CN103977069A - Traditional Chinese medicine oral liquid for treating nephritis - Google Patents

Abstract

The invention discloses a traditional Chinese medicine oral liquid for treating nephritis. The traditional Chinese medicine oral liquid is composed of fresh orthosiphon aristatus, fresh triquetrous tadehagi herb and fresh shortstyle cratoxylum, the preparation method comprises the following steps: 1)taking the raw materials, adding water with 3-5 times of amount of the raw materials, immersing for 30-60 minutes, heating to the temperature of 100 DEG C for extracting for 30-60 minutes, repeatedly extracting for once, merging the twice extracts and filtering to obtain a filtrate, concentrating the filtrate to the degree that the relative is 1.10-1.15 at 60 DEG C to obtain a concentrate for standby, and 2)adding water in the concentrate, heating to a boiling liquid so that each milliliter of the liquid contains 3-5g of crude drug, and packaging. The traditional Chinese medicine oral liquid has the functions of clearing heat and detoxifying, removing food retention and disinhibiting dampness, clearing heat and removing moisture, expelling stone and clearing damp, and inducing diuresis to reduce edema, and is used for treating acute nephritis and early nephritis. Through clinical application of 43 cases of patients of acute nephritis, the traditional Chinese medicine oral liquid can be used for acute nephritis and early nephritis. The traditional Chinese medicine oral liquid has good clinic curative effect, the effective rate can reach 100%, no phenomenon of local anaphylaxis or anaphylaxis for whole body is discovered during a medication period.

Description

A kind of Chinese medicine oral liquid for the treatment of nephritis

Technical field

What the present invention relates to is a kind of Chinese medicine oral liquid for the treatment of nephritis, belongs to Chinese drug preparation technique field.

Background technology

Nephritis is to change into basic feature with nephridial tissue structure generation inflammatory, causes one group of kidney disease of renal hypofunction in various degree, can be caused by Different types of etiopathogenises.The main manifestations of nephritis: weak, flank pain, poor appetite, gross hematuria, edema, hypertension, renal dysfunction, hypourocrinia, congestive heart failure etc.To the Therapeutic Principle of nephritis, be should lie up in acute stage, after clinical symptoms takes a turn for the better, progressively increase activity.Acute stage, should give below low salt diet 3g every day.Normal renal function person does not need limit protein matter to enter amount, but answers during azotemia limit protein matter to take in, and take high-quality animal proteinum as main.Oliguria person answers confined liquid to enter amount.For treatment focus of infection.According to clinical symptoms symptomatic treatment, inducing diuresis to remove edema, blood pressure lowering, complication prevention.Symptomatic treatment diuresis, detumescence, blood pressure lowering, conventional thiazide diuretic.Nephritis mostly empirical, Chinese medicine, according to dialectical wind and cold, the wind heat, damp and hot of being divided into, gives respectively lung qi dispersing diuresis, the therapies such as removing pathogenic heat from blood and toxic substance from the body.For acute nephritis, if treatment is not in time, just likely make PD, further worsen, so in nephritis acute stage, just should promptly treat.Motherland's medical science is a great treasure-house, the potential of many Chinese herbal medicine also can not get excavating, utilizing Chinese herbal treatment nephritis is an effective approach, excavates a kind ofly can treat in time the medicine that morbidity also belongs in early days acute stage nephritis, for treatment acute nephritis, is very important.

Summary of the invention

The object of this invention is to provide a kind of Chinese medicine oral liquid for the treatment of nephritis, the heat-clearing and toxic substances removing, the removing food stagnancy dampness removing that utilize the present invention to have, clearing heat and removing internal wetness, calculus diuretic, the function of inducing diuresis to remove edema, treatment acute nephritis, is controlled at the initial phase disease.

To achieve these goals, the present invention has taked following technical proposals, and a kind of Chinese medicine oral liquid for the treatment of nephritis is to be prepared from by following weight parts raw material:

The parasitic 1-3 part of the fresh Herba Desmodii Triquetri (Herba Tadehagi Triquetri) 1-3 of fresh Herba clerodendranthi spicati 1-3 part part cadmium yellow beef tea;

Preparation method:

(1) get described raw material and add 3-5 times of water gaging to soak 30-60 minute, be heated to 100 ℃ and extract 30-60 minute, repeat to extract once, merging extracted twice liquid filters, obtain filtrate, it is 1.10-1.15 that filtrate is concentrated to 60 ℃ of heat survey relative densities, obtains concentrated solution standby;

(2) get concentrated solution and add water post-heating to the dosing of boiling, make every milliliter contained amount 3-5 gram, pack and get final product.

Described Folium cratoxyli ligustrini is parasitic, refers to Ceratonia siliqua and colonizes in Guttiferae cattle fogfruit cattle wood cratoxylon ligustrinum(Spach) plant of growth on Blume. tree, cultural method is:

(1) selecting the Ceratonia siliqua seed of fresh solid health standby in 10-12 month every year;

(2) get poultry-dung and equal portions cattle manure stirs, be dried to that to present the pasty state fertilizer of viscosity standby;

(3) a weight portion plant ash is added in 1-3 weight parts water and stirred, after plant ash precipitation, get the supernatant liquid that is sterilized standby;

(4) sterilized with disinfectant solution in the position of sprig bifurcated on host plant cattle ebon, then with pasty state fertilizer, Ceratonia siliqua seed is bonded on the position of sprig bifurcated on host plant cattle ebon, with dogstail or book film, the place that is bonded with Ceratonia siliqua seed on cattle ebon is wrapped up, in 30-60 days, every night, water spray kept moistening, until sprout.

Take the present invention of above-mentioned measure, by Herba clerodendranthi spicati, Herba Desmodii Triquetri (Herba Tadehagi Triquetri) and Folium cratoxyli ligustrini parasitism, as raw material, prepared, Herba clerodendranthi spicati, original name: kidney tea, formal name used at school: clerodendranthus spicatus(Thunb.) C. Y. Wu, Herba clerodendranthi spicati function: clearing heat and removing internal wetness, calculus diuretic, refrigerant antiinflammatory, is mainly used in treating acute and chronic nephritis, cystitis, lithangiuria and rheumatic arthritis.Herba Desmodii Triquetri (Herba Tadehagi Triquetri) is pulse family beggar-ticks plant gourd tea desmodium triquetrum(L.) DC., has the effects such as heat-clearing and toxic substances removing, removing food stagnancy dampness removing, parasite killing are anticorrosion, can be used for preventing heatstroke, treatment cold, fever, laryngopharynx swelling and pain, nephritis etc.Folium cratoxyli ligustrini is called yellow young tea leaves, is Guttiferae cattle fogfruit cattle wood cratoxylon ligustrinum(Spach) Blume., is used as medicine with root, bark, tender leaf, has expelling summer-heat heat clearing away, the dampness removing stagnant function that disappears.For flu, heatstroke heating, acute gastroenteritis, jaundice.The present invention who is prepared by above-mentioned three kinds of raw materials has heat-clearing and toxic substances removing, removing food stagnancy dampness removing, clearing heat and removing internal wetness, calculus diuretic, the function of inducing diuresis to remove edema, is used for the treatment of acute nephritis, nephritis from the beginning of.Herba Taxilli institute of materia medica, Beihai has carried out clinical practice checking to 43 routine acute nephritis patients with the present invention, and checking is reported as follows:

(1) clinical data: get clinical case 43 examples, by acute nephritis diagnostic criteria diagnosis, be acute nephritis.

(2) clinical symptoms: all have urine abnormal, hematuria, blepharoedema or lower limbs edema, hypertension and renal dysfunction, the clinical symptoms of oliguria.

(3) Therapeutic Method: use oral liquid of the present invention oral, day takes three times, each 30-50 milliliter, ten days is a course for the treatment of, observes in time systemic side effects after medication.

(4) observation of curative effect:

(a) criterion of therapeutical effect: medication is observed clinical symptoms after one course for the treatment of.

Cure: clinical symptoms disappears completely.

Take a turn for the better: clinical symptom relief, sign is improved.

Invalid: clinical symptoms and sign are without any improvement or increase the weight of.

(b) efficacy analysis:

43 routine acute nephritis therapeutic effect

Main suit's symptom	Number of cases	Cure	Take a turn for the better	Invalid
					Acute nephritis hematuria is abnormal	9	8	1	0
Acute nephritis edema	18	15	3	0
					Acute nephritis urine amount is few	11	11	0	0
Acute nephritis hypertension	5	5	0	0
					Amount to	43	39	4	0
Effective percentage	?	90.7%	9.3%	0

Side effect is observed: have no systemic adverse reactions.

(4) conclusion: from above-mentioned Clinical results, the present invention has heat-clearing and toxic substances removing, removing food stagnancy dampness removing, clearing heat and removing internal wetness, calculus diuretic, the function of inducing diuresis to remove edema, the present invention is for oral administration, day takes three times, each 30-50 milliliter, is used for the treatment of acute nephritis, nephritis from the beginning of.Obtained good clinical efficacy, effective percentage reaches 100%, does not find part and systemic anaphylaxis phenomenon, drug safety during medication.

The specific embodiment

Embodiment 1

Formula:

Parasitic 20 kilograms of 20 kilograms of cadmium yellow beef teas of 10 kilograms of fresh Herba Desmodii Triquetri (Herba Tadehagi Triquetri)s of fresh Herba clerodendranthi spicati;

Preparation method:

(1) get described raw material and add 150 kg of water to soak 30-60 minute, be heated to 100 ℃ of extraction 30-60 minute, repeat to extract once, merge extracted twice liquid and filter, obtain filtrate, it is 1.10 that filtrate is concentrated to 60 ℃ of heat survey relative densities, obtains concentrated solution standby;

(2) get concentrated solution and add water post-heating to the dosing of boiling, make every milliliter contained amount 3-5 gram, pack and get final product.

Embodiment 2

Formula:

Parasitic 20 kilograms of 10 kilograms of cadmium yellow beef teas of 30 kilograms of fresh Herba Desmodii Triquetri (Herba Tadehagi Triquetri)s of fresh Herba clerodendranthi spicati;

Preparation method:

(1) get described raw material and add 300 kg of water to soak 30-60 minute, be heated to 100 ℃ of extraction 30-60 minute, repeat to extract once, merge extracted twice liquid and filter, obtain filtrate, it is 1.15 that filtrate is concentrated to 60 ℃ of heat survey relative densities, obtains concentrated solution standby;

(2) get concentrated solution and add water post-heating to the dosing of boiling, make every milliliter contained amount 3-5 gram, pack and get final product.

Embodiment 3

Formula:

Parasitic 20 kilograms of 20 kilograms of cadmium yellow beef teas of 20 kilograms of fresh Herba Desmodii Triquetri (Herba Tadehagi Triquetri)s of fresh Herba clerodendranthi spicati;

Preparation method:

(1) get described raw material and add 180 kg of water to soak 30-60 minute, be heated to 100 ℃ of extraction 30-60 minute, repeat to extract once, merge extracted twice liquid and filter, obtain filtrate, it is 1.13 that filtrate is concentrated to 60 ℃ of heat survey relative densities, obtains concentrated solution standby;

(2) get concentrated solution and add water post-heating to the dosing of boiling, make every milliliter contained amount 3-5 gram, pack and get final product.

Embodiment 4

Formula:

Parasitic 30 kilograms of 30 kilograms of cadmium yellow beef teas of 20 kilograms of fresh Herba Desmodii Triquetri (Herba Tadehagi Triquetri)s of fresh Herba clerodendranthi spicati;

Preparation method:

(1) get described raw material and add 320 kg of water to soak 30-60 minute, be heated to 100 ℃ of extraction 30-60 minute, repeat to extract once, merge extracted twice liquid and filter, obtain filtrate, it is 1.15 that filtrate is concentrated to 60 ℃ of heat survey relative densities, obtains concentrated solution standby;

(2) get concentrated solution and add water post-heating to the dosing of boiling, make every milliliter contained amount 3-5 gram, pack and get final product.

Claims (1)

1. treat a Chinese medicine oral liquid for nephritis, it is characterized in that described Chinese medicine oral liquid is to be prepared from by following weight parts raw material:

The parasitic 1-3 part of the fresh Herba Desmodii Triquetri (Herba Tadehagi Triquetri) 1-3 of fresh Herba clerodendranthi spicati 1-3 part part cadmium yellow beef tea;

Preparation method:

(1) get described raw material and add 3-5 times of water gaging to soak 30-60 minute, be heated to 100 ℃ and extract 30-60 minute, repeat to extract once, merging extracted twice liquid filters, obtain filtrate, it is 1.10-1.15 that filtrate is concentrated to 60 ℃ of heat survey relative densities, obtains concentrated solution standby;

(2) get concentrated solution and add water post-heating to the dosing of boiling, make every milliliter contained amount 3-5 gram, pack and get final product.