CN103977098B - Hardship hundred tincture for the treatment of skin pruritus - Google Patents

Hardship hundred tincture for the treatment of skin pruritus Download PDF

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Publication number
CN103977098B
CN103977098B CN201410163670.5A CN201410163670A CN103977098B CN 103977098 B CN103977098 B CN 103977098B CN 201410163670 A CN201410163670 A CN 201410163670A CN 103977098 B CN103977098 B CN 103977098B
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plant
treatment
hundred
radix stemonae
radix
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CN103977098A (en
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许世钦
梁玥
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Abstract

The invention discloses hardship hundred tincture for the treatment of skin itching disease.Treatment skin pruritus commonly uses Western medicine antihistaminic, calcium preparation and hormone.Owing to these medicine contraindications are many, often causing drowsiness, weak and other side reactions, affect orthobiosis and the work of patient, chronic patient is difficult to adhere to treatment.The present invention is by Radix rhamni crenatae 13 parts, the parasitic 13 parts of preparations of the Radix Stemonae, and method is: taking the above-mentioned clean raw material powder that is dried and be broken into coarse grain, being soaked in concentration is 75%(V/V) 10 30 parts of ethanol in, soaks 7 15 days, taking-up filtration, filtrate is packed and be get final product.The present invention has heat-clearing and toxic substances removing, parasite killing dampness removing, antipruritic effect, is used for the skin itching disease treating wind, damp causes.By clinical verification, being sprayed at affected part by the present invention, treat skin itching disease patient 133 example, achieve preferable clinical efficacy, effective percentage reaches 96.3%, does not finds local and systemic anaphylaxis phenomenon, drug safety during medication.

Description

Hardship hundred tincture for the treatment of skin pruritus
Technical field
The present invention relates to treat hardship hundred tincture of skin pruritus, belong to external Chinese medicament preparing technical field.
Background technology
Skin pruritus is a kind of dermatosis, belongs to psychoneural dermatoses, is a kind of skin neurosis illness.Face On bed, only skin pruritus is referred to as pruritus without primary cutaneous impairer, belongs to the category of the traditional Chinese medical science " pruritus ".Clinically Can be divided into general skin pruritus and limitation skin pruritus, the latter is confined to anus and external genital more.General skin pruritus Common cause is endocrine disturbance and pruritus hiemalis, and hepatorenal disease, malignant tumor and spirituality factor also can cause pruritus, Excessively cleaning skin causes skin degreaser drying to produce pruritus.Common sympton has violent pruritus: is found in whole body or is confined to Anus, scrotum or female genital, for paroxysmal, gargalesthesia acutely, often increase the weight of at night, impact sleep.It is more than that patient commonly uses hands scratching; Secondary cases skin lesion: because scratching excessively occurs scratch, blood stasis, with the passing of time may occur in which eczematization, lichenification and pigmentation.Control Treat skin pruritus and commonly use Western medicine antihistaminic (terfenadine, clarityne) calcium preparation (common calcium tablet, necessity gives injection) and hormone (containing ground Plug rice conifer) etc..Owing to these medicine contraindications are many, often cause drowsiness, weak and other side reactions, affect the normal raw of patient Living and work, chronic patient is difficult to adhere to treatment.The traditional Chinese medical science is thought, ailment said due to cold or exposure, damp, pathogenic heat, blood deficiency, worm are excessive etc. for skin pruritus The main cause caused a disease, treatment should be held up with dispelling wind damp eliminating, heat-clearing and toxic substances removing, blood enriching and dryness moistening, blood circulation promoting and blood stasis dispelling as principle to reach to get rid of evils The most antipruritic effect.Chinese traditional treatment skin pruritus endo-medicine: Radix Saposhnikoviae and Periostracum Cicadae have dispelling wind, heat clearing away, antipruritic effect, typically For treating anaphylaxis dermatosis, then the medicine such as compatibility Radix Semiaquilegiae, Rhizoma Smilacis Glabrae, Cortex Dictamni, to strengthen heat clearing away, to dehumidify, detoxify Effect.Liniment: the repellent antipruritics such as Flos Lonicerae, Folium Nelumbinis, Aloe, the external application Chinese medicine of blood circulation promoting and blood stasis dispelling composition are smash out, external application, Mainly can play the effect of removing heat from blood, heat clearing away, removing toxic substances, the eczema oozed out for acute nothing.It is exactly also directly to smear, soak Medicine: taking Herba Portulacae and decoct 20 minutes, the used time gets it filled water soak affected part, every day 2-3 time, is mainly used in acute exudative eczema. These medicines, are respectively provided with certain effect to alleviating skin pruritus, but because the cause of disease of skin pruritus is varied, To the skin pruritus caused due to wind, damp, the medicament utilizing effective Chinese medicine to prepare directly acts at pruritus, for alleviating scabies Itching, effect becomes apparent from, and this is also the effective way expanding treatment by Chinese herbs.
Summary of the invention
It is an object of the invention to provide hardship hundred tincture for the treatment of skin pruritus, utilize the reasonable compatibility of Chinese herbal medicine, system Standby one-tenth external-use tincture, directly acts on patient affected part, and reduction of patient is painful, overcomes existing treatment skin pruritus disease drug to be easily generated The deficiency of side effect.
Foregoing invention purpose, is achieved through the following technical solutions, treatment skin pruritus hardship hundred tincture, by under State raw material to be prepared from:
Radix rhamni crenatae 1-3 part Radix Stemonae parasitism 1-3 part;
The preparation method of described bitter hundred tinctures is:
Taking the above-mentioned clean raw material powder that is dried and be broken into coarse grain, being soaked in concentration is 75%(V/V) 10-30 part ethanol in, soak 7- 15 days, taking out and filter, filtrate is packed and be get final product.
The bitter Radix Pruni Salicinae of described Radix rhamni crenatae another name, refers to Rhamnaceae plant Radix rhamni crenataeFrangula crenata (Sieb. et Zucc.) dry root of Miq;
Described Radix Stemonae parasitism refers to Ceratonia siliqua and colonizes in the Radix StemonaeStemona sessilifolia (Miq.) Miq plant On the new plant that grows out, cultural method is:
(1) standby at the Ceratonia siliqua seed selecting fresh solid health annual 10-12 month;
(2) take poultry-dung to stir with equal portions cattle manure, be dried to the pasty state fertilizer presenting viscosity standby;
(3) by a weight portion plant ash addition 1-3 weight parts water stirs, after plant ash precipitates, supernatant is taken The liquid that is sterilized is standby;
(4) the position disinfectant solution sterilization to the host plant little bifurcated of Radix Stemonae plant, then with pasty state fertilizer Ceratonia siliqua Seed is bonded on the position of the host plant little bifurcated of Radix Stemonae plant, with thin film the ground being bonded with Ceratonia siliqua seed on Radix Stemonae plant Side wraps up, and in 30-60 days, every night, water spray kept moistening, until sprouting.
Taking the present invention of above-mentioned measure, Radix rhamni crenatae has heat-clearing and toxic substances removing, parasite killing dampness removing effect.It is mainly used in treating scabies Skin ulcer;Stubborn dermatitis;Furuncle;Eczema;Urticaria;Leprosy dysentery head;Traumatic injury.Radix Stemonae parasitism has killing parasites for relieving itching effect, is used for treating skin Skin pruritus.Both combine and are prepared as tincture, are just provided with the effect for the treatment of skin pruritus, the skin caused for wind, damp Skin pruritus.For verifying the clinical effectiveness of the present invention, 133 example skin pruritus patients are carried out by Herba Taxilli institute of materia medica, Beihai Clinical treatment, the result is as follows:
(1) clinical data: take clinical case 133 example, wherein senile pruritus 46 example, pruritus hiemalis 64 example, summer scabies Itch disease 23 example, women 62 example, male 71 example, age 3-61 year.
(2) pruritus position: extremity 73 example, trunk, pudendum 60 example.
(3) Therapeutic Method: use tincture of the present invention to be sprayed directly on to affected part, spray medicine twice every day, six days is a course for the treatment of, medication Rear observation local skin and systemic side effects in time.
(4) observation of curative effect:
(a) criterion of therapeutical effect: after medication one course for the treatment of.
Cure: clinical symptoms is wholly absent.
Take a turn for the better: clinical symptom relief.
Invalid: clinical symptoms and sign are without any improvement or increase the weight of.
(b) efficacy analysis:
133 example skin pruritus therapeutic effect
Sick kind Number of cases Cure Take a turn for the better Invalid
Senile pruritus 46 29 13 4
Pruritus hiemalis 64 57 6 1
Pruritus aestivalis 23 21 2 0
Amount to 133 107 21 5
Effective percentage 80.5% 15.8% 3.7%
Side effect is observed: Local out dressing has no local skin allergic phenomena;Local out dressing has no systemic adverse reactions.
(4) conclusion: from above-mentioned Clinical results, the present invention has heat-clearing and toxic substances removing, parasite killing dampness removing, antipruritic merit Effect, with trypsin method of the present invention in affected part, treats skin pruritus patient 133 example, achieves preferable clinical efficacy, and effective percentage reaches To 96.3%, during medication, do not find local and systemic anaphylaxis phenomenon, drug safety.
Detailed description of the invention
Embodiment 1
(1) composition of raw materials:
Parasitic 10 kilograms of 10 kilograms of Radixs Stemonae of Radix rhamni crenatae;
(2) preparation method:
Taking the above-mentioned clean raw material pulverizing that is dried and become particle diameter 1-3 millimeter coarse grain, being soaked in concentration is 75%(V/V) 100 kilograms of wine In essence, soaking 7-15 days, take out and filter, filtrate is packed and be get final product.
Embodiment 2
(1) composition of raw materials:
Parasitic 30 kilograms of 10 kilograms of Radixs Stemonae of Radix rhamni crenatae;
(2) preparation method:
Taking the above-mentioned clean raw material pulverizing that is dried and become particle diameter 1-3 millimeter coarse grain, being soaked in concentration is 75%(V/V) 300 kilograms of wine In essence, soaking 7-15 days, take out and filter, filtrate is packed and be get final product.
Embodiment 3
(1) composition of raw materials:
Parasitic 10 kilograms of 30 kilograms of Radixs Stemonae of Radix rhamni crenatae;
(2) preparation method:
Taking the above-mentioned clean raw material pulverizing that is dried and become particle diameter 1-3 millimeter coarse grain, being soaked in concentration is 75%(V/V) 300 kilograms of wine In essence, soaking 7-15 days, take out and filter, filtrate is packed and be get final product.
Embodiment 4
(1) composition of raw materials:
Parasitic 20 kilograms of 10 kilograms of Radixs Stemonae of Radix rhamni crenatae;
(2) preparation method:
Taking the above-mentioned clean raw material pulverizing that is dried and become particle diameter 1-3 millimeter coarse grain, being soaked in concentration is 75%(V/V) 200 kilograms of wine In essence, soaking 7-15 days, take out and filter, filtrate is packed and be get final product.
Embodiment 5
(1) composition of raw materials:
Parasitic 10 kilograms of 20 kilograms of Radixs Stemonae of Radix rhamni crenatae;
(2) preparation method:
Taking the above-mentioned clean raw material pulverizing that is dried and become particle diameter 1-3 millimeter coarse grain, being soaked in concentration is 75%(V/V) 200 kilograms of wine In essence, soaking 7-15 days, take out and filter, filtrate is packed and be get final product.

Claims (1)

1. treat skin pruritus hardship hundred tincture, it is characterised in that described bitter hundred tinctures prepared by following weight parts raw material and Become:
Radix rhamni crenatae 1-3 part Radix Stemonae parasitism 1-3 part;
The preparation method of described bitter hundred tinctures is:
Taking the above-mentioned clean raw material powder that is dried and be broken into coarse grain, being soaked in concentration is 75%(V/V) 10-30 part ethanol in, soak 7-15 My god, to take out and filter, filtrate is packed and be get final product;
Described Radix Stemonae parasitism refers to Ceratonia siliqua and colonizes in the new plant grown out on Radix Stemonae plant, and cultural method is:
(1) standby at the Ceratonia siliqua seed selecting fresh solid health annual 10-12 month;
(2) take poultry-dung to stir with equal portions cattle manure, be dried to the pasty state fertilizer presenting viscosity standby;
(3) by a weight portion plant ash addition 1-3 weight parts water stirs, after plant ash precipitates, take supernatant and obtain Disinfectant solution is standby;
(4) the position disinfectant solution sterilization to the host plant little bifurcated of Radix Stemonae plant, then with pasty state fertilizer Ceratonia siliqua seed It is bonded on the position of the host plant little bifurcated of Radix Stemonae plant, with thin film the local bag being bonded with Ceratonia siliqua seed on Radix Stemonae plant Wrapping, in 30-60 days, every night, water spray kept moistening, until sprouting.
CN201410163670.5A 2014-04-23 2014-04-23 Hardship hundred tincture for the treatment of skin pruritus Expired - Fee Related CN103977098B (en)

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CN201410163670.5A CN103977098B (en) 2014-04-23 2014-04-23 Hardship hundred tincture for the treatment of skin pruritus

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Application Number Priority Date Filing Date Title
CN201410163670.5A CN103977098B (en) 2014-04-23 2014-04-23 Hardship hundred tincture for the treatment of skin pruritus

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CN103977098B true CN103977098B (en) 2016-08-31

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Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
百部擦剂治疗皮肤瘙痒症200例;陈文杰等;《中国民间疗法》;20010331;第9卷(第3期);第23-24页 *
皮肤瘙痒的发生机理与中医辨证施治相关性探讨;杨慧敏等;《中国中西医结合皮肤性病学杂志》;20061231;第5卷(第3期);第175-181页 *

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