, buy the product having cooked, and also can obtain by conventional concocting method, for example, can make by raw material is dried and is ground.Dry method can, for drying or naturally drying, be preferably nature and dry.The method of grinding can be the Ginding process of field of Chinese medicines routine, and the condition optimization of grinding makes described raw material can pass through the powder of 80-150 object sieve aperture, preferably can pass through 100-120 object sieve aperture.
According to the present invention, the method for being prepared described compositions by above raw material has no particular limits, and can be the method for the pharmaceutical compositions of this area routine, for example, after can directly mixing, obtains.
Second aspect, the present invention also provides a kind of pharmaceutical preparation, and this pharmaceutical preparation contains active component, and pharmaceutically acceptable adjuvant alternatively, and wherein, described active component is above-described pharmaceutical composition.
According to the present invention, can by described active component and alternatively pharmaceutically acceptable adjuvant be prepared into any type of pharmaceutical preparation.For example, can be pill, capsule or unguentum.Described pharmaceutically acceptable adjuvant can specifically be selected according to the dosage form of prepared pharmaceutical preparation, described selection according to being conventionally known to one of skill in the art, do not repeat them here.And well known to a person skilled in the art, adding of described adjuvant can't exert an influence to the drug effect of pharmaceutical preparation.
According to the present invention, when in the situation that described pharmaceutical preparation contains pharmaceutically acceptable adjuvant, taking the gross weight of pharmaceutical preparation as benchmark, the content of described active component can be 30-80 % by weight, be preferably 50-70 % by weight, the content of described adjuvant can be 20-70 % by weight, is preferably 30-50 % by weight.
The present invention has no particular limits the preparation method of described pharmaceutical preparation, after above each raw material can being mixed, is prepared again, after also can boiling respectively, remixes preparation.But the present inventor finds, Corium Cervi and Carapax et Plastrum Testudinis are brewed into glue, respectively Radix Ginseng, Fructus Lycii, Fructus Hordei Germinatus, Massa Medicata Fermentata, the Radix Polygoni Multiflori, Semen Cuscutae and Poria is fried into medicinal liquid; Described glue, each medicinal liquid and optional pharmaceutically acceptable adjuvant are mixed, can better realize object of the present invention to prepare described pharmaceutical preparation.
Wherein, described in the method that boils can be any method boiling well known in the art, the present invention does not repeat them here.
According to the present invention, for the ease of the preservation of described pharmaceutical preparation, its preparation method also comprises that the medicinal liquid being mixed to get is put into homogenizer carries out homogenizing processing, then the medicinal liquid after homogenizing is concentrated, until " extension flag ", after solution to be concentrated natural cooling, take out and be cut into small pieces, shady and cool place is dry both to be obtained.
On the one hand, the present invention also provides pharmaceutical composition as above again, and pharmaceutical preparation as above is in the application of preparing in health product.
According to the present invention, described health product can be the health product of health product, the health product that improve fatigue symptom, looks improving and the skin nourishing and/or the slow down aging of raising immunity, quickening health product that weak patient recovers after being ill etc.
Below will describe the present invention by embodiment.
One, embodiment/comparative example
After respectively Carapax et Plastrum Testudinis, Radix Ginseng, Fructus Lycii, Fructus Hordei Germinatus, Massa Medicata Fermentata, the Radix Polygoni Multiflori, Semen Cuscutae and Poria being dried, grind, and screen with 120 object screen clothes, and select the siftage of each raw material for the preparation of pharmaceutical composition of the present invention.
Table 1
| Embodiment | Embodiment 1 | Embodiment 2 | Embodiment 3 | Embodiment 4 | Embodiment 5 | Comparative example 1 | Comparative example 2 | Comparative example 3 |
| Numbering | A1 | A2 | A3 | A4 | A5 | D1 | D2 | D3 |
| Corium Cervi | 100 | 100 | 100 | 100 | 100 | --- | 100 | 100 |
| Carapax et Plastrum Testudinis | 55 | 90 | 120 | 50 | 150 | 55 | --- | 55 |
| Radix Ginseng | 90 | 60 | 40 | 100 | 30 | 90 | 90 | --- |
| Fructus Lycii | 65 | 40 | 90 | 30 | 100 | 65 | 65 | 65 |
| Fructus Hordei Germinatus | 30 | 55 | 75 | 20 | 98 | 30 | 30 | 30 |
| Massa Medicata Fermentata | 75 | 60 | 32 | 95 | 22 | 75 | 75 | 75 |
| The Radix Polygoni Multiflori | 90 | 40 | 76 | 28 | 105 | 90 | 90 | 90 |
| Semen Cuscutae | 30 | 75 | 70 | 100 | 20 | 30 | 30 | 30 |
| Poria | 65 | 33 | 75 | 105 | 18 | 65 | 65 | 65 |
Carry out the preparation of pharmaceutical preparation according to each composition of table 1, concrete,
(1) Corium Cervi of embodiment 1,4 and 5 and comparative example 1-3 is the Corium Cervi of Cervus nippon Temminck, the Corium Cervi that embodiment 2 is Cervus elaphus linnaeus, the Corium Cervi that embodiment 2 is Cervus nippon Temminck and the Corium Cervi of Cervus elaphus linnaeus.
(2) clean Corium Cervi is put into and is cut into elongated strip; With meat grinder rubbing, Carapax et Plastrum Testudinis flowing water is cleaned, and after pulverizing, cooks together with Corium Cervi; Add enough water to flooding face, slow fire heating keeps micro-boiling 24 hours, leaches glue, so repeatedly decocts 5 times, to fully enduring out glue; Merge the glue of enduring each time, by 4 layers of filtered through gauze, add the Alumen of 0.08 volume %, stir, precipitate and refilter for 2 hours;
By Radix Ginseng, Fructus Lycii, Fructus Hordei Germinatus, Massa Medicata Fermentata, the Radix Polygoni Multiflori, Semen Cuscutae, Poria, use respectively moisture fried, get fried liquid, remove slag.
As above glue and each fried liquid are merged, put into pressure homogenizer and carry out homogenizing processing, the mixed liquor after homogenizing is concentrated, until " hanging flag " take out and be cut into small pieces after product natural condensation to be concentrated, dry in the shade.Obtain respectively the pharmaceutical preparation B1-B5 corresponding with embodiment 1-5 difference, and the pharmaceutical preparation E1-E3 corresponding with comparative example 1-3 difference.
It should be noted that herein, for the preparation of pharmaceutical preparation of comparative example 1 that does not contain Corium Cervi, carry out according to the method for embodiment 1, different, the mixed glue solution that boils Corium Cervi and Carapax et Plastrum Testudinis is replaced with to the glue that only boils Carapax et Plastrum Testudinis.
Two, test case
1, the mottle that the geratic period caused, wrinkle improve effect
Select 320 to there is the 45-70 year female patient of mottle, wrinkle symptom in various degree, be divided at random 8 treatment groups (every group of 40 patients).5 treatment group drug administration preparation B1-B5 respectively, 3 matched group drug administration preparation E1-E3 respectively, instructions of taking be every day sooner or later respectively once, each 6g, boiled water is oral, observing effect after 100 days, compared with before taking medicine, what symptom disappeared completely is labeled as zero, and what symptom obviously alleviated is labeled as △, what symptom was not improved be labeled as ×, the therapeutic effect of 8 treatment groups is as shown in table 1.
Table 1
2,, pale complexion coarse to skin, dark stagnant, sallow therapeutic effect
Select 120 have in various degree that skin is coarse, pale complexion, dark stagnant, sallow 35-55 year man female patient, be divided at random 8 treatment groups (every group of 15 patients).5 treatment group drug administration preparation B1-B5 respectively, 3 matched group drug administration preparation E1-E3 respectively, instructions of taking be every day sooner or later respectively once, each 6g, heat wineization clothes, observing effect after 100 days, compared with before taking medicine, what symptom disappeared completely is labeled as zero, and what symptom obviously alleviated is labeled as △, what symptom was not improved be labeled as ×, the therapeutic effect of 8 treatment groups is as shown in table 2.
Table 2
3, the therapeutic effect to emaciation and sallow complexion
Select 160 male female patients with the patient 35-75 year of the insufficiency of the spleen emaciation and sallow complexion causing, be divided at random 8 treatment groups (every group of 20 people).5 treatment group drug administration preparation B1-B5 respectively, 3 matched group drug administration preparation E1-E3 respectively, instructions of taking be every day sooner or later respectively once, each 6g, warm yellow wineization clothes, observing effect after 100 days, compared with before taking medicine, what symptom disappeared completely is labeled as zero, and what symptom obviously alleviated is labeled as △, what symptom was not improved be labeled as ×, the therapeutic effect of 8 treatment groups is as shown in table 3.
Table 3
Can find out from the measurement result of above experimental example, Chinese medicine composition provided by the invention can improve people's body immunity effectively, and improves weak state, improves human body appearance state.And pharmaceutical preparation of the present invention depends on the particular combinations of each composition, indispensable.
More than describe the preferred embodiment of the present invention in detail; but the present invention is not limited to the detail in above-mentioned embodiment, within the scope of technical conceive of the present invention; can carry out multiple simple variant to technical scheme of the present invention, these simple variant all belong to protection scope of the present invention.
It should be noted that in addition each the concrete technical characterictic described in above-mentioned detailed description of the invention, in reconcilable situation, can combine by any suitable mode.For fear of unnecessary repetition, the present invention is to the explanation no longer separately of various possible compound modes.
In addition, also can carry out combination in any between various embodiment of the present invention, as long as it is without prejudice to thought of the present invention, it should be considered as content disclosed in this invention equally.
Claims (10)
1. a pharmaceutical composition, it is characterized in that, this pharmaceutical composition is prepared from by following raw material: Corium Cervi, Carapax et Plastrum Testudinis, Radix Ginseng, Fructus Lycii, Fructus Hordei Germinatus, Massa Medicata Fermentata, the Radix Polygoni Multiflori, Semen Cuscutae and Poria, wherein, with respect to the Corium Cervi of 100 weight portions, the content of Carapax et Plastrum Testudinis is 50-150 weight portion, the content of Radix Ginseng, the Fructus Lycii fleece-flower root 30-100 weight portion of respectively doing for oneself, Fructus Hordei Germinatus, the content of Massa Medicata Fermentata, Semen Cuscutae and the Poria 20-100 weight portion of respectively doing for oneself.
2. pharmaceutical composition according to claim 1, wherein, with respect to the Corium Cervi of 100 weight portions, the content of Carapax et Plastrum Testudinis is 55-120 weight portion, the content of Radix Ginseng, the Fructus Lycii fleece-flower root 40-90 weight portion of respectively doing for oneself, Fructus Hordei Germinatus, the content of Massa Medicata Fermentata, Semen Cuscutae and the Poria 30-75 weight portion of respectively doing for oneself.
3. pharmaceutical composition according to claim 1 and 2, wherein, the Corium Cervi that described Corium Cervi is Cervus nippon Temminck and/or the Corium Cervi of Cervus elaphus linnaeus.
4. according to the pharmaceutical composition described in any one in claim 1-3, wherein, Carapax et Plastrum Testudinis, Radix Ginseng, Fructus Lycii, Fructus Hordei Germinatus, Massa Medicata Fermentata, the Radix Polygoni Multiflori, Semen Cuscutae and Poria are can be by the powder of the sieve aperture of 80-150 mesh sieve.
5. a pharmaceutical preparation, described pharmaceutical preparation contains active component, and pharmaceutically acceptable adjuvant alternatively, it is characterized in that, and described active component is the pharmaceutical composition described in any one in claim 1-4.
6. pharmaceutical preparation according to claim 5, wherein, described pharmaceutical preparation contains described active component and pharmaceutically acceptable adjuvant, taking the gross weight of described pharmaceutical preparation as benchmark, the content of described active component is 30-80 % by weight, and the content of described adjuvant is 20-70 % by weight.
7. pharmaceutical preparation according to claim 6, wherein, taking the gross weight of described pharmaceutical preparation as benchmark, the content of described active component can be 50-70 % by weight, the content of described adjuvant is 30-50 % by weight.
8. pharmaceutical preparation according to claim 5, wherein, the preparation method of described pharmaceutical preparation comprises, Corium Cervi and Carapax et Plastrum Testudinis are brewed into glue, respectively Radix Ginseng, Fructus Lycii, Fructus Hordei Germinatus, Massa Medicata Fermentata, the Radix Polygoni Multiflori, Semen Cuscutae and Poria is fried into medicinal liquid; Described glue, each medicinal liquid and optional pharmaceutically acceptable adjuvant are mixed.
9. pharmaceutical preparation according to claim 8, wherein, the preparation method of described pharmaceutical preparation also comprises carries out homogenizing, concentrated and dry by the described mixed liquor being mixed to get.
10. the pharmaceutical composition described in any one in claim 1-4, the pharmaceutical preparation in claim 5-9 described in any one is in the application of preparing in health product.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115054646A (en) * | 2022-03-07 | 2022-09-16 | 湖南爱敬堂制药有限公司 | Guilu cake and preparation method thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1174066A (en) * | 1997-07-16 | 1998-02-25 | 迟经惠 | Wulaoqishangsan powder for asthenia of both spleen and kidney |
| CN101983703A (en) * | 2010-11-19 | 2011-03-09 | 齐东华 | Traditional Chinese medicine composition and traditional Chinese medicine preparation |
-
2014
- 2014-05-20 CN CN201410214266.6A patent/CN103977305A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1174066A (en) * | 1997-07-16 | 1998-02-25 | 迟经惠 | Wulaoqishangsan powder for asthenia of both spleen and kidney |
| CN101983703A (en) * | 2010-11-19 | 2011-03-09 | 齐东华 | Traditional Chinese medicine composition and traditional Chinese medicine preparation |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115054646A (en) * | 2022-03-07 | 2022-09-16 | 湖南爱敬堂制药有限公司 | Guilu cake and preparation method thereof |
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Application publication date: 20140813 |